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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SCN8A-ATF1 (FusionGDB2 ID:79692) |
Fusion Gene Summary for SCN8A-ATF1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SCN8A-ATF1 | Fusion gene ID: 79692 | Hgene | Tgene | Gene symbol | SCN8A | ATF1 | Gene ID | 6334 | 2668 |
| Gene name | sodium voltage-gated channel alpha subunit 8 | glial cell derived neurotrophic factor | |
| Synonyms | BFIS5|CERIII|CIAT|EIEE13|MED|MYOCL2|NaCh6|Nav1.6|PN4 | ATF|ATF1|ATF2|HFB1-GDNF|HSCR3 | |
| Cytomap | 12q13.13 | 5p13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sodium channel protein type 8 subunit alphahNa6/Scn8a voltage-gated sodium channelsodium channel, voltage gated, type VIII, alpha subunitvoltage-gated sodium channel subunit alpha Nav1.6voltage-gated sodium channel type VIII alpha protein | glial cell line-derived neurotrophic factorastrocyte-derived trophic factor | |
| Modification date | 20200313 | 20200314 | |
| UniProtAcc | . | P18846 | |
| Ensembl transtripts involved in fusion gene | ENST00000354534, ENST00000545061, ENST00000546961, ENST00000550891, | ENST00000539132, ENST00000262053, | |
| Fusion gene scores | * DoF score | 7 X 8 X 5=280 | 10 X 16 X 7=1120 |
| # samples | 8 | 16 | |
| ** MAII score | log2(8/280*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(16/1120*10)=-2.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SCN8A [Title/Abstract] AND ATF1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SCN8A(52184286)-ATF1(51189692), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ATF1 | GO:0001755 | neural crest cell migration | 15242795 |
| Tgene | ATF1 | GO:0008284 | positive regulation of cell proliferation | 22897442 |
| Tgene | ATF1 | GO:0031175 | neuron projection development | 15242795 |
| Tgene | ATF1 | GO:0032770 | positive regulation of monooxygenase activity | 12358785 |
| Tgene | ATF1 | GO:0043524 | negative regulation of neuron apoptotic process | 8493557 |
| Tgene | ATF1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 12358785 |
| Tgene | ATF1 | GO:0048255 | mRNA stabilization | 12358785 |
| Tgene | ATF1 | GO:0051584 | regulation of dopamine uptake involved in synaptic transmission | 8493557 |
| Tgene | ATF1 | GO:0072107 | positive regulation of ureteric bud formation | 8657307 |
| Tgene | ATF1 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis | 8657307|17229286 |
| Tgene | ATF1 | GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | 10921886 |
| Fusion gene breakpoints across SCN8A (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across ATF1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LGG | TCGA-DH-A66G-01A | SCN8A | chr12 | 52184286 | - | ATF1 | chr12 | 51189692 | + |
| ChimerDB4 | LGG | TCGA-DH-A66G-01A | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + |
| ChimerDB4 | LGG | TCGA-DH-A66G | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + |
| ChimerDB4 | LGG | TCGA-DH-A66G | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + |
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Fusion Gene ORF analysis for SCN8A-ATF1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000354534 | ENST00000539132 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + |
| 5CDS-intron | ENST00000354534 | ENST00000539132 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + |
| 5CDS-intron | ENST00000545061 | ENST00000539132 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + |
| 5CDS-intron | ENST00000545061 | ENST00000539132 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + |
| In-frame | ENST00000354534 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + |
| In-frame | ENST00000354534 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + |
| In-frame | ENST00000545061 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + |
| In-frame | ENST00000545061 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + |
| intron-3CDS | ENST00000546961 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + |
| intron-3CDS | ENST00000546961 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + |
| intron-3CDS | ENST00000550891 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + |
| intron-3CDS | ENST00000550891 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + |
| intron-intron | ENST00000546961 | ENST00000539132 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + |
| intron-intron | ENST00000546961 | ENST00000539132 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + |
| intron-intron | ENST00000550891 | ENST00000539132 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + |
| intron-intron | ENST00000550891 | ENST00000539132 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000354534 | SCN8A | chr12 | 52184286 | + | ENST00000262053 | ATF1 | chr12 | 51189692 | + | 6768 | 4702 | 160 | 5424 | 1754 |
| ENST00000545061 | SCN8A | chr12 | 52184286 | + | ENST00000262053 | ATF1 | chr12 | 51189692 | + | 6521 | 4455 | 36 | 5177 | 1713 |
| ENST00000354534 | SCN8A | chr12 | 52184286 | + | ENST00000262053 | ATF1 | chr12 | 51189691 | + | 6768 | 4702 | 160 | 5424 | 1754 |
| ENST00000545061 | SCN8A | chr12 | 52184286 | + | ENST00000262053 | ATF1 | chr12 | 51189691 | + | 6521 | 4455 | 36 | 5177 | 1713 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000354534 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + | 0.000425153 | 0.99957484 |
| ENST00000545061 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189692 | + | 0.000549939 | 0.99945 |
| ENST00000354534 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + | 0.000425153 | 0.99957484 |
| ENST00000545061 | ENST00000262053 | SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + | 0.000549939 | 0.99945 |
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Fusion Genomic Features for SCN8A-ATF1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + | 3.07E-05 | 0.99996924 |
| SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + | 3.07E-05 | 0.99996924 |
| SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + | 3.07E-05 | 0.99996924 |
| SCN8A | chr12 | 52184286 | + | ATF1 | chr12 | 51189691 | + | 3.07E-05 | 0.99996924 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SCN8A-ATF1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:52184286/chr12:51189692) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | ATF1 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. {ECO:0000269|PubMed:18794154, ECO:0000269|PubMed:20980392}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1400_1421 | 1508 | 1981.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 356_380 | 1508 | 1981.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 922_942 | 1508 | 1981.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1400_1421 | 1467 | 1940.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 356_380 | 1467 | 1940.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 922_942 | 1467 | 1940.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1400_1421 | 1508 | 1981.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 356_380 | 1508 | 1981.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 922_942 | 1508 | 1981.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1400_1421 | 1467 | 1940.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 356_380 | 1467 | 1940.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 922_942 | 1467 | 1940.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 893_900 | 1508 | 1981.0 | Nucleotide binding | ATP |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 893_900 | 1467 | 1940.0 | Nucleotide binding | ATP |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 893_900 | 1508 | 1981.0 | Nucleotide binding | ATP |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 893_900 | 1467 | 1940.0 | Nucleotide binding | ATP |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 114_442 | 1508 | 1981.0 | Repeat | I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1180_1495 | 1508 | 1981.0 | Repeat | III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 735_1007 | 1508 | 1981.0 | Repeat | II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 114_442 | 1467 | 1940.0 | Repeat | I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 735_1007 | 1467 | 1940.0 | Repeat | II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 114_442 | 1508 | 1981.0 | Repeat | I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1180_1495 | 1508 | 1981.0 | Repeat | III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 735_1007 | 1508 | 1981.0 | Repeat | II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 114_442 | 1467 | 1940.0 | Repeat | I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 735_1007 | 1467 | 1940.0 | Repeat | II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1218_1230 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1250_1263 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1283_1290 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1310_1326 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1347_1399 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1422_1438 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 152_158 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 180_193 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1_132 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 212_217 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 235_253 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 274_355 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 381_387 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 409_753 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 773_783 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 804_817 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 838_839 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 858_873 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 893_921 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 943_955 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 977_1199 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1218_1230 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1250_1263 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1283_1290 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1310_1326 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1347_1399 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1422_1438 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 152_158 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 180_193 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1_132 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 212_217 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 235_253 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 274_355 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 381_387 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 409_753 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 773_783 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 804_817 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 838_839 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 858_873 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 893_921 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 943_955 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 977_1199 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1218_1230 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1250_1263 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1283_1290 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1310_1326 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1347_1399 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1422_1438 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 152_158 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 180_193 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1_132 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 212_217 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 235_253 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 274_355 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 381_387 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 409_753 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 773_783 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 804_817 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 838_839 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 858_873 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 893_921 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 943_955 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 977_1199 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1218_1230 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1250_1263 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1283_1290 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1310_1326 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1347_1399 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1422_1438 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 152_158 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 180_193 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1_132 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 212_217 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 235_253 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 274_355 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 381_387 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 409_753 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 773_783 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 804_817 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 838_839 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 858_873 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 893_921 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 943_955 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 977_1199 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1200_1217 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS1 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1231_1249 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS2 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1264_1282 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS3 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1291_1309 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS4 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1327_1346 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS5 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 133_151 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS1 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1439_1460 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS6 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 159_179 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS2 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 194_211 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS3 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 218_234 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS4 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 254_273 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS5 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 388_408 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS6 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 754_772 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS1 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 784_803 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS2 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 818_837 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS3 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 840_857 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS4 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 874_892 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS5 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 956_976 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS6 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1200_1217 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS1 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1231_1249 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS2 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1264_1282 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS3 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1291_1309 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS4 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1327_1346 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS5 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 133_151 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS1 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1439_1460 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS6 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 159_179 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS2 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 194_211 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS3 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 218_234 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS4 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 254_273 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS5 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 388_408 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS6 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 754_772 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS1 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 784_803 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS2 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 818_837 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS3 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 840_857 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS4 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 874_892 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS5 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 956_976 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS6 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1200_1217 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS1 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1231_1249 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS2 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1264_1282 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS3 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1291_1309 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS4 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1327_1346 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS5 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 133_151 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS1 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1439_1460 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS6 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 159_179 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS2 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 194_211 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS3 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 218_234 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS4 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 254_273 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS5 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 388_408 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS6 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 754_772 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS1 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 784_803 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS2 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 818_837 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS3 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 840_857 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS4 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 874_892 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS5 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 956_976 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS6 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1200_1217 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS1 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1231_1249 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS2 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1264_1282 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS3 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1291_1309 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS4 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1327_1346 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS5 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 133_151 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS1 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1439_1460 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS6 of repeat III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 159_179 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS2 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 194_211 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS3 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 218_234 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS4 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 254_273 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS5 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 388_408 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS6 of repeat I |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 754_772 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS1 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 784_803 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS2 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 818_837 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS3 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 840_857 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS4 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 874_892 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS5 of repeat II |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 956_976 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS6 of repeat II |
| Tgene | ATF1 | chr12:52184286 | chr12:51189691 | ENST00000262053 | 1 | 7 | 213_271 | 31 | 272.0 | Domain | bZIP | |
| Tgene | ATF1 | chr12:52184286 | chr12:51189691 | ENST00000262053 | 1 | 7 | 31_90 | 31 | 272.0 | Domain | KID | |
| Tgene | ATF1 | chr12:52184286 | chr12:51189692 | ENST00000262053 | 1 | 7 | 213_271 | 31 | 272.0 | Domain | bZIP | |
| Tgene | ATF1 | chr12:52184286 | chr12:51189692 | ENST00000262053 | 1 | 7 | 31_90 | 31 | 272.0 | Domain | KID | |
| Tgene | ATF1 | chr12:52184286 | chr12:51189691 | ENST00000262053 | 1 | 7 | 215_239 | 31 | 272.0 | Region | Basic motif | |
| Tgene | ATF1 | chr12:52184286 | chr12:51189691 | ENST00000262053 | 1 | 7 | 241_262 | 31 | 272.0 | Region | Leucine-zipper | |
| Tgene | ATF1 | chr12:52184286 | chr12:51189692 | ENST00000262053 | 1 | 7 | 215_239 | 31 | 272.0 | Region | Basic motif | |
| Tgene | ATF1 | chr12:52184286 | chr12:51189692 | ENST00000262053 | 1 | 7 | 241_262 | 31 | 272.0 | Region | Leucine-zipper |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1895_1924 | 1508 | 1981.0 | Domain | IQ |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1895_1924 | 1467 | 1940.0 | Domain | IQ |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1895_1924 | 1508 | 1981.0 | Domain | IQ |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1895_1924 | 1467 | 1940.0 | Domain | IQ |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1691_1713 | 1508 | 1981.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1691_1713 | 1467 | 1940.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1691_1713 | 1508 | 1981.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1691_1713 | 1467 | 1940.0 | Intramembrane | Pore-forming |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1504_1801 | 1508 | 1981.0 | Repeat | IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1180_1495 | 1467 | 1940.0 | Repeat | III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1504_1801 | 1467 | 1940.0 | Repeat | IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1504_1801 | 1508 | 1981.0 | Repeat | IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1180_1495 | 1467 | 1940.0 | Repeat | III |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1504_1801 | 1467 | 1940.0 | Repeat | IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1461_1523 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1542_1552 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1572_1583 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1602_1614 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1632_1650 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1669_1690 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1714_1742 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1766_1980 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1461_1523 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1542_1552 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1572_1583 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1602_1614 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1632_1650 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1669_1690 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1714_1742 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1766_1980 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1461_1523 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1542_1552 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1572_1583 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1602_1614 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1632_1650 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1669_1690 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1714_1742 | 1508 | 1981.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1766_1980 | 1508 | 1981.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1461_1523 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1542_1552 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1572_1583 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1602_1614 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1632_1650 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1669_1690 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1714_1742 | 1467 | 1940.0 | Topological domain | Extracellular |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1766_1980 | 1467 | 1940.0 | Topological domain | Cytoplasmic |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1524_1541 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS1 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1553_1571 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS2 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1584_1601 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS3 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1615_1631 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS4 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1651_1668 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS5 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000354534 | + | 25 | 27 | 1743_1765 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS6 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1524_1541 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS1 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1553_1571 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS2 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1584_1601 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS3 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1615_1631 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS4 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1651_1668 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS5 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189691 | ENST00000545061 | + | 23 | 25 | 1743_1765 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS6 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1524_1541 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS1 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1553_1571 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS2 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1584_1601 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS3 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1615_1631 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS4 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1651_1668 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS5 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000354534 | + | 25 | 27 | 1743_1765 | 1508 | 1981.0 | Transmembrane | Helical%3B Name%3DS6 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1524_1541 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS1 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1553_1571 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS2 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1584_1601 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS3 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1615_1631 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS4 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1651_1668 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS5 of repeat IV |
| Hgene | SCN8A | chr12:52184286 | chr12:51189692 | ENST00000545061 | + | 23 | 25 | 1743_1765 | 1467 | 1940.0 | Transmembrane | Helical%3B Name%3DS6 of repeat IV |
Top |
Fusion Gene Sequence for SCN8A-ATF1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >79692_79692_1_SCN8A-ATF1_SCN8A_chr12_52184286_ENST00000354534_ATF1_chr12_51189691_ENST00000262053_length(transcript)=6768nt_BP=4702nt GAGCGCTCCAAGATGGCGCCCACCGCAGTCCCGCCCGCCGCATCCTCGGCGCCTTTGCAGTCCGGCCGCGCCTCCCGGGCCCCGCGTTAG GGCCGCCGCTGCCTCCCTCGCCGCCGCCGCTGCCAGCTGACCTGTCCTGGACGCAGCATAACTAACGAAGCTGCTGCAGGATGAGAAGAT GGCAGCGCGGCTGCTTGCACCACCAGGCCCTGATAGTTTCAAGCCTTTCACCCCTGAGTCACTGGCAAACATTGAGAGGCGCATTGCTGA GAGCAAGCTCAAGAAACCACCAAAGGCCGATGGCAGTCATCGGGAGGACGATGAGGACAGCAAGCCCAAGCCAAACAGCGACCTGGAAGC AGGGAAGAGTTTGCCTTTCATCTACGGGGACATCCCCCAAGGCCTGGTTGCAGTTCCCCTGGAGGACTTTGACCCATACTATTTGACGCA GAAAACCTTTGTAGTATTAAACAGAGGGAAAACTCTCTTCAGATTTAGTGCCACGCCTGCCTTGTACATTTTAAGTCCTTTTAACCTGAT AAGAAGAATAGCTATTAAAATTTTGATACATTCAGTATTTAGCATGATCATTATGTGCACTATTTTGACCAACTGTGTATTCATGACTTT TAGTAACCCTCCTGACTGGTCGAAGAATGTGGAGTACACGTTCACAGGGATTTATACATTTGAATCACTAGTGAAAATCATTGCAAGAGG TTTCTGCATAGATGGCTTTACCTTTTTACGGGACCCATGGAACTGGTTAGATTTCAGTGTCATCATGATGGCGTATATAACAGAGTTTGT AAACCTAGGCAATGTTTCAGCTCTACGCACTTTCAGGGTACTGAGGGCTTTGAAAACTATTTCGGTAATCCCAGGCCTGAAGACAATTGT GGGTGCCCTGATTCAGTCTGTGAAGAAACTGTCAGATGTGATGATCCTGACAGTGTTCTGCCTGAGTGTTTTTGCCTTGATCGGACTGCA GCTGTTCATGGGGAACCTTCGAAACAAGTGTGTTGTGTGGCCCATAAACTTCAACGAGAGCTATCTTGAAAATGGCACCAAAGGCTTTGA TTGGGAAGAGTATATCAACAATAAAACAAATTTCTACACAGTTCCTGGCATGCTGGAACCTTTACTCTGTGGGAACAGTTCTGATGCTGG GCAATGCCCAGAGGGATACCAGTGTATGAAAGCAGGAAGGAACCCCAACTATGGTTACACAAGTTTTGACACTTTTAGCTGGGCCTTCTT GGCATTATTTCGCCTTATGACCCAGGACTATTGGGAAAACTTGTATCAATTGACTTTACGAGCAGCCGGGAAAACATACATGATCTTCTT CGTCTTGGTCATCTTTGTGGGTTCTTTCTATCTGGTGAACTTGATCTTGGCTGTGGTGGCCATGGCTTATGAAGAACAGAATCAGGCAAC ACTGGAGGAGGCAGAACAAAAAGAGGCTGAATTTAAAGCAATGTTGGAGCAACTTAAGAAGCAACAGGAAGAGGCACAGGCTGCTGCGAT GGCCACTTCAGCAGGAACTGTCTCAGAAGATGCCATAGAGGAAGAAGGTGAAGAAGGAGGGGGCTCCCCTCGGAGCTCTTCTGAAATCTC TAAACTCAGCTCAAAGAGTGCAAAGGAAAGACGTAACAGGAGAAAGAAGAGGAAGCAAAAGGAACTCTCTGAAGGAGAGGAGAAAGGGGA TCCCGAGAAGGTGTTTAAGTCAGAGTCAGAAGATGGCATGAGAAGGAAGGCCTTTCGGCTGCCAGACAACAGAATAGGGAGGAAATTTTC CATCATGAATCAGTCACTGCTCAGCATCCCAGGCTCGCCCTTCCTCTCCCGCCACAACAGCAAGAGCAGCATCTTCAGTTTCAGGGGACC TGGGCGGTTCCGAGACCCGGGCTCCGAGAATGAGTTCGCGGATGACGAGCACAGCACGGTGGAGGAGAGCGAGGGCCGCCGGGACTCCCT CTTCATCCCCATCCGGGCCCGCGAGCGCCGGAGCAGCTACAGCGGCTACAGCGGCTACAGCCAGGGCAGCCGCTCCTCGCGCATCTTCCC CAGCCTGCGGCGCAGCGTGAAGCGCAACAGCACGGTGGACTGCAACGGCGTGGTGTCCCTCATCGGCGGCCCCGGCTCCCACATCGGCGG GCGTCTCCTGCCAGAGGCTACAACTGAGGTGGAAATTAAGAAGAAAGGCCCTGGATCTCTTTTAGTTTCCATGGACCAATTAGCCTCCTA CGGGCGGAAGGACAGAATCAACAGTATAATGAGTGTTGTTACAAATACACTAGTAGAAGAACTGGAAGAGTCTCAGAGAAAGTGCCCGCC ATGCTGGTATAAATTTGCCAACACTTTCCTCATCTGGGAGTGCCACCCCTACTGGATAAAACTGAAAGAGATTGTGAACTTGATAGTTAT GGACCCTTTTGTGGATTTAGCCATCACCATCTGCATCGTCCTGAATACACTGTTTATGGCAATGGAGCACCATCCTATGACACCACAATT TGAACATGTCTTGGCTGTAGGAAATCTGGTTTTCACTGGAATTTTCACAGCGGAAATGTTCCTGAAGCTCATAGCCATGGATCCCTACTA TTATTTCCAAGAAGGTTGGAACATTTTTGACGGATTTATTGTCTCCCTCAGTTTAATGGAACTGAGTCTAGCAGACGTGGAGGGGCTTTC AGTGCTGCGATCTTTCCGATTGCTCCGAGTCTTCAAATTGGCCAAATCCTGGCCCACCCTGAACATGCTAATCAAGATTATTGGAAATTC AGTGGGTGCCCTGGGCAACCTGACACTGGTGCTGGCCATTATTGTCTTCATCTTTGCCGTGGTGGGGATGCAACTCTTTGGAAAAAGCTA CAAAGAGTGTGTCTGCAAGATCAACCAGGACTGTGAACTCCCTCGCTGGCATATGCATGACTTTTTCCATTCCTTCCTCATTGTCTTTCG AGTGTTGTGCGGGGAGTGGATTGAGACCATGTGGGACTGCATGGAAGTGGCAGGCCAGGCCATGTGCCTCATTGTCTTTATGATGGTCAT GGTGATTGGCAACTTGGTGGTGCTGAACCTGTTTCTGGCCTTGCTCCTGAGCTCCTTCAGTGCAGACAACCTGGCTGCCACAGATGACGA TGGGGAAATGAACAACCTCCAGATCTCAGTGATCCGTATCAAGAAGGGTGTGGCCTGGACCAAACTAAAGGTGCACGCCTTCATGCAGGC CCACTTTAAGCAGCGTGAGGCTGATGAGGTGAAGCCTCTGGATGAGTTGTATGAAAAGAAGGCCAACTGTATCGCCAATCACACCGGTGC AGACATCCACCGGAATGGTGACTTCCAGAAGAATGGCAATGGCACAACCAGCGGCATTGGCAGCAGCGTGGAGAAGTACATCATTGATGA GGACCACATGTCCTTCATCAACAACCCCAACTTGACTGTACGGGTACCCATTGCTGTGGGCGAGTCTGACTTTGAGAACCTCAACACAGA GGATGTTAGCAGCGAGTCGGATCCTGAAGGCAGCAAAGATAAACTAGATGACACCAGCTCCTCTGAAGGAAGCACCATTGATATCAAACC AGAAGTAGAAGAGGTCCCTGTGGAACAGCCTGAGGAATACTTGGATCCAGATGCCTGCTTCACAGAAGGTTGTGTCCAGCGGTTCAAGTG CTGCCAGGTCAACATCGAGGAAGGGCTAGGCAAGTCTTGGTGGATCCTGCGGAAAACCTGCTTCCTCATCGTGGAGCACAACTGGTTTGA GACCTTCATCATCTTCATGATTCTGCTGAGCAGTGGCGCCCTGGCCTTCGAGGACATCTACATTGAGCAGAGAAAGACCATCCGCACCAT CCTGGAATATGCTGACAAAGTCTTCACCTATATCTTCATCCTGGAGATGTTGCTCAAGTGGACAGCCTATGGCTTCGTCAAGTTCTTCAC CAATGCCTGGTGTTGGCTGGACTTCCTCATTGTGGCTGTCTCTTTAGTCAGCCTTATAGCTAATGCCCTGGGCTACTCGGAACTAGGTGC CATAAAGTCCCTTAGGACCCTAAGAGCTTTGAGACCCTTAAGAGCCTTATCACGATTTGAAGGGATGAGGGTGGTGGTGAATGCCTTGGT GGGCGCCATCCCCTCCATCATGAATGTGCTGCTGGTGTGTCTCATCTTCTGGCTGATTTTCAGCATCATGGGAGTTAACTTGTTTGCGGG AAAGTACCACTACTGCTTTAATGAGACTTCTGAAATCCGATTTGAAATTGAAGATGTCAACAATAAAACTGAATGTGAAAAGCTTATGGA GGGGAACAATACAGAGATCAGATGGAAGAACGTGAAGATCAACTTTGACAATGTTGGGGCAGGATACCTGGCCCTTCTTCAAGTAGCAAC CTTCAAAGGCTGGATGGACATCATGTATGCAGCTGTAGATTCCCGGAAGCCTGATGAGCAGCCTAAGTATGAGGACAATATCTACATGTA CATCTATTTTGTCATCTTCATCATCTTCGGCTCCTTCTTCACCCTGAACCTGTTCATTGGTGTCATCATTGATAACTTCAATCAACAAAA GAAAAAGTTCGGAGGTCAGGACATCTTCATGACCGAAGAACAGAAGAAGTACTACAATGCCATGAAAAAGCTGGGCTCAAAGAAGCCACA GAAACCTATTCCCCGCCCCTTGGTATCATCTTTATCAGAAAGTGAGGAGTCCCAGGACTCATCCGACAGCATAGGCTCCTCACAGAAAGC CCACGGGATCCTAGCACGGCGCCCATCTTACAGAAAAATTTTGAAAGACTTATCTTCTGAAGATACACGGGGCAGAAAAGGAGACGGAGA AAATTCTGGAGTTTCTGCTGCTGTCACTTCTATGTCTGTTCCAACTCCCATCTATCAGACTAGCAGCGGACAGTACATTGCCATTGCCCC AAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCA AGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGG AGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTC TCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAA GAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGA TCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGGACATGCATAAAAATTAAATGGATTTCCTAGTGGAGTTT TATAAATTAAAAGGTCAAAACTGAAGCTTTTTATTTAGGCTTTTCCAAATCAAGGATAAATATCTTACGCACGATATCTAGTGACAGAGG AGAAAGTGGAAAATGACCTCAAGGAAGCTACGGGCACAACTGGAAGCTTTGTAGAAATTAAACATATTCAAGGAGCAAGAAATGAACTTT CAGCAGTCTAAATTTTCTAAATAACCAATAGTTGCCAATCTAAAATGGCAGAGAAGATGAAATTTGATAAACTGAATTTTTTTTAAAAAT CCATTTACCCTACAGGTTTGCATTTGTTTGCTGAAATTTACCTTTTTTTAGTTATATATATGTGTGTGTGTGTGTGTAATTTCTGCCAAT AAATTCTAAATTACAAAGGTAAGAGAAAACCTAGTACATTACTAAATATATAAAGTATATGTTCTGATTATGTATACTTGTTCTAGTGTC AAGTCTTTTTAAGTGGGTTTTTAAAAGTTTGTTATTGGACTTGAATGGATTTTTGAGACTAGGTTAATTATTTTTGAGGTCTTATCCTAA AAGGCATCTAAGGTACATGAATGGAGTATGGTGATTTTATAACATTTTTTATCAGAATGGAAAAAGAACTGTTTAAAAGTTTGATACTTT TAAATAGTTGGTTTTTTTGCTTACTCTGGTAATGATTTTCTACAAATACATAATAAATTGTTTTTTTGAGTCTATATTCTGTATGCAGTT GAATATCCATTACTTATTCTGCTGTGCTTTAATAGAATGGAATGTTTACAGGCCCTTAAAATATTATTTTTAAAAAACCTTCTGAAGATA CATACCAAAGTTTTTCCAAGAAGATTTTATAATCAATTTAATAATGTAAGGTTTATCAGATTCTATAATAGTATAGTTATTAAGGCAATT TTATGTTAGAGACTATTTTGTAATGTAGTGAGTGGTACCTTTATAAGAAAAGTGACTGCCAATATATTTTTATAGCTGATCTTTATAAAT TCTAATGTTGAGTTTTTAATGATTATTTTAAATGTTTATATAGTTTAGTAAAATTTGCATCTCAAAGTATCATTTTTATATTATGGGACG TTTTCAGATTGGCTAATATTTGCATTGTAAATTTTGTATGCAGTTTATCTAAAATTCAAAAATACTGTCAGTACACCAGCGTTTAACATC TATATTCCAATTTGTATACAGTTTAAAATTGTACTGCAAAACTATTGTGTGCTCTTACACAGTATGCATCATATTGTTGTCTGTGAAATT >79692_79692_1_SCN8A-ATF1_SCN8A_chr12_52184286_ENST00000354534_ATF1_chr12_51189691_ENST00000262053_length(amino acids)=1754AA_BP=1514 MLQDEKMAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDF DPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESL VKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSV FALIGLQLFMGNLRNKCVVWPINFNESYLENGTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFD TFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQE EAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDN RIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGS RSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEATTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEE SQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKL IAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGM QLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADN LAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQREADEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSV EKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEG CVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAY GFVKFFTNAWCWLDFLIVAVSLVSLIANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIM GVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKY EDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLVSSLSESEESQDSSDS IGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENSGVSAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQGLQTLTMT NSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTVVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAA -------------------------------------------------------------- >79692_79692_2_SCN8A-ATF1_SCN8A_chr12_52184286_ENST00000354534_ATF1_chr12_51189692_ENST00000262053_length(transcript)=6768nt_BP=4702nt GAGCGCTCCAAGATGGCGCCCACCGCAGTCCCGCCCGCCGCATCCTCGGCGCCTTTGCAGTCCGGCCGCGCCTCCCGGGCCCCGCGTTAG GGCCGCCGCTGCCTCCCTCGCCGCCGCCGCTGCCAGCTGACCTGTCCTGGACGCAGCATAACTAACGAAGCTGCTGCAGGATGAGAAGAT GGCAGCGCGGCTGCTTGCACCACCAGGCCCTGATAGTTTCAAGCCTTTCACCCCTGAGTCACTGGCAAACATTGAGAGGCGCATTGCTGA GAGCAAGCTCAAGAAACCACCAAAGGCCGATGGCAGTCATCGGGAGGACGATGAGGACAGCAAGCCCAAGCCAAACAGCGACCTGGAAGC AGGGAAGAGTTTGCCTTTCATCTACGGGGACATCCCCCAAGGCCTGGTTGCAGTTCCCCTGGAGGACTTTGACCCATACTATTTGACGCA GAAAACCTTTGTAGTATTAAACAGAGGGAAAACTCTCTTCAGATTTAGTGCCACGCCTGCCTTGTACATTTTAAGTCCTTTTAACCTGAT AAGAAGAATAGCTATTAAAATTTTGATACATTCAGTATTTAGCATGATCATTATGTGCACTATTTTGACCAACTGTGTATTCATGACTTT TAGTAACCCTCCTGACTGGTCGAAGAATGTGGAGTACACGTTCACAGGGATTTATACATTTGAATCACTAGTGAAAATCATTGCAAGAGG TTTCTGCATAGATGGCTTTACCTTTTTACGGGACCCATGGAACTGGTTAGATTTCAGTGTCATCATGATGGCGTATATAACAGAGTTTGT AAACCTAGGCAATGTTTCAGCTCTACGCACTTTCAGGGTACTGAGGGCTTTGAAAACTATTTCGGTAATCCCAGGCCTGAAGACAATTGT GGGTGCCCTGATTCAGTCTGTGAAGAAACTGTCAGATGTGATGATCCTGACAGTGTTCTGCCTGAGTGTTTTTGCCTTGATCGGACTGCA GCTGTTCATGGGGAACCTTCGAAACAAGTGTGTTGTGTGGCCCATAAACTTCAACGAGAGCTATCTTGAAAATGGCACCAAAGGCTTTGA TTGGGAAGAGTATATCAACAATAAAACAAATTTCTACACAGTTCCTGGCATGCTGGAACCTTTACTCTGTGGGAACAGTTCTGATGCTGG GCAATGCCCAGAGGGATACCAGTGTATGAAAGCAGGAAGGAACCCCAACTATGGTTACACAAGTTTTGACACTTTTAGCTGGGCCTTCTT GGCATTATTTCGCCTTATGACCCAGGACTATTGGGAAAACTTGTATCAATTGACTTTACGAGCAGCCGGGAAAACATACATGATCTTCTT CGTCTTGGTCATCTTTGTGGGTTCTTTCTATCTGGTGAACTTGATCTTGGCTGTGGTGGCCATGGCTTATGAAGAACAGAATCAGGCAAC ACTGGAGGAGGCAGAACAAAAAGAGGCTGAATTTAAAGCAATGTTGGAGCAACTTAAGAAGCAACAGGAAGAGGCACAGGCTGCTGCGAT GGCCACTTCAGCAGGAACTGTCTCAGAAGATGCCATAGAGGAAGAAGGTGAAGAAGGAGGGGGCTCCCCTCGGAGCTCTTCTGAAATCTC TAAACTCAGCTCAAAGAGTGCAAAGGAAAGACGTAACAGGAGAAAGAAGAGGAAGCAAAAGGAACTCTCTGAAGGAGAGGAGAAAGGGGA TCCCGAGAAGGTGTTTAAGTCAGAGTCAGAAGATGGCATGAGAAGGAAGGCCTTTCGGCTGCCAGACAACAGAATAGGGAGGAAATTTTC CATCATGAATCAGTCACTGCTCAGCATCCCAGGCTCGCCCTTCCTCTCCCGCCACAACAGCAAGAGCAGCATCTTCAGTTTCAGGGGACC TGGGCGGTTCCGAGACCCGGGCTCCGAGAATGAGTTCGCGGATGACGAGCACAGCACGGTGGAGGAGAGCGAGGGCCGCCGGGACTCCCT CTTCATCCCCATCCGGGCCCGCGAGCGCCGGAGCAGCTACAGCGGCTACAGCGGCTACAGCCAGGGCAGCCGCTCCTCGCGCATCTTCCC CAGCCTGCGGCGCAGCGTGAAGCGCAACAGCACGGTGGACTGCAACGGCGTGGTGTCCCTCATCGGCGGCCCCGGCTCCCACATCGGCGG GCGTCTCCTGCCAGAGGCTACAACTGAGGTGGAAATTAAGAAGAAAGGCCCTGGATCTCTTTTAGTTTCCATGGACCAATTAGCCTCCTA CGGGCGGAAGGACAGAATCAACAGTATAATGAGTGTTGTTACAAATACACTAGTAGAAGAACTGGAAGAGTCTCAGAGAAAGTGCCCGCC ATGCTGGTATAAATTTGCCAACACTTTCCTCATCTGGGAGTGCCACCCCTACTGGATAAAACTGAAAGAGATTGTGAACTTGATAGTTAT GGACCCTTTTGTGGATTTAGCCATCACCATCTGCATCGTCCTGAATACACTGTTTATGGCAATGGAGCACCATCCTATGACACCACAATT TGAACATGTCTTGGCTGTAGGAAATCTGGTTTTCACTGGAATTTTCACAGCGGAAATGTTCCTGAAGCTCATAGCCATGGATCCCTACTA TTATTTCCAAGAAGGTTGGAACATTTTTGACGGATTTATTGTCTCCCTCAGTTTAATGGAACTGAGTCTAGCAGACGTGGAGGGGCTTTC AGTGCTGCGATCTTTCCGATTGCTCCGAGTCTTCAAATTGGCCAAATCCTGGCCCACCCTGAACATGCTAATCAAGATTATTGGAAATTC AGTGGGTGCCCTGGGCAACCTGACACTGGTGCTGGCCATTATTGTCTTCATCTTTGCCGTGGTGGGGATGCAACTCTTTGGAAAAAGCTA CAAAGAGTGTGTCTGCAAGATCAACCAGGACTGTGAACTCCCTCGCTGGCATATGCATGACTTTTTCCATTCCTTCCTCATTGTCTTTCG AGTGTTGTGCGGGGAGTGGATTGAGACCATGTGGGACTGCATGGAAGTGGCAGGCCAGGCCATGTGCCTCATTGTCTTTATGATGGTCAT GGTGATTGGCAACTTGGTGGTGCTGAACCTGTTTCTGGCCTTGCTCCTGAGCTCCTTCAGTGCAGACAACCTGGCTGCCACAGATGACGA TGGGGAAATGAACAACCTCCAGATCTCAGTGATCCGTATCAAGAAGGGTGTGGCCTGGACCAAACTAAAGGTGCACGCCTTCATGCAGGC CCACTTTAAGCAGCGTGAGGCTGATGAGGTGAAGCCTCTGGATGAGTTGTATGAAAAGAAGGCCAACTGTATCGCCAATCACACCGGTGC AGACATCCACCGGAATGGTGACTTCCAGAAGAATGGCAATGGCACAACCAGCGGCATTGGCAGCAGCGTGGAGAAGTACATCATTGATGA GGACCACATGTCCTTCATCAACAACCCCAACTTGACTGTACGGGTACCCATTGCTGTGGGCGAGTCTGACTTTGAGAACCTCAACACAGA GGATGTTAGCAGCGAGTCGGATCCTGAAGGCAGCAAAGATAAACTAGATGACACCAGCTCCTCTGAAGGAAGCACCATTGATATCAAACC AGAAGTAGAAGAGGTCCCTGTGGAACAGCCTGAGGAATACTTGGATCCAGATGCCTGCTTCACAGAAGGTTGTGTCCAGCGGTTCAAGTG CTGCCAGGTCAACATCGAGGAAGGGCTAGGCAAGTCTTGGTGGATCCTGCGGAAAACCTGCTTCCTCATCGTGGAGCACAACTGGTTTGA GACCTTCATCATCTTCATGATTCTGCTGAGCAGTGGCGCCCTGGCCTTCGAGGACATCTACATTGAGCAGAGAAAGACCATCCGCACCAT CCTGGAATATGCTGACAAAGTCTTCACCTATATCTTCATCCTGGAGATGTTGCTCAAGTGGACAGCCTATGGCTTCGTCAAGTTCTTCAC CAATGCCTGGTGTTGGCTGGACTTCCTCATTGTGGCTGTCTCTTTAGTCAGCCTTATAGCTAATGCCCTGGGCTACTCGGAACTAGGTGC CATAAAGTCCCTTAGGACCCTAAGAGCTTTGAGACCCTTAAGAGCCTTATCACGATTTGAAGGGATGAGGGTGGTGGTGAATGCCTTGGT GGGCGCCATCCCCTCCATCATGAATGTGCTGCTGGTGTGTCTCATCTTCTGGCTGATTTTCAGCATCATGGGAGTTAACTTGTTTGCGGG AAAGTACCACTACTGCTTTAATGAGACTTCTGAAATCCGATTTGAAATTGAAGATGTCAACAATAAAACTGAATGTGAAAAGCTTATGGA GGGGAACAATACAGAGATCAGATGGAAGAACGTGAAGATCAACTTTGACAATGTTGGGGCAGGATACCTGGCCCTTCTTCAAGTAGCAAC CTTCAAAGGCTGGATGGACATCATGTATGCAGCTGTAGATTCCCGGAAGCCTGATGAGCAGCCTAAGTATGAGGACAATATCTACATGTA CATCTATTTTGTCATCTTCATCATCTTCGGCTCCTTCTTCACCCTGAACCTGTTCATTGGTGTCATCATTGATAACTTCAATCAACAAAA GAAAAAGTTCGGAGGTCAGGACATCTTCATGACCGAAGAACAGAAGAAGTACTACAATGCCATGAAAAAGCTGGGCTCAAAGAAGCCACA GAAACCTATTCCCCGCCCCTTGGTATCATCTTTATCAGAAAGTGAGGAGTCCCAGGACTCATCCGACAGCATAGGCTCCTCACAGAAAGC CCACGGGATCCTAGCACGGCGCCCATCTTACAGAAAAATTTTGAAAGACTTATCTTCTGAAGATACACGGGGCAGAAAAGGAGACGGAGA AAATTCTGGAGTTTCTGCTGCTGTCACTTCTATGTCTGTTCCAACTCCCATCTATCAGACTAGCAGCGGACAGTACATTGCCATTGCCCC AAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCA AGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGG AGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTC TCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAA GAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGA TCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGGACATGCATAAAAATTAAATGGATTTCCTAGTGGAGTTT TATAAATTAAAAGGTCAAAACTGAAGCTTTTTATTTAGGCTTTTCCAAATCAAGGATAAATATCTTACGCACGATATCTAGTGACAGAGG AGAAAGTGGAAAATGACCTCAAGGAAGCTACGGGCACAACTGGAAGCTTTGTAGAAATTAAACATATTCAAGGAGCAAGAAATGAACTTT CAGCAGTCTAAATTTTCTAAATAACCAATAGTTGCCAATCTAAAATGGCAGAGAAGATGAAATTTGATAAACTGAATTTTTTTTAAAAAT CCATTTACCCTACAGGTTTGCATTTGTTTGCTGAAATTTACCTTTTTTTAGTTATATATATGTGTGTGTGTGTGTGTAATTTCTGCCAAT AAATTCTAAATTACAAAGGTAAGAGAAAACCTAGTACATTACTAAATATATAAAGTATATGTTCTGATTATGTATACTTGTTCTAGTGTC AAGTCTTTTTAAGTGGGTTTTTAAAAGTTTGTTATTGGACTTGAATGGATTTTTGAGACTAGGTTAATTATTTTTGAGGTCTTATCCTAA AAGGCATCTAAGGTACATGAATGGAGTATGGTGATTTTATAACATTTTTTATCAGAATGGAAAAAGAACTGTTTAAAAGTTTGATACTTT TAAATAGTTGGTTTTTTTGCTTACTCTGGTAATGATTTTCTACAAATACATAATAAATTGTTTTTTTGAGTCTATATTCTGTATGCAGTT GAATATCCATTACTTATTCTGCTGTGCTTTAATAGAATGGAATGTTTACAGGCCCTTAAAATATTATTTTTAAAAAACCTTCTGAAGATA CATACCAAAGTTTTTCCAAGAAGATTTTATAATCAATTTAATAATGTAAGGTTTATCAGATTCTATAATAGTATAGTTATTAAGGCAATT TTATGTTAGAGACTATTTTGTAATGTAGTGAGTGGTACCTTTATAAGAAAAGTGACTGCCAATATATTTTTATAGCTGATCTTTATAAAT TCTAATGTTGAGTTTTTAATGATTATTTTAAATGTTTATATAGTTTAGTAAAATTTGCATCTCAAAGTATCATTTTTATATTATGGGACG TTTTCAGATTGGCTAATATTTGCATTGTAAATTTTGTATGCAGTTTATCTAAAATTCAAAAATACTGTCAGTACACCAGCGTTTAACATC TATATTCCAATTTGTATACAGTTTAAAATTGTACTGCAAAACTATTGTGTGCTCTTACACAGTATGCATCATATTGTTGTCTGTGAAATT >79692_79692_2_SCN8A-ATF1_SCN8A_chr12_52184286_ENST00000354534_ATF1_chr12_51189692_ENST00000262053_length(amino acids)=1754AA_BP=1514 MLQDEKMAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDF DPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESL VKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSV FALIGLQLFMGNLRNKCVVWPINFNESYLENGTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFD TFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQE EAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDN RIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGS RSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEATTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEE SQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKL IAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGM QLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADN LAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQREADEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSV EKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEG CVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAY GFVKFFTNAWCWLDFLIVAVSLVSLIANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIM GVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKY EDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLVSSLSESEESQDSSDS IGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENSGVSAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQGLQTLTMT NSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTVVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAA -------------------------------------------------------------- >79692_79692_3_SCN8A-ATF1_SCN8A_chr12_52184286_ENST00000545061_ATF1_chr12_51189691_ENST00000262053_length(transcript)=6521nt_BP=4455nt AGCTGACCTGTCCTGGACGCAGCATAACTAACGAAGCTGCTGCAGGATGAGAAGATGGCAGCGCGGCTGCTTGCACCACCAGGCCCTGAT AGTTTCAAGCCTTTCACCCCTGAGTCACTGGCAAACATTGAGAGGCGCATTGCTGAGAGCAAGCTCAAGAAACCACCAAAGGCCGATGGC AGTCATCGGGAGGACGATGAGGACAGCAAGCCCAAGCCAAACAGCGACCTGGAAGCAGGGAAGAGTTTGCCTTTCATCTACGGGGACATC CCCCAAGGCCTGGTTGCAGTTCCCCTGGAGGACTTTGACCCATACTATTTGACGCAGAAAACCTTTGTAGTATTAAACAGAGGGAAAACT CTCTTCAGATTTAGTGCCACGCCTGCCTTGTACATTTTAAGTCCTTTTAACCTGATAAGAAGAATAGCTATTAAAATTTTGATACATTCA GTATTTAGCATGATCATTATGTGCACTATTTTGACCAACTGTGTATTCATGACTTTTAGTAACCCTCCTGACTGGTCGAAGAATGTGGAG TACACGTTCACAGGGATTTATACATTTGAATCACTAGTGAAAATCATTGCAAGAGGTTTCTGCATAGATGGCTTTACCTTTTTACGGGAC CCATGGAACTGGTTAGATTTCAGTGTCATCATGATGGCGTATATAACAGAGTTTGTAAACCTAGGCAATGTTTCAGCTCTACGCACTTTC AGGGTACTGAGGGCTTTGAAAACTATTTCGGTAATCCCAGGCCTGAAGACAATTGTGGGTGCCCTGATTCAGTCTGTGAAGAAACTGTCA GATGTGATGATCCTGACAGTGTTCTGCCTGAGTGTTTTTGCCTTGATCGGACTGCAGCTGTTCATGGGGAACCTTCGAAACAAGTGTGTT GTGTGGCCCATAAACTTCAACGAGAGCTATCTTGAAAATGGCACCAAAGGCTTTGATTGGGAAGAGTATATCAACAATAAAACAAATTTC TACACAGTTCCTGGCATGCTGGAACCTTTACTCTGTGGGAACAGTTCTGATGCTGGGCAATGCCCAGAGGGATACCAGTGTATGAAAGCA GGAAGGAACCCCAACTATGGTTACACAAGTTTTGACACTTTTAGCTGGGCCTTCTTGGCATTATTTCGCCTTATGACCCAGGACTATTGG GAAAACTTGTATCAATTGACTTTACGAGCAGCCGGGAAAACATACATGATCTTCTTCGTCTTGGTCATCTTTGTGGGTTCTTTCTATCTG GTGAACTTGATCTTGGCTGTGGTGGCCATGGCTTATGAAGAACAGAATCAGGCAACACTGGAGGAGGCAGAACAAAAAGAGGCTGAATTT AAAGCAATGTTGGAGCAACTTAAGAAGCAACAGGAAGAGGCACAGGCTGCTGCGATGGCCACTTCAGCAGGAACTGTCTCAGAAGATGCC ATAGAGGAAGAAGGTGAAGAAGGAGGGGGCTCCCCTCGGAGCTCTTCTGAAATCTCTAAACTCAGCTCAAAGAGTGCAAAGGAAAGACGT AACAGGAGAAAGAAGAGGAAGCAAAAGGAACTCTCTGAAGGAGAGGAGAAAGGGGATCCCGAGAAGGTGTTTAAGTCAGAGTCAGAAGAT GGCATGAGAAGGAAGGCCTTTCGGCTGCCAGACAACAGAATAGGGAGGAAATTTTCCATCATGAATCAGTCACTGCTCAGCATCCCAGGC TCGCCCTTCCTCTCCCGCCACAACAGCAAGAGCAGCATCTTCAGTTTCAGGGGACCTGGGCGGTTCCGAGACCCGGGCTCCGAGAATGAG TTCGCGGATGACGAGCACAGCACGGTGGAGGAGAGCGAGGGCCGCCGGGACTCCCTCTTCATCCCCATCCGGGCCCGCGAGCGCCGGAGC AGCTACAGCGGCTACAGCGGCTACAGCCAGGGCAGCCGCTCCTCGCGCATCTTCCCCAGCCTGCGGCGCAGCGTGAAGCGCAACAGCACG GTGGACTGCAACGGCGTGGTGTCCCTCATCGGCGGCCCCGGCTCCCACATCGGCGGGCGTCTCCTGCCAGAGGCTACAACTGAGGTGGAA ATTAAGAAGAAAGGCCCTGGATCTCTTTTAGTTTCCATGGACCAATTAGCCTCCTACGGGCGGAAGGACAGAATCAACAGTATAATGAGT GTTGTTACAAATACACTAGTAGAAGAACTGGAAGAGTCTCAGAGAAAGTGCCCGCCATGCTGGTATAAATTTGCCAACACTTTCCTCATC TGGGAGTGCCACCCCTACTGGATAAAACTGAAAGAGATTGTGAACTTGATAGTTATGGACCCTTTTGTGGATTTAGCCATCACCATCTGC ATCGTCCTGAATACACTGTTTATGGCAATGGAGCACCATCCTATGACACCACAATTTGAACATGTCTTGGCTGTAGGAAATCTGGTTTTC ACTGGAATTTTCACAGCGGAAATGTTCCTGAAGCTCATAGCCATGGATCCCTACTATTATTTCCAAGAAGGTTGGAACATTTTTGACGGA TTTATTGTCTCCCTCAGTTTAATGGAACTGAGTCTAGCAGACGTGGAGGGGCTTTCAGTGCTGCGATCTTTCCGATTGCTCCGAGTCTTC AAATTGGCCAAATCCTGGCCCACCCTGAACATGCTAATCAAGATTATTGGAAATTCAGTGGGTGCCCTGGGCAACCTGACACTGGTGCTG GCCATTATTGTCTTCATCTTTGCCGTGGTGGGGATGCAACTCTTTGGAAAAAGCTACAAAGAGTGTGTCTGCAAGATCAACCAGGACTGT GAACTCCCTCGCTGGCATATGCATGACTTTTTCCATTCCTTCCTCATTGTCTTTCGAGTGTTGTGCGGGGAGTGGATTGAGACCATGTGG GACTGCATGGAAGTGGCAGGCCAGGCCATGTGCCTCATTGTCTTTATGATGGTCATGGTGATTGGCAACTTGGTGGTGCTGAACCTGTTT CTGGCCTTGCTCCTGAGCTCCTTCAGTGCAGACAACCTGGCTGCCACAGATGACGATGGGGAAATGAACAACCTCCAGATCTCAGTGATC CGTATCAAGAAGGGTGTGGCCTGGACCAAACTAAAGGTGCACGCCTTCATGCAGGCCCACTTTAAGCAGCGTGAGGCTGATGAGGTGAAG CCTCTGGATGAGTTGTATGAAAAGAAGGCCAACTGTATCGCCAATCACACCGGTGCAGACATCCACCGGAATGGTGACTTCCAGAAGAAT GGCAATGGCACAACCAGCGGCATTGGCAGCAGCGTGGAGAAGTACATCATTGATGAGGACCACATGTCCTTCATCAACAACCCCAACTTG ACTGTACGGGTACCCATTGCTGTGGGCGAGTCTGACTTTGAGAACCTCAACACAGAGGATGTTAGCAGCGAGTCGGATCCTGAAGGCAGC AAAGATAAACTAGATGACACCAGCTCCTCTGAAGGAAGCACCATTGATATCAAACCAGAAGTAGAAGAGGTCCCTGTGGAACAGCCTGAG GAATACTTGGATCCAGATGCCTGCTTCACAGAAGGTTGTGTCCAGCGGTTCAAGTGCTGCCAGGTCAACATCGAGGAAGGGCTAGGCAAG TCTTGGTGGATCCTGCGGAAAACCTGCTTCCTCATCGTGGAGCACAACTGGTTTGAGACCTTCATCATCTTCATGATTCTGCTGAGCAGT GGCGCCCTGGCCTTCGAGGACATCTACATTGAGCAGAGAAAGACCATCCGCACCATCCTGGAATATGCTGACAAAGTCTTCACCTATATC TTCATCCTGGAGATGTTGCTCAAGTGGACAGCCTATGGCTTCGTCAAGTTCTTCACCAATGCCTGGTGTTGGCTGGACTTCCTCATTGTG GCTGTGGTGGTGAATGCCTTGGTGGGCGCCATCCCCTCCATCATGAATGTGCTGCTGGTGTGTCTCATCTTCTGGCTGATTTTCAGCATC ATGGGAGTTAACTTGTTTGCGGGAAAGTACCACTACTGCTTTAATGAGACTTCTGAAATCCGATTTGAAATTGAAGATGTCAACAATAAA ACTGAATGTGAAAAGCTTATGGAGGGGAACAATACAGAGATCAGATGGAAGAACGTGAAGATCAACTTTGACAATGTTGGGGCAGGATAC CTGGCCCTTCTTCAAGTAGCAACCTTCAAAGGCTGGATGGACATCATGTATGCAGCTGTAGATTCCCGGAAGCCTGATGAGCAGCCTAAG TATGAGGACAATATCTACATGTACATCTATTTTGTCATCTTCATCATCTTCGGCTCCTTCTTCACCCTGAACCTGTTCATTGGTGTCATC ATTGATAACTTCAATCAACAAAAGAAAAAGTTCGGAGGTCAGGACATCTTCATGACCGAAGAACAGAAGAAGTACTACAATGCCATGAAA AAGCTGGGCTCAAAGAAGCCACAGAAACCTATTCCCCGCCCCTTGGTATCATCTTTATCAGAAAGTGAGGAGTCCCAGGACTCATCCGAC AGCATAGGCTCCTCACAGAAAGCCCACGGGATCCTAGCACGGCGCCCATCTTACAGAAAAATTTTGAAAGACTTATCTTCTGAAGATACA CGGGGCAGAAAAGGAGACGGAGAAAATTCTGGAGTTTCTGCTGCTGTCACTTCTATGTCTGTTCCAACTCCCATCTATCAGACTAGCAGC GGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATG ACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAG GTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATG ACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCT GCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATA GAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGGACATGCATAAAAATT AAATGGATTTCCTAGTGGAGTTTTATAAATTAAAAGGTCAAAACTGAAGCTTTTTATTTAGGCTTTTCCAAATCAAGGATAAATATCTTA CGCACGATATCTAGTGACAGAGGAGAAAGTGGAAAATGACCTCAAGGAAGCTACGGGCACAACTGGAAGCTTTGTAGAAATTAAACATAT TCAAGGAGCAAGAAATGAACTTTCAGCAGTCTAAATTTTCTAAATAACCAATAGTTGCCAATCTAAAATGGCAGAGAAGATGAAATTTGA TAAACTGAATTTTTTTTAAAAATCCATTTACCCTACAGGTTTGCATTTGTTTGCTGAAATTTACCTTTTTTTAGTTATATATATGTGTGT GTGTGTGTGTAATTTCTGCCAATAAATTCTAAATTACAAAGGTAAGAGAAAACCTAGTACATTACTAAATATATAAAGTATATGTTCTGA TTATGTATACTTGTTCTAGTGTCAAGTCTTTTTAAGTGGGTTTTTAAAAGTTTGTTATTGGACTTGAATGGATTTTTGAGACTAGGTTAA TTATTTTTGAGGTCTTATCCTAAAAGGCATCTAAGGTACATGAATGGAGTATGGTGATTTTATAACATTTTTTATCAGAATGGAAAAAGA ACTGTTTAAAAGTTTGATACTTTTAAATAGTTGGTTTTTTTGCTTACTCTGGTAATGATTTTCTACAAATACATAATAAATTGTTTTTTT GAGTCTATATTCTGTATGCAGTTGAATATCCATTACTTATTCTGCTGTGCTTTAATAGAATGGAATGTTTACAGGCCCTTAAAATATTAT TTTTAAAAAACCTTCTGAAGATACATACCAAAGTTTTTCCAAGAAGATTTTATAATCAATTTAATAATGTAAGGTTTATCAGATTCTATA ATAGTATAGTTATTAAGGCAATTTTATGTTAGAGACTATTTTGTAATGTAGTGAGTGGTACCTTTATAAGAAAAGTGACTGCCAATATAT TTTTATAGCTGATCTTTATAAATTCTAATGTTGAGTTTTTAATGATTATTTTAAATGTTTATATAGTTTAGTAAAATTTGCATCTCAAAG TATCATTTTTATATTATGGGACGTTTTCAGATTGGCTAATATTTGCATTGTAAATTTTGTATGCAGTTTATCTAAAATTCAAAAATACTG TCAGTACACCAGCGTTTAACATCTATATTCCAATTTGTATACAGTTTAAAATTGTACTGCAAAACTATTGTGTGCTCTTACACAGTATGC >79692_79692_3_SCN8A-ATF1_SCN8A_chr12_52184286_ENST00000545061_ATF1_chr12_51189691_ENST00000262053_length(amino acids)=1713AA_BP=1473 MLQDEKMAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDF DPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESL VKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSV FALIGLQLFMGNLRNKCVVWPINFNESYLENGTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFD TFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQE EAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDN RIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGS RSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEATTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEE SQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKL IAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGM QLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADN LAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQREADEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSV EKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEG CVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAY GFVKFFTNAWCWLDFLIVAVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNT EIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKYEDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFG GQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLVSSLSESEESQDSSDSIGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENSGV SAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQGLQTLTMTNSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQT YQIRTTPSATSLPQTVVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSN -------------------------------------------------------------- >79692_79692_4_SCN8A-ATF1_SCN8A_chr12_52184286_ENST00000545061_ATF1_chr12_51189692_ENST00000262053_length(transcript)=6521nt_BP=4455nt AGCTGACCTGTCCTGGACGCAGCATAACTAACGAAGCTGCTGCAGGATGAGAAGATGGCAGCGCGGCTGCTTGCACCACCAGGCCCTGAT AGTTTCAAGCCTTTCACCCCTGAGTCACTGGCAAACATTGAGAGGCGCATTGCTGAGAGCAAGCTCAAGAAACCACCAAAGGCCGATGGC AGTCATCGGGAGGACGATGAGGACAGCAAGCCCAAGCCAAACAGCGACCTGGAAGCAGGGAAGAGTTTGCCTTTCATCTACGGGGACATC CCCCAAGGCCTGGTTGCAGTTCCCCTGGAGGACTTTGACCCATACTATTTGACGCAGAAAACCTTTGTAGTATTAAACAGAGGGAAAACT CTCTTCAGATTTAGTGCCACGCCTGCCTTGTACATTTTAAGTCCTTTTAACCTGATAAGAAGAATAGCTATTAAAATTTTGATACATTCA GTATTTAGCATGATCATTATGTGCACTATTTTGACCAACTGTGTATTCATGACTTTTAGTAACCCTCCTGACTGGTCGAAGAATGTGGAG TACACGTTCACAGGGATTTATACATTTGAATCACTAGTGAAAATCATTGCAAGAGGTTTCTGCATAGATGGCTTTACCTTTTTACGGGAC CCATGGAACTGGTTAGATTTCAGTGTCATCATGATGGCGTATATAACAGAGTTTGTAAACCTAGGCAATGTTTCAGCTCTACGCACTTTC AGGGTACTGAGGGCTTTGAAAACTATTTCGGTAATCCCAGGCCTGAAGACAATTGTGGGTGCCCTGATTCAGTCTGTGAAGAAACTGTCA GATGTGATGATCCTGACAGTGTTCTGCCTGAGTGTTTTTGCCTTGATCGGACTGCAGCTGTTCATGGGGAACCTTCGAAACAAGTGTGTT GTGTGGCCCATAAACTTCAACGAGAGCTATCTTGAAAATGGCACCAAAGGCTTTGATTGGGAAGAGTATATCAACAATAAAACAAATTTC TACACAGTTCCTGGCATGCTGGAACCTTTACTCTGTGGGAACAGTTCTGATGCTGGGCAATGCCCAGAGGGATACCAGTGTATGAAAGCA GGAAGGAACCCCAACTATGGTTACACAAGTTTTGACACTTTTAGCTGGGCCTTCTTGGCATTATTTCGCCTTATGACCCAGGACTATTGG GAAAACTTGTATCAATTGACTTTACGAGCAGCCGGGAAAACATACATGATCTTCTTCGTCTTGGTCATCTTTGTGGGTTCTTTCTATCTG GTGAACTTGATCTTGGCTGTGGTGGCCATGGCTTATGAAGAACAGAATCAGGCAACACTGGAGGAGGCAGAACAAAAAGAGGCTGAATTT AAAGCAATGTTGGAGCAACTTAAGAAGCAACAGGAAGAGGCACAGGCTGCTGCGATGGCCACTTCAGCAGGAACTGTCTCAGAAGATGCC ATAGAGGAAGAAGGTGAAGAAGGAGGGGGCTCCCCTCGGAGCTCTTCTGAAATCTCTAAACTCAGCTCAAAGAGTGCAAAGGAAAGACGT AACAGGAGAAAGAAGAGGAAGCAAAAGGAACTCTCTGAAGGAGAGGAGAAAGGGGATCCCGAGAAGGTGTTTAAGTCAGAGTCAGAAGAT GGCATGAGAAGGAAGGCCTTTCGGCTGCCAGACAACAGAATAGGGAGGAAATTTTCCATCATGAATCAGTCACTGCTCAGCATCCCAGGC TCGCCCTTCCTCTCCCGCCACAACAGCAAGAGCAGCATCTTCAGTTTCAGGGGACCTGGGCGGTTCCGAGACCCGGGCTCCGAGAATGAG TTCGCGGATGACGAGCACAGCACGGTGGAGGAGAGCGAGGGCCGCCGGGACTCCCTCTTCATCCCCATCCGGGCCCGCGAGCGCCGGAGC AGCTACAGCGGCTACAGCGGCTACAGCCAGGGCAGCCGCTCCTCGCGCATCTTCCCCAGCCTGCGGCGCAGCGTGAAGCGCAACAGCACG GTGGACTGCAACGGCGTGGTGTCCCTCATCGGCGGCCCCGGCTCCCACATCGGCGGGCGTCTCCTGCCAGAGGCTACAACTGAGGTGGAA ATTAAGAAGAAAGGCCCTGGATCTCTTTTAGTTTCCATGGACCAATTAGCCTCCTACGGGCGGAAGGACAGAATCAACAGTATAATGAGT GTTGTTACAAATACACTAGTAGAAGAACTGGAAGAGTCTCAGAGAAAGTGCCCGCCATGCTGGTATAAATTTGCCAACACTTTCCTCATC TGGGAGTGCCACCCCTACTGGATAAAACTGAAAGAGATTGTGAACTTGATAGTTATGGACCCTTTTGTGGATTTAGCCATCACCATCTGC ATCGTCCTGAATACACTGTTTATGGCAATGGAGCACCATCCTATGACACCACAATTTGAACATGTCTTGGCTGTAGGAAATCTGGTTTTC ACTGGAATTTTCACAGCGGAAATGTTCCTGAAGCTCATAGCCATGGATCCCTACTATTATTTCCAAGAAGGTTGGAACATTTTTGACGGA TTTATTGTCTCCCTCAGTTTAATGGAACTGAGTCTAGCAGACGTGGAGGGGCTTTCAGTGCTGCGATCTTTCCGATTGCTCCGAGTCTTC AAATTGGCCAAATCCTGGCCCACCCTGAACATGCTAATCAAGATTATTGGAAATTCAGTGGGTGCCCTGGGCAACCTGACACTGGTGCTG GCCATTATTGTCTTCATCTTTGCCGTGGTGGGGATGCAACTCTTTGGAAAAAGCTACAAAGAGTGTGTCTGCAAGATCAACCAGGACTGT GAACTCCCTCGCTGGCATATGCATGACTTTTTCCATTCCTTCCTCATTGTCTTTCGAGTGTTGTGCGGGGAGTGGATTGAGACCATGTGG GACTGCATGGAAGTGGCAGGCCAGGCCATGTGCCTCATTGTCTTTATGATGGTCATGGTGATTGGCAACTTGGTGGTGCTGAACCTGTTT CTGGCCTTGCTCCTGAGCTCCTTCAGTGCAGACAACCTGGCTGCCACAGATGACGATGGGGAAATGAACAACCTCCAGATCTCAGTGATC CGTATCAAGAAGGGTGTGGCCTGGACCAAACTAAAGGTGCACGCCTTCATGCAGGCCCACTTTAAGCAGCGTGAGGCTGATGAGGTGAAG CCTCTGGATGAGTTGTATGAAAAGAAGGCCAACTGTATCGCCAATCACACCGGTGCAGACATCCACCGGAATGGTGACTTCCAGAAGAAT GGCAATGGCACAACCAGCGGCATTGGCAGCAGCGTGGAGAAGTACATCATTGATGAGGACCACATGTCCTTCATCAACAACCCCAACTTG ACTGTACGGGTACCCATTGCTGTGGGCGAGTCTGACTTTGAGAACCTCAACACAGAGGATGTTAGCAGCGAGTCGGATCCTGAAGGCAGC AAAGATAAACTAGATGACACCAGCTCCTCTGAAGGAAGCACCATTGATATCAAACCAGAAGTAGAAGAGGTCCCTGTGGAACAGCCTGAG GAATACTTGGATCCAGATGCCTGCTTCACAGAAGGTTGTGTCCAGCGGTTCAAGTGCTGCCAGGTCAACATCGAGGAAGGGCTAGGCAAG TCTTGGTGGATCCTGCGGAAAACCTGCTTCCTCATCGTGGAGCACAACTGGTTTGAGACCTTCATCATCTTCATGATTCTGCTGAGCAGT GGCGCCCTGGCCTTCGAGGACATCTACATTGAGCAGAGAAAGACCATCCGCACCATCCTGGAATATGCTGACAAAGTCTTCACCTATATC TTCATCCTGGAGATGTTGCTCAAGTGGACAGCCTATGGCTTCGTCAAGTTCTTCACCAATGCCTGGTGTTGGCTGGACTTCCTCATTGTG GCTGTGGTGGTGAATGCCTTGGTGGGCGCCATCCCCTCCATCATGAATGTGCTGCTGGTGTGTCTCATCTTCTGGCTGATTTTCAGCATC ATGGGAGTTAACTTGTTTGCGGGAAAGTACCACTACTGCTTTAATGAGACTTCTGAAATCCGATTTGAAATTGAAGATGTCAACAATAAA ACTGAATGTGAAAAGCTTATGGAGGGGAACAATACAGAGATCAGATGGAAGAACGTGAAGATCAACTTTGACAATGTTGGGGCAGGATAC CTGGCCCTTCTTCAAGTAGCAACCTTCAAAGGCTGGATGGACATCATGTATGCAGCTGTAGATTCCCGGAAGCCTGATGAGCAGCCTAAG TATGAGGACAATATCTACATGTACATCTATTTTGTCATCTTCATCATCTTCGGCTCCTTCTTCACCCTGAACCTGTTCATTGGTGTCATC ATTGATAACTTCAATCAACAAAAGAAAAAGTTCGGAGGTCAGGACATCTTCATGACCGAAGAACAGAAGAAGTACTACAATGCCATGAAA AAGCTGGGCTCAAAGAAGCCACAGAAACCTATTCCCCGCCCCTTGGTATCATCTTTATCAGAAAGTGAGGAGTCCCAGGACTCATCCGAC AGCATAGGCTCCTCACAGAAAGCCCACGGGATCCTAGCACGGCGCCCATCTTACAGAAAAATTTTGAAAGACTTATCTTCTGAAGATACA CGGGGCAGAAAAGGAGACGGAGAAAATTCTGGAGTTTCTGCTGCTGTCACTTCTATGTCTGTTCCAACTCCCATCTATCAGACTAGCAGC GGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATG ACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAG GTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATG ACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCT GCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATA GAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGGACATGCATAAAAATT AAATGGATTTCCTAGTGGAGTTTTATAAATTAAAAGGTCAAAACTGAAGCTTTTTATTTAGGCTTTTCCAAATCAAGGATAAATATCTTA CGCACGATATCTAGTGACAGAGGAGAAAGTGGAAAATGACCTCAAGGAAGCTACGGGCACAACTGGAAGCTTTGTAGAAATTAAACATAT TCAAGGAGCAAGAAATGAACTTTCAGCAGTCTAAATTTTCTAAATAACCAATAGTTGCCAATCTAAAATGGCAGAGAAGATGAAATTTGA TAAACTGAATTTTTTTTAAAAATCCATTTACCCTACAGGTTTGCATTTGTTTGCTGAAATTTACCTTTTTTTAGTTATATATATGTGTGT GTGTGTGTGTAATTTCTGCCAATAAATTCTAAATTACAAAGGTAAGAGAAAACCTAGTACATTACTAAATATATAAAGTATATGTTCTGA TTATGTATACTTGTTCTAGTGTCAAGTCTTTTTAAGTGGGTTTTTAAAAGTTTGTTATTGGACTTGAATGGATTTTTGAGACTAGGTTAA TTATTTTTGAGGTCTTATCCTAAAAGGCATCTAAGGTACATGAATGGAGTATGGTGATTTTATAACATTTTTTATCAGAATGGAAAAAGA ACTGTTTAAAAGTTTGATACTTTTAAATAGTTGGTTTTTTTGCTTACTCTGGTAATGATTTTCTACAAATACATAATAAATTGTTTTTTT GAGTCTATATTCTGTATGCAGTTGAATATCCATTACTTATTCTGCTGTGCTTTAATAGAATGGAATGTTTACAGGCCCTTAAAATATTAT TTTTAAAAAACCTTCTGAAGATACATACCAAAGTTTTTCCAAGAAGATTTTATAATCAATTTAATAATGTAAGGTTTATCAGATTCTATA ATAGTATAGTTATTAAGGCAATTTTATGTTAGAGACTATTTTGTAATGTAGTGAGTGGTACCTTTATAAGAAAAGTGACTGCCAATATAT TTTTATAGCTGATCTTTATAAATTCTAATGTTGAGTTTTTAATGATTATTTTAAATGTTTATATAGTTTAGTAAAATTTGCATCTCAAAG TATCATTTTTATATTATGGGACGTTTTCAGATTGGCTAATATTTGCATTGTAAATTTTGTATGCAGTTTATCTAAAATTCAAAAATACTG TCAGTACACCAGCGTTTAACATCTATATTCCAATTTGTATACAGTTTAAAATTGTACTGCAAAACTATTGTGTGCTCTTACACAGTATGC >79692_79692_4_SCN8A-ATF1_SCN8A_chr12_52184286_ENST00000545061_ATF1_chr12_51189692_ENST00000262053_length(amino acids)=1713AA_BP=1473 MLQDEKMAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDF DPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESL VKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSV FALIGLQLFMGNLRNKCVVWPINFNESYLENGTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFD TFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQE EAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDN RIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGS RSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEATTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEE SQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKL IAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGM QLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADN LAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQREADEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSV EKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEG CVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAY GFVKFFTNAWCWLDFLIVAVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNT EIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKYEDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFG GQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLVSSLSESEESQDSSDSIGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENSGV SAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQGLQTLTMTNSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQT YQIRTTPSATSLPQTVVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSN -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SCN8A-ATF1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SCN8A-ATF1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SCN8A-ATF1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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