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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SBF1-MLC1 (FusionGDB2 ID:79286)

Fusion Gene Summary for SBF1-MLC1

Fusion gene summary

Fusion gene information	Fusion gene name: SBF1-MLC1
	Fusion gene ID: 79286
		Hgene	Tgene
	Gene symbol	SBF1	MLC1
	Gene ID	6305	23209
	Gene name	SET binding factor 1	modulator of VRAC current 1
	Synonyms	CMT4B3\|DENND7A\|MTMR5	LVM\|MLC\|VL
	Cytomap	22q13.33	22q13.33
	Type of gene	protein-coding	protein-coding
	Description	myotubularin-related protein 5DENN/MADD domain containing 7Ainactive phosphatidylinositol 3-phosphatase 5	membrane protein MLC1megalencephalic leukoencephalopathy with subcortical cysts 1
	Modification date	20200328	20200313
	UniProtAcc	.	Q15049
	Ensembl transtripts involved in fusion gene	ENST00000348911, ENST00000380817, ENST00000390679, ENST00000476293,	ENST00000483836, ENST00000311597, ENST00000395876, ENST00000431262, ENST00000450140, ENST00000535444, ENST00000538737,
Fusion gene scores	* DoF score	8 X 7 X 8=448	3 X 3 X 3=27
	# samples	10	3
	** MAII score	log2(10/448*10)=-2.16349873228288 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: SBF1 [Title/Abstract] AND MLC1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SBF1(50913215)-MLC1(50506984), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	MLC1	GO:0032388	positive regulation of intracellular transport	19931615

Fusion gene breakpoints across SBF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across MLC1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	PAAD	TCGA-HV-A5A6-01A	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
ChimerDB4	PAAD	TCGA-HV-A5A6	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-

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Fusion Gene ORF analysis for SBF1-MLC1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000348911	ENST00000483836	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
5CDS-5UTR	ENST00000380817	ENST00000483836	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
5CDS-5UTR	ENST00000390679	ENST00000483836	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000348911	ENST00000311597	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000348911	ENST00000395876	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000348911	ENST00000431262	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000348911	ENST00000450140	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000348911	ENST00000535444	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000348911	ENST00000538737	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000380817	ENST00000311597	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000380817	ENST00000395876	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000380817	ENST00000431262	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000380817	ENST00000450140	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000380817	ENST00000535444	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000380817	ENST00000538737	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000390679	ENST00000311597	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000390679	ENST00000395876	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000390679	ENST00000431262	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000390679	ENST00000450140	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000390679	ENST00000535444	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
In-frame	ENST00000390679	ENST00000538737	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
intron-3CDS	ENST00000476293	ENST00000311597	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
intron-3CDS	ENST00000476293	ENST00000395876	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
intron-3CDS	ENST00000476293	ENST00000431262	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
intron-3CDS	ENST00000476293	ENST00000450140	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
intron-3CDS	ENST00000476293	ENST00000535444	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
intron-3CDS	ENST00000476293	ENST00000538737	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-
intron-5UTR	ENST00000476293	ENST00000483836	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000380817	SBF1	chr22	50913215	-	ENST00000395876	MLC1	chr22	50506984	-	2794	239	992	1582	196
ENST00000380817	SBF1	chr22	50913215	-	ENST00000311597	MLC1	chr22	50506984	-	2794	239	992	1582	196
ENST00000380817	SBF1	chr22	50913215	-	ENST00000538737	MLC1	chr22	50506984	-	1130	239	26	601	191
ENST00000380817	SBF1	chr22	50913215	-	ENST00000431262	MLC1	chr22	50506984	-	1022	239	26	601	191
ENST00000380817	SBF1	chr22	50913215	-	ENST00000535444	MLC1	chr22	50506984	-	917	239	26	601	191
ENST00000380817	SBF1	chr22	50913215	-	ENST00000450140	MLC1	chr22	50506984	-	731	239	26	601	191
ENST00000348911	SBF1	chr22	50913215	-	ENST00000395876	MLC1	chr22	50506984	-	2712	157	910	1500	196
ENST00000348911	SBF1	chr22	50913215	-	ENST00000311597	MLC1	chr22	50506984	-	2712	157	910	1500	196
ENST00000348911	SBF1	chr22	50913215	-	ENST00000538737	MLC1	chr22	50506984	-	1048	157	28	519	163
ENST00000348911	SBF1	chr22	50913215	-	ENST00000431262	MLC1	chr22	50506984	-	940	157	28	519	163
ENST00000348911	SBF1	chr22	50913215	-	ENST00000535444	MLC1	chr22	50506984	-	835	157	28	519	163
ENST00000348911	SBF1	chr22	50913215	-	ENST00000450140	MLC1	chr22	50506984	-	649	157	28	519	163
ENST00000390679	SBF1	chr22	50913215	-	ENST00000395876	MLC1	chr22	50506984	-	2795	240	993	1583	196
ENST00000390679	SBF1	chr22	50913215	-	ENST00000311597	MLC1	chr22	50506984	-	2795	240	993	1583	196
ENST00000390679	SBF1	chr22	50913215	-	ENST00000538737	MLC1	chr22	50506984	-	1131	240	27	602	191
ENST00000390679	SBF1	chr22	50913215	-	ENST00000431262	MLC1	chr22	50506984	-	1023	240	27	602	191
ENST00000390679	SBF1	chr22	50913215	-	ENST00000535444	MLC1	chr22	50506984	-	918	240	27	602	191
ENST00000390679	SBF1	chr22	50913215	-	ENST00000450140	MLC1	chr22	50506984	-	732	240	27	602	191

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000380817	ENST00000395876	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.4644129	0.53558713
ENST00000380817	ENST00000311597	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.4644129	0.53558713
ENST00000380817	ENST00000538737	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.51174486	0.48825514
ENST00000380817	ENST00000431262	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.45746347	0.54253656
ENST00000380817	ENST00000535444	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.3353436	0.66465634
ENST00000380817	ENST00000450140	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.36397657	0.63602346
ENST00000348911	ENST00000395876	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.44345537	0.5565446
ENST00000348911	ENST00000311597	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.44345537	0.5565446
ENST00000348911	ENST00000538737	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.6284268	0.37157318
ENST00000348911	ENST00000431262	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.61421174	0.3857882
ENST00000348911	ENST00000535444	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.45483288	0.54516715
ENST00000348911	ENST00000450140	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.52496886	0.4750311
ENST00000390679	ENST00000395876	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.45221823	0.54778177
ENST00000390679	ENST00000311597	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.45221823	0.54778177
ENST00000390679	ENST00000538737	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.49607846	0.50392157
ENST00000390679	ENST00000431262	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.43872035	0.5612797
ENST00000390679	ENST00000535444	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.3159259	0.6840741
ENST00000390679	ENST00000450140	SBF1	chr22	50913215	-	MLC1	chr22	50506984	-	0.35642582	0.6435741

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Fusion Genomic Features for SBF1-MLC1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SBF1-MLC1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:50913215/chr22:50506984)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	MLC1 Q15049
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. {ECO:0000269\|PubMed:22328087}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000311597

257_277

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000311597

304_324

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000395876

257_277

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000395876

304_324

257

378.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000380817

1121_1597

1894.0

Domain

Myotubularin phosphatase

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000380817

1762_1866

1894.0

Domain

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000380817

204_337

1894.0

Domain

cDENN

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000380817

339_440

1894.0

Domain

dDENN

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000380817

7_185

1894.0

Domain

uDENN

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000380817

881_969

1894.0

Domain

GRAM

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000390679

1121_1597

1868.0

Domain

Myotubularin phosphatase

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000390679

1762_1866

1868.0

Domain

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000390679

204_337

1868.0

Domain

cDENN

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000390679

339_440

1868.0

Domain

dDENN

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000390679

7_185

1868.0

Domain

uDENN

Hgene

SBF1

chr22:50913215

chr22:50506984

ENST00000390679

881_969

1868.0

Domain

GRAM

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000311597

173_176

257

378.0

Compositional bias

Note=Poly-Lys

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000395876

173_176

257

378.0

Compositional bias

Note=Poly-Lys

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000311597

111_131

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000311597

144_164

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000311597

199_219

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000311597

230_250

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000311597

52_72

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000311597

82_100

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000395876

111_131

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000395876

144_164

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000395876

199_219

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000395876

230_250

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000395876

52_72

257

378.0

Transmembrane

Helical

Tgene

MLC1

chr22:50913215

chr22:50506984

ENST00000395876

82_100

257

378.0

Transmembrane

Helical

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Fusion Gene Sequence for SBF1-MLC1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>79286_79286_1_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000311597_length(transcript)=2712nt_BP=157nt
GTGCGCGGTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCC
GCGTCCCTCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAG
CAGCCTCACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCC
AGCCATAAAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCA
GTGCGTGCGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGC
CAGGAGCCCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGG
GTGGCAGCGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGT
GAGGGCAAACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTG
AGATCAGTCAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCT
CTTGAGAGCCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGA
CTGTGGGTCCCTGCGTCTCCTGCCCACTCTGACCGGGCTTCCTCCCTCCACGCTTAGGGTCTGTCCCGGGTACTCAGTCAGCCCAGTGGG
ATCTTACCCACTTCCCTGCAAGGTGCACCTGCCCCAGGCTCAGGCTGCCCAGCGGCTCTTCCTGGACAGTGAGAGCAGGGCTGGGCGCCT
CTGTCCTGGCCCGGGAGCCGCAGGGGCCCCTCCTCCAGAGCCTGGGCGCAAGCGACACAGGCTGCCGCTGCTCTCCCAGGTGAAATCCAC
ACCAGTCCACGCCGGGTCGCCTGCCCTGTCTCCCTACTTAGACCCAGTCATTCTAGAGGGATCCACCGCCACACTGGCCGGCCCACGTCC
TGGGTGCTGTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCCCACGTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACATGGCCG
CTGCCCACGTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCTGTGACAGGCAGTGTTCTTGGGGGTGGGGCTGCAT
CCAAGGCTTTGTAAACCGGCTGGACCACGTCTCCCTGGCCCCAGTGACCGGGGGAAGCTGAGCCCCTCCCTCCTGTGTTTGCTCCCATTA
CTCAAAATGCAGGACAGATCAGGTCAGAGCCCAGGAATTCTCACAGGTTCACCCAGCGCCCTCTACCTCCTAGCAAGTACTTTGTCTTGA
TCCTCACTGAGAAGGCCCCAGGGCAGCGGTCTTCTCCATCTCCGCTGTTTTGGGGTCTTAGGGTACAGCCCAGGCGGTCACTGCCCACCT
GCCAGGCTGCAGGGACAGTTGGGTGTGAGAATAACACTGGCTTTGGGTAGTGCCATGGCCAGGAGTGGGTTTCCCTGCGTCTCCTCGTCC
CGAGGGCGCCTGGGTCCTCCCAGCTGACGGCAGTAAATCCACAGTGAGTTGGGGCGACTGTGAAACTGGAATGCTGTTACTTTGATAATT
ACTTTCCAGCAGGTGTTTTCCTTCACAATGGTTTTGTTTCTTTCCTTCTGATCTGAGAAGACATGAACGTTTTCTCTTCACCGCCGTGGG
GTGTATTGACTGGTCCCCCATGGGCTGCTGGAAAGGCCCGGAGATGCATCTGTGGCCTGGGGCCATCAAGATCAAAGAACCAGGAGGCCT
GGGAGATGCAGCTGGATGGGGCGGCCTGCAGACCCTGCCAGGGGGTTTGAGGACCCTCCCAGGTTTCCCACTGCGGAACAGGAGTGACTC
TGGCTGCCAAGATACCTTCATGGTGTTCATGACAAGTGGAATCATTATTTTCAACCATTGAAGGGGGATGCAGGCAAGACACCTTCCCAG
CTGCTCCTAGAGGGGACAAGCCAGGCCCTCTCTGCAGTCCTCGGCAGCTCCGGAAGGACACAGTCAGGGGCCGGGCAAACACTTTGGCCA
CAGCCCCAAACAAGCGCCACCGTGGGAGAGGAGAGGCTGCTGTCACTGGTACCGGATGCAGACCCCACCCTGTCTGCAGGCCACCCCCAC
CTCCCTGCAGCTTTGAGGCTGGCGGGGTCTGCTCCTGGGAATGGGGTGGGAGCCACAGGGACGACCCGGGGCGGGCTGATGTCTTCTTGG
GGGCAGACCAGAGAGCTCAAGTTTCAGAGTCAGAATTAGGCACTTGGAGCGTTTTTGCTGGCTTGCACTTTCTTATTTTCTTATTTTAGA
GCGCTTAAAAAATCCGGAAAAATGGGGTTTAAAAGAACTGTCTCTTTCAGTCTACATTTTTGTTTAATACGCTTGAGCAATAAACGCTGA

>79286_79286_1_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000311597_length(amino acids)=196AA_BP=118
MRLLPTLTGLPPSTLRVCPGYSVSPVGSYPLPCKVHLPQAQAAQRLFLDSESRAGRLCPGPGAAGAPPPEPGRKRHRLPLLSQVKSTPVH
AGSPALSPYLDPVILEGSTATLAGPRPGCCHAQLGVPRGRCPRPGHCHAQLGVPHGRCPRPGHCHAQLGVPRGRCCDRQCSWGWGCIQGF

--------------------------------------------------------------
>79286_79286_2_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000395876_length(transcript)=2712nt_BP=157nt
GTGCGCGGTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCC
GCGTCCCTCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAG
CAGCCTCACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCC
AGCCATAAAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCA
GTGCGTGCGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGC
CAGGAGCCCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGG
GTGGCAGCGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGT
GAGGGCAAACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTG
AGATCAGTCAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCT
CTTGAGAGCCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGA
CTGTGGGTCCCTGCGTCTCCTGCCCACTCTGACCGGGCTTCCTCCCTCCACGCTTAGGGTCTGTCCCGGGTACTCAGTCAGCCCAGTGGG
ATCTTACCCACTTCCCTGCAAGGTGCACCTGCCCCAGGCTCAGGCTGCCCAGCGGCTCTTCCTGGACAGTGAGAGCAGGGCTGGGCGCCT
CTGTCCTGGCCCGGGAGCCGCAGGGGCCCCTCCTCCAGAGCCTGGGCGCAAGCGACACAGGCTGCCGCTGCTCTCCCAGGTGAAATCCAC
ACCAGTCCACGCCGGGTCGCCTGCCCTGTCTCCCTACTTAGACCCAGTCATTCTAGAGGGATCCACCGCCACACTGGCCGGCCCACGTCC
TGGGTGCTGTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCCCACGTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACATGGCCG
CTGCCCACGTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCTGTGACAGGCAGTGTTCTTGGGGGTGGGGCTGCAT
CCAAGGCTTTGTAAACCGGCTGGACCACGTCTCCCTGGCCCCAGTGACCGGGGGAAGCTGAGCCCCTCCCTCCTGTGTTTGCTCCCATTA
CTCAAAATGCAGGACAGATCAGGTCAGAGCCCAGGAATTCTCACAGGTTCACCCAGCGCCCTCTACCTCCTAGCAAGTACTTTGTCTTGA
TCCTCACTGAGAAGGCCCCAGGGCAGCGGTCTTCTCCATCTCCGCTGTTTTGGGGTCTTAGGGTACAGCCCAGGCGGTCACTGCCCACCT
GCCAGGCTGCAGGGACAGTTGGGTGTGAGAATAACACTGGCTTTGGGTAGTGCCATGGCCAGGAGTGGGTTTCCCTGCGTCTCCTCGTCC
CGAGGGCGCCTGGGTCCTCCCAGCTGACGGCAGTAAATCCACAGTGAGTTGGGGCGACTGTGAAACTGGAATGCTGTTACTTTGATAATT
ACTTTCCAGCAGGTGTTTTCCTTCACAATGGTTTTGTTTCTTTCCTTCTGATCTGAGAAGACATGAACGTTTTCTCTTCACCGCCGTGGG
GTGTATTGACTGGTCCCCCATGGGCTGCTGGAAAGGCCCGGAGATGCATCTGTGGCCTGGGGCCATCAAGATCAAAGAACCAGGAGGCCT
GGGAGATGCAGCTGGATGGGGCGGCCTGCAGACCCTGCCAGGGGGTTTGAGGACCCTCCCAGGTTTCCCACTGCGGAACAGGAGTGACTC
TGGCTGCCAAGATACCTTCATGGTGTTCATGACAAGTGGAATCATTATTTTCAACCATTGAAGGGGGATGCAGGCAAGACACCTTCCCAG
CTGCTCCTAGAGGGGACAAGCCAGGCCCTCTCTGCAGTCCTCGGCAGCTCCGGAAGGACACAGTCAGGGGCCGGGCAAACACTTTGGCCA
CAGCCCCAAACAAGCGCCACCGTGGGAGAGGAGAGGCTGCTGTCACTGGTACCGGATGCAGACCCCACCCTGTCTGCAGGCCACCCCCAC
CTCCCTGCAGCTTTGAGGCTGGCGGGGTCTGCTCCTGGGAATGGGGTGGGAGCCACAGGGACGACCCGGGGCGGGCTGATGTCTTCTTGG
GGGCAGACCAGAGAGCTCAAGTTTCAGAGTCAGAATTAGGCACTTGGAGCGTTTTTGCTGGCTTGCACTTTCTTATTTTCTTATTTTAGA
GCGCTTAAAAAATCCGGAAAAATGGGGTTTAAAAGAACTGTCTCTTTCAGTCTACATTTTTGTTTAATACGCTTGAGCAATAAACGCTGA

>79286_79286_2_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000395876_length(amino acids)=196AA_BP=118
MRLLPTLTGLPPSTLRVCPGYSVSPVGSYPLPCKVHLPQAQAAQRLFLDSESRAGRLCPGPGAAGAPPPEPGRKRHRLPLLSQVKSTPVH
AGSPALSPYLDPVILEGSTATLAGPRPGCCHAQLGVPRGRCPRPGHCHAQLGVPHGRCPRPGHCHAQLGVPRGRCCDRQCSWGWGCIQGF

--------------------------------------------------------------
>79286_79286_3_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000431262_length(transcript)=940nt_BP=157nt
GTGCGCGGTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCC
GCGTCCCTCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAG
CAGCCTCACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCC
AGCCATAAAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCA
GTGCGTGCGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGC
CAGGAGCCCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGG
GTGGCAGCGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGT
GAGGGCAAACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTG
AGATCAGTCAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCT
CTTGAGAGCCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGA

>79286_79286_3_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000431262_length(amino acids)=163AA_BP=0
MSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPSYDVL

--------------------------------------------------------------
>79286_79286_4_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000450140_length(transcript)=649nt_BP=157nt
GTGCGCGGTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCC
GCGTCCCTCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAG
CAGCCTCACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCC
AGCCATAAAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCA
GTGCGTGCGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGC
CAGGAGCCCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGG
GTGGCAGCGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGT

>79286_79286_4_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000450140_length(amino acids)=163AA_BP=0
MSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPSYDVL

--------------------------------------------------------------
>79286_79286_5_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000535444_length(transcript)=835nt_BP=157nt
GTGCGCGGTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCC
GCGTCCCTCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAG
CAGCCTCACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCC
AGCCATAAAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCA
GTGCGTGCGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGC
CAGGAGCCCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGG
GTGGCAGCGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGT
GAGGGCAAACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTG
AGATCAGTCAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCT

>79286_79286_5_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000535444_length(amino acids)=163AA_BP=0
MSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPSYDVL

--------------------------------------------------------------
>79286_79286_6_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000538737_length(transcript)=1048nt_BP=157nt
GTGCGCGGTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCC
GCGTCCCTCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAG
CAGCCTCACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCC
AGCCATAAAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCA
GTGCGTGCGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGC
CAGGAGCCCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGG
GTGGCAGCGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGT
GAGGGCAAACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTG
AGATCAGTCAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCT
CTTGAGAGCCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGA
CTGTGGGTCCCTGCGTCTCCTGCCCACTCTGACCGGGCTTCCTCCCTCCACGCTTAGGGTCTGTCCCGGGTACTCAGTCAGCCCAGTGGG

>79286_79286_6_SBF1-MLC1_SBF1_chr22_50913215_ENST00000348911_MLC1_chr22_50506984_ENST00000538737_length(amino acids)=163AA_BP=0
MSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPSYDVL

--------------------------------------------------------------
>79286_79286_7_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000311597_length(transcript)=2794nt_BP=239nt
CTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCGG
TCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCCT
CGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTCA
CGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATAA
AACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTGC
GCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGCC
CCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAGC
GCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCAA
ACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTGAGATCAGT
CAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCTCTTGAGAG
CCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGACTGTGGGT
CCCTGCGTCTCCTGCCCACTCTGACCGGGCTTCCTCCCTCCACGCTTAGGGTCTGTCCCGGGTACTCAGTCAGCCCAGTGGGATCTTACC
CACTTCCCTGCAAGGTGCACCTGCCCCAGGCTCAGGCTGCCCAGCGGCTCTTCCTGGACAGTGAGAGCAGGGCTGGGCGCCTCTGTCCTG
GCCCGGGAGCCGCAGGGGCCCCTCCTCCAGAGCCTGGGCGCAAGCGACACAGGCTGCCGCTGCTCTCCCAGGTGAAATCCACACCAGTCC
ACGCCGGGTCGCCTGCCCTGTCTCCCTACTTAGACCCAGTCATTCTAGAGGGATCCACCGCCACACTGGCCGGCCCACGTCCTGGGTGCT
GTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCCCACGTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACATGGCCGCTGCCCAC
GTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCTGTGACAGGCAGTGTTCTTGGGGGTGGGGCTGCATCCAAGGCT
TTGTAAACCGGCTGGACCACGTCTCCCTGGCCCCAGTGACCGGGGGAAGCTGAGCCCCTCCCTCCTGTGTTTGCTCCCATTACTCAAAAT
GCAGGACAGATCAGGTCAGAGCCCAGGAATTCTCACAGGTTCACCCAGCGCCCTCTACCTCCTAGCAAGTACTTTGTCTTGATCCTCACT
GAGAAGGCCCCAGGGCAGCGGTCTTCTCCATCTCCGCTGTTTTGGGGTCTTAGGGTACAGCCCAGGCGGTCACTGCCCACCTGCCAGGCT
GCAGGGACAGTTGGGTGTGAGAATAACACTGGCTTTGGGTAGTGCCATGGCCAGGAGTGGGTTTCCCTGCGTCTCCTCGTCCCGAGGGCG
CCTGGGTCCTCCCAGCTGACGGCAGTAAATCCACAGTGAGTTGGGGCGACTGTGAAACTGGAATGCTGTTACTTTGATAATTACTTTCCA
GCAGGTGTTTTCCTTCACAATGGTTTTGTTTCTTTCCTTCTGATCTGAGAAGACATGAACGTTTTCTCTTCACCGCCGTGGGGTGTATTG
ACTGGTCCCCCATGGGCTGCTGGAAAGGCCCGGAGATGCATCTGTGGCCTGGGGCCATCAAGATCAAAGAACCAGGAGGCCTGGGAGATG
CAGCTGGATGGGGCGGCCTGCAGACCCTGCCAGGGGGTTTGAGGACCCTCCCAGGTTTCCCACTGCGGAACAGGAGTGACTCTGGCTGCC
AAGATACCTTCATGGTGTTCATGACAAGTGGAATCATTATTTTCAACCATTGAAGGGGGATGCAGGCAAGACACCTTCCCAGCTGCTCCT
AGAGGGGACAAGCCAGGCCCTCTCTGCAGTCCTCGGCAGCTCCGGAAGGACACAGTCAGGGGCCGGGCAAACACTTTGGCCACAGCCCCA
AACAAGCGCCACCGTGGGAGAGGAGAGGCTGCTGTCACTGGTACCGGATGCAGACCCCACCCTGTCTGCAGGCCACCCCCACCTCCCTGC
AGCTTTGAGGCTGGCGGGGTCTGCTCCTGGGAATGGGGTGGGAGCCACAGGGACGACCCGGGGCGGGCTGATGTCTTCTTGGGGGCAGAC
CAGAGAGCTCAAGTTTCAGAGTCAGAATTAGGCACTTGGAGCGTTTTTGCTGGCTTGCACTTTCTTATTTTCTTATTTTAGAGCGCTTAA
AAAATCCGGAAAAATGGGGTTTAAAAGAACTGTCTCTTTCAGTCTACATTTTTGTTTAATACGCTTGAGCAATAAACGCTGACTTGCAGA

>79286_79286_7_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000311597_length(amino acids)=196AA_BP=118
MRLLPTLTGLPPSTLRVCPGYSVSPVGSYPLPCKVHLPQAQAAQRLFLDSESRAGRLCPGPGAAGAPPPEPGRKRHRLPLLSQVKSTPVH
AGSPALSPYLDPVILEGSTATLAGPRPGCCHAQLGVPRGRCPRPGHCHAQLGVPHGRCPRPGHCHAQLGVPRGRCCDRQCSWGWGCIQGF

--------------------------------------------------------------
>79286_79286_8_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000395876_length(transcript)=2794nt_BP=239nt
CTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCGG
TCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCCT
CGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTCA
CGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATAA
AACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTGC
GCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGCC
CCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAGC
GCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCAA
ACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTGAGATCAGT
CAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCTCTTGAGAG
CCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGACTGTGGGT
CCCTGCGTCTCCTGCCCACTCTGACCGGGCTTCCTCCCTCCACGCTTAGGGTCTGTCCCGGGTACTCAGTCAGCCCAGTGGGATCTTACC
CACTTCCCTGCAAGGTGCACCTGCCCCAGGCTCAGGCTGCCCAGCGGCTCTTCCTGGACAGTGAGAGCAGGGCTGGGCGCCTCTGTCCTG
GCCCGGGAGCCGCAGGGGCCCCTCCTCCAGAGCCTGGGCGCAAGCGACACAGGCTGCCGCTGCTCTCCCAGGTGAAATCCACACCAGTCC
ACGCCGGGTCGCCTGCCCTGTCTCCCTACTTAGACCCAGTCATTCTAGAGGGATCCACCGCCACACTGGCCGGCCCACGTCCTGGGTGCT
GTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCCCACGTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACATGGCCGCTGCCCAC
GTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCTGTGACAGGCAGTGTTCTTGGGGGTGGGGCTGCATCCAAGGCT
TTGTAAACCGGCTGGACCACGTCTCCCTGGCCCCAGTGACCGGGGGAAGCTGAGCCCCTCCCTCCTGTGTTTGCTCCCATTACTCAAAAT
GCAGGACAGATCAGGTCAGAGCCCAGGAATTCTCACAGGTTCACCCAGCGCCCTCTACCTCCTAGCAAGTACTTTGTCTTGATCCTCACT
GAGAAGGCCCCAGGGCAGCGGTCTTCTCCATCTCCGCTGTTTTGGGGTCTTAGGGTACAGCCCAGGCGGTCACTGCCCACCTGCCAGGCT
GCAGGGACAGTTGGGTGTGAGAATAACACTGGCTTTGGGTAGTGCCATGGCCAGGAGTGGGTTTCCCTGCGTCTCCTCGTCCCGAGGGCG
CCTGGGTCCTCCCAGCTGACGGCAGTAAATCCACAGTGAGTTGGGGCGACTGTGAAACTGGAATGCTGTTACTTTGATAATTACTTTCCA
GCAGGTGTTTTCCTTCACAATGGTTTTGTTTCTTTCCTTCTGATCTGAGAAGACATGAACGTTTTCTCTTCACCGCCGTGGGGTGTATTG
ACTGGTCCCCCATGGGCTGCTGGAAAGGCCCGGAGATGCATCTGTGGCCTGGGGCCATCAAGATCAAAGAACCAGGAGGCCTGGGAGATG
CAGCTGGATGGGGCGGCCTGCAGACCCTGCCAGGGGGTTTGAGGACCCTCCCAGGTTTCCCACTGCGGAACAGGAGTGACTCTGGCTGCC
AAGATACCTTCATGGTGTTCATGACAAGTGGAATCATTATTTTCAACCATTGAAGGGGGATGCAGGCAAGACACCTTCCCAGCTGCTCCT
AGAGGGGACAAGCCAGGCCCTCTCTGCAGTCCTCGGCAGCTCCGGAAGGACACAGTCAGGGGCCGGGCAAACACTTTGGCCACAGCCCCA
AACAAGCGCCACCGTGGGAGAGGAGAGGCTGCTGTCACTGGTACCGGATGCAGACCCCACCCTGTCTGCAGGCCACCCCCACCTCCCTGC
AGCTTTGAGGCTGGCGGGGTCTGCTCCTGGGAATGGGGTGGGAGCCACAGGGACGACCCGGGGCGGGCTGATGTCTTCTTGGGGGCAGAC
CAGAGAGCTCAAGTTTCAGAGTCAGAATTAGGCACTTGGAGCGTTTTTGCTGGCTTGCACTTTCTTATTTTCTTATTTTAGAGCGCTTAA
AAAATCCGGAAAAATGGGGTTTAAAAGAACTGTCTCTTTCAGTCTACATTTTTGTTTAATACGCTTGAGCAATAAACGCTGACTTGCAGA

>79286_79286_8_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000395876_length(amino acids)=196AA_BP=118
MRLLPTLTGLPPSTLRVCPGYSVSPVGSYPLPCKVHLPQAQAAQRLFLDSESRAGRLCPGPGAAGAPPPEPGRKRHRLPLLSQVKSTPVH
AGSPALSPYLDPVILEGSTATLAGPRPGCCHAQLGVPRGRCPRPGHCHAQLGVPHGRCPRPGHCHAQLGVPRGRCCDRQCSWGWGCIQGF

--------------------------------------------------------------
>79286_79286_9_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000431262_length(transcript)=1022nt_BP=239nt
CTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCGG
TCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCCT
CGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTCA
CGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATAA
AACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTGC
GCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGCC
CCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAGC
GCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCAA
ACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTGAGATCAGT
CAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCTCTTGAGAG
CCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGACTGTGGGT

>79286_79286_9_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000431262_length(amino acids)=191AA_BP=1
MGRRRRRRRRRGANQGCPGCAVQGRGRAMSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTAS
GYLSFSIMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLKEFDKEK

--------------------------------------------------------------
>79286_79286_10_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000450140_length(transcript)=731nt_BP=239nt
CTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCGG
TCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCCT
CGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTCA
CGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATAA
AACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTGC
GCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGCC
CCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAGC
GCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCAA

>79286_79286_10_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000450140_length(amino acids)=191AA_BP=1
MGRRRRRRRRRGANQGCPGCAVQGRGRAMSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTAS
GYLSFSIMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLKEFDKEK

--------------------------------------------------------------
>79286_79286_11_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000535444_length(transcript)=917nt_BP=239nt
CTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCGG
TCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCCT
CGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTCA
CGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATAA
AACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTGC
GCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGCC
CCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAGC
GCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCAA
ACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTGAGATCAGT
CAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCTCTTGAGAG

>79286_79286_11_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000535444_length(amino acids)=191AA_BP=1
MGRRRRRRRRRGANQGCPGCAVQGRGRAMSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTAS
GYLSFSIMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLKEFDKEK

--------------------------------------------------------------
>79286_79286_12_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000538737_length(transcript)=1130nt_BP=239nt
CTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCGG
TCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCCT
CGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTCA
CGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATAA
AACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTGC
GCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGCC
CCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAGC
GCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCAA
ACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTGAGATCAGT
CAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCTCTTGAGAG
CCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGACTGTGGGT
CCCTGCGTCTCCTGCCCACTCTGACCGGGCTTCCTCCCTCCACGCTTAGGGTCTGTCCCGGGTACTCAGTCAGCCCAGTGGGATCTTACC

>79286_79286_12_SBF1-MLC1_SBF1_chr22_50913215_ENST00000380817_MLC1_chr22_50506984_ENST00000538737_length(amino acids)=191AA_BP=1
MGRRRRRRRRRGANQGCPGCAVQGRGRAMSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTAS
GYLSFSIMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLKEFDKEK

--------------------------------------------------------------
>79286_79286_13_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000311597_length(transcript)=2795nt_BP=240nt
GCTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCG
GTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCC
TCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTC
ACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATA
AAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTG
CGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGC
CCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAG
CGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCA
AACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTGAGATCAG
TCAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCTCTTGAGA
GCCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGACTGTGGG
TCCCTGCGTCTCCTGCCCACTCTGACCGGGCTTCCTCCCTCCACGCTTAGGGTCTGTCCCGGGTACTCAGTCAGCCCAGTGGGATCTTAC
CCACTTCCCTGCAAGGTGCACCTGCCCCAGGCTCAGGCTGCCCAGCGGCTCTTCCTGGACAGTGAGAGCAGGGCTGGGCGCCTCTGTCCT
GGCCCGGGAGCCGCAGGGGCCCCTCCTCCAGAGCCTGGGCGCAAGCGACACAGGCTGCCGCTGCTCTCCCAGGTGAAATCCACACCAGTC
CACGCCGGGTCGCCTGCCCTGTCTCCCTACTTAGACCCAGTCATTCTAGAGGGATCCACCGCCACACTGGCCGGCCCACGTCCTGGGTGC
TGTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCCCACGTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACATGGCCGCTGCCCA
CGTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCTGTGACAGGCAGTGTTCTTGGGGGTGGGGCTGCATCCAAGGC
TTTGTAAACCGGCTGGACCACGTCTCCCTGGCCCCAGTGACCGGGGGAAGCTGAGCCCCTCCCTCCTGTGTTTGCTCCCATTACTCAAAA
TGCAGGACAGATCAGGTCAGAGCCCAGGAATTCTCACAGGTTCACCCAGCGCCCTCTACCTCCTAGCAAGTACTTTGTCTTGATCCTCAC
TGAGAAGGCCCCAGGGCAGCGGTCTTCTCCATCTCCGCTGTTTTGGGGTCTTAGGGTACAGCCCAGGCGGTCACTGCCCACCTGCCAGGC
TGCAGGGACAGTTGGGTGTGAGAATAACACTGGCTTTGGGTAGTGCCATGGCCAGGAGTGGGTTTCCCTGCGTCTCCTCGTCCCGAGGGC
GCCTGGGTCCTCCCAGCTGACGGCAGTAAATCCACAGTGAGTTGGGGCGACTGTGAAACTGGAATGCTGTTACTTTGATAATTACTTTCC
AGCAGGTGTTTTCCTTCACAATGGTTTTGTTTCTTTCCTTCTGATCTGAGAAGACATGAACGTTTTCTCTTCACCGCCGTGGGGTGTATT
GACTGGTCCCCCATGGGCTGCTGGAAAGGCCCGGAGATGCATCTGTGGCCTGGGGCCATCAAGATCAAAGAACCAGGAGGCCTGGGAGAT
GCAGCTGGATGGGGCGGCCTGCAGACCCTGCCAGGGGGTTTGAGGACCCTCCCAGGTTTCCCACTGCGGAACAGGAGTGACTCTGGCTGC
CAAGATACCTTCATGGTGTTCATGACAAGTGGAATCATTATTTTCAACCATTGAAGGGGGATGCAGGCAAGACACCTTCCCAGCTGCTCC
TAGAGGGGACAAGCCAGGCCCTCTCTGCAGTCCTCGGCAGCTCCGGAAGGACACAGTCAGGGGCCGGGCAAACACTTTGGCCACAGCCCC
AAACAAGCGCCACCGTGGGAGAGGAGAGGCTGCTGTCACTGGTACCGGATGCAGACCCCACCCTGTCTGCAGGCCACCCCCACCTCCCTG
CAGCTTTGAGGCTGGCGGGGTCTGCTCCTGGGAATGGGGTGGGAGCCACAGGGACGACCCGGGGCGGGCTGATGTCTTCTTGGGGGCAGA
CCAGAGAGCTCAAGTTTCAGAGTCAGAATTAGGCACTTGGAGCGTTTTTGCTGGCTTGCACTTTCTTATTTTCTTATTTTAGAGCGCTTA
AAAAATCCGGAAAAATGGGGTTTAAAAGAACTGTCTCTTTCAGTCTACATTTTTGTTTAATACGCTTGAGCAATAAACGCTGACTTGCAG

>79286_79286_13_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000311597_length(amino acids)=196AA_BP=118
MRLLPTLTGLPPSTLRVCPGYSVSPVGSYPLPCKVHLPQAQAAQRLFLDSESRAGRLCPGPGAAGAPPPEPGRKRHRLPLLSQVKSTPVH
AGSPALSPYLDPVILEGSTATLAGPRPGCCHAQLGVPRGRCPRPGHCHAQLGVPHGRCPRPGHCHAQLGVPRGRCCDRQCSWGWGCIQGF

--------------------------------------------------------------
>79286_79286_14_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000395876_length(transcript)=2795nt_BP=240nt
GCTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCG
GTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCC
TCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTC
ACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATA
AAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTG
CGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGC
CCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAG
CGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCA
AACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTGAGATCAG
TCAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCTCTTGAGA
GCCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGACTGTGGG
TCCCTGCGTCTCCTGCCCACTCTGACCGGGCTTCCTCCCTCCACGCTTAGGGTCTGTCCCGGGTACTCAGTCAGCCCAGTGGGATCTTAC
CCACTTCCCTGCAAGGTGCACCTGCCCCAGGCTCAGGCTGCCCAGCGGCTCTTCCTGGACAGTGAGAGCAGGGCTGGGCGCCTCTGTCCT
GGCCCGGGAGCCGCAGGGGCCCCTCCTCCAGAGCCTGGGCGCAAGCGACACAGGCTGCCGCTGCTCTCCCAGGTGAAATCCACACCAGTC
CACGCCGGGTCGCCTGCCCTGTCTCCCTACTTAGACCCAGTCATTCTAGAGGGATCCACCGCCACACTGGCCGGCCCACGTCCTGGGTGC
TGTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCCCACGTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACATGGCCGCTGCCCA
CGTCCCGGGCACTGTCATGCCCAGCTTGGAGTGCCACGTGGCCGCTGCTGTGACAGGCAGTGTTCTTGGGGGTGGGGCTGCATCCAAGGC
TTTGTAAACCGGCTGGACCACGTCTCCCTGGCCCCAGTGACCGGGGGAAGCTGAGCCCCTCCCTCCTGTGTTTGCTCCCATTACTCAAAA
TGCAGGACAGATCAGGTCAGAGCCCAGGAATTCTCACAGGTTCACCCAGCGCCCTCTACCTCCTAGCAAGTACTTTGTCTTGATCCTCAC
TGAGAAGGCCCCAGGGCAGCGGTCTTCTCCATCTCCGCTGTTTTGGGGTCTTAGGGTACAGCCCAGGCGGTCACTGCCCACCTGCCAGGC
TGCAGGGACAGTTGGGTGTGAGAATAACACTGGCTTTGGGTAGTGCCATGGCCAGGAGTGGGTTTCCCTGCGTCTCCTCGTCCCGAGGGC
GCCTGGGTCCTCCCAGCTGACGGCAGTAAATCCACAGTGAGTTGGGGCGACTGTGAAACTGGAATGCTGTTACTTTGATAATTACTTTCC
AGCAGGTGTTTTCCTTCACAATGGTTTTGTTTCTTTCCTTCTGATCTGAGAAGACATGAACGTTTTCTCTTCACCGCCGTGGGGTGTATT
GACTGGTCCCCCATGGGCTGCTGGAAAGGCCCGGAGATGCATCTGTGGCCTGGGGCCATCAAGATCAAAGAACCAGGAGGCCTGGGAGAT
GCAGCTGGATGGGGCGGCCTGCAGACCCTGCCAGGGGGTTTGAGGACCCTCCCAGGTTTCCCACTGCGGAACAGGAGTGACTCTGGCTGC
CAAGATACCTTCATGGTGTTCATGACAAGTGGAATCATTATTTTCAACCATTGAAGGGGGATGCAGGCAAGACACCTTCCCAGCTGCTCC
TAGAGGGGACAAGCCAGGCCCTCTCTGCAGTCCTCGGCAGCTCCGGAAGGACACAGTCAGGGGCCGGGCAAACACTTTGGCCACAGCCCC
AAACAAGCGCCACCGTGGGAGAGGAGAGGCTGCTGTCACTGGTACCGGATGCAGACCCCACCCTGTCTGCAGGCCACCCCCACCTCCCTG
CAGCTTTGAGGCTGGCGGGGTCTGCTCCTGGGAATGGGGTGGGAGCCACAGGGACGACCCGGGGCGGGCTGATGTCTTCTTGGGGGCAGA
CCAGAGAGCTCAAGTTTCAGAGTCAGAATTAGGCACTTGGAGCGTTTTTGCTGGCTTGCACTTTCTTATTTTCTTATTTTAGAGCGCTTA
AAAAATCCGGAAAAATGGGGTTTAAAAGAACTGTCTCTTTCAGTCTACATTTTTGTTTAATACGCTTGAGCAATAAACGCTGACTTGCAG

>79286_79286_14_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000395876_length(amino acids)=196AA_BP=118
MRLLPTLTGLPPSTLRVCPGYSVSPVGSYPLPCKVHLPQAQAAQRLFLDSESRAGRLCPGPGAAGAPPPEPGRKRHRLPLLSQVKSTPVH
AGSPALSPYLDPVILEGSTATLAGPRPGCCHAQLGVPRGRCPRPGHCHAQLGVPHGRCPRPGHCHAQLGVPRGRCCDRQCSWGWGCIQGF

--------------------------------------------------------------
>79286_79286_15_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000431262_length(transcript)=1023nt_BP=240nt
GCTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCG
GTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCC
TCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTC
ACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATA
AAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTG
CGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGC
CCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAG
CGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCA
AACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTGAGATCAG
TCAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCTCTTGAGA
GCCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGACTGTGGG

>79286_79286_15_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000431262_length(amino acids)=191AA_BP=1
MGRRRRRRRRRGANQGCPGCAVQGRGRAMSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTAS
GYLSFSIMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLKEFDKEK

--------------------------------------------------------------
>79286_79286_16_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000450140_length(transcript)=732nt_BP=240nt
GCTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCG
GTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCC
TCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTC
ACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATA
AAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTG
CGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGC
CCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAG
CGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCA

>79286_79286_16_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000450140_length(amino acids)=191AA_BP=1
MGRRRRRRRRRGANQGCPGCAVQGRGRAMSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTAS
GYLSFSIMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLKEFDKEK

--------------------------------------------------------------
>79286_79286_17_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000535444_length(transcript)=918nt_BP=240nt
GCTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCG
GTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCC
TCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTC
ACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATA
AAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTG
CGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGC
CCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAG
CGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCA
AACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTGAGATCAG
TCAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCTCTTGAGA

>79286_79286_17_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000535444_length(amino acids)=191AA_BP=1
MGRRRRRRRRRGANQGCPGCAVQGRGRAMSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTAS
GYLSFSIMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLKEFDKEK

--------------------------------------------------------------
>79286_79286_18_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000538737_length(transcript)=1131nt_BP=240nt
GCTGGCTGGGAAGATGGCGGCGGGAACCTGGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCGGAGCGAACCAGGGGTGTCCGGGGTGCGCG
GTCCAGGGCCGGGGCCGGGCCATGAGCGCGCCGTCCTCGAGTCCCCGAGCCGCGGAGCCCGCCCGCGCCCCTCGGGCCGCCCCGCGTCCC
TCGCCATGGCGCGGCTCGCGGACTACTTCGTGCTGGTGGCGTTCGGGCCGCACCCGCGCGGTGGAGGTCCTGATTGCCATAAGCAGCCTC
ACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCATTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATA
AAACCATCCTACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGTG
CGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGC
CCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGACCCCCAGACGCGGAAACCGGGTGGCAG
CGCCCAGCCTGGCCCCAAGCATGGAAACGCACAACCCCTAATCGCCCTGAGCTACTGCTTCTAACACCTCTTTTCCCTTGTGTGAGGGCA
AACCAGGCTGCAGGTGGGGTTTTCACTTCCTAGGGTAGTTTAATTTTAAAATAGGCCAATGTTGGCTAGTCTGTGCCTCAGTGAGATCAG
TCAGCTCCGAGTGGCTCCCGTGTCGTAACAGCAGGAGCATGGCCGCAACTTCCCAGGCCGAGGAAGGGCCCCCGGCTCGGCCTCTTGAGA
GCCCCACCCCTGAACTGGCCCCAGCTCCTCTTCCTGCCTCTCTCATGGCTTGGGCTGGAGTGGGCTCTCTGGACCTGACCAGACTGTGGG
TCCCTGCGTCTCCTGCCCACTCTGACCGGGCTTCCTCCCTCCACGCTTAGGGTCTGTCCCGGGTACTCAGTCAGCCCAGTGGGATCTTAC

>79286_79286_18_SBF1-MLC1_SBF1_chr22_50913215_ENST00000390679_MLC1_chr22_50506984_ENST00000538737_length(amino acids)=191AA_BP=1
MGRRRRRRRRRGANQGCPGCAVQGRGRAMSAPSSSPRAAEPARAPRAAPRPSPWRGSRTTSCWWRSGRTRAVEVLIAISSLTSPLLFTAS
GYLSFSIMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLKEFDKEK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SBF1-MLC1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for SBF1-MLC1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for SBF1-MLC1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source