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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SCARB1-AACS (FusionGDB2 ID:79521)

Fusion Gene Summary for SCARB1-AACS

check button Fusion gene summary
Fusion gene informationFusion gene name: SCARB1-AACS
Fusion gene ID: 79521
HgeneTgene
Gene symbol

SCARB1

AACS

Gene ID

949

65985

Gene namescavenger receptor class B member 1acetoacetyl-CoA synthetase
SynonymsCD36L1|CLA-1|CLA1|HDLQTL6|SR-BI|SRB1ACSF1|SUR-5
Cytomap

12q24.31

12q24.31

Type of geneprotein-codingprotein-coding
Descriptionscavenger receptor class B member 1CD36 and LIMPII analogous 1CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1scavenger receptor class B type IIIacetoacetyl-CoA synthetaseacetoacetate-CoA ligaseacyl-CoA synthetase family member 1homolog of C. elegans supressor of ras 5 (sur-5)protein sur-5 homolog
Modification date2020031320200313
UniProtAcc.

Q86V21

Ensembl transtripts involved in fusion geneENST00000261693, ENST00000339570, 
ENST00000376788, ENST00000415380, 
ENST00000546215, ENST00000535005, 
ENST00000540495, ENST00000541205, 
ENST00000544327, 		ENST00000316543, 
ENST00000398953, ENST00000543665, 
ENST00000545511, ENST00000261686, 
ENST00000316519, 
Fusion gene scores* DoF score11 X 8 X 8=7043 X 3 X 3=27
# samples 143
** MAII scorelog2(14/704*10)=-2.33014860169233
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: SCARB1 [Title/Abstract] AND AACS [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSCARB1(125348140)-AACS(125599022), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSCARB1

GO:0010886

positive regulation of cholesterol storage

9211901

HgeneSCARB1

GO:0015920

lipopolysaccharide transport

12651854

HgeneSCARB1

GO:0032497

detection of lipopolysaccharide

12651854

HgeneSCARB1

GO:0034384

high-density lipoprotein particle clearance

9211901

HgeneSCARB1

GO:0043654

recognition of apoptotic cell

9211901

HgeneSCARB1

GO:0051000

positive regulation of nitric-oxide synthase activity

11792700


check buttonFusion gene breakpoints across SCARB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AACS (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A452SCARB1chr12

125348140

-AACSchr12

125599022

+


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Fusion Gene ORF analysis for SCARB1-AACS

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000261693ENST00000316543SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-5UTRENST00000339570ENST00000316543SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-5UTRENST00000376788ENST00000316543SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-5UTRENST00000415380ENST00000316543SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-5UTRENST00000546215ENST00000316543SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000261693ENST00000398953SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000261693ENST00000543665SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000261693ENST00000545511SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000339570ENST00000398953SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000339570ENST00000543665SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000339570ENST00000545511SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000376788ENST00000398953SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000376788ENST00000543665SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000376788ENST00000545511SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000415380ENST00000398953SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000415380ENST00000543665SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000415380ENST00000545511SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000546215ENST00000398953SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000546215ENST00000543665SCARB1chr12

125348140

-AACSchr12

125599022

+
5CDS-intronENST00000546215ENST00000545511SCARB1chr12

125348140

-AACSchr12

125599022

+
In-frameENST00000261693ENST00000261686SCARB1chr12

125348140

-AACSchr12

125599022

+
In-frameENST00000261693ENST00000316519SCARB1chr12

125348140

-AACSchr12

125599022

+
In-frameENST00000339570ENST00000261686SCARB1chr12

125348140

-AACSchr12

125599022

+
In-frameENST00000339570ENST00000316519SCARB1chr12

125348140

-AACSchr12

125599022

+
In-frameENST00000376788ENST00000261686SCARB1chr12

125348140

-AACSchr12

125599022

+
In-frameENST00000376788ENST00000316519SCARB1chr12

125348140

-AACSchr12

125599022

+
In-frameENST00000415380ENST00000261686SCARB1chr12

125348140

-AACSchr12

125599022

+
In-frameENST00000415380ENST00000316519SCARB1chr12

125348140

-AACSchr12

125599022

+
In-frameENST00000546215ENST00000261686SCARB1chr12

125348140

-AACSchr12

125599022

+
In-frameENST00000546215ENST00000316519SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-3CDSENST00000535005ENST00000261686SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-3CDSENST00000535005ENST00000316519SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-3CDSENST00000540495ENST00000261686SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-3CDSENST00000540495ENST00000316519SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-3CDSENST00000541205ENST00000261686SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-3CDSENST00000541205ENST00000316519SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-3CDSENST00000544327ENST00000261686SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-3CDSENST00000544327ENST00000316519SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-5UTRENST00000535005ENST00000316543SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-5UTRENST00000540495ENST00000316543SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-5UTRENST00000541205ENST00000316543SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-5UTRENST00000544327ENST00000316543SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000535005ENST00000398953SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000535005ENST00000543665SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000535005ENST00000545511SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000540495ENST00000398953SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000540495ENST00000543665SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000540495ENST00000545511SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000541205ENST00000398953SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000541205ENST00000543665SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000541205ENST00000545511SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000544327ENST00000398953SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000544327ENST00000543665SCARB1chr12

125348140

-AACSchr12

125599022

+
intron-intronENST00000544327ENST00000545511SCARB1chr12

125348140

-AACSchr12

125599022

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000339570SCARB1chr12125348140-ENST00000316519AACSchr12125599022+2518323321426464
ENST00000339570SCARB1chr12125348140-ENST00000261686AACSchr12125599022+2310323321207391
ENST00000415380SCARB1chr12125348140-ENST00000316519AACSchr12125599022+2447252241355443
ENST00000415380SCARB1chr12125348140-ENST00000261686AACSchr12125599022+2239252241136370
ENST00000261693SCARB1chr12125348140-ENST00000316519AACSchr12125599022+2448253251356443
ENST00000261693SCARB1chr12125348140-ENST00000261686AACSchr12125599022+2240253251137370
ENST00000376788SCARB1chr12125348140-ENST00000316519AACSchr12125599022+2448253251356443
ENST00000376788SCARB1chr12125348140-ENST00000261686AACSchr12125599022+2240253251137370
ENST00000546215SCARB1chr12125348140-ENST00000316519AACSchr12125599022+2384189121292426
ENST00000546215SCARB1chr12125348140-ENST00000261686AACSchr12125599022+2176189121073353

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000339570ENST00000316519SCARB1chr12125348140-AACSchr12125599022+0.0014711620.99852884
ENST00000339570ENST00000261686SCARB1chr12125348140-AACSchr12125599022+0.0170627180.9829373
ENST00000415380ENST00000316519SCARB1chr12125348140-AACSchr12125599022+0.0014163290.9985837
ENST00000415380ENST00000261686SCARB1chr12125348140-AACSchr12125599022+0.0151052120.9848948
ENST00000261693ENST00000316519SCARB1chr12125348140-AACSchr12125599022+0.0014069670.99859303
ENST00000261693ENST00000261686SCARB1chr12125348140-AACSchr12125599022+0.0150098550.9849902
ENST00000376788ENST00000316519SCARB1chr12125348140-AACSchr12125599022+0.0014069670.99859303
ENST00000376788ENST00000261686SCARB1chr12125348140-AACSchr12125599022+0.0150098550.9849902
ENST00000546215ENST00000316519SCARB1chr12125348140-AACSchr12125599022+0.0013835460.99861646
ENST00000546215ENST00000261686SCARB1chr12125348140-AACSchr12125599022+0.0156581290.9843419

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Fusion Genomic Features for SCARB1-AACS


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SCARB1chr12125348140-AACSchr12125599022+5.10E-081
SCARB1chr12125348140-AACSchr12125599022+5.10E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SCARB1-AACS


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:125348140/chr12:125599022)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AACS

Q86V21

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCARB1chr12:125348140chr12:125599022ENST00000261693-1131_1142734.0Topological domainCytoplasmic
HgeneSCARB1chr12:125348140chr12:125599022ENST00000376788-1111_1142616.3333333333334Topological domainCytoplasmic
HgeneSCARB1chr12:125348140chr12:125599022ENST00000415380-1121_1142553.0Topological domainCytoplasmic
HgeneSCARB1chr12:125348140chr12:125599022ENST00000261693-11312_3242734.0TransmembraneHelical
HgeneSCARB1chr12:125348140chr12:125599022ENST00000376788-11112_3242616.3333333333334TransmembraneHelical
HgeneSCARB1chr12:125348140chr12:125599022ENST00000415380-11212_3242553.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCARB1chr12:125348140chr12:125599022ENST00000261693-11333_44342734.0Topological domainExtracellular
HgeneSCARB1chr12:125348140chr12:125599022ENST00000261693-113465_55242734.0Topological domainCytoplasmic
HgeneSCARB1chr12:125348140chr12:125599022ENST00000376788-11133_44342616.3333333333334Topological domainExtracellular
HgeneSCARB1chr12:125348140chr12:125599022ENST00000376788-111465_55242616.3333333333334Topological domainCytoplasmic
HgeneSCARB1chr12:125348140chr12:125599022ENST00000415380-11233_44342553.0Topological domainExtracellular
HgeneSCARB1chr12:125348140chr12:125599022ENST00000415380-112465_55242553.0Topological domainCytoplasmic
HgeneSCARB1chr12:125348140chr12:125599022ENST00000261693-113444_46442734.0TransmembraneHelical
HgeneSCARB1chr12:125348140chr12:125599022ENST00000376788-111444_46442616.3333333333334TransmembraneHelical
HgeneSCARB1chr12:125348140chr12:125599022ENST00000415380-112444_46442553.0TransmembraneHelical


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Fusion Gene Sequence for SCARB1-AACS


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>79521_79521_1_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000261693_AACS_chr12_125599022_ENST00000261686_length(transcript)=2240nt_BP=253nt
CCCGGATCCACCGTGCCTCTGCGGCCTGCGTGCCCGGAGTCCCCGCCTGTGTCGTCTCTGTCGCCGTCCCCGTCTCCTGCCAGGCGCGGA
GCCCTGCGAGCCGCGGGTGGGCCCCAGGCGCGCAGACATGGGCTGCTCCGCCAAAGCGCGCTGGGCTGCCGGGGCGCTGGGCGTCGCGGG
GCTACTGTGCGCTGTGCTGGGCGCTGTCATGATCGTGATGGTGCCGTCGCTCATCAAGCAGCAGGTCCTTAAGGGCACCCTCATCCAGCA
TCTGAAGGAGCACCTGCTGCACGGCAACATGACCAGCAGTGACATCCTCCTGTGCTACACCACGGTCGGCTGGATGATGTGGAACTGGAT
GGTGTCCCTTCTGGCCACAGGAGCGGCCATGGTCTTGTACGATGGCTCCCCCCTGGTGCCCACGCCCAATGTGCTCTGGGACCTGGTTGA
CAGGATAGGCATCACTGTCCTGGTAACTGGGGCCAAGTGGCTGTCAGTGCTGGAAGAGAAGGCCATGAAGCCGGTGGAAACCCACAGTCT
CCAGATGCTCCACACGATCCTGTCCACTGGCTCCCCACTGAAAGCCCAGAGCTACGAGTATGTCTACAGGTGCATCAAGAGCAGCATCCT
CCTGGGCTCCATCTCAGGAGGCACCGACATCATCTCCTGCTTCATGGGCCACAATTTTTCTCTTCCTGTGTATAAAGGGGAGATTCAGGC
CCGGAACCTGGGCATGGCCGTGGAAGCGTGGAACGAGGAAGGAAAGGCGGTCTGGGGAGAGAGCGGCGAGCTGGTGTGTACTAAGCCGAT
CCCTTGCCAGCCCACACACTTCTGGAACGATGAGAACGGCAACAAGTACAGGAAGGCGTATTTCTCCAAATTCCCAGGTATCTGGGCTCA
TGGCGACTACTGCAGAATCAACCCCAAGACCGGGGGCATCGTCATGCTTGGCCGGAGTGACGGCACCCTCAACCCCAACGGGGTGCGGTT
CGGCAGCTCGGAAATCTATAACATTGTATACGCTCAACGGCAAGAAAGTGGAAGTTGCCGTCAAACAGATCATCGCTGGAAAAGCCGTGG
AGCAAGGAGGTGCTTTCTCGAACCCCGAGACCCTGGATCTGTACCGGGACATCCCTGAGCTGCAGGGCTTCTGAGTCAGACTGGCTGGCG
TGTCACTCAGCCGCACCCGTGTGCACTGTAACTTTTGTGTGCTCAAGAAATTATACAGAAACCTACAGCTGTTGTAAAAGGATGCTCGCA
CCAAGTGTTCTGTAGGCTTGGGGAGGGATCGTTTCTCTGTTTTGTTAAATCTGGTGGGTACCTGGATCTTCCACACGAGTGGGATTCTGG
CCTTCAGAGACCAGGAGGGAGTGTCTGGGCCGCAGGTGTGGCACTGTGGTGAGAGTGTGTGTCTTTGCACACACAGTGCAGCGGGAACGG
TGGGGCTGGCTGGTGCTGAAGACAGACACACTCCTGAGCCAAGGTCTTGTCTTCAACCTCCCCGTCCCGTTGTCCCATTTTGCTCTGTGA
AGGTGCAAATCCCTTTCTTCCCTTCCCATCTCAGGCTCTCCTGTTTTCCCTCAGGGTCCAGTATGCCTTTGAGCTTTAGCTGTTAGAAAG
GAACCCCCGTGACTTGACACAGCTTTCACAGCTGGCTGCTAGGACCGGCGGGCTGGGTGTTCACGTGTGTCTGTGTCATGGATGCAATGC
AGGCCCTGGAGGACTGTGCGTCACCCGTCAACCAGAGCGTGCCTCCGGGCCAGCTTCCCTCCAAGGAATGAGTGGATTTCATACAGGATC
TCTTTATTGCACAGACTGAATGGCTTTACATGTTTCTAATGTGAATTAGGCATGTGAAGCAGTGGGTGTCCACCCGTGTCCCTCATGGGT
GAGCCCTCCAGCTGTGAGCCCAGGCAGTGTGGTCACCGAGTGAGGACCCTCCTCACCAGGAACCGCATCCCTGTGCTGCCTCCACCTGAG
AGTTGCTAGGGGGTTCTTGTCGAGATCATGTCATCAGCACCCCTAAGTCAAGTCACGGGTTTCCATAGCCAGGCAGTTGGTATGTACAAT
TCAGTTCAGCGTATGAACTTGTATCTCTAATCTGATGTCCATTTTTATATTTTTTGAAACTGAGCACAATGAAATCCTTTCTTGAATCAT

>79521_79521_1_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000261693_AACS_chr12_125599022_ENST00000261686_length(amino acids)=370AA_BP=74
MRARSPRLCRLCRRPRLLPGAEPCEPRVGPRRADMGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKGTLIQHLKEHLLHG
NMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILS
TGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGESGELVCTKPIPCQPTHFW
NDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVYAQRQESGSCRQTDHRWKSRGARRCFLEP

--------------------------------------------------------------
>79521_79521_2_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000261693_AACS_chr12_125599022_ENST00000316519_length(transcript)=2448nt_BP=253nt
CCCGGATCCACCGTGCCTCTGCGGCCTGCGTGCCCGGAGTCCCCGCCTGTGTCGTCTCTGTCGCCGTCCCCGTCTCCTGCCAGGCGCGGA
GCCCTGCGAGCCGCGGGTGGGCCCCAGGCGCGCAGACATGGGCTGCTCCGCCAAAGCGCGCTGGGCTGCCGGGGCGCTGGGCGTCGCGGG
GCTACTGTGCGCTGTGCTGGGCGCTGTCATGATCGTGATGGTGCCGTCGCTCATCAAGCAGCAGGTCCTTAAGGGCACCCTCATCCAGCA
TCTGAAGGAGCACCTGCTGCACGGCAACATGACCAGCAGTGACATCCTCCTGTGCTACACCACGGTCGGCTGGATGATGTGGAACTGGAT
GGTGTCCCTTCTGGCCACAGGAGCGGCCATGGTCTTGTACGATGGCTCCCCCCTGGTGCCCACGCCCAATGTGCTCTGGGACCTGGTTGA
CAGGATAGGCATCACTGTCCTGGTAACTGGGGCCAAGTGGCTGTCAGTGCTGGAAGAGAAGGCCATGAAGCCGGTGGAAACCCACAGTCT
CCAGATGCTCCACACGATCCTGTCCACTGGCTCCCCACTGAAAGCCCAGAGCTACGAGTATGTCTACAGGTGCATCAAGAGCAGCATCCT
CCTGGGCTCCATCTCAGGAGGCACCGACATCATCTCCTGCTTCATGGGCCACAATTTTTCTCTTCCTGTGTATAAAGGGGAGATTCAGGC
CCGGAACCTGGGCATGGCCGTGGAAGCGTGGAACGAGGAAGGAAAGGCGGTCTGGGGAGAGAGCGGCGAGCTGGTGTGTACTAAGCCGAT
CCCTTGCCAGCCCACACACTTCTGGAACGATGAGAACGGCAACAAGTACAGGAAGGCGTATTTCTCCAAATTCCCAGGTATCTGGGCTCA
TGGCGACTACTGCAGAATCAACCCCAAGACCGGGGGCATCGTCATGCTTGGCCGGAGTGACGGCACCCTCAACCCCAACGGGGTGCGGTT
CGGCAGCTCGGAAATCTATAACATTGTGGAATCCTTCGAGGAGGTGGAGGACAGCCTGTGTGTCCCCCAGTATAACAAGTACAGGGAGGA
GAGGGTGATCCTCTTCCTGAAGATGGCCTCCGGGCACGCCTTCCAGCCTGACTTGGTTAAGAGGATCCGTGACGCCATCCGCATGGGCTT
GTCTGCGCGACACGTGCCCAGCCTCATCCTGGAAACCAAGGGCATCCCGTATACGCTCAACGGCAAGAAAGTGGAAGTTGCCGTCAAACA
GATCATCGCTGGAAAAGCCGTGGAGCAAGGAGGTGCTTTCTCGAACCCCGAGACCCTGGATCTGTACCGGGACATCCCTGAGCTGCAGGG
CTTCTGAGTCAGACTGGCTGGCGTGTCACTCAGCCGCACCCGTGTGCACTGTAACTTTTGTGTGCTCAAGAAATTATACAGAAACCTACA
GCTGTTGTAAAAGGATGCTCGCACCAAGTGTTCTGTAGGCTTGGGGAGGGATCGTTTCTCTGTTTTGTTAAATCTGGTGGGTACCTGGAT
CTTCCACACGAGTGGGATTCTGGCCTTCAGAGACCAGGAGGGAGTGTCTGGGCCGCAGGTGTGGCACTGTGGTGAGAGTGTGTGTCTTTG
CACACACAGTGCAGCGGGAACGGTGGGGCTGGCTGGTGCTGAAGACAGACACACTCCTGAGCCAAGGTCTTGTCTTCAACCTCCCCGTCC
CGTTGTCCCATTTTGCTCTGTGAAGGTGCAAATCCCTTTCTTCCCTTCCCATCTCAGGCTCTCCTGTTTTCCCTCAGGGTCCAGTATGCC
TTTGAGCTTTAGCTGTTAGAAAGGAACCCCCGTGACTTGACACAGCTTTCACAGCTGGCTGCTAGGACCGGCGGGCTGGGTGTTCACGTG
TGTCTGTGTCATGGATGCAATGCAGGCCCTGGAGGACTGTGCGTCACCCGTCAACCAGAGCGTGCCTCCGGGCCAGCTTCCCTCCAAGGA
ATGAGTGGATTTCATACAGGATCTCTTTATTGCACAGACTGAATGGCTTTACATGTTTCTAATGTGAATTAGGCATGTGAAGCAGTGGGT
GTCCACCCGTGTCCCTCATGGGTGAGCCCTCCAGCTGTGAGCCCAGGCAGTGTGGTCACCGAGTGAGGACCCTCCTCACCAGGAACCGCA
TCCCTGTGCTGCCTCCACCTGAGAGTTGCTAGGGGGTTCTTGTCGAGATCATGTCATCAGCACCCCTAAGTCAAGTCACGGGTTTCCATA
GCCAGGCAGTTGGTATGTACAATTCAGTTCAGCGTATGAACTTGTATCTCTAATCTGATGTCCATTTTTATATTTTTTGAAACTGAGCAC
AATGAAATCCTTTCTTGAATCATTTTCCTTTTGGATTATAAAAATATGGGGGAAAGTGCTATGATGAATTTTATGCAATAAATGTATACA

>79521_79521_2_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000261693_AACS_chr12_125599022_ENST00000316519_length(amino acids)=443AA_BP=74
MRARSPRLCRLCRRPRLLPGAEPCEPRVGPRRADMGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKGTLIQHLKEHLLHG
NMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILS
TGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGESGELVCTKPIPCQPTHFW
NDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKM

--------------------------------------------------------------
>79521_79521_3_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000339570_AACS_chr12_125599022_ENST00000261686_length(transcript)=2310nt_BP=323nt
TCCGGCGGCGCCGGCGATGGGGCATAAAACCACTGGCCACCTGCCGGGCTGCTCCTGCGTGCGCTGCCGTCCCGGATCCACCGTGCCTCT
GCGGCCTGCGTGCCCGGAGTCCCCGCCTGTGTCGTCTCTGTCGCCGTCCCCGTCTCCTGCCAGGCGCGGAGCCCTGCGAGCCGCGGGTGG
GCCCCAGGCGCGCAGACATGGGCTGCTCCGCCAAAGCGCGCTGGGCTGCCGGGGCGCTGGGCGTCGCGGGGCTACTGTGCGCTGTGCTGG
GCGCTGTCATGATCGTGATGGTGCCGTCGCTCATCAAGCAGCAGGTCCTTAAGGGCACCCTCATCCAGCATCTGAAGGAGCACCTGCTGC
ACGGCAACATGACCAGCAGTGACATCCTCCTGTGCTACACCACGGTCGGCTGGATGATGTGGAACTGGATGGTGTCCCTTCTGGCCACAG
GAGCGGCCATGGTCTTGTACGATGGCTCCCCCCTGGTGCCCACGCCCAATGTGCTCTGGGACCTGGTTGACAGGATAGGCATCACTGTCC
TGGTAACTGGGGCCAAGTGGCTGTCAGTGCTGGAAGAGAAGGCCATGAAGCCGGTGGAAACCCACAGTCTCCAGATGCTCCACACGATCC
TGTCCACTGGCTCCCCACTGAAAGCCCAGAGCTACGAGTATGTCTACAGGTGCATCAAGAGCAGCATCCTCCTGGGCTCCATCTCAGGAG
GCACCGACATCATCTCCTGCTTCATGGGCCACAATTTTTCTCTTCCTGTGTATAAAGGGGAGATTCAGGCCCGGAACCTGGGCATGGCCG
TGGAAGCGTGGAACGAGGAAGGAAAGGCGGTCTGGGGAGAGAGCGGCGAGCTGGTGTGTACTAAGCCGATCCCTTGCCAGCCCACACACT
TCTGGAACGATGAGAACGGCAACAAGTACAGGAAGGCGTATTTCTCCAAATTCCCAGGTATCTGGGCTCATGGCGACTACTGCAGAATCA
ACCCCAAGACCGGGGGCATCGTCATGCTTGGCCGGAGTGACGGCACCCTCAACCCCAACGGGGTGCGGTTCGGCAGCTCGGAAATCTATA
ACATTGTATACGCTCAACGGCAAGAAAGTGGAAGTTGCCGTCAAACAGATCATCGCTGGAAAAGCCGTGGAGCAAGGAGGTGCTTTCTCG
AACCCCGAGACCCTGGATCTGTACCGGGACATCCCTGAGCTGCAGGGCTTCTGAGTCAGACTGGCTGGCGTGTCACTCAGCCGCACCCGT
GTGCACTGTAACTTTTGTGTGCTCAAGAAATTATACAGAAACCTACAGCTGTTGTAAAAGGATGCTCGCACCAAGTGTTCTGTAGGCTTG
GGGAGGGATCGTTTCTCTGTTTTGTTAAATCTGGTGGGTACCTGGATCTTCCACACGAGTGGGATTCTGGCCTTCAGAGACCAGGAGGGA
GTGTCTGGGCCGCAGGTGTGGCACTGTGGTGAGAGTGTGTGTCTTTGCACACACAGTGCAGCGGGAACGGTGGGGCTGGCTGGTGCTGAA
GACAGACACACTCCTGAGCCAAGGTCTTGTCTTCAACCTCCCCGTCCCGTTGTCCCATTTTGCTCTGTGAAGGTGCAAATCCCTTTCTTC
CCTTCCCATCTCAGGCTCTCCTGTTTTCCCTCAGGGTCCAGTATGCCTTTGAGCTTTAGCTGTTAGAAAGGAACCCCCGTGACTTGACAC
AGCTTTCACAGCTGGCTGCTAGGACCGGCGGGCTGGGTGTTCACGTGTGTCTGTGTCATGGATGCAATGCAGGCCCTGGAGGACTGTGCG
TCACCCGTCAACCAGAGCGTGCCTCCGGGCCAGCTTCCCTCCAAGGAATGAGTGGATTTCATACAGGATCTCTTTATTGCACAGACTGAA
TGGCTTTACATGTTTCTAATGTGAATTAGGCATGTGAAGCAGTGGGTGTCCACCCGTGTCCCTCATGGGTGAGCCCTCCAGCTGTGAGCC
CAGGCAGTGTGGTCACCGAGTGAGGACCCTCCTCACCAGGAACCGCATCCCTGTGCTGCCTCCACCTGAGAGTTGCTAGGGGGTTCTTGT
CGAGATCATGTCATCAGCACCCCTAAGTCAAGTCACGGGTTTCCATAGCCAGGCAGTTGGTATGTACAATTCAGTTCAGCGTATGAACTT
GTATCTCTAATCTGATGTCCATTTTTATATTTTTTGAAACTGAGCACAATGAAATCCTTTCTTGAATCATTTTCCTTTTGGATTATAAAA

>79521_79521_3_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000339570_AACS_chr12_125599022_ENST00000261686_length(amino acids)=391AA_BP=95
MATCRAAPACAAVPDPPCLCGLRARSPRLCRLCRRPRLLPGAEPCEPRVGPRRADMGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSL
IKQQVLKGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVL
EEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAV
WGESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVYAQRQESG

--------------------------------------------------------------
>79521_79521_4_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000339570_AACS_chr12_125599022_ENST00000316519_length(transcript)=2518nt_BP=323nt
TCCGGCGGCGCCGGCGATGGGGCATAAAACCACTGGCCACCTGCCGGGCTGCTCCTGCGTGCGCTGCCGTCCCGGATCCACCGTGCCTCT
GCGGCCTGCGTGCCCGGAGTCCCCGCCTGTGTCGTCTCTGTCGCCGTCCCCGTCTCCTGCCAGGCGCGGAGCCCTGCGAGCCGCGGGTGG
GCCCCAGGCGCGCAGACATGGGCTGCTCCGCCAAAGCGCGCTGGGCTGCCGGGGCGCTGGGCGTCGCGGGGCTACTGTGCGCTGTGCTGG
GCGCTGTCATGATCGTGATGGTGCCGTCGCTCATCAAGCAGCAGGTCCTTAAGGGCACCCTCATCCAGCATCTGAAGGAGCACCTGCTGC
ACGGCAACATGACCAGCAGTGACATCCTCCTGTGCTACACCACGGTCGGCTGGATGATGTGGAACTGGATGGTGTCCCTTCTGGCCACAG
GAGCGGCCATGGTCTTGTACGATGGCTCCCCCCTGGTGCCCACGCCCAATGTGCTCTGGGACCTGGTTGACAGGATAGGCATCACTGTCC
TGGTAACTGGGGCCAAGTGGCTGTCAGTGCTGGAAGAGAAGGCCATGAAGCCGGTGGAAACCCACAGTCTCCAGATGCTCCACACGATCC
TGTCCACTGGCTCCCCACTGAAAGCCCAGAGCTACGAGTATGTCTACAGGTGCATCAAGAGCAGCATCCTCCTGGGCTCCATCTCAGGAG
GCACCGACATCATCTCCTGCTTCATGGGCCACAATTTTTCTCTTCCTGTGTATAAAGGGGAGATTCAGGCCCGGAACCTGGGCATGGCCG
TGGAAGCGTGGAACGAGGAAGGAAAGGCGGTCTGGGGAGAGAGCGGCGAGCTGGTGTGTACTAAGCCGATCCCTTGCCAGCCCACACACT
TCTGGAACGATGAGAACGGCAACAAGTACAGGAAGGCGTATTTCTCCAAATTCCCAGGTATCTGGGCTCATGGCGACTACTGCAGAATCA
ACCCCAAGACCGGGGGCATCGTCATGCTTGGCCGGAGTGACGGCACCCTCAACCCCAACGGGGTGCGGTTCGGCAGCTCGGAAATCTATA
ACATTGTGGAATCCTTCGAGGAGGTGGAGGACAGCCTGTGTGTCCCCCAGTATAACAAGTACAGGGAGGAGAGGGTGATCCTCTTCCTGA
AGATGGCCTCCGGGCACGCCTTCCAGCCTGACTTGGTTAAGAGGATCCGTGACGCCATCCGCATGGGCTTGTCTGCGCGACACGTGCCCA
GCCTCATCCTGGAAACCAAGGGCATCCCGTATACGCTCAACGGCAAGAAAGTGGAAGTTGCCGTCAAACAGATCATCGCTGGAAAAGCCG
TGGAGCAAGGAGGTGCTTTCTCGAACCCCGAGACCCTGGATCTGTACCGGGACATCCCTGAGCTGCAGGGCTTCTGAGTCAGACTGGCTG
GCGTGTCACTCAGCCGCACCCGTGTGCACTGTAACTTTTGTGTGCTCAAGAAATTATACAGAAACCTACAGCTGTTGTAAAAGGATGCTC
GCACCAAGTGTTCTGTAGGCTTGGGGAGGGATCGTTTCTCTGTTTTGTTAAATCTGGTGGGTACCTGGATCTTCCACACGAGTGGGATTC
TGGCCTTCAGAGACCAGGAGGGAGTGTCTGGGCCGCAGGTGTGGCACTGTGGTGAGAGTGTGTGTCTTTGCACACACAGTGCAGCGGGAA
CGGTGGGGCTGGCTGGTGCTGAAGACAGACACACTCCTGAGCCAAGGTCTTGTCTTCAACCTCCCCGTCCCGTTGTCCCATTTTGCTCTG
TGAAGGTGCAAATCCCTTTCTTCCCTTCCCATCTCAGGCTCTCCTGTTTTCCCTCAGGGTCCAGTATGCCTTTGAGCTTTAGCTGTTAGA
AAGGAACCCCCGTGACTTGACACAGCTTTCACAGCTGGCTGCTAGGACCGGCGGGCTGGGTGTTCACGTGTGTCTGTGTCATGGATGCAA
TGCAGGCCCTGGAGGACTGTGCGTCACCCGTCAACCAGAGCGTGCCTCCGGGCCAGCTTCCCTCCAAGGAATGAGTGGATTTCATACAGG
ATCTCTTTATTGCACAGACTGAATGGCTTTACATGTTTCTAATGTGAATTAGGCATGTGAAGCAGTGGGTGTCCACCCGTGTCCCTCATG
GGTGAGCCCTCCAGCTGTGAGCCCAGGCAGTGTGGTCACCGAGTGAGGACCCTCCTCACCAGGAACCGCATCCCTGTGCTGCCTCCACCT
GAGAGTTGCTAGGGGGTTCTTGTCGAGATCATGTCATCAGCACCCCTAAGTCAAGTCACGGGTTTCCATAGCCAGGCAGTTGGTATGTAC
AATTCAGTTCAGCGTATGAACTTGTATCTCTAATCTGATGTCCATTTTTATATTTTTTGAAACTGAGCACAATGAAATCCTTTCTTGAAT

>79521_79521_4_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000339570_AACS_chr12_125599022_ENST00000316519_length(amino acids)=464AA_BP=95
MATCRAAPACAAVPDPPCLCGLRARSPRLCRLCRRPRLLPGAEPCEPRVGPRRADMGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSL
IKQQVLKGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVL
EEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAV
WGESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFEEVED
SLCVPQYNKYREERVILFLKMASGHAFQPDLVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGKKVEVAVKQIIAGKAVEQGGAFSNPE

--------------------------------------------------------------
>79521_79521_5_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000376788_AACS_chr12_125599022_ENST00000261686_length(transcript)=2240nt_BP=253nt
CCCGGATCCACCGTGCCTCTGCGGCCTGCGTGCCCGGAGTCCCCGCCTGTGTCGTCTCTGTCGCCGTCCCCGTCTCCTGCCAGGCGCGGA
GCCCTGCGAGCCGCGGGTGGGCCCCAGGCGCGCAGACATGGGCTGCTCCGCCAAAGCGCGCTGGGCTGCCGGGGCGCTGGGCGTCGCGGG
GCTACTGTGCGCTGTGCTGGGCGCTGTCATGATCGTGATGGTGCCGTCGCTCATCAAGCAGCAGGTCCTTAAGGGCACCCTCATCCAGCA
TCTGAAGGAGCACCTGCTGCACGGCAACATGACCAGCAGTGACATCCTCCTGTGCTACACCACGGTCGGCTGGATGATGTGGAACTGGAT
GGTGTCCCTTCTGGCCACAGGAGCGGCCATGGTCTTGTACGATGGCTCCCCCCTGGTGCCCACGCCCAATGTGCTCTGGGACCTGGTTGA
CAGGATAGGCATCACTGTCCTGGTAACTGGGGCCAAGTGGCTGTCAGTGCTGGAAGAGAAGGCCATGAAGCCGGTGGAAACCCACAGTCT
CCAGATGCTCCACACGATCCTGTCCACTGGCTCCCCACTGAAAGCCCAGAGCTACGAGTATGTCTACAGGTGCATCAAGAGCAGCATCCT
CCTGGGCTCCATCTCAGGAGGCACCGACATCATCTCCTGCTTCATGGGCCACAATTTTTCTCTTCCTGTGTATAAAGGGGAGATTCAGGC
CCGGAACCTGGGCATGGCCGTGGAAGCGTGGAACGAGGAAGGAAAGGCGGTCTGGGGAGAGAGCGGCGAGCTGGTGTGTACTAAGCCGAT
CCCTTGCCAGCCCACACACTTCTGGAACGATGAGAACGGCAACAAGTACAGGAAGGCGTATTTCTCCAAATTCCCAGGTATCTGGGCTCA
TGGCGACTACTGCAGAATCAACCCCAAGACCGGGGGCATCGTCATGCTTGGCCGGAGTGACGGCACCCTCAACCCCAACGGGGTGCGGTT
CGGCAGCTCGGAAATCTATAACATTGTATACGCTCAACGGCAAGAAAGTGGAAGTTGCCGTCAAACAGATCATCGCTGGAAAAGCCGTGG
AGCAAGGAGGTGCTTTCTCGAACCCCGAGACCCTGGATCTGTACCGGGACATCCCTGAGCTGCAGGGCTTCTGAGTCAGACTGGCTGGCG
TGTCACTCAGCCGCACCCGTGTGCACTGTAACTTTTGTGTGCTCAAGAAATTATACAGAAACCTACAGCTGTTGTAAAAGGATGCTCGCA
CCAAGTGTTCTGTAGGCTTGGGGAGGGATCGTTTCTCTGTTTTGTTAAATCTGGTGGGTACCTGGATCTTCCACACGAGTGGGATTCTGG
CCTTCAGAGACCAGGAGGGAGTGTCTGGGCCGCAGGTGTGGCACTGTGGTGAGAGTGTGTGTCTTTGCACACACAGTGCAGCGGGAACGG
TGGGGCTGGCTGGTGCTGAAGACAGACACACTCCTGAGCCAAGGTCTTGTCTTCAACCTCCCCGTCCCGTTGTCCCATTTTGCTCTGTGA
AGGTGCAAATCCCTTTCTTCCCTTCCCATCTCAGGCTCTCCTGTTTTCCCTCAGGGTCCAGTATGCCTTTGAGCTTTAGCTGTTAGAAAG
GAACCCCCGTGACTTGACACAGCTTTCACAGCTGGCTGCTAGGACCGGCGGGCTGGGTGTTCACGTGTGTCTGTGTCATGGATGCAATGC
AGGCCCTGGAGGACTGTGCGTCACCCGTCAACCAGAGCGTGCCTCCGGGCCAGCTTCCCTCCAAGGAATGAGTGGATTTCATACAGGATC
TCTTTATTGCACAGACTGAATGGCTTTACATGTTTCTAATGTGAATTAGGCATGTGAAGCAGTGGGTGTCCACCCGTGTCCCTCATGGGT
GAGCCCTCCAGCTGTGAGCCCAGGCAGTGTGGTCACCGAGTGAGGACCCTCCTCACCAGGAACCGCATCCCTGTGCTGCCTCCACCTGAG
AGTTGCTAGGGGGTTCTTGTCGAGATCATGTCATCAGCACCCCTAAGTCAAGTCACGGGTTTCCATAGCCAGGCAGTTGGTATGTACAAT
TCAGTTCAGCGTATGAACTTGTATCTCTAATCTGATGTCCATTTTTATATTTTTTGAAACTGAGCACAATGAAATCCTTTCTTGAATCAT

>79521_79521_5_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000376788_AACS_chr12_125599022_ENST00000261686_length(amino acids)=370AA_BP=74
MRARSPRLCRLCRRPRLLPGAEPCEPRVGPRRADMGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKGTLIQHLKEHLLHG
NMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILS
TGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGESGELVCTKPIPCQPTHFW
NDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVYAQRQESGSCRQTDHRWKSRGARRCFLEP

--------------------------------------------------------------
>79521_79521_6_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000376788_AACS_chr12_125599022_ENST00000316519_length(transcript)=2448nt_BP=253nt
CCCGGATCCACCGTGCCTCTGCGGCCTGCGTGCCCGGAGTCCCCGCCTGTGTCGTCTCTGTCGCCGTCCCCGTCTCCTGCCAGGCGCGGA
GCCCTGCGAGCCGCGGGTGGGCCCCAGGCGCGCAGACATGGGCTGCTCCGCCAAAGCGCGCTGGGCTGCCGGGGCGCTGGGCGTCGCGGG
GCTACTGTGCGCTGTGCTGGGCGCTGTCATGATCGTGATGGTGCCGTCGCTCATCAAGCAGCAGGTCCTTAAGGGCACCCTCATCCAGCA
TCTGAAGGAGCACCTGCTGCACGGCAACATGACCAGCAGTGACATCCTCCTGTGCTACACCACGGTCGGCTGGATGATGTGGAACTGGAT
GGTGTCCCTTCTGGCCACAGGAGCGGCCATGGTCTTGTACGATGGCTCCCCCCTGGTGCCCACGCCCAATGTGCTCTGGGACCTGGTTGA
CAGGATAGGCATCACTGTCCTGGTAACTGGGGCCAAGTGGCTGTCAGTGCTGGAAGAGAAGGCCATGAAGCCGGTGGAAACCCACAGTCT
CCAGATGCTCCACACGATCCTGTCCACTGGCTCCCCACTGAAAGCCCAGAGCTACGAGTATGTCTACAGGTGCATCAAGAGCAGCATCCT
CCTGGGCTCCATCTCAGGAGGCACCGACATCATCTCCTGCTTCATGGGCCACAATTTTTCTCTTCCTGTGTATAAAGGGGAGATTCAGGC
CCGGAACCTGGGCATGGCCGTGGAAGCGTGGAACGAGGAAGGAAAGGCGGTCTGGGGAGAGAGCGGCGAGCTGGTGTGTACTAAGCCGAT
CCCTTGCCAGCCCACACACTTCTGGAACGATGAGAACGGCAACAAGTACAGGAAGGCGTATTTCTCCAAATTCCCAGGTATCTGGGCTCA
TGGCGACTACTGCAGAATCAACCCCAAGACCGGGGGCATCGTCATGCTTGGCCGGAGTGACGGCACCCTCAACCCCAACGGGGTGCGGTT
CGGCAGCTCGGAAATCTATAACATTGTGGAATCCTTCGAGGAGGTGGAGGACAGCCTGTGTGTCCCCCAGTATAACAAGTACAGGGAGGA
GAGGGTGATCCTCTTCCTGAAGATGGCCTCCGGGCACGCCTTCCAGCCTGACTTGGTTAAGAGGATCCGTGACGCCATCCGCATGGGCTT
GTCTGCGCGACACGTGCCCAGCCTCATCCTGGAAACCAAGGGCATCCCGTATACGCTCAACGGCAAGAAAGTGGAAGTTGCCGTCAAACA
GATCATCGCTGGAAAAGCCGTGGAGCAAGGAGGTGCTTTCTCGAACCCCGAGACCCTGGATCTGTACCGGGACATCCCTGAGCTGCAGGG
CTTCTGAGTCAGACTGGCTGGCGTGTCACTCAGCCGCACCCGTGTGCACTGTAACTTTTGTGTGCTCAAGAAATTATACAGAAACCTACA
GCTGTTGTAAAAGGATGCTCGCACCAAGTGTTCTGTAGGCTTGGGGAGGGATCGTTTCTCTGTTTTGTTAAATCTGGTGGGTACCTGGAT
CTTCCACACGAGTGGGATTCTGGCCTTCAGAGACCAGGAGGGAGTGTCTGGGCCGCAGGTGTGGCACTGTGGTGAGAGTGTGTGTCTTTG
CACACACAGTGCAGCGGGAACGGTGGGGCTGGCTGGTGCTGAAGACAGACACACTCCTGAGCCAAGGTCTTGTCTTCAACCTCCCCGTCC
CGTTGTCCCATTTTGCTCTGTGAAGGTGCAAATCCCTTTCTTCCCTTCCCATCTCAGGCTCTCCTGTTTTCCCTCAGGGTCCAGTATGCC
TTTGAGCTTTAGCTGTTAGAAAGGAACCCCCGTGACTTGACACAGCTTTCACAGCTGGCTGCTAGGACCGGCGGGCTGGGTGTTCACGTG
TGTCTGTGTCATGGATGCAATGCAGGCCCTGGAGGACTGTGCGTCACCCGTCAACCAGAGCGTGCCTCCGGGCCAGCTTCCCTCCAAGGA
ATGAGTGGATTTCATACAGGATCTCTTTATTGCACAGACTGAATGGCTTTACATGTTTCTAATGTGAATTAGGCATGTGAAGCAGTGGGT
GTCCACCCGTGTCCCTCATGGGTGAGCCCTCCAGCTGTGAGCCCAGGCAGTGTGGTCACCGAGTGAGGACCCTCCTCACCAGGAACCGCA
TCCCTGTGCTGCCTCCACCTGAGAGTTGCTAGGGGGTTCTTGTCGAGATCATGTCATCAGCACCCCTAAGTCAAGTCACGGGTTTCCATA
GCCAGGCAGTTGGTATGTACAATTCAGTTCAGCGTATGAACTTGTATCTCTAATCTGATGTCCATTTTTATATTTTTTGAAACTGAGCAC
AATGAAATCCTTTCTTGAATCATTTTCCTTTTGGATTATAAAAATATGGGGGAAAGTGCTATGATGAATTTTATGCAATAAATGTATACA

>79521_79521_6_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000376788_AACS_chr12_125599022_ENST00000316519_length(amino acids)=443AA_BP=74
MRARSPRLCRLCRRPRLLPGAEPCEPRVGPRRADMGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKGTLIQHLKEHLLHG
NMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILS
TGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGESGELVCTKPIPCQPTHFW
NDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKM

--------------------------------------------------------------
>79521_79521_7_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000415380_AACS_chr12_125599022_ENST00000261686_length(transcript)=2239nt_BP=252nt
CCGGATCCACCGTGCCTCTGCGGCCTGCGTGCCCGGAGTCCCCGCCTGTGTCGTCTCTGTCGCCGTCCCCGTCTCCTGCCAGGCGCGGAG
CCCTGCGAGCCGCGGGTGGGCCCCAGGCGCGCAGACATGGGCTGCTCCGCCAAAGCGCGCTGGGCTGCCGGGGCGCTGGGCGTCGCGGGG
CTACTGTGCGCTGTGCTGGGCGCTGTCATGATCGTGATGGTGCCGTCGCTCATCAAGCAGCAGGTCCTTAAGGGCACCCTCATCCAGCAT
CTGAAGGAGCACCTGCTGCACGGCAACATGACCAGCAGTGACATCCTCCTGTGCTACACCACGGTCGGCTGGATGATGTGGAACTGGATG
GTGTCCCTTCTGGCCACAGGAGCGGCCATGGTCTTGTACGATGGCTCCCCCCTGGTGCCCACGCCCAATGTGCTCTGGGACCTGGTTGAC
AGGATAGGCATCACTGTCCTGGTAACTGGGGCCAAGTGGCTGTCAGTGCTGGAAGAGAAGGCCATGAAGCCGGTGGAAACCCACAGTCTC
CAGATGCTCCACACGATCCTGTCCACTGGCTCCCCACTGAAAGCCCAGAGCTACGAGTATGTCTACAGGTGCATCAAGAGCAGCATCCTC
CTGGGCTCCATCTCAGGAGGCACCGACATCATCTCCTGCTTCATGGGCCACAATTTTTCTCTTCCTGTGTATAAAGGGGAGATTCAGGCC
CGGAACCTGGGCATGGCCGTGGAAGCGTGGAACGAGGAAGGAAAGGCGGTCTGGGGAGAGAGCGGCGAGCTGGTGTGTACTAAGCCGATC
CCTTGCCAGCCCACACACTTCTGGAACGATGAGAACGGCAACAAGTACAGGAAGGCGTATTTCTCCAAATTCCCAGGTATCTGGGCTCAT
GGCGACTACTGCAGAATCAACCCCAAGACCGGGGGCATCGTCATGCTTGGCCGGAGTGACGGCACCCTCAACCCCAACGGGGTGCGGTTC
GGCAGCTCGGAAATCTATAACATTGTATACGCTCAACGGCAAGAAAGTGGAAGTTGCCGTCAAACAGATCATCGCTGGAAAAGCCGTGGA
GCAAGGAGGTGCTTTCTCGAACCCCGAGACCCTGGATCTGTACCGGGACATCCCTGAGCTGCAGGGCTTCTGAGTCAGACTGGCTGGCGT
GTCACTCAGCCGCACCCGTGTGCACTGTAACTTTTGTGTGCTCAAGAAATTATACAGAAACCTACAGCTGTTGTAAAAGGATGCTCGCAC
CAAGTGTTCTGTAGGCTTGGGGAGGGATCGTTTCTCTGTTTTGTTAAATCTGGTGGGTACCTGGATCTTCCACACGAGTGGGATTCTGGC
CTTCAGAGACCAGGAGGGAGTGTCTGGGCCGCAGGTGTGGCACTGTGGTGAGAGTGTGTGTCTTTGCACACACAGTGCAGCGGGAACGGT
GGGGCTGGCTGGTGCTGAAGACAGACACACTCCTGAGCCAAGGTCTTGTCTTCAACCTCCCCGTCCCGTTGTCCCATTTTGCTCTGTGAA
GGTGCAAATCCCTTTCTTCCCTTCCCATCTCAGGCTCTCCTGTTTTCCCTCAGGGTCCAGTATGCCTTTGAGCTTTAGCTGTTAGAAAGG
AACCCCCGTGACTTGACACAGCTTTCACAGCTGGCTGCTAGGACCGGCGGGCTGGGTGTTCACGTGTGTCTGTGTCATGGATGCAATGCA
GGCCCTGGAGGACTGTGCGTCACCCGTCAACCAGAGCGTGCCTCCGGGCCAGCTTCCCTCCAAGGAATGAGTGGATTTCATACAGGATCT
CTTTATTGCACAGACTGAATGGCTTTACATGTTTCTAATGTGAATTAGGCATGTGAAGCAGTGGGTGTCCACCCGTGTCCCTCATGGGTG
AGCCCTCCAGCTGTGAGCCCAGGCAGTGTGGTCACCGAGTGAGGACCCTCCTCACCAGGAACCGCATCCCTGTGCTGCCTCCACCTGAGA
GTTGCTAGGGGGTTCTTGTCGAGATCATGTCATCAGCACCCCTAAGTCAAGTCACGGGTTTCCATAGCCAGGCAGTTGGTATGTACAATT
CAGTTCAGCGTATGAACTTGTATCTCTAATCTGATGTCCATTTTTATATTTTTTGAAACTGAGCACAATGAAATCCTTTCTTGAATCATT

>79521_79521_7_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000415380_AACS_chr12_125599022_ENST00000261686_length(amino acids)=370AA_BP=74
MRARSPRLCRLCRRPRLLPGAEPCEPRVGPRRADMGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKGTLIQHLKEHLLHG
NMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILS
TGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGESGELVCTKPIPCQPTHFW
NDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVYAQRQESGSCRQTDHRWKSRGARRCFLEP

--------------------------------------------------------------
>79521_79521_8_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000415380_AACS_chr12_125599022_ENST00000316519_length(transcript)=2447nt_BP=252nt
CCGGATCCACCGTGCCTCTGCGGCCTGCGTGCCCGGAGTCCCCGCCTGTGTCGTCTCTGTCGCCGTCCCCGTCTCCTGCCAGGCGCGGAG
CCCTGCGAGCCGCGGGTGGGCCCCAGGCGCGCAGACATGGGCTGCTCCGCCAAAGCGCGCTGGGCTGCCGGGGCGCTGGGCGTCGCGGGG
CTACTGTGCGCTGTGCTGGGCGCTGTCATGATCGTGATGGTGCCGTCGCTCATCAAGCAGCAGGTCCTTAAGGGCACCCTCATCCAGCAT
CTGAAGGAGCACCTGCTGCACGGCAACATGACCAGCAGTGACATCCTCCTGTGCTACACCACGGTCGGCTGGATGATGTGGAACTGGATG
GTGTCCCTTCTGGCCACAGGAGCGGCCATGGTCTTGTACGATGGCTCCCCCCTGGTGCCCACGCCCAATGTGCTCTGGGACCTGGTTGAC
AGGATAGGCATCACTGTCCTGGTAACTGGGGCCAAGTGGCTGTCAGTGCTGGAAGAGAAGGCCATGAAGCCGGTGGAAACCCACAGTCTC
CAGATGCTCCACACGATCCTGTCCACTGGCTCCCCACTGAAAGCCCAGAGCTACGAGTATGTCTACAGGTGCATCAAGAGCAGCATCCTC
CTGGGCTCCATCTCAGGAGGCACCGACATCATCTCCTGCTTCATGGGCCACAATTTTTCTCTTCCTGTGTATAAAGGGGAGATTCAGGCC
CGGAACCTGGGCATGGCCGTGGAAGCGTGGAACGAGGAAGGAAAGGCGGTCTGGGGAGAGAGCGGCGAGCTGGTGTGTACTAAGCCGATC
CCTTGCCAGCCCACACACTTCTGGAACGATGAGAACGGCAACAAGTACAGGAAGGCGTATTTCTCCAAATTCCCAGGTATCTGGGCTCAT
GGCGACTACTGCAGAATCAACCCCAAGACCGGGGGCATCGTCATGCTTGGCCGGAGTGACGGCACCCTCAACCCCAACGGGGTGCGGTTC
GGCAGCTCGGAAATCTATAACATTGTGGAATCCTTCGAGGAGGTGGAGGACAGCCTGTGTGTCCCCCAGTATAACAAGTACAGGGAGGAG
AGGGTGATCCTCTTCCTGAAGATGGCCTCCGGGCACGCCTTCCAGCCTGACTTGGTTAAGAGGATCCGTGACGCCATCCGCATGGGCTTG
TCTGCGCGACACGTGCCCAGCCTCATCCTGGAAACCAAGGGCATCCCGTATACGCTCAACGGCAAGAAAGTGGAAGTTGCCGTCAAACAG
ATCATCGCTGGAAAAGCCGTGGAGCAAGGAGGTGCTTTCTCGAACCCCGAGACCCTGGATCTGTACCGGGACATCCCTGAGCTGCAGGGC
TTCTGAGTCAGACTGGCTGGCGTGTCACTCAGCCGCACCCGTGTGCACTGTAACTTTTGTGTGCTCAAGAAATTATACAGAAACCTACAG
CTGTTGTAAAAGGATGCTCGCACCAAGTGTTCTGTAGGCTTGGGGAGGGATCGTTTCTCTGTTTTGTTAAATCTGGTGGGTACCTGGATC
TTCCACACGAGTGGGATTCTGGCCTTCAGAGACCAGGAGGGAGTGTCTGGGCCGCAGGTGTGGCACTGTGGTGAGAGTGTGTGTCTTTGC
ACACACAGTGCAGCGGGAACGGTGGGGCTGGCTGGTGCTGAAGACAGACACACTCCTGAGCCAAGGTCTTGTCTTCAACCTCCCCGTCCC
GTTGTCCCATTTTGCTCTGTGAAGGTGCAAATCCCTTTCTTCCCTTCCCATCTCAGGCTCTCCTGTTTTCCCTCAGGGTCCAGTATGCCT
TTGAGCTTTAGCTGTTAGAAAGGAACCCCCGTGACTTGACACAGCTTTCACAGCTGGCTGCTAGGACCGGCGGGCTGGGTGTTCACGTGT
GTCTGTGTCATGGATGCAATGCAGGCCCTGGAGGACTGTGCGTCACCCGTCAACCAGAGCGTGCCTCCGGGCCAGCTTCCCTCCAAGGAA
TGAGTGGATTTCATACAGGATCTCTTTATTGCACAGACTGAATGGCTTTACATGTTTCTAATGTGAATTAGGCATGTGAAGCAGTGGGTG
TCCACCCGTGTCCCTCATGGGTGAGCCCTCCAGCTGTGAGCCCAGGCAGTGTGGTCACCGAGTGAGGACCCTCCTCACCAGGAACCGCAT
CCCTGTGCTGCCTCCACCTGAGAGTTGCTAGGGGGTTCTTGTCGAGATCATGTCATCAGCACCCCTAAGTCAAGTCACGGGTTTCCATAG
CCAGGCAGTTGGTATGTACAATTCAGTTCAGCGTATGAACTTGTATCTCTAATCTGATGTCCATTTTTATATTTTTTGAAACTGAGCACA
ATGAAATCCTTTCTTGAATCATTTTCCTTTTGGATTATAAAAATATGGGGGAAAGTGCTATGATGAATTTTATGCAATAAATGTATACAT

>79521_79521_8_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000415380_AACS_chr12_125599022_ENST00000316519_length(amino acids)=443AA_BP=74
MRARSPRLCRLCRRPRLLPGAEPCEPRVGPRRADMGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKGTLIQHLKEHLLHG
NMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILS
TGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGESGELVCTKPIPCQPTHFW
NDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKM

--------------------------------------------------------------
>79521_79521_9_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000546215_AACS_chr12_125599022_ENST00000261686_length(transcript)=2176nt_BP=189nt
CGTCCCCGTCTCCTGCCAGGCGCGGAGCCCTGCGAGCCGCGGGTGGGCCCCAGGCGCGCAGACATGGGCTGCTCCGCCAAAGCGCGCTGG
GCTGCCGGGGCGCTGGGCGTCGCGGGGCTACTGTGCGCTGTGCTGGGCGCTGTCATGATCGTGATGGTGCCGTCGCTCATCAAGCAGCAG
GTCCTTAAGGGCACCCTCATCCAGCATCTGAAGGAGCACCTGCTGCACGGCAACATGACCAGCAGTGACATCCTCCTGTGCTACACCACG
GTCGGCTGGATGATGTGGAACTGGATGGTGTCCCTTCTGGCCACAGGAGCGGCCATGGTCTTGTACGATGGCTCCCCCCTGGTGCCCACG
CCCAATGTGCTCTGGGACCTGGTTGACAGGATAGGCATCACTGTCCTGGTAACTGGGGCCAAGTGGCTGTCAGTGCTGGAAGAGAAGGCC
ATGAAGCCGGTGGAAACCCACAGTCTCCAGATGCTCCACACGATCCTGTCCACTGGCTCCCCACTGAAAGCCCAGAGCTACGAGTATGTC
TACAGGTGCATCAAGAGCAGCATCCTCCTGGGCTCCATCTCAGGAGGCACCGACATCATCTCCTGCTTCATGGGCCACAATTTTTCTCTT
CCTGTGTATAAAGGGGAGATTCAGGCCCGGAACCTGGGCATGGCCGTGGAAGCGTGGAACGAGGAAGGAAAGGCGGTCTGGGGAGAGAGC
GGCGAGCTGGTGTGTACTAAGCCGATCCCTTGCCAGCCCACACACTTCTGGAACGATGAGAACGGCAACAAGTACAGGAAGGCGTATTTC
TCCAAATTCCCAGGTATCTGGGCTCATGGCGACTACTGCAGAATCAACCCCAAGACCGGGGGCATCGTCATGCTTGGCCGGAGTGACGGC
ACCCTCAACCCCAACGGGGTGCGGTTCGGCAGCTCGGAAATCTATAACATTGTATACGCTCAACGGCAAGAAAGTGGAAGTTGCCGTCAA
ACAGATCATCGCTGGAAAAGCCGTGGAGCAAGGAGGTGCTTTCTCGAACCCCGAGACCCTGGATCTGTACCGGGACATCCCTGAGCTGCA
GGGCTTCTGAGTCAGACTGGCTGGCGTGTCACTCAGCCGCACCCGTGTGCACTGTAACTTTTGTGTGCTCAAGAAATTATACAGAAACCT
ACAGCTGTTGTAAAAGGATGCTCGCACCAAGTGTTCTGTAGGCTTGGGGAGGGATCGTTTCTCTGTTTTGTTAAATCTGGTGGGTACCTG
GATCTTCCACACGAGTGGGATTCTGGCCTTCAGAGACCAGGAGGGAGTGTCTGGGCCGCAGGTGTGGCACTGTGGTGAGAGTGTGTGTCT
TTGCACACACAGTGCAGCGGGAACGGTGGGGCTGGCTGGTGCTGAAGACAGACACACTCCTGAGCCAAGGTCTTGTCTTCAACCTCCCCG
TCCCGTTGTCCCATTTTGCTCTGTGAAGGTGCAAATCCCTTTCTTCCCTTCCCATCTCAGGCTCTCCTGTTTTCCCTCAGGGTCCAGTAT
GCCTTTGAGCTTTAGCTGTTAGAAAGGAACCCCCGTGACTTGACACAGCTTTCACAGCTGGCTGCTAGGACCGGCGGGCTGGGTGTTCAC
GTGTGTCTGTGTCATGGATGCAATGCAGGCCCTGGAGGACTGTGCGTCACCCGTCAACCAGAGCGTGCCTCCGGGCCAGCTTCCCTCCAA
GGAATGAGTGGATTTCATACAGGATCTCTTTATTGCACAGACTGAATGGCTTTACATGTTTCTAATGTGAATTAGGCATGTGAAGCAGTG
GGTGTCCACCCGTGTCCCTCATGGGTGAGCCCTCCAGCTGTGAGCCCAGGCAGTGTGGTCACCGAGTGAGGACCCTCCTCACCAGGAACC
GCATCCCTGTGCTGCCTCCACCTGAGAGTTGCTAGGGGGTTCTTGTCGAGATCATGTCATCAGCACCCCTAAGTCAAGTCACGGGTTTCC
ATAGCCAGGCAGTTGGTATGTACAATTCAGTTCAGCGTATGAACTTGTATCTCTAATCTGATGTCCATTTTTATATTTTTTGAAACTGAG
CACAATGAAATCCTTTCTTGAATCATTTTCCTTTTGGATTATAAAAATATGGGGGAAAGTGCTATGATGAATTTTATGCAATAAATGTAT

>79521_79521_9_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000546215_AACS_chr12_125599022_ENST00000261686_length(amino acids)=353AA_BP=57
MPGAEPCEPRVGPRRADMGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKGTLIQHLKEHLLHGNMTSSDILLCYTTVGWM
MWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCI
KSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFP

--------------------------------------------------------------
>79521_79521_10_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000546215_AACS_chr12_125599022_ENST00000316519_length(transcript)=2384nt_BP=189nt
CGTCCCCGTCTCCTGCCAGGCGCGGAGCCCTGCGAGCCGCGGGTGGGCCCCAGGCGCGCAGACATGGGCTGCTCCGCCAAAGCGCGCTGG
GCTGCCGGGGCGCTGGGCGTCGCGGGGCTACTGTGCGCTGTGCTGGGCGCTGTCATGATCGTGATGGTGCCGTCGCTCATCAAGCAGCAG
GTCCTTAAGGGCACCCTCATCCAGCATCTGAAGGAGCACCTGCTGCACGGCAACATGACCAGCAGTGACATCCTCCTGTGCTACACCACG
GTCGGCTGGATGATGTGGAACTGGATGGTGTCCCTTCTGGCCACAGGAGCGGCCATGGTCTTGTACGATGGCTCCCCCCTGGTGCCCACG
CCCAATGTGCTCTGGGACCTGGTTGACAGGATAGGCATCACTGTCCTGGTAACTGGGGCCAAGTGGCTGTCAGTGCTGGAAGAGAAGGCC
ATGAAGCCGGTGGAAACCCACAGTCTCCAGATGCTCCACACGATCCTGTCCACTGGCTCCCCACTGAAAGCCCAGAGCTACGAGTATGTC
TACAGGTGCATCAAGAGCAGCATCCTCCTGGGCTCCATCTCAGGAGGCACCGACATCATCTCCTGCTTCATGGGCCACAATTTTTCTCTT
CCTGTGTATAAAGGGGAGATTCAGGCCCGGAACCTGGGCATGGCCGTGGAAGCGTGGAACGAGGAAGGAAAGGCGGTCTGGGGAGAGAGC
GGCGAGCTGGTGTGTACTAAGCCGATCCCTTGCCAGCCCACACACTTCTGGAACGATGAGAACGGCAACAAGTACAGGAAGGCGTATTTC
TCCAAATTCCCAGGTATCTGGGCTCATGGCGACTACTGCAGAATCAACCCCAAGACCGGGGGCATCGTCATGCTTGGCCGGAGTGACGGC
ACCCTCAACCCCAACGGGGTGCGGTTCGGCAGCTCGGAAATCTATAACATTGTGGAATCCTTCGAGGAGGTGGAGGACAGCCTGTGTGTC
CCCCAGTATAACAAGTACAGGGAGGAGAGGGTGATCCTCTTCCTGAAGATGGCCTCCGGGCACGCCTTCCAGCCTGACTTGGTTAAGAGG
ATCCGTGACGCCATCCGCATGGGCTTGTCTGCGCGACACGTGCCCAGCCTCATCCTGGAAACCAAGGGCATCCCGTATACGCTCAACGGC
AAGAAAGTGGAAGTTGCCGTCAAACAGATCATCGCTGGAAAAGCCGTGGAGCAAGGAGGTGCTTTCTCGAACCCCGAGACCCTGGATCTG
TACCGGGACATCCCTGAGCTGCAGGGCTTCTGAGTCAGACTGGCTGGCGTGTCACTCAGCCGCACCCGTGTGCACTGTAACTTTTGTGTG
CTCAAGAAATTATACAGAAACCTACAGCTGTTGTAAAAGGATGCTCGCACCAAGTGTTCTGTAGGCTTGGGGAGGGATCGTTTCTCTGTT
TTGTTAAATCTGGTGGGTACCTGGATCTTCCACACGAGTGGGATTCTGGCCTTCAGAGACCAGGAGGGAGTGTCTGGGCCGCAGGTGTGG
CACTGTGGTGAGAGTGTGTGTCTTTGCACACACAGTGCAGCGGGAACGGTGGGGCTGGCTGGTGCTGAAGACAGACACACTCCTGAGCCA
AGGTCTTGTCTTCAACCTCCCCGTCCCGTTGTCCCATTTTGCTCTGTGAAGGTGCAAATCCCTTTCTTCCCTTCCCATCTCAGGCTCTCC
TGTTTTCCCTCAGGGTCCAGTATGCCTTTGAGCTTTAGCTGTTAGAAAGGAACCCCCGTGACTTGACACAGCTTTCACAGCTGGCTGCTA
GGACCGGCGGGCTGGGTGTTCACGTGTGTCTGTGTCATGGATGCAATGCAGGCCCTGGAGGACTGTGCGTCACCCGTCAACCAGAGCGTG
CCTCCGGGCCAGCTTCCCTCCAAGGAATGAGTGGATTTCATACAGGATCTCTTTATTGCACAGACTGAATGGCTTTACATGTTTCTAATG
TGAATTAGGCATGTGAAGCAGTGGGTGTCCACCCGTGTCCCTCATGGGTGAGCCCTCCAGCTGTGAGCCCAGGCAGTGTGGTCACCGAGT
GAGGACCCTCCTCACCAGGAACCGCATCCCTGTGCTGCCTCCACCTGAGAGTTGCTAGGGGGTTCTTGTCGAGATCATGTCATCAGCACC
CCTAAGTCAAGTCACGGGTTTCCATAGCCAGGCAGTTGGTATGTACAATTCAGTTCAGCGTATGAACTTGTATCTCTAATCTGATGTCCA
TTTTTATATTTTTTGAAACTGAGCACAATGAAATCCTTTCTTGAATCATTTTCCTTTTGGATTATAAAAATATGGGGGAAAGTGCTATGA

>79521_79521_10_SCARB1-AACS_SCARB1_chr12_125348140_ENST00000546215_AACS_chr12_125599022_ENST00000316519_length(amino acids)=426AA_BP=57
MPGAEPCEPRVGPRRADMGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKGTLIQHLKEHLLHGNMTSSDILLCYTTVGWM
MWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCI
KSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFP
GIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLVKRIRDA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SCARB1-AACS


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SCARB1-AACS


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SCARB1-AACS


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource