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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SAMD4B-SLFN5 (FusionGDB2 ID:79093)

Fusion Gene Summary for SAMD4B-SLFN5

check button Fusion gene summary
Fusion gene informationFusion gene name: SAMD4B-SLFN5
Fusion gene ID: 79093
HgeneTgene
Gene symbol

SAMD4B

SLFN5

Gene ID

55095

162394

Gene namesterile alpha motif domain containing 4Bschlafen family member 5
SynonymsSMGB|Smaug2-
Cytomap

19q13.2

17q12

Type of geneprotein-codingprotein-coding
Descriptionprotein Smaug homolog 2SAM domain-containing protein 4Bsmaug 2smaug homolog Bsterile alpha motif domain-containing protein 4Bschlafen family member 5
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000594204, ENST00000314471, 
ENST00000596368, ENST00000598913, 
ENST00000299977, ENST00000542451, 
ENST00000592325, 
Fusion gene scores* DoF score7 X 5 X 6=2101 X 1 X 1=1
# samples 81
** MAII scorelog2(8/210*10)=-1.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: SAMD4B [Title/Abstract] AND SLFN5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSAMD4B(39847729)-SLFN5(33591202), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SAMD4B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLFN5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-EA-A3HR-01ASAMD4Bchr19

39847729

-SLFN5chr17

33591202

+
ChimerDB4CESCTCGA-EA-A3HR-01ASAMD4Bchr19

39847729

+SLFN5chr17

33591202

+


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Fusion Gene ORF analysis for SAMD4B-SLFN5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000594204ENST00000299977SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+
3UTR-intronENST00000594204ENST00000542451SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+
3UTR-intronENST00000594204ENST00000592325SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+
5CDS-intronENST00000314471ENST00000542451SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+
5CDS-intronENST00000314471ENST00000592325SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+
5CDS-intronENST00000596368ENST00000542451SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+
5CDS-intronENST00000596368ENST00000592325SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+
5CDS-intronENST00000598913ENST00000542451SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+
5CDS-intronENST00000598913ENST00000592325SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+
In-frameENST00000314471ENST00000299977SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+
In-frameENST00000596368ENST00000299977SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+
In-frameENST00000598913ENST00000299977SAMD4Bchr19

39847729

+SLFN5chr17

33591202

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000598913SAMD4Bchr1939847729+ENST00000299977SLFN5chr1733591202+98415363402073577
ENST00000314471SAMD4Bchr1939847729+ENST00000299977SLFN5chr1733591202+10536123110352768577
ENST00000596368SAMD4Bchr1939847729+ENST00000299977SLFN5chr1733591202+9579274781811577

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000598913ENST00000299977SAMD4Bchr1939847729+SLFN5chr1733591202+0.0004518040.99954814
ENST00000314471ENST00000299977SAMD4Bchr1939847729+SLFN5chr1733591202+0.0004640450.99953604
ENST00000596368ENST00000299977SAMD4Bchr1939847729+SLFN5chr1733591202+0.0004152810.99958473

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Fusion Genomic Features for SAMD4B-SLFN5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SAMD4Bchr1939847729+SLFN5chr1733591201+1.18E-081
SAMD4Bchr1939847729+SLFN5chr1733591201+1.18E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SAMD4B-SLFN5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:39847729/chr17:33591202)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLFN5chr19:39847729chr17:33591202ENST0000029997725578_585379892.0Nucleotide bindingATP
TgeneSLFN5chr19:39847729chr17:33591202ENST0000059232502578_5850339.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSAMD4Bchr19:39847729chr17:33591202ENST00000314471+516299_37265695.0DomainNote=SAM


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Fusion Gene Sequence for SAMD4B-SLFN5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>79093_79093_1_SAMD4B-SLFN5_SAMD4B_chr19_39847729_ENST00000314471_SLFN5_chr17_33591202_ENST00000299977_length(transcript)=10536nt_BP=1231nt
GGTCGGTGCGGGAGGAGGGAGGGGAGCTTGCGGGCCCGAGAGGGGGCGACGGCGGCGGCGGTGGCCTGAGGAGGCCCGAGCGGCGGCGGT
GGCGGCGAAGGCCGAGGCGTCTAGGTGTTTTTGGAAGAGCTGCAGCCTTTGAAGAAACATCTCTTGATGATGATATCATAGACTCCTTCC
TACTGGGCAGATGAGGCAGAATGGGGCACAGTAGTTCCAGCAAAAATCCAGAGAGGACTATCCTTGGCCAGGCTTTACCCCATGTCCACT
TCTGGAGCCAAGAAAGACAGTTCCTTCTCCAAGGGGAACCCAGGGTGTTGATACTAGAAGATGGAAATGGATACAGTAAGATGCTGCCAC
AGTGAGATGCCTCACCCAGGTCTCCCTCTGTCACTTCAGCCAAGCACATGGGATAGAAAGTAGCAGGCGGCCTCTGGCCCTTTAATGGAA
GAGGGCCATCCAGTCCTCTCCAGTTAACATCTAGACCGAACACAAAGCATCCTTCTCTCATCCAGAAGACATAGGAACCCTACCTTCAGG
GATGATTTTTTTTTAACAGTGAAATCTTAAAAGTAACTGTTTCACTAAAGCCTCCAGTATTTACTGAAGACTGTCAGAATCATCCTCCAT
CACTAGATCTTCTCCACCAGTCATGTTCCCTGAGCAGTGGGGTGGCTTGAAGGTATAAACCAGAGAGGCCCAAGGGAGGGATAGTTAGCA
GACTTCTGGTCTTTTTCTAGTTTGTGCTCTTCTGTTCCAAGGACCACAGGATTCTTCTCATCGCAGTGCTCCAGGCAGCCACTACCAATC
GATTGGAGTTAGCCTGTGAGGAAACTGGAGAGGCGTGGCTGGACCAAGACCTCCCCCCATGTGAGCAGGCTTCCTCCTCCCCCAACAACC
GTTGCCACCACGCCCAGAAACGTCCTTAAGCCCTGGCCCTCAGGGGAAAGGTAACAGGAGGCCAGAGCCGGGACCATGTGACGGCGCTGG
CCCTCGCCACCGCCGTCCCCCGACCCTGGCCCCAGGCCCGGCACCATGATGTTCCGAGACCAGGTGGGCATCCTCGCTGGCTGGTTCAAA
GGCTGGAATGAGTGTGAGCAGACAGTGGCCCTCCTGTCACTTCTGAAACGGGTCACCCGTACCCAGGCCCGCTTCCTGCAGCTCTGCCTG
GAGCACTCACTGGCGGACTGCAATGACATCCACCTGCTGGAGTCGGAGGCCAACAGTGCTGTATTTTCAGACAGAGTGGTATATACTCCA
GAAAGCCTCTACAAGGAACTCTTCTCACAACATAAAGGACTCAGAGACTTAATAAATACAGAAATGCGCCCTTTCTCTCAAGGAATATTG
ATTTTTTCTCAAAGCTGGGCTGTGGATTTAGGTCTGCAAGAGAAGCAGGGAGTCATCTGTGATGCTCTTCTAATTTCCCAGAACAACACC
CCTATTCTCTACACCATCTTCAGCAAGTGGGATGCGGGGTGCAAGGGCTATTCTATGATAGTTGCCTATTCTTTGAAGCAGAAGCTGGTG
AACAAAGGCGGCTACACTGGGAGGTTATGCATCACCCCCTTGGTCTGTGTGCTGAATTCTGATAGAAAAGCACAGAGCGTTTACAGTTCG
TATTTACAAATTTACCCTGAATCCTATAACTTCATGACCCCCCAGCACATGGAAGCCCTGTTACAGTCCCTCGTGATAGTCTTGCTTGGG
TTCAAATCCTTCTTAAGTGAAGAGCTGGGCTCTGAGGTTTTGAACCTACTGACAAATAAACAGTATGAGTTGCTTTCAAAGAACCTTCGC
AAGACCAGAGAGTTGTTTGTTCATGGCTTACCTGGATCAGGGAAGACTATCTTGGCTCTTAGGATCATGGAGAAGATCAGGAATGTGTTT
CACTGTGAACCGGCTAACATTCTCTACATCTGTGAAAACCAGCCCCTGAAGAAGTTGGTGAGTTTCAGCAAGAAAAACATCTGCCAGCCA
GTGACCCGGAAAACCTTCATGAAAAACAACTTTGAACACATCCAGCACATTATCATTGATGACGCTCAGAATTTCCGTACTGAAGATGGG
GACTGGTATGGGAAAGCAAAGTTCATCACTCAGACAGCAAGGGATGGCCCAGGAGTTCTCTGGATCTTTCTGGACTACTTTCAGACCTAT
CACTTGAGTTGCAGTGGCCTCCCCCCTCCCTCAGACCAGTATCCAAGAGAAGAGATCAACAGAGTGGTCCGCAATGCAGGTCCAATAGCT
AATTACCTACAACAAGTAATGCAGGAAGCCCGACAAAATCCTCCACCTAACCTCCCCCCTGGGTCCCTGGTGATGCTCTATGAACCTAAA
TGGGCTCAAGGTGTCCCAGGCAACTTAGAGATTATTGAAGACTTGAACTTGGAGGAGATACTGATCTATGTAGCGAATAAATGCCGTTTT
CTCTTGCGGAATGGTTATTCTCCGAAGGATATTGCTGTGCTTTTCACCAAAGCAAGTGAAGTGGAAAAATATAAAGACAGGCTTCTAACA
GCAATGAGGAAGAGAAAACTGTCTCAGCTCCATGAGGAGTCTGATCTGTTACTACAGATCGGTGATGCGTCGGATGTTCTAACCGATCAC
ATTGTGTTGGACAGTGTCTGTCGATTTTCAGGCCTGGAAAGAAATATCGTGTTTGGAATCAATCCAGGAGTAGCCCCACCGGCTGGGGCC
TACAATCTTCTGCTCTGTTTGGCTTCTAGGGCAAAAAGACATCTGTATATTCTGAAGGCTTCTGTGTGACAGGAAACCCAAGCCTAAGAA
ACAATTAAGTGGTTCTCATCTCTAATTAACTGTGAAACCATTTAATCCAAACATGTAAGCACACACTCACTTATTAAGTCACATACTTTT
CTAGGTGCTGGGGATTGAGAACGAATCGATGTAAGATTCCTCCTTTAGGGCAGAGACAGACCACTGACAAATACACAGATAGACAAGGAA
TTTCCCATGGTAAAAAGGGATATCAGTAATTAGAGGACCGTGAGACTCAGAGATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGC
GCGCGCGCACGTGCACATGTGTGTAGGTAGATGGAGGGGGTGATTATTTTGGGTGGTCAGGGAAGTGCTCAGTGAGGGAAGAACTTGTCA
TGAGAATCTCTGAGCGTGCCAGGCAGACTCGGATATTTTTATAAATTTTTAACATGGCCACTTGCAGAAGAGCTTGAATGGGACGTGCAG
CGAGAATGTGAAGGATGGAGCAGGTAGCTCATCTGGCCTTGTAGGTGCCGGGAACGGGCAAGACATGTTTTGAAATGTAAGATCACAGAC
TGTTTTTTGCAAGACCACATTATATTACTTTATTATTTTCTGCTTTTTCTTTTAACGACATTAGTGTTTTTGATCACTATATTTTAAAAT
GCTTTTTGTGAGCCTTTTGGTTATGTGGAATCTGTTCCTTAGCTCTGATTTTTTATTCTTATGGAGCGTCTTAGGTTACTACATGAAGGT
AAGACTGCCACAGTCCCCCAGGGAGGCACACTGTGTTTTACTGATTGATTTGAAGATGATAGAGAGCCTAGGGGGATGAGTCTATTGGAC
TCAAAGGTTACATTTTGTTTTTCCATTTAATTTAATAATCAACAAAACGACAAAGTCAGTTTAATATCTTTCTTCTGCTGAGTCTTCAGG
ATGTTAGCTAGTCTTTCAAAAGCCATTGCTACAAAAGTGCAAATTTCTCATTTCCTGTGGGTCTCTAGAAACTCTCTCAATATTTAAAGC
CAAACAAATCCATCTTTTCTGAGAGACAGAAACTAAAAAATTCAGAGTTAATTCACTATTAAAAACAGCAAGGCCCTGCTATTTCCCAAG
AATAAAGAAATTTAAAATTCTCATTGTAAGAAGTATGAACTTGAAGCTAGAATTGGTTTATTTCTGGCAGCTACTTACAATATTAAGAAC
TTTACTTTTTAAATTTGAGACAATTTCACAGGAAAGCAAGAAATTAGTCTATTGTGAAATGTTTTTACAACTAACTTGGAATATACTGCA
AATCACTAGTAAGTAGAGACACATTTAAGATAAAATGATTAATAAAACAATTGGTAATTCTGAATAAGGATCTGAATAAATCCAGATCAC
AGACTGTTCCTTTACCAATATGTAAAAGAATGTGCAAAATTAGTAAAAATATACCCAAAAATTTACCAGCAACAGAGAAGCAAAGAATGG
AGTTCAACCTTACACTATAAACATCTAATAGATATGTATGAAAATTTAAAAACTAGAAAAGGTTGGGCATGGTGGCTCATGCTTGTGATC
CCAGGACTTTAGGAGGCCAAGGTGGGAGGATTGTTTGAGCCCAGGAGTTCAAGACCAGCTTGAGCAATATAGTGAGACCCTGTCTCTACA
AAAACAAACAAACAAACAAACAAATAAATAAATAAATAAAATTAGCTGGGAATGGTGATGCACACCTGGAGTCCTAGCTACTCAGAAGGC
TGAGGCAGGACGATCACTTGACCTCAGAAGTCTGAGGTTACAGTGAGCTATGATCATACCAGTGCACTCCAGTCTGGGTGACAGAACAAG
ACCCTGTCTCCAAAAATTAAATAAATAAAACAAAAAAAAAGAATTTAAAAGTTTTATATAAAGGCATAGCTACTATCTCATCTGCCCAGT
GTAGTCATGAATAGATGTCACATAAAGAAAAGAAAACCAGAATTCTTGTTAATATGGCCAGTTTGAAGGGTGGTGGCGGAGGTATTGAGC
AGGCAGCTCAGGGAAATGCCAGGGAGACCCTTGAGCACAGAAACTCCTGATTGTCCCCAGGGACTCTCCGTGGACACAGGAGGGATTTTC
CAGGATTTCACATGAATTCAATGAAGGGGGCTGTGTCTTATTCCTGGATGCTTTGCCTCCTTCATGGAATTCAGTGGATTTAATGGAAGT
TCCTAGGCAACAATAAAGAGTAGAAACCAGGTTAACAGCGAGGGCCTCATCTCACACCAGATCATATCAGGCTACACAAAAGTAGATGGA
AGACACCACCCAGGCCTCCAGCTATACACTGGAGAAGAAGCCAAACTAGTCTACTTCATCTAAGAAAGTTGTCAAAGAGAGCCCTTCTAT
ACTATCTTAAGGTAAAAAGAAAGACTCTACCCAGCTGCCCTGATTAAGCATTAGAAAGATAAGTGTTCTGATCATTAGGCGAAAGACAAT
GGGGAAAAATGTAGAAAAGAAATATGACATGAGCCAGATGAAGAACCCATCCTGAAAGGATATATAACTCAGGGGACAAAAGACAACTCA
CCATAAGTTGGGCGCAGTGGATCACGCCTGTAATCTCAGCATTTTGGTAGGCCAAGGCAGGTGGATCACCTGAGGTCAGGAGTTCAAGTC
CAGCCTGGCCAACGTGGTGAAATCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGTGCATGCCTGTAATACCAGCTACTC
AGAAGGCTGAGGCAAGAGAATTGCTTGAATCAAGGAGGCAGAGGTTACAGTGAGCCAAGATCAGGCCATTGTACTTCAGCCTGGGCGACA
AAGTGAGACCCTGTCTCAAAAAACAAACAAAGCCTCCCCATAGATGTCTCCTGCCATAGAAGAATTTAAGAAGTTCATAAATTCAATAAA
ACAAGAGTTGAAGGCCTGTCCCACTGTACCCAATTTCTCCCTCTCTGAACTGCAGCCTAGAAACTCTCTACAGGCAGTAAGCTGGGGCAG
TCACAGAGGTGACCTCATCTGTTTCCCACATCCTGCATTAGGACAGTGATCAGGGATCAGTATCCTTCATTGACTGATTTCCAATATCTC
GAGACCTGTTGTTTCATATATTTTGCCTTATTTTGCAATTGTTTCATATATTTTGTCTTATTTTGCAATTGTTTCAGGAGGGAGGATAAA
TATGGTCCCTGTTCCTCTATCTTGACCAGAAGCATCTAAGAAGGCAGTGAAGCAACATGTGTACAGTTCTTAGGGAAACAAATTTTGACC
TAAAAATATTAAACCTAGTCAAAATATTATTCTAGTACAAAGGCAGCACATGGGTATTTTTGAACATAAAAGAGTTCTAGAAATACAGGA
CCCATGAATCATTCTTGAAGAAAAGTTACTCAGTAAGGAAATCTAGCTAAGCAAGCAACATGTACAAATAAAAGATTATTATAATTGGAC
CAAAGTTAAGTTTAAATCCATTCACATGTATATAATTAAGATATATAGGAATTATAATTACAGAAAAGAATGTTACAAACCTTCACAAAG
TAAAAATATTTTTATATCAGATAGATTCTTCTGTTTCAATCCATAAAACCAGGGTTTGGATCATTTTAAAAAAACAAACAAAAATAATTT
ATTGGAATCATTAGGGAGGACCTGATAGAATAAAATGACAAGCTGACCAAATAGGCCTTAGAAGGGAGAGGTGCCTGGGCAGTTACAAGG
ACCTAGGTAGCAGGGGTGACTTGGCCACAGTCATTTTCTTTACTTGATTTAAGGAGGTTAAATTACAGTGAGAGAGTTGCACTTATTTAG
TTTGCATACCGTACTCAACTCTTAGCTAGCATAGGGCAGGTTCCTTAGTTGAAAAATTTCCACAAAACATGATGTAAAGTGGAAAGATCA
GTTCCCCCAAAGAATATCAGTTACCAAAGTAGGATGAAAGGATGTTGGGTAGATCAAAACAACAAATGTCCATTACAGCAATTAACAAAA
GTTAGGGAGTGGGGAAGTCTGAGTGCTAATATGGATTTCAAAACAACTTTAAAAATGGCTTCAAACATTTTATGCTTTTTGTAATTTAGT
CATTTTAATATTAGATAAATCTTCCTGTAACTGAAAGTTCTTGAGTTAAAGAAAAATATTCGGTAGTTCAGCTCTTCCTTCAATTTTATT
AGTTGCTTTTTCTTTTGTTCAAGTGAAATAAACATAAAAATAATTTTAAAATATTATGTATCATATCCTTCGATTTAACATAATTCTATC
TAGCTGTTCTTATATTTTCTCTGATATATTTTTAAAAGCTTTCTGGAATATTATTAACCTTGAATATTTCTAGTTGATGAGTTTATGAGT
GATTTATTGCTTCCTTTTCTCTTTCAGTATTGCTAGAATTAATTTTATTGACTTTGCCCCTTTGCATAAAGACCTTGAAGGTCACATGCT
GAAATCGCCCTCTACTAAAACAAACTCATAGAAATAATGGGGAAGATATTTCAAAACATTGCCATATGCATAGCCATCCTCACAACCAAG
AAAAGCGCCTCTCCATGAACTAAAACCTATGAGTCATTGGTACAGGTAGGGAAAATCTAGGTAAACCACGGTAATACACTGAGGCTGGCA
CCACCACAGGCCAGGACAACCGTTGTCACAAAGCCAGGACAGAATCTCCCAGCCAGAAAGTGTTGCCCTGAGGCTGAAGCCAAATTCATT
TTGCCCCCAGTTGGCCAGACCAAAGCCTAGAACTAAAAAACCCATACCTCAGGGTTTGTCAGCATTGGCACTGCTGGCTTTTTGGGCTGG
ACAACCATTTATTGTGAGAGGCTTCTCTATGCACTGTAGGATGTTTAGCAGCATCCTTGGCCCTACTCCCTAGACGCCAGTAGCAAATCC
ACCACCCTCCCTCCCCTACCCCAGGGTTGGTTGTCAGTTGTGACAACCAAAAATGTCTCCAGACATCGCCAAATGTCCCTTGGGGGGTAA
AATCACCACCACCATACCTCTTTTGACTAAAAGAGTTTCCAGAATAGTGGCAGAATATATAGGTCAAGCATAACACATTACAATCAAGAT
TCAGAACATCAAAGATTCTTTTTTAATCCTAAAAGAAAAAGTTTGGAAAATCTACAAAAAGAAGTGTGAATTTGACAATAACTATTTCAC
TAGCAAGGGTAGACGTAAGCAGAATACAGGTAGCATATTCAAACTGCTGTGGAAAAACAACATCAAACCTAGACTTCTCTCCCCAAACTA
TCATTCAGAGTCGAGGGCAAAATAAATAGATTTTCTGACTTGGAACAAGTAGGAATAATGTACTTATAGTATTCATCTTCATACAGGGAT
GGACTATAAGTGATTTTTAAAAAACTTCCTACTTGTTCCAAGTCAGAAAAACTATTCATATAGGGATGGGCTATTAGCAAGAGTATATGA
ATAACGTACTATAACAAGAAAAAATGAATTGAGAAGAAAGTAGTGGTTTTAAGAAGGAAAGGAGAACAAATAAATTAGTGAAACATAAGG
TTAAGTCTATACATATTATTTTCTAATTGCCTATTATGTCAGACTACATGTAGTTAGAAAATACGATGAAAGAAAAAGCCATATTATAAT
TCCAACAAAAAGATAAAATAATTAAGAATAACTGCAACAAGAAAATATAAGTTCTGCAACAATAAAACTATACAATGAAACTAAAGAGCA
CAAAAAAGAACTTAAACAGATAAAAAGCAGACCACGTTTTTGGATAAGAAGATTAAAAATTATAAATATATCAATTTTCACTGTTAATCT
ATAAATTCAGTGTAATCCCAATAAAAATGCCAACAGGTTTTCCCCAATAGCATTGAAATGATTTTAAAATTTAATGAAGGCCAAGCATGG
TGGCTCACTCCTGTAATCCCAGCACTTTGAGAGGCCGAGGCAGGTGGATTGCCTGAGTCCAGGAGTTCCAGACCAGCCTGGACAACATGG
TGAAATCCCGTCTCTATTTAAAATGCAAGAAATTAGCTGGGTGTGGTGGTGTGCACCTATAGTCCTAGCTACTCGGGAGGCTGAGGTGGG
AGAATCACCCAAGCCTTGGGAGGTCGAGGCTGTAGTGAGCCAAAATCACATCACTGCACTCCAGTCTGGGCAGCCAGAGTGAGACCCTGT
CTCAAAAAAAAAAAAATTATTGGAAACTACGAGGCAAGAATATCCAAGAAAAATCTAGAAAAGAAGAAACCTGAGTGAGTCAGCATGACC
AAATATTAAAACATCTTATAAAGCTACAATAATTAAAACAATGTGGTGCTGATATGTGGAGGGTCAATGGAACAAGATGAAATGGCCAAA
AATAAATTTAAAATACATGTTGAAATGTATTAACAGCATATGTTAAAGTTAAGTTATGTTAACTTTATATGTTAAATTCAAGTTAATTGG
GGAAAGATGGATTATTCAATATATGATGAACAACTCTGTCACCCAGCTAAAAAAAATTAAGCTTGGGCCATATGCCAGACTAGATACCAA
AATAAATTCCAGGAGGACCAAGTTTTTAAAAGTAAAAATATGGAATCATGGAAGTGCATGAAGAAGAAGTAGCACTTAAAAAAATAATAA
TCTCAGCATGGGGAAGGTCTAAGTATGGCCCTCAATCAGAAACCAGGAAGGAAAATATTGACTATTTTAAACAAAATTATCTCTGTACCA
AAAACAGCATAAAAGGTCAAGAAACAACACACTGGAAAAAGAATTGCAATGAATATCACAGCCAAATAGTTAATTTCTTATTTTCAAAAA
ATAGCTTCTACAAATCGAAGAGAAAAATTCTAAGGTCTCAAAGGAAAAATGAGCAAAGGATTTGACAGGTGGTAGAATACAGAAAAAGAA
TTTAAAATAGCTCCTAAAGATATGGAAACATTACTCATGATAGCAGAAGTATCAATTGACAAAATTACTCAGATTGGTAACAAACTTTAA
GGGGGAAAGCACTTCCATGCATTGCTGTAAATTGGTACATCTTCTACTGAGAACAATCCGGCAGTAGTTAACAAAATTGTGAATGCATAT
ATCTCTTTCTCTAGAAATTTCTCTTTTGGGAATTTATTCTACATATATATTCAAACGTGTGAAATACTTCTATACAGGTGATTGAATTTC
ACTTTATTCCTAAGAGCAGAAGACTGCAAAATAGTAAATATATACCCAAAAGGGTCTAATGGATTAGTTTTTGGCATATCAGCACATGAT
AATACTATGAAGCCATAAAAAAGAGAGATCTCTATATGTATTGATGGGGGACCATCTTTAAGATATACTGTGGTGTTGAACAAAACAACA
TGCTGAAAATGTCTCTTATTCTTTTAGAATCAATATAAGTCTGTGCTTGTAAATGCAGTAAGTATCTTTGGAAGTATACCTAAAAATTGG
TAATAGTGTTTGACTCCAGGGAAGAACAGATGGGTGCCAGAGTGAAAAAAAGATAGCTTTTGCTTTTTATGACTTTTGGATTCTGTACCA
CGTAATAATTTTGATGTAAATTTTGCTGTGTGTGTTTTTACTTGTTCATGTAGTGATTTTATAAATTACTCTTTTAATTTTCTATCAATG
AATATCCTGGGATAAACCCCTCATGATCATAATGAATAATGATGTGTGGAGAGTGGGGAGGGTTTACATATGAAAAATGTAGAAAATACA
AAAAGTGTCTATATATACAAAAATGTAAGTGTTAACATTTTTATATTTGCTTCAAGCTTTTTTTTTAAATAAAAGAAATGCAATATTGCA

>79093_79093_1_SAMD4B-SLFN5_SAMD4B_chr19_39847729_ENST00000314471_SLFN5_chr17_33591202_ENST00000299977_length(amino acids)=577AA_BP=65
MMFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLESEANSAVFSDRVVYTPESLYKELFSQHKGLR
DLINTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMIVAYSLKQKLVNKGGYTGRLCITPLV
CVLNSDRKAQSVYSSYLQIYPESYNFMTPQHMEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGK
TILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQHIIIDDAQNFRTEDGDWYGKAKFITQTARD
GPGVLWIFLDYFQTYHLSCSGLPPPSDQYPREEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDL
NLEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDLLLQIGDASDVLTDHIVLDSVCRFSGLERN

--------------------------------------------------------------
>79093_79093_2_SAMD4B-SLFN5_SAMD4B_chr19_39847729_ENST00000596368_SLFN5_chr17_33591202_ENST00000299977_length(transcript)=9579nt_BP=274nt
GAGGCCAGAGCCGGGACCATGTGACGGCGCTGGCCCTCGCCACCGCCGTCCCCCGACCCTGGCCCCAGGCCCGGCACCATGATGTTCCGA
GACCAGGTGGGCATCCTCGCTGGCTGGTTCAAAGGCTGGAATGAGTGTGAGCAGACAGTGGCCCTCCTGTCACTTCTGAAACGGGTCACC
CGTACCCAGGCCCGCTTCCTGCAGCTCTGCCTGGAGCACTCACTGGCGGACTGCAATGACATCCACCTGCTGGAGTCGGAGGCCAACAGT
GCTGTATTTTCAGACAGAGTGGTATATACTCCAGAAAGCCTCTACAAGGAACTCTTCTCACAACATAAAGGACTCAGAGACTTAATAAAT
ACAGAAATGCGCCCTTTCTCTCAAGGAATATTGATTTTTTCTCAAAGCTGGGCTGTGGATTTAGGTCTGCAAGAGAAGCAGGGAGTCATC
TGTGATGCTCTTCTAATTTCCCAGAACAACACCCCTATTCTCTACACCATCTTCAGCAAGTGGGATGCGGGGTGCAAGGGCTATTCTATG
ATAGTTGCCTATTCTTTGAAGCAGAAGCTGGTGAACAAAGGCGGCTACACTGGGAGGTTATGCATCACCCCCTTGGTCTGTGTGCTGAAT
TCTGATAGAAAAGCACAGAGCGTTTACAGTTCGTATTTACAAATTTACCCTGAATCCTATAACTTCATGACCCCCCAGCACATGGAAGCC
CTGTTACAGTCCCTCGTGATAGTCTTGCTTGGGTTCAAATCCTTCTTAAGTGAAGAGCTGGGCTCTGAGGTTTTGAACCTACTGACAAAT
AAACAGTATGAGTTGCTTTCAAAGAACCTTCGCAAGACCAGAGAGTTGTTTGTTCATGGCTTACCTGGATCAGGGAAGACTATCTTGGCT
CTTAGGATCATGGAGAAGATCAGGAATGTGTTTCACTGTGAACCGGCTAACATTCTCTACATCTGTGAAAACCAGCCCCTGAAGAAGTTG
GTGAGTTTCAGCAAGAAAAACATCTGCCAGCCAGTGACCCGGAAAACCTTCATGAAAAACAACTTTGAACACATCCAGCACATTATCATT
GATGACGCTCAGAATTTCCGTACTGAAGATGGGGACTGGTATGGGAAAGCAAAGTTCATCACTCAGACAGCAAGGGATGGCCCAGGAGTT
CTCTGGATCTTTCTGGACTACTTTCAGACCTATCACTTGAGTTGCAGTGGCCTCCCCCCTCCCTCAGACCAGTATCCAAGAGAAGAGATC
AACAGAGTGGTCCGCAATGCAGGTCCAATAGCTAATTACCTACAACAAGTAATGCAGGAAGCCCGACAAAATCCTCCACCTAACCTCCCC
CCTGGGTCCCTGGTGATGCTCTATGAACCTAAATGGGCTCAAGGTGTCCCAGGCAACTTAGAGATTATTGAAGACTTGAACTTGGAGGAG
ATACTGATCTATGTAGCGAATAAATGCCGTTTTCTCTTGCGGAATGGTTATTCTCCGAAGGATATTGCTGTGCTTTTCACCAAAGCAAGT
GAAGTGGAAAAATATAAAGACAGGCTTCTAACAGCAATGAGGAAGAGAAAACTGTCTCAGCTCCATGAGGAGTCTGATCTGTTACTACAG
ATCGGTGATGCGTCGGATGTTCTAACCGATCACATTGTGTTGGACAGTGTCTGTCGATTTTCAGGCCTGGAAAGAAATATCGTGTTTGGA
ATCAATCCAGGAGTAGCCCCACCGGCTGGGGCCTACAATCTTCTGCTCTGTTTGGCTTCTAGGGCAAAAAGACATCTGTATATTCTGAAG
GCTTCTGTGTGACAGGAAACCCAAGCCTAAGAAACAATTAAGTGGTTCTCATCTCTAATTAACTGTGAAACCATTTAATCCAAACATGTA
AGCACACACTCACTTATTAAGTCACATACTTTTCTAGGTGCTGGGGATTGAGAACGAATCGATGTAAGATTCCTCCTTTAGGGCAGAGAC
AGACCACTGACAAATACACAGATAGACAAGGAATTTCCCATGGTAAAAAGGGATATCAGTAATTAGAGGACCGTGAGACTCAGAGATGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCACGTGCACATGTGTGTAGGTAGATGGAGGGGGTGATTATTTTGGGTGGT
CAGGGAAGTGCTCAGTGAGGGAAGAACTTGTCATGAGAATCTCTGAGCGTGCCAGGCAGACTCGGATATTTTTATAAATTTTTAACATGG
CCACTTGCAGAAGAGCTTGAATGGGACGTGCAGCGAGAATGTGAAGGATGGAGCAGGTAGCTCATCTGGCCTTGTAGGTGCCGGGAACGG
GCAAGACATGTTTTGAAATGTAAGATCACAGACTGTTTTTTGCAAGACCACATTATATTACTTTATTATTTTCTGCTTTTTCTTTTAACG
ACATTAGTGTTTTTGATCACTATATTTTAAAATGCTTTTTGTGAGCCTTTTGGTTATGTGGAATCTGTTCCTTAGCTCTGATTTTTTATT
CTTATGGAGCGTCTTAGGTTACTACATGAAGGTAAGACTGCCACAGTCCCCCAGGGAGGCACACTGTGTTTTACTGATTGATTTGAAGAT
GATAGAGAGCCTAGGGGGATGAGTCTATTGGACTCAAAGGTTACATTTTGTTTTTCCATTTAATTTAATAATCAACAAAACGACAAAGTC
AGTTTAATATCTTTCTTCTGCTGAGTCTTCAGGATGTTAGCTAGTCTTTCAAAAGCCATTGCTACAAAAGTGCAAATTTCTCATTTCCTG
TGGGTCTCTAGAAACTCTCTCAATATTTAAAGCCAAACAAATCCATCTTTTCTGAGAGACAGAAACTAAAAAATTCAGAGTTAATTCACT
ATTAAAAACAGCAAGGCCCTGCTATTTCCCAAGAATAAAGAAATTTAAAATTCTCATTGTAAGAAGTATGAACTTGAAGCTAGAATTGGT
TTATTTCTGGCAGCTACTTACAATATTAAGAACTTTACTTTTTAAATTTGAGACAATTTCACAGGAAAGCAAGAAATTAGTCTATTGTGA
AATGTTTTTACAACTAACTTGGAATATACTGCAAATCACTAGTAAGTAGAGACACATTTAAGATAAAATGATTAATAAAACAATTGGTAA
TTCTGAATAAGGATCTGAATAAATCCAGATCACAGACTGTTCCTTTACCAATATGTAAAAGAATGTGCAAAATTAGTAAAAATATACCCA
AAAATTTACCAGCAACAGAGAAGCAAAGAATGGAGTTCAACCTTACACTATAAACATCTAATAGATATGTATGAAAATTTAAAAACTAGA
AAAGGTTGGGCATGGTGGCTCATGCTTGTGATCCCAGGACTTTAGGAGGCCAAGGTGGGAGGATTGTTTGAGCCCAGGAGTTCAAGACCA
GCTTGAGCAATATAGTGAGACCCTGTCTCTACAAAAACAAACAAACAAACAAACAAATAAATAAATAAATAAAATTAGCTGGGAATGGTG
ATGCACACCTGGAGTCCTAGCTACTCAGAAGGCTGAGGCAGGACGATCACTTGACCTCAGAAGTCTGAGGTTACAGTGAGCTATGATCAT
ACCAGTGCACTCCAGTCTGGGTGACAGAACAAGACCCTGTCTCCAAAAATTAAATAAATAAAACAAAAAAAAAGAATTTAAAAGTTTTAT
ATAAAGGCATAGCTACTATCTCATCTGCCCAGTGTAGTCATGAATAGATGTCACATAAAGAAAAGAAAACCAGAATTCTTGTTAATATGG
CCAGTTTGAAGGGTGGTGGCGGAGGTATTGAGCAGGCAGCTCAGGGAAATGCCAGGGAGACCCTTGAGCACAGAAACTCCTGATTGTCCC
CAGGGACTCTCCGTGGACACAGGAGGGATTTTCCAGGATTTCACATGAATTCAATGAAGGGGGCTGTGTCTTATTCCTGGATGCTTTGCC
TCCTTCATGGAATTCAGTGGATTTAATGGAAGTTCCTAGGCAACAATAAAGAGTAGAAACCAGGTTAACAGCGAGGGCCTCATCTCACAC
CAGATCATATCAGGCTACACAAAAGTAGATGGAAGACACCACCCAGGCCTCCAGCTATACACTGGAGAAGAAGCCAAACTAGTCTACTTC
ATCTAAGAAAGTTGTCAAAGAGAGCCCTTCTATACTATCTTAAGGTAAAAAGAAAGACTCTACCCAGCTGCCCTGATTAAGCATTAGAAA
GATAAGTGTTCTGATCATTAGGCGAAAGACAATGGGGAAAAATGTAGAAAAGAAATATGACATGAGCCAGATGAAGAACCCATCCTGAAA
GGATATATAACTCAGGGGACAAAAGACAACTCACCATAAGTTGGGCGCAGTGGATCACGCCTGTAATCTCAGCATTTTGGTAGGCCAAGG
CAGGTGGATCACCTGAGGTCAGGAGTTCAAGTCCAGCCTGGCCAACGTGGTGAAATCCTGTCTCTACTAAAAATACAAAAATTAGCTGGG
TGTGGTGGTGCATGCCTGTAATACCAGCTACTCAGAAGGCTGAGGCAAGAGAATTGCTTGAATCAAGGAGGCAGAGGTTACAGTGAGCCA
AGATCAGGCCATTGTACTTCAGCCTGGGCGACAAAGTGAGACCCTGTCTCAAAAAACAAACAAAGCCTCCCCATAGATGTCTCCTGCCAT
AGAAGAATTTAAGAAGTTCATAAATTCAATAAAACAAGAGTTGAAGGCCTGTCCCACTGTACCCAATTTCTCCCTCTCTGAACTGCAGCC
TAGAAACTCTCTACAGGCAGTAAGCTGGGGCAGTCACAGAGGTGACCTCATCTGTTTCCCACATCCTGCATTAGGACAGTGATCAGGGAT
CAGTATCCTTCATTGACTGATTTCCAATATCTCGAGACCTGTTGTTTCATATATTTTGCCTTATTTTGCAATTGTTTCATATATTTTGTC
TTATTTTGCAATTGTTTCAGGAGGGAGGATAAATATGGTCCCTGTTCCTCTATCTTGACCAGAAGCATCTAAGAAGGCAGTGAAGCAACA
TGTGTACAGTTCTTAGGGAAACAAATTTTGACCTAAAAATATTAAACCTAGTCAAAATATTATTCTAGTACAAAGGCAGCACATGGGTAT
TTTTGAACATAAAAGAGTTCTAGAAATACAGGACCCATGAATCATTCTTGAAGAAAAGTTACTCAGTAAGGAAATCTAGCTAAGCAAGCA
ACATGTACAAATAAAAGATTATTATAATTGGACCAAAGTTAAGTTTAAATCCATTCACATGTATATAATTAAGATATATAGGAATTATAA
TTACAGAAAAGAATGTTACAAACCTTCACAAAGTAAAAATATTTTTATATCAGATAGATTCTTCTGTTTCAATCCATAAAACCAGGGTTT
GGATCATTTTAAAAAAACAAACAAAAATAATTTATTGGAATCATTAGGGAGGACCTGATAGAATAAAATGACAAGCTGACCAAATAGGCC
TTAGAAGGGAGAGGTGCCTGGGCAGTTACAAGGACCTAGGTAGCAGGGGTGACTTGGCCACAGTCATTTTCTTTACTTGATTTAAGGAGG
TTAAATTACAGTGAGAGAGTTGCACTTATTTAGTTTGCATACCGTACTCAACTCTTAGCTAGCATAGGGCAGGTTCCTTAGTTGAAAAAT
TTCCACAAAACATGATGTAAAGTGGAAAGATCAGTTCCCCCAAAGAATATCAGTTACCAAAGTAGGATGAAAGGATGTTGGGTAGATCAA
AACAACAAATGTCCATTACAGCAATTAACAAAAGTTAGGGAGTGGGGAAGTCTGAGTGCTAATATGGATTTCAAAACAACTTTAAAAATG
GCTTCAAACATTTTATGCTTTTTGTAATTTAGTCATTTTAATATTAGATAAATCTTCCTGTAACTGAAAGTTCTTGAGTTAAAGAAAAAT
ATTCGGTAGTTCAGCTCTTCCTTCAATTTTATTAGTTGCTTTTTCTTTTGTTCAAGTGAAATAAACATAAAAATAATTTTAAAATATTAT
GTATCATATCCTTCGATTTAACATAATTCTATCTAGCTGTTCTTATATTTTCTCTGATATATTTTTAAAAGCTTTCTGGAATATTATTAA
CCTTGAATATTTCTAGTTGATGAGTTTATGAGTGATTTATTGCTTCCTTTTCTCTTTCAGTATTGCTAGAATTAATTTTATTGACTTTGC
CCCTTTGCATAAAGACCTTGAAGGTCACATGCTGAAATCGCCCTCTACTAAAACAAACTCATAGAAATAATGGGGAAGATATTTCAAAAC
ATTGCCATATGCATAGCCATCCTCACAACCAAGAAAAGCGCCTCTCCATGAACTAAAACCTATGAGTCATTGGTACAGGTAGGGAAAATC
TAGGTAAACCACGGTAATACACTGAGGCTGGCACCACCACAGGCCAGGACAACCGTTGTCACAAAGCCAGGACAGAATCTCCCAGCCAGA
AAGTGTTGCCCTGAGGCTGAAGCCAAATTCATTTTGCCCCCAGTTGGCCAGACCAAAGCCTAGAACTAAAAAACCCATACCTCAGGGTTT
GTCAGCATTGGCACTGCTGGCTTTTTGGGCTGGACAACCATTTATTGTGAGAGGCTTCTCTATGCACTGTAGGATGTTTAGCAGCATCCT
TGGCCCTACTCCCTAGACGCCAGTAGCAAATCCACCACCCTCCCTCCCCTACCCCAGGGTTGGTTGTCAGTTGTGACAACCAAAAATGTC
TCCAGACATCGCCAAATGTCCCTTGGGGGGTAAAATCACCACCACCATACCTCTTTTGACTAAAAGAGTTTCCAGAATAGTGGCAGAATA
TATAGGTCAAGCATAACACATTACAATCAAGATTCAGAACATCAAAGATTCTTTTTTAATCCTAAAAGAAAAAGTTTGGAAAATCTACAA
AAAGAAGTGTGAATTTGACAATAACTATTTCACTAGCAAGGGTAGACGTAAGCAGAATACAGGTAGCATATTCAAACTGCTGTGGAAAAA
CAACATCAAACCTAGACTTCTCTCCCCAAACTATCATTCAGAGTCGAGGGCAAAATAAATAGATTTTCTGACTTGGAACAAGTAGGAATA
ATGTACTTATAGTATTCATCTTCATACAGGGATGGACTATAAGTGATTTTTAAAAAACTTCCTACTTGTTCCAAGTCAGAAAAACTATTC
ATATAGGGATGGGCTATTAGCAAGAGTATATGAATAACGTACTATAACAAGAAAAAATGAATTGAGAAGAAAGTAGTGGTTTTAAGAAGG
AAAGGAGAACAAATAAATTAGTGAAACATAAGGTTAAGTCTATACATATTATTTTCTAATTGCCTATTATGTCAGACTACATGTAGTTAG
AAAATACGATGAAAGAAAAAGCCATATTATAATTCCAACAAAAAGATAAAATAATTAAGAATAACTGCAACAAGAAAATATAAGTTCTGC
AACAATAAAACTATACAATGAAACTAAAGAGCACAAAAAAGAACTTAAACAGATAAAAAGCAGACCACGTTTTTGGATAAGAAGATTAAA
AATTATAAATATATCAATTTTCACTGTTAATCTATAAATTCAGTGTAATCCCAATAAAAATGCCAACAGGTTTTCCCCAATAGCATTGAA
ATGATTTTAAAATTTAATGAAGGCCAAGCATGGTGGCTCACTCCTGTAATCCCAGCACTTTGAGAGGCCGAGGCAGGTGGATTGCCTGAG
TCCAGGAGTTCCAGACCAGCCTGGACAACATGGTGAAATCCCGTCTCTATTTAAAATGCAAGAAATTAGCTGGGTGTGGTGGTGTGCACC
TATAGTCCTAGCTACTCGGGAGGCTGAGGTGGGAGAATCACCCAAGCCTTGGGAGGTCGAGGCTGTAGTGAGCCAAAATCACATCACTGC
ACTCCAGTCTGGGCAGCCAGAGTGAGACCCTGTCTCAAAAAAAAAAAAATTATTGGAAACTACGAGGCAAGAATATCCAAGAAAAATCTA
GAAAAGAAGAAACCTGAGTGAGTCAGCATGACCAAATATTAAAACATCTTATAAAGCTACAATAATTAAAACAATGTGGTGCTGATATGT
GGAGGGTCAATGGAACAAGATGAAATGGCCAAAAATAAATTTAAAATACATGTTGAAATGTATTAACAGCATATGTTAAAGTTAAGTTAT
GTTAACTTTATATGTTAAATTCAAGTTAATTGGGGAAAGATGGATTATTCAATATATGATGAACAACTCTGTCACCCAGCTAAAAAAAAT
TAAGCTTGGGCCATATGCCAGACTAGATACCAAAATAAATTCCAGGAGGACCAAGTTTTTAAAAGTAAAAATATGGAATCATGGAAGTGC
ATGAAGAAGAAGTAGCACTTAAAAAAATAATAATCTCAGCATGGGGAAGGTCTAAGTATGGCCCTCAATCAGAAACCAGGAAGGAAAATA
TTGACTATTTTAAACAAAATTATCTCTGTACCAAAAACAGCATAAAAGGTCAAGAAACAACACACTGGAAAAAGAATTGCAATGAATATC
ACAGCCAAATAGTTAATTTCTTATTTTCAAAAAATAGCTTCTACAAATCGAAGAGAAAAATTCTAAGGTCTCAAAGGAAAAATGAGCAAA
GGATTTGACAGGTGGTAGAATACAGAAAAAGAATTTAAAATAGCTCCTAAAGATATGGAAACATTACTCATGATAGCAGAAGTATCAATT
GACAAAATTACTCAGATTGGTAACAAACTTTAAGGGGGAAAGCACTTCCATGCATTGCTGTAAATTGGTACATCTTCTACTGAGAACAAT
CCGGCAGTAGTTAACAAAATTGTGAATGCATATATCTCTTTCTCTAGAAATTTCTCTTTTGGGAATTTATTCTACATATATATTCAAACG
TGTGAAATACTTCTATACAGGTGATTGAATTTCACTTTATTCCTAAGAGCAGAAGACTGCAAAATAGTAAATATATACCCAAAAGGGTCT
AATGGATTAGTTTTTGGCATATCAGCACATGATAATACTATGAAGCCATAAAAAAGAGAGATCTCTATATGTATTGATGGGGGACCATCT
TTAAGATATACTGTGGTGTTGAACAAAACAACATGCTGAAAATGTCTCTTATTCTTTTAGAATCAATATAAGTCTGTGCTTGTAAATGCA
GTAAGTATCTTTGGAAGTATACCTAAAAATTGGTAATAGTGTTTGACTCCAGGGAAGAACAGATGGGTGCCAGAGTGAAAAAAAGATAGC
TTTTGCTTTTTATGACTTTTGGATTCTGTACCACGTAATAATTTTGATGTAAATTTTGCTGTGTGTGTTTTTACTTGTTCATGTAGTGAT
TTTATAAATTACTCTTTTAATTTTCTATCAATGAATATCCTGGGATAAACCCCTCATGATCATAATGAATAATGATGTGTGGAGAGTGGG
GAGGGTTTACATATGAAAAATGTAGAAAATACAAAAAGTGTCTATATATACAAAAATGTAAGTGTTAACATTTTTATATTTGCTTCAAGC

>79093_79093_2_SAMD4B-SLFN5_SAMD4B_chr19_39847729_ENST00000596368_SLFN5_chr17_33591202_ENST00000299977_length(amino acids)=577AA_BP=65
MMFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLESEANSAVFSDRVVYTPESLYKELFSQHKGLR
DLINTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMIVAYSLKQKLVNKGGYTGRLCITPLV
CVLNSDRKAQSVYSSYLQIYPESYNFMTPQHMEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGK
TILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQHIIIDDAQNFRTEDGDWYGKAKFITQTARD
GPGVLWIFLDYFQTYHLSCSGLPPPSDQYPREEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDL
NLEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDLLLQIGDASDVLTDHIVLDSVCRFSGLERN

--------------------------------------------------------------
>79093_79093_3_SAMD4B-SLFN5_SAMD4B_chr19_39847729_ENST00000598913_SLFN5_chr17_33591202_ENST00000299977_length(transcript)=9841nt_BP=536nt
ACGGCGGCGGCGGCGGCGGCGGCGGTGGTCGGTGCGGGAGGAGGGAGGGGAGCTTGCGGGCCCGAGAGGGGGCGACGGCGGCGGCGGTGG
CCTGAGGAGGCCCGAGCGGCGGCGGTGGCGGCGAAGGCCGAGGCGGAAACTGGAGAGGCGTGGCTGGACCAAGACCTCCCCCCATGTGAG
CAGGCTTCCTCCTCCCCCAACAACCGTTGCCACCACGCCCAGAAACGTCCTTAAGCCCTGGCCCTCAGGGGAAAGGTAACAGGAGGCCAG
AGCCGGGACCATGTGACGGCGCTGGCCCTCGCCACCGCCGTCCCCCGACCCTGGCCCCAGGCCCGGCACCATGATGTTCCGAGACCAGGT
GGGCATCCTCGCTGGCTGGTTCAAAGGCTGGAATGAGTGTGAGCAGACAGTGGCCCTCCTGTCACTTCTGAAACGGGTCACCCGTACCCA
GGCCCGCTTCCTGCAGCTCTGCCTGGAGCACTCACTGGCGGACTGCAATGACATCCACCTGCTGGAGTCGGAGGCCAACAGTGCTGTATT
TTCAGACAGAGTGGTATATACTCCAGAAAGCCTCTACAAGGAACTCTTCTCACAACATAAAGGACTCAGAGACTTAATAAATACAGAAAT
GCGCCCTTTCTCTCAAGGAATATTGATTTTTTCTCAAAGCTGGGCTGTGGATTTAGGTCTGCAAGAGAAGCAGGGAGTCATCTGTGATGC
TCTTCTAATTTCCCAGAACAACACCCCTATTCTCTACACCATCTTCAGCAAGTGGGATGCGGGGTGCAAGGGCTATTCTATGATAGTTGC
CTATTCTTTGAAGCAGAAGCTGGTGAACAAAGGCGGCTACACTGGGAGGTTATGCATCACCCCCTTGGTCTGTGTGCTGAATTCTGATAG
AAAAGCACAGAGCGTTTACAGTTCGTATTTACAAATTTACCCTGAATCCTATAACTTCATGACCCCCCAGCACATGGAAGCCCTGTTACA
GTCCCTCGTGATAGTCTTGCTTGGGTTCAAATCCTTCTTAAGTGAAGAGCTGGGCTCTGAGGTTTTGAACCTACTGACAAATAAACAGTA
TGAGTTGCTTTCAAAGAACCTTCGCAAGACCAGAGAGTTGTTTGTTCATGGCTTACCTGGATCAGGGAAGACTATCTTGGCTCTTAGGAT
CATGGAGAAGATCAGGAATGTGTTTCACTGTGAACCGGCTAACATTCTCTACATCTGTGAAAACCAGCCCCTGAAGAAGTTGGTGAGTTT
CAGCAAGAAAAACATCTGCCAGCCAGTGACCCGGAAAACCTTCATGAAAAACAACTTTGAACACATCCAGCACATTATCATTGATGACGC
TCAGAATTTCCGTACTGAAGATGGGGACTGGTATGGGAAAGCAAAGTTCATCACTCAGACAGCAAGGGATGGCCCAGGAGTTCTCTGGAT
CTTTCTGGACTACTTTCAGACCTATCACTTGAGTTGCAGTGGCCTCCCCCCTCCCTCAGACCAGTATCCAAGAGAAGAGATCAACAGAGT
GGTCCGCAATGCAGGTCCAATAGCTAATTACCTACAACAAGTAATGCAGGAAGCCCGACAAAATCCTCCACCTAACCTCCCCCCTGGGTC
CCTGGTGATGCTCTATGAACCTAAATGGGCTCAAGGTGTCCCAGGCAACTTAGAGATTATTGAAGACTTGAACTTGGAGGAGATACTGAT
CTATGTAGCGAATAAATGCCGTTTTCTCTTGCGGAATGGTTATTCTCCGAAGGATATTGCTGTGCTTTTCACCAAAGCAAGTGAAGTGGA
AAAATATAAAGACAGGCTTCTAACAGCAATGAGGAAGAGAAAACTGTCTCAGCTCCATGAGGAGTCTGATCTGTTACTACAGATCGGTGA
TGCGTCGGATGTTCTAACCGATCACATTGTGTTGGACAGTGTCTGTCGATTTTCAGGCCTGGAAAGAAATATCGTGTTTGGAATCAATCC
AGGAGTAGCCCCACCGGCTGGGGCCTACAATCTTCTGCTCTGTTTGGCTTCTAGGGCAAAAAGACATCTGTATATTCTGAAGGCTTCTGT
GTGACAGGAAACCCAAGCCTAAGAAACAATTAAGTGGTTCTCATCTCTAATTAACTGTGAAACCATTTAATCCAAACATGTAAGCACACA
CTCACTTATTAAGTCACATACTTTTCTAGGTGCTGGGGATTGAGAACGAATCGATGTAAGATTCCTCCTTTAGGGCAGAGACAGACCACT
GACAAATACACAGATAGACAAGGAATTTCCCATGGTAAAAAGGGATATCAGTAATTAGAGGACCGTGAGACTCAGAGATGTGTGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCACGTGCACATGTGTGTAGGTAGATGGAGGGGGTGATTATTTTGGGTGGTCAGGGAAG
TGCTCAGTGAGGGAAGAACTTGTCATGAGAATCTCTGAGCGTGCCAGGCAGACTCGGATATTTTTATAAATTTTTAACATGGCCACTTGC
AGAAGAGCTTGAATGGGACGTGCAGCGAGAATGTGAAGGATGGAGCAGGTAGCTCATCTGGCCTTGTAGGTGCCGGGAACGGGCAAGACA
TGTTTTGAAATGTAAGATCACAGACTGTTTTTTGCAAGACCACATTATATTACTTTATTATTTTCTGCTTTTTCTTTTAACGACATTAGT
GTTTTTGATCACTATATTTTAAAATGCTTTTTGTGAGCCTTTTGGTTATGTGGAATCTGTTCCTTAGCTCTGATTTTTTATTCTTATGGA
GCGTCTTAGGTTACTACATGAAGGTAAGACTGCCACAGTCCCCCAGGGAGGCACACTGTGTTTTACTGATTGATTTGAAGATGATAGAGA
GCCTAGGGGGATGAGTCTATTGGACTCAAAGGTTACATTTTGTTTTTCCATTTAATTTAATAATCAACAAAACGACAAAGTCAGTTTAAT
ATCTTTCTTCTGCTGAGTCTTCAGGATGTTAGCTAGTCTTTCAAAAGCCATTGCTACAAAAGTGCAAATTTCTCATTTCCTGTGGGTCTC
TAGAAACTCTCTCAATATTTAAAGCCAAACAAATCCATCTTTTCTGAGAGACAGAAACTAAAAAATTCAGAGTTAATTCACTATTAAAAA
CAGCAAGGCCCTGCTATTTCCCAAGAATAAAGAAATTTAAAATTCTCATTGTAAGAAGTATGAACTTGAAGCTAGAATTGGTTTATTTCT
GGCAGCTACTTACAATATTAAGAACTTTACTTTTTAAATTTGAGACAATTTCACAGGAAAGCAAGAAATTAGTCTATTGTGAAATGTTTT
TACAACTAACTTGGAATATACTGCAAATCACTAGTAAGTAGAGACACATTTAAGATAAAATGATTAATAAAACAATTGGTAATTCTGAAT
AAGGATCTGAATAAATCCAGATCACAGACTGTTCCTTTACCAATATGTAAAAGAATGTGCAAAATTAGTAAAAATATACCCAAAAATTTA
CCAGCAACAGAGAAGCAAAGAATGGAGTTCAACCTTACACTATAAACATCTAATAGATATGTATGAAAATTTAAAAACTAGAAAAGGTTG
GGCATGGTGGCTCATGCTTGTGATCCCAGGACTTTAGGAGGCCAAGGTGGGAGGATTGTTTGAGCCCAGGAGTTCAAGACCAGCTTGAGC
AATATAGTGAGACCCTGTCTCTACAAAAACAAACAAACAAACAAACAAATAAATAAATAAATAAAATTAGCTGGGAATGGTGATGCACAC
CTGGAGTCCTAGCTACTCAGAAGGCTGAGGCAGGACGATCACTTGACCTCAGAAGTCTGAGGTTACAGTGAGCTATGATCATACCAGTGC
ACTCCAGTCTGGGTGACAGAACAAGACCCTGTCTCCAAAAATTAAATAAATAAAACAAAAAAAAAGAATTTAAAAGTTTTATATAAAGGC
ATAGCTACTATCTCATCTGCCCAGTGTAGTCATGAATAGATGTCACATAAAGAAAAGAAAACCAGAATTCTTGTTAATATGGCCAGTTTG
AAGGGTGGTGGCGGAGGTATTGAGCAGGCAGCTCAGGGAAATGCCAGGGAGACCCTTGAGCACAGAAACTCCTGATTGTCCCCAGGGACT
CTCCGTGGACACAGGAGGGATTTTCCAGGATTTCACATGAATTCAATGAAGGGGGCTGTGTCTTATTCCTGGATGCTTTGCCTCCTTCAT
GGAATTCAGTGGATTTAATGGAAGTTCCTAGGCAACAATAAAGAGTAGAAACCAGGTTAACAGCGAGGGCCTCATCTCACACCAGATCAT
ATCAGGCTACACAAAAGTAGATGGAAGACACCACCCAGGCCTCCAGCTATACACTGGAGAAGAAGCCAAACTAGTCTACTTCATCTAAGA
AAGTTGTCAAAGAGAGCCCTTCTATACTATCTTAAGGTAAAAAGAAAGACTCTACCCAGCTGCCCTGATTAAGCATTAGAAAGATAAGTG
TTCTGATCATTAGGCGAAAGACAATGGGGAAAAATGTAGAAAAGAAATATGACATGAGCCAGATGAAGAACCCATCCTGAAAGGATATAT
AACTCAGGGGACAAAAGACAACTCACCATAAGTTGGGCGCAGTGGATCACGCCTGTAATCTCAGCATTTTGGTAGGCCAAGGCAGGTGGA
TCACCTGAGGTCAGGAGTTCAAGTCCAGCCTGGCCAACGTGGTGAAATCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGG
TGCATGCCTGTAATACCAGCTACTCAGAAGGCTGAGGCAAGAGAATTGCTTGAATCAAGGAGGCAGAGGTTACAGTGAGCCAAGATCAGG
CCATTGTACTTCAGCCTGGGCGACAAAGTGAGACCCTGTCTCAAAAAACAAACAAAGCCTCCCCATAGATGTCTCCTGCCATAGAAGAAT
TTAAGAAGTTCATAAATTCAATAAAACAAGAGTTGAAGGCCTGTCCCACTGTACCCAATTTCTCCCTCTCTGAACTGCAGCCTAGAAACT
CTCTACAGGCAGTAAGCTGGGGCAGTCACAGAGGTGACCTCATCTGTTTCCCACATCCTGCATTAGGACAGTGATCAGGGATCAGTATCC
TTCATTGACTGATTTCCAATATCTCGAGACCTGTTGTTTCATATATTTTGCCTTATTTTGCAATTGTTTCATATATTTTGTCTTATTTTG
CAATTGTTTCAGGAGGGAGGATAAATATGGTCCCTGTTCCTCTATCTTGACCAGAAGCATCTAAGAAGGCAGTGAAGCAACATGTGTACA
GTTCTTAGGGAAACAAATTTTGACCTAAAAATATTAAACCTAGTCAAAATATTATTCTAGTACAAAGGCAGCACATGGGTATTTTTGAAC
ATAAAAGAGTTCTAGAAATACAGGACCCATGAATCATTCTTGAAGAAAAGTTACTCAGTAAGGAAATCTAGCTAAGCAAGCAACATGTAC
AAATAAAAGATTATTATAATTGGACCAAAGTTAAGTTTAAATCCATTCACATGTATATAATTAAGATATATAGGAATTATAATTACAGAA
AAGAATGTTACAAACCTTCACAAAGTAAAAATATTTTTATATCAGATAGATTCTTCTGTTTCAATCCATAAAACCAGGGTTTGGATCATT
TTAAAAAAACAAACAAAAATAATTTATTGGAATCATTAGGGAGGACCTGATAGAATAAAATGACAAGCTGACCAAATAGGCCTTAGAAGG
GAGAGGTGCCTGGGCAGTTACAAGGACCTAGGTAGCAGGGGTGACTTGGCCACAGTCATTTTCTTTACTTGATTTAAGGAGGTTAAATTA
CAGTGAGAGAGTTGCACTTATTTAGTTTGCATACCGTACTCAACTCTTAGCTAGCATAGGGCAGGTTCCTTAGTTGAAAAATTTCCACAA
AACATGATGTAAAGTGGAAAGATCAGTTCCCCCAAAGAATATCAGTTACCAAAGTAGGATGAAAGGATGTTGGGTAGATCAAAACAACAA
ATGTCCATTACAGCAATTAACAAAAGTTAGGGAGTGGGGAAGTCTGAGTGCTAATATGGATTTCAAAACAACTTTAAAAATGGCTTCAAA
CATTTTATGCTTTTTGTAATTTAGTCATTTTAATATTAGATAAATCTTCCTGTAACTGAAAGTTCTTGAGTTAAAGAAAAATATTCGGTA
GTTCAGCTCTTCCTTCAATTTTATTAGTTGCTTTTTCTTTTGTTCAAGTGAAATAAACATAAAAATAATTTTAAAATATTATGTATCATA
TCCTTCGATTTAACATAATTCTATCTAGCTGTTCTTATATTTTCTCTGATATATTTTTAAAAGCTTTCTGGAATATTATTAACCTTGAAT
ATTTCTAGTTGATGAGTTTATGAGTGATTTATTGCTTCCTTTTCTCTTTCAGTATTGCTAGAATTAATTTTATTGACTTTGCCCCTTTGC
ATAAAGACCTTGAAGGTCACATGCTGAAATCGCCCTCTACTAAAACAAACTCATAGAAATAATGGGGAAGATATTTCAAAACATTGCCAT
ATGCATAGCCATCCTCACAACCAAGAAAAGCGCCTCTCCATGAACTAAAACCTATGAGTCATTGGTACAGGTAGGGAAAATCTAGGTAAA
CCACGGTAATACACTGAGGCTGGCACCACCACAGGCCAGGACAACCGTTGTCACAAAGCCAGGACAGAATCTCCCAGCCAGAAAGTGTTG
CCCTGAGGCTGAAGCCAAATTCATTTTGCCCCCAGTTGGCCAGACCAAAGCCTAGAACTAAAAAACCCATACCTCAGGGTTTGTCAGCAT
TGGCACTGCTGGCTTTTTGGGCTGGACAACCATTTATTGTGAGAGGCTTCTCTATGCACTGTAGGATGTTTAGCAGCATCCTTGGCCCTA
CTCCCTAGACGCCAGTAGCAAATCCACCACCCTCCCTCCCCTACCCCAGGGTTGGTTGTCAGTTGTGACAACCAAAAATGTCTCCAGACA
TCGCCAAATGTCCCTTGGGGGGTAAAATCACCACCACCATACCTCTTTTGACTAAAAGAGTTTCCAGAATAGTGGCAGAATATATAGGTC
AAGCATAACACATTACAATCAAGATTCAGAACATCAAAGATTCTTTTTTAATCCTAAAAGAAAAAGTTTGGAAAATCTACAAAAAGAAGT
GTGAATTTGACAATAACTATTTCACTAGCAAGGGTAGACGTAAGCAGAATACAGGTAGCATATTCAAACTGCTGTGGAAAAACAACATCA
AACCTAGACTTCTCTCCCCAAACTATCATTCAGAGTCGAGGGCAAAATAAATAGATTTTCTGACTTGGAACAAGTAGGAATAATGTACTT
ATAGTATTCATCTTCATACAGGGATGGACTATAAGTGATTTTTAAAAAACTTCCTACTTGTTCCAAGTCAGAAAAACTATTCATATAGGG
ATGGGCTATTAGCAAGAGTATATGAATAACGTACTATAACAAGAAAAAATGAATTGAGAAGAAAGTAGTGGTTTTAAGAAGGAAAGGAGA
ACAAATAAATTAGTGAAACATAAGGTTAAGTCTATACATATTATTTTCTAATTGCCTATTATGTCAGACTACATGTAGTTAGAAAATACG
ATGAAAGAAAAAGCCATATTATAATTCCAACAAAAAGATAAAATAATTAAGAATAACTGCAACAAGAAAATATAAGTTCTGCAACAATAA
AACTATACAATGAAACTAAAGAGCACAAAAAAGAACTTAAACAGATAAAAAGCAGACCACGTTTTTGGATAAGAAGATTAAAAATTATAA
ATATATCAATTTTCACTGTTAATCTATAAATTCAGTGTAATCCCAATAAAAATGCCAACAGGTTTTCCCCAATAGCATTGAAATGATTTT
AAAATTTAATGAAGGCCAAGCATGGTGGCTCACTCCTGTAATCCCAGCACTTTGAGAGGCCGAGGCAGGTGGATTGCCTGAGTCCAGGAG
TTCCAGACCAGCCTGGACAACATGGTGAAATCCCGTCTCTATTTAAAATGCAAGAAATTAGCTGGGTGTGGTGGTGTGCACCTATAGTCC
TAGCTACTCGGGAGGCTGAGGTGGGAGAATCACCCAAGCCTTGGGAGGTCGAGGCTGTAGTGAGCCAAAATCACATCACTGCACTCCAGT
CTGGGCAGCCAGAGTGAGACCCTGTCTCAAAAAAAAAAAAATTATTGGAAACTACGAGGCAAGAATATCCAAGAAAAATCTAGAAAAGAA
GAAACCTGAGTGAGTCAGCATGACCAAATATTAAAACATCTTATAAAGCTACAATAATTAAAACAATGTGGTGCTGATATGTGGAGGGTC
AATGGAACAAGATGAAATGGCCAAAAATAAATTTAAAATACATGTTGAAATGTATTAACAGCATATGTTAAAGTTAAGTTATGTTAACTT
TATATGTTAAATTCAAGTTAATTGGGGAAAGATGGATTATTCAATATATGATGAACAACTCTGTCACCCAGCTAAAAAAAATTAAGCTTG
GGCCATATGCCAGACTAGATACCAAAATAAATTCCAGGAGGACCAAGTTTTTAAAAGTAAAAATATGGAATCATGGAAGTGCATGAAGAA
GAAGTAGCACTTAAAAAAATAATAATCTCAGCATGGGGAAGGTCTAAGTATGGCCCTCAATCAGAAACCAGGAAGGAAAATATTGACTAT
TTTAAACAAAATTATCTCTGTACCAAAAACAGCATAAAAGGTCAAGAAACAACACACTGGAAAAAGAATTGCAATGAATATCACAGCCAA
ATAGTTAATTTCTTATTTTCAAAAAATAGCTTCTACAAATCGAAGAGAAAAATTCTAAGGTCTCAAAGGAAAAATGAGCAAAGGATTTGA
CAGGTGGTAGAATACAGAAAAAGAATTTAAAATAGCTCCTAAAGATATGGAAACATTACTCATGATAGCAGAAGTATCAATTGACAAAAT
TACTCAGATTGGTAACAAACTTTAAGGGGGAAAGCACTTCCATGCATTGCTGTAAATTGGTACATCTTCTACTGAGAACAATCCGGCAGT
AGTTAACAAAATTGTGAATGCATATATCTCTTTCTCTAGAAATTTCTCTTTTGGGAATTTATTCTACATATATATTCAAACGTGTGAAAT
ACTTCTATACAGGTGATTGAATTTCACTTTATTCCTAAGAGCAGAAGACTGCAAAATAGTAAATATATACCCAAAAGGGTCTAATGGATT
AGTTTTTGGCATATCAGCACATGATAATACTATGAAGCCATAAAAAAGAGAGATCTCTATATGTATTGATGGGGGACCATCTTTAAGATA
TACTGTGGTGTTGAACAAAACAACATGCTGAAAATGTCTCTTATTCTTTTAGAATCAATATAAGTCTGTGCTTGTAAATGCAGTAAGTAT
CTTTGGAAGTATACCTAAAAATTGGTAATAGTGTTTGACTCCAGGGAAGAACAGATGGGTGCCAGAGTGAAAAAAAGATAGCTTTTGCTT
TTTATGACTTTTGGATTCTGTACCACGTAATAATTTTGATGTAAATTTTGCTGTGTGTGTTTTTACTTGTTCATGTAGTGATTTTATAAA
TTACTCTTTTAATTTTCTATCAATGAATATCCTGGGATAAACCCCTCATGATCATAATGAATAATGATGTGTGGAGAGTGGGGAGGGTTT
ACATATGAAAAATGTAGAAAATACAAAAAGTGTCTATATATACAAAAATGTAAGTGTTAACATTTTTATATTTGCTTCAAGCTTTTTTTT

>79093_79093_3_SAMD4B-SLFN5_SAMD4B_chr19_39847729_ENST00000598913_SLFN5_chr17_33591202_ENST00000299977_length(amino acids)=577AA_BP=65
MMFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLESEANSAVFSDRVVYTPESLYKELFSQHKGLR
DLINTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMIVAYSLKQKLVNKGGYTGRLCITPLV
CVLNSDRKAQSVYSSYLQIYPESYNFMTPQHMEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGK
TILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQHIIIDDAQNFRTEDGDWYGKAKFITQTARD
GPGVLWIFLDYFQTYHLSCSGLPPPSDQYPREEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDL
NLEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDLLLQIGDASDVLTDHIVLDSVCRFSGLERN

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Fusion Gene PPI Analysis for SAMD4B-SLFN5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SAMD4B-SLFN5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SAMD4B-SLFN5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource