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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SASH1-MLLT4 (FusionGDB2 ID:79232)

Fusion Gene Summary for SASH1-MLLT4

check button Fusion gene summary
Fusion gene informationFusion gene name: SASH1-MLLT4
Fusion gene ID: 79232
HgeneTgene
Gene symbol

SASH1

MLLT4

Gene ID

23328

4301

Gene nameSAM and SH3 domain containing 1afadin, adherens junction formation factor
SynonymsCAPOK|DUH1|SH3D6A|dJ323M4.1AF6|MLL-AF6|MLLT4|l-afadin
Cytomap

6q24.3-q25.1

6q27

Type of geneprotein-codingprotein-coding
DescriptionSAM and SH3 domain-containing protein 1proline-glutamate repeat-containing proteinafadinALL1-fused gene from chromosome 6 proteinmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4protein AF-6
Modification date2020031320200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000367467, ENST00000367469, 
ENST00000470750, 		ENST00000507679, 
ENST00000344191, ENST00000351017, 
ENST00000366806, ENST00000392108, 
ENST00000392112, ENST00000400822, 
ENST00000447894, 
Fusion gene scores* DoF score9 X 6 X 6=3248 X 5 X 6=240
# samples 88
** MAII scorelog2(8/324*10)=-2.01792190799726
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/240*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SASH1 [Title/Abstract] AND MLLT4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMLLT4(168281197)-SASH1(148711270), # samples:2
SASH1(148841029)-MLLT4(168343809), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSASH1

GO:0000209

protein polyubiquitination

23776175

HgeneSASH1

GO:0010595

positive regulation of endothelial cell migration

23776175

HgeneSASH1

GO:1900044

regulation of protein K63-linked ubiquitination

23776175

HgeneSASH1

GO:1902498

regulation of protein autoubiquitination

23776175


check buttonFusion gene breakpoints across SASH1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MLLT4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-HT-A5RC-01ASASH1chr6

148841029

-MLLT4chr6

168343809

+
ChimerDB4LGGTCGA-HT-A5RCSASH1chr6

148841029

+MLLT4chr6

168343809

+


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Fusion Gene ORF analysis for SASH1-MLLT4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000367467ENST00000507679SASH1chr6

148841029

+MLLT4chr6

168343809

+
In-frameENST00000367467ENST00000344191SASH1chr6

148841029

+MLLT4chr6

168343809

+
In-frameENST00000367467ENST00000351017SASH1chr6

148841029

+MLLT4chr6

168343809

+
In-frameENST00000367467ENST00000366806SASH1chr6

148841029

+MLLT4chr6

168343809

+
In-frameENST00000367467ENST00000392108SASH1chr6

148841029

+MLLT4chr6

168343809

+
In-frameENST00000367467ENST00000392112SASH1chr6

148841029

+MLLT4chr6

168343809

+
In-frameENST00000367467ENST00000400822SASH1chr6

148841029

+MLLT4chr6

168343809

+
In-frameENST00000367467ENST00000447894SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000367469ENST00000344191SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000367469ENST00000351017SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000367469ENST00000366806SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000367469ENST00000392108SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000367469ENST00000392112SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000367469ENST00000400822SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000367469ENST00000447894SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000470750ENST00000344191SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000470750ENST00000351017SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000470750ENST00000366806SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000470750ENST00000392108SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000470750ENST00000392112SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000470750ENST00000400822SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3CDSENST00000470750ENST00000447894SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3UTRENST00000367469ENST00000507679SASH1chr6

148841029

+MLLT4chr6

168343809

+
intron-3UTRENST00000470750ENST00000507679SASH1chr6

148841029

+MLLT4chr6

168343809

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000367467SASH1chr6148841029+ENST00000344191MLLT4chr6168343809+3683168415736031148
ENST00000367467SASH1chr6148841029+ENST00000351017MLLT4chr6168343809+4236168415740801307
ENST00000367467SASH1chr6148841029+ENST00000392108MLLT4chr6168343809+5276168415735611134
ENST00000367467SASH1chr6148841029+ENST00000392112MLLT4chr6168343809+5973168415738851242
ENST00000367467SASH1chr6148841029+ENST00000366806MLLT4chr6168343809+6168168415740801307
ENST00000367467SASH1chr6148841029+ENST00000447894MLLT4chr6168343809+4081168415740801308
ENST00000367467SASH1chr6148841029+ENST00000400822MLLT4chr6168343809+6202168415741131318

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000367467ENST00000344191SASH1chr6148841029+MLLT4chr6168343809+0.00461470.99538535
ENST00000367467ENST00000351017SASH1chr6148841029+MLLT4chr6168343809+0.005395250.99460477
ENST00000367467ENST00000392108SASH1chr6148841029+MLLT4chr6168343809+0.0011221040.99887794
ENST00000367467ENST00000392112SASH1chr6148841029+MLLT4chr6168343809+0.0005006050.99949944
ENST00000367467ENST00000366806SASH1chr6148841029+MLLT4chr6168343809+0.0009293310.9990707
ENST00000367467ENST00000447894SASH1chr6148841029+MLLT4chr6168343809+0.0067764650.99322355
ENST00000367467ENST00000400822SASH1chr6148841029+MLLT4chr6168343809+0.0006314160.9993686

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Fusion Genomic Features for SASH1-MLLT4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SASH1chr6148841029+MLLT4chr6168343808+1.07E-050.9999894
SASH1chr6148841029+MLLT4chr6168343808+1.07E-050.9999894

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SASH1-MLLT4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:168281197/chr6:148711270)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSASH1chr6:148841029chr6:168343809ENST00000367467+10209_334031248.0Compositional biasNote=Pro-rich
TgeneMLLT4chr6:148841029chr6:168343809ENST0000039210821301408_144810261652.0Coiled coilOntology_term=ECO:0000255
TgeneMLLT4chr6:148841029chr6:168343809ENST0000039210821301523_166710261652.0Coiled coilOntology_term=ECO:0000255
TgeneMLLT4chr6:148841029chr6:168343809ENST0000040082221341408_144810251835.0Coiled coilOntology_term=ECO:0000255
TgeneMLLT4chr6:148841029chr6:168343809ENST0000040082221341523_166710251835.0Coiled coilOntology_term=ECO:0000255
TgeneMLLT4chr6:148841029chr6:168343809ENST0000044789421331408_144810261825.0Coiled coilOntology_term=ECO:0000255
TgeneMLLT4chr6:148841029chr6:168343809ENST0000044789421331523_166710261825.0Coiled coilOntology_term=ECO:0000255
TgeneMLLT4chr6:148841029chr6:168343809ENST0000039210821301346_139210261652.0Compositional biasNote=Pro-rich
TgeneMLLT4chr6:148841029chr6:168343809ENST0000039210821301578_158810261652.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMLLT4chr6:148841029chr6:168343809ENST0000039210821301678_170810261652.0Compositional biasNote=Pro-rich
TgeneMLLT4chr6:148841029chr6:168343809ENST0000040082221341346_139210251835.0Compositional biasNote=Pro-rich
TgeneMLLT4chr6:148841029chr6:168343809ENST0000040082221341578_158810251835.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMLLT4chr6:148841029chr6:168343809ENST0000040082221341678_170810251835.0Compositional biasNote=Pro-rich
TgeneMLLT4chr6:148841029chr6:168343809ENST0000044789421331346_139210261825.0Compositional biasNote=Pro-rich
TgeneMLLT4chr6:148841029chr6:168343809ENST0000044789421331578_158810261825.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMLLT4chr6:148841029chr6:168343809ENST0000044789421331678_170810261825.0Compositional biasNote=Pro-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSASH1chr6:148841029chr6:168343809ENST00000367467+1020978_10594031248.0Compositional biasNote=Pro-rich
HgeneSASH1chr6:148841029chr6:168343809ENST00000367467+10201177_12414031248.0DomainSAM 2
HgeneSASH1chr6:148841029chr6:168343809ENST00000367467+1020554_6154031248.0DomainSH3
HgeneSASH1chr6:148841029chr6:168343809ENST00000367467+1020633_6974031248.0DomainSAM 1
TgeneMLLT4chr6:148841029chr6:168343809ENST000003921082130146_18510261652.0Coiled coilOntology_term=ECO:0000255
TgeneMLLT4chr6:148841029chr6:168343809ENST000004008222134146_18510251835.0Coiled coilOntology_term=ECO:0000255
TgeneMLLT4chr6:148841029chr6:168343809ENST000004478942133146_18510261825.0Coiled coilOntology_term=ECO:0000255
TgeneMLLT4chr6:148841029chr6:168343809ENST000003921082130163_17510261652.0Compositional biasNote=Glu/Lys-rich
TgeneMLLT4chr6:148841029chr6:168343809ENST000004008222134163_17510251835.0Compositional biasNote=Glu/Lys-rich
TgeneMLLT4chr6:148841029chr6:168343809ENST000004478942133163_17510261825.0Compositional biasNote=Glu/Lys-rich
TgeneMLLT4chr6:148841029chr6:168343809ENST0000039210821301007_109310261652.0DomainPDZ
TgeneMLLT4chr6:148841029chr6:168343809ENST000003921082130246_34810261652.0DomainRas-associating 2
TgeneMLLT4chr6:148841029chr6:168343809ENST00000392108213039_13310261652.0DomainRas-associating 1
TgeneMLLT4chr6:148841029chr6:168343809ENST000003921082130426_49210261652.0DomainNote=FHA
TgeneMLLT4chr6:148841029chr6:168343809ENST000003921082130668_90810261652.0DomainDilute
TgeneMLLT4chr6:148841029chr6:168343809ENST0000040082221341007_109310251835.0DomainPDZ
TgeneMLLT4chr6:148841029chr6:168343809ENST000004008222134246_34810251835.0DomainRas-associating 2
TgeneMLLT4chr6:148841029chr6:168343809ENST00000400822213439_13310251835.0DomainRas-associating 1
TgeneMLLT4chr6:148841029chr6:168343809ENST000004008222134426_49210251835.0DomainNote=FHA
TgeneMLLT4chr6:148841029chr6:168343809ENST000004008222134668_90810251835.0DomainDilute
TgeneMLLT4chr6:148841029chr6:168343809ENST0000044789421331007_109310261825.0DomainPDZ
TgeneMLLT4chr6:148841029chr6:168343809ENST000004478942133246_34810261825.0DomainRas-associating 2
TgeneMLLT4chr6:148841029chr6:168343809ENST00000447894213339_13310261825.0DomainRas-associating 1
TgeneMLLT4chr6:148841029chr6:168343809ENST000004478942133426_49210261825.0DomainNote=FHA
TgeneMLLT4chr6:148841029chr6:168343809ENST000004478942133668_90810261825.0DomainDilute


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Fusion Gene Sequence for SASH1-MLLT4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>79232_79232_1_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000344191_length(transcript)=3683nt_BP=1684nt
ATTTTGAAGAGAGGGGTCCCGGGGAGCTCCCTCCAAGATCTAGAGGCTCCGCGGCCACCCCTGCCGGGTCCTGCCAAGACTTGCTAGAAG
GAACGAGTCGCGTGCCTTAGTTAGTTGGTTCCCGTCACAGGAAGAAACGCCTTTGCAGTGGGTTTAATTGCTTCTGGGCCGAGCGAATTC
CCCGCCGTACAACTCAGTGGTGCGGACTTTGCCTCCTGCTACCCTGTTGCTGCGCCGAGCGGGGTGGGAAAGTTTCTGGAGTTGTCAGTC
GCGCAGCCCGTGGCCACCTAGACCCGAGGTGCGGGCGCCTGCGAAGGGCCCCCGCGGGGTGGCCGGGGCCGCCGGGGCATGCAGCGCGGG
GGCGCGGCTCGGTGACGCCGCGGGCGGGGACCCGGCATCCGGGCAGGCTGCGCGCGGGTGCGGGGCGAGGGCGCCGCGGGGACTGGGACG
CACGGCCCGCGCGCGGGACACGGCCATGGAGGACGCGGGAGCAGCTGGCCCGGGGCCGGAGCCTGAGCCCGAGCCCGAGCCGGAGCCCGA
GCCCGCGCCGGAGCCGGAACCGGAGCCCAAGCCGGGTGCTGGCACATCCGAGGCGTTCTCCCGACTCTGGACCGACGTGATGGGTATCCT
GGACGGTTCACTGGGAAACATCGATGACCTGGCGCAGCAGTATGCAGATTATTACAACACCTGTTTCTCCGACGTGTGCGAGAGGATGGA
GGAGCTGCGGAAACGGCGGGTTTCCCAGGACCTGGAAGTGGAGAAACCCGATGCTAGCCCCACGTCACTTCAGCTGCGGTCCCAGATCGA
AGAGTCGCTTGGCTTCTGTAGCGCCGTGTCAACCCCAGAAGTGGAAAGAAAGAACCCTCTTCATAAATCAAACTCAGAAGACAGCTCTGT
AGGAAAAGGAGACTGGAAGAAGAAAAATAAGTATTTCTGGCAGAACTTCCGAAAGAACCAGAAAGGAATAATGAGACAGACTTCAAAAGG
AGAAGACGTTGGTTATGTTGCCAGTGAAATAACGATGAGCGATGAGGAGCGGATTCAGCTAATGATGATGGTCAAAGAAAAGATGATCAC
AATTGAGGAAGCACTTGCTAGGCTCAAGGAATACGAGGCCCAGCACCGGCAGTCGGCTGCCCTGGACCCTGCTGACTGGCCAGATGGTTC
TTACCCAACGTTTGATGGCTCATCAAACTGCAATTCAAGAGAACAATCGGATGATGAGACTGAGGAGTCGGTGAAGTTTAAGAGGTTACA
CAAGCTGGTAAACTCCACTCGCAGAGTCAGAAAGAAACTAATTAGGGTGGAAGAAATGAAAAAACCCAGCACTGAAGGTGGGGAGGAGCA
CGTGTTTGAGAATTCGCCGGTCCTGGATGAACGGTCCGCCCTCTACTCTGGCGTGCACAAGAAGCCCCTTTTCTTTGATGGCTCTCCTGA
GAAACCTCCCGAAGATGACTCAGACTCTCTCACCACGTCTCCATCCTCCAGCAGCCTGGACACCTGGGGGGCTGGCCGGAAGTTGGTCAA
AACCTTCAGCAAAGGAGAGAGCCGGGGCCTGATTAAGCCCCCCAAGAAGATGGGGACATTCTTCTCCTACCCAGAAGAAGAAAAGGCCCA
GAAAGTGTCCCGCTCCCTCACCGAGGGGGAGATGAAGAAGGGTCTCGGGTCCCTAAGCCACGGGGGTGCTGGTCAAGATAAACTAGGAAT
CTATGTGAAGTCGGTTGTGAAAGGAGGTGCTGCAGATGTGGATGGACGTCTAGCTGCAGGTGATCAGCTCCTCAGTGTGGATGGACGAAG
TCTGGTTGGACTCTCTCAGGAAAGGGCGGCAGAACTCATGACAAGAACAAGCTCTGTGGTGACACTGGAAGTAGCAAAGCAGGGTGCCAT
CTACCACGGTCTGGCCACCCTTCTCAATCAGCCATCCCCCATGATGCAGAGAATTTCAGATCGTCGTGGCTCAGGTAAACCCCGACCAAA
GAGTGAAGGCTTTGAGCTCTATAATAATTCAACTCAAAATGGGTCTCCTGAGAGTCCTCAGCTGCCTTGGGCAGAATATAGTGAACCAAA
GAAATTGCCTGGTGATGACAGACTGATGAAAAATAGAGCTGATCACCGTTCCAGCCCCAACGTAGCAAATCAGCCTCCTAGTCCTGGAGG
GAAAAGTGCATATGCCTCTGGAACAACAGCGAAGATAACATCTGTCTCTACTGGAAACCTCTGCACTGAGGAGCAGACGCCTCCGCCTAG
ACCTGAAGCCTACCCCATCCCCACTCAGACGTACACCAGAGAGTATTTTACCTTCCCAGCTTCCAAATCCCAGGATCGGATGGCTCCTCC
TCAGAACCAGTGGCCAAATTATGAGGAAAAGCCACATATGCACACAGATAGTAATCATTCCAGTATTGCAATTCAGCGTGTTACACGTTC
CCAAGAAGAACTTCGAGAAGATAAAGCTTACCAACTTGAGCGGCATCGAATAGAGGCAGCTATGGACCGAAAGTCTGATAGTGATATGTG
GATAAATCAGAGCTCCTCACTGGACTCCAGTACCTCTAGCCAGGAGCATCTGAACCATTCCTCTAAGTCGGTCACCCCTGCTTCCACACT
GACCAAAAGTGGCCCTGGCCGTTGGAAAACACCAGCAGCCATACCGGCCACCCCTGTGGCCGTCTCCCAGCCAATCCGAACAGACCTGCC
TCCGCCACCCCCGCCACCTCCAGTCCACTATGCCGGTGATTTCGATGGAATGTCCATGGATTTGCCTCTCCCACCACCCCCTTCCGCCAA
CCAGATAGGGCTGCCGTCTGCGCAGGTGGCTGCTGCTGAACGGAGAAAGAGAGAAGAACATCAGCGTTGGTATGAGAAGGAGAAGGCCCG
CCTGGAGGAGGAGCGGGAGAGGAAGCGGAGAGAGCAGGAGAGGAAGTTGGGCCAGATGCGCACTCAGTCCTTAAACCCTGCTCCGTTTTC
TCCCCTGACTGCACAGCAGATGAAGCCCGAAAAGCCTTCCACACTCCAGCGGCCACAGGAAACAGTCATTCGGGAGCTGCAGCCTCAGCA
GCAGCCCCGCACGATCGAGCGCAGAGACTTGCAGTACATTACAGTCAGCAAAGAGGAGCTTTCCTCGGGGGACAGTCTGTCCCCCGACCC
GTGGAAGCGGGACGCCAAGGAGAAGCTGGAGAAGCAGCAGCAGATGCACATCGTGGACATGCTGAGCAAGGAGATCCAGGAGCTCCAGAG
CAAACCGGACCGCAGCGCCGAGGAGAGCGACCGGCTGCGCAAGCTCATGCTGGAGTGGCAGTTCCAGAAGAGACTCCAGGAGTCGAAGCA
GAAGGACGAAGATGACGAGGAGGAGGAGGACGATGATGTGGACACCATGCTGATCATGCAGCGCCTGGAGGCTGAACGAAGAGCGAGGCA
GACTGCTATGCCAGCAATCTCTGTTCTAGATTTGTTGCAGGACGAGGAGCGGAGGCGGCAGCAGCAGTTAGAAGAGATGCGCAAGCGGGA
AGCGGAAGACCGAGCGAGGCAAGAGGAAGAGCGCCGGCGGCAGGAGGAGGAGCGAACAAAACGAGACGCTGAAGAAAAGGTTATGGTCCT

>79232_79232_1_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000344191_length(amino acids)=1148AA_BP=509
MLLGRANSPPYNSVVRTLPPATLLLRRAGWESFWSCQSRSPWPPRPEVRAPAKGPRGVAGAAGACSAGARLGDAAGGDPASGQAARGCGA
RAPRGLGRTARARDTAMEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNIDDLAQQYADYYNTCF
SDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSAVSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKG
IMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSSNCNSREQSDDETEE
SVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVLDERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTW
GAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQ
LLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLP
WAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASK
SQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSK
SVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQR
WYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSS
GDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRL

--------------------------------------------------------------
>79232_79232_2_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000351017_length(transcript)=4236nt_BP=1684nt
ATTTTGAAGAGAGGGGTCCCGGGGAGCTCCCTCCAAGATCTAGAGGCTCCGCGGCCACCCCTGCCGGGTCCTGCCAAGACTTGCTAGAAG
GAACGAGTCGCGTGCCTTAGTTAGTTGGTTCCCGTCACAGGAAGAAACGCCTTTGCAGTGGGTTTAATTGCTTCTGGGCCGAGCGAATTC
CCCGCCGTACAACTCAGTGGTGCGGACTTTGCCTCCTGCTACCCTGTTGCTGCGCCGAGCGGGGTGGGAAAGTTTCTGGAGTTGTCAGTC
GCGCAGCCCGTGGCCACCTAGACCCGAGGTGCGGGCGCCTGCGAAGGGCCCCCGCGGGGTGGCCGGGGCCGCCGGGGCATGCAGCGCGGG
GGCGCGGCTCGGTGACGCCGCGGGCGGGGACCCGGCATCCGGGCAGGCTGCGCGCGGGTGCGGGGCGAGGGCGCCGCGGGGACTGGGACG
CACGGCCCGCGCGCGGGACACGGCCATGGAGGACGCGGGAGCAGCTGGCCCGGGGCCGGAGCCTGAGCCCGAGCCCGAGCCGGAGCCCGA
GCCCGCGCCGGAGCCGGAACCGGAGCCCAAGCCGGGTGCTGGCACATCCGAGGCGTTCTCCCGACTCTGGACCGACGTGATGGGTATCCT
GGACGGTTCACTGGGAAACATCGATGACCTGGCGCAGCAGTATGCAGATTATTACAACACCTGTTTCTCCGACGTGTGCGAGAGGATGGA
GGAGCTGCGGAAACGGCGGGTTTCCCAGGACCTGGAAGTGGAGAAACCCGATGCTAGCCCCACGTCACTTCAGCTGCGGTCCCAGATCGA
AGAGTCGCTTGGCTTCTGTAGCGCCGTGTCAACCCCAGAAGTGGAAAGAAAGAACCCTCTTCATAAATCAAACTCAGAAGACAGCTCTGT
AGGAAAAGGAGACTGGAAGAAGAAAAATAAGTATTTCTGGCAGAACTTCCGAAAGAACCAGAAAGGAATAATGAGACAGACTTCAAAAGG
AGAAGACGTTGGTTATGTTGCCAGTGAAATAACGATGAGCGATGAGGAGCGGATTCAGCTAATGATGATGGTCAAAGAAAAGATGATCAC
AATTGAGGAAGCACTTGCTAGGCTCAAGGAATACGAGGCCCAGCACCGGCAGTCGGCTGCCCTGGACCCTGCTGACTGGCCAGATGGTTC
TTACCCAACGTTTGATGGCTCATCAAACTGCAATTCAAGAGAACAATCGGATGATGAGACTGAGGAGTCGGTGAAGTTTAAGAGGTTACA
CAAGCTGGTAAACTCCACTCGCAGAGTCAGAAAGAAACTAATTAGGGTGGAAGAAATGAAAAAACCCAGCACTGAAGGTGGGGAGGAGCA
CGTGTTTGAGAATTCGCCGGTCCTGGATGAACGGTCCGCCCTCTACTCTGGCGTGCACAAGAAGCCCCTTTTCTTTGATGGCTCTCCTGA
GAAACCTCCCGAAGATGACTCAGACTCTCTCACCACGTCTCCATCCTCCAGCAGCCTGGACACCTGGGGGGCTGGCCGGAAGTTGGTCAA
AACCTTCAGCAAAGGAGAGAGCCGGGGCCTGATTAAGCCCCCCAAGAAGATGGGGACATTCTTCTCCTACCCAGAAGAAGAAAAGGCCCA
GAAAGTGTCCCGCTCCCTCACCGAGGGGGAGATGAAGAAGGGTCTCGGGTCCCTAAGCCACGGGGGTGCTGGTCAAGATAAACTAGGAAT
CTATGTGAAGTCGGTTGTGAAAGGAGGTGCTGCAGATGTGGATGGACGTCTAGCTGCAGGTGATCAGCTCCTCAGTGTGGATGGACGAAG
TCTGGTTGGACTCTCTCAGGAAAGGGCGGCAGAACTCATGACAAGAACAAGCTCTGTGGTGACACTGGAAGTAGCAAAGCAGGGTGCCAT
CTACCACGGTCTGGCCACCCTTCTCAATCAGCCATCCCCCATGATGCAGAGAATTTCAGATCGTCGTGGCTCAGGTAAACCCCGACCAAA
GAGTGAAGGCTTTGAGCTCTATAATAATTCAACTCAAAATGGGTCTCCTGAGAGTCCTCAGCTGCCTTGGGCAGAATATAGTGAACCAAA
GAAATTGCCTGGTGATGACAGACTGATGAAAAATAGAGCTGATCACCGTTCCAGCCCCAACGTAGCAAATCAGCCTCCTAGTCCTGGAGG
GAAAAGTGCATATGCCTCTGGAACAACAGCGAAGATAACATCTGTCTCTACTGGAAACCTCTGCACTGAGGAGCAGACGCCTCCGCCTAG
ACCTGAAGCCTACCCCATCCCCACTCAGACGTACACCAGAGAGTATTTTACCTTCCCAGCTTCCAAATCCCAGGATCGGATGGCTCCTCC
TCAGAACCAGTGGCCAAATTATGAGGAAAAGCCACATATGCACACAGATAGTAATCATTCCAGTATTGCAATTCAGCGTGTTACACGTTC
CCAAGAAGAACTTCGAGAAGATAAAGCTTACCAACTTGAGCGGCATCGAATAGAGGCAGCTATGGACCGAAAGTCTGATAGTGATATGTG
GATAAATCAGAGCTCCTCACTGGACTCCAGTACCTCTAGCCAGGAGCATCTGAACCATTCCTCTAAGTCGGTCACCCCTGCTTCCACACT
GACCAAAAGTGGCCCTGGCCGTTGGAAAACACCAGCAGCCATACCGGCCACCCCTGTGGCCGTCTCCCAGCCAATCCGAACAGACCTGCC
TCCGCCACCCCCGCCACCTCCAGTCCACTATGCCGGTGATTTCGATGGAATGTCCATGGATTTGCCTCTCCCACCACCCCCTTCCGCCAA
CCAGATAGGGCTGCCGTCTGCGCAGGTGGCTGCTGCTGAACGGAGAAAGAGAGAAGAACATCAGCGTTGGTATGAGAAGGAGAAGGCCCG
CCTGGAGGAGGAGCGGGAGAGGAAGCGGAGAGAGCAGGAGAGGAAGTTGGGCCAGATGCGCACTCAGTCCTTAAACCCTGCTCCGTTTTC
TCCCCTGACTGCACAGCAGATGAAGCCCGAAAAGCCTTCCACACTCCAGCGGCCACAGGAAACAGTCATTCGGGAGCTGCAGCCTCAGCA
GCAGCCCCGCACGATCGAGCGCAGAGACTTGCAGTACATTACAGTCAGCAAAGAGGAGCTTTCCTCGGGGGACAGTCTGTCCCCCGACCC
GTGGAAGCGGGACGCCAAGGAGAAGCTGGAGAAGCAGCAGCAGATGCACATCGTGGACATGCTGAGCAAGGAGATCCAGGAGCTCCAGAG
CAAACCGGACCGCAGCGCCGAGGAGAGCGACCGGCTGCGCAAGCTCATGCTGGAGTGGCAGTTCCAGAAGAGACTCCAGGAGTCGAAGCA
GAAGGACGAAGATGACGAGGAGGAGGAGGACGATGATGTGGACACCATGCTGATCATGCAGCGCCTGGAGGCTGAACGAAGAGCGAGGTT
GCAGGACGAGGAGCGGAGGCGGCAGCAGCAGTTAGAAGAGATGCGCAAGCGGGAAGCGGAAGACCGAGCGAGGCAAGAGGAAGAGCGCCG
GCGGCAGGAGGAGGAGCGAACAAAACGAGACGCTGAAGAAAAGAGGCGACAGGAAGAAGGGTATTACAGCCGCCTGGAAGCCGAGAGGCG
CAGACAGCACGACGAGGCGGCGCGCAGGTTGCTGGAGCCCGAGGCGCCCGGTCTGTGCCGCCCTCCGCTTCCCCGGGACTACGAGCCCCC
GTCCCCGTCCCCCGCGCCCGGCGCCCCTCCTCCCCCGCCTCAGCGAAACGCCTCCTACCTCAAAACACAGGTCCTCTCCCCCGACTCGCT
GTTCACTGCCAAGTTTGTTGCATACAATGAGGAGGAGGAGGAGGAGGACTGCAGCCTAGCAGGACCAAACTCTTACCCAGGATCTACTGG
AGCAGCTGTTGGAGCCCATGACGCCTGTCGGGATGCAAAAGAGAAGCGCTCTAAAAGCCAAGATGCAGATTCACCTGGAAGTTCTGGGGC
CCCTGAAAACTTGACATTCAAGGAACGCCAGCGTCTTTTTTCACAAGGTCAAGATGTATCCAATAAAGTGAAAGCTTCTCGTAAATTAAC
AGAACTGGAGAATGAACTGAACACAAAGTGAAAGAAAATGAGGAGAACACTTTGTATTTACCCCAAAATCTTTTCAGTTGTGGGTTTGTA
GGTGCGAGTTTGAAGAGGAAAAGAGGAAGGGGGTTATATTTCTAAGTGATTTACAATTTCTGTTTCTAAAATTGTTGGGATTTAGAAATG

>79232_79232_2_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000351017_length(amino acids)=1307AA_BP=509
MLLGRANSPPYNSVVRTLPPATLLLRRAGWESFWSCQSRSPWPPRPEVRAPAKGPRGVAGAAGACSAGARLGDAAGGDPASGQAARGCGA
RAPRGLGRTARARDTAMEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNIDDLAQQYADYYNTCF
SDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSAVSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKG
IMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSSNCNSREQSDDETEE
SVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVLDERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTW
GAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQ
LLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLP
WAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASK
SQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSK
SVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQR
WYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSS
GDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRL
EAERRARLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGLCRPP
LPRDYEPPSPSPAPGAPPPPPQRNASYLKTQVLSPDSLFTAKFVAYNEEEEEEDCSLAGPNSYPGSTGAAVGAHDACRDAKEKRSKSQDA

--------------------------------------------------------------
>79232_79232_3_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000366806_length(transcript)=6168nt_BP=1684nt
ATTTTGAAGAGAGGGGTCCCGGGGAGCTCCCTCCAAGATCTAGAGGCTCCGCGGCCACCCCTGCCGGGTCCTGCCAAGACTTGCTAGAAG
GAACGAGTCGCGTGCCTTAGTTAGTTGGTTCCCGTCACAGGAAGAAACGCCTTTGCAGTGGGTTTAATTGCTTCTGGGCCGAGCGAATTC
CCCGCCGTACAACTCAGTGGTGCGGACTTTGCCTCCTGCTACCCTGTTGCTGCGCCGAGCGGGGTGGGAAAGTTTCTGGAGTTGTCAGTC
GCGCAGCCCGTGGCCACCTAGACCCGAGGTGCGGGCGCCTGCGAAGGGCCCCCGCGGGGTGGCCGGGGCCGCCGGGGCATGCAGCGCGGG
GGCGCGGCTCGGTGACGCCGCGGGCGGGGACCCGGCATCCGGGCAGGCTGCGCGCGGGTGCGGGGCGAGGGCGCCGCGGGGACTGGGACG
CACGGCCCGCGCGCGGGACACGGCCATGGAGGACGCGGGAGCAGCTGGCCCGGGGCCGGAGCCTGAGCCCGAGCCCGAGCCGGAGCCCGA
GCCCGCGCCGGAGCCGGAACCGGAGCCCAAGCCGGGTGCTGGCACATCCGAGGCGTTCTCCCGACTCTGGACCGACGTGATGGGTATCCT
GGACGGTTCACTGGGAAACATCGATGACCTGGCGCAGCAGTATGCAGATTATTACAACACCTGTTTCTCCGACGTGTGCGAGAGGATGGA
GGAGCTGCGGAAACGGCGGGTTTCCCAGGACCTGGAAGTGGAGAAACCCGATGCTAGCCCCACGTCACTTCAGCTGCGGTCCCAGATCGA
AGAGTCGCTTGGCTTCTGTAGCGCCGTGTCAACCCCAGAAGTGGAAAGAAAGAACCCTCTTCATAAATCAAACTCAGAAGACAGCTCTGT
AGGAAAAGGAGACTGGAAGAAGAAAAATAAGTATTTCTGGCAGAACTTCCGAAAGAACCAGAAAGGAATAATGAGACAGACTTCAAAAGG
AGAAGACGTTGGTTATGTTGCCAGTGAAATAACGATGAGCGATGAGGAGCGGATTCAGCTAATGATGATGGTCAAAGAAAAGATGATCAC
AATTGAGGAAGCACTTGCTAGGCTCAAGGAATACGAGGCCCAGCACCGGCAGTCGGCTGCCCTGGACCCTGCTGACTGGCCAGATGGTTC
TTACCCAACGTTTGATGGCTCATCAAACTGCAATTCAAGAGAACAATCGGATGATGAGACTGAGGAGTCGGTGAAGTTTAAGAGGTTACA
CAAGCTGGTAAACTCCACTCGCAGAGTCAGAAAGAAACTAATTAGGGTGGAAGAAATGAAAAAACCCAGCACTGAAGGTGGGGAGGAGCA
CGTGTTTGAGAATTCGCCGGTCCTGGATGAACGGTCCGCCCTCTACTCTGGCGTGCACAAGAAGCCCCTTTTCTTTGATGGCTCTCCTGA
GAAACCTCCCGAAGATGACTCAGACTCTCTCACCACGTCTCCATCCTCCAGCAGCCTGGACACCTGGGGGGCTGGCCGGAAGTTGGTCAA
AACCTTCAGCAAAGGAGAGAGCCGGGGCCTGATTAAGCCCCCCAAGAAGATGGGGACATTCTTCTCCTACCCAGAAGAAGAAAAGGCCCA
GAAAGTGTCCCGCTCCCTCACCGAGGGGGAGATGAAGAAGGGTCTCGGGTCCCTAAGCCACGGGGGTGCTGGTCAAGATAAACTAGGAAT
CTATGTGAAGTCGGTTGTGAAAGGAGGTGCTGCAGATGTGGATGGACGTCTAGCTGCAGGTGATCAGCTCCTCAGTGTGGATGGACGAAG
TCTGGTTGGACTCTCTCAGGAAAGGGCGGCAGAACTCATGACAAGAACAAGCTCTGTGGTGACACTGGAAGTAGCAAAGCAGGGTGCCAT
CTACCACGGTCTGGCCACCCTTCTCAATCAGCCATCCCCCATGATGCAGAGAATTTCAGATCGTCGTGGCTCAGGTAAACCCCGACCAAA
GAGTGAAGGCTTTGAGCTCTATAATAATTCAACTCAAAATGGGTCTCCTGAGAGTCCTCAGCTGCCTTGGGCAGAATATAGTGAACCAAA
GAAATTGCCTGGTGATGACAGACTGATGAAAAATAGAGCTGATCACCGTTCCAGCCCCAACGTAGCAAATCAGCCTCCTAGTCCTGGAGG
GAAAAGTGCATATGCCTCTGGAACAACAGCGAAGATAACATCTGTCTCTACTGGAAACCTCTGCACTGAGGAGCAGACGCCTCCGCCTAG
ACCTGAAGCCTACCCCATCCCCACTCAGACGTACACCAGAGAGTATTTTACCTTCCCAGCTTCCAAATCCCAGGATCGGATGGCTCCTCC
TCAGAACCAGTGGCCAAATTATGAGGAAAAGCCACATATGCACACAGATAGTAATCATTCCAGTATTGCAATTCAGCGTGTTACACGTTC
CCAAGAAGAACTTCGAGAAGATAAAGCTTACCAACTTGAGCGGCATCGAATAGAGGCAGCTATGGACCGAAAGTCTGATAGTGATATGTG
GATAAATCAGAGCTCCTCACTGGACTCCAGTACCTCTAGCCAGGAGCATCTGAACCATTCCTCTAAGTCGGTCACCCCTGCTTCCACACT
GACCAAAAGTGGCCCTGGCCGTTGGAAAACACCAGCAGCCATACCGGCCACCCCTGTGGCCGTCTCCCAGCCAATCCGAACAGACCTGCC
TCCGCCACCCCCGCCACCTCCAGTCCACTATGCCGGTGATTTCGATGGAATGTCCATGGATTTGCCTCTCCCACCACCCCCTTCCGCCAA
CCAGATAGGGCTGCCGTCTGCGCAGGTGGCTGCTGCTGAACGGAGAAAGAGAGAAGAACATCAGCGTTGGTATGAGAAGGAGAAGGCCCG
CCTGGAGGAGGAGCGGGAGAGGAAGCGGAGAGAGCAGGAGAGGAAGTTGGGCCAGATGCGCACTCAGTCCTTAAACCCTGCTCCGTTTTC
TCCCCTGACTGCACAGCAGATGAAGCCCGAAAAGCCTTCCACACTCCAGCGGCCACAGGAAACAGTCATTCGGGAGCTGCAGCCTCAGCA
GCAGCCCCGCACGATCGAGCGCAGAGACTTGCAGTACATTACAGTCAGCAAAGAGGAGCTTTCCTCGGGGGACAGTCTGTCCCCCGACCC
GTGGAAGCGGGACGCCAAGGAGAAGCTGGAGAAGCAGCAGCAGATGCACATCGTGGACATGCTGAGCAAGGAGATCCAGGAGCTCCAGAG
CAAACCGGACCGCAGCGCCGAGGAGAGCGACCGGCTGCGCAAGCTCATGCTGGAGTGGCAGTTCCAGAAGAGACTCCAGGAGTCGAAGCA
GAAGGACGAAGATGACGAGGAGGAGGAGGACGATGATGTGGACACCATGCTGATCATGCAGCGCCTGGAGGCTGAACGAAGAGCGAGGTT
GCAGGACGAGGAGCGGAGGCGGCAGCAGCAGTTAGAAGAGATGCGCAAGCGGGAAGCGGAAGACCGAGCGAGGCAAGAGGAAGAGCGCCG
GCGGCAGGAGGAGGAGCGAACAAAACGAGACGCTGAAGAAAAGAGGCGACAGGAAGAAGGGTATTACAGCCGCCTGGAAGCCGAGAGGCG
CAGACAGCACGACGAGGCGGCGCGCAGGTTGCTGGAGCCCGAGGCGCCCGGTCTGTGCCGCCCTCCGCTTCCCCGGGACTACGAGCCCCC
GTCCCCGTCCCCCGCGCCCGGCGCCCCTCCTCCCCCGCCTCAGCGAAACGCCTCCTACCTCAAAACACAGGTCCTCTCCCCCGACTCGCT
GTTCACTGCCAAGTTTGTTGCATACAATGAGGAGGAGGAGGAGGAGGACTGCAGCCTAGCAGGACCAAACTCTTACCCAGGATCTACTGG
AGCAGCTGTTGGAGCCCATGACGCCTGTCGGGATGCAAAAGAGAAGCGCTCTAAAAGCCAAGATGCAGATTCACCTGGAAGTTCTGGGGC
CCCTGAAAACTTGACATTCAAGGAACGCCAGCGTCTTTTTTCACAAGGTCAAGATGTATCCAATAAAGTGAAAGCTTCTCGTAAATTAAC
AGAACTGGAGAATGAACTGAACACAAAGTGAAAGAAAATGAGGAGAACACTTTGTATTTACCCCAAAATCTTTTCAGTTGTGGGTTTGTA
GGTGCGAGTTTGAAGAGGAAAAGAGGAAGGGGGTTATATTTCTAAGTGATTTACAATTTCTGTTTCTAAAATTGTTGGGATTTAGAAATG
TTTCAATTCCAAGAAATTTTATTTTACTTTACCATGAGATTGCCATTTATGTAATTTAAACACTGTCTAGTTTCTTAATTATCTAACTCA
CACGAGGGTAAGTTTTTTGTTGGTTTCTTTTTTGGAGTCCTGAGTTCAAAGGGGACAGAACTAAGGGCAGGAGAAGAGAATGGATGTGTC
TTCTCTCCCATCTTCCCCTCATCATCGACCGAGGAGCACAAAGAAGTTCTGTTTCTGTTTTTTTCAGAAACTTTATTTTAGCTGTCAAGC
AGAGAATAGCTTGAACTATTCAGACTATTGTTGGCACTGTTTAGTAGTGACCACACGCTCTTCTACCCGGGAAGGAACATATGACGACAT
GCTCCTCCCATGTCCCCTGATGGTGTCTGTTCCCACAATATCCTTCTAGTCTGCATCGTGAAGTGGCTTAGGCCAAAGCTTCCTGTGTGA
TGACGCACGTCCGAGACTGTTCCATCTCATTCCTCGCAAATTTGAGCTCTTCTGATCAATTCTAAATATTTGATTAATTTTAATTCTGAA
AGAAAATTTTGAGGATTTAAGCTTAGGGGATTTTATTTTTATAAATACCAGATTATTGTTAGACTTAATAAATCACTGTTAAATTTAAAG
ATGACAGTTACCTTGGAAAGTTCACTAATACTTCGCTCCAAGGCGTCTGTAAAAGAAGATATCTTTATTGGAGCAATGTTCATGTGACTG
GGAATGACAGAAGAATGGGAGATGAGTAGGGACCCCTCAAGCACAGCTGTCACTCAGAAATTTTAAATTTGAAAAAGAAATCGATTTTCA
TCTGTATGCCGTCAAGGAAGGAATTCAGTTACAGGGCATCTGTAACTTAAATATTGTAAGAATAACTCATATGGAAGTTCAAGCTATTTT
TATACTATAATAGAGTTATTTAATTTTAATTTGTTGAATTATTAGTTACCACTGTCATTTCTTCAGCTATGGATATGTGGCTGATGTTGG
GGAGACGGACCTCAGTGTGTTTTATATTGTCTGGTGTTAAGATGATAAATTACTTTGTGATTACAAGCAAATTTTCTATTTGACAAAGCC
CTTGGTGGAGTCCAAATGATTTTTCTGTACCATATTGTTCTCTTACACATACGTATGTTAGGAAAATAGGCACACTTTCAAAGAGAATGT
TCTCTTACACATACGTATGTTAGGAAAATAGACACATTTTCAAAGAGAATGTTCTCTTACATATGTTAGGAAAATAGGCACACTTTCAAA
GAGAGGTATAGGGGCTTTTTACTGCCTTCGAAATCACTTTTAATAAAAGTTGTATGATAAATCATTAAAAATGCGAGTGTAAATATTTTT
TTTTACCTCTATCAGGGTTTTTATTTGAAAGTGTGCTCTTACCATTTCCTTGTTTGAGTAAGAGAGTGAATGGTTCTGAGTGTTTAGGAA
GGATTTGCTTGCTTGCAGCAGAAGTTCTAGGAAAAGCAGGCACCTCCCAAATATCTTGAGGACACTGGCAGCCTTATGGTGACTAAATCC
ACACTTTCTTTAAAGAGATGCAGATGAATTACTTTTCTGTTAATATATAGAAAAATACACAGGAGAACATGCAGATACATGTAAATATCT
ACATACAGGGATATTTGTATGTGTGGTTGTGAAACCCATACACAAGTGGATTTGGCCATCTTTGGGCAGTGAGGTCAAATGTGAATATGT
GTAAAAGTGCTTTTCAGAACTGCATTACTATGAGAAAACATCAAAACTGCTGTAGTTTTCCATTTCTACTGTATTTCAGTTGCAACCTAT
TTTTAATAAACTTTGTATGTATTTAAGTGTATTTGCTATTGTTTTGAAAGTGCTGACAAAGTTTATATTTGTAACATCAGCCTTCCTCGC

>79232_79232_3_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000366806_length(amino acids)=1307AA_BP=509
MLLGRANSPPYNSVVRTLPPATLLLRRAGWESFWSCQSRSPWPPRPEVRAPAKGPRGVAGAAGACSAGARLGDAAGGDPASGQAARGCGA
RAPRGLGRTARARDTAMEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNIDDLAQQYADYYNTCF
SDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSAVSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKG
IMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSSNCNSREQSDDETEE
SVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVLDERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTW
GAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQ
LLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLP
WAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASK
SQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSK
SVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQR
WYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSS
GDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRL
EAERRARLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGLCRPP
LPRDYEPPSPSPAPGAPPPPPQRNASYLKTQVLSPDSLFTAKFVAYNEEEEEEDCSLAGPNSYPGSTGAAVGAHDACRDAKEKRSKSQDA

--------------------------------------------------------------
>79232_79232_4_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000392108_length(transcript)=5276nt_BP=1684nt
ATTTTGAAGAGAGGGGTCCCGGGGAGCTCCCTCCAAGATCTAGAGGCTCCGCGGCCACCCCTGCCGGGTCCTGCCAAGACTTGCTAGAAG
GAACGAGTCGCGTGCCTTAGTTAGTTGGTTCCCGTCACAGGAAGAAACGCCTTTGCAGTGGGTTTAATTGCTTCTGGGCCGAGCGAATTC
CCCGCCGTACAACTCAGTGGTGCGGACTTTGCCTCCTGCTACCCTGTTGCTGCGCCGAGCGGGGTGGGAAAGTTTCTGGAGTTGTCAGTC
GCGCAGCCCGTGGCCACCTAGACCCGAGGTGCGGGCGCCTGCGAAGGGCCCCCGCGGGGTGGCCGGGGCCGCCGGGGCATGCAGCGCGGG
GGCGCGGCTCGGTGACGCCGCGGGCGGGGACCCGGCATCCGGGCAGGCTGCGCGCGGGTGCGGGGCGAGGGCGCCGCGGGGACTGGGACG
CACGGCCCGCGCGCGGGACACGGCCATGGAGGACGCGGGAGCAGCTGGCCCGGGGCCGGAGCCTGAGCCCGAGCCCGAGCCGGAGCCCGA
GCCCGCGCCGGAGCCGGAACCGGAGCCCAAGCCGGGTGCTGGCACATCCGAGGCGTTCTCCCGACTCTGGACCGACGTGATGGGTATCCT
GGACGGTTCACTGGGAAACATCGATGACCTGGCGCAGCAGTATGCAGATTATTACAACACCTGTTTCTCCGACGTGTGCGAGAGGATGGA
GGAGCTGCGGAAACGGCGGGTTTCCCAGGACCTGGAAGTGGAGAAACCCGATGCTAGCCCCACGTCACTTCAGCTGCGGTCCCAGATCGA
AGAGTCGCTTGGCTTCTGTAGCGCCGTGTCAACCCCAGAAGTGGAAAGAAAGAACCCTCTTCATAAATCAAACTCAGAAGACAGCTCTGT
AGGAAAAGGAGACTGGAAGAAGAAAAATAAGTATTTCTGGCAGAACTTCCGAAAGAACCAGAAAGGAATAATGAGACAGACTTCAAAAGG
AGAAGACGTTGGTTATGTTGCCAGTGAAATAACGATGAGCGATGAGGAGCGGATTCAGCTAATGATGATGGTCAAAGAAAAGATGATCAC
AATTGAGGAAGCACTTGCTAGGCTCAAGGAATACGAGGCCCAGCACCGGCAGTCGGCTGCCCTGGACCCTGCTGACTGGCCAGATGGTTC
TTACCCAACGTTTGATGGCTCATCAAACTGCAATTCAAGAGAACAATCGGATGATGAGACTGAGGAGTCGGTGAAGTTTAAGAGGTTACA
CAAGCTGGTAAACTCCACTCGCAGAGTCAGAAAGAAACTAATTAGGGTGGAAGAAATGAAAAAACCCAGCACTGAAGGTGGGGAGGAGCA
CGTGTTTGAGAATTCGCCGGTCCTGGATGAACGGTCCGCCCTCTACTCTGGCGTGCACAAGAAGCCCCTTTTCTTTGATGGCTCTCCTGA
GAAACCTCCCGAAGATGACTCAGACTCTCTCACCACGTCTCCATCCTCCAGCAGCCTGGACACCTGGGGGGCTGGCCGGAAGTTGGTCAA
AACCTTCAGCAAAGGAGAGAGCCGGGGCCTGATTAAGCCCCCCAAGAAGATGGGGACATTCTTCTCCTACCCAGAAGAAGAAAAGGCCCA
GAAAGTGTCCCGCTCCCTCACCGAGGGGGAGATGAAGAAGGGTCTCGGGTCCCTAAGCCACGGGGGTGCTGGTCAAGATAAACTAGGAAT
CTATGTGAAGTCGGTTGTGAAAGGAGGTGCTGCAGATGTGGATGGACGTCTAGCTGCAGGTGATCAGCTCCTCAGTGTGGATGGACGAAG
TCTGGTTGGACTCTCTCAGGAAAGGGCGGCAGAACTCATGACAAGAACAAGCTCTGTGGTGACACTGGAAGTAGCAAAGCAGGGTGCCAT
CTACCACGGTCTGGCCACCCTTCTCAATCAGCCATCCCCCATGATGCAGAGAATTTCAGATCGTCGTGGCTCAGGTAAACCCCGACCAAA
GAGTGAAGGCTTTGAGCTCTATAATAATTCAACTCAAAATGGGTCTCCTGAGAGTCCTCAGCTGCCTTGGGCAGAATATAGTGAACCAAA
GAAATTGCCTGGTGATGACAGACTGATGAAAAATAGAGCTGATCACCGTTCCAGCCCCAACGTAGCAAATCAGCCTCCTAGTCCTGGAGG
GAAAAGTGCATATGCCTCTGGAACAACAGCGAAGATAACATCTGTCTCTACTGGAAACCTCTGCACTGAGGAGCAGACGCCTCCGCCTAG
ACCTGAAGCCTACCCCATCCCCACTCAGACGTACACCAGAGAGTATTTTACCTTCCCAGCTTCCAAATCCCAGGATCGGATGGCTCCTCC
TCAGAACCAGTGGCCAAATTATGAGGAAAAGCCACATATGCACACAGATAGTAATCATTCCAGTATTGCAATTCAGCGTGTTACACGTTC
CCAAGAAGAACTTCGAGAAGATAAAGCTTACCAACTTGAGCGGCATCGAATAGAGGCAGCTATGGACCGAAAGTCTGATAGTGATATGTG
GATAAATCAGAGCTCCTCACTGGACTCCAGTACCTCTAGCCAGGAGCATCTGAACCATTCCTCTAAGTCGGTCACCCCTGCTTCCACACT
GACCAAAAGTGGCCCTGGCCGTTGGAAAACACCAGCAGCCATACCGGCCACCCCTGTGGCCGTCTCCCAGCCAATCCGAACAGACCTGCC
TCCGCCACCCCCGCCACCTCCAGTCCACTATGCCGGTGATTTCGATGGAATGTCCATGGATTTGCCTCTCCCACCACCCCCTTCCGCCAA
CCAGATAGGGCTGCCGTCTGCGCAGGTGGCTGCTGCTGAACGGAGAAAGAGAGAAGAACATCAGCGTTGGTATGAGAAGGAGAAGGCCCG
CCTGGAGGAGGAGCGGGAGAGGAAGCGGAGAGAGCAGGAGAGGAAGTTGGGCCAGATGCGCACTCAGTCCTTAAACCCTGCTCCGTTTTC
TCCCCTGACTGCACAGCAGATGAAGCCCGAAAAGCCTTCCACACTCCAGCGGCCACAGGAAACAGTCATTCGGGAGCTGCAGCCTCAGCA
GCAGCCCCGCACGATCGAGCGCAGAGACTTGCAGTACATTACAGTCAGCAAAGAGGAGCTTTCCTCGGGGGACAGTCTGTCCCCCGACCC
GTGGAAGCGGGACGCCAAGGAGAAGCTGGAGAAGCAGCAGCAGATGCACATCGTGGACATGCTGAGCAAGGAGATCCAGGAGCTCCAGAG
CAAACCGGACCGCAGCGCCGAGGAGAGCGACCGGCTGCGCAAGCTCATGCTGGAGTGGCAGTTCCAGAAGAGACTCCAGGAGTCGAAGCA
GAAGGACGAAGATGACGAGGAGGAGGAGGACGATGATGTGGACACCATGCTGATCATGCAGCGCCTGGAGGCTGAACGAAGAGCGAGGGA
CGAGGAGCGGAGGCGGCAGCAGCAGTTAGAAGAGATGCGCAAGCGGGAAGCGGAAGACCGAGCGAGGCAAGAGGAAGAGCGCCGGCGGCA
GGAGGAGGAGCGAACAAAACGAGACGCTGAAGAAAAGGTTATGGTCCTTTAAGGGCAGCTAGAATTTTACCAAGTTAGCCTGAACGTAAT
CGATTGGCTGGGGCAGAGCGGGCTGGAAGTTCTGTGTTTCTTAAGAAGCACGAGGCAGAGCAGGGCCTGGCTCCCCCAGCTTTGTGATTG
GACCTGCAACTTTACCCCATCTGGCCCACCTACCTCTCTTCTGGACTGTCTCCAGATCCCCTTATCTGCCAAGTTTTGTCTCCTTCAAAC
TTCTGAACTCTTGGGCGTGTGTAGCAGTGAGCCTCTTTGCAAAGGGTTCGTTTCCTCGGGCACTCATCTTTACTGAACATGGCCCAGCTT
GTCATTGTGAAGGTGACATTGGTTCAGTGATTGCTTAAATGGCATGTGGACCGTGGGAAGCAGTAGGAGCGTAGTAAGACAGTTGGCTGC
CATTCAACATTTCAAATAGATGGTTTACTCAAATCACTCACTTCTGGTTGATGGTAAAGAGAGCAGATGGCTTAGAAAACATGATACAGG
AAAATTTAGTATGTAATCCAGTAAATATCCTAAGTTATTTATTTTCATGTGTGTGTGTGTGTTTAAATCAAGTAACCCTTTTAATTGAAT
TTTAAAATGACAGCGAATTTTGACATTCTGAGAAATGGGGATTTTGAGATGTTTCTCTCCATATCTCCCTTTGTCCTGTGTGTGTGGCCG
ACGCCCTCTGGATGAAGAGGCTGTAGCCGTTGAGCTCCCTGTGGGGGCCTGTTTCATCCCGAGGGGACTGCGTGTTGCTCTGTGTGGTTT
GAGAGAAGCTGCTCTTCTCTGTTACTTCCCTTCTATGAAGGTAGAAGCTTTCAGTGTTACAACTTCTGATGGCGGAAAATTTAGTTTTTA
TTAATAATTCCTTCTTGGATAGTCTAGTGAACTATATTAATAGAACAGTGTACTGTTCACAGAAAAGAACTTGTAGGGAGTTTTTTGTAG
TGATATGCTCTATTAGGATACAGAACAATCTAAGAGTAAGCTTGATAGACATGATGTGACTTCACTTAAATGGAGTAGAGTGAATAATGT
AAGGACACTCACCTCTGTTGAAATTGGTGATTTCTGCATTTTGTAGACCTTTGCCCTCTAAGTTTATCATCATATTATCTGTTGAATCTG
AACAGCATTTGAAGTCCTCTCAAAGAGTTTGAGCTTTCAGGATTAGGTTCCCCTGTGAGTCTTTCACTTGTGTAATGGTAAGTCAACATT
GATGATCTTTCTAAGGAAATCAGATTTACAAAATGCTGAGCCGCTTGATGTCTAAGTGTTGGTGGTTTTTGCTGTTGCTTTGCTGTTCCA
TGAAAGCGCTCCCTGGCTGCTTGGAGGGCTGTGCTTTTCCAGGTCAGTGCCAGCTTGGCTGTCCCAGGCCGTGCACAGTGCCCATTGCTA
TAGCTGGGCCCAGTCCTGGCCACGCCGGAGCCTCGGCGGGGGCAGCTGGGTTGTCACGGCAGCACAGTGCACATGCAGAGAGGACCAGGC
CATGTTTTTCCTGTGCTGAGAAACTCTTGGGTTATTTAATTTTTCCAATGTGTTTTCATAACTCATGATTATTTGAAATACACTTGTGTT
AGTAACTGCTTCTATAATTAAGTGGTCACTGTAAAAAGGCGAATAACCTATTTTTATATCAGAATGTCCAAAACTCATGGGTTTGCTTTG

>79232_79232_4_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000392108_length(amino acids)=1134AA_BP=509
MLLGRANSPPYNSVVRTLPPATLLLRRAGWESFWSCQSRSPWPPRPEVRAPAKGPRGVAGAAGACSAGARLGDAAGGDPASGQAARGCGA
RAPRGLGRTARARDTAMEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNIDDLAQQYADYYNTCF
SDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSAVSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKG
IMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSSNCNSREQSDDETEE
SVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVLDERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTW
GAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQ
LLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLP
WAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASK
SQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSK
SVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQR
WYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSS
GDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRL

--------------------------------------------------------------
>79232_79232_5_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000392112_length(transcript)=5973nt_BP=1684nt
ATTTTGAAGAGAGGGGTCCCGGGGAGCTCCCTCCAAGATCTAGAGGCTCCGCGGCCACCCCTGCCGGGTCCTGCCAAGACTTGCTAGAAG
GAACGAGTCGCGTGCCTTAGTTAGTTGGTTCCCGTCACAGGAAGAAACGCCTTTGCAGTGGGTTTAATTGCTTCTGGGCCGAGCGAATTC
CCCGCCGTACAACTCAGTGGTGCGGACTTTGCCTCCTGCTACCCTGTTGCTGCGCCGAGCGGGGTGGGAAAGTTTCTGGAGTTGTCAGTC
GCGCAGCCCGTGGCCACCTAGACCCGAGGTGCGGGCGCCTGCGAAGGGCCCCCGCGGGGTGGCCGGGGCCGCCGGGGCATGCAGCGCGGG
GGCGCGGCTCGGTGACGCCGCGGGCGGGGACCCGGCATCCGGGCAGGCTGCGCGCGGGTGCGGGGCGAGGGCGCCGCGGGGACTGGGACG
CACGGCCCGCGCGCGGGACACGGCCATGGAGGACGCGGGAGCAGCTGGCCCGGGGCCGGAGCCTGAGCCCGAGCCCGAGCCGGAGCCCGA
GCCCGCGCCGGAGCCGGAACCGGAGCCCAAGCCGGGTGCTGGCACATCCGAGGCGTTCTCCCGACTCTGGACCGACGTGATGGGTATCCT
GGACGGTTCACTGGGAAACATCGATGACCTGGCGCAGCAGTATGCAGATTATTACAACACCTGTTTCTCCGACGTGTGCGAGAGGATGGA
GGAGCTGCGGAAACGGCGGGTTTCCCAGGACCTGGAAGTGGAGAAACCCGATGCTAGCCCCACGTCACTTCAGCTGCGGTCCCAGATCGA
AGAGTCGCTTGGCTTCTGTAGCGCCGTGTCAACCCCAGAAGTGGAAAGAAAGAACCCTCTTCATAAATCAAACTCAGAAGACAGCTCTGT
AGGAAAAGGAGACTGGAAGAAGAAAAATAAGTATTTCTGGCAGAACTTCCGAAAGAACCAGAAAGGAATAATGAGACAGACTTCAAAAGG
AGAAGACGTTGGTTATGTTGCCAGTGAAATAACGATGAGCGATGAGGAGCGGATTCAGCTAATGATGATGGTCAAAGAAAAGATGATCAC
AATTGAGGAAGCACTTGCTAGGCTCAAGGAATACGAGGCCCAGCACCGGCAGTCGGCTGCCCTGGACCCTGCTGACTGGCCAGATGGTTC
TTACCCAACGTTTGATGGCTCATCAAACTGCAATTCAAGAGAACAATCGGATGATGAGACTGAGGAGTCGGTGAAGTTTAAGAGGTTACA
CAAGCTGGTAAACTCCACTCGCAGAGTCAGAAAGAAACTAATTAGGGTGGAAGAAATGAAAAAACCCAGCACTGAAGGTGGGGAGGAGCA
CGTGTTTGAGAATTCGCCGGTCCTGGATGAACGGTCCGCCCTCTACTCTGGCGTGCACAAGAAGCCCCTTTTCTTTGATGGCTCTCCTGA
GAAACCTCCCGAAGATGACTCAGACTCTCTCACCACGTCTCCATCCTCCAGCAGCCTGGACACCTGGGGGGCTGGCCGGAAGTTGGTCAA
AACCTTCAGCAAAGGAGAGAGCCGGGGCCTGATTAAGCCCCCCAAGAAGATGGGGACATTCTTCTCCTACCCAGAAGAAGAAAAGGCCCA
GAAAGTGTCCCGCTCCCTCACCGAGGGGGAGATGAAGAAGGGTCTCGGGTCCCTAAGCCACGGGGGTGCTGGTCAAGATAAACTAGGAAT
CTATGTGAAGTCGGTTGTGAAAGGAGGTGCTGCAGATGATGGACGTCTAGCTGCAGGTGATCAGCTCCTCAGTGTGGATGGACGAAGTCT
GGTTGGACTCTCTCAGGAAAGGGCGGCAGAACTCATGACAAGAACAAGCTCTGTGGTGACACTGGAAGTAGCAAAGCAGGGTGCCATCTA
CCACGGTCTGGCCACCCTTCTCAATCAGCCATCCCCCATGATGCAGAGAATTTCAGATCGTCGTGGCTCAGGTAAACCCCGACCAAAGAG
TGAAGGCTTTGAGCTCTATAATAATTCAACTCAAAATGGGTCTCCTGAGAGTCCTCAGCTGCCTTGGGCAGAATATAGTGAACCAAAGAA
ATTGCCTGGTGATGACAGACTGATGAAAAATAGAGCTGATCACCGTTCCAGCCCCAACGTAGCAAATCAGCCTCCTAGTCCTGGAGGGAA
AAGTGCATATGCCTCTGGAACAACAGCGAAGATAACATCTGTCTCTACTGGAAACCTCTGCACTGAGGAGCAGACGCCTCCGCCTAGACC
TGAAGCCTACCCCATCCCCACTCAGACGTACACCAGAGAGTATTTTACCTTCCCAGCTTCCAAATCCCAGGATCGGATGGCTCCTCCTCA
GAACCAGTGGCCAAATTATGAGGAAAAGCCACATATGCACACAGATAGTAATCATTCCAGTATTGCAATTCAGCGTGTTACACGTTCCCA
AGAAGAACTTCGAGAAGATAAAGCTTACCAACTTGAGCGGCATCGAATAGAGGCAGCTATGGACCGAAAGTCTGATAGTGATATGTGGAT
AAATCAGAGCTCCTCACTGGACTCCAGTACCTCTAGCCAGGAGCATCTGAACCATTCCTCTAAGTCGGTCACCCCTGCTTCCACACTGAC
CAAAAGTGGCCCTGGCCGTTGGAAAACACCAGCAGCCATACCGGCCACCCCTGTGGCCGTCTCCCAGCCAATCCGAACAGACCTGCCTCC
GCCACCCCCGCCACCTCCAGTCCACTATGCCGGTGATTTCGATGGAATGTCCATGGATTTGCCTCTCCCACCACCCCCTTCCGCCAACCA
GATAGGGCTGCCGTCTGCGCAGGTGGCTGCTGCTGAACGGAGAAAGAGAGAAGAACATCAGCGTTGGTATGAGAAGGAGAAGGCCCGCCT
GGAGGAGGAGCGGGAGAGGAAGCGGAGAGAGCAGGAGAGGAAGTTGGGCCAGATGCGCACTCAGTCCTTAAACCCTGCTCCGTTTTCTCC
CCTGACTGCACAGCAGATGAAGCCCGAAAAGCCTTCCACACTCCAGCGGCCACAGGAAACAGTCATTCGGGAGCTGCAGCCTCAGCAGCA
GCCCCGCACGATCGAGCGCAGAGACTTGCAGTACATTACAGTCAGCAAAGAGGAGCTTTCCTCGGGGGACAGTCTGTCCCCCGACCCGTG
GAAGCGGGACGCCAAGGAGAAGCTGGAGAAGCAGCAGCAGATGCACATCGTGGACATGCTGAGCAAGGAGATCCAGGAGCTCCAGAGCAA
ACCGGACCGCAGCGCCGAGGAGAGCGACCGGCTGCGCAAGCTCATGCTGGAGTGGCAGTTCCAGAAGAGACTCCAGGAGTCGAAGCAGAA
GGACGAAGATGACGAGGAGGAGGAGGACGATGATGTGGACACCATGCTGATCATGCAGCGCCTGGAGGCTGAACGAAGAGCGAGGTTGCA
GGACGAGGAGCGGAGGCGGCAGCAGCAGTTAGAAGAGATGCGCAAGCGGGAAGCGGAAGACCGAGCGAGGCAAGAGGAAGAGCGCCGGCG
GCAGGAGGAGGAGCGAACAAAACGAGACGCTGAAGAAAAGAGGCGACAGGAAGAAGGGTATTACAGCCGCCTGGAAGCCGAGAGGCGCAG
ACAGCACGACGAGGCGGCGCGCAGGTTGCTGGAGCCCGAGGCGCCCGGACCAAACTCTTACCCAGGATCTACTGGAGCAGCTGTTGGAGC
CCATGACGCCTGTCGGGATGCAAAAGAGAAGCGCTCTAAAAGCCAAGATGCAGATTCACCTGGAAGTTCTGGGGCCCCTGAAAACTTGAC
ATTCAAGGAACGCCAGCGTCTTTTTTCACAAGGTCAAGATGTATCCAATAAAGTGAAAGCTTCTCGTAAATTAACAGAACTGGAGAATGA
ACTGAACACAAAGTGAAAGAAAATGAGGAGAACACTTTGTATTTACCCCAAAATCTTTTCAGTTGTGGGTTTGTAGGTGCGAGTTTGAAG
AGGAAAAGAGGAAGGGGGTTATATTTCTAAGTGATTTACAATTTCTGTTTCTAAAATTGTTGGGATTTAGAAATGTTTCAATTCCAAGAA
ATTTTATTTTACTTTACCATGAGATTGCCATTTATGTAATTTAAACACTGTCTAGTTTCTTAATTATCTAACTCACACGAGGGTAAGTTT
TTTGTTGGTTTCTTTTTTGGAGTCCTGAGTTCAAAGGGGACAGAACTAAGGGCAGGAGAAGAGAATGGATGTGTCTTCTCTCCCATCTTC
CCCTCATCATCGACCGAGGAGCACAAAGAAGTTCTGTTTCTGTTTTTTTCAGAAACTTTATTTTAGCTGTCAAGCAGAGAATAGCTTGAA
CTATTCAGACTATTGTTGGCACTGTTTAGTAGTGACCACACGCTCTTCTACCCGGGAAGGAACATATGACGACATGCTCCTCCCATGTCC
CCTGATGGTGTCTGTTCCCACAATATCCTTCTAGTCTGCATCGTGAAGTGGCTTAGGCCAAAGCTTCCTGTGTGATGACGCACGTCCGAG
ACTGTTCCATCTCATTCCTCGCAAATTTGAGCTCTTCTGATCAATTCTAAATATTTGATTAATTTTAATTCTGAAAGAAAATTTTGAGGA
TTTAAGCTTAGGGGATTTTATTTTTATAAATACCAGATTATTGTTAGACTTAATAAATCACTGTTAAATTTAAAGATGACAGTTACCTTG
GAAAGTTCACTAATACTTCGCTCCAAGGCGTCTGTAAAAGAAGATATCTTTATTGGAGCAATGTTCATGTGACTGGGAATGACAGAAGAA
TGGGAGATGAGTAGGGACCCCTCAAGCACAGCTGTCACTCAGAAATTTTAAATTTGAAAAAGAAATCGATTTTCATCTGTATGCCGTCAA
GGAAGGAATTCAGTTACAGGGCATCTGTAACTTAAATATTGTAAGAATAACTCATATGGAAGTTCAAGCTATTTTTATACTATAATAGAG
TTATTTAATTTTAATTTGTTGAATTATTAGTTACCACTGTCATTTCTTCAGCTATGGATATGTGGCTGATGTTGGGGAGACGGACCTCAG
TGTGTTTTATATTGTCTGGTGTTAAGATGATAAATTACTTTGTGATTACAAGCAAATTTTCTATTTGACAAAGCCCTTGGTGGAGTCCAA
ATGATTTTTCTGTACCATATTGTTCTCTTACACATACGTATGTTAGGAAAATAGGCACACTTTCAAAGAGAATGTTCTCTTACACATACG
TATGTTAGGAAAATAGACACATTTTCAAAGAGAATGTTCTCTTACATATGTTAGGAAAATAGGCACACTTTCAAAGAGAGGTATAGGGGC
TTTTTACTGCCTTCGAAATCACTTTTAATAAAAGTTGTATGATAAATCATTAAAAATGCGAGTGTAAATATTTTTTTTTACCTCTATCAG
GGTTTTTATTTGAAAGTGTGCTCTTACCATTTCCTTGTTTGAGTAAGAGAGTGAATGGTTCTGAGTGTTTAGGAAGGATTTGCTTGCTTG
CAGCAGAAGTTCTAGGAAAAGCAGGCACCTCCCAAATATCTTGAGGACACTGGCAGCCTTATGGTGACTAAATCCACACTTTCTTTAAAG
AGATGCAGATGAATTACTTTTCTGTTAATATATAGAAAAATACACAGGAGAACATGCAGATACATGTAAATATCTACATACAGGGATATT
TGTATGTGTGGTTGTGAAACCCATACACAAGTGGATTTGGCCATCTTTGGGCAGTGAGGTCAAATGTGAATATGTGTAAAAGTGCTTTTC
AGAACTGCATTACTATGAGAAAACATCAAAACTGCTGTAGTTTTCCATTTCTACTGTATTTCAGTTGCAACCTATTTTTAATAAACTTTG
TATGTATTTAAGTGTATTTGCTATTGTTTTGAAAGTGCTGACAAAGTTTATATTTGTAACATCAGCCTTCCTCGCCCATCTCTTTCCATC

>79232_79232_5_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000392112_length(amino acids)=1242AA_BP=509
MLLGRANSPPYNSVVRTLPPATLLLRRAGWESFWSCQSRSPWPPRPEVRAPAKGPRGVAGAAGACSAGARLGDAAGGDPASGQAARGCGA
RAPRGLGRTARARDTAMEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNIDDLAQQYADYYNTCF
SDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSAVSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKG
IMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSSNCNSREQSDDETEE
SVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVLDERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTW
GAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGGAGQDKLGIYVKSVVKGGAADDGRLAAGDQL
LSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLPW
AEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKS
QDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSKS
VTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRW
YEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSG
DSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLE
AERRARLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGPNSYPG

--------------------------------------------------------------
>79232_79232_6_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000400822_length(transcript)=6202nt_BP=1684nt
ATTTTGAAGAGAGGGGTCCCGGGGAGCTCCCTCCAAGATCTAGAGGCTCCGCGGCCACCCCTGCCGGGTCCTGCCAAGACTTGCTAGAAG
GAACGAGTCGCGTGCCTTAGTTAGTTGGTTCCCGTCACAGGAAGAAACGCCTTTGCAGTGGGTTTAATTGCTTCTGGGCCGAGCGAATTC
CCCGCCGTACAACTCAGTGGTGCGGACTTTGCCTCCTGCTACCCTGTTGCTGCGCCGAGCGGGGTGGGAAAGTTTCTGGAGTTGTCAGTC
GCGCAGCCCGTGGCCACCTAGACCCGAGGTGCGGGCGCCTGCGAAGGGCCCCCGCGGGGTGGCCGGGGCCGCCGGGGCATGCAGCGCGGG
GGCGCGGCTCGGTGACGCCGCGGGCGGGGACCCGGCATCCGGGCAGGCTGCGCGCGGGTGCGGGGCGAGGGCGCCGCGGGGACTGGGACG
CACGGCCCGCGCGCGGGACACGGCCATGGAGGACGCGGGAGCAGCTGGCCCGGGGCCGGAGCCTGAGCCCGAGCCCGAGCCGGAGCCCGA
GCCCGCGCCGGAGCCGGAACCGGAGCCCAAGCCGGGTGCTGGCACATCCGAGGCGTTCTCCCGACTCTGGACCGACGTGATGGGTATCCT
GGACGGTTCACTGGGAAACATCGATGACCTGGCGCAGCAGTATGCAGATTATTACAACACCTGTTTCTCCGACGTGTGCGAGAGGATGGA
GGAGCTGCGGAAACGGCGGGTTTCCCAGGACCTGGAAGTGGAGAAACCCGATGCTAGCCCCACGTCACTTCAGCTGCGGTCCCAGATCGA
AGAGTCGCTTGGCTTCTGTAGCGCCGTGTCAACCCCAGAAGTGGAAAGAAAGAACCCTCTTCATAAATCAAACTCAGAAGACAGCTCTGT
AGGAAAAGGAGACTGGAAGAAGAAAAATAAGTATTTCTGGCAGAACTTCCGAAAGAACCAGAAAGGAATAATGAGACAGACTTCAAAAGG
AGAAGACGTTGGTTATGTTGCCAGTGAAATAACGATGAGCGATGAGGAGCGGATTCAGCTAATGATGATGGTCAAAGAAAAGATGATCAC
AATTGAGGAAGCACTTGCTAGGCTCAAGGAATACGAGGCCCAGCACCGGCAGTCGGCTGCCCTGGACCCTGCTGACTGGCCAGATGGTTC
TTACCCAACGTTTGATGGCTCATCAAACTGCAATTCAAGAGAACAATCGGATGATGAGACTGAGGAGTCGGTGAAGTTTAAGAGGTTACA
CAAGCTGGTAAACTCCACTCGCAGAGTCAGAAAGAAACTAATTAGGGTGGAAGAAATGAAAAAACCCAGCACTGAAGGTGGGGAGGAGCA
CGTGTTTGAGAATTCGCCGGTCCTGGATGAACGGTCCGCCCTCTACTCTGGCGTGCACAAGAAGCCCCTTTTCTTTGATGGCTCTCCTGA
GAAACCTCCCGAAGATGACTCAGACTCTCTCACCACGTCTCCATCCTCCAGCAGCCTGGACACCTGGGGGGCTGGCCGGAAGTTGGTCAA
AACCTTCAGCAAAGGAGAGAGCCGGGGCCTGATTAAGCCCCCCAAGAAGATGGGGACATTCTTCTCCTACCCAGAAGAAGAAAAGGCCCA
GAAAGTGTCCCGCTCCCTCACCGAGGGGGAGATGAAGAAGGGTCTCGGGTCCCTAAGCCACGGGGGTGCTGGTCAAGATAAACTAGGAAT
CTATGTGAAGTCGGTTGTGAAAGGAGGTGCTGCAGATGTGGATGGACGTCTAGCTGCAGGTGATCAGCTCCTCAGTGTGGATGGACGAAG
TCTGGTTGGACTCTCTCAGGAAAGGGCGGCAGAACTCATGACAAGAACAAGCTCTGTGGTGACACTGGAAGTAGCAAAGCAGGGTGCCAT
CTACCACGGTCTGGCCACCCTTCTCAATCAGCCATCCCCCATGATGCAGAGAATTTCAGATCGTCGTGGCTCAGGTAAACCCCGACCAAA
GAGTGAAGGCTTTGAGCTCTATAATAATTCAACTCAAAATGGGTCTCCTGAGAGTCCTCAGCTGCCTTGGGCAGAATATAGTGAACCAAA
GAAATTGCCTGGTGATGACAGACTGATGAAAAATAGAGCTGATCACCGTTCCAGCCCCAACGTAGCAAATCAGCCTCCTAGTCCTGGAGG
GAAAAGTGCATATGCCTCTGGAACAACAGCGAAGATAACATCTGTCTCTACTGGAAACCTCTGCACTGAGGAGCAGACGCCTCCGCCTAG
ACCTGAAGCCTACCCCATCCCCACTCAGACGTACACCAGAGAGTATTTTACCTTCCCAGCTTCCAAATCCCAGGATCGGATGGCTCCTCC
TCAGAACCAGTGGCCAAATTATGAGGAAAAGCCACATATGCACACAGATAGTAATCATTCCAGTATTGCAATTCAGCGTGTTACACGTTC
CCAAGAAGAACTTCGAGAAGATAAAGCTTACCAACTTGAGCGGCATCGAATAGAGGCAGCTATGGACCGAAAGTCTGATAGTGATATGTG
GATAAATCAGAGCTCCTCACTGGACTCCAGTACCTCTAGCCAGGAGCATCTGAACCATTCCTCTAAGTCGGTCACCCCTGCTTCCACACT
GACCAAAAGTGGCCCTGGCCGTTGGAAAACACCAGCAGCCATACCGGCCACCCCTGTGGCCGTCTCCCAGCCAATCCGAACAGACCTGCC
TCCGCCACCCCCGCCACCTCCAGTCCACTATGCCGGTGATTTCGATGGAATGTCCATGGATTTGCCTCTCCCACCACCCCCTTCCGCCAA
CCAGATAGGGCTGCCGTCTGCGCAGGTGGCTGCTGCTGAACGGAGAAAGAGAGAAGAACATCAGCGTTGGTATGAGAAGGAGAAGGCCCG
CCTGGAGGAGGAGCGGGAGAGGAAGCGGAGAGAGCAGGAGAGGAAGTTGGGCCAGATGCGCACTCAGTCCTTAAACCCTGCTCCGTTTTC
TCCCCTGACTGCACAGCAGATGAAGCCCGAAAAGCCTTCCACACTCCAGCGGCCACAGGAAACAGTCATTCGGGAGCTGCAGCCTCAGCA
GCAGCCCCGCACGATCGAGCGCAGAGACTTGCAGTACATTACAGTCAGCAAAGAGGAGCTTTCCTCGGGGGACAGTCTGTCCCCCGACCC
GTGGAAGCGGGACGCCAAGGAGAAGCTGGAGAAGCAGCAGCAGATGCACATCGTGGACATGCTGAGCAAGGAGATCCAGGAGCTCCAGAG
CAAACCGGACCGCAGCGCCGAGGAGAGCGACCGGCTGCGCAAGCTCATGCTGGAGTGGCAGTTCCAGAAGAGACTCCAGGAGTCGAAGCA
GAAGGACGAAGATGACGAGGAGGAGGAGGACGATGATGTGGACACCATGCTGATCATGCAGCGCCTGGAGGCTGAACGAAGAGCGAGGAC
TGCTATGCCAGCAATCTCTGTTCTAGATTTGTTGCAGGACGAGGAGCGGAGGCGGCAGCAGCAGTTAGAAGAGATGCGCAAGCGGGAAGC
GGAAGACCGAGCGAGGCAAGAGGAAGAGCGCCGGCGGCAGGAGGAGGAGCGAACAAAACGAGACGCTGAAGAAAAGAGGCGACAGGAAGA
AGGGTATTACAGCCGCCTGGAAGCCGAGAGGCGCAGACAGCACGACGAGGCGGCGCGCAGGTTGCTGGAGCCCGAGGCGCCCGGTCTGTG
CCGCCCTCCGCTTCCCCGGGACTACGAGCCCCCGTCCCCGTCCCCCGCGCCCGGCGCCCCTCCTCCCCCGCCTCAGCGAAACGCCTCCTA
CCTCAAAACACAGGTCCTCTCCCCCGACTCGCTGTTCACTGCCAAGTTTGTTGCATACAATGAGGAGGAGGAGGAGGAGGACTGCAGCCT
AGCAGGACCAAACTCTTACCCAGGATCTACTGGAGCAGCTGTTGGAGCCCATGACGCCTGTCGGGATGCAAAAGAGAAGCGCTCTAAAAG
CCAAGATGCAGATTCACCTGGAAGTTCTGGGGCCCCTGAAAACTTGACATTCAAGGAACGCCAGCGTCTTTTTTCACAAGGTCAAGATGT
ATCCAATAAAGTGAAAGCTTCTCGTAAATTAACAGAACTGGAGAATGAACTGAACACAAAGTGAAAGAAAATGAGGAGAACACTTTGTAT
TTACCCCAAAATCTTTTCAGTTGTGGGTTTGTAGGTGCGAGTTTGAAGAGGAAAAGAGGAAGGGGGTTATATTTCTAAGTGATTTACAAT
TTCTGTTTCTAAAATTGTTGGGATTTAGAAATGTTTCAATTCCAAGAAATTTTATTTTACTTTACCATGAGATTGCCATTTATGTAATTT
AAACACTGTCTAGTTTCTTAATTATCTAACTCACACGAGGGTAAGTTTTTTGTTGGTTTCTTTTTTGGAGTCCTGAGTTCAAAGGGGACA
GAACTAAGGGCAGGAGAAGAGAATGGATGTGTCTTCTCTCCCATCTTCCCCTCATCATCGACCGAGGAGCACAAAGAAGTTCTGTTTCTG
TTTTTTTCAGAAACTTTATTTTAGCTGTCAAGCAGAGAATAGCTTGAACTATTCAGACTATTGTTGGCACTGTTTAGTAGTGACCACACG
CTCTTCTACCCGGGAAGGAACATATGACGACATGCTCCTCCCATGTCCCCTGATGGTGTCTGTTCCCACAATATCCTTCTAGTCTGCATC
GTGAAGTGGCTTAGGCCAAAGCTTCCTGTGTGATGACGCACGTCCGAGACTGTTCCATCTCATTCCTCGCAAATTTGAGCTCTTCTGATC
AATTCTAAATATTTGATTAATTTTAATTCTGAAAGAAAATTTTGAGGATTTAAGCTTAGGGGATTTTATTTTTATAAATACCAGATTATT
GTTAGACTTAATAAATCACTGTTAAATTTAAAGATGACAGTTACCTTGGAAAGTTCACTAATACTTCGCTCCAAGGCGTCTGTAAAAGAA
GATATCTTTATTGGAGCAATGTTCATGTGACTGGGAATGACAGAAGAATGGGAGATGAGTAGGGACCCCTCAAGCACAGCTGTCACTCAG
AAATTTTAAATTTGAAAAAGAAATCGATTTTCATCTGTATGCCGTCAAGGAAGGAATTCAGTTACAGGGCATCTGTAACTTAAATATTGT
AAGAATAACTCATATGGAAGTTCAAGCTATTTTTATACTATAATAGAGTTATTTAATTTTAATTTGTTGAATTATTAGTTACCACTGTCA
TTTCTTCAGCTATGGATATGTGGCTGATGTTGGGGAGACGGACCTCAGTGTGTTTTATATTGTCTGGTGTTAAGATGATAAATTACTTTG
TGATTACAAGCAAATTTTCTATTTGACAAAGCCCTTGGTGGAGTCCAAATGATTTTTCTGTACCATATTGTTCTCTTACACATACGTATG
TTAGGAAAATAGGCACACTTTCAAAGAGAATGTTCTCTTACACATACGTATGTTAGGAAAATAGACACATTTTCAAAGAGAATGTTCTCT
TACATATGTTAGGAAAATAGGCACACTTTCAAAGAGAGGTATAGGGGCTTTTTACTGCCTTCGAAATCACTTTTAATAAAAGTTGTATGA
TAAATCATTAAAAATGCGAGTGTAAATATTTTTTTTTACCTCTATCAGGGTTTTTATTTGAAAGTGTGCTCTTACCATTTCCTTGTTTGA
GTAAGAGAGTGAATGGTTCTGAGTGTTTAGGAAGGATTTGCTTGCTTGCAGCAGAAGTTCTAGGAAAAGCAGGCACCTCCCAAATATCTT
GAGGACACTGGCAGCCTTATGGTGACTAAATCCACACTTTCTTTAAAGAGATGCAGATGAATTACTTTTCTGTTAATATATAGAAAAATA
CACAGGAGAACATGCAGATACATGTAAATATCTACATACAGGGATATTTGTATGTGTGGTTGTGAAACCCATACACAAGTGGATTTGGCC
ATCTTTGGGCAGTGAGGTCAAATGTGAATATGTGTAAAAGTGCTTTTCAGAACTGCATTACTATGAGAAAACATCAAAACTGCTGTAGTT
TTCCATTTCTACTGTATTTCAGTTGCAACCTATTTTTAATAAACTTTGTATGTATTTAAGTGTATTTGCTATTGTTTTGAAAGTGCTGAC

>79232_79232_6_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000400822_length(amino acids)=1318AA_BP=509
MLLGRANSPPYNSVVRTLPPATLLLRRAGWESFWSCQSRSPWPPRPEVRAPAKGPRGVAGAAGACSAGARLGDAAGGDPASGQAARGCGA
RAPRGLGRTARARDTAMEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNIDDLAQQYADYYNTCF
SDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSAVSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKG
IMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSSNCNSREQSDDETEE
SVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVLDERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTW
GAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQ
LLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLP
WAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASK
SQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSK
SVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQR
WYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSS
GDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRL
EAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLL
EPEAPGLCRPPLPRDYEPPSPSPAPGAPPPPPQRNASYLKTQVLSPDSLFTAKFVAYNEEEEEEDCSLAGPNSYPGSTGAAVGAHDACRD

--------------------------------------------------------------
>79232_79232_7_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000447894_length(transcript)=4081nt_BP=1684nt
ATTTTGAAGAGAGGGGTCCCGGGGAGCTCCCTCCAAGATCTAGAGGCTCCGCGGCCACCCCTGCCGGGTCCTGCCAAGACTTGCTAGAAG
GAACGAGTCGCGTGCCTTAGTTAGTTGGTTCCCGTCACAGGAAGAAACGCCTTTGCAGTGGGTTTAATTGCTTCTGGGCCGAGCGAATTC
CCCGCCGTACAACTCAGTGGTGCGGACTTTGCCTCCTGCTACCCTGTTGCTGCGCCGAGCGGGGTGGGAAAGTTTCTGGAGTTGTCAGTC
GCGCAGCCCGTGGCCACCTAGACCCGAGGTGCGGGCGCCTGCGAAGGGCCCCCGCGGGGTGGCCGGGGCCGCCGGGGCATGCAGCGCGGG
GGCGCGGCTCGGTGACGCCGCGGGCGGGGACCCGGCATCCGGGCAGGCTGCGCGCGGGTGCGGGGCGAGGGCGCCGCGGGGACTGGGACG
CACGGCCCGCGCGCGGGACACGGCCATGGAGGACGCGGGAGCAGCTGGCCCGGGGCCGGAGCCTGAGCCCGAGCCCGAGCCGGAGCCCGA
GCCCGCGCCGGAGCCGGAACCGGAGCCCAAGCCGGGTGCTGGCACATCCGAGGCGTTCTCCCGACTCTGGACCGACGTGATGGGTATCCT
GGACGGTTCACTGGGAAACATCGATGACCTGGCGCAGCAGTATGCAGATTATTACAACACCTGTTTCTCCGACGTGTGCGAGAGGATGGA
GGAGCTGCGGAAACGGCGGGTTTCCCAGGACCTGGAAGTGGAGAAACCCGATGCTAGCCCCACGTCACTTCAGCTGCGGTCCCAGATCGA
AGAGTCGCTTGGCTTCTGTAGCGCCGTGTCAACCCCAGAAGTGGAAAGAAAGAACCCTCTTCATAAATCAAACTCAGAAGACAGCTCTGT
AGGAAAAGGAGACTGGAAGAAGAAAAATAAGTATTTCTGGCAGAACTTCCGAAAGAACCAGAAAGGAATAATGAGACAGACTTCAAAAGG
AGAAGACGTTGGTTATGTTGCCAGTGAAATAACGATGAGCGATGAGGAGCGGATTCAGCTAATGATGATGGTCAAAGAAAAGATGATCAC
AATTGAGGAAGCACTTGCTAGGCTCAAGGAATACGAGGCCCAGCACCGGCAGTCGGCTGCCCTGGACCCTGCTGACTGGCCAGATGGTTC
TTACCCAACGTTTGATGGCTCATCAAACTGCAATTCAAGAGAACAATCGGATGATGAGACTGAGGAGTCGGTGAAGTTTAAGAGGTTACA
CAAGCTGGTAAACTCCACTCGCAGAGTCAGAAAGAAACTAATTAGGGTGGAAGAAATGAAAAAACCCAGCACTGAAGGTGGGGAGGAGCA
CGTGTTTGAGAATTCGCCGGTCCTGGATGAACGGTCCGCCCTCTACTCTGGCGTGCACAAGAAGCCCCTTTTCTTTGATGGCTCTCCTGA
GAAACCTCCCGAAGATGACTCAGACTCTCTCACCACGTCTCCATCCTCCAGCAGCCTGGACACCTGGGGGGCTGGCCGGAAGTTGGTCAA
AACCTTCAGCAAAGGAGAGAGCCGGGGCCTGATTAAGCCCCCCAAGAAGATGGGGACATTCTTCTCCTACCCAGAAGAAGAAAAGGCCCA
GAAAGTGTCCCGCTCCCTCACCGAGGGGGAGATGAAGAAGGGTCTCGGGTCCCTAAGCCACGGGGGTGCTGGTCAAGATAAACTAGGAAT
CTATGTGAAGTCGGTTGTGAAAGGAGGTGCTGCAGATGTGGATGGACGTCTAGCTGCAGGTGATCAGCTCCTCAGTGTGGATGGACGAAG
TCTGGTTGGACTCTCTCAGGAAAGGGCGGCAGAACTCATGACAAGAACAAGCTCTGTGGTGACACTGGAAGTAGCAAAGCAGGGTGCCAT
CTACCACGGTCTGGCCACCCTTCTCAATCAGCCATCCCCCATGATGCAGAGAATTTCAGATCGTCGTGGCTCAGGTAAACCCCGACCAAA
GAGTGAAGGCTTTGAGCTCTATAATAATTCAACTCAAAATGGGTCTCCTGAGAGTCCTCAGCTGCCTTGGGCAGAATATAGTGAACCAAA
GAAATTGCCTGGTGATGACAGACTGATGAAAAATAGAGCTGATCACCGTTCCAGCCCCAACGTAGCAAATCAGCCTCCTAGTCCTGGAGG
GAAAAGTGCATATGCCTCTGGAACAACAGCGAAGATAACATCTGTCTCTACTGGAAACCTCTGCACTGAGGAGCAGACGCCTCCGCCTAG
ACCTGAAGCCTACCCCATCCCCACTCAGACGTACACCAGAGAGTATTTTACCTTCCCAGCTTCCAAATCCCAGGATCGGATGGCTCCTCC
TCAGAACCAGTGGCCAAATTATGAGGAAAAGCCACATATGCACACAGATAGTAATCATTCCAGTATTGCAATTCAGCGTGTTACACGTTC
CCAAGAAGAACTTCGAGAAGATAAAGCTTACCAACTTGAGCGGCATCGAATAGAGGCAGCTATGGACCGAAAGTCTGATAGTGATATGTG
GATAAATCAGAGCTCCTCACTGGACTCCAGTACCTCTAGCCAGGAGCATCTGAACCATTCCTCTAAGTCGGTCACCCCTGCTTCCACACT
GACCAAAAGTGGCCCTGGCCGTTGGAAAACACCAGCAGCCATACCGGCCACCCCTGTGGCCGTCTCCCAGCCAATCCGAACAGACCTGCC
TCCGCCACCCCCGCCACCTCCAGTCCACTATGCCGGTGATTTCGATGGAATGTCCATGGATTTGCCTCTCCCACCACCCCCTTCCGCCAA
CCAGATAGGGCTGCCGTCTGCGCAGGTGGCTGCTGCTGAACGGAGAAAGAGAGAAGAACATCAGCGTTGGTATGAGAAGGAGAAGGCCCG
CCTGGAGGAGGAGCGGGAGAGGAAGCGGAGAGAGCAGGAGAGGAAGTTGGGCCAGATGCGCACTCAGTCCTTAAACCCTGCTCCGTTTTC
TCCCCTGACTGCACAGCAGATGAAGCCCGAAAAGCCTTCCACACTCCAGCGGCCACAGGAAACAGTCATTCGGGAGCTGCAGCCTCAGCA
GCAGCCCCGCACGATCGAGCGCAGAGACTTGCAGTACATTACAGTCAGCAAAGAGGAGCTTTCCTCGGGGGACAGTCTGTCCCCCGACCC
GTGGAAGCGGGACGCCAAGGAGAAGCTGGAGAAGCAGCAGCAGATGCACATCGTGGACATGCTGAGCAAGGAGATCCAGGAGCTCCAGAG
CAAACCGGACCGCAGCGCCGAGGAGAGCGACCGGCTGCGCAAGCTCATGCTGGAGTGGCAGTTCCAGAAGAGACTCCAGGAGTCGAAGCA
GAAGGACGAAGATGACGAGGAGGAGGAGGACGATGATGTGGACACCATGCTGATCATGCAGCGCCTGGAGGCTGAACGAAGAGCGAGGTT
GCAGGACGAGGAGCGGAGGCGGCAGCAGCAGTTAGAAGAGATGCGCAAGCGGGAAGCGGAAGACCGAGCGAGGCAAGAGGAAGAGCGCCG
GCGGCAGGAGGAGGAGCGAACAAAACGAGACGCTGAAGAAAAGAGGCGACAGGAAGAAGGGTATTACAGCCGCCTGGAAGCCGAGAGGCG
CAGACAGCACGACGAGGCGGCGCGCAGGTTGCTGGAGCCCGAGGCGCCCGGTCTGTGCCGCCCTCCGCTTCCCCGGGACTACGAGCCCCC
GTCCCCGTCCCCCGCGCCCGGCGCCCCTCCTCCCCCGCCTCAGCGAAACGCCTCCTACCTCAAAACACAGGTCCTCTCCCCCGACTCGCT
GTTCACTGCCAAGTTTGTTGCATACAATGAGGAGGAGGAGGAGGAGGACTGCAGCCTAGCAGGACCAAACTCTTACCCAGGATCTACTGG
AGCAGCTGTTGGAGCCCATGACGCCTGTCGGGATGCAAAAGAGAAGCGCTCTAAAAGCCAAGATGCAGATTCACCTGGAAGTTCTGGGGC
CCCTGAAAACTTGACATTCAAGGAACGCCAGCGTCTTTTTTCACAAGGTCAAGATGTATCCAATAAAGTGAAAGCTTCTCGTAAATTAAC

>79232_79232_7_SASH1-MLLT4_SASH1_chr6_148841029_ENST00000367467_MLLT4_chr6_168343809_ENST00000447894_length(amino acids)=1308AA_BP=509
MLLGRANSPPYNSVVRTLPPATLLLRRAGWESFWSCQSRSPWPPRPEVRAPAKGPRGVAGAAGACSAGARLGDAAGGDPASGQAARGCGA
RAPRGLGRTARARDTAMEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNIDDLAQQYADYYNTCF
SDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSAVSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKG
IMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSSNCNSREQSDDETEE
SVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVLDERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTW
GAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQ
LLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLP
WAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASK
SQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSK
SVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQR
WYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSS
GDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRL
EAERRARLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGLCRPP
LPRDYEPPSPSPAPGAPPPPPQRNASYLKTQVLSPDSLFTAKFVAYNEEEEEEDCSLAGPNSYPGSTGAAVGAHDACRDAKEKRSKSQDA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SASH1-MLLT4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SASH1-MLLT4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SASH1-MLLT4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource