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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SCG5-FRMD5 (FusionGDB2 ID:79609)

Fusion Gene Summary for SCG5-FRMD5

check button Fusion gene summary
Fusion gene informationFusion gene name: SCG5-FRMD5
Fusion gene ID: 79609
HgeneTgene
Gene symbol

SCG5

FRMD5

Gene ID

6447

84978

Gene namesecretogranin VFERM domain containing 5
Synonyms7B2|P7B2|SGNE1|SgV-
Cytomap

15q13.3

15q15.3

Type of geneprotein-codingprotein-coding
Descriptionneuroendocrine protein 7B2pituitary polypeptideprohormone convertase chaperonesecretogranin-5secretory granule endocrine protein Isecretory granule, neuroendocrine protein 1 (7B2 protein)FERM domain-containing protein 5
Modification date2020031320200313
UniProtAcc.

Q7Z6J6

Ensembl transtripts involved in fusion geneENST00000498069, ENST00000300175, 
ENST00000413748, ENST00000494364, 
ENST00000497208, 		ENST00000402883, 
ENST00000417257, ENST00000484674, 
Fusion gene scores* DoF score2 X 2 X 2=815 X 17 X 5=1275
# samples 218
** MAII scorelog2(2/8*10)=1.32192809488736log2(18/1275*10)=-2.82442843541655
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SCG5 [Title/Abstract] AND FRMD5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSCG5(32976870)-FRMD5(44216507), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SCG5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FRMD5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-0745-01ASCG5chr15

32976870

+FRMD5chr15

44216507

-


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Fusion Gene ORF analysis for SCG5-FRMD5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000498069ENST00000402883SCG5chr15

32976870

+FRMD5chr15

44216507

-
3UTR-3CDSENST00000498069ENST00000417257SCG5chr15

32976870

+FRMD5chr15

44216507

-
3UTR-5UTRENST00000498069ENST00000484674SCG5chr15

32976870

+FRMD5chr15

44216507

-
5CDS-5UTRENST00000300175ENST00000484674SCG5chr15

32976870

+FRMD5chr15

44216507

-
5CDS-5UTRENST00000413748ENST00000484674SCG5chr15

32976870

+FRMD5chr15

44216507

-
5CDS-5UTRENST00000494364ENST00000484674SCG5chr15

32976870

+FRMD5chr15

44216507

-
5CDS-5UTRENST00000497208ENST00000484674SCG5chr15

32976870

+FRMD5chr15

44216507

-
In-frameENST00000300175ENST00000402883SCG5chr15

32976870

+FRMD5chr15

44216507

-
In-frameENST00000300175ENST00000417257SCG5chr15

32976870

+FRMD5chr15

44216507

-
In-frameENST00000413748ENST00000402883SCG5chr15

32976870

+FRMD5chr15

44216507

-
In-frameENST00000413748ENST00000417257SCG5chr15

32976870

+FRMD5chr15

44216507

-
In-frameENST00000494364ENST00000402883SCG5chr15

32976870

+FRMD5chr15

44216507

-
In-frameENST00000494364ENST00000417257SCG5chr15

32976870

+FRMD5chr15

44216507

-
In-frameENST00000497208ENST00000402883SCG5chr15

32976870

+FRMD5chr15

44216507

-
In-frameENST00000497208ENST00000417257SCG5chr15

32976870

+FRMD5chr15

44216507

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000413748SCG5chr1532976870+ENST00000417257FRMD5chr1544216507-53285961042206700
ENST00000413748SCG5chr1532976870+ENST00000402883FRMD5chr1544216507-44295961042047647
ENST00000300175SCG5chr1532976870+ENST00000417257FRMD5chr1544216507-53315991042209701
ENST00000300175SCG5chr1532976870+ENST00000402883FRMD5chr1544216507-44325991042050648
ENST00000494364SCG5chr1532976870+ENST00000417257FRMD5chr1544216507-5305573812183700
ENST00000494364SCG5chr1532976870+ENST00000402883FRMD5chr1544216507-4406573812024647
ENST00000497208SCG5chr1532976870+ENST00000417257FRMD5chr1544216507-5305573782183701
ENST00000497208SCG5chr1532976870+ENST00000402883FRMD5chr1544216507-4406573782024648

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000413748ENST00000417257SCG5chr1532976870+FRMD5chr1544216507-0.0019257590.9980742
ENST00000413748ENST00000402883SCG5chr1532976870+FRMD5chr1544216507-0.0019148110.99808526
ENST00000300175ENST00000417257SCG5chr1532976870+FRMD5chr1544216507-0.0021007730.9978992
ENST00000300175ENST00000402883SCG5chr1532976870+FRMD5chr1544216507-0.0020404140.9979596
ENST00000494364ENST00000417257SCG5chr1532976870+FRMD5chr1544216507-0.0019346750.9980653
ENST00000494364ENST00000402883SCG5chr1532976870+FRMD5chr1544216507-0.0019345740.9980654
ENST00000497208ENST00000417257SCG5chr1532976870+FRMD5chr1544216507-0.0020935560.99790645
ENST00000497208ENST00000402883SCG5chr1532976870+FRMD5chr1544216507-0.0020179090.997982

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Fusion Genomic Features for SCG5-FRMD5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SCG5-FRMD5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:32976870/chr15:44216507)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FRMD5

Q7Z6J6

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May be involved in regulation of cell migration (PubMed:22846708, PubMed:25448675). May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation (PubMed:25448675).

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFRMD5chr15:32976870chr15:44216507ENST00000417257014504_52434571.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFRMD5chr15:32976870chr15:44216507ENST0000041725701417_29834571.0DomainFERM


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Fusion Gene Sequence for SCG5-FRMD5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>79609_79609_1_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000300175_FRMD5_chr15_44216507_ENST00000402883_length(transcript)=4432nt_BP=599nt
TAAGATGCGGAGGAGGGTGACGCACTAGCTCTCCAGTTCGCCCGTTCCTGGCCTGACCCCCACCAAGGCCCATACCGCAGTAGGCTCCTC
GGGCTGCCCCTCGGTTGACAATGGTCTCCAGGATGGTCTCTACCATGCTATCTGGCCTACTGTTTTGGCTGGCATCTGGATGGACTCCAG
CATTTGCTTACAGCCCCCGGACCCCTGACCGGGTCTCAGAAGCAGATATCCAGAGGCTGCTTCATGGTGTTATGGAGCAATTGGGCATTG
CCAGGCCCCGAGTGGAATATCCAGCTCACCAGGCCATGAATCTTGTGGGCCCCCAGAGCATTGAAGGTGGAGCTCATGAAGGACTTCAGC
ATTTGGGTCCTTTTGGCAACATCCCCAACATCGTGGCAGAGTTGACTGGAGACAACATTCCTAAGGACTTTAGTGAGGATCAGGGGTACC
CAGACCCTCCAAATCCCTGTCCTGTTGGAAAAACAGCAGATGATGGATGTCTAGAAAACACCCCTGACACTGCAGAGTTCAGTCGAGAGT
TCCAGTTGCACCAGCATCTCTTTGATCCGGAACATGACTATCCAGGCTTGGGCAAGTGGAGAGATGCCAAAGGCCAGTACCTGTTTGACC
TTCTTTGCCACCATCTGAACCTACTTGAGAAAGACTATTTTGGTATCCGCTTTGTAGACCCAGATAAGCAGCGGCATTGGCTGGAATTTA
CAAAGTCTGTGGTGAAACAATTGAGATCCCAGCCTCCATTCACCATGTGCTTCCGTGTGAAGTTTTATCCTGCAGACCCTGCTGCTCTGA
AAGAAGAAATAACCAGGTATTTAGTCTTCCTGCAGATCAAAAGGGATCTCTACCATGGCCGACTCCTCTGTAAAACATCGGATGCTGCCT
TGTTAGCAGCTTACATCCTTCAAGCGGAGATTGGGGATTATGACTCAGGGAAACACCCTGAAGGCTACAGCTCCAAGTTCCAGTTTTTCC
CTAAACATTCAGAGAAGCTGGAAAGGAAAATTGCTGAGATTCACAAGACGGAACTGAGTGGTCAAACACCAGCAACATCAGAGCTGAACT
TCTTAAGAAAAGCACAGACATTGGAAACATATGGAGTGGATCCTCACCCATGTAAGGACGTGTCAGGAAATGCTGCATTTCTGGCCTTCA
CTCCTTTTGGGTTTGTTGTTCTTCAAGGAAACAAGAGGGTCCACTTCATTAAATGGAATGAGGTGACCAAGCTGAAATTTGAAGGAAAGA
CTTTCTATTTATACGTAAGTCAGAAAGAGGAAAAGAAAATTATTCTTACATATTTTGCTCCAACTCCTGAAGCGTGTAAGCACCTCTGGA
AATGTGGAATCGAGAACCAAGCCTTCTACAAGCTGGAGAAGTCAAGCCAAGTCCGCACAGTGTCCAGCAGCAATTTATTCTTTAAAGGGA
GCCGGTTCCGATACAGTGGCCGAGTTGCAAAGGAAGTCATGGAATCAAGTGCTAAGATCAAACGGGAGCCACCGGAAATACACAGAGCAG
GGATGGTTCCCAGCCGGAGCTGTCCCTCCATAACCCATGGCCCAAGGCTGAGCAGCGTCCCCAGGACCCGCAGAAGAGCTGTTCACATCT
CCATCATGGAAGGCCTAGAGTCCTTACGGGACAGTGCCCATTCCACACCAGTGCGTTCCACTTCCCATGGGGACACCTTCCTGCCTCACG
TGAGAAGCAGCCGGACAGATAGCAATGAGCGAGTAGCTGTGATTGCAGACGAGGCCTACAGCCCTGCAGACAGCGTGCTGCCCACCCCTG
TGGCTGAGCACAGCCTGGAGCTGATGTTGCTTTCCCGGCAGATCAATGGAGCCACCTGCAGCATTGAGGAGGAGAAGGAATCTGAAGCCA
GCACCCCAACTGCTACAGAGGTGGAGGCCCTTGGGGGAGAGCTGAGGGCCCTGTGTCAGGGGCACAGCGGGCCCGAGGAGGAACAGAGTG
GGCATCTGAAGGGACCACCGCTACAGCAACAGCAGCATCAGGGGTGGGGTAAGTCTGTCCCCTTAGTCTAGAGCCTAGTGGGCATCACCA
TAGTTTTGTATAATGAAACTAGACTTAACGTGATTTTTTTTTTCCGAAGAACCTCAAGACTTTTATAGTGCTCCAGGGGCGTTAAACGAA
TTCAGTGGTACCAGAGATAGATAGTTCTGTCAGAAATGTTGGACAAAGTGTAGTTAAGAGAAAGCAGAGTTAAGTTACCTGAGAGACTGT
TGAGATTTGGATAGCAGTGCTTATTTTATATACACCCCCTTGACCCAAAGACTATTTCAATTTATATTTTAACAACGAAATGTTATTTTC
TTAACAATTCATATTTTGTTTTTACTTTATGGATTAAGAAAATAGAGCCTGATGAACTAAACGATGCAAGAAAGAAACTGATCCTGAGAA
TGAAAAGCTTCAGAAAATAGAATTCCAAGATCAACAGCCTTAGAAGGGACCAGGAAAAGAATCTTTTAAAATAGATTTCTAAGAGATGCC
TACAAAACACAGAATGTGACCGTGGCAGAGACCAACACTTAGATGTAGAAATGCTGCCCCCTAGGGTCATCCTCTGCATAAGTTCTAGGA
AAGCATCACCATCCTTGCAGAGGGAAGTCCTCGAAGCACGCAGCACAGGCATATGAAGGGCGAGTGTGGGATCCTAGGCCCAAGCTCTTC
AACTCTAAAACCAATCACACACAAGATCCTGTTTTCATCTCAGGGAGAGATTTCTAAGTCATCTGGGGCTTGAGGGCTTATTTAAGGGTG
GTCAATGGACATATTCCTGGACCCACACAAAAGTAGAGCAGCTGCTGATACCCTAATTGGACAGCCCCAAACGCAGAACAGAACAAGTCA
CTTGTAGACTTGACCTCCCCTATTTTGTCCCCCGAGATGGTAGAACCATGTCCATGTTTACAATATGACAACTGTGGAATAATTGGGGTT
CTTAGGGAGAGATTTGCATAATTTTAAAGACATCCTTTCATCTGGACCAGAGGTCAATCAACTTATGTCAAGTGCTACACAGTAAATATT
TTGGTTTAGCACGCCATACTGTGTCACAACTGCTCAATTCTGCCATCACAGCACAAAAACAGCCACAGATAATTTGTAAATGAAGGAACA
TGGCTGTGTTCCAATAAAACTTTATGAAAACAGTGAGCTGAATTTAGCCTACAGGCCATAATACGCCAATCCTGCTCTAGACAATAAAAC
TGATCCTTACCAGTATGTTAGCAGAAGAGGGTCAGTCAGCTCTGTTTCCATGCCTGACATGTATCAAAGATCTGGGACCTCTTCCCAGTG
GAGGCACTAGGGTTGCTTGTTTAAAGGGTGCTTGAACAACTAACCAGCAAAGAGATGTCTGATGCCAAATGGGCAAGATCAAATACTGGA
ATGCTAAAACACAGCTGGAATCTAAGAAGGGAAGAGGGCTTCTCTGACCATTTTCATACCAGCAACAATTTAGGCAGAATTATAAACATC
TATTTATCGAGTGACAATACAAACCGAAGGAGATCCTAGTAGAGATTAGGGGTCAGTTAAAATCAACTAGCCACTGCCACTTGTCATCTA
CATAGCAAAGGCTTTATTTAGCACAGGACTAACGTGAAAAGTAGACCCAGAGATGAAAAGGCTGTCAGGAGACAGGGGGCTGGTGTCCAC
CTGGTATCTACTGTCTTATGCAACATAGAAGATTACCTTTTAGTGTAGTGCTCCTACCTCAGTTTGTAGAATCTGGTGTTTCTATGCAGT
GAGTGATAGCCTCAACTCTGACCTTTCATATTCACATTAGAGACAGATGCAGTATTCCATATCCTAGTATGTTCCTTGTGTCTAGAGTTC
TAACAGTACAGTAGTCTATGCCATTTCTAACAGCTAAATTTTGCTCTGTAAACAGAAACTTTAGGGTTGTTTTTTTCCAGGGCTCATCCC
AGAAAATATGGATAGAAAAGTTTCCTTCAGTTTGCTTTTCAAATAGTGCTTGAATAATAAACCTCCTTTGATTGGTGACTAGTCTTTTTT
GGTATATCTCCACCTTTAAAAATTGTTCAAGTTTTTAACCTGGTTATACTGTGTTCTAACATGTCTCTCATTTTCTCTCAAAATTAGTTT
ATCTCATTGTAGAAAAAGCAATGGTTTTCATAGCTTCATCTATCAGGAAATAAAACTCTTACTAAAGAATAGCATACTGCATCTTTAAGC
AGTAGAGGGTAAACTACCTGCAAATGTGAATTTCTTAGATACATTTAAAAATATATAGTTGTTAACCTTCTGTGTGCCAAAAACTCTTAA
GTTACATTTTCCTTCAAAGCAATGTACTTTTTTCTACATATGCAGTATGTAGTTAGCATAAAATCATTGGTGCCATGAAGATTATTTTTA

>79609_79609_1_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000300175_FRMD5_chr15_44216507_ENST00000402883_length(amino acids)=648AA_BP=165
MTMVSRMVSTMLSGLLFWLASGWTPAFAYSPRTPDRVSEADIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPF
GNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPVGKTADDGCLENTPDTAEFSREFQLHQHLFDPEHDYPGLGKWRDAKGQYLFDLLCHH
LNLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAY
ILQAEIGDYDSGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGF
VVLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRY
SGRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSTSHGDTFLPHVRSSR
TDSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEVEALGGELRALCQGHSGPEEEQSGHLKG

--------------------------------------------------------------
>79609_79609_2_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000300175_FRMD5_chr15_44216507_ENST00000417257_length(transcript)=5331nt_BP=599nt
TAAGATGCGGAGGAGGGTGACGCACTAGCTCTCCAGTTCGCCCGTTCCTGGCCTGACCCCCACCAAGGCCCATACCGCAGTAGGCTCCTC
GGGCTGCCCCTCGGTTGACAATGGTCTCCAGGATGGTCTCTACCATGCTATCTGGCCTACTGTTTTGGCTGGCATCTGGATGGACTCCAG
CATTTGCTTACAGCCCCCGGACCCCTGACCGGGTCTCAGAAGCAGATATCCAGAGGCTGCTTCATGGTGTTATGGAGCAATTGGGCATTG
CCAGGCCCCGAGTGGAATATCCAGCTCACCAGGCCATGAATCTTGTGGGCCCCCAGAGCATTGAAGGTGGAGCTCATGAAGGACTTCAGC
ATTTGGGTCCTTTTGGCAACATCCCCAACATCGTGGCAGAGTTGACTGGAGACAACATTCCTAAGGACTTTAGTGAGGATCAGGGGTACC
CAGACCCTCCAAATCCCTGTCCTGTTGGAAAAACAGCAGATGATGGATGTCTAGAAAACACCCCTGACACTGCAGAGTTCAGTCGAGAGT
TCCAGTTGCACCAGCATCTCTTTGATCCGGAACATGACTATCCAGGCTTGGGCAAGTGGAGAGATGCCAAAGGCCAGTACCTGTTTGACC
TTCTTTGCCACCATCTGAACCTACTTGAGAAAGACTATTTTGGTATCCGCTTTGTAGACCCAGATAAGCAGCGGCATTGGCTGGAATTTA
CAAAGTCTGTGGTGAAACAATTGAGATCCCAGCCTCCATTCACCATGTGCTTCCGTGTGAAGTTTTATCCTGCAGACCCTGCTGCTCTGA
AAGAAGAAATAACCAGGTATTTAGTCTTCCTGCAGATCAAAAGGGATCTCTACCATGGCCGACTCCTCTGTAAAACATCGGATGCTGCCT
TGTTAGCAGCTTACATCCTTCAAGCGGAGATTGGGGATTATGACTCAGGGAAACACCCTGAAGGCTACAGCTCCAAGTTCCAGTTTTTCC
CTAAACATTCAGAGAAGCTGGAAAGGAAAATTGCTGAGATTCACAAGACGGAACTGAGTGGTCAAACACCAGCAACATCAGAGCTGAACT
TCTTAAGAAAAGCACAGACATTGGAAACATATGGAGTGGATCCTCACCCATGTAAGGACGTGTCAGGAAATGCTGCATTTCTGGCCTTCA
CTCCTTTTGGGTTTGTTGTTCTTCAAGGAAACAAGAGGGTCCACTTCATTAAATGGAATGAGGTGACCAAGCTGAAATTTGAAGGAAAGA
CTTTCTATTTATACGTAAGTCAGAAAGAGGAAAAGAAAATTATTCTTACATATTTTGCTCCAACTCCTGAAGCGTGTAAGCACCTCTGGA
AATGTGGAATCGAGAACCAAGCCTTCTACAAGCTGGAGAAGTCAAGCCAAGTCCGCACAGTGTCCAGCAGCAATTTATTCTTTAAAGGGA
GCCGGTTCCGATACAGTGGCCGAGTTGCAAAGGAAGTCATGGAATCAAGTGCTAAGATCAAACGGGAGCCACCGGAAATACACAGAGCAG
GGATGGTTCCCAGCCGGAGCTGTCCCTCCATAACCCATGGCCCAAGGCTGAGCAGCGTCCCCAGGACCCGCAGAAGAGCTGTTCACATCT
CCATCATGGAAGGCCTAGAGTCCTTACGGGACAGTGCCCATTCCACACCAGTGCGTTCCACTTCCCATGGGGACACCTTCCTGCCTCACG
TGAGAAGCAGCCGGACAGATAGCAATGAGCGAGTAGCTGTGATTGCAGACGAGGCCTACAGCCCTGCAGACAGCGTGCTGCCCACCCCTG
TGGCTGAGCACAGCCTGGAGCTGATGTTGCTTTCCCGGCAGATCAATGGAGCCACCTGCAGCATTGAGGAGGAGAAGGAATCTGAAGCCA
GCACCCCAACTGCTACAGAGGTGGAGGCCCTTGGGGGAGAGCTGAGGGCCCTGTGTCAGGGGCACAGCGGGCCCGAGGAGGAACAGGTGA
ATAAGTTTGTTCTAAGTGTCCTCCGTTTGCTCCTTGTGACCATGGGACTCCTCTTTGTTTTGCTCCTCCTCCTGATCATCCTTACCGAGT
CTGACCTTGACATTGCCTTTTTCCGTGATATCCGCCAGACCCCCGAGTTTGAACAATTCCACTATCAATACTTTTGTCCCCTCAGGCGAT
GGTTTGCCTGCAAAATCCGCTCAGTGGTGAGCCTGCTCATTGACACCTGAGAAGGCATGACTCCTCCCAAAAACTAGCCAGGTGGACCAA
GGAACCCGGCTACCCATTCCCAGCAATGGGACCCATCGCGGAACCATCGGCACATATACCAAGTCCTCCTCTCATGACTCAAAGTCCACT
GCAGCCTAGGAGGGTGTTTCCCAGAAGAAGAAAGGGATAGGCTCATGCCCTGTCTAAACAAACTGGGAAAACTCATTTTCTTCAGAAGTT
ATTTCAAGAAAGGCTCAGCGACTCTGTTTCTCATCTTTCCAATTTGCAGGATAATTTTTGGTTTTGAATTTTGATTTTTCATAGATGTAT
ATTATTTTGAAGTATCAAATAAAAATAATTTATTTTACTATTACTGATTATTGCAGTAGTATCACCTAGCAGAGGGGACACTAGTTGAAA
ACTAGAGAGCTGCTGTCCTCTGTATTCTGCAGGAGCTTTTCCTGCTGGTGCCACTGGGTTCCAGTAGACTCATCACTGCAGCCTCAGCAG
GGCAGGCCAGGGATCTGGACAATGGGGACTGTTTAGTTTTTTGTTTGTTTTTTTTGCCAGCCAGAACTTTTAAAAAAGTAAACATCCATG
TAGAATGATTAAATGGAAAGTTGCTTCTTATGATGGTCTGAGTTGGATTTTCTTTTCCTTTTGTTTTTTCAAATCTGAGCAGAGTGGGCA
TCTGAAGGGACCACCGCTACAGCAACAGCAGCATCAGGGGTGGGGTAAGTCTGTCCCCTTAGTCTAGAGCCTAGTGGGCATCACCATAGT
TTTGTATAATGAAACTAGACTTAACGTGATTTTTTTTTTCCGAAGAACCTCAAGACTTTTATAGTGCTCCAGGGGCGTTAAACGAATTCA
GTGGTACCAGAGATAGATAGTTCTGTCAGAAATGTTGGACAAAGTGTAGTTAAGAGAAAGCAGAGTTAAGTTACCTGAGAGACTGTTGAG
ATTTGGATAGCAGTGCTTATTTTATATACACCCCCTTGACCCAAAGACTATTTCAATTTATATTTTAACAACGAAATGTTATTTTCTTAA
CAATTCATATTTTGTTTTTACTTTATGGATTAAGAAAATAGAGCCTGATGAACTAAACGATGCAAGAAAGAAACTGATCCTGAGAATGAA
AAGCTTCAGAAAATAGAATTCCAAGATCAACAGCCTTAGAAGGGACCAGGAAAAGAATCTTTTAAAATAGATTTCTAAGAGATGCCTACA
AAACACAGAATGTGACCGTGGCAGAGACCAACACTTAGATGTAGAAATGCTGCCCCCTAGGGTCATCCTCTGCATAAGTTCTAGGAAAGC
ATCACCATCCTTGCAGAGGGAAGTCCTCGAAGCACGCAGCACAGGCATATGAAGGGCGAGTGTGGGATCCTAGGCCCAAGCTCTTCAACT
CTAAAACCAATCACACACAAGATCCTGTTTTCATCTCAGGGAGAGATTTCTAAGTCATCTGGGGCTTGAGGGCTTATTTAAGGGTGGTCA
ATGGACATATTCCTGGACCCACACAAAAGTAGAGCAGCTGCTGATACCCTAATTGGACAGCCCCAAACGCAGAACAGAACAAGTCACTTG
TAGACTTGACCTCCCCTATTTTGTCCCCCGAGATGGTAGAACCATGTCCATGTTTACAATATGACAACTGTGGAATAATTGGGGTTCTTA
GGGAGAGATTTGCATAATTTTAAAGACATCCTTTCATCTGGACCAGAGGTCAATCAACTTATGTCAAGTGCTACACAGTAAATATTTTGG
TTTAGCACGCCATACTGTGTCACAACTGCTCAATTCTGCCATCACAGCACAAAAACAGCCACAGATAATTTGTAAATGAAGGAACATGGC
TGTGTTCCAATAAAACTTTATGAAAACAGTGAGCTGAATTTAGCCTACAGGCCATAATACGCCAATCCTGCTCTAGACAATAAAACTGAT
CCTTACCAGTATGTTAGCAGAAGAGGGTCAGTCAGCTCTGTTTCCATGCCTGACATGTATCAAAGATCTGGGACCTCTTCCCAGTGGAGG
CACTAGGGTTGCTTGTTTAAAGGGTGCTTGAACAACTAACCAGCAAAGAGATGTCTGATGCCAAATGGGCAAGATCAAATACTGGAATGC
TAAAACACAGCTGGAATCTAAGAAGGGAAGAGGGCTTCTCTGACCATTTTCATACCAGCAACAATTTAGGCAGAATTATAAACATCTATT
TATCGAGTGACAATACAAACCGAAGGAGATCCTAGTAGAGATTAGGGGTCAGTTAAAATCAACTAGCCACTGCCACTTGTCATCTACATA
GCAAAGGCTTTATTTAGCACAGGACTAACGTGAAAAGTAGACCCAGAGATGAAAAGGCTGTCAGGAGACAGGGGGCTGGTGTCCACCTGG
TATCTACTGTCTTATGCAACATAGAAGATTACCTTTTAGTGTAGTGCTCCTACCTCAGTTTGTAGAATCTGGTGTTTCTATGCAGTGAGT
GATAGCCTCAACTCTGACCTTTCATATTCACATTAGAGACAGATGCAGTATTCCATATCCTAGTATGTTCCTTGTGTCTAGAGTTCTAAC
AGTACAGTAGTCTATGCCATTTCTAACAGCTAAATTTTGCTCTGTAAACAGAAACTTTAGGGTTGTTTTTTTCCAGGGCTCATCCCAGAA
AATATGGATAGAAAAGTTTCCTTCAGTTTGCTTTTCAAATAGTGCTTGAATAATAAACCTCCTTTGATTGGTGACTAGTCTTTTTTGGTA
TATCTCCACCTTTAAAAATTGTTCAAGTTTTTAACCTGGTTATACTGTGTTCTAACATGTCTCTCATTTTCTCTCAAAATTAGTTTATCT
CATTGTAGAAAAAGCAATGGTTTTCATAGCTTCATCTATCAGGAAATAAAACTCTTACTAAAGAATAGCATACTGCATCTTTAAGCAGTA
GAGGGTAAACTACCTGCAAATGTGAATTTCTTAGATACATTTAAAAATATATAGTTGTTAACCTTCTGTGTGCCAAAAACTCTTAAGTTA
CATTTTCCTTCAAAGCAATGTACTTTTTTCTACATATGCAGTATGTAGTTAGCATAAAATCATTGGTGCCATGAAGATTATTTTTAAACT

>79609_79609_2_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000300175_FRMD5_chr15_44216507_ENST00000417257_length(amino acids)=701AA_BP=165
MTMVSRMVSTMLSGLLFWLASGWTPAFAYSPRTPDRVSEADIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPF
GNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPVGKTADDGCLENTPDTAEFSREFQLHQHLFDPEHDYPGLGKWRDAKGQYLFDLLCHH
LNLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAY
ILQAEIGDYDSGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGF
VVLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRY
SGRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSTSHGDTFLPHVRSSR
TDSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEVEALGGELRALCQGHSGPEEEQVNKFVL

--------------------------------------------------------------
>79609_79609_3_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000413748_FRMD5_chr15_44216507_ENST00000402883_length(transcript)=4429nt_BP=596nt
TAAGATGCGGAGGAGGGTGACGCACTAGCTCTCCAGTTCGCCCGTTCCTGGCCTGACCCCCACCAAGGCCCATACCGCAGTAGGCTCCTC
GGGCTGCCCCTCGGTTGACAATGGTCTCCAGGATGGTCTCTACCATGCTATCTGGCCTACTGTTTTGGCTGGCATCTGGATGGACTCCAG
CATTTGCTTACAGCCCCCGGACCCCTGACCGGGTCTCAGAAGCAGATATCCAGAGGCTGCTTCATGGTGTTATGGAGCAATTGGGCATTG
CCAGGCCCCGAGTGGAATATCCAGCTCACCAGGCCATGAATCTTGTGGGCCCCCAGAGCATTGAAGGTGGAGCTCATGAAGGACTTCAGC
ATTTGGGTCCTTTTGGCAACATCCCCAACATCGTGGCAGAGTTGACTGGAGACAACATTCCTAAGGACTTTAGTGAGGATCAGGGGTACC
CAGACCCTCCAAATCCCTGTCCTGTTGGAAAAACAGATGATGGATGTCTAGAAAACACCCCTGACACTGCAGAGTTCAGTCGAGAGTTCC
AGTTGCACCAGCATCTCTTTGATCCGGAACATGACTATCCAGGCTTGGGCAAGTGGAGAGATGCCAAAGGCCAGTACCTGTTTGACCTTC
TTTGCCACCATCTGAACCTACTTGAGAAAGACTATTTTGGTATCCGCTTTGTAGACCCAGATAAGCAGCGGCATTGGCTGGAATTTACAA
AGTCTGTGGTGAAACAATTGAGATCCCAGCCTCCATTCACCATGTGCTTCCGTGTGAAGTTTTATCCTGCAGACCCTGCTGCTCTGAAAG
AAGAAATAACCAGGTATTTAGTCTTCCTGCAGATCAAAAGGGATCTCTACCATGGCCGACTCCTCTGTAAAACATCGGATGCTGCCTTGT
TAGCAGCTTACATCCTTCAAGCGGAGATTGGGGATTATGACTCAGGGAAACACCCTGAAGGCTACAGCTCCAAGTTCCAGTTTTTCCCTA
AACATTCAGAGAAGCTGGAAAGGAAAATTGCTGAGATTCACAAGACGGAACTGAGTGGTCAAACACCAGCAACATCAGAGCTGAACTTCT
TAAGAAAAGCACAGACATTGGAAACATATGGAGTGGATCCTCACCCATGTAAGGACGTGTCAGGAAATGCTGCATTTCTGGCCTTCACTC
CTTTTGGGTTTGTTGTTCTTCAAGGAAACAAGAGGGTCCACTTCATTAAATGGAATGAGGTGACCAAGCTGAAATTTGAAGGAAAGACTT
TCTATTTATACGTAAGTCAGAAAGAGGAAAAGAAAATTATTCTTACATATTTTGCTCCAACTCCTGAAGCGTGTAAGCACCTCTGGAAAT
GTGGAATCGAGAACCAAGCCTTCTACAAGCTGGAGAAGTCAAGCCAAGTCCGCACAGTGTCCAGCAGCAATTTATTCTTTAAAGGGAGCC
GGTTCCGATACAGTGGCCGAGTTGCAAAGGAAGTCATGGAATCAAGTGCTAAGATCAAACGGGAGCCACCGGAAATACACAGAGCAGGGA
TGGTTCCCAGCCGGAGCTGTCCCTCCATAACCCATGGCCCAAGGCTGAGCAGCGTCCCCAGGACCCGCAGAAGAGCTGTTCACATCTCCA
TCATGGAAGGCCTAGAGTCCTTACGGGACAGTGCCCATTCCACACCAGTGCGTTCCACTTCCCATGGGGACACCTTCCTGCCTCACGTGA
GAAGCAGCCGGACAGATAGCAATGAGCGAGTAGCTGTGATTGCAGACGAGGCCTACAGCCCTGCAGACAGCGTGCTGCCCACCCCTGTGG
CTGAGCACAGCCTGGAGCTGATGTTGCTTTCCCGGCAGATCAATGGAGCCACCTGCAGCATTGAGGAGGAGAAGGAATCTGAAGCCAGCA
CCCCAACTGCTACAGAGGTGGAGGCCCTTGGGGGAGAGCTGAGGGCCCTGTGTCAGGGGCACAGCGGGCCCGAGGAGGAACAGAGTGGGC
ATCTGAAGGGACCACCGCTACAGCAACAGCAGCATCAGGGGTGGGGTAAGTCTGTCCCCTTAGTCTAGAGCCTAGTGGGCATCACCATAG
TTTTGTATAATGAAACTAGACTTAACGTGATTTTTTTTTTCCGAAGAACCTCAAGACTTTTATAGTGCTCCAGGGGCGTTAAACGAATTC
AGTGGTACCAGAGATAGATAGTTCTGTCAGAAATGTTGGACAAAGTGTAGTTAAGAGAAAGCAGAGTTAAGTTACCTGAGAGACTGTTGA
GATTTGGATAGCAGTGCTTATTTTATATACACCCCCTTGACCCAAAGACTATTTCAATTTATATTTTAACAACGAAATGTTATTTTCTTA
ACAATTCATATTTTGTTTTTACTTTATGGATTAAGAAAATAGAGCCTGATGAACTAAACGATGCAAGAAAGAAACTGATCCTGAGAATGA
AAAGCTTCAGAAAATAGAATTCCAAGATCAACAGCCTTAGAAGGGACCAGGAAAAGAATCTTTTAAAATAGATTTCTAAGAGATGCCTAC
AAAACACAGAATGTGACCGTGGCAGAGACCAACACTTAGATGTAGAAATGCTGCCCCCTAGGGTCATCCTCTGCATAAGTTCTAGGAAAG
CATCACCATCCTTGCAGAGGGAAGTCCTCGAAGCACGCAGCACAGGCATATGAAGGGCGAGTGTGGGATCCTAGGCCCAAGCTCTTCAAC
TCTAAAACCAATCACACACAAGATCCTGTTTTCATCTCAGGGAGAGATTTCTAAGTCATCTGGGGCTTGAGGGCTTATTTAAGGGTGGTC
AATGGACATATTCCTGGACCCACACAAAAGTAGAGCAGCTGCTGATACCCTAATTGGACAGCCCCAAACGCAGAACAGAACAAGTCACTT
GTAGACTTGACCTCCCCTATTTTGTCCCCCGAGATGGTAGAACCATGTCCATGTTTACAATATGACAACTGTGGAATAATTGGGGTTCTT
AGGGAGAGATTTGCATAATTTTAAAGACATCCTTTCATCTGGACCAGAGGTCAATCAACTTATGTCAAGTGCTACACAGTAAATATTTTG
GTTTAGCACGCCATACTGTGTCACAACTGCTCAATTCTGCCATCACAGCACAAAAACAGCCACAGATAATTTGTAAATGAAGGAACATGG
CTGTGTTCCAATAAAACTTTATGAAAACAGTGAGCTGAATTTAGCCTACAGGCCATAATACGCCAATCCTGCTCTAGACAATAAAACTGA
TCCTTACCAGTATGTTAGCAGAAGAGGGTCAGTCAGCTCTGTTTCCATGCCTGACATGTATCAAAGATCTGGGACCTCTTCCCAGTGGAG
GCACTAGGGTTGCTTGTTTAAAGGGTGCTTGAACAACTAACCAGCAAAGAGATGTCTGATGCCAAATGGGCAAGATCAAATACTGGAATG
CTAAAACACAGCTGGAATCTAAGAAGGGAAGAGGGCTTCTCTGACCATTTTCATACCAGCAACAATTTAGGCAGAATTATAAACATCTAT
TTATCGAGTGACAATACAAACCGAAGGAGATCCTAGTAGAGATTAGGGGTCAGTTAAAATCAACTAGCCACTGCCACTTGTCATCTACAT
AGCAAAGGCTTTATTTAGCACAGGACTAACGTGAAAAGTAGACCCAGAGATGAAAAGGCTGTCAGGAGACAGGGGGCTGGTGTCCACCTG
GTATCTACTGTCTTATGCAACATAGAAGATTACCTTTTAGTGTAGTGCTCCTACCTCAGTTTGTAGAATCTGGTGTTTCTATGCAGTGAG
TGATAGCCTCAACTCTGACCTTTCATATTCACATTAGAGACAGATGCAGTATTCCATATCCTAGTATGTTCCTTGTGTCTAGAGTTCTAA
CAGTACAGTAGTCTATGCCATTTCTAACAGCTAAATTTTGCTCTGTAAACAGAAACTTTAGGGTTGTTTTTTTCCAGGGCTCATCCCAGA
AAATATGGATAGAAAAGTTTCCTTCAGTTTGCTTTTCAAATAGTGCTTGAATAATAAACCTCCTTTGATTGGTGACTAGTCTTTTTTGGT
ATATCTCCACCTTTAAAAATTGTTCAAGTTTTTAACCTGGTTATACTGTGTTCTAACATGTCTCTCATTTTCTCTCAAAATTAGTTTATC
TCATTGTAGAAAAAGCAATGGTTTTCATAGCTTCATCTATCAGGAAATAAAACTCTTACTAAAGAATAGCATACTGCATCTTTAAGCAGT
AGAGGGTAAACTACCTGCAAATGTGAATTTCTTAGATACATTTAAAAATATATAGTTGTTAACCTTCTGTGTGCCAAAAACTCTTAAGTT
ACATTTTCCTTCAAAGCAATGTACTTTTTTCTACATATGCAGTATGTAGTTAGCATAAAATCATTGGTGCCATGAAGATTATTTTTAAAC

>79609_79609_3_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000413748_FRMD5_chr15_44216507_ENST00000402883_length(amino acids)=647AA_BP=164
MTMVSRMVSTMLSGLLFWLASGWTPAFAYSPRTPDRVSEADIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPF
GNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPVGKTDDGCLENTPDTAEFSREFQLHQHLFDPEHDYPGLGKWRDAKGQYLFDLLCHHL
NLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAYI
LQAEIGDYDSGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFV
VLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYS
GRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSTSHGDTFLPHVRSSRT
DSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEVEALGGELRALCQGHSGPEEEQSGHLKGP

--------------------------------------------------------------
>79609_79609_4_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000413748_FRMD5_chr15_44216507_ENST00000417257_length(transcript)=5328nt_BP=596nt
TAAGATGCGGAGGAGGGTGACGCACTAGCTCTCCAGTTCGCCCGTTCCTGGCCTGACCCCCACCAAGGCCCATACCGCAGTAGGCTCCTC
GGGCTGCCCCTCGGTTGACAATGGTCTCCAGGATGGTCTCTACCATGCTATCTGGCCTACTGTTTTGGCTGGCATCTGGATGGACTCCAG
CATTTGCTTACAGCCCCCGGACCCCTGACCGGGTCTCAGAAGCAGATATCCAGAGGCTGCTTCATGGTGTTATGGAGCAATTGGGCATTG
CCAGGCCCCGAGTGGAATATCCAGCTCACCAGGCCATGAATCTTGTGGGCCCCCAGAGCATTGAAGGTGGAGCTCATGAAGGACTTCAGC
ATTTGGGTCCTTTTGGCAACATCCCCAACATCGTGGCAGAGTTGACTGGAGACAACATTCCTAAGGACTTTAGTGAGGATCAGGGGTACC
CAGACCCTCCAAATCCCTGTCCTGTTGGAAAAACAGATGATGGATGTCTAGAAAACACCCCTGACACTGCAGAGTTCAGTCGAGAGTTCC
AGTTGCACCAGCATCTCTTTGATCCGGAACATGACTATCCAGGCTTGGGCAAGTGGAGAGATGCCAAAGGCCAGTACCTGTTTGACCTTC
TTTGCCACCATCTGAACCTACTTGAGAAAGACTATTTTGGTATCCGCTTTGTAGACCCAGATAAGCAGCGGCATTGGCTGGAATTTACAA
AGTCTGTGGTGAAACAATTGAGATCCCAGCCTCCATTCACCATGTGCTTCCGTGTGAAGTTTTATCCTGCAGACCCTGCTGCTCTGAAAG
AAGAAATAACCAGGTATTTAGTCTTCCTGCAGATCAAAAGGGATCTCTACCATGGCCGACTCCTCTGTAAAACATCGGATGCTGCCTTGT
TAGCAGCTTACATCCTTCAAGCGGAGATTGGGGATTATGACTCAGGGAAACACCCTGAAGGCTACAGCTCCAAGTTCCAGTTTTTCCCTA
AACATTCAGAGAAGCTGGAAAGGAAAATTGCTGAGATTCACAAGACGGAACTGAGTGGTCAAACACCAGCAACATCAGAGCTGAACTTCT
TAAGAAAAGCACAGACATTGGAAACATATGGAGTGGATCCTCACCCATGTAAGGACGTGTCAGGAAATGCTGCATTTCTGGCCTTCACTC
CTTTTGGGTTTGTTGTTCTTCAAGGAAACAAGAGGGTCCACTTCATTAAATGGAATGAGGTGACCAAGCTGAAATTTGAAGGAAAGACTT
TCTATTTATACGTAAGTCAGAAAGAGGAAAAGAAAATTATTCTTACATATTTTGCTCCAACTCCTGAAGCGTGTAAGCACCTCTGGAAAT
GTGGAATCGAGAACCAAGCCTTCTACAAGCTGGAGAAGTCAAGCCAAGTCCGCACAGTGTCCAGCAGCAATTTATTCTTTAAAGGGAGCC
GGTTCCGATACAGTGGCCGAGTTGCAAAGGAAGTCATGGAATCAAGTGCTAAGATCAAACGGGAGCCACCGGAAATACACAGAGCAGGGA
TGGTTCCCAGCCGGAGCTGTCCCTCCATAACCCATGGCCCAAGGCTGAGCAGCGTCCCCAGGACCCGCAGAAGAGCTGTTCACATCTCCA
TCATGGAAGGCCTAGAGTCCTTACGGGACAGTGCCCATTCCACACCAGTGCGTTCCACTTCCCATGGGGACACCTTCCTGCCTCACGTGA
GAAGCAGCCGGACAGATAGCAATGAGCGAGTAGCTGTGATTGCAGACGAGGCCTACAGCCCTGCAGACAGCGTGCTGCCCACCCCTGTGG
CTGAGCACAGCCTGGAGCTGATGTTGCTTTCCCGGCAGATCAATGGAGCCACCTGCAGCATTGAGGAGGAGAAGGAATCTGAAGCCAGCA
CCCCAACTGCTACAGAGGTGGAGGCCCTTGGGGGAGAGCTGAGGGCCCTGTGTCAGGGGCACAGCGGGCCCGAGGAGGAACAGGTGAATA
AGTTTGTTCTAAGTGTCCTCCGTTTGCTCCTTGTGACCATGGGACTCCTCTTTGTTTTGCTCCTCCTCCTGATCATCCTTACCGAGTCTG
ACCTTGACATTGCCTTTTTCCGTGATATCCGCCAGACCCCCGAGTTTGAACAATTCCACTATCAATACTTTTGTCCCCTCAGGCGATGGT
TTGCCTGCAAAATCCGCTCAGTGGTGAGCCTGCTCATTGACACCTGAGAAGGCATGACTCCTCCCAAAAACTAGCCAGGTGGACCAAGGA
ACCCGGCTACCCATTCCCAGCAATGGGACCCATCGCGGAACCATCGGCACATATACCAAGTCCTCCTCTCATGACTCAAAGTCCACTGCA
GCCTAGGAGGGTGTTTCCCAGAAGAAGAAAGGGATAGGCTCATGCCCTGTCTAAACAAACTGGGAAAACTCATTTTCTTCAGAAGTTATT
TCAAGAAAGGCTCAGCGACTCTGTTTCTCATCTTTCCAATTTGCAGGATAATTTTTGGTTTTGAATTTTGATTTTTCATAGATGTATATT
ATTTTGAAGTATCAAATAAAAATAATTTATTTTACTATTACTGATTATTGCAGTAGTATCACCTAGCAGAGGGGACACTAGTTGAAAACT
AGAGAGCTGCTGTCCTCTGTATTCTGCAGGAGCTTTTCCTGCTGGTGCCACTGGGTTCCAGTAGACTCATCACTGCAGCCTCAGCAGGGC
AGGCCAGGGATCTGGACAATGGGGACTGTTTAGTTTTTTGTTTGTTTTTTTTGCCAGCCAGAACTTTTAAAAAAGTAAACATCCATGTAG
AATGATTAAATGGAAAGTTGCTTCTTATGATGGTCTGAGTTGGATTTTCTTTTCCTTTTGTTTTTTCAAATCTGAGCAGAGTGGGCATCT
GAAGGGACCACCGCTACAGCAACAGCAGCATCAGGGGTGGGGTAAGTCTGTCCCCTTAGTCTAGAGCCTAGTGGGCATCACCATAGTTTT
GTATAATGAAACTAGACTTAACGTGATTTTTTTTTTCCGAAGAACCTCAAGACTTTTATAGTGCTCCAGGGGCGTTAAACGAATTCAGTG
GTACCAGAGATAGATAGTTCTGTCAGAAATGTTGGACAAAGTGTAGTTAAGAGAAAGCAGAGTTAAGTTACCTGAGAGACTGTTGAGATT
TGGATAGCAGTGCTTATTTTATATACACCCCCTTGACCCAAAGACTATTTCAATTTATATTTTAACAACGAAATGTTATTTTCTTAACAA
TTCATATTTTGTTTTTACTTTATGGATTAAGAAAATAGAGCCTGATGAACTAAACGATGCAAGAAAGAAACTGATCCTGAGAATGAAAAG
CTTCAGAAAATAGAATTCCAAGATCAACAGCCTTAGAAGGGACCAGGAAAAGAATCTTTTAAAATAGATTTCTAAGAGATGCCTACAAAA
CACAGAATGTGACCGTGGCAGAGACCAACACTTAGATGTAGAAATGCTGCCCCCTAGGGTCATCCTCTGCATAAGTTCTAGGAAAGCATC
ACCATCCTTGCAGAGGGAAGTCCTCGAAGCACGCAGCACAGGCATATGAAGGGCGAGTGTGGGATCCTAGGCCCAAGCTCTTCAACTCTA
AAACCAATCACACACAAGATCCTGTTTTCATCTCAGGGAGAGATTTCTAAGTCATCTGGGGCTTGAGGGCTTATTTAAGGGTGGTCAATG
GACATATTCCTGGACCCACACAAAAGTAGAGCAGCTGCTGATACCCTAATTGGACAGCCCCAAACGCAGAACAGAACAAGTCACTTGTAG
ACTTGACCTCCCCTATTTTGTCCCCCGAGATGGTAGAACCATGTCCATGTTTACAATATGACAACTGTGGAATAATTGGGGTTCTTAGGG
AGAGATTTGCATAATTTTAAAGACATCCTTTCATCTGGACCAGAGGTCAATCAACTTATGTCAAGTGCTACACAGTAAATATTTTGGTTT
AGCACGCCATACTGTGTCACAACTGCTCAATTCTGCCATCACAGCACAAAAACAGCCACAGATAATTTGTAAATGAAGGAACATGGCTGT
GTTCCAATAAAACTTTATGAAAACAGTGAGCTGAATTTAGCCTACAGGCCATAATACGCCAATCCTGCTCTAGACAATAAAACTGATCCT
TACCAGTATGTTAGCAGAAGAGGGTCAGTCAGCTCTGTTTCCATGCCTGACATGTATCAAAGATCTGGGACCTCTTCCCAGTGGAGGCAC
TAGGGTTGCTTGTTTAAAGGGTGCTTGAACAACTAACCAGCAAAGAGATGTCTGATGCCAAATGGGCAAGATCAAATACTGGAATGCTAA
AACACAGCTGGAATCTAAGAAGGGAAGAGGGCTTCTCTGACCATTTTCATACCAGCAACAATTTAGGCAGAATTATAAACATCTATTTAT
CGAGTGACAATACAAACCGAAGGAGATCCTAGTAGAGATTAGGGGTCAGTTAAAATCAACTAGCCACTGCCACTTGTCATCTACATAGCA
AAGGCTTTATTTAGCACAGGACTAACGTGAAAAGTAGACCCAGAGATGAAAAGGCTGTCAGGAGACAGGGGGCTGGTGTCCACCTGGTAT
CTACTGTCTTATGCAACATAGAAGATTACCTTTTAGTGTAGTGCTCCTACCTCAGTTTGTAGAATCTGGTGTTTCTATGCAGTGAGTGAT
AGCCTCAACTCTGACCTTTCATATTCACATTAGAGACAGATGCAGTATTCCATATCCTAGTATGTTCCTTGTGTCTAGAGTTCTAACAGT
ACAGTAGTCTATGCCATTTCTAACAGCTAAATTTTGCTCTGTAAACAGAAACTTTAGGGTTGTTTTTTTCCAGGGCTCATCCCAGAAAAT
ATGGATAGAAAAGTTTCCTTCAGTTTGCTTTTCAAATAGTGCTTGAATAATAAACCTCCTTTGATTGGTGACTAGTCTTTTTTGGTATAT
CTCCACCTTTAAAAATTGTTCAAGTTTTTAACCTGGTTATACTGTGTTCTAACATGTCTCTCATTTTCTCTCAAAATTAGTTTATCTCAT
TGTAGAAAAAGCAATGGTTTTCATAGCTTCATCTATCAGGAAATAAAACTCTTACTAAAGAATAGCATACTGCATCTTTAAGCAGTAGAG
GGTAAACTACCTGCAAATGTGAATTTCTTAGATACATTTAAAAATATATAGTTGTTAACCTTCTGTGTGCCAAAAACTCTTAAGTTACAT
TTTCCTTCAAAGCAATGTACTTTTTTCTACATATGCAGTATGTAGTTAGCATAAAATCATTGGTGCCATGAAGATTATTTTTAAACTTAA

>79609_79609_4_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000413748_FRMD5_chr15_44216507_ENST00000417257_length(amino acids)=700AA_BP=164
MTMVSRMVSTMLSGLLFWLASGWTPAFAYSPRTPDRVSEADIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPF
GNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPVGKTDDGCLENTPDTAEFSREFQLHQHLFDPEHDYPGLGKWRDAKGQYLFDLLCHHL
NLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAYI
LQAEIGDYDSGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFV
VLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYS
GRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSTSHGDTFLPHVRSSRT
DSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEVEALGGELRALCQGHSGPEEEQVNKFVLS

--------------------------------------------------------------
>79609_79609_5_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000494364_FRMD5_chr15_44216507_ENST00000402883_length(transcript)=4406nt_BP=573nt
ACTAGCTCTCCAGTTCGCCCGTTCCTGGCCTGACCCCCACCAAGGCCCATACCGCAGTAGGCTCCTCGGGCTGCCCCTCGGTTGACAATG
GTCTCCAGGATGGTCTCTACCATGCTATCTGGCCTACTGTTTTGGCTGGCATCTGGATGGACTCCAGCATTTGCTTACAGCCCCCGGACC
CCTGACCGGGTCTCAGAAGCAGATATCCAGAGGCTGCTTCATGGTGTTATGGAGCAATTGGGCATTGCCAGGCCCCGAGTGGAATATCCA
GCTCACCAGGCCATGAATCTTGTGGGCCCCCAGAGCATTGAAGGTGGAGCTCATGAAGGACTTCAGCATTTGGGTCCTTTTGGCAACATC
CCCAACATCGTGGCAGAGTTGACTGGAGACAACATTCCTAAGGACTTTAGTGAGGATCAGGGGTACCCAGACCCTCCAAATCCCTGTCCT
GTTGGAAAAACAGATGATGGATGTCTAGAAAACACCCCTGACACTGCAGAGTTCAGTCGAGAGTTCCAGTTGCACCAGCATCTCTTTGAT
CCGGAACATGACTATCCAGGCTTGGGCAAGTGGAGAGATGCCAAAGGCCAGTACCTGTTTGACCTTCTTTGCCACCATCTGAACCTACTT
GAGAAAGACTATTTTGGTATCCGCTTTGTAGACCCAGATAAGCAGCGGCATTGGCTGGAATTTACAAAGTCTGTGGTGAAACAATTGAGA
TCCCAGCCTCCATTCACCATGTGCTTCCGTGTGAAGTTTTATCCTGCAGACCCTGCTGCTCTGAAAGAAGAAATAACCAGGTATTTAGTC
TTCCTGCAGATCAAAAGGGATCTCTACCATGGCCGACTCCTCTGTAAAACATCGGATGCTGCCTTGTTAGCAGCTTACATCCTTCAAGCG
GAGATTGGGGATTATGACTCAGGGAAACACCCTGAAGGCTACAGCTCCAAGTTCCAGTTTTTCCCTAAACATTCAGAGAAGCTGGAAAGG
AAAATTGCTGAGATTCACAAGACGGAACTGAGTGGTCAAACACCAGCAACATCAGAGCTGAACTTCTTAAGAAAAGCACAGACATTGGAA
ACATATGGAGTGGATCCTCACCCATGTAAGGACGTGTCAGGAAATGCTGCATTTCTGGCCTTCACTCCTTTTGGGTTTGTTGTTCTTCAA
GGAAACAAGAGGGTCCACTTCATTAAATGGAATGAGGTGACCAAGCTGAAATTTGAAGGAAAGACTTTCTATTTATACGTAAGTCAGAAA
GAGGAAAAGAAAATTATTCTTACATATTTTGCTCCAACTCCTGAAGCGTGTAAGCACCTCTGGAAATGTGGAATCGAGAACCAAGCCTTC
TACAAGCTGGAGAAGTCAAGCCAAGTCCGCACAGTGTCCAGCAGCAATTTATTCTTTAAAGGGAGCCGGTTCCGATACAGTGGCCGAGTT
GCAAAGGAAGTCATGGAATCAAGTGCTAAGATCAAACGGGAGCCACCGGAAATACACAGAGCAGGGATGGTTCCCAGCCGGAGCTGTCCC
TCCATAACCCATGGCCCAAGGCTGAGCAGCGTCCCCAGGACCCGCAGAAGAGCTGTTCACATCTCCATCATGGAAGGCCTAGAGTCCTTA
CGGGACAGTGCCCATTCCACACCAGTGCGTTCCACTTCCCATGGGGACACCTTCCTGCCTCACGTGAGAAGCAGCCGGACAGATAGCAAT
GAGCGAGTAGCTGTGATTGCAGACGAGGCCTACAGCCCTGCAGACAGCGTGCTGCCCACCCCTGTGGCTGAGCACAGCCTGGAGCTGATG
TTGCTTTCCCGGCAGATCAATGGAGCCACCTGCAGCATTGAGGAGGAGAAGGAATCTGAAGCCAGCACCCCAACTGCTACAGAGGTGGAG
GCCCTTGGGGGAGAGCTGAGGGCCCTGTGTCAGGGGCACAGCGGGCCCGAGGAGGAACAGAGTGGGCATCTGAAGGGACCACCGCTACAG
CAACAGCAGCATCAGGGGTGGGGTAAGTCTGTCCCCTTAGTCTAGAGCCTAGTGGGCATCACCATAGTTTTGTATAATGAAACTAGACTT
AACGTGATTTTTTTTTTCCGAAGAACCTCAAGACTTTTATAGTGCTCCAGGGGCGTTAAACGAATTCAGTGGTACCAGAGATAGATAGTT
CTGTCAGAAATGTTGGACAAAGTGTAGTTAAGAGAAAGCAGAGTTAAGTTACCTGAGAGACTGTTGAGATTTGGATAGCAGTGCTTATTT
TATATACACCCCCTTGACCCAAAGACTATTTCAATTTATATTTTAACAACGAAATGTTATTTTCTTAACAATTCATATTTTGTTTTTACT
TTATGGATTAAGAAAATAGAGCCTGATGAACTAAACGATGCAAGAAAGAAACTGATCCTGAGAATGAAAAGCTTCAGAAAATAGAATTCC
AAGATCAACAGCCTTAGAAGGGACCAGGAAAAGAATCTTTTAAAATAGATTTCTAAGAGATGCCTACAAAACACAGAATGTGACCGTGGC
AGAGACCAACACTTAGATGTAGAAATGCTGCCCCCTAGGGTCATCCTCTGCATAAGTTCTAGGAAAGCATCACCATCCTTGCAGAGGGAA
GTCCTCGAAGCACGCAGCACAGGCATATGAAGGGCGAGTGTGGGATCCTAGGCCCAAGCTCTTCAACTCTAAAACCAATCACACACAAGA
TCCTGTTTTCATCTCAGGGAGAGATTTCTAAGTCATCTGGGGCTTGAGGGCTTATTTAAGGGTGGTCAATGGACATATTCCTGGACCCAC
ACAAAAGTAGAGCAGCTGCTGATACCCTAATTGGACAGCCCCAAACGCAGAACAGAACAAGTCACTTGTAGACTTGACCTCCCCTATTTT
GTCCCCCGAGATGGTAGAACCATGTCCATGTTTACAATATGACAACTGTGGAATAATTGGGGTTCTTAGGGAGAGATTTGCATAATTTTA
AAGACATCCTTTCATCTGGACCAGAGGTCAATCAACTTATGTCAAGTGCTACACAGTAAATATTTTGGTTTAGCACGCCATACTGTGTCA
CAACTGCTCAATTCTGCCATCACAGCACAAAAACAGCCACAGATAATTTGTAAATGAAGGAACATGGCTGTGTTCCAATAAAACTTTATG
AAAACAGTGAGCTGAATTTAGCCTACAGGCCATAATACGCCAATCCTGCTCTAGACAATAAAACTGATCCTTACCAGTATGTTAGCAGAA
GAGGGTCAGTCAGCTCTGTTTCCATGCCTGACATGTATCAAAGATCTGGGACCTCTTCCCAGTGGAGGCACTAGGGTTGCTTGTTTAAAG
GGTGCTTGAACAACTAACCAGCAAAGAGATGTCTGATGCCAAATGGGCAAGATCAAATACTGGAATGCTAAAACACAGCTGGAATCTAAG
AAGGGAAGAGGGCTTCTCTGACCATTTTCATACCAGCAACAATTTAGGCAGAATTATAAACATCTATTTATCGAGTGACAATACAAACCG
AAGGAGATCCTAGTAGAGATTAGGGGTCAGTTAAAATCAACTAGCCACTGCCACTTGTCATCTACATAGCAAAGGCTTTATTTAGCACAG
GACTAACGTGAAAAGTAGACCCAGAGATGAAAAGGCTGTCAGGAGACAGGGGGCTGGTGTCCACCTGGTATCTACTGTCTTATGCAACAT
AGAAGATTACCTTTTAGTGTAGTGCTCCTACCTCAGTTTGTAGAATCTGGTGTTTCTATGCAGTGAGTGATAGCCTCAACTCTGACCTTT
CATATTCACATTAGAGACAGATGCAGTATTCCATATCCTAGTATGTTCCTTGTGTCTAGAGTTCTAACAGTACAGTAGTCTATGCCATTT
CTAACAGCTAAATTTTGCTCTGTAAACAGAAACTTTAGGGTTGTTTTTTTCCAGGGCTCATCCCAGAAAATATGGATAGAAAAGTTTCCT
TCAGTTTGCTTTTCAAATAGTGCTTGAATAATAAACCTCCTTTGATTGGTGACTAGTCTTTTTTGGTATATCTCCACCTTTAAAAATTGT
TCAAGTTTTTAACCTGGTTATACTGTGTTCTAACATGTCTCTCATTTTCTCTCAAAATTAGTTTATCTCATTGTAGAAAAAGCAATGGTT
TTCATAGCTTCATCTATCAGGAAATAAAACTCTTACTAAAGAATAGCATACTGCATCTTTAAGCAGTAGAGGGTAAACTACCTGCAAATG
TGAATTTCTTAGATACATTTAAAAATATATAGTTGTTAACCTTCTGTGTGCCAAAAACTCTTAAGTTACATTTTCCTTCAAAGCAATGTA

>79609_79609_5_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000494364_FRMD5_chr15_44216507_ENST00000402883_length(amino acids)=647AA_BP=164
MTMVSRMVSTMLSGLLFWLASGWTPAFAYSPRTPDRVSEADIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPF
GNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPVGKTDDGCLENTPDTAEFSREFQLHQHLFDPEHDYPGLGKWRDAKGQYLFDLLCHHL
NLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAYI
LQAEIGDYDSGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFV
VLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYS
GRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSTSHGDTFLPHVRSSRT
DSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEVEALGGELRALCQGHSGPEEEQSGHLKGP

--------------------------------------------------------------
>79609_79609_6_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000494364_FRMD5_chr15_44216507_ENST00000417257_length(transcript)=5305nt_BP=573nt
ACTAGCTCTCCAGTTCGCCCGTTCCTGGCCTGACCCCCACCAAGGCCCATACCGCAGTAGGCTCCTCGGGCTGCCCCTCGGTTGACAATG
GTCTCCAGGATGGTCTCTACCATGCTATCTGGCCTACTGTTTTGGCTGGCATCTGGATGGACTCCAGCATTTGCTTACAGCCCCCGGACC
CCTGACCGGGTCTCAGAAGCAGATATCCAGAGGCTGCTTCATGGTGTTATGGAGCAATTGGGCATTGCCAGGCCCCGAGTGGAATATCCA
GCTCACCAGGCCATGAATCTTGTGGGCCCCCAGAGCATTGAAGGTGGAGCTCATGAAGGACTTCAGCATTTGGGTCCTTTTGGCAACATC
CCCAACATCGTGGCAGAGTTGACTGGAGACAACATTCCTAAGGACTTTAGTGAGGATCAGGGGTACCCAGACCCTCCAAATCCCTGTCCT
GTTGGAAAAACAGATGATGGATGTCTAGAAAACACCCCTGACACTGCAGAGTTCAGTCGAGAGTTCCAGTTGCACCAGCATCTCTTTGAT
CCGGAACATGACTATCCAGGCTTGGGCAAGTGGAGAGATGCCAAAGGCCAGTACCTGTTTGACCTTCTTTGCCACCATCTGAACCTACTT
GAGAAAGACTATTTTGGTATCCGCTTTGTAGACCCAGATAAGCAGCGGCATTGGCTGGAATTTACAAAGTCTGTGGTGAAACAATTGAGA
TCCCAGCCTCCATTCACCATGTGCTTCCGTGTGAAGTTTTATCCTGCAGACCCTGCTGCTCTGAAAGAAGAAATAACCAGGTATTTAGTC
TTCCTGCAGATCAAAAGGGATCTCTACCATGGCCGACTCCTCTGTAAAACATCGGATGCTGCCTTGTTAGCAGCTTACATCCTTCAAGCG
GAGATTGGGGATTATGACTCAGGGAAACACCCTGAAGGCTACAGCTCCAAGTTCCAGTTTTTCCCTAAACATTCAGAGAAGCTGGAAAGG
AAAATTGCTGAGATTCACAAGACGGAACTGAGTGGTCAAACACCAGCAACATCAGAGCTGAACTTCTTAAGAAAAGCACAGACATTGGAA
ACATATGGAGTGGATCCTCACCCATGTAAGGACGTGTCAGGAAATGCTGCATTTCTGGCCTTCACTCCTTTTGGGTTTGTTGTTCTTCAA
GGAAACAAGAGGGTCCACTTCATTAAATGGAATGAGGTGACCAAGCTGAAATTTGAAGGAAAGACTTTCTATTTATACGTAAGTCAGAAA
GAGGAAAAGAAAATTATTCTTACATATTTTGCTCCAACTCCTGAAGCGTGTAAGCACCTCTGGAAATGTGGAATCGAGAACCAAGCCTTC
TACAAGCTGGAGAAGTCAAGCCAAGTCCGCACAGTGTCCAGCAGCAATTTATTCTTTAAAGGGAGCCGGTTCCGATACAGTGGCCGAGTT
GCAAAGGAAGTCATGGAATCAAGTGCTAAGATCAAACGGGAGCCACCGGAAATACACAGAGCAGGGATGGTTCCCAGCCGGAGCTGTCCC
TCCATAACCCATGGCCCAAGGCTGAGCAGCGTCCCCAGGACCCGCAGAAGAGCTGTTCACATCTCCATCATGGAAGGCCTAGAGTCCTTA
CGGGACAGTGCCCATTCCACACCAGTGCGTTCCACTTCCCATGGGGACACCTTCCTGCCTCACGTGAGAAGCAGCCGGACAGATAGCAAT
GAGCGAGTAGCTGTGATTGCAGACGAGGCCTACAGCCCTGCAGACAGCGTGCTGCCCACCCCTGTGGCTGAGCACAGCCTGGAGCTGATG
TTGCTTTCCCGGCAGATCAATGGAGCCACCTGCAGCATTGAGGAGGAGAAGGAATCTGAAGCCAGCACCCCAACTGCTACAGAGGTGGAG
GCCCTTGGGGGAGAGCTGAGGGCCCTGTGTCAGGGGCACAGCGGGCCCGAGGAGGAACAGGTGAATAAGTTTGTTCTAAGTGTCCTCCGT
TTGCTCCTTGTGACCATGGGACTCCTCTTTGTTTTGCTCCTCCTCCTGATCATCCTTACCGAGTCTGACCTTGACATTGCCTTTTTCCGT
GATATCCGCCAGACCCCCGAGTTTGAACAATTCCACTATCAATACTTTTGTCCCCTCAGGCGATGGTTTGCCTGCAAAATCCGCTCAGTG
GTGAGCCTGCTCATTGACACCTGAGAAGGCATGACTCCTCCCAAAAACTAGCCAGGTGGACCAAGGAACCCGGCTACCCATTCCCAGCAA
TGGGACCCATCGCGGAACCATCGGCACATATACCAAGTCCTCCTCTCATGACTCAAAGTCCACTGCAGCCTAGGAGGGTGTTTCCCAGAA
GAAGAAAGGGATAGGCTCATGCCCTGTCTAAACAAACTGGGAAAACTCATTTTCTTCAGAAGTTATTTCAAGAAAGGCTCAGCGACTCTG
TTTCTCATCTTTCCAATTTGCAGGATAATTTTTGGTTTTGAATTTTGATTTTTCATAGATGTATATTATTTTGAAGTATCAAATAAAAAT
AATTTATTTTACTATTACTGATTATTGCAGTAGTATCACCTAGCAGAGGGGACACTAGTTGAAAACTAGAGAGCTGCTGTCCTCTGTATT
CTGCAGGAGCTTTTCCTGCTGGTGCCACTGGGTTCCAGTAGACTCATCACTGCAGCCTCAGCAGGGCAGGCCAGGGATCTGGACAATGGG
GACTGTTTAGTTTTTTGTTTGTTTTTTTTGCCAGCCAGAACTTTTAAAAAAGTAAACATCCATGTAGAATGATTAAATGGAAAGTTGCTT
CTTATGATGGTCTGAGTTGGATTTTCTTTTCCTTTTGTTTTTTCAAATCTGAGCAGAGTGGGCATCTGAAGGGACCACCGCTACAGCAAC
AGCAGCATCAGGGGTGGGGTAAGTCTGTCCCCTTAGTCTAGAGCCTAGTGGGCATCACCATAGTTTTGTATAATGAAACTAGACTTAACG
TGATTTTTTTTTTCCGAAGAACCTCAAGACTTTTATAGTGCTCCAGGGGCGTTAAACGAATTCAGTGGTACCAGAGATAGATAGTTCTGT
CAGAAATGTTGGACAAAGTGTAGTTAAGAGAAAGCAGAGTTAAGTTACCTGAGAGACTGTTGAGATTTGGATAGCAGTGCTTATTTTATA
TACACCCCCTTGACCCAAAGACTATTTCAATTTATATTTTAACAACGAAATGTTATTTTCTTAACAATTCATATTTTGTTTTTACTTTAT
GGATTAAGAAAATAGAGCCTGATGAACTAAACGATGCAAGAAAGAAACTGATCCTGAGAATGAAAAGCTTCAGAAAATAGAATTCCAAGA
TCAACAGCCTTAGAAGGGACCAGGAAAAGAATCTTTTAAAATAGATTTCTAAGAGATGCCTACAAAACACAGAATGTGACCGTGGCAGAG
ACCAACACTTAGATGTAGAAATGCTGCCCCCTAGGGTCATCCTCTGCATAAGTTCTAGGAAAGCATCACCATCCTTGCAGAGGGAAGTCC
TCGAAGCACGCAGCACAGGCATATGAAGGGCGAGTGTGGGATCCTAGGCCCAAGCTCTTCAACTCTAAAACCAATCACACACAAGATCCT
GTTTTCATCTCAGGGAGAGATTTCTAAGTCATCTGGGGCTTGAGGGCTTATTTAAGGGTGGTCAATGGACATATTCCTGGACCCACACAA
AAGTAGAGCAGCTGCTGATACCCTAATTGGACAGCCCCAAACGCAGAACAGAACAAGTCACTTGTAGACTTGACCTCCCCTATTTTGTCC
CCCGAGATGGTAGAACCATGTCCATGTTTACAATATGACAACTGTGGAATAATTGGGGTTCTTAGGGAGAGATTTGCATAATTTTAAAGA
CATCCTTTCATCTGGACCAGAGGTCAATCAACTTATGTCAAGTGCTACACAGTAAATATTTTGGTTTAGCACGCCATACTGTGTCACAAC
TGCTCAATTCTGCCATCACAGCACAAAAACAGCCACAGATAATTTGTAAATGAAGGAACATGGCTGTGTTCCAATAAAACTTTATGAAAA
CAGTGAGCTGAATTTAGCCTACAGGCCATAATACGCCAATCCTGCTCTAGACAATAAAACTGATCCTTACCAGTATGTTAGCAGAAGAGG
GTCAGTCAGCTCTGTTTCCATGCCTGACATGTATCAAAGATCTGGGACCTCTTCCCAGTGGAGGCACTAGGGTTGCTTGTTTAAAGGGTG
CTTGAACAACTAACCAGCAAAGAGATGTCTGATGCCAAATGGGCAAGATCAAATACTGGAATGCTAAAACACAGCTGGAATCTAAGAAGG
GAAGAGGGCTTCTCTGACCATTTTCATACCAGCAACAATTTAGGCAGAATTATAAACATCTATTTATCGAGTGACAATACAAACCGAAGG
AGATCCTAGTAGAGATTAGGGGTCAGTTAAAATCAACTAGCCACTGCCACTTGTCATCTACATAGCAAAGGCTTTATTTAGCACAGGACT
AACGTGAAAAGTAGACCCAGAGATGAAAAGGCTGTCAGGAGACAGGGGGCTGGTGTCCACCTGGTATCTACTGTCTTATGCAACATAGAA
GATTACCTTTTAGTGTAGTGCTCCTACCTCAGTTTGTAGAATCTGGTGTTTCTATGCAGTGAGTGATAGCCTCAACTCTGACCTTTCATA
TTCACATTAGAGACAGATGCAGTATTCCATATCCTAGTATGTTCCTTGTGTCTAGAGTTCTAACAGTACAGTAGTCTATGCCATTTCTAA
CAGCTAAATTTTGCTCTGTAAACAGAAACTTTAGGGTTGTTTTTTTCCAGGGCTCATCCCAGAAAATATGGATAGAAAAGTTTCCTTCAG
TTTGCTTTTCAAATAGTGCTTGAATAATAAACCTCCTTTGATTGGTGACTAGTCTTTTTTGGTATATCTCCACCTTTAAAAATTGTTCAA
GTTTTTAACCTGGTTATACTGTGTTCTAACATGTCTCTCATTTTCTCTCAAAATTAGTTTATCTCATTGTAGAAAAAGCAATGGTTTTCA
TAGCTTCATCTATCAGGAAATAAAACTCTTACTAAAGAATAGCATACTGCATCTTTAAGCAGTAGAGGGTAAACTACCTGCAAATGTGAA
TTTCTTAGATACATTTAAAAATATATAGTTGTTAACCTTCTGTGTGCCAAAAACTCTTAAGTTACATTTTCCTTCAAAGCAATGTACTTT

>79609_79609_6_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000494364_FRMD5_chr15_44216507_ENST00000417257_length(amino acids)=700AA_BP=164
MTMVSRMVSTMLSGLLFWLASGWTPAFAYSPRTPDRVSEADIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPF
GNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPVGKTDDGCLENTPDTAEFSREFQLHQHLFDPEHDYPGLGKWRDAKGQYLFDLLCHHL
NLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAYI
LQAEIGDYDSGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFV
VLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYS
GRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSTSHGDTFLPHVRSSRT
DSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEVEALGGELRALCQGHSGPEEEQVNKFVLS

--------------------------------------------------------------
>79609_79609_7_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000497208_FRMD5_chr15_44216507_ENST00000402883_length(transcript)=4406nt_BP=573nt
AGCTCTCCAGTTCGCCCGTTCCTGGCCTGACCCCCACCAAGGCCCATACCGCAGTAGGCTCCTCGGGCTGCCCCTCGGTTGACAATGGTC
TCCAGGATGGTCTCTACCATGCTATCTGGCCTACTGTTTTGGCTGGCATCTGGATGGACTCCAGCATTTGCTTACAGCCCCCGGACCCCT
GACCGGGTCTCAGAAGCAGATATCCAGAGGCTGCTTCATGGTGTTATGGAGCAATTGGGCATTGCCAGGCCCCGAGTGGAATATCCAGCT
CACCAGGCCATGAATCTTGTGGGCCCCCAGAGCATTGAAGGTGGAGCTCATGAAGGACTTCAGCATTTGGGTCCTTTTGGCAACATCCCC
AACATCGTGGCAGAGTTGACTGGAGACAACATTCCTAAGGACTTTAGTGAGGATCAGGGGTACCCAGACCCTCCAAATCCCTGTCCTGTT
GGAAAAACAGCAGATGATGGATGTCTAGAAAACACCCCTGACACTGCAGAGTTCAGTCGAGAGTTCCAGTTGCACCAGCATCTCTTTGAT
CCGGAACATGACTATCCAGGCTTGGGCAAGTGGAGAGATGCCAAAGGCCAGTACCTGTTTGACCTTCTTTGCCACCATCTGAACCTACTT
GAGAAAGACTATTTTGGTATCCGCTTTGTAGACCCAGATAAGCAGCGGCATTGGCTGGAATTTACAAAGTCTGTGGTGAAACAATTGAGA
TCCCAGCCTCCATTCACCATGTGCTTCCGTGTGAAGTTTTATCCTGCAGACCCTGCTGCTCTGAAAGAAGAAATAACCAGGTATTTAGTC
TTCCTGCAGATCAAAAGGGATCTCTACCATGGCCGACTCCTCTGTAAAACATCGGATGCTGCCTTGTTAGCAGCTTACATCCTTCAAGCG
GAGATTGGGGATTATGACTCAGGGAAACACCCTGAAGGCTACAGCTCCAAGTTCCAGTTTTTCCCTAAACATTCAGAGAAGCTGGAAAGG
AAAATTGCTGAGATTCACAAGACGGAACTGAGTGGTCAAACACCAGCAACATCAGAGCTGAACTTCTTAAGAAAAGCACAGACATTGGAA
ACATATGGAGTGGATCCTCACCCATGTAAGGACGTGTCAGGAAATGCTGCATTTCTGGCCTTCACTCCTTTTGGGTTTGTTGTTCTTCAA
GGAAACAAGAGGGTCCACTTCATTAAATGGAATGAGGTGACCAAGCTGAAATTTGAAGGAAAGACTTTCTATTTATACGTAAGTCAGAAA
GAGGAAAAGAAAATTATTCTTACATATTTTGCTCCAACTCCTGAAGCGTGTAAGCACCTCTGGAAATGTGGAATCGAGAACCAAGCCTTC
TACAAGCTGGAGAAGTCAAGCCAAGTCCGCACAGTGTCCAGCAGCAATTTATTCTTTAAAGGGAGCCGGTTCCGATACAGTGGCCGAGTT
GCAAAGGAAGTCATGGAATCAAGTGCTAAGATCAAACGGGAGCCACCGGAAATACACAGAGCAGGGATGGTTCCCAGCCGGAGCTGTCCC
TCCATAACCCATGGCCCAAGGCTGAGCAGCGTCCCCAGGACCCGCAGAAGAGCTGTTCACATCTCCATCATGGAAGGCCTAGAGTCCTTA
CGGGACAGTGCCCATTCCACACCAGTGCGTTCCACTTCCCATGGGGACACCTTCCTGCCTCACGTGAGAAGCAGCCGGACAGATAGCAAT
GAGCGAGTAGCTGTGATTGCAGACGAGGCCTACAGCCCTGCAGACAGCGTGCTGCCCACCCCTGTGGCTGAGCACAGCCTGGAGCTGATG
TTGCTTTCCCGGCAGATCAATGGAGCCACCTGCAGCATTGAGGAGGAGAAGGAATCTGAAGCCAGCACCCCAACTGCTACAGAGGTGGAG
GCCCTTGGGGGAGAGCTGAGGGCCCTGTGTCAGGGGCACAGCGGGCCCGAGGAGGAACAGAGTGGGCATCTGAAGGGACCACCGCTACAG
CAACAGCAGCATCAGGGGTGGGGTAAGTCTGTCCCCTTAGTCTAGAGCCTAGTGGGCATCACCATAGTTTTGTATAATGAAACTAGACTT
AACGTGATTTTTTTTTTCCGAAGAACCTCAAGACTTTTATAGTGCTCCAGGGGCGTTAAACGAATTCAGTGGTACCAGAGATAGATAGTT
CTGTCAGAAATGTTGGACAAAGTGTAGTTAAGAGAAAGCAGAGTTAAGTTACCTGAGAGACTGTTGAGATTTGGATAGCAGTGCTTATTT
TATATACACCCCCTTGACCCAAAGACTATTTCAATTTATATTTTAACAACGAAATGTTATTTTCTTAACAATTCATATTTTGTTTTTACT
TTATGGATTAAGAAAATAGAGCCTGATGAACTAAACGATGCAAGAAAGAAACTGATCCTGAGAATGAAAAGCTTCAGAAAATAGAATTCC
AAGATCAACAGCCTTAGAAGGGACCAGGAAAAGAATCTTTTAAAATAGATTTCTAAGAGATGCCTACAAAACACAGAATGTGACCGTGGC
AGAGACCAACACTTAGATGTAGAAATGCTGCCCCCTAGGGTCATCCTCTGCATAAGTTCTAGGAAAGCATCACCATCCTTGCAGAGGGAA
GTCCTCGAAGCACGCAGCACAGGCATATGAAGGGCGAGTGTGGGATCCTAGGCCCAAGCTCTTCAACTCTAAAACCAATCACACACAAGA
TCCTGTTTTCATCTCAGGGAGAGATTTCTAAGTCATCTGGGGCTTGAGGGCTTATTTAAGGGTGGTCAATGGACATATTCCTGGACCCAC
ACAAAAGTAGAGCAGCTGCTGATACCCTAATTGGACAGCCCCAAACGCAGAACAGAACAAGTCACTTGTAGACTTGACCTCCCCTATTTT
GTCCCCCGAGATGGTAGAACCATGTCCATGTTTACAATATGACAACTGTGGAATAATTGGGGTTCTTAGGGAGAGATTTGCATAATTTTA
AAGACATCCTTTCATCTGGACCAGAGGTCAATCAACTTATGTCAAGTGCTACACAGTAAATATTTTGGTTTAGCACGCCATACTGTGTCA
CAACTGCTCAATTCTGCCATCACAGCACAAAAACAGCCACAGATAATTTGTAAATGAAGGAACATGGCTGTGTTCCAATAAAACTTTATG
AAAACAGTGAGCTGAATTTAGCCTACAGGCCATAATACGCCAATCCTGCTCTAGACAATAAAACTGATCCTTACCAGTATGTTAGCAGAA
GAGGGTCAGTCAGCTCTGTTTCCATGCCTGACATGTATCAAAGATCTGGGACCTCTTCCCAGTGGAGGCACTAGGGTTGCTTGTTTAAAG
GGTGCTTGAACAACTAACCAGCAAAGAGATGTCTGATGCCAAATGGGCAAGATCAAATACTGGAATGCTAAAACACAGCTGGAATCTAAG
AAGGGAAGAGGGCTTCTCTGACCATTTTCATACCAGCAACAATTTAGGCAGAATTATAAACATCTATTTATCGAGTGACAATACAAACCG
AAGGAGATCCTAGTAGAGATTAGGGGTCAGTTAAAATCAACTAGCCACTGCCACTTGTCATCTACATAGCAAAGGCTTTATTTAGCACAG
GACTAACGTGAAAAGTAGACCCAGAGATGAAAAGGCTGTCAGGAGACAGGGGGCTGGTGTCCACCTGGTATCTACTGTCTTATGCAACAT
AGAAGATTACCTTTTAGTGTAGTGCTCCTACCTCAGTTTGTAGAATCTGGTGTTTCTATGCAGTGAGTGATAGCCTCAACTCTGACCTTT
CATATTCACATTAGAGACAGATGCAGTATTCCATATCCTAGTATGTTCCTTGTGTCTAGAGTTCTAACAGTACAGTAGTCTATGCCATTT
CTAACAGCTAAATTTTGCTCTGTAAACAGAAACTTTAGGGTTGTTTTTTTCCAGGGCTCATCCCAGAAAATATGGATAGAAAAGTTTCCT
TCAGTTTGCTTTTCAAATAGTGCTTGAATAATAAACCTCCTTTGATTGGTGACTAGTCTTTTTTGGTATATCTCCACCTTTAAAAATTGT
TCAAGTTTTTAACCTGGTTATACTGTGTTCTAACATGTCTCTCATTTTCTCTCAAAATTAGTTTATCTCATTGTAGAAAAAGCAATGGTT
TTCATAGCTTCATCTATCAGGAAATAAAACTCTTACTAAAGAATAGCATACTGCATCTTTAAGCAGTAGAGGGTAAACTACCTGCAAATG
TGAATTTCTTAGATACATTTAAAAATATATAGTTGTTAACCTTCTGTGTGCCAAAAACTCTTAAGTTACATTTTCCTTCAAAGCAATGTA

>79609_79609_7_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000497208_FRMD5_chr15_44216507_ENST00000402883_length(amino acids)=648AA_BP=165
MTMVSRMVSTMLSGLLFWLASGWTPAFAYSPRTPDRVSEADIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPF
GNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPVGKTADDGCLENTPDTAEFSREFQLHQHLFDPEHDYPGLGKWRDAKGQYLFDLLCHH
LNLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAY
ILQAEIGDYDSGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGF
VVLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRY
SGRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSTSHGDTFLPHVRSSR
TDSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEVEALGGELRALCQGHSGPEEEQSGHLKG

--------------------------------------------------------------
>79609_79609_8_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000497208_FRMD5_chr15_44216507_ENST00000417257_length(transcript)=5305nt_BP=573nt
AGCTCTCCAGTTCGCCCGTTCCTGGCCTGACCCCCACCAAGGCCCATACCGCAGTAGGCTCCTCGGGCTGCCCCTCGGTTGACAATGGTC
TCCAGGATGGTCTCTACCATGCTATCTGGCCTACTGTTTTGGCTGGCATCTGGATGGACTCCAGCATTTGCTTACAGCCCCCGGACCCCT
GACCGGGTCTCAGAAGCAGATATCCAGAGGCTGCTTCATGGTGTTATGGAGCAATTGGGCATTGCCAGGCCCCGAGTGGAATATCCAGCT
CACCAGGCCATGAATCTTGTGGGCCCCCAGAGCATTGAAGGTGGAGCTCATGAAGGACTTCAGCATTTGGGTCCTTTTGGCAACATCCCC
AACATCGTGGCAGAGTTGACTGGAGACAACATTCCTAAGGACTTTAGTGAGGATCAGGGGTACCCAGACCCTCCAAATCCCTGTCCTGTT
GGAAAAACAGCAGATGATGGATGTCTAGAAAACACCCCTGACACTGCAGAGTTCAGTCGAGAGTTCCAGTTGCACCAGCATCTCTTTGAT
CCGGAACATGACTATCCAGGCTTGGGCAAGTGGAGAGATGCCAAAGGCCAGTACCTGTTTGACCTTCTTTGCCACCATCTGAACCTACTT
GAGAAAGACTATTTTGGTATCCGCTTTGTAGACCCAGATAAGCAGCGGCATTGGCTGGAATTTACAAAGTCTGTGGTGAAACAATTGAGA
TCCCAGCCTCCATTCACCATGTGCTTCCGTGTGAAGTTTTATCCTGCAGACCCTGCTGCTCTGAAAGAAGAAATAACCAGGTATTTAGTC
TTCCTGCAGATCAAAAGGGATCTCTACCATGGCCGACTCCTCTGTAAAACATCGGATGCTGCCTTGTTAGCAGCTTACATCCTTCAAGCG
GAGATTGGGGATTATGACTCAGGGAAACACCCTGAAGGCTACAGCTCCAAGTTCCAGTTTTTCCCTAAACATTCAGAGAAGCTGGAAAGG
AAAATTGCTGAGATTCACAAGACGGAACTGAGTGGTCAAACACCAGCAACATCAGAGCTGAACTTCTTAAGAAAAGCACAGACATTGGAA
ACATATGGAGTGGATCCTCACCCATGTAAGGACGTGTCAGGAAATGCTGCATTTCTGGCCTTCACTCCTTTTGGGTTTGTTGTTCTTCAA
GGAAACAAGAGGGTCCACTTCATTAAATGGAATGAGGTGACCAAGCTGAAATTTGAAGGAAAGACTTTCTATTTATACGTAAGTCAGAAA
GAGGAAAAGAAAATTATTCTTACATATTTTGCTCCAACTCCTGAAGCGTGTAAGCACCTCTGGAAATGTGGAATCGAGAACCAAGCCTTC
TACAAGCTGGAGAAGTCAAGCCAAGTCCGCACAGTGTCCAGCAGCAATTTATTCTTTAAAGGGAGCCGGTTCCGATACAGTGGCCGAGTT
GCAAAGGAAGTCATGGAATCAAGTGCTAAGATCAAACGGGAGCCACCGGAAATACACAGAGCAGGGATGGTTCCCAGCCGGAGCTGTCCC
TCCATAACCCATGGCCCAAGGCTGAGCAGCGTCCCCAGGACCCGCAGAAGAGCTGTTCACATCTCCATCATGGAAGGCCTAGAGTCCTTA
CGGGACAGTGCCCATTCCACACCAGTGCGTTCCACTTCCCATGGGGACACCTTCCTGCCTCACGTGAGAAGCAGCCGGACAGATAGCAAT
GAGCGAGTAGCTGTGATTGCAGACGAGGCCTACAGCCCTGCAGACAGCGTGCTGCCCACCCCTGTGGCTGAGCACAGCCTGGAGCTGATG
TTGCTTTCCCGGCAGATCAATGGAGCCACCTGCAGCATTGAGGAGGAGAAGGAATCTGAAGCCAGCACCCCAACTGCTACAGAGGTGGAG
GCCCTTGGGGGAGAGCTGAGGGCCCTGTGTCAGGGGCACAGCGGGCCCGAGGAGGAACAGGTGAATAAGTTTGTTCTAAGTGTCCTCCGT
TTGCTCCTTGTGACCATGGGACTCCTCTTTGTTTTGCTCCTCCTCCTGATCATCCTTACCGAGTCTGACCTTGACATTGCCTTTTTCCGT
GATATCCGCCAGACCCCCGAGTTTGAACAATTCCACTATCAATACTTTTGTCCCCTCAGGCGATGGTTTGCCTGCAAAATCCGCTCAGTG
GTGAGCCTGCTCATTGACACCTGAGAAGGCATGACTCCTCCCAAAAACTAGCCAGGTGGACCAAGGAACCCGGCTACCCATTCCCAGCAA
TGGGACCCATCGCGGAACCATCGGCACATATACCAAGTCCTCCTCTCATGACTCAAAGTCCACTGCAGCCTAGGAGGGTGTTTCCCAGAA
GAAGAAAGGGATAGGCTCATGCCCTGTCTAAACAAACTGGGAAAACTCATTTTCTTCAGAAGTTATTTCAAGAAAGGCTCAGCGACTCTG
TTTCTCATCTTTCCAATTTGCAGGATAATTTTTGGTTTTGAATTTTGATTTTTCATAGATGTATATTATTTTGAAGTATCAAATAAAAAT
AATTTATTTTACTATTACTGATTATTGCAGTAGTATCACCTAGCAGAGGGGACACTAGTTGAAAACTAGAGAGCTGCTGTCCTCTGTATT
CTGCAGGAGCTTTTCCTGCTGGTGCCACTGGGTTCCAGTAGACTCATCACTGCAGCCTCAGCAGGGCAGGCCAGGGATCTGGACAATGGG
GACTGTTTAGTTTTTTGTTTGTTTTTTTTGCCAGCCAGAACTTTTAAAAAAGTAAACATCCATGTAGAATGATTAAATGGAAAGTTGCTT
CTTATGATGGTCTGAGTTGGATTTTCTTTTCCTTTTGTTTTTTCAAATCTGAGCAGAGTGGGCATCTGAAGGGACCACCGCTACAGCAAC
AGCAGCATCAGGGGTGGGGTAAGTCTGTCCCCTTAGTCTAGAGCCTAGTGGGCATCACCATAGTTTTGTATAATGAAACTAGACTTAACG
TGATTTTTTTTTTCCGAAGAACCTCAAGACTTTTATAGTGCTCCAGGGGCGTTAAACGAATTCAGTGGTACCAGAGATAGATAGTTCTGT
CAGAAATGTTGGACAAAGTGTAGTTAAGAGAAAGCAGAGTTAAGTTACCTGAGAGACTGTTGAGATTTGGATAGCAGTGCTTATTTTATA
TACACCCCCTTGACCCAAAGACTATTTCAATTTATATTTTAACAACGAAATGTTATTTTCTTAACAATTCATATTTTGTTTTTACTTTAT
GGATTAAGAAAATAGAGCCTGATGAACTAAACGATGCAAGAAAGAAACTGATCCTGAGAATGAAAAGCTTCAGAAAATAGAATTCCAAGA
TCAACAGCCTTAGAAGGGACCAGGAAAAGAATCTTTTAAAATAGATTTCTAAGAGATGCCTACAAAACACAGAATGTGACCGTGGCAGAG
ACCAACACTTAGATGTAGAAATGCTGCCCCCTAGGGTCATCCTCTGCATAAGTTCTAGGAAAGCATCACCATCCTTGCAGAGGGAAGTCC
TCGAAGCACGCAGCACAGGCATATGAAGGGCGAGTGTGGGATCCTAGGCCCAAGCTCTTCAACTCTAAAACCAATCACACACAAGATCCT
GTTTTCATCTCAGGGAGAGATTTCTAAGTCATCTGGGGCTTGAGGGCTTATTTAAGGGTGGTCAATGGACATATTCCTGGACCCACACAA
AAGTAGAGCAGCTGCTGATACCCTAATTGGACAGCCCCAAACGCAGAACAGAACAAGTCACTTGTAGACTTGACCTCCCCTATTTTGTCC
CCCGAGATGGTAGAACCATGTCCATGTTTACAATATGACAACTGTGGAATAATTGGGGTTCTTAGGGAGAGATTTGCATAATTTTAAAGA
CATCCTTTCATCTGGACCAGAGGTCAATCAACTTATGTCAAGTGCTACACAGTAAATATTTTGGTTTAGCACGCCATACTGTGTCACAAC
TGCTCAATTCTGCCATCACAGCACAAAAACAGCCACAGATAATTTGTAAATGAAGGAACATGGCTGTGTTCCAATAAAACTTTATGAAAA
CAGTGAGCTGAATTTAGCCTACAGGCCATAATACGCCAATCCTGCTCTAGACAATAAAACTGATCCTTACCAGTATGTTAGCAGAAGAGG
GTCAGTCAGCTCTGTTTCCATGCCTGACATGTATCAAAGATCTGGGACCTCTTCCCAGTGGAGGCACTAGGGTTGCTTGTTTAAAGGGTG
CTTGAACAACTAACCAGCAAAGAGATGTCTGATGCCAAATGGGCAAGATCAAATACTGGAATGCTAAAACACAGCTGGAATCTAAGAAGG
GAAGAGGGCTTCTCTGACCATTTTCATACCAGCAACAATTTAGGCAGAATTATAAACATCTATTTATCGAGTGACAATACAAACCGAAGG
AGATCCTAGTAGAGATTAGGGGTCAGTTAAAATCAACTAGCCACTGCCACTTGTCATCTACATAGCAAAGGCTTTATTTAGCACAGGACT
AACGTGAAAAGTAGACCCAGAGATGAAAAGGCTGTCAGGAGACAGGGGGCTGGTGTCCACCTGGTATCTACTGTCTTATGCAACATAGAA
GATTACCTTTTAGTGTAGTGCTCCTACCTCAGTTTGTAGAATCTGGTGTTTCTATGCAGTGAGTGATAGCCTCAACTCTGACCTTTCATA
TTCACATTAGAGACAGATGCAGTATTCCATATCCTAGTATGTTCCTTGTGTCTAGAGTTCTAACAGTACAGTAGTCTATGCCATTTCTAA
CAGCTAAATTTTGCTCTGTAAACAGAAACTTTAGGGTTGTTTTTTTCCAGGGCTCATCCCAGAAAATATGGATAGAAAAGTTTCCTTCAG
TTTGCTTTTCAAATAGTGCTTGAATAATAAACCTCCTTTGATTGGTGACTAGTCTTTTTTGGTATATCTCCACCTTTAAAAATTGTTCAA
GTTTTTAACCTGGTTATACTGTGTTCTAACATGTCTCTCATTTTCTCTCAAAATTAGTTTATCTCATTGTAGAAAAAGCAATGGTTTTCA
TAGCTTCATCTATCAGGAAATAAAACTCTTACTAAAGAATAGCATACTGCATCTTTAAGCAGTAGAGGGTAAACTACCTGCAAATGTGAA
TTTCTTAGATACATTTAAAAATATATAGTTGTTAACCTTCTGTGTGCCAAAAACTCTTAAGTTACATTTTCCTTCAAAGCAATGTACTTT

>79609_79609_8_SCG5-FRMD5_SCG5_chr15_32976870_ENST00000497208_FRMD5_chr15_44216507_ENST00000417257_length(amino acids)=701AA_BP=165
MTMVSRMVSTMLSGLLFWLASGWTPAFAYSPRTPDRVSEADIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPF
GNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPVGKTADDGCLENTPDTAEFSREFQLHQHLFDPEHDYPGLGKWRDAKGQYLFDLLCHH
LNLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAY
ILQAEIGDYDSGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGF
VVLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRY
SGRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSTSHGDTFLPHVRSSR
TDSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEVEALGGELRALCQGHSGPEEEQVNKFVL

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Fusion Gene PPI Analysis for SCG5-FRMD5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneFRMD5chr15:32976870chr15:44216507ENST00000417257014308_35334.0571.0ROCK1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SCG5-FRMD5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SCG5-FRMD5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource