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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SDHA-VDAC3 (FusionGDB2 ID:79911)

Fusion Gene Summary for SDHA-VDAC3

Fusion gene summary

Fusion gene information	Fusion gene name: SDHA-VDAC3
	Fusion gene ID: 79911
		Hgene	Tgene
	Gene symbol	SDHA	VDAC3
	Gene ID	6389	7419
	Gene name	succinate dehydrogenase complex flavoprotein subunit A	voltage dependent anion channel 3
	Synonyms	CMD1GG\|FP\|PGL5\|SDH1\|SDH2\|SDHF	HD-VDAC3\|VDAC-3
	Cytomap	5p15.33	8p11.21
	Type of gene	protein-coding	protein-coding
	Description	succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialflavoprotein subunit of complex IIsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)	voltage-dependent anion-selective channel protein 3outer mitochondrial membrane protein porin 3
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000264932, ENST00000504309, ENST00000510361, ENST00000507522,	ENST00000022615, ENST00000392935, ENST00000521158, ENST00000522572,
Fusion gene scores	* DoF score	10 X 7 X 6=420	8 X 8 X 6=384
	# samples	11	8
	** MAII score	log2(11/420*10)=-1.93288580414146 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(8/384*10)=-2.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SDHA [Title/Abstract] AND VDAC3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SDHA(233760)-VDAC3(42259306), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	SDHA	GO:0006105	succinate metabolic process	7550341
Hgene	SDHA	GO:0022904	respiratory electron transport chain	7550341
Hgene	SDHA	GO:0055114	oxidation-reduction process	7550341

Fusion gene breakpoints across SDHA (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across VDAC3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-BR-A4PD-01A	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+

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Fusion Gene ORF analysis for SDHA-VDAC3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000264932	ENST00000022615	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
In-frame	ENST00000264932	ENST00000392935	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
In-frame	ENST00000264932	ENST00000521158	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
In-frame	ENST00000264932	ENST00000522572	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
In-frame	ENST00000504309	ENST00000022615	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
In-frame	ENST00000504309	ENST00000392935	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
In-frame	ENST00000504309	ENST00000521158	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
In-frame	ENST00000504309	ENST00000522572	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
In-frame	ENST00000510361	ENST00000022615	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
In-frame	ENST00000510361	ENST00000392935	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
In-frame	ENST00000510361	ENST00000521158	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
In-frame	ENST00000510361	ENST00000522572	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
intron-3CDS	ENST00000507522	ENST00000022615	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
intron-3CDS	ENST00000507522	ENST00000392935	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
intron-3CDS	ENST00000507522	ENST00000521158	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+
intron-3CDS	ENST00000507522	ENST00000522572	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000264932	SDHA	chr5	233760	+	ENST00000392935	VDAC3	chr8	42259306	+	2139	1179	73	1707	544
ENST00000264932	SDHA	chr5	233760	+	ENST00000522572	VDAC3	chr8	42259306	+	1545	1179	73	1257	394
ENST00000264932	SDHA	chr5	233760	+	ENST00000521158	VDAC3	chr8	42259306	+	1734	1179	73	1707	544
ENST00000264932	SDHA	chr5	233760	+	ENST00000022615	VDAC3	chr8	42259306	+	2143	1179	73	1707	544
ENST00000504309	SDHA	chr5	233760	+	ENST00000392935	VDAC3	chr8	42259306	+	2077	1117	11	1645	544
ENST00000504309	SDHA	chr5	233760	+	ENST00000522572	VDAC3	chr8	42259306	+	1483	1117	11	1195	394
ENST00000504309	SDHA	chr5	233760	+	ENST00000521158	VDAC3	chr8	42259306	+	1672	1117	11	1645	544
ENST00000504309	SDHA	chr5	233760	+	ENST00000022615	VDAC3	chr8	42259306	+	2081	1117	11	1645	544
ENST00000510361	SDHA	chr5	233760	+	ENST00000392935	VDAC3	chr8	42259306	+	1918	958	38	1486	482
ENST00000510361	SDHA	chr5	233760	+	ENST00000522572	VDAC3	chr8	42259306	+	1324	958	38	1036	332
ENST00000510361	SDHA	chr5	233760	+	ENST00000521158	VDAC3	chr8	42259306	+	1513	958	38	1486	482
ENST00000510361	SDHA	chr5	233760	+	ENST00000022615	VDAC3	chr8	42259306	+	1922	958	38	1486	482

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000264932	ENST00000392935	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.002079826	0.9979202
ENST00000264932	ENST00000522572	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.004133452	0.99586654
ENST00000264932	ENST00000521158	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.005575927	0.99442405
ENST00000264932	ENST00000022615	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.002028579	0.99797136
ENST00000504309	ENST00000392935	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.002041751	0.9979583
ENST00000504309	ENST00000522572	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.004306776	0.99569327
ENST00000504309	ENST00000521158	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.005897081	0.9941029
ENST00000504309	ENST00000022615	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.001996996	0.99800295
ENST00000510361	ENST00000392935	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.001247383	0.9987526
ENST00000510361	ENST00000522572	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.00242886	0.9975712
ENST00000510361	ENST00000521158	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.003828839	0.9961712
ENST00000510361	ENST00000022615	SDHA	chr5	233760	+	VDAC3	chr8	42259306	+	0.001209491	0.99879056

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Fusion Genomic Features for SDHA-VDAC3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
SDHA	chr5	233760	+	VDAC3	chr8	42259305	+	0.000163134	0.9998368
SDHA	chr5	233760	+	VDAC3	chr8	42259305	+	0.000163134	0.9998368

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SDHA-VDAC3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:233760/chr8:42259306)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SDHA

chr5:233760

chr8:42259306

ENST00000264932

68_73

354

665.0

Nucleotide binding

FAD

Hgene

SDHA

chr5:233760

chr8:42259306

ENST00000264932

91_106

354

665.0

Nucleotide binding

FAD

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

242_244

107

284.0

Nucleotide binding

NAD

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

260_264

107

284.0

Nucleotide binding

NAD

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

242_244

108

285.0

Nucleotide binding

NAD

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

260_264

108

285.0

Nucleotide binding

NAD

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

111_120

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

123_130

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

137_145

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

150_158

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

163_175

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

178_185

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

189_198

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

202_211

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

218_227

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

231_238

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

242_251

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

254_263

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

273_282

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

111_120

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

123_130

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

137_145

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

150_158

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

163_175

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

178_185

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

189_198

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

202_211

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

218_227

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

231_238

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

242_251

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

254_263

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

273_282

108

285.0

Transmembrane

Beta stranded

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SDHA

chr5:233760

chr8:42259306

ENST00000264932

456_457

354

665.0

Nucleotide binding

FAD

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

26_35

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

39_47

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

54_64

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

69_76

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

80_89

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000022615

95_104

107

284.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

26_35

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

39_47

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

54_64

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

69_76

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

80_89

108

285.0

Transmembrane

Beta stranded

Tgene

VDAC3

chr5:233760

chr8:42259306

ENST00000521158

95_104

108

285.0

Transmembrane

Beta stranded

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Fusion Gene Sequence for SDHA-VDAC3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>79911_79911_1_SDHA-VDAC3_SDHA_chr5_233760_ENST00000264932_VDAC3_chr8_42259306_ENST00000022615_length(transcript)=2143nt_BP=1179nt
TCCGGCGTGGTGCGCAGGCGCGGTATCCCCCCTCCCCCGCCAGCTCGACCCCGGTGTGGTGCGCAGGCGCAGTCTGCGCAGGGACTGGCG
GGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCGCTCGGCGCCTGGCGCTGGCCAAGGCGTG
GCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGGCATCTGCTAAAGTTTCAGATTCCATTTC
TGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAGGCTTGCGAGCTGCATTTGGCCTTTCTGA
GGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAGCACAGGGAGGAATCAATGCTGCTCTGGG
GAACATGGAGGAGGACAACTGGAGGTGGCATTTCTACGACACCGTGAAGGGCTCCGACTGGCTGGGGGACCAGGATGCCATCCACTACAT
GACGGAGCAGGCCCCCGCCGCCGTGGTCGAGCTAGAAAATTATGGCATGCCGTTTAGCAGAACTGAAGATGGGAAGATTTATCAGCGTGC
ATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGGCCCATCGGTGCTGCTGTGTGGCTGATCGGACTGGCCACTCGCTATTGCA
CACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATTTTGTGGAGTATTTTGCCTTGGATCTCCTGATGGAGAATGGGGAGTGCCG
TGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATCGCATAAGAGCAAAGAACACTGTTGTTGCCACAGGAGGCTACGGGCGCAC
CTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACGGCACGGCCATGATCACCAGGGCAGGCCTTCCTTGCCAGGACCTAGAGTT
TGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTCTCATTACGGAAGGATGTCGTGGAGAGGGAGGCATTCTCATTAACAGTCA
AGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGGACCTGGCGTCTAGAGATGTGGTGTCTCGGTCCATGACTCTGGAGATCCG
AGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGGGATTGTTTTAGTGTTGGCAGTAATGTTGATATAGATTTTTCTGG
ACCAACCATCTATGGCTGGGCTGTGTTGGCCTTCGAAGGGTGGCTTGCTGGCTATCAGATGAGTTTTGACACAGCCAAATCCAAACTGTC
ACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCCAGCTGCACACACATGTGAACGATGGCACTGAATTTGGAGGTTCTATCTA
CCAGAAGGTGAATGAGAAGATTGAAACATCCATAAACCTTGCTTGGACAGCTGGGAGTAACAACACCCGTTTTGGCATTGCTGCTAAGTA
CATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATAATGCCAGCCTGATTGGACTGGGTTATACTCAGACCCTTCGACCAGGAGT
CAAATTGACTTTATCAGCTTTAATCGATGGGAAGAACTTCAGTGCAGGAGGTCACAAGGTTGGCTTGGGATTTGAACTGGAAGCTTAATG
TGGTTTGAGGAAAGCATCAGATTTGTCCCTGGAAGTGAAGAGAAATGAACCCACTATGTTTTGGCCTTAAAATTCTTCTGTGAAATTTCA
AAAGTGTGAACTTTTTATTCTTCCAAAGAATTGTAATCCTCCCCACACTGAAGTCTAGGGGTTGCGAATCCCTCCTGAGGGAGATGCTTG
AAGGCATGCCTGGAAGTTGTCATGTTTGTGCCACGTTTCAGTTCAGTTCTGAAGTGTTATTAAATGTGTTCCTCAGCGACAGTGTAGCGT
CATGTTAGAGGAGACGATCTGACCCACCAGTTTGTACATCACGTCCTGCATGTCCCACACCATTTTTTCATGACCTTGTAATATACTGGT

>79911_79911_1_SDHA-VDAC3_SDHA_chr5_233760_ENST00000264932_VDAC3_chr8_42259306_ENST00000022615_length(amino acids)=544AA_BP=368
MRRDWRDCAAATADMSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRA
AFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDG
KIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVAT
GGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRS
MTLEIREGRKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTE
FGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGF

--------------------------------------------------------------
>79911_79911_2_SDHA-VDAC3_SDHA_chr5_233760_ENST00000264932_VDAC3_chr8_42259306_ENST00000392935_length(transcript)=2139nt_BP=1179nt
TCCGGCGTGGTGCGCAGGCGCGGTATCCCCCCTCCCCCGCCAGCTCGACCCCGGTGTGGTGCGCAGGCGCAGTCTGCGCAGGGACTGGCG
GGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCGCTCGGCGCCTGGCGCTGGCCAAGGCGTG
GCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGGCATCTGCTAAAGTTTCAGATTCCATTTC
TGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAGGCTTGCGAGCTGCATTTGGCCTTTCTGA
GGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAGCACAGGGAGGAATCAATGCTGCTCTGGG
GAACATGGAGGAGGACAACTGGAGGTGGCATTTCTACGACACCGTGAAGGGCTCCGACTGGCTGGGGGACCAGGATGCCATCCACTACAT
GACGGAGCAGGCCCCCGCCGCCGTGGTCGAGCTAGAAAATTATGGCATGCCGTTTAGCAGAACTGAAGATGGGAAGATTTATCAGCGTGC
ATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGGCCCATCGGTGCTGCTGTGTGGCTGATCGGACTGGCCACTCGCTATTGCA
CACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATTTTGTGGAGTATTTTGCCTTGGATCTCCTGATGGAGAATGGGGAGTGCCG
TGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATCGCATAAGAGCAAAGAACACTGTTGTTGCCACAGGAGGCTACGGGCGCAC
CTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACGGCACGGCCATGATCACCAGGGCAGGCCTTCCTTGCCAGGACCTAGAGTT
TGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTCTCATTACGGAAGGATGTCGTGGAGAGGGAGGCATTCTCATTAACAGTCA
AGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGGACCTGGCGTCTAGAGATGTGGTGTCTCGGTCCATGACTCTGGAGATCCG
AGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGGGATTGTTTTAGTGTTGGCAGTAATGTTGATATAGATTTTTCTGG
ACCAACCATCTATGGCTGGGCTGTGTTGGCCTTCGAAGGGTGGCTTGCTGGCTATCAGATGAGTTTTGACACAGCCAAATCCAAACTGTC
ACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCCAGCTGCACACACATGTGAACGATGGCACTGAATTTGGAGGTTCTATCTA
CCAGAAGGTGAATGAGAAGATTGAAACATCCATAAACCTTGCTTGGACAGCTGGGAGTAACAACACCCGTTTTGGCATTGCTGCTAAGTA
CATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATAATGCCAGCCTGATTGGACTGGGTTATACTCAGACCCTTCGACCAGGAGT
CAAATTGACTTTATCAGCTTTAATCGATGGGAAGAACTTCAGTGCAGGAGGTCACAAGGTTGGCTTGGGATTTGAACTGGAAGCTTAATG
TGGTTTGAGGAAAGCATCAGATTTGTCCCTGGAAGTGAAGAGAAATGAACCCACTATGTTTTGGCCTTAAAATTCTTCTGTGAAATTTCA
AAAGTGTGAACTTTTTATTCTTCCAAAGAATTGTAATCCTCCCCACACTGAAGTCTAGGGGTTGCGAATCCCTCCTGAGGGAGATGCTTG
AAGGCATGCCTGGAAGTTGTCATGTTTGTGCCACGTTTCAGTTCAGTTCTGAAGTGTTATTAAATGTGTTCCTCAGCGACAGTGTAGCGT
CATGTTAGAGGAGACGATCTGACCCACCAGTTTGTACATCACGTCCTGCATGTCCCACACCATTTTTTCATGACCTTGTAATATACTGGT

>79911_79911_2_SDHA-VDAC3_SDHA_chr5_233760_ENST00000264932_VDAC3_chr8_42259306_ENST00000392935_length(amino acids)=544AA_BP=368
MRRDWRDCAAATADMSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRA
AFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDG
KIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVAT
GGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRS
MTLEIREGRKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTE
FGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGF

--------------------------------------------------------------
>79911_79911_3_SDHA-VDAC3_SDHA_chr5_233760_ENST00000264932_VDAC3_chr8_42259306_ENST00000521158_length(transcript)=1734nt_BP=1179nt
TCCGGCGTGGTGCGCAGGCGCGGTATCCCCCCTCCCCCGCCAGCTCGACCCCGGTGTGGTGCGCAGGCGCAGTCTGCGCAGGGACTGGCG
GGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCGCTCGGCGCCTGGCGCTGGCCAAGGCGTG
GCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGGCATCTGCTAAAGTTTCAGATTCCATTTC
TGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAGGCTTGCGAGCTGCATTTGGCCTTTCTGA
GGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAGCACAGGGAGGAATCAATGCTGCTCTGGG
GAACATGGAGGAGGACAACTGGAGGTGGCATTTCTACGACACCGTGAAGGGCTCCGACTGGCTGGGGGACCAGGATGCCATCCACTACAT
GACGGAGCAGGCCCCCGCCGCCGTGGTCGAGCTAGAAAATTATGGCATGCCGTTTAGCAGAACTGAAGATGGGAAGATTTATCAGCGTGC
ATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGGCCCATCGGTGCTGCTGTGTGGCTGATCGGACTGGCCACTCGCTATTGCA
CACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATTTTGTGGAGTATTTTGCCTTGGATCTCCTGATGGAGAATGGGGAGTGCCG
TGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATCGCATAAGAGCAAAGAACACTGTTGTTGCCACAGGAGGCTACGGGCGCAC
CTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACGGCACGGCCATGATCACCAGGGCAGGCCTTCCTTGCCAGGACCTAGAGTT
TGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTCTCATTACGGAAGGATGTCGTGGAGAGGGAGGCATTCTCATTAACAGTCA
AGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGGACCTGGCGTCTAGAGATGTGGTGTCTCGGTCCATGACTCTGGAGATCCG
AGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGGGATTGTTTTAGTGTTGGCAGTAATGTTGATATAGATTTTTCTGG
ACCAACCATCTATGGCTGGGCTGTGTTGGCCTTCGAAGGGTGGCTTGCTGGCTATCAGATGAGTTTTGACACAGCCAAATCCAAACTGTC
ACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCCAGCTGCACACACATGTGAACGATGGCACTGAATTTGGAGGTTCTATCTA
CCAGAAGGTGAATGAGAAGATTGAAACATCCATAAACCTTGCTTGGACAGCTGGGAGTAACAACACCCGTTTTGGCATTGCTGCTAAGTA
CATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATAATGCCAGCCTGATTGGACTGGGTTATACTCAGACCCTTCGACCAGGAGT
CAAATTGACTTTATCAGCTTTAATCGATGGGAAGAACTTCAGTGCAGGAGGTCACAAGGTTGGCTTGGGATTTGAACTGGAAGCTTAATG

>79911_79911_3_SDHA-VDAC3_SDHA_chr5_233760_ENST00000264932_VDAC3_chr8_42259306_ENST00000521158_length(amino acids)=544AA_BP=368
MRRDWRDCAAATADMSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRA
AFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDG
KIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVAT
GGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRS
MTLEIREGRKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTE
FGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGF

--------------------------------------------------------------
>79911_79911_4_SDHA-VDAC3_SDHA_chr5_233760_ENST00000264932_VDAC3_chr8_42259306_ENST00000522572_length(transcript)=1545nt_BP=1179nt
TCCGGCGTGGTGCGCAGGCGCGGTATCCCCCCTCCCCCGCCAGCTCGACCCCGGTGTGGTGCGCAGGCGCAGTCTGCGCAGGGACTGGCG
GGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCGCTCGGCGCCTGGCGCTGGCCAAGGCGTG
GCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGGCATCTGCTAAAGTTTCAGATTCCATTTC
TGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAGGCTTGCGAGCTGCATTTGGCCTTTCTGA
GGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAGCACAGGGAGGAATCAATGCTGCTCTGGG
GAACATGGAGGAGGACAACTGGAGGTGGCATTTCTACGACACCGTGAAGGGCTCCGACTGGCTGGGGGACCAGGATGCCATCCACTACAT
GACGGAGCAGGCCCCCGCCGCCGTGGTCGAGCTAGAAAATTATGGCATGCCGTTTAGCAGAACTGAAGATGGGAAGATTTATCAGCGTGC
ATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGGCCCATCGGTGCTGCTGTGTGGCTGATCGGACTGGCCACTCGCTATTGCA
CACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATTTTGTGGAGTATTTTGCCTTGGATCTCCTGATGGAGAATGGGGAGTGCCG
TGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATCGCATAAGAGCAAAGAACACTGTTGTTGCCACAGGAGGCTACGGGCGCAC
CTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACGGCACGGCCATGATCACCAGGGCAGGCCTTCCTTGCCAGGACCTAGAGTT
TGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTCTCATTACGGAAGGATGTCGTGGAGAGGGAGGCATTCTCATTAACAGTCA
AGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGGACCTGGCGTCTAGAGATGTGGTGTCTCGGTCCATGACTCTGGAGATCCG
AGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGGGATTGTTTTAGTGTTGGCTTGGGATTTGAACTGGAAGCTTAATG
TGGTTTGAGGAAAGCATCAGATTTGTCCCTGGAAGTGAAGAGAAATGAACCCACTATGTTTTGGCCTTAAAATTCTTCTGTGAAATTTCA
AAAGTGTGAACTTTTTATTCTTCCAAAGAATTGTAATCCTCCCCACACTGAAGTCTAGGGGTTGCGAATCCCTCCTGAGGGAGATGCTTG
AAGGCATGCCTGGAAGTTGTCATGTTTGTGCCACGTTTCAGTTCAGTTCTGAAGTGTTATTAAATGTGTTCCTCAGCGACAGTGTAGCGT

>79911_79911_4_SDHA-VDAC3_SDHA_chr5_233760_ENST00000264932_VDAC3_chr8_42259306_ENST00000522572_length(amino acids)=394AA_BP=368
MRRDWRDCAAATADMSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRA
AFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDG
KIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVAT
GGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRS

--------------------------------------------------------------
>79911_79911_5_SDHA-VDAC3_SDHA_chr5_233760_ENST00000504309_VDAC3_chr8_42259306_ENST00000022615_length(transcript)=2081nt_BP=1117nt
GCAGGCGCAGTCTGCGCAGGGACTGGCGGGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCG
CTCGGCGCCTGGCGCTGGCCAAGGCGTGGCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGG
CATCTGCTAAAGTTTCAGATTCCATTTCTGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAG
GCTTGCGAGCTGCATTTGGCCTTTCTGAGGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAG
CACAGGGAGGAATCAATGCTGCTCTGGGGAACATGGAGGAGGACAACTGGAGGTGGCATTTCTACGACACCGTGAAGGGCTCCGACTGGC
TGGGGGACCAGGATGCCATCCACTACATGACGGAGCAGGCCCCCGCCGCCGTGGTCGAGCTAGAAAATTATGGCATGCCGTTTAGCAGAA
CTGAAGATGGGAAGATTTATCAGCGTGCATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGGCCCATCGGTGCTGCTGTGTGG
CTGATCGGACTGGCCACTCGCTATTGCACACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATTTTGTGGAGTATTTTGCCTTGG
ATCTCCTGATGGAGAATGGGGAGTGCCGTGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATCGCATAAGAGCAAAGAACACTG
TTGTTGCCACAGGAGGCTACGGGCGCACCTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACGGCACGGCCATGATCACCAGGG
CAGGCCTTCCTTGCCAGGACCTAGAGTTTGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTCTCATTACGGAAGGATGTCGTG
GAGAGGGAGGCATTCTCATTAACAGTCAAGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGGACCTGGCGTCTAGAGATGTGG
TGTCTCGGTCCATGACTCTGGAGATCCGAGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGGGATTGTTTTAGTGTTG
GCAGTAATGTTGATATAGATTTTTCTGGACCAACCATCTATGGCTGGGCTGTGTTGGCCTTCGAAGGGTGGCTTGCTGGCTATCAGATGA
GTTTTGACACAGCCAAATCCAAACTGTCACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCCAGCTGCACACACATGTGAACG
ATGGCACTGAATTTGGAGGTTCTATCTACCAGAAGGTGAATGAGAAGATTGAAACATCCATAAACCTTGCTTGGACAGCTGGGAGTAACA
ACACCCGTTTTGGCATTGCTGCTAAGTACATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATAATGCCAGCCTGATTGGACTGG
GTTATACTCAGACCCTTCGACCAGGAGTCAAATTGACTTTATCAGCTTTAATCGATGGGAAGAACTTCAGTGCAGGAGGTCACAAGGTTG
GCTTGGGATTTGAACTGGAAGCTTAATGTGGTTTGAGGAAAGCATCAGATTTGTCCCTGGAAGTGAAGAGAAATGAACCCACTATGTTTT
GGCCTTAAAATTCTTCTGTGAAATTTCAAAAGTGTGAACTTTTTATTCTTCCAAAGAATTGTAATCCTCCCCACACTGAAGTCTAGGGGT
TGCGAATCCCTCCTGAGGGAGATGCTTGAAGGCATGCCTGGAAGTTGTCATGTTTGTGCCACGTTTCAGTTCAGTTCTGAAGTGTTATTA
AATGTGTTCCTCAGCGACAGTGTAGCGTCATGTTAGAGGAGACGATCTGACCCACCAGTTTGTACATCACGTCCTGCATGTCCCACACCA
TTTTTTCATGACCTTGTAATATACTGGTCTCTGTGCTATAGTGGAATCTTTGGTTTTGCATCATAGTAAAATAAAATAAACCCATCACAT

>79911_79911_5_SDHA-VDAC3_SDHA_chr5_233760_ENST00000504309_VDAC3_chr8_42259306_ENST00000022615_length(amino acids)=544AA_BP=368
MRRDWRDCAAATADMSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRA
AFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDG
KIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVAT
GGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRS
MTLEIREGRKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTE
FGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGF

--------------------------------------------------------------
>79911_79911_6_SDHA-VDAC3_SDHA_chr5_233760_ENST00000504309_VDAC3_chr8_42259306_ENST00000392935_length(transcript)=2077nt_BP=1117nt
GCAGGCGCAGTCTGCGCAGGGACTGGCGGGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCG
CTCGGCGCCTGGCGCTGGCCAAGGCGTGGCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGG
CATCTGCTAAAGTTTCAGATTCCATTTCTGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAG
GCTTGCGAGCTGCATTTGGCCTTTCTGAGGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAG
CACAGGGAGGAATCAATGCTGCTCTGGGGAACATGGAGGAGGACAACTGGAGGTGGCATTTCTACGACACCGTGAAGGGCTCCGACTGGC
TGGGGGACCAGGATGCCATCCACTACATGACGGAGCAGGCCCCCGCCGCCGTGGTCGAGCTAGAAAATTATGGCATGCCGTTTAGCAGAA
CTGAAGATGGGAAGATTTATCAGCGTGCATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGGCCCATCGGTGCTGCTGTGTGG
CTGATCGGACTGGCCACTCGCTATTGCACACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATTTTGTGGAGTATTTTGCCTTGG
ATCTCCTGATGGAGAATGGGGAGTGCCGTGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATCGCATAAGAGCAAAGAACACTG
TTGTTGCCACAGGAGGCTACGGGCGCACCTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACGGCACGGCCATGATCACCAGGG
CAGGCCTTCCTTGCCAGGACCTAGAGTTTGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTCTCATTACGGAAGGATGTCGTG
GAGAGGGAGGCATTCTCATTAACAGTCAAGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGGACCTGGCGTCTAGAGATGTGG
TGTCTCGGTCCATGACTCTGGAGATCCGAGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGGGATTGTTTTAGTGTTG
GCAGTAATGTTGATATAGATTTTTCTGGACCAACCATCTATGGCTGGGCTGTGTTGGCCTTCGAAGGGTGGCTTGCTGGCTATCAGATGA
GTTTTGACACAGCCAAATCCAAACTGTCACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCCAGCTGCACACACATGTGAACG
ATGGCACTGAATTTGGAGGTTCTATCTACCAGAAGGTGAATGAGAAGATTGAAACATCCATAAACCTTGCTTGGACAGCTGGGAGTAACA
ACACCCGTTTTGGCATTGCTGCTAAGTACATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATAATGCCAGCCTGATTGGACTGG
GTTATACTCAGACCCTTCGACCAGGAGTCAAATTGACTTTATCAGCTTTAATCGATGGGAAGAACTTCAGTGCAGGAGGTCACAAGGTTG
GCTTGGGATTTGAACTGGAAGCTTAATGTGGTTTGAGGAAAGCATCAGATTTGTCCCTGGAAGTGAAGAGAAATGAACCCACTATGTTTT
GGCCTTAAAATTCTTCTGTGAAATTTCAAAAGTGTGAACTTTTTATTCTTCCAAAGAATTGTAATCCTCCCCACACTGAAGTCTAGGGGT
TGCGAATCCCTCCTGAGGGAGATGCTTGAAGGCATGCCTGGAAGTTGTCATGTTTGTGCCACGTTTCAGTTCAGTTCTGAAGTGTTATTA
AATGTGTTCCTCAGCGACAGTGTAGCGTCATGTTAGAGGAGACGATCTGACCCACCAGTTTGTACATCACGTCCTGCATGTCCCACACCA
TTTTTTCATGACCTTGTAATATACTGGTCTCTGTGCTATAGTGGAATCTTTGGTTTTGCATCATAGTAAAATAAAATAAACCCATCACAT

>79911_79911_6_SDHA-VDAC3_SDHA_chr5_233760_ENST00000504309_VDAC3_chr8_42259306_ENST00000392935_length(amino acids)=544AA_BP=368
MRRDWRDCAAATADMSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRA
AFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDG
KIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVAT
GGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRS
MTLEIREGRKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTE
FGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGF

--------------------------------------------------------------
>79911_79911_7_SDHA-VDAC3_SDHA_chr5_233760_ENST00000504309_VDAC3_chr8_42259306_ENST00000521158_length(transcript)=1672nt_BP=1117nt
GCAGGCGCAGTCTGCGCAGGGACTGGCGGGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCG
CTCGGCGCCTGGCGCTGGCCAAGGCGTGGCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGG
CATCTGCTAAAGTTTCAGATTCCATTTCTGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAG
GCTTGCGAGCTGCATTTGGCCTTTCTGAGGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAG
CACAGGGAGGAATCAATGCTGCTCTGGGGAACATGGAGGAGGACAACTGGAGGTGGCATTTCTACGACACCGTGAAGGGCTCCGACTGGC
TGGGGGACCAGGATGCCATCCACTACATGACGGAGCAGGCCCCCGCCGCCGTGGTCGAGCTAGAAAATTATGGCATGCCGTTTAGCAGAA
CTGAAGATGGGAAGATTTATCAGCGTGCATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGGCCCATCGGTGCTGCTGTGTGG
CTGATCGGACTGGCCACTCGCTATTGCACACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATTTTGTGGAGTATTTTGCCTTGG
ATCTCCTGATGGAGAATGGGGAGTGCCGTGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATCGCATAAGAGCAAAGAACACTG
TTGTTGCCACAGGAGGCTACGGGCGCACCTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACGGCACGGCCATGATCACCAGGG
CAGGCCTTCCTTGCCAGGACCTAGAGTTTGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTCTCATTACGGAAGGATGTCGTG
GAGAGGGAGGCATTCTCATTAACAGTCAAGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGGACCTGGCGTCTAGAGATGTGG
TGTCTCGGTCCATGACTCTGGAGATCCGAGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGGGATTGTTTTAGTGTTG
GCAGTAATGTTGATATAGATTTTTCTGGACCAACCATCTATGGCTGGGCTGTGTTGGCCTTCGAAGGGTGGCTTGCTGGCTATCAGATGA
GTTTTGACACAGCCAAATCCAAACTGTCACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCCAGCTGCACACACATGTGAACG
ATGGCACTGAATTTGGAGGTTCTATCTACCAGAAGGTGAATGAGAAGATTGAAACATCCATAAACCTTGCTTGGACAGCTGGGAGTAACA
ACACCCGTTTTGGCATTGCTGCTAAGTACATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATAATGCCAGCCTGATTGGACTGG
GTTATACTCAGACCCTTCGACCAGGAGTCAAATTGACTTTATCAGCTTTAATCGATGGGAAGAACTTCAGTGCAGGAGGTCACAAGGTTG

>79911_79911_7_SDHA-VDAC3_SDHA_chr5_233760_ENST00000504309_VDAC3_chr8_42259306_ENST00000521158_length(amino acids)=544AA_BP=368
MRRDWRDCAAATADMSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRA
AFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDG
KIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVAT
GGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRS
MTLEIREGRKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTE
FGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGF

--------------------------------------------------------------
>79911_79911_8_SDHA-VDAC3_SDHA_chr5_233760_ENST00000504309_VDAC3_chr8_42259306_ENST00000522572_length(transcript)=1483nt_BP=1117nt
GCAGGCGCAGTCTGCGCAGGGACTGGCGGGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCG
CTCGGCGCCTGGCGCTGGCCAAGGCGTGGCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGG
CATCTGCTAAAGTTTCAGATTCCATTTCTGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAG
GCTTGCGAGCTGCATTTGGCCTTTCTGAGGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAG
CACAGGGAGGAATCAATGCTGCTCTGGGGAACATGGAGGAGGACAACTGGAGGTGGCATTTCTACGACACCGTGAAGGGCTCCGACTGGC
TGGGGGACCAGGATGCCATCCACTACATGACGGAGCAGGCCCCCGCCGCCGTGGTCGAGCTAGAAAATTATGGCATGCCGTTTAGCAGAA
CTGAAGATGGGAAGATTTATCAGCGTGCATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGGCCCATCGGTGCTGCTGTGTGG
CTGATCGGACTGGCCACTCGCTATTGCACACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATTTTGTGGAGTATTTTGCCTTGG
ATCTCCTGATGGAGAATGGGGAGTGCCGTGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATCGCATAAGAGCAAAGAACACTG
TTGTTGCCACAGGAGGCTACGGGCGCACCTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACGGCACGGCCATGATCACCAGGG
CAGGCCTTCCTTGCCAGGACCTAGAGTTTGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTCTCATTACGGAAGGATGTCGTG
GAGAGGGAGGCATTCTCATTAACAGTCAAGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGGACCTGGCGTCTAGAGATGTGG
TGTCTCGGTCCATGACTCTGGAGATCCGAGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGGGATTGTTTTAGTGTTG
GCTTGGGATTTGAACTGGAAGCTTAATGTGGTTTGAGGAAAGCATCAGATTTGTCCCTGGAAGTGAAGAGAAATGAACCCACTATGTTTT
GGCCTTAAAATTCTTCTGTGAAATTTCAAAAGTGTGAACTTTTTATTCTTCCAAAGAATTGTAATCCTCCCCACACTGAAGTCTAGGGGT
TGCGAATCCCTCCTGAGGGAGATGCTTGAAGGCATGCCTGGAAGTTGTCATGTTTGTGCCACGTTTCAGTTCAGTTCTGAAGTGTTATTA

>79911_79911_8_SDHA-VDAC3_SDHA_chr5_233760_ENST00000504309_VDAC3_chr8_42259306_ENST00000522572_length(amino acids)=394AA_BP=368
MRRDWRDCAAATADMSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRA
AFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDG
KIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVAT
GGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRS

--------------------------------------------------------------
>79911_79911_9_SDHA-VDAC3_SDHA_chr5_233760_ENST00000510361_VDAC3_chr8_42259306_ENST00000022615_length(transcript)=1922nt_BP=958nt
GCAGGGACTGGCGGGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCGCTCGGCGCCTGGCGC
TGGCCAAGGCGTGGCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGGCATCTGCTAAAGTTT
CAGATTCCATTTCTGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAGGCTTGCGAGCTGCAT
TTGGCCTTTCTGAGGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAGCACAGCTAGAAAATT
ATGGCATGCCGTTTAGCAGAACTGAAGATGGGAAGATTTATCAGCGTGCATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGG
CCCATCGGTGCTGCTGTGTGGCTGATCGGACTGGCCACTCGCTATTGCACACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATT
TTGTGGAGTATTTTGCCTTGGATCTCCTGATGGAGAATGGGGAGTGCCGTGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATC
GCATAAGAGCAAAGAACACTGTTGTTGCCACAGGAGGCTACGGGCGCACCTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACG
GCACGGCCATGATCACCAGGGCAGGCCTTCCTTGCCAGGACCTAGAGTTTGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTC
TCATTACGGAAGGATGTCGTGGAGAGGGAGGCATTCTCATTAACAGTCAAGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGG
ACCTGGCGTCTAGAGATGTGGTGTCTCGGTCCATGACTCTGGAGATCCGAGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATA
AACGGGATTGTTTTAGTGTTGGCAGTAATGTTGATATAGATTTTTCTGGACCAACCATCTATGGCTGGGCTGTGTTGGCCTTCGAAGGGT
GGCTTGCTGGCTATCAGATGAGTTTTGACACAGCCAAATCCAAACTGTCACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCC
AGCTGCACACACATGTGAACGATGGCACTGAATTTGGAGGTTCTATCTACCAGAAGGTGAATGAGAAGATTGAAACATCCATAAACCTTG
CTTGGACAGCTGGGAGTAACAACACCCGTTTTGGCATTGCTGCTAAGTACATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATA
ATGCCAGCCTGATTGGACTGGGTTATACTCAGACCCTTCGACCAGGAGTCAAATTGACTTTATCAGCTTTAATCGATGGGAAGAACTTCA
GTGCAGGAGGTCACAAGGTTGGCTTGGGATTTGAACTGGAAGCTTAATGTGGTTTGAGGAAAGCATCAGATTTGTCCCTGGAAGTGAAGA
GAAATGAACCCACTATGTTTTGGCCTTAAAATTCTTCTGTGAAATTTCAAAAGTGTGAACTTTTTATTCTTCCAAAGAATTGTAATCCTC
CCCACACTGAAGTCTAGGGGTTGCGAATCCCTCCTGAGGGAGATGCTTGAAGGCATGCCTGGAAGTTGTCATGTTTGTGCCACGTTTCAG
TTCAGTTCTGAAGTGTTATTAAATGTGTTCCTCAGCGACAGTGTAGCGTCATGTTAGAGGAGACGATCTGACCCACCAGTTTGTACATCA
CGTCCTGCATGTCCCACACCATTTTTTCATGACCTTGTAATATACTGGTCTCTGTGCTATAGTGGAATCTTTGGTTTTGCATCATAGTAA

>79911_79911_9_SDHA-VDAC3_SDHA_chr5_233760_ENST00000510361_VDAC3_chr8_42259306_ENST00000022615_length(amino acids)=482AA_BP=306
MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACV
TKLFPTRSHTVAAQLENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEN
GECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGIL
INSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAK
SKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTL

--------------------------------------------------------------
>79911_79911_10_SDHA-VDAC3_SDHA_chr5_233760_ENST00000510361_VDAC3_chr8_42259306_ENST00000392935_length(transcript)=1918nt_BP=958nt
GCAGGGACTGGCGGGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCGCTCGGCGCCTGGCGC
TGGCCAAGGCGTGGCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGGCATCTGCTAAAGTTT
CAGATTCCATTTCTGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAGGCTTGCGAGCTGCAT
TTGGCCTTTCTGAGGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAGCACAGCTAGAAAATT
ATGGCATGCCGTTTAGCAGAACTGAAGATGGGAAGATTTATCAGCGTGCATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGG
CCCATCGGTGCTGCTGTGTGGCTGATCGGACTGGCCACTCGCTATTGCACACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATT
TTGTGGAGTATTTTGCCTTGGATCTCCTGATGGAGAATGGGGAGTGCCGTGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATC
GCATAAGAGCAAAGAACACTGTTGTTGCCACAGGAGGCTACGGGCGCACCTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACG
GCACGGCCATGATCACCAGGGCAGGCCTTCCTTGCCAGGACCTAGAGTTTGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTC
TCATTACGGAAGGATGTCGTGGAGAGGGAGGCATTCTCATTAACAGTCAAGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGG
ACCTGGCGTCTAGAGATGTGGTGTCTCGGTCCATGACTCTGGAGATCCGAGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATA
AACGGGATTGTTTTAGTGTTGGCAGTAATGTTGATATAGATTTTTCTGGACCAACCATCTATGGCTGGGCTGTGTTGGCCTTCGAAGGGT
GGCTTGCTGGCTATCAGATGAGTTTTGACACAGCCAAATCCAAACTGTCACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCC
AGCTGCACACACATGTGAACGATGGCACTGAATTTGGAGGTTCTATCTACCAGAAGGTGAATGAGAAGATTGAAACATCCATAAACCTTG
CTTGGACAGCTGGGAGTAACAACACCCGTTTTGGCATTGCTGCTAAGTACATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATA
ATGCCAGCCTGATTGGACTGGGTTATACTCAGACCCTTCGACCAGGAGTCAAATTGACTTTATCAGCTTTAATCGATGGGAAGAACTTCA
GTGCAGGAGGTCACAAGGTTGGCTTGGGATTTGAACTGGAAGCTTAATGTGGTTTGAGGAAAGCATCAGATTTGTCCCTGGAAGTGAAGA
GAAATGAACCCACTATGTTTTGGCCTTAAAATTCTTCTGTGAAATTTCAAAAGTGTGAACTTTTTATTCTTCCAAAGAATTGTAATCCTC
CCCACACTGAAGTCTAGGGGTTGCGAATCCCTCCTGAGGGAGATGCTTGAAGGCATGCCTGGAAGTTGTCATGTTTGTGCCACGTTTCAG
TTCAGTTCTGAAGTGTTATTAAATGTGTTCCTCAGCGACAGTGTAGCGTCATGTTAGAGGAGACGATCTGACCCACCAGTTTGTACATCA
CGTCCTGCATGTCCCACACCATTTTTTCATGACCTTGTAATATACTGGTCTCTGTGCTATAGTGGAATCTTTGGTTTTGCATCATAGTAA

>79911_79911_10_SDHA-VDAC3_SDHA_chr5_233760_ENST00000510361_VDAC3_chr8_42259306_ENST00000392935_length(amino acids)=482AA_BP=306
MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACV
TKLFPTRSHTVAAQLENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEN
GECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGIL
INSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAK
SKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTL

--------------------------------------------------------------
>79911_79911_11_SDHA-VDAC3_SDHA_chr5_233760_ENST00000510361_VDAC3_chr8_42259306_ENST00000521158_length(transcript)=1513nt_BP=958nt
GCAGGGACTGGCGGGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCGCTCGGCGCCTGGCGC
TGGCCAAGGCGTGGCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGGCATCTGCTAAAGTTT
CAGATTCCATTTCTGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAGGCTTGCGAGCTGCAT
TTGGCCTTTCTGAGGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAGCACAGCTAGAAAATT
ATGGCATGCCGTTTAGCAGAACTGAAGATGGGAAGATTTATCAGCGTGCATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGG
CCCATCGGTGCTGCTGTGTGGCTGATCGGACTGGCCACTCGCTATTGCACACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATT
TTGTGGAGTATTTTGCCTTGGATCTCCTGATGGAGAATGGGGAGTGCCGTGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATC
GCATAAGAGCAAAGAACACTGTTGTTGCCACAGGAGGCTACGGGCGCACCTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACG
GCACGGCCATGATCACCAGGGCAGGCCTTCCTTGCCAGGACCTAGAGTTTGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTC
TCATTACGGAAGGATGTCGTGGAGAGGGAGGCATTCTCATTAACAGTCAAGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGG
ACCTGGCGTCTAGAGATGTGGTGTCTCGGTCCATGACTCTGGAGATCCGAGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATA
AACGGGATTGTTTTAGTGTTGGCAGTAATGTTGATATAGATTTTTCTGGACCAACCATCTATGGCTGGGCTGTGTTGGCCTTCGAAGGGT
GGCTTGCTGGCTATCAGATGAGTTTTGACACAGCCAAATCCAAACTGTCACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCC
AGCTGCACACACATGTGAACGATGGCACTGAATTTGGAGGTTCTATCTACCAGAAGGTGAATGAGAAGATTGAAACATCCATAAACCTTG
CTTGGACAGCTGGGAGTAACAACACCCGTTTTGGCATTGCTGCTAAGTACATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATA
ATGCCAGCCTGATTGGACTGGGTTATACTCAGACCCTTCGACCAGGAGTCAAATTGACTTTATCAGCTTTAATCGATGGGAAGAACTTCA

>79911_79911_11_SDHA-VDAC3_SDHA_chr5_233760_ENST00000510361_VDAC3_chr8_42259306_ENST00000521158_length(amino acids)=482AA_BP=306
MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACV
TKLFPTRSHTVAAQLENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEN
GECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGIL
INSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAK
SKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTL

--------------------------------------------------------------
>79911_79911_12_SDHA-VDAC3_SDHA_chr5_233760_ENST00000510361_VDAC3_chr8_42259306_ENST00000522572_length(transcript)=1324nt_BP=958nt
GCAGGGACTGGCGGGACTGCGCGGCGGCAACAGCAGACATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCGCTCGGCGCCTGGCGC
TGGCCAAGGCGTGGCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGGCATCTGCTAAAGTTT
CAGATTCCATTTCTGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAGGCTTGCGAGCTGCAT
TTGGCCTTTCTGAGGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAGCACAGCTAGAAAATT
ATGGCATGCCGTTTAGCAGAACTGAAGATGGGAAGATTTATCAGCGTGCATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGG
CCCATCGGTGCTGCTGTGTGGCTGATCGGACTGGCCACTCGCTATTGCACACCTTATATGGAAGGTCTCTGCGATATGATACCAGCTATT
TTGTGGAGTATTTTGCCTTGGATCTCCTGATGGAGAATGGGGAGTGCCGTGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATC
GCATAAGAGCAAAGAACACTGTTGTTGCCACAGGAGGCTACGGGCGCACCTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACG
GCACGGCCATGATCACCAGGGCAGGCCTTCCTTGCCAGGACCTAGAGTTTGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTC
TCATTACGGAAGGATGTCGTGGAGAGGGAGGCATTCTCATTAACAGTCAAGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGG
ACCTGGCGTCTAGAGATGTGGTGTCTCGGTCCATGACTCTGGAGATCCGAGAAGGAAGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATA
AACGGGATTGTTTTAGTGTTGGCTTGGGATTTGAACTGGAAGCTTAATGTGGTTTGAGGAAAGCATCAGATTTGTCCCTGGAAGTGAAGA
GAAATGAACCCACTATGTTTTGGCCTTAAAATTCTTCTGTGAAATTTCAAAAGTGTGAACTTTTTATTCTTCCAAAGAATTGTAATCCTC
CCCACACTGAAGTCTAGGGGTTGCGAATCCCTCCTGAGGGAGATGCTTGAAGGCATGCCTGGAAGTTGTCATGTTTGTGCCACGTTTCAG

>79911_79911_12_SDHA-VDAC3_SDHA_chr5_233760_ENST00000510361_VDAC3_chr8_42259306_ENST00000522572_length(amino acids)=332AA_BP=306
MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACV
TKLFPTRSHTVAAQLENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEN
GECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGIL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SDHA-VDAC3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for SDHA-VDAC3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for SDHA-VDAC3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source