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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SEC16A-LHX3 (FusionGDB2 ID:80010)

Fusion Gene Summary for SEC16A-LHX3

check button Fusion gene summary
Fusion gene informationFusion gene name: SEC16A-LHX3
Fusion gene ID: 80010
HgeneTgene
Gene symbol

SEC16A

LHX3

Gene ID

9919

8022

Gene nameSEC16 homolog A, endoplasmic reticulum export factorLIM homeobox 3
SynonymsKIAA0310|SEC16L|p250CPHD3|LIM3|M2-LHX3
Cytomap

9q34.3

9q34.3

Type of geneprotein-codingprotein-coding
Descriptionprotein transport protein Sec16Aprotein SEC16 homolog ALIM/homeobox protein Lhx3LIM homeobox protein 3LIM/homeodomain protein LHX3
Modification date2020031320200329
UniProtAcc.

Q9UBR4

Ensembl transtripts involved in fusion geneENST00000290037, ENST00000313050, 
ENST00000371706, ENST00000431893, 
ENST00000313084, ENST00000398335, 
ENST00000467838, 		ENST00000371746, 
ENST00000371748, 
Fusion gene scores* DoF score12 X 11 X 10=13202 X 1 X 2=4
# samples 152
** MAII scorelog2(15/1320*10)=-3.13750352374993
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/4*10)=2.32192809488736
Context

PubMed: SEC16A [Title/Abstract] AND LHX3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSEC16A(139362867)-LHX3(139092599), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSEC16A

GO:0007029

endoplasmic reticulum organization

21768384

HgeneSEC16A

GO:0034976

response to endoplasmic reticulum stress

28067262

TgeneLHX3

GO:0045944

positive regulation of transcription by RNA polymerase II

15271874


check buttonFusion gene breakpoints across SEC16A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LHX3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A0CX-01ASEC16Achr9

139362867

-LHX3chr9

139092599

-


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Fusion Gene ORF analysis for SEC16A-LHX3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000290037ENST00000371746SEC16Achr9

139362867

-LHX3chr9

139092599

-
In-frameENST00000290037ENST00000371748SEC16Achr9

139362867

-LHX3chr9

139092599

-
In-frameENST00000313050ENST00000371746SEC16Achr9

139362867

-LHX3chr9

139092599

-
In-frameENST00000313050ENST00000371748SEC16Achr9

139362867

-LHX3chr9

139092599

-
In-frameENST00000371706ENST00000371746SEC16Achr9

139362867

-LHX3chr9

139092599

-
In-frameENST00000371706ENST00000371748SEC16Achr9

139362867

-LHX3chr9

139092599

-
In-frameENST00000431893ENST00000371746SEC16Achr9

139362867

-LHX3chr9

139092599

-
In-frameENST00000431893ENST00000371748SEC16Achr9

139362867

-LHX3chr9

139092599

-
intron-3CDSENST00000313084ENST00000371746SEC16Achr9

139362867

-LHX3chr9

139092599

-
intron-3CDSENST00000313084ENST00000371748SEC16Achr9

139362867

-LHX3chr9

139092599

-
intron-3CDSENST00000398335ENST00000371746SEC16Achr9

139362867

-LHX3chr9

139092599

-
intron-3CDSENST00000398335ENST00000371748SEC16Achr9

139362867

-LHX3chr9

139092599

-
intron-3CDSENST00000467838ENST00000371746SEC16Achr9

139362867

-LHX3chr9

139092599

-
intron-3CDSENST00000467838ENST00000371748SEC16Achr9

139362867

-LHX3chr9

139092599

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000313050SEC16Achr9139362867-ENST00000371746LHX3chr9139092599-606638762949901653
ENST00000313050SEC16Achr9139362867-ENST00000371748LHX3chr9139092599-606538762949901653
ENST00000371706SEC16Achr9139362867-ENST00000371746LHX3chr9139092599-549233023444161460
ENST00000371706SEC16Achr9139362867-ENST00000371748LHX3chr9139092599-549133023444161460
ENST00000290037SEC16Achr9139362867-ENST00000371746LHX3chr9139092599-54583268043821460
ENST00000290037SEC16Achr9139362867-ENST00000371748LHX3chr9139092599-54573268043821460
ENST00000431893SEC16Achr9139362867-ENST00000371746LHX3chr9139092599-54583268043821460
ENST00000431893SEC16Achr9139362867-ENST00000371748LHX3chr9139092599-54573268043821460

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000313050ENST00000371746SEC16Achr9139362867-LHX3chr9139092599-0.0022131510.9977869
ENST00000313050ENST00000371748SEC16Achr9139362867-LHX3chr9139092599-0.0022117560.9977882
ENST00000371706ENST00000371746SEC16Achr9139362867-LHX3chr9139092599-0.0016988250.9983012
ENST00000371706ENST00000371748SEC16Achr9139362867-LHX3chr9139092599-0.0016976290.99830234
ENST00000290037ENST00000371746SEC16Achr9139362867-LHX3chr9139092599-0.0015913260.99840873
ENST00000290037ENST00000371748SEC16Achr9139362867-LHX3chr9139092599-0.0015909180.9984091
ENST00000431893ENST00000371746SEC16Achr9139362867-LHX3chr9139092599-0.0015913260.99840873
ENST00000431893ENST00000371748SEC16Achr9139362867-LHX3chr9139092599-0.0015909180.9984091

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Fusion Genomic Features for SEC16A-LHX3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SEC16A-LHX3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:139362867/chr9:139092599)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.LHX3

Q9UBR4

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1. {ECO:0000250, ECO:0000269|PubMed:21149718}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLHX3chr9:139362867chr9:139092599ENST0000037174606157_21631403.0DNA bindingHomeobox
TgeneLHX3chr9:139362867chr9:139092599ENST0000037174806157_21626398.0DNA bindingHomeobox
TgeneLHX3chr9:139362867chr9:139092599ENST000003717460631_8131403.0DomainLIM zinc-binding 1
TgeneLHX3chr9:139362867chr9:139092599ENST000003717460690_14431403.0DomainLIM zinc-binding 2
TgeneLHX3chr9:139362867chr9:139092599ENST000003717480631_8126398.0DomainLIM zinc-binding 1
TgeneLHX3chr9:139362867chr9:139092599ENST000003717480690_14426398.0DomainLIM zinc-binding 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSEC16Achr9:139362867chr9:139092599ENST00000290037-3291113_118110892160.0Compositional biasNote=Pro-rich
HgeneSEC16Achr9:139362867chr9:139092599ENST00000290037-3291159_116210892160.0Compositional biasNote=Poly-Tyr
HgeneSEC16Achr9:139362867chr9:139092599ENST00000290037-3291591_159410892160.0Compositional biasNote=Poly-Glu
HgeneSEC16Achr9:139362867chr9:139092599ENST00000290037-3291931_228510892160.0Compositional biasNote=Pro-rich
HgeneSEC16Achr9:139362867chr9:139092599ENST00000371706-3281113_118110892135.0Compositional biasNote=Pro-rich
HgeneSEC16Achr9:139362867chr9:139092599ENST00000371706-3281159_116210892135.0Compositional biasNote=Poly-Tyr
HgeneSEC16Achr9:139362867chr9:139092599ENST00000371706-3281591_159410892135.0Compositional biasNote=Poly-Glu
HgeneSEC16Achr9:139362867chr9:139092599ENST00000371706-3281931_228510892135.0Compositional biasNote=Pro-rich
HgeneSEC16Achr9:139362867chr9:139092599ENST00000431893-3291113_118110892155.0Compositional biasNote=Pro-rich
HgeneSEC16Achr9:139362867chr9:139092599ENST00000431893-3291159_116210892155.0Compositional biasNote=Poly-Tyr
HgeneSEC16Achr9:139362867chr9:139092599ENST00000431893-3291591_159410892155.0Compositional biasNote=Poly-Glu
HgeneSEC16Achr9:139362867chr9:139092599ENST00000431893-3291931_228510892155.0Compositional biasNote=Pro-rich
HgeneSEC16Achr9:139362867chr9:139092599ENST00000290037-3291019_189010892160.0RegionRequired for localization to endoplasmic reticulum exit sites
HgeneSEC16Achr9:139362867chr9:139092599ENST00000290037-3291102_140510892160.0RegionRequired for endoplasmic reticulum localization
HgeneSEC16Achr9:139362867chr9:139092599ENST00000371706-3281019_189010892135.0RegionRequired for localization to endoplasmic reticulum exit sites
HgeneSEC16Achr9:139362867chr9:139092599ENST00000371706-3281102_140510892135.0RegionRequired for endoplasmic reticulum localization
HgeneSEC16Achr9:139362867chr9:139092599ENST00000431893-3291019_189010892155.0RegionRequired for localization to endoplasmic reticulum exit sites
HgeneSEC16Achr9:139362867chr9:139092599ENST00000431893-3291102_140510892155.0RegionRequired for endoplasmic reticulum localization


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Fusion Gene Sequence for SEC16A-LHX3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80010_80010_1_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000290037_LHX3_chr9_139092599_ENST00000371746_length(transcript)=5458nt_BP=3268nt
ATGCCTGGGCTCGACCGACCCCTGAGCAGGCAAAACCCACATGACGGTGTGGTCACCCCAGCAGCATCCCCTTCCCTCCCTCAGCCTGGT
CTGCAGATGCCAGGACAGTGGGGGCCAGTGCAGGGAGGCCCACAGCCCTCGGGGCAACATCGTTCACCCTGCCCTGAAGGACCTGTTCCC
AGCGGGGTGCCCTGTGCCACCAGCGTTCCTCATTTCCCCACCCCGTCCATCCTACATCAGGGCCCTGGTCATGAGCAACACAGCCCTCTG
GTGGCTCCCCCAGCAGCCTTGCCCAGTGACGGAAGAGACGAGGTGAGCCACTTGCAAAGTGGAAGCCACCTGGCCAATAACTCTGATCCT
GAAAGTACATTCAGGCAAAATCCCAGAATTGTGAATCACTGGGCAAGCCCAGAGCTCAGGCAGAATCCAGGAGTGAAGAATGAGCACCGG
CCCGCCTCTGCTCTTGTGAACCCCCTCGCCCGGGGAGATAGCCCAGAAAACCGTACGCACCACCCACTGGGGGCTGGGGCCGGGTCTGGC
TGTGCCCCGCTAGAAGCAGACTCAGGAGCTTCAGGAGCTCTGGCGATGTTTTTCCAAGGGGGAGAGACAGAAAATGAGGAGAATCTCTCA
TCTGAAAAAGCAGGCTTATCTGGTCAAGCGGACTTTGACGATTTCTGCTCCAGCCCTGGGCTAGGCCGTCCGCCCGCACCTACACACGTG
GGGGCAGGCAGCCTCTGCCAGGCCCTTCTCCCAGGCCCCAGCAATGAGGCTGCTGGTGATGTGTGGGGTGACACAGCGAGCACAGGGGTG
CCGGATGCCAGCGGCTCGCAGTATGAGAATGTTGAGAACTTAGAATTTGTTCAGAATCAAGAAGTTCTGCCAAGTGAGCCCCTCAATTTG
GACCCTTCCTCCCCGAGTGACCAGTTCAGATATGGGCCCCTTCCTGGGCCAGCTGTGCCCAGGCATGGTGCTGTGTGCCACACCGGAGCC
CCTGATGCCACACTGCATACAGTGCACCCTGACAGCGTGTCATCCAGCTATAGCAGCAGAAGCCACGGAAGGCTCTCAGGCTCAGCCAGG
CCCCAGGAGCTGGTTGGCACATTCATTCAGCAAGAAGTTGGAAAACCCGAGGATGAAGCTTCAGGTAGTTTTTTTAAGCAAATCGATTCT
TCTCCCGTAGGAGGTGAAACAGACGAGACCACTGTGAGCCAGAATTACCGTGGCAGCGTGTCCCAGCCCTCAACCCCGAGCCCCCCGAAA
CCTACAGGAATATTTCAGACAAGTGCAAATAGTTCTTTCGAACCGGTAAAATCTCACTTAGTTGGGGTAAAACCATTTGAGGCAGATCGC
GCCAACGTGGTTGGTGAAGTAAGGGAGACCTGTGTCCGCCAGAAGCAGTGCAGACCAGCTGCCGCCCTGCCCGATGCTTCCCCTGGCAAC
CTGGAGCAGCCACCAGACAACATGGAGACCCTCTGTGCACCCCAGGTCTGTCCCCTGCCTCTTAACTCCACCACGGAAGCTGTGCACATG
CTTCCGCACGCAGGGGCACCGCCCTTGGATACTGTGTATCCAGCACCCGAGAAGAGGCCTTCAGCCAGGACCCAGGGGCCCGTGAAGTGT
GAGAGCCCAGCAACGACTCTGTGGGCGCAAAGTGAGCTGCCAGATTTTGGAGGCAACGTCCTTCTGGCCCCTGCAGCCCCGGCGCTTTAT
GTGTGTGCAAAACCTCAGCCACCTGTTGTTCAGCCTCCAGAAGAGGCGATGTCCGGGCAGCAGTCACGGAACCCAAGCTCGGCGGCCCCG
GTGCAGAGCCGAGGTGGCATTGGTGCTTCTGAGAACCTTGAGAATCCTCCCAAAATGGGAGAGGAGGAGGCCCTTCAGTCCCAGGCGAGT
TCTGGTTATGCAAGTTTATTATCCTCACCGCCCACTGAGTCTCTGCAGAATCCTCCAGTCTTGATTGCTCAGCCTGATCACAGCTATAAT
CTGGCTCAGCCCATTAACTTTTCTGTGTCCTTATCGAACTCTCATGAGAAGAATCAGTCCTGGAGAGAGGCTTTGGTGGGGGATAGACCT
GCAGTCAGCAGTTGGGCTCTCGGTGGTGATTCTGGGGAGAACACTTCTTTGTCTGGGATTCCAACCAGCTCTGTCCTTAGCTTGTCTCTG
CCTAGCAGTGTTGCCCAAAGTAATTTTCCACAAGGTTCTGGTGCTTCCGAAATGGTTTCTAATCAGCCTGCTAATTTGCTGGTTCAACCA
CCATCCCAGCCAGTTCCAGAGAACTTGGTTCCAGAAAGTCAAAAGGATCGTAAGGCAGGAAGTGCTCTTCCCGGATTTGCTAATAGCCCT
GCTGGAAGCACAAGTGTGGTGTTAGTTCCACCTGCACACGGCACCCTGGTGCCTGATGGTAATAAGGCAAACCATTCCAGTCATCAGGAA
GACACTTACGGAGCCCTAGACTTTACCTTAAGCAGGACTTTGGAAAATCCTGTAAACGTGTACAACCCGTCCCATTCTGACAGCCTCGCT
TCTCAGCAAAGTGTTGCCAGTCATCCCAGACAATCTGGGCCTGGGGCGCCTAACCTTGACCGTTTTTATCAGCAGGTCACGAAAGATGCC
CAGGGCCAGCCTGGCCTCGAAAGAGCCCAGCAGGAGCTGGTGCCACCCCAGCAACAGGCTTCTCCCCCACAACTACCCAAAGCCATGTTT
TCGGAGCTGTCAAATCCAGAAAGTCTGCCCGCACAGGGACAGGCCCAGAACTCAGCACAGTCACCAGCAAGTCTGGTTCTGGTCGACGCG
GGTCAGCAGCTGCCCCCTCGGCCTCCTCAGTCCTCTAGCGTGTCTCTGGTGTCCAGTGGCTCCGGCCAGGCAGCTGTGCCGTCAGAGCAG
CCGTGGCCACAGCCAGTGCCTGCACTTGCCCCCGGCCCACCGCCTCAGGACCTGGCCGCCTACTACTACTACCGGCCTTTGTACGATGCC
TACCAGCCTCAGTACTCTTTGCCGTACCCACCGGAGCCTGGCGCAGCCTCCCTCTATTACCAGGATGTCTACAGCCTCTATGAGCCTCGA
TACAGGCCCTATGATGGTGCTGCGTCTGCTTACGCCCAGAACTACCGCTATCCCGAGCCCGAGCGGCCCAGCTCCCGAGCCAGCCACTCC
TCGGAACGGCCACCTCCCAGGCAAGGATATCCTGAAGGATACTATAGTTCCAAAAGTGGATGGAGCAGTCAGAGCGATTACTATGCAAGC
TATTACTCCAGCCAGTACGATTATGGAGAGATCCCGCTGTGCGCTGGCTGTGACCAGCACATCCTGGACCGCTTCATCCTCAAGGCTCTG
GACCGCCACTGGCACAGCAAGTGTCTCAAGTGCAGCGACTGCCACACGCCACTGGCCGAGCGCTGCTTCAGCCGAGGGGAGAGCGTTTAC
TGCAAGGACGACTTTTTCAAGCGCTTCGGGACCAAGTGCGCCGCGTGCCAGCTGGGCATCCCGCCCACGCAGGTGGTGCGCCGCGCCCAG
GACTTCGTGTACCACCTGCACTGCTTTGCCTGCGTCGTGTGCAAGCGGCAGCTGGCCACGGGCGACGAGTTCTACCTCATGGAGGACAGC
CGGCTCGTGTGCAAGGCGGACTACGAAACCGCCAAGCAGCGAGAGGCCGAGGCCACGGCCAAGCGGCCGCGCACGACCATCACCGCCAAG
CAGCTGGAGACGCTGAAGAGCGCTTACAACACCTCGCCCAAGCCGGCGCGCCACGTGCGCGAGCAGCTCTCGTCCGAGACGGGCCTGGAC
ATGCGCGTGGTGCAGGTTTGGTTCCAGAACCGCCGGGCCAAGGAGAAGAGGCTGAAGAAGGACGCCGGCCGGCAGCGCTGGGGGCAGTAT
TTCCGCAACATGAAGCGCTCCCGCGGCGGCTCCAAGTCGGACAAGGACAGCGTTCAGGAGGGGCAGGACAGCGACGCTGAGGTCTCCTTC
CCCGATGAGCCTTCCTTGGCGGAAATGGGCCCGGCCAATGGCCTCTACGGGAGCTTGGGGGAACCCACCCAGGCCTTGGGCCGGCCCTCG
GGAGCCCTGGGCAACTTCTCCCTGGAGCATGGAGGCCTGGCAGGCCCAGAGCAGTACCGAGAGCTGCGTCCCGGCAGCCCCTACGGTGTC
CCCCCATCCCCCGCCGCCCCGCAGAGCCTCCCTGGCCCCCAGCCCCTCCTCTCCAGCCTGGTGTACCCAGACACCAGCTTGGGCCTTGTG
CCCTCGGGAGCCCCCGGCGGGCCCCCACCCATGAGGGTGCTGGCAGGGAACGGACCCAGTTCTGACCTATCCACGGGGAGCAGCGGGGGT
TACCCCGACTTCCCTGCCAGCCCCGCCTCCTGGCTGGATGAGGTAGACCACGCTCAGTTCTGACCCAGGCCCGGCTCCACCCTGCACCTC
ACACGAGGGAGCTGCCCCTGGGTGGGCGGCTCGGGGCTGCTGGGGTTTCCGAGGAAGTGGGGCCAGGGCGTCAAGGGAGGGCTGGTGCCT
TCGGAGCCTCCCACTGCCGACCGCACAGCTCCCTCTCTGGGGGCTGAGGGACCCACCTGGCCCCTCCTCTGACACAGGGCTGGCCCGCCA
GGTGGCCTCCCAGCAAGCCAGCCTTTTTTGTAAGCAAATTTCTCCCCTTTATTGACCAATTAACTGAGCACTTGCTGCTATTTCTAGACA
TGAAATGTCACCTTGCTGAGGCCCAGCCCAGCCCAGCATAGCCCGAGGGCTGGAAAAACGCTTTCATCTCTAAAACTGAGAAATCATCAT
AATTGTGCTTTCACTTCCCAGGCTCCATGTGTCTTGGAGCCGTCACCCCGAGGCTCCCTCTTTAGGTCGGAGATTGGCCTTGCCTGTCGA
GGCAAGAGGCTGCAGAGGCGGGGACACACCTGTGTCCTCCGGGAGAGGCCCCCTCCTCTCCCCAGACCACAGGGGGCCTCTCTGCCTCCA
GCCCCACCTTCCCCGGGAGAAGCTTTCCCCAATCCCCAGGTCTCTAGATCATTCTGTTCTCGAGTATCCTGTGGAGGAGGCAAAAATGCC
TGGCGCCCCTTCTCTCCAAGCTCAATTCTCTAAGCCCCTCAGGGTCTCCTCCTCACCCCACCCCAGGCCCTTGGTGTCCAGGCTGCACCC
ACAGATGTCTGTTGCCAAACAGCCTGCCCTCCCTGCCGGAGCCGGCTCTGCCAGCCCCAGATTGGGAAGTCTCCCCGCTGGAGAAGGGTG
GGGCTCCTCTGAGCCTGCCCTGCCTCCTCCATCAGATCCTTTGGGAAGAAGTTTCTGGGAGATGCCCGCAGCTGTGCGTGCCCCAGACAC
AAAGGCTGGCCTGTGTGTAAGTCAAAGTCACTCCCGCAAACCTGAATCTCGAGCTACCTATTGGTTCTGTGAATGTTCTGTGTCTTTTAT

>80010_80010_1_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000290037_LHX3_chr9_139092599_ENST00000371746_length(amino acids)=1460AA_BP=0
MPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPL
VAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSG
CAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGV
PDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSAR
PQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADR
ANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKC
ESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQAS
SGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSL
PSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQE
DTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMF
SELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDA
YQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYAS
YYSSQYDYGEIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQ
DFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLD
MRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPS
GALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGG

--------------------------------------------------------------
>80010_80010_2_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000290037_LHX3_chr9_139092599_ENST00000371748_length(transcript)=5457nt_BP=3268nt
ATGCCTGGGCTCGACCGACCCCTGAGCAGGCAAAACCCACATGACGGTGTGGTCACCCCAGCAGCATCCCCTTCCCTCCCTCAGCCTGGT
CTGCAGATGCCAGGACAGTGGGGGCCAGTGCAGGGAGGCCCACAGCCCTCGGGGCAACATCGTTCACCCTGCCCTGAAGGACCTGTTCCC
AGCGGGGTGCCCTGTGCCACCAGCGTTCCTCATTTCCCCACCCCGTCCATCCTACATCAGGGCCCTGGTCATGAGCAACACAGCCCTCTG
GTGGCTCCCCCAGCAGCCTTGCCCAGTGACGGAAGAGACGAGGTGAGCCACTTGCAAAGTGGAAGCCACCTGGCCAATAACTCTGATCCT
GAAAGTACATTCAGGCAAAATCCCAGAATTGTGAATCACTGGGCAAGCCCAGAGCTCAGGCAGAATCCAGGAGTGAAGAATGAGCACCGG
CCCGCCTCTGCTCTTGTGAACCCCCTCGCCCGGGGAGATAGCCCAGAAAACCGTACGCACCACCCACTGGGGGCTGGGGCCGGGTCTGGC
TGTGCCCCGCTAGAAGCAGACTCAGGAGCTTCAGGAGCTCTGGCGATGTTTTTCCAAGGGGGAGAGACAGAAAATGAGGAGAATCTCTCA
TCTGAAAAAGCAGGCTTATCTGGTCAAGCGGACTTTGACGATTTCTGCTCCAGCCCTGGGCTAGGCCGTCCGCCCGCACCTACACACGTG
GGGGCAGGCAGCCTCTGCCAGGCCCTTCTCCCAGGCCCCAGCAATGAGGCTGCTGGTGATGTGTGGGGTGACACAGCGAGCACAGGGGTG
CCGGATGCCAGCGGCTCGCAGTATGAGAATGTTGAGAACTTAGAATTTGTTCAGAATCAAGAAGTTCTGCCAAGTGAGCCCCTCAATTTG
GACCCTTCCTCCCCGAGTGACCAGTTCAGATATGGGCCCCTTCCTGGGCCAGCTGTGCCCAGGCATGGTGCTGTGTGCCACACCGGAGCC
CCTGATGCCACACTGCATACAGTGCACCCTGACAGCGTGTCATCCAGCTATAGCAGCAGAAGCCACGGAAGGCTCTCAGGCTCAGCCAGG
CCCCAGGAGCTGGTTGGCACATTCATTCAGCAAGAAGTTGGAAAACCCGAGGATGAAGCTTCAGGTAGTTTTTTTAAGCAAATCGATTCT
TCTCCCGTAGGAGGTGAAACAGACGAGACCACTGTGAGCCAGAATTACCGTGGCAGCGTGTCCCAGCCCTCAACCCCGAGCCCCCCGAAA
CCTACAGGAATATTTCAGACAAGTGCAAATAGTTCTTTCGAACCGGTAAAATCTCACTTAGTTGGGGTAAAACCATTTGAGGCAGATCGC
GCCAACGTGGTTGGTGAAGTAAGGGAGACCTGTGTCCGCCAGAAGCAGTGCAGACCAGCTGCCGCCCTGCCCGATGCTTCCCCTGGCAAC
CTGGAGCAGCCACCAGACAACATGGAGACCCTCTGTGCACCCCAGGTCTGTCCCCTGCCTCTTAACTCCACCACGGAAGCTGTGCACATG
CTTCCGCACGCAGGGGCACCGCCCTTGGATACTGTGTATCCAGCACCCGAGAAGAGGCCTTCAGCCAGGACCCAGGGGCCCGTGAAGTGT
GAGAGCCCAGCAACGACTCTGTGGGCGCAAAGTGAGCTGCCAGATTTTGGAGGCAACGTCCTTCTGGCCCCTGCAGCCCCGGCGCTTTAT
GTGTGTGCAAAACCTCAGCCACCTGTTGTTCAGCCTCCAGAAGAGGCGATGTCCGGGCAGCAGTCACGGAACCCAAGCTCGGCGGCCCCG
GTGCAGAGCCGAGGTGGCATTGGTGCTTCTGAGAACCTTGAGAATCCTCCCAAAATGGGAGAGGAGGAGGCCCTTCAGTCCCAGGCGAGT
TCTGGTTATGCAAGTTTATTATCCTCACCGCCCACTGAGTCTCTGCAGAATCCTCCAGTCTTGATTGCTCAGCCTGATCACAGCTATAAT
CTGGCTCAGCCCATTAACTTTTCTGTGTCCTTATCGAACTCTCATGAGAAGAATCAGTCCTGGAGAGAGGCTTTGGTGGGGGATAGACCT
GCAGTCAGCAGTTGGGCTCTCGGTGGTGATTCTGGGGAGAACACTTCTTTGTCTGGGATTCCAACCAGCTCTGTCCTTAGCTTGTCTCTG
CCTAGCAGTGTTGCCCAAAGTAATTTTCCACAAGGTTCTGGTGCTTCCGAAATGGTTTCTAATCAGCCTGCTAATTTGCTGGTTCAACCA
CCATCCCAGCCAGTTCCAGAGAACTTGGTTCCAGAAAGTCAAAAGGATCGTAAGGCAGGAAGTGCTCTTCCCGGATTTGCTAATAGCCCT
GCTGGAAGCACAAGTGTGGTGTTAGTTCCACCTGCACACGGCACCCTGGTGCCTGATGGTAATAAGGCAAACCATTCCAGTCATCAGGAA
GACACTTACGGAGCCCTAGACTTTACCTTAAGCAGGACTTTGGAAAATCCTGTAAACGTGTACAACCCGTCCCATTCTGACAGCCTCGCT
TCTCAGCAAAGTGTTGCCAGTCATCCCAGACAATCTGGGCCTGGGGCGCCTAACCTTGACCGTTTTTATCAGCAGGTCACGAAAGATGCC
CAGGGCCAGCCTGGCCTCGAAAGAGCCCAGCAGGAGCTGGTGCCACCCCAGCAACAGGCTTCTCCCCCACAACTACCCAAAGCCATGTTT
TCGGAGCTGTCAAATCCAGAAAGTCTGCCCGCACAGGGACAGGCCCAGAACTCAGCACAGTCACCAGCAAGTCTGGTTCTGGTCGACGCG
GGTCAGCAGCTGCCCCCTCGGCCTCCTCAGTCCTCTAGCGTGTCTCTGGTGTCCAGTGGCTCCGGCCAGGCAGCTGTGCCGTCAGAGCAG
CCGTGGCCACAGCCAGTGCCTGCACTTGCCCCCGGCCCACCGCCTCAGGACCTGGCCGCCTACTACTACTACCGGCCTTTGTACGATGCC
TACCAGCCTCAGTACTCTTTGCCGTACCCACCGGAGCCTGGCGCAGCCTCCCTCTATTACCAGGATGTCTACAGCCTCTATGAGCCTCGA
TACAGGCCCTATGATGGTGCTGCGTCTGCTTACGCCCAGAACTACCGCTATCCCGAGCCCGAGCGGCCCAGCTCCCGAGCCAGCCACTCC
TCGGAACGGCCACCTCCCAGGCAAGGATATCCTGAAGGATACTATAGTTCCAAAAGTGGATGGAGCAGTCAGAGCGATTACTATGCAAGC
TATTACTCCAGCCAGTACGATTATGGAGAGATCCCGCTGTGCGCTGGCTGTGACCAGCACATCCTGGACCGCTTCATCCTCAAGGCTCTG
GACCGCCACTGGCACAGCAAGTGTCTCAAGTGCAGCGACTGCCACACGCCACTGGCCGAGCGCTGCTTCAGCCGAGGGGAGAGCGTTTAC
TGCAAGGACGACTTTTTCAAGCGCTTCGGGACCAAGTGCGCCGCGTGCCAGCTGGGCATCCCGCCCACGCAGGTGGTGCGCCGCGCCCAG
GACTTCGTGTACCACCTGCACTGCTTTGCCTGCGTCGTGTGCAAGCGGCAGCTGGCCACGGGCGACGAGTTCTACCTCATGGAGGACAGC
CGGCTCGTGTGCAAGGCGGACTACGAAACCGCCAAGCAGCGAGAGGCCGAGGCCACGGCCAAGCGGCCGCGCACGACCATCACCGCCAAG
CAGCTGGAGACGCTGAAGAGCGCTTACAACACCTCGCCCAAGCCGGCGCGCCACGTGCGCGAGCAGCTCTCGTCCGAGACGGGCCTGGAC
ATGCGCGTGGTGCAGGTTTGGTTCCAGAACCGCCGGGCCAAGGAGAAGAGGCTGAAGAAGGACGCCGGCCGGCAGCGCTGGGGGCAGTAT
TTCCGCAACATGAAGCGCTCCCGCGGCGGCTCCAAGTCGGACAAGGACAGCGTTCAGGAGGGGCAGGACAGCGACGCTGAGGTCTCCTTC
CCCGATGAGCCTTCCTTGGCGGAAATGGGCCCGGCCAATGGCCTCTACGGGAGCTTGGGGGAACCCACCCAGGCCTTGGGCCGGCCCTCG
GGAGCCCTGGGCAACTTCTCCCTGGAGCATGGAGGCCTGGCAGGCCCAGAGCAGTACCGAGAGCTGCGTCCCGGCAGCCCCTACGGTGTC
CCCCCATCCCCCGCCGCCCCGCAGAGCCTCCCTGGCCCCCAGCCCCTCCTCTCCAGCCTGGTGTACCCAGACACCAGCTTGGGCCTTGTG
CCCTCGGGAGCCCCCGGCGGGCCCCCACCCATGAGGGTGCTGGCAGGGAACGGACCCAGTTCTGACCTATCCACGGGGAGCAGCGGGGGT
TACCCCGACTTCCCTGCCAGCCCCGCCTCCTGGCTGGATGAGGTAGACCACGCTCAGTTCTGACCCAGGCCCGGCTCCACCCTGCACCTC
ACACGAGGGAGCTGCCCCTGGGTGGGCGGCTCGGGGCTGCTGGGGTTTCCGAGGAAGTGGGGCCAGGGCGTCAAGGGAGGGCTGGTGCCT
TCGGAGCCTCCCACTGCCGACCGCACAGCTCCCTCTCTGGGGGCTGAGGGACCCACCTGGCCCCTCCTCTGACACAGGGCTGGCCCGCCA
GGTGGCCTCCCAGCAAGCCAGCCTTTTTTGTAAGCAAATTTCTCCCCTTTATTGACCAATTAACTGAGCACTTGCTGCTATTTCTAGACA
TGAAATGTCACCTTGCTGAGGCCCAGCCCAGCCCAGCATAGCCCGAGGGCTGGAAAAACGCTTTCATCTCTAAAACTGAGAAATCATCAT
AATTGTGCTTTCACTTCCCAGGCTCCATGTGTCTTGGAGCCGTCACCCCGAGGCTCCCTCTTTAGGTCGGAGATTGGCCTTGCCTGTCGA
GGCAAGAGGCTGCAGAGGCGGGGACACACCTGTGTCCTCCGGGAGAGGCCCCCTCCTCTCCCCAGACCACAGGGGGCCTCTCTGCCTCCA
GCCCCACCTTCCCCGGGAGAAGCTTTCCCCAATCCCCAGGTCTCTAGATCATTCTGTTCTCGAGTATCCTGTGGAGGAGGCAAAAATGCC
TGGCGCCCCTTCTCTCCAAGCTCAATTCTCTAAGCCCCTCAGGGTCTCCTCCTCACCCCACCCCAGGCCCTTGGTGTCCAGGCTGCACCC
ACAGATGTCTGTTGCCAAACAGCCTGCCCTCCCTGCCGGAGCCGGCTCTGCCAGCCCCAGATTGGGAAGTCTCCCCGCTGGAGAAGGGTG
GGGCTCCTCTGAGCCTGCCCTGCCTCCTCCATCAGATCCTTTGGGAAGAAGTTTCTGGGAGATGCCCGCAGCTGTGCGTGCCCCAGACAC
AAAGGCTGGCCTGTGTGTAAGTCAAAGTCACTCCCGCAAACCTGAATCTCGAGCTACCTATTGGTTCTGTGAATGTTCTGTGTCTTTTAT

>80010_80010_2_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000290037_LHX3_chr9_139092599_ENST00000371748_length(amino acids)=1460AA_BP=0
MPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPL
VAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSG
CAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGV
PDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSAR
PQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADR
ANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKC
ESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQAS
SGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSL
PSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQE
DTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMF
SELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDA
YQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYAS
YYSSQYDYGEIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQ
DFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLD
MRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPS
GALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGG

--------------------------------------------------------------
>80010_80010_3_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000313050_LHX3_chr9_139092599_ENST00000371746_length(transcript)=6066nt_BP=3876nt
TCCAGCTCCAATTAAGGAACAGCTATATCCTGCTTCCTTCTGTAAGCAGCATCGACTTGTGCAAGGGTTCAGTCATGCAGCCACCGCCCC
AGACGGTCCCGTCTGGCATGGCTGGGCCACCTCCAGCCGGGAATCCTCGGAGCGTGTTCTGGGCTAGCAGCCCTTACAGGAGACGGGCTA
ATAATAATGCAGCAGTGGCTCCGACAACTTGCCCGTTGCAGCCGGTCACGGATCCATTTGCTTTTAGTAGACAGGCGCTCCAAAGTACAC
CACTGGGCAGTTCGTCCAAAAGCAGTCCACCTGTCTTGCAAGGCCCAGCCCCCGCAGGGTTTTCTCAGCACCCCGGTTTGCTTGTTCCTC
ACACACATGCCAGAGATAGCTCTCAGGGACCCTGTGAGCCCCTGCCTGGACCTCTGACACAGCCCAGAGCACATGCCAGTCCGTTTTCTG
GTGCATTGACACCTTCAGCACCTCCTGGGCCTGAGATGAACAGGAGTGCAGAGGTCGGTCCCAGTTCAGAGCCTGAAGTTCAGACTCTGC
CATATCTTCCTCACTACATTCCAGGAGTGGATCCTGAAACGTCTCATGGGGGCCACCCTCATGGGAACATGCCTGGGCTCGACCGACCCC
TGAGCAGGCAAAACCCACATGACGGTGTGGTCACCCCAGCAGCATCCCCTTCCCTCCCTCAGCCTGGTCTGCAGATGCCAGGACAGTGGG
GGCCAGTGCAGGGAGGCCCACAGCCCTCGGGGCAACATCGTTCACCCTGCCCTGAAGGACCTGTTCCCAGCGGGGTGCCCTGTGCCACCA
GCGTTCCTCATTTCCCCACCCCGTCCATCCTACATCAGGGCCCTGGTCATGAGCAACACAGCCCTCTGGTGGCTCCCCCAGCAGCCTTGC
CCAGTGACGGAAGAGACGAGGTGAGCCACTTGCAAAGTGGAAGCCACCTGGCCAATAACTCTGATCCTGAAAGTACATTCAGGCAAAATC
CCAGAATTGTGAATCACTGGGCAAGCCCAGAGCTCAGGCAGAATCCAGGAGTGAAGAATGAGCACCGGCCCGCCTCTGCTCTTGTGAACC
CCCTCGCCCGGGGAGATAGCCCAGAAAACCGTACGCACCACCCACTGGGGGCTGGGGCCGGGTCTGGCTGTGCCCCGCTAGAAGCAGACT
CAGGAGCTTCAGGAGCTCTGGCGATGTTTTTCCAAGGGGGAGAGACAGAAAATGAGGAGAATCTCTCATCTGAAAAAGCAGGCTTATCTG
GTCAAGCGGACTTTGACGATTTCTGCTCCAGCCCTGGGCTAGGCCGTCCGCCCGCACCTACACACGTGGGGGCAGGCAGCCTCTGCCAGG
CCCTTCTCCCAGGCCCCAGCAATGAGGCTGCTGGTGATGTGTGGGGTGACACAGCGAGCACAGGGGTGCCGGATGCCAGCGGCTCGCAGT
ATGAGAATGTTGAGAACTTAGAATTTGTTCAGAATCAAGAAGTTCTGCCAAGTGAGCCCCTCAATTTGGACCCTTCCTCCCCGAGTGACC
AGTTCAGATATGGGCCCCTTCCTGGGCCAGCTGTGCCCAGGCATGGTGCTGTGTGCCACACCGGAGCCCCTGATGCCACACTGCATACAG
TGCACCCTGACAGCGTGTCATCCAGCTATAGCAGCAGAAGCCACGGAAGGCTCTCAGGCTCAGCCAGGCCCCAGGAGCTGGTTGGCACAT
TCATTCAGCAAGAAGTTGGAAAACCCGAGGATGAAGCTTCAGGTAGTTTTTTTAAGCAAATCGATTCTTCTCCCGTAGGAGGTGAAACAG
ACGAGACCACTGTGAGCCAGAATTACCGTGGCAGCGTGTCCCAGCCCTCAACCCCGAGCCCCCCGAAACCTACAGGAATATTTCAGACAA
GTGCAAATAGTTCTTTCGAACCGGTAAAATCTCACTTAGTTGGGGTAAAACCATTTGAGGCAGATCGCGCCAACGTGGTTGGTGAAGTAA
GGGAGACCTGTGTCCGCCAGAAGCAGTGCAGACCAGCTGCCGCCCTGCCCGATGCTTCCCCTGGCAACCTGGAGCAGCCACCAGACAACA
TGGAGACCCTCTGTGCACCCCAGGTCTGTCCCCTGCCTCTTAACTCCACCACGGAAGCTGTGCACATGCTTCCGCACGCAGGGGCACCGC
CCTTGGATACTGTGTATCCAGCACCCGAGAAGAGGCCTTCAGCCAGGACCCAGGGGCCCGTGAAGTGTGAGAGCCCAGCAACGACTCTGT
GGGCGCAAAGTGAGCTGCCAGATTTTGGAGGCAACGTCCTTCTGGCCCCTGCAGCCCCGGCGCTTTATGTGTGTGCAAAACCTCAGCCAC
CTGTTGTTCAGCCTCCAGAAGAGGCGATGTCCGGGCAGCAGTCACGGAACCCAAGCTCGGCGGCCCCGGTGCAGAGCCGAGGTGGCATTG
GTGCTTCTGAGAACCTTGAGAATCCTCCCAAAATGGGAGAGGAGGAGGCCCTTCAGTCCCAGGCGAGTTCTGGTTATGCAAGTTTATTAT
CCTCACCGCCCACTGAGTCTCTGCAGAATCCTCCAGTCTTGATTGCTCAGCCTGATCACAGCTATAATCTGGCTCAGCCCATTAACTTTT
CTGTGTCCTTATCGAACTCTCATGAGAAGAATCAGTCCTGGAGAGAGGCTTTGGTGGGGGATAGACCTGCAGTCAGCAGTTGGGCTCTCG
GTGGTGATTCTGGGGAGAACACTTCTTTGTCTGGGATTCCAACCAGCTCTGTCCTTAGCTTGTCTCTGCCTAGCAGTGTTGCCCAAAGTA
ATTTTCCACAAGGTTCTGGTGCTTCCGAAATGGTTTCTAATCAGCCTGCTAATTTGCTGGTTCAACCACCATCCCAGCCAGTTCCAGAGA
ACTTGGTTCCAGAAAGTCAAAAGGATCGTAAGGCAGGAAGTGCTCTTCCCGGATTTGCTAATAGCCCTGCTGGAAGCACAAGTGTGGTGT
TAGTTCCACCTGCACACGGCACCCTGGTGCCTGATGGTAATAAGGCAAACCATTCCAGTCATCAGGAAGACACTTACGGAGCCCTAGACT
TTACCTTAAGCAGGACTTTGGAAAATCCTGTAAACGTGTACAACCCGTCCCATTCTGACAGCCTCGCTTCTCAGCAAAGTGTTGCCAGTC
ATCCCAGACAATCTGGGCCTGGGGCGCCTAACCTTGACCGTTTTTATCAGCAGGTCACGAAAGATGCCCAGGGCCAGCCTGGCCTCGAAA
GAGCCCAGCAGGAGCTGGTGCCACCCCAGCAACAGGCTTCTCCCCCACAACTACCCAAAGCCATGTTTTCGGAGCTGTCAAATCCAGAAA
GTCTGCCCGCACAGGGACAGGCCCAGAACTCAGCACAGTCACCAGCAAGTCTGGTTCTGGTCGACGCGGGTCAGCAGCTGCCCCCTCGGC
CTCCTCAGTCCTCTAGCGTGTCTCTGGTGTCCAGTGGCTCCGGCCAGGCAGCTGTGCCGTCAGAGCAGCCGTGGCCACAGCCAGTGCCTG
CACTTGCCCCCGGCCCACCGCCTCAGGACCTGGCCGCCTACTACTACTACCGGCCTTTGTACGATGCCTACCAGCCTCAGTACTCTTTGC
CGTACCCACCGGAGCCTGGCGCAGCCTCCCTCTATTACCAGGATGTCTACAGCCTCTATGAGCCTCGATACAGGCCCTATGATGGTGCTG
CGTCTGCTTACGCCCAGAACTACCGCTATCCCGAGCCCGAGCGGCCCAGCTCCCGAGCCAGCCACTCCTCGGAACGGCCACCTCCCAGGC
AAGGATATCCTGAAGGATACTATAGTTCCAAAAGTGGATGGAGCAGTCAGAGCGATTACTATGCAAGCTATTACTCCAGCCAGTACGATT
ATGGAGAGATCCCGCTGTGCGCTGGCTGTGACCAGCACATCCTGGACCGCTTCATCCTCAAGGCTCTGGACCGCCACTGGCACAGCAAGT
GTCTCAAGTGCAGCGACTGCCACACGCCACTGGCCGAGCGCTGCTTCAGCCGAGGGGAGAGCGTTTACTGCAAGGACGACTTTTTCAAGC
GCTTCGGGACCAAGTGCGCCGCGTGCCAGCTGGGCATCCCGCCCACGCAGGTGGTGCGCCGCGCCCAGGACTTCGTGTACCACCTGCACT
GCTTTGCCTGCGTCGTGTGCAAGCGGCAGCTGGCCACGGGCGACGAGTTCTACCTCATGGAGGACAGCCGGCTCGTGTGCAAGGCGGACT
ACGAAACCGCCAAGCAGCGAGAGGCCGAGGCCACGGCCAAGCGGCCGCGCACGACCATCACCGCCAAGCAGCTGGAGACGCTGAAGAGCG
CTTACAACACCTCGCCCAAGCCGGCGCGCCACGTGCGCGAGCAGCTCTCGTCCGAGACGGGCCTGGACATGCGCGTGGTGCAGGTTTGGT
TCCAGAACCGCCGGGCCAAGGAGAAGAGGCTGAAGAAGGACGCCGGCCGGCAGCGCTGGGGGCAGTATTTCCGCAACATGAAGCGCTCCC
GCGGCGGCTCCAAGTCGGACAAGGACAGCGTTCAGGAGGGGCAGGACAGCGACGCTGAGGTCTCCTTCCCCGATGAGCCTTCCTTGGCGG
AAATGGGCCCGGCCAATGGCCTCTACGGGAGCTTGGGGGAACCCACCCAGGCCTTGGGCCGGCCCTCGGGAGCCCTGGGCAACTTCTCCC
TGGAGCATGGAGGCCTGGCAGGCCCAGAGCAGTACCGAGAGCTGCGTCCCGGCAGCCCCTACGGTGTCCCCCCATCCCCCGCCGCCCCGC
AGAGCCTCCCTGGCCCCCAGCCCCTCCTCTCCAGCCTGGTGTACCCAGACACCAGCTTGGGCCTTGTGCCCTCGGGAGCCCCCGGCGGGC
CCCCACCCATGAGGGTGCTGGCAGGGAACGGACCCAGTTCTGACCTATCCACGGGGAGCAGCGGGGGTTACCCCGACTTCCCTGCCAGCC
CCGCCTCCTGGCTGGATGAGGTAGACCACGCTCAGTTCTGACCCAGGCCCGGCTCCACCCTGCACCTCACACGAGGGAGCTGCCCCTGGG
TGGGCGGCTCGGGGCTGCTGGGGTTTCCGAGGAAGTGGGGCCAGGGCGTCAAGGGAGGGCTGGTGCCTTCGGAGCCTCCCACTGCCGACC
GCACAGCTCCCTCTCTGGGGGCTGAGGGACCCACCTGGCCCCTCCTCTGACACAGGGCTGGCCCGCCAGGTGGCCTCCCAGCAAGCCAGC
CTTTTTTGTAAGCAAATTTCTCCCCTTTATTGACCAATTAACTGAGCACTTGCTGCTATTTCTAGACATGAAATGTCACCTTGCTGAGGC
CCAGCCCAGCCCAGCATAGCCCGAGGGCTGGAAAAACGCTTTCATCTCTAAAACTGAGAAATCATCATAATTGTGCTTTCACTTCCCAGG
CTCCATGTGTCTTGGAGCCGTCACCCCGAGGCTCCCTCTTTAGGTCGGAGATTGGCCTTGCCTGTCGAGGCAAGAGGCTGCAGAGGCGGG
GACACACCTGTGTCCTCCGGGAGAGGCCCCCTCCTCTCCCCAGACCACAGGGGGCCTCTCTGCCTCCAGCCCCACCTTCCCCGGGAGAAG
CTTTCCCCAATCCCCAGGTCTCTAGATCATTCTGTTCTCGAGTATCCTGTGGAGGAGGCAAAAATGCCTGGCGCCCCTTCTCTCCAAGCT
CAATTCTCTAAGCCCCTCAGGGTCTCCTCCTCACCCCACCCCAGGCCCTTGGTGTCCAGGCTGCACCCACAGATGTCTGTTGCCAAACAG
CCTGCCCTCCCTGCCGGAGCCGGCTCTGCCAGCCCCAGATTGGGAAGTCTCCCCGCTGGAGAAGGGTGGGGCTCCTCTGAGCCTGCCCTG
CCTCCTCCATCAGATCCTTTGGGAAGAAGTTTCTGGGAGATGCCCGCAGCTGTGCGTGCCCCAGACACAAAGGCTGGCCTGTGTGTAAGT
CAAAGTCACTCCCGCAAACCTGAATCTCGAGCTACCTATTGGTTCTGTGAATGTTCTGTGTCTTTTATTTATTCTCGGGTGATCAGCTCT

>80010_80010_3_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000313050_LHX3_chr9_139092599_ENST00000371746_length(amino acids)=1653AA_BP=1
MLPSVSSIDLCKGSVMQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQSTPLGSSSKSSP
PVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGV
DPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSI
LHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPEN
RTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEA
AGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSY
SSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVK
SHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPE
KRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPP
KMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSL
SGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLV
PDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQ
QQASPPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQD
LAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSS
KSGWSSQSDYYASYYSSQYDYGEIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQ
LGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPAR
HVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYG
SLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGN

--------------------------------------------------------------
>80010_80010_4_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000313050_LHX3_chr9_139092599_ENST00000371748_length(transcript)=6065nt_BP=3876nt
TCCAGCTCCAATTAAGGAACAGCTATATCCTGCTTCCTTCTGTAAGCAGCATCGACTTGTGCAAGGGTTCAGTCATGCAGCCACCGCCCC
AGACGGTCCCGTCTGGCATGGCTGGGCCACCTCCAGCCGGGAATCCTCGGAGCGTGTTCTGGGCTAGCAGCCCTTACAGGAGACGGGCTA
ATAATAATGCAGCAGTGGCTCCGACAACTTGCCCGTTGCAGCCGGTCACGGATCCATTTGCTTTTAGTAGACAGGCGCTCCAAAGTACAC
CACTGGGCAGTTCGTCCAAAAGCAGTCCACCTGTCTTGCAAGGCCCAGCCCCCGCAGGGTTTTCTCAGCACCCCGGTTTGCTTGTTCCTC
ACACACATGCCAGAGATAGCTCTCAGGGACCCTGTGAGCCCCTGCCTGGACCTCTGACACAGCCCAGAGCACATGCCAGTCCGTTTTCTG
GTGCATTGACACCTTCAGCACCTCCTGGGCCTGAGATGAACAGGAGTGCAGAGGTCGGTCCCAGTTCAGAGCCTGAAGTTCAGACTCTGC
CATATCTTCCTCACTACATTCCAGGAGTGGATCCTGAAACGTCTCATGGGGGCCACCCTCATGGGAACATGCCTGGGCTCGACCGACCCC
TGAGCAGGCAAAACCCACATGACGGTGTGGTCACCCCAGCAGCATCCCCTTCCCTCCCTCAGCCTGGTCTGCAGATGCCAGGACAGTGGG
GGCCAGTGCAGGGAGGCCCACAGCCCTCGGGGCAACATCGTTCACCCTGCCCTGAAGGACCTGTTCCCAGCGGGGTGCCCTGTGCCACCA
GCGTTCCTCATTTCCCCACCCCGTCCATCCTACATCAGGGCCCTGGTCATGAGCAACACAGCCCTCTGGTGGCTCCCCCAGCAGCCTTGC
CCAGTGACGGAAGAGACGAGGTGAGCCACTTGCAAAGTGGAAGCCACCTGGCCAATAACTCTGATCCTGAAAGTACATTCAGGCAAAATC
CCAGAATTGTGAATCACTGGGCAAGCCCAGAGCTCAGGCAGAATCCAGGAGTGAAGAATGAGCACCGGCCCGCCTCTGCTCTTGTGAACC
CCCTCGCCCGGGGAGATAGCCCAGAAAACCGTACGCACCACCCACTGGGGGCTGGGGCCGGGTCTGGCTGTGCCCCGCTAGAAGCAGACT
CAGGAGCTTCAGGAGCTCTGGCGATGTTTTTCCAAGGGGGAGAGACAGAAAATGAGGAGAATCTCTCATCTGAAAAAGCAGGCTTATCTG
GTCAAGCGGACTTTGACGATTTCTGCTCCAGCCCTGGGCTAGGCCGTCCGCCCGCACCTACACACGTGGGGGCAGGCAGCCTCTGCCAGG
CCCTTCTCCCAGGCCCCAGCAATGAGGCTGCTGGTGATGTGTGGGGTGACACAGCGAGCACAGGGGTGCCGGATGCCAGCGGCTCGCAGT
ATGAGAATGTTGAGAACTTAGAATTTGTTCAGAATCAAGAAGTTCTGCCAAGTGAGCCCCTCAATTTGGACCCTTCCTCCCCGAGTGACC
AGTTCAGATATGGGCCCCTTCCTGGGCCAGCTGTGCCCAGGCATGGTGCTGTGTGCCACACCGGAGCCCCTGATGCCACACTGCATACAG
TGCACCCTGACAGCGTGTCATCCAGCTATAGCAGCAGAAGCCACGGAAGGCTCTCAGGCTCAGCCAGGCCCCAGGAGCTGGTTGGCACAT
TCATTCAGCAAGAAGTTGGAAAACCCGAGGATGAAGCTTCAGGTAGTTTTTTTAAGCAAATCGATTCTTCTCCCGTAGGAGGTGAAACAG
ACGAGACCACTGTGAGCCAGAATTACCGTGGCAGCGTGTCCCAGCCCTCAACCCCGAGCCCCCCGAAACCTACAGGAATATTTCAGACAA
GTGCAAATAGTTCTTTCGAACCGGTAAAATCTCACTTAGTTGGGGTAAAACCATTTGAGGCAGATCGCGCCAACGTGGTTGGTGAAGTAA
GGGAGACCTGTGTCCGCCAGAAGCAGTGCAGACCAGCTGCCGCCCTGCCCGATGCTTCCCCTGGCAACCTGGAGCAGCCACCAGACAACA
TGGAGACCCTCTGTGCACCCCAGGTCTGTCCCCTGCCTCTTAACTCCACCACGGAAGCTGTGCACATGCTTCCGCACGCAGGGGCACCGC
CCTTGGATACTGTGTATCCAGCACCCGAGAAGAGGCCTTCAGCCAGGACCCAGGGGCCCGTGAAGTGTGAGAGCCCAGCAACGACTCTGT
GGGCGCAAAGTGAGCTGCCAGATTTTGGAGGCAACGTCCTTCTGGCCCCTGCAGCCCCGGCGCTTTATGTGTGTGCAAAACCTCAGCCAC
CTGTTGTTCAGCCTCCAGAAGAGGCGATGTCCGGGCAGCAGTCACGGAACCCAAGCTCGGCGGCCCCGGTGCAGAGCCGAGGTGGCATTG
GTGCTTCTGAGAACCTTGAGAATCCTCCCAAAATGGGAGAGGAGGAGGCCCTTCAGTCCCAGGCGAGTTCTGGTTATGCAAGTTTATTAT
CCTCACCGCCCACTGAGTCTCTGCAGAATCCTCCAGTCTTGATTGCTCAGCCTGATCACAGCTATAATCTGGCTCAGCCCATTAACTTTT
CTGTGTCCTTATCGAACTCTCATGAGAAGAATCAGTCCTGGAGAGAGGCTTTGGTGGGGGATAGACCTGCAGTCAGCAGTTGGGCTCTCG
GTGGTGATTCTGGGGAGAACACTTCTTTGTCTGGGATTCCAACCAGCTCTGTCCTTAGCTTGTCTCTGCCTAGCAGTGTTGCCCAAAGTA
ATTTTCCACAAGGTTCTGGTGCTTCCGAAATGGTTTCTAATCAGCCTGCTAATTTGCTGGTTCAACCACCATCCCAGCCAGTTCCAGAGA
ACTTGGTTCCAGAAAGTCAAAAGGATCGTAAGGCAGGAAGTGCTCTTCCCGGATTTGCTAATAGCCCTGCTGGAAGCACAAGTGTGGTGT
TAGTTCCACCTGCACACGGCACCCTGGTGCCTGATGGTAATAAGGCAAACCATTCCAGTCATCAGGAAGACACTTACGGAGCCCTAGACT
TTACCTTAAGCAGGACTTTGGAAAATCCTGTAAACGTGTACAACCCGTCCCATTCTGACAGCCTCGCTTCTCAGCAAAGTGTTGCCAGTC
ATCCCAGACAATCTGGGCCTGGGGCGCCTAACCTTGACCGTTTTTATCAGCAGGTCACGAAAGATGCCCAGGGCCAGCCTGGCCTCGAAA
GAGCCCAGCAGGAGCTGGTGCCACCCCAGCAACAGGCTTCTCCCCCACAACTACCCAAAGCCATGTTTTCGGAGCTGTCAAATCCAGAAA
GTCTGCCCGCACAGGGACAGGCCCAGAACTCAGCACAGTCACCAGCAAGTCTGGTTCTGGTCGACGCGGGTCAGCAGCTGCCCCCTCGGC
CTCCTCAGTCCTCTAGCGTGTCTCTGGTGTCCAGTGGCTCCGGCCAGGCAGCTGTGCCGTCAGAGCAGCCGTGGCCACAGCCAGTGCCTG
CACTTGCCCCCGGCCCACCGCCTCAGGACCTGGCCGCCTACTACTACTACCGGCCTTTGTACGATGCCTACCAGCCTCAGTACTCTTTGC
CGTACCCACCGGAGCCTGGCGCAGCCTCCCTCTATTACCAGGATGTCTACAGCCTCTATGAGCCTCGATACAGGCCCTATGATGGTGCTG
CGTCTGCTTACGCCCAGAACTACCGCTATCCCGAGCCCGAGCGGCCCAGCTCCCGAGCCAGCCACTCCTCGGAACGGCCACCTCCCAGGC
AAGGATATCCTGAAGGATACTATAGTTCCAAAAGTGGATGGAGCAGTCAGAGCGATTACTATGCAAGCTATTACTCCAGCCAGTACGATT
ATGGAGAGATCCCGCTGTGCGCTGGCTGTGACCAGCACATCCTGGACCGCTTCATCCTCAAGGCTCTGGACCGCCACTGGCACAGCAAGT
GTCTCAAGTGCAGCGACTGCCACACGCCACTGGCCGAGCGCTGCTTCAGCCGAGGGGAGAGCGTTTACTGCAAGGACGACTTTTTCAAGC
GCTTCGGGACCAAGTGCGCCGCGTGCCAGCTGGGCATCCCGCCCACGCAGGTGGTGCGCCGCGCCCAGGACTTCGTGTACCACCTGCACT
GCTTTGCCTGCGTCGTGTGCAAGCGGCAGCTGGCCACGGGCGACGAGTTCTACCTCATGGAGGACAGCCGGCTCGTGTGCAAGGCGGACT
ACGAAACCGCCAAGCAGCGAGAGGCCGAGGCCACGGCCAAGCGGCCGCGCACGACCATCACCGCCAAGCAGCTGGAGACGCTGAAGAGCG
CTTACAACACCTCGCCCAAGCCGGCGCGCCACGTGCGCGAGCAGCTCTCGTCCGAGACGGGCCTGGACATGCGCGTGGTGCAGGTTTGGT
TCCAGAACCGCCGGGCCAAGGAGAAGAGGCTGAAGAAGGACGCCGGCCGGCAGCGCTGGGGGCAGTATTTCCGCAACATGAAGCGCTCCC
GCGGCGGCTCCAAGTCGGACAAGGACAGCGTTCAGGAGGGGCAGGACAGCGACGCTGAGGTCTCCTTCCCCGATGAGCCTTCCTTGGCGG
AAATGGGCCCGGCCAATGGCCTCTACGGGAGCTTGGGGGAACCCACCCAGGCCTTGGGCCGGCCCTCGGGAGCCCTGGGCAACTTCTCCC
TGGAGCATGGAGGCCTGGCAGGCCCAGAGCAGTACCGAGAGCTGCGTCCCGGCAGCCCCTACGGTGTCCCCCCATCCCCCGCCGCCCCGC
AGAGCCTCCCTGGCCCCCAGCCCCTCCTCTCCAGCCTGGTGTACCCAGACACCAGCTTGGGCCTTGTGCCCTCGGGAGCCCCCGGCGGGC
CCCCACCCATGAGGGTGCTGGCAGGGAACGGACCCAGTTCTGACCTATCCACGGGGAGCAGCGGGGGTTACCCCGACTTCCCTGCCAGCC
CCGCCTCCTGGCTGGATGAGGTAGACCACGCTCAGTTCTGACCCAGGCCCGGCTCCACCCTGCACCTCACACGAGGGAGCTGCCCCTGGG
TGGGCGGCTCGGGGCTGCTGGGGTTTCCGAGGAAGTGGGGCCAGGGCGTCAAGGGAGGGCTGGTGCCTTCGGAGCCTCCCACTGCCGACC
GCACAGCTCCCTCTCTGGGGGCTGAGGGACCCACCTGGCCCCTCCTCTGACACAGGGCTGGCCCGCCAGGTGGCCTCCCAGCAAGCCAGC
CTTTTTTGTAAGCAAATTTCTCCCCTTTATTGACCAATTAACTGAGCACTTGCTGCTATTTCTAGACATGAAATGTCACCTTGCTGAGGC
CCAGCCCAGCCCAGCATAGCCCGAGGGCTGGAAAAACGCTTTCATCTCTAAAACTGAGAAATCATCATAATTGTGCTTTCACTTCCCAGG
CTCCATGTGTCTTGGAGCCGTCACCCCGAGGCTCCCTCTTTAGGTCGGAGATTGGCCTTGCCTGTCGAGGCAAGAGGCTGCAGAGGCGGG
GACACACCTGTGTCCTCCGGGAGAGGCCCCCTCCTCTCCCCAGACCACAGGGGGCCTCTCTGCCTCCAGCCCCACCTTCCCCGGGAGAAG
CTTTCCCCAATCCCCAGGTCTCTAGATCATTCTGTTCTCGAGTATCCTGTGGAGGAGGCAAAAATGCCTGGCGCCCCTTCTCTCCAAGCT
CAATTCTCTAAGCCCCTCAGGGTCTCCTCCTCACCCCACCCCAGGCCCTTGGTGTCCAGGCTGCACCCACAGATGTCTGTTGCCAAACAG
CCTGCCCTCCCTGCCGGAGCCGGCTCTGCCAGCCCCAGATTGGGAAGTCTCCCCGCTGGAGAAGGGTGGGGCTCCTCTGAGCCTGCCCTG
CCTCCTCCATCAGATCCTTTGGGAAGAAGTTTCTGGGAGATGCCCGCAGCTGTGCGTGCCCCAGACACAAAGGCTGGCCTGTGTGTAAGT
CAAAGTCACTCCCGCAAACCTGAATCTCGAGCTACCTATTGGTTCTGTGAATGTTCTGTGTCTTTTATTTATTCTCGGGTGATCAGCTCT

>80010_80010_4_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000313050_LHX3_chr9_139092599_ENST00000371748_length(amino acids)=1653AA_BP=1
MLPSVSSIDLCKGSVMQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQSTPLGSSSKSSP
PVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGV
DPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSI
LHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPEN
RTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEA
AGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSY
SSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVK
SHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPE
KRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPP
KMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSL
SGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLV
PDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQ
QQASPPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQD
LAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSS
KSGWSSQSDYYASYYSSQYDYGEIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQ
LGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPAR
HVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYG
SLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGN

--------------------------------------------------------------
>80010_80010_5_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000371706_LHX3_chr9_139092599_ENST00000371746_length(transcript)=5492nt_BP=3302nt
TGAAACGTCTCATGGGGGCCACCCTCATGGGAACATGCCTGGGCTCGACCGACCCCTGAGCAGGCAAAACCCACATGACGGTGTGGTCAC
CCCAGCAGCATCCCCTTCCCTCCCTCAGCCTGGTCTGCAGATGCCAGGACAGTGGGGGCCAGTGCAGGGAGGCCCACAGCCCTCGGGGCA
ACATCGTTCACCCTGCCCTGAAGGACCTGTTCCCAGCGGGGTGCCCTGTGCCACCAGCGTTCCTCATTTCCCCACCCCGTCCATCCTACA
TCAGGGCCCTGGTCATGAGCAACACAGCCCTCTGGTGGCTCCCCCAGCAGCCTTGCCCAGTGACGGAAGAGACGAGGTGAGCCACTTGCA
AAGTGGAAGCCACCTGGCCAATAACTCTGATCCTGAAAGTACATTCAGGCAAAATCCCAGAATTGTGAATCACTGGGCAAGCCCAGAGCT
CAGGCAGAATCCAGGAGTGAAGAATGAGCACCGGCCCGCCTCTGCTCTTGTGAACCCCCTCGCCCGGGGAGATAGCCCAGAAAACCGTAC
GCACCACCCACTGGGGGCTGGGGCCGGGTCTGGCTGTGCCCCGCTAGAAGCAGACTCAGGAGCTTCAGGAGCTCTGGCGATGTTTTTCCA
AGGGGGAGAGACAGAAAATGAGGAGAATCTCTCATCTGAAAAAGCAGGCTTATCTGGTCAAGCGGACTTTGACGATTTCTGCTCCAGCCC
TGGGCTAGGCCGTCCGCCCGCACCTACACACGTGGGGGCAGGCAGCCTCTGCCAGGCCCTTCTCCCAGGCCCCAGCAATGAGGCTGCTGG
TGATGTGTGGGGTGACACAGCGAGCACAGGGGTGCCGGATGCCAGCGGCTCGCAGTATGAGAATGTTGAGAACTTAGAATTTGTTCAGAA
TCAAGAAGTTCTGCCAAGTGAGCCCCTCAATTTGGACCCTTCCTCCCCGAGTGACCAGTTCAGATATGGGCCCCTTCCTGGGCCAGCTGT
GCCCAGGCATGGTGCTGTGTGCCACACCGGAGCCCCTGATGCCACACTGCATACAGTGCACCCTGACAGCGTGTCATCCAGCTATAGCAG
CAGAAGCCACGGAAGGCTCTCAGGCTCAGCCAGGCCCCAGGAGCTGGTTGGCACATTCATTCAGCAAGAAGTTGGAAAACCCGAGGATGA
AGCTTCAGGTAGTTTTTTTAAGCAAATCGATTCTTCTCCCGTAGGAGGTGAAACAGACGAGACCACTGTGAGCCAGAATTACCGTGGCAG
CGTGTCCCAGCCCTCAACCCCGAGCCCCCCGAAACCTACAGGAATATTTCAGACAAGTGCAAATAGTTCTTTCGAACCGGTAAAATCTCA
CTTAGTTGGGGTAAAACCATTTGAGGCAGATCGCGCCAACGTGGTTGGTGAAGTAAGGGAGACCTGTGTCCGCCAGAAGCAGTGCAGACC
AGCTGCCGCCCTGCCCGATGCTTCCCCTGGCAACCTGGAGCAGCCACCAGACAACATGGAGACCCTCTGTGCACCCCAGGTCTGTCCCCT
GCCTCTTAACTCCACCACGGAAGCTGTGCACATGCTTCCGCACGCAGGGGCACCGCCCTTGGATACTGTGTATCCAGCACCCGAGAAGAG
GCCTTCAGCCAGGACCCAGGGGCCCGTGAAGTGTGAGAGCCCAGCAACGACTCTGTGGGCGCAAAGTGAGCTGCCAGATTTTGGAGGCAA
CGTCCTTCTGGCCCCTGCAGCCCCGGCGCTTTATGTGTGTGCAAAACCTCAGCCACCTGTTGTTCAGCCTCCAGAAGAGGCGATGTCCGG
GCAGCAGTCACGGAACCCAAGCTCGGCGGCCCCGGTGCAGAGCCGAGGTGGCATTGGTGCTTCTGAGAACCTTGAGAATCCTCCCAAAAT
GGGAGAGGAGGAGGCCCTTCAGTCCCAGGCGAGTTCTGGTTATGCAAGTTTATTATCCTCACCGCCCACTGAGTCTCTGCAGAATCCTCC
AGTCTTGATTGCTCAGCCTGATCACAGCTATAATCTGGCTCAGCCCATTAACTTTTCTGTGTCCTTATCGAACTCTCATGAGAAGAATCA
GTCCTGGAGAGAGGCTTTGGTGGGGGATAGACCTGCAGTCAGCAGTTGGGCTCTCGGTGGTGATTCTGGGGAGAACACTTCTTTGTCTGG
GATTCCAACCAGCTCTGTCCTTAGCTTGTCTCTGCCTAGCAGTGTTGCCCAAAGTAATTTTCCACAAGGTTCTGGTGCTTCCGAAATGGT
TTCTAATCAGCCTGCTAATTTGCTGGTTCAACCACCATCCCAGCCAGTTCCAGAGAACTTGGTTCCAGAAAGTCAAAAGGATCGTAAGGC
AGGAAGTGCTCTTCCCGGATTTGCTAATAGCCCTGCTGGAAGCACAAGTGTGGTGTTAGTTCCACCTGCACACGGCACCCTGGTGCCTGA
TGGTAATAAGGCAAACCATTCCAGTCATCAGGAAGACACTTACGGAGCCCTAGACTTTACCTTAAGCAGGACTTTGGAAAATCCTGTAAA
CGTGTACAACCCGTCCCATTCTGACAGCCTCGCTTCTCAGCAAAGTGTTGCCAGTCATCCCAGACAATCTGGGCCTGGGGCGCCTAACCT
TGACCGTTTTTATCAGCAGGTCACGAAAGATGCCCAGGGCCAGCCTGGCCTCGAAAGAGCCCAGCAGGAGCTGGTGCCACCCCAGCAACA
GGCTTCTCCCCCACAACTACCCAAAGCCATGTTTTCGGAGCTGTCAAATCCAGAAAGTCTGCCCGCACAGGGACAGGCCCAGAACTCAGC
ACAGTCACCAGCAAGTCTGGTTCTGGTCGACGCGGGTCAGCAGCTGCCCCCTCGGCCTCCTCAGTCCTCTAGCGTGTCTCTGGTGTCCAG
TGGCTCCGGCCAGGCAGCTGTGCCGTCAGAGCAGCCGTGGCCACAGCCAGTGCCTGCACTTGCCCCCGGCCCACCGCCTCAGGACCTGGC
CGCCTACTACTACTACCGGCCTTTGTACGATGCCTACCAGCCTCAGTACTCTTTGCCGTACCCACCGGAGCCTGGCGCAGCCTCCCTCTA
TTACCAGGATGTCTACAGCCTCTATGAGCCTCGATACAGGCCCTATGATGGTGCTGCGTCTGCTTACGCCCAGAACTACCGCTATCCCGA
GCCCGAGCGGCCCAGCTCCCGAGCCAGCCACTCCTCGGAACGGCCACCTCCCAGGCAAGGATATCCTGAAGGATACTATAGTTCCAAAAG
TGGATGGAGCAGTCAGAGCGATTACTATGCAAGCTATTACTCCAGCCAGTACGATTATGGAGAGATCCCGCTGTGCGCTGGCTGTGACCA
GCACATCCTGGACCGCTTCATCCTCAAGGCTCTGGACCGCCACTGGCACAGCAAGTGTCTCAAGTGCAGCGACTGCCACACGCCACTGGC
CGAGCGCTGCTTCAGCCGAGGGGAGAGCGTTTACTGCAAGGACGACTTTTTCAAGCGCTTCGGGACCAAGTGCGCCGCGTGCCAGCTGGG
CATCCCGCCCACGCAGGTGGTGCGCCGCGCCCAGGACTTCGTGTACCACCTGCACTGCTTTGCCTGCGTCGTGTGCAAGCGGCAGCTGGC
CACGGGCGACGAGTTCTACCTCATGGAGGACAGCCGGCTCGTGTGCAAGGCGGACTACGAAACCGCCAAGCAGCGAGAGGCCGAGGCCAC
GGCCAAGCGGCCGCGCACGACCATCACCGCCAAGCAGCTGGAGACGCTGAAGAGCGCTTACAACACCTCGCCCAAGCCGGCGCGCCACGT
GCGCGAGCAGCTCTCGTCCGAGACGGGCCTGGACATGCGCGTGGTGCAGGTTTGGTTCCAGAACCGCCGGGCCAAGGAGAAGAGGCTGAA
GAAGGACGCCGGCCGGCAGCGCTGGGGGCAGTATTTCCGCAACATGAAGCGCTCCCGCGGCGGCTCCAAGTCGGACAAGGACAGCGTTCA
GGAGGGGCAGGACAGCGACGCTGAGGTCTCCTTCCCCGATGAGCCTTCCTTGGCGGAAATGGGCCCGGCCAATGGCCTCTACGGGAGCTT
GGGGGAACCCACCCAGGCCTTGGGCCGGCCCTCGGGAGCCCTGGGCAACTTCTCCCTGGAGCATGGAGGCCTGGCAGGCCCAGAGCAGTA
CCGAGAGCTGCGTCCCGGCAGCCCCTACGGTGTCCCCCCATCCCCCGCCGCCCCGCAGAGCCTCCCTGGCCCCCAGCCCCTCCTCTCCAG
CCTGGTGTACCCAGACACCAGCTTGGGCCTTGTGCCCTCGGGAGCCCCCGGCGGGCCCCCACCCATGAGGGTGCTGGCAGGGAACGGACC
CAGTTCTGACCTATCCACGGGGAGCAGCGGGGGTTACCCCGACTTCCCTGCCAGCCCCGCCTCCTGGCTGGATGAGGTAGACCACGCTCA
GTTCTGACCCAGGCCCGGCTCCACCCTGCACCTCACACGAGGGAGCTGCCCCTGGGTGGGCGGCTCGGGGCTGCTGGGGTTTCCGAGGAA
GTGGGGCCAGGGCGTCAAGGGAGGGCTGGTGCCTTCGGAGCCTCCCACTGCCGACCGCACAGCTCCCTCTCTGGGGGCTGAGGGACCCAC
CTGGCCCCTCCTCTGACACAGGGCTGGCCCGCCAGGTGGCCTCCCAGCAAGCCAGCCTTTTTTGTAAGCAAATTTCTCCCCTTTATTGAC
CAATTAACTGAGCACTTGCTGCTATTTCTAGACATGAAATGTCACCTTGCTGAGGCCCAGCCCAGCCCAGCATAGCCCGAGGGCTGGAAA
AACGCTTTCATCTCTAAAACTGAGAAATCATCATAATTGTGCTTTCACTTCCCAGGCTCCATGTGTCTTGGAGCCGTCACCCCGAGGCTC
CCTCTTTAGGTCGGAGATTGGCCTTGCCTGTCGAGGCAAGAGGCTGCAGAGGCGGGGACACACCTGTGTCCTCCGGGAGAGGCCCCCTCC
TCTCCCCAGACCACAGGGGGCCTCTCTGCCTCCAGCCCCACCTTCCCCGGGAGAAGCTTTCCCCAATCCCCAGGTCTCTAGATCATTCTG
TTCTCGAGTATCCTGTGGAGGAGGCAAAAATGCCTGGCGCCCCTTCTCTCCAAGCTCAATTCTCTAAGCCCCTCAGGGTCTCCTCCTCAC
CCCACCCCAGGCCCTTGGTGTCCAGGCTGCACCCACAGATGTCTGTTGCCAAACAGCCTGCCCTCCCTGCCGGAGCCGGCTCTGCCAGCC
CCAGATTGGGAAGTCTCCCCGCTGGAGAAGGGTGGGGCTCCTCTGAGCCTGCCCTGCCTCCTCCATCAGATCCTTTGGGAAGAAGTTTCT
GGGAGATGCCCGCAGCTGTGCGTGCCCCAGACACAAAGGCTGGCCTGTGTGTAAGTCAAAGTCACTCCCGCAAACCTGAATCTCGAGCTA
CCTATTGGTTCTGTGAATGTTCTGTGTCTTTTATTTATTCTCGGGTGATCAGCTCTTTCCAAGACTTCAATAAATTTGTCAGTTACAGTC

>80010_80010_5_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000371706_LHX3_chr9_139092599_ENST00000371746_length(amino acids)=1460AA_BP=0
MPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPL
VAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSG
CAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGV
PDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSAR
PQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADR
ANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKC
ESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQAS
SGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSL
PSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQE
DTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMF
SELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDA
YQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYAS
YYSSQYDYGEIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQ
DFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLD
MRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPS
GALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGG

--------------------------------------------------------------
>80010_80010_6_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000371706_LHX3_chr9_139092599_ENST00000371748_length(transcript)=5491nt_BP=3302nt
TGAAACGTCTCATGGGGGCCACCCTCATGGGAACATGCCTGGGCTCGACCGACCCCTGAGCAGGCAAAACCCACATGACGGTGTGGTCAC
CCCAGCAGCATCCCCTTCCCTCCCTCAGCCTGGTCTGCAGATGCCAGGACAGTGGGGGCCAGTGCAGGGAGGCCCACAGCCCTCGGGGCA
ACATCGTTCACCCTGCCCTGAAGGACCTGTTCCCAGCGGGGTGCCCTGTGCCACCAGCGTTCCTCATTTCCCCACCCCGTCCATCCTACA
TCAGGGCCCTGGTCATGAGCAACACAGCCCTCTGGTGGCTCCCCCAGCAGCCTTGCCCAGTGACGGAAGAGACGAGGTGAGCCACTTGCA
AAGTGGAAGCCACCTGGCCAATAACTCTGATCCTGAAAGTACATTCAGGCAAAATCCCAGAATTGTGAATCACTGGGCAAGCCCAGAGCT
CAGGCAGAATCCAGGAGTGAAGAATGAGCACCGGCCCGCCTCTGCTCTTGTGAACCCCCTCGCCCGGGGAGATAGCCCAGAAAACCGTAC
GCACCACCCACTGGGGGCTGGGGCCGGGTCTGGCTGTGCCCCGCTAGAAGCAGACTCAGGAGCTTCAGGAGCTCTGGCGATGTTTTTCCA
AGGGGGAGAGACAGAAAATGAGGAGAATCTCTCATCTGAAAAAGCAGGCTTATCTGGTCAAGCGGACTTTGACGATTTCTGCTCCAGCCC
TGGGCTAGGCCGTCCGCCCGCACCTACACACGTGGGGGCAGGCAGCCTCTGCCAGGCCCTTCTCCCAGGCCCCAGCAATGAGGCTGCTGG
TGATGTGTGGGGTGACACAGCGAGCACAGGGGTGCCGGATGCCAGCGGCTCGCAGTATGAGAATGTTGAGAACTTAGAATTTGTTCAGAA
TCAAGAAGTTCTGCCAAGTGAGCCCCTCAATTTGGACCCTTCCTCCCCGAGTGACCAGTTCAGATATGGGCCCCTTCCTGGGCCAGCTGT
GCCCAGGCATGGTGCTGTGTGCCACACCGGAGCCCCTGATGCCACACTGCATACAGTGCACCCTGACAGCGTGTCATCCAGCTATAGCAG
CAGAAGCCACGGAAGGCTCTCAGGCTCAGCCAGGCCCCAGGAGCTGGTTGGCACATTCATTCAGCAAGAAGTTGGAAAACCCGAGGATGA
AGCTTCAGGTAGTTTTTTTAAGCAAATCGATTCTTCTCCCGTAGGAGGTGAAACAGACGAGACCACTGTGAGCCAGAATTACCGTGGCAG
CGTGTCCCAGCCCTCAACCCCGAGCCCCCCGAAACCTACAGGAATATTTCAGACAAGTGCAAATAGTTCTTTCGAACCGGTAAAATCTCA
CTTAGTTGGGGTAAAACCATTTGAGGCAGATCGCGCCAACGTGGTTGGTGAAGTAAGGGAGACCTGTGTCCGCCAGAAGCAGTGCAGACC
AGCTGCCGCCCTGCCCGATGCTTCCCCTGGCAACCTGGAGCAGCCACCAGACAACATGGAGACCCTCTGTGCACCCCAGGTCTGTCCCCT
GCCTCTTAACTCCACCACGGAAGCTGTGCACATGCTTCCGCACGCAGGGGCACCGCCCTTGGATACTGTGTATCCAGCACCCGAGAAGAG
GCCTTCAGCCAGGACCCAGGGGCCCGTGAAGTGTGAGAGCCCAGCAACGACTCTGTGGGCGCAAAGTGAGCTGCCAGATTTTGGAGGCAA
CGTCCTTCTGGCCCCTGCAGCCCCGGCGCTTTATGTGTGTGCAAAACCTCAGCCACCTGTTGTTCAGCCTCCAGAAGAGGCGATGTCCGG
GCAGCAGTCACGGAACCCAAGCTCGGCGGCCCCGGTGCAGAGCCGAGGTGGCATTGGTGCTTCTGAGAACCTTGAGAATCCTCCCAAAAT
GGGAGAGGAGGAGGCCCTTCAGTCCCAGGCGAGTTCTGGTTATGCAAGTTTATTATCCTCACCGCCCACTGAGTCTCTGCAGAATCCTCC
AGTCTTGATTGCTCAGCCTGATCACAGCTATAATCTGGCTCAGCCCATTAACTTTTCTGTGTCCTTATCGAACTCTCATGAGAAGAATCA
GTCCTGGAGAGAGGCTTTGGTGGGGGATAGACCTGCAGTCAGCAGTTGGGCTCTCGGTGGTGATTCTGGGGAGAACACTTCTTTGTCTGG
GATTCCAACCAGCTCTGTCCTTAGCTTGTCTCTGCCTAGCAGTGTTGCCCAAAGTAATTTTCCACAAGGTTCTGGTGCTTCCGAAATGGT
TTCTAATCAGCCTGCTAATTTGCTGGTTCAACCACCATCCCAGCCAGTTCCAGAGAACTTGGTTCCAGAAAGTCAAAAGGATCGTAAGGC
AGGAAGTGCTCTTCCCGGATTTGCTAATAGCCCTGCTGGAAGCACAAGTGTGGTGTTAGTTCCACCTGCACACGGCACCCTGGTGCCTGA
TGGTAATAAGGCAAACCATTCCAGTCATCAGGAAGACACTTACGGAGCCCTAGACTTTACCTTAAGCAGGACTTTGGAAAATCCTGTAAA
CGTGTACAACCCGTCCCATTCTGACAGCCTCGCTTCTCAGCAAAGTGTTGCCAGTCATCCCAGACAATCTGGGCCTGGGGCGCCTAACCT
TGACCGTTTTTATCAGCAGGTCACGAAAGATGCCCAGGGCCAGCCTGGCCTCGAAAGAGCCCAGCAGGAGCTGGTGCCACCCCAGCAACA
GGCTTCTCCCCCACAACTACCCAAAGCCATGTTTTCGGAGCTGTCAAATCCAGAAAGTCTGCCCGCACAGGGACAGGCCCAGAACTCAGC
ACAGTCACCAGCAAGTCTGGTTCTGGTCGACGCGGGTCAGCAGCTGCCCCCTCGGCCTCCTCAGTCCTCTAGCGTGTCTCTGGTGTCCAG
TGGCTCCGGCCAGGCAGCTGTGCCGTCAGAGCAGCCGTGGCCACAGCCAGTGCCTGCACTTGCCCCCGGCCCACCGCCTCAGGACCTGGC
CGCCTACTACTACTACCGGCCTTTGTACGATGCCTACCAGCCTCAGTACTCTTTGCCGTACCCACCGGAGCCTGGCGCAGCCTCCCTCTA
TTACCAGGATGTCTACAGCCTCTATGAGCCTCGATACAGGCCCTATGATGGTGCTGCGTCTGCTTACGCCCAGAACTACCGCTATCCCGA
GCCCGAGCGGCCCAGCTCCCGAGCCAGCCACTCCTCGGAACGGCCACCTCCCAGGCAAGGATATCCTGAAGGATACTATAGTTCCAAAAG
TGGATGGAGCAGTCAGAGCGATTACTATGCAAGCTATTACTCCAGCCAGTACGATTATGGAGAGATCCCGCTGTGCGCTGGCTGTGACCA
GCACATCCTGGACCGCTTCATCCTCAAGGCTCTGGACCGCCACTGGCACAGCAAGTGTCTCAAGTGCAGCGACTGCCACACGCCACTGGC
CGAGCGCTGCTTCAGCCGAGGGGAGAGCGTTTACTGCAAGGACGACTTTTTCAAGCGCTTCGGGACCAAGTGCGCCGCGTGCCAGCTGGG
CATCCCGCCCACGCAGGTGGTGCGCCGCGCCCAGGACTTCGTGTACCACCTGCACTGCTTTGCCTGCGTCGTGTGCAAGCGGCAGCTGGC
CACGGGCGACGAGTTCTACCTCATGGAGGACAGCCGGCTCGTGTGCAAGGCGGACTACGAAACCGCCAAGCAGCGAGAGGCCGAGGCCAC
GGCCAAGCGGCCGCGCACGACCATCACCGCCAAGCAGCTGGAGACGCTGAAGAGCGCTTACAACACCTCGCCCAAGCCGGCGCGCCACGT
GCGCGAGCAGCTCTCGTCCGAGACGGGCCTGGACATGCGCGTGGTGCAGGTTTGGTTCCAGAACCGCCGGGCCAAGGAGAAGAGGCTGAA
GAAGGACGCCGGCCGGCAGCGCTGGGGGCAGTATTTCCGCAACATGAAGCGCTCCCGCGGCGGCTCCAAGTCGGACAAGGACAGCGTTCA
GGAGGGGCAGGACAGCGACGCTGAGGTCTCCTTCCCCGATGAGCCTTCCTTGGCGGAAATGGGCCCGGCCAATGGCCTCTACGGGAGCTT
GGGGGAACCCACCCAGGCCTTGGGCCGGCCCTCGGGAGCCCTGGGCAACTTCTCCCTGGAGCATGGAGGCCTGGCAGGCCCAGAGCAGTA
CCGAGAGCTGCGTCCCGGCAGCCCCTACGGTGTCCCCCCATCCCCCGCCGCCCCGCAGAGCCTCCCTGGCCCCCAGCCCCTCCTCTCCAG
CCTGGTGTACCCAGACACCAGCTTGGGCCTTGTGCCCTCGGGAGCCCCCGGCGGGCCCCCACCCATGAGGGTGCTGGCAGGGAACGGACC
CAGTTCTGACCTATCCACGGGGAGCAGCGGGGGTTACCCCGACTTCCCTGCCAGCCCCGCCTCCTGGCTGGATGAGGTAGACCACGCTCA
GTTCTGACCCAGGCCCGGCTCCACCCTGCACCTCACACGAGGGAGCTGCCCCTGGGTGGGCGGCTCGGGGCTGCTGGGGTTTCCGAGGAA
GTGGGGCCAGGGCGTCAAGGGAGGGCTGGTGCCTTCGGAGCCTCCCACTGCCGACCGCACAGCTCCCTCTCTGGGGGCTGAGGGACCCAC
CTGGCCCCTCCTCTGACACAGGGCTGGCCCGCCAGGTGGCCTCCCAGCAAGCCAGCCTTTTTTGTAAGCAAATTTCTCCCCTTTATTGAC
CAATTAACTGAGCACTTGCTGCTATTTCTAGACATGAAATGTCACCTTGCTGAGGCCCAGCCCAGCCCAGCATAGCCCGAGGGCTGGAAA
AACGCTTTCATCTCTAAAACTGAGAAATCATCATAATTGTGCTTTCACTTCCCAGGCTCCATGTGTCTTGGAGCCGTCACCCCGAGGCTC
CCTCTTTAGGTCGGAGATTGGCCTTGCCTGTCGAGGCAAGAGGCTGCAGAGGCGGGGACACACCTGTGTCCTCCGGGAGAGGCCCCCTCC
TCTCCCCAGACCACAGGGGGCCTCTCTGCCTCCAGCCCCACCTTCCCCGGGAGAAGCTTTCCCCAATCCCCAGGTCTCTAGATCATTCTG
TTCTCGAGTATCCTGTGGAGGAGGCAAAAATGCCTGGCGCCCCTTCTCTCCAAGCTCAATTCTCTAAGCCCCTCAGGGTCTCCTCCTCAC
CCCACCCCAGGCCCTTGGTGTCCAGGCTGCACCCACAGATGTCTGTTGCCAAACAGCCTGCCCTCCCTGCCGGAGCCGGCTCTGCCAGCC
CCAGATTGGGAAGTCTCCCCGCTGGAGAAGGGTGGGGCTCCTCTGAGCCTGCCCTGCCTCCTCCATCAGATCCTTTGGGAAGAAGTTTCT
GGGAGATGCCCGCAGCTGTGCGTGCCCCAGACACAAAGGCTGGCCTGTGTGTAAGTCAAAGTCACTCCCGCAAACCTGAATCTCGAGCTA
CCTATTGGTTCTGTGAATGTTCTGTGTCTTTTATTTATTCTCGGGTGATCAGCTCTTTCCAAGACTTCAATAAATTTGTCAGTTACAGTC

>80010_80010_6_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000371706_LHX3_chr9_139092599_ENST00000371748_length(amino acids)=1460AA_BP=0
MPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPL
VAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSG
CAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGV
PDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSAR
PQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADR
ANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKC
ESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQAS
SGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSL
PSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQE
DTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMF
SELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDA
YQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYAS
YYSSQYDYGEIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQ
DFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLD
MRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPS
GALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGG

--------------------------------------------------------------
>80010_80010_7_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000431893_LHX3_chr9_139092599_ENST00000371746_length(transcript)=5458nt_BP=3268nt
ATGCCTGGGCTCGACCGACCCCTGAGCAGGCAAAACCCACATGACGGTGTGGTCACCCCAGCAGCATCCCCTTCCCTCCCTCAGCCTGGT
CTGCAGATGCCAGGACAGTGGGGGCCAGTGCAGGGAGGCCCACAGCCCTCGGGGCAACATCGTTCACCCTGCCCTGAAGGACCTGTTCCC
AGCGGGGTGCCCTGTGCCACCAGCGTTCCTCATTTCCCCACCCCGTCCATCCTACATCAGGGCCCTGGTCATGAGCAACACAGCCCTCTG
GTGGCTCCCCCAGCAGCCTTGCCCAGTGACGGAAGAGACGAGGTGAGCCACTTGCAAAGTGGAAGCCACCTGGCCAATAACTCTGATCCT
GAAAGTACATTCAGGCAAAATCCCAGAATTGTGAATCACTGGGCAAGCCCAGAGCTCAGGCAGAATCCAGGAGTGAAGAATGAGCACCGG
CCCGCCTCTGCTCTTGTGAACCCCCTCGCCCGGGGAGATAGCCCAGAAAACCGTACGCACCACCCACTGGGGGCTGGGGCCGGGTCTGGC
TGTGCCCCGCTAGAAGCAGACTCAGGAGCTTCAGGAGCTCTGGCGATGTTTTTCCAAGGGGGAGAGACAGAAAATGAGGAGAATCTCTCA
TCTGAAAAAGCAGGCTTATCTGGTCAAGCGGACTTTGACGATTTCTGCTCCAGCCCTGGGCTAGGCCGTCCGCCCGCACCTACACACGTG
GGGGCAGGCAGCCTCTGCCAGGCCCTTCTCCCAGGCCCCAGCAATGAGGCTGCTGGTGATGTGTGGGGTGACACAGCGAGCACAGGGGTG
CCGGATGCCAGCGGCTCGCAGTATGAGAATGTTGAGAACTTAGAATTTGTTCAGAATCAAGAAGTTCTGCCAAGTGAGCCCCTCAATTTG
GACCCTTCCTCCCCGAGTGACCAGTTCAGATATGGGCCCCTTCCTGGGCCAGCTGTGCCCAGGCATGGTGCTGTGTGCCACACCGGAGCC
CCTGATGCCACACTGCATACAGTGCACCCTGACAGCGTGTCATCCAGCTATAGCAGCAGAAGCCACGGAAGGCTCTCAGGCTCAGCCAGG
CCCCAGGAGCTGGTTGGCACATTCATTCAGCAAGAAGTTGGAAAACCCGAGGATGAAGCTTCAGGTAGTTTTTTTAAGCAAATCGATTCT
TCTCCCGTAGGAGGTGAAACAGACGAGACCACTGTGAGCCAGAATTACCGTGGCAGCGTGTCCCAGCCCTCAACCCCGAGCCCCCCGAAA
CCTACAGGAATATTTCAGACAAGTGCAAATAGTTCTTTCGAACCGGTAAAATCTCACTTAGTTGGGGTAAAACCATTTGAGGCAGATCGC
GCCAACGTGGTTGGTGAAGTAAGGGAGACCTGTGTCCGCCAGAAGCAGTGCAGACCAGCTGCCGCCCTGCCCGATGCTTCCCCTGGCAAC
CTGGAGCAGCCACCAGACAACATGGAGACCCTCTGTGCACCCCAGGTCTGTCCCCTGCCTCTTAACTCCACCACGGAAGCTGTGCACATG
CTTCCGCACGCAGGGGCACCGCCCTTGGATACTGTGTATCCAGCACCCGAGAAGAGGCCTTCAGCCAGGACCCAGGGGCCCGTGAAGTGT
GAGAGCCCAGCAACGACTCTGTGGGCGCAAAGTGAGCTGCCAGATTTTGGAGGCAACGTCCTTCTGGCCCCTGCAGCCCCGGCGCTTTAT
GTGTGTGCAAAACCTCAGCCACCTGTTGTTCAGCCTCCAGAAGAGGCGATGTCCGGGCAGCAGTCACGGAACCCAAGCTCGGCGGCCCCG
GTGCAGAGCCGAGGTGGCATTGGTGCTTCTGAGAACCTTGAGAATCCTCCCAAAATGGGAGAGGAGGAGGCCCTTCAGTCCCAGGCGAGT
TCTGGTTATGCAAGTTTATTATCCTCACCGCCCACTGAGTCTCTGCAGAATCCTCCAGTCTTGATTGCTCAGCCTGATCACAGCTATAAT
CTGGCTCAGCCCATTAACTTTTCTGTGTCCTTATCGAACTCTCATGAGAAGAATCAGTCCTGGAGAGAGGCTTTGGTGGGGGATAGACCT
GCAGTCAGCAGTTGGGCTCTCGGTGGTGATTCTGGGGAGAACACTTCTTTGTCTGGGATTCCAACCAGCTCTGTCCTTAGCTTGTCTCTG
CCTAGCAGTGTTGCCCAAAGTAATTTTCCACAAGGTTCTGGTGCTTCCGAAATGGTTTCTAATCAGCCTGCTAATTTGCTGGTTCAACCA
CCATCCCAGCCAGTTCCAGAGAACTTGGTTCCAGAAAGTCAAAAGGATCGTAAGGCAGGAAGTGCTCTTCCCGGATTTGCTAATAGCCCT
GCTGGAAGCACAAGTGTGGTGTTAGTTCCACCTGCACACGGCACCCTGGTGCCTGATGGTAATAAGGCAAACCATTCCAGTCATCAGGAA
GACACTTACGGAGCCCTAGACTTTACCTTAAGCAGGACTTTGGAAAATCCTGTAAACGTGTACAACCCGTCCCATTCTGACAGCCTCGCT
TCTCAGCAAAGTGTTGCCAGTCATCCCAGACAATCTGGGCCTGGGGCGCCTAACCTTGACCGTTTTTATCAGCAGGTCACGAAAGATGCC
CAGGGCCAGCCTGGCCTCGAAAGAGCCCAGCAGGAGCTGGTGCCACCCCAGCAACAGGCTTCTCCCCCACAACTACCCAAAGCCATGTTT
TCGGAGCTGTCAAATCCAGAAAGTCTGCCCGCACAGGGACAGGCCCAGAACTCAGCACAGTCACCAGCAAGTCTGGTTCTGGTCGACGCG
GGTCAGCAGCTGCCCCCTCGGCCTCCTCAGTCCTCTAGCGTGTCTCTGGTGTCCAGTGGCTCCGGCCAGGCAGCTGTGCCGTCAGAGCAG
CCGTGGCCACAGCCAGTGCCTGCACTTGCCCCCGGCCCACCGCCTCAGGACCTGGCCGCCTACTACTACTACCGGCCTTTGTACGATGCC
TACCAGCCTCAGTACTCTTTGCCGTACCCACCGGAGCCTGGCGCAGCCTCCCTCTATTACCAGGATGTCTACAGCCTCTATGAGCCTCGA
TACAGGCCCTATGATGGTGCTGCGTCTGCTTACGCCCAGAACTACCGCTATCCCGAGCCCGAGCGGCCCAGCTCCCGAGCCAGCCACTCC
TCGGAACGGCCACCTCCCAGGCAAGGATATCCTGAAGGATACTATAGTTCCAAAAGTGGATGGAGCAGTCAGAGCGATTACTATGCAAGC
TATTACTCCAGCCAGTACGATTATGGAGAGATCCCGCTGTGCGCTGGCTGTGACCAGCACATCCTGGACCGCTTCATCCTCAAGGCTCTG
GACCGCCACTGGCACAGCAAGTGTCTCAAGTGCAGCGACTGCCACACGCCACTGGCCGAGCGCTGCTTCAGCCGAGGGGAGAGCGTTTAC
TGCAAGGACGACTTTTTCAAGCGCTTCGGGACCAAGTGCGCCGCGTGCCAGCTGGGCATCCCGCCCACGCAGGTGGTGCGCCGCGCCCAG
GACTTCGTGTACCACCTGCACTGCTTTGCCTGCGTCGTGTGCAAGCGGCAGCTGGCCACGGGCGACGAGTTCTACCTCATGGAGGACAGC
CGGCTCGTGTGCAAGGCGGACTACGAAACCGCCAAGCAGCGAGAGGCCGAGGCCACGGCCAAGCGGCCGCGCACGACCATCACCGCCAAG
CAGCTGGAGACGCTGAAGAGCGCTTACAACACCTCGCCCAAGCCGGCGCGCCACGTGCGCGAGCAGCTCTCGTCCGAGACGGGCCTGGAC
ATGCGCGTGGTGCAGGTTTGGTTCCAGAACCGCCGGGCCAAGGAGAAGAGGCTGAAGAAGGACGCCGGCCGGCAGCGCTGGGGGCAGTAT
TTCCGCAACATGAAGCGCTCCCGCGGCGGCTCCAAGTCGGACAAGGACAGCGTTCAGGAGGGGCAGGACAGCGACGCTGAGGTCTCCTTC
CCCGATGAGCCTTCCTTGGCGGAAATGGGCCCGGCCAATGGCCTCTACGGGAGCTTGGGGGAACCCACCCAGGCCTTGGGCCGGCCCTCG
GGAGCCCTGGGCAACTTCTCCCTGGAGCATGGAGGCCTGGCAGGCCCAGAGCAGTACCGAGAGCTGCGTCCCGGCAGCCCCTACGGTGTC
CCCCCATCCCCCGCCGCCCCGCAGAGCCTCCCTGGCCCCCAGCCCCTCCTCTCCAGCCTGGTGTACCCAGACACCAGCTTGGGCCTTGTG
CCCTCGGGAGCCCCCGGCGGGCCCCCACCCATGAGGGTGCTGGCAGGGAACGGACCCAGTTCTGACCTATCCACGGGGAGCAGCGGGGGT
TACCCCGACTTCCCTGCCAGCCCCGCCTCCTGGCTGGATGAGGTAGACCACGCTCAGTTCTGACCCAGGCCCGGCTCCACCCTGCACCTC
ACACGAGGGAGCTGCCCCTGGGTGGGCGGCTCGGGGCTGCTGGGGTTTCCGAGGAAGTGGGGCCAGGGCGTCAAGGGAGGGCTGGTGCCT
TCGGAGCCTCCCACTGCCGACCGCACAGCTCCCTCTCTGGGGGCTGAGGGACCCACCTGGCCCCTCCTCTGACACAGGGCTGGCCCGCCA
GGTGGCCTCCCAGCAAGCCAGCCTTTTTTGTAAGCAAATTTCTCCCCTTTATTGACCAATTAACTGAGCACTTGCTGCTATTTCTAGACA
TGAAATGTCACCTTGCTGAGGCCCAGCCCAGCCCAGCATAGCCCGAGGGCTGGAAAAACGCTTTCATCTCTAAAACTGAGAAATCATCAT
AATTGTGCTTTCACTTCCCAGGCTCCATGTGTCTTGGAGCCGTCACCCCGAGGCTCCCTCTTTAGGTCGGAGATTGGCCTTGCCTGTCGA
GGCAAGAGGCTGCAGAGGCGGGGACACACCTGTGTCCTCCGGGAGAGGCCCCCTCCTCTCCCCAGACCACAGGGGGCCTCTCTGCCTCCA
GCCCCACCTTCCCCGGGAGAAGCTTTCCCCAATCCCCAGGTCTCTAGATCATTCTGTTCTCGAGTATCCTGTGGAGGAGGCAAAAATGCC
TGGCGCCCCTTCTCTCCAAGCTCAATTCTCTAAGCCCCTCAGGGTCTCCTCCTCACCCCACCCCAGGCCCTTGGTGTCCAGGCTGCACCC
ACAGATGTCTGTTGCCAAACAGCCTGCCCTCCCTGCCGGAGCCGGCTCTGCCAGCCCCAGATTGGGAAGTCTCCCCGCTGGAGAAGGGTG
GGGCTCCTCTGAGCCTGCCCTGCCTCCTCCATCAGATCCTTTGGGAAGAAGTTTCTGGGAGATGCCCGCAGCTGTGCGTGCCCCAGACAC
AAAGGCTGGCCTGTGTGTAAGTCAAAGTCACTCCCGCAAACCTGAATCTCGAGCTACCTATTGGTTCTGTGAATGTTCTGTGTCTTTTAT

>80010_80010_7_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000431893_LHX3_chr9_139092599_ENST00000371746_length(amino acids)=1460AA_BP=0
MPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPL
VAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSG
CAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGV
PDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSAR
PQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADR
ANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKC
ESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQAS
SGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSL
PSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQE
DTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMF
SELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDA
YQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYAS
YYSSQYDYGEIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQ
DFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLD
MRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPS
GALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGG

--------------------------------------------------------------
>80010_80010_8_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000431893_LHX3_chr9_139092599_ENST00000371748_length(transcript)=5457nt_BP=3268nt
ATGCCTGGGCTCGACCGACCCCTGAGCAGGCAAAACCCACATGACGGTGTGGTCACCCCAGCAGCATCCCCTTCCCTCCCTCAGCCTGGT
CTGCAGATGCCAGGACAGTGGGGGCCAGTGCAGGGAGGCCCACAGCCCTCGGGGCAACATCGTTCACCCTGCCCTGAAGGACCTGTTCCC
AGCGGGGTGCCCTGTGCCACCAGCGTTCCTCATTTCCCCACCCCGTCCATCCTACATCAGGGCCCTGGTCATGAGCAACACAGCCCTCTG
GTGGCTCCCCCAGCAGCCTTGCCCAGTGACGGAAGAGACGAGGTGAGCCACTTGCAAAGTGGAAGCCACCTGGCCAATAACTCTGATCCT
GAAAGTACATTCAGGCAAAATCCCAGAATTGTGAATCACTGGGCAAGCCCAGAGCTCAGGCAGAATCCAGGAGTGAAGAATGAGCACCGG
CCCGCCTCTGCTCTTGTGAACCCCCTCGCCCGGGGAGATAGCCCAGAAAACCGTACGCACCACCCACTGGGGGCTGGGGCCGGGTCTGGC
TGTGCCCCGCTAGAAGCAGACTCAGGAGCTTCAGGAGCTCTGGCGATGTTTTTCCAAGGGGGAGAGACAGAAAATGAGGAGAATCTCTCA
TCTGAAAAAGCAGGCTTATCTGGTCAAGCGGACTTTGACGATTTCTGCTCCAGCCCTGGGCTAGGCCGTCCGCCCGCACCTACACACGTG
GGGGCAGGCAGCCTCTGCCAGGCCCTTCTCCCAGGCCCCAGCAATGAGGCTGCTGGTGATGTGTGGGGTGACACAGCGAGCACAGGGGTG
CCGGATGCCAGCGGCTCGCAGTATGAGAATGTTGAGAACTTAGAATTTGTTCAGAATCAAGAAGTTCTGCCAAGTGAGCCCCTCAATTTG
GACCCTTCCTCCCCGAGTGACCAGTTCAGATATGGGCCCCTTCCTGGGCCAGCTGTGCCCAGGCATGGTGCTGTGTGCCACACCGGAGCC
CCTGATGCCACACTGCATACAGTGCACCCTGACAGCGTGTCATCCAGCTATAGCAGCAGAAGCCACGGAAGGCTCTCAGGCTCAGCCAGG
CCCCAGGAGCTGGTTGGCACATTCATTCAGCAAGAAGTTGGAAAACCCGAGGATGAAGCTTCAGGTAGTTTTTTTAAGCAAATCGATTCT
TCTCCCGTAGGAGGTGAAACAGACGAGACCACTGTGAGCCAGAATTACCGTGGCAGCGTGTCCCAGCCCTCAACCCCGAGCCCCCCGAAA
CCTACAGGAATATTTCAGACAAGTGCAAATAGTTCTTTCGAACCGGTAAAATCTCACTTAGTTGGGGTAAAACCATTTGAGGCAGATCGC
GCCAACGTGGTTGGTGAAGTAAGGGAGACCTGTGTCCGCCAGAAGCAGTGCAGACCAGCTGCCGCCCTGCCCGATGCTTCCCCTGGCAAC
CTGGAGCAGCCACCAGACAACATGGAGACCCTCTGTGCACCCCAGGTCTGTCCCCTGCCTCTTAACTCCACCACGGAAGCTGTGCACATG
CTTCCGCACGCAGGGGCACCGCCCTTGGATACTGTGTATCCAGCACCCGAGAAGAGGCCTTCAGCCAGGACCCAGGGGCCCGTGAAGTGT
GAGAGCCCAGCAACGACTCTGTGGGCGCAAAGTGAGCTGCCAGATTTTGGAGGCAACGTCCTTCTGGCCCCTGCAGCCCCGGCGCTTTAT
GTGTGTGCAAAACCTCAGCCACCTGTTGTTCAGCCTCCAGAAGAGGCGATGTCCGGGCAGCAGTCACGGAACCCAAGCTCGGCGGCCCCG
GTGCAGAGCCGAGGTGGCATTGGTGCTTCTGAGAACCTTGAGAATCCTCCCAAAATGGGAGAGGAGGAGGCCCTTCAGTCCCAGGCGAGT
TCTGGTTATGCAAGTTTATTATCCTCACCGCCCACTGAGTCTCTGCAGAATCCTCCAGTCTTGATTGCTCAGCCTGATCACAGCTATAAT
CTGGCTCAGCCCATTAACTTTTCTGTGTCCTTATCGAACTCTCATGAGAAGAATCAGTCCTGGAGAGAGGCTTTGGTGGGGGATAGACCT
GCAGTCAGCAGTTGGGCTCTCGGTGGTGATTCTGGGGAGAACACTTCTTTGTCTGGGATTCCAACCAGCTCTGTCCTTAGCTTGTCTCTG
CCTAGCAGTGTTGCCCAAAGTAATTTTCCACAAGGTTCTGGTGCTTCCGAAATGGTTTCTAATCAGCCTGCTAATTTGCTGGTTCAACCA
CCATCCCAGCCAGTTCCAGAGAACTTGGTTCCAGAAAGTCAAAAGGATCGTAAGGCAGGAAGTGCTCTTCCCGGATTTGCTAATAGCCCT
GCTGGAAGCACAAGTGTGGTGTTAGTTCCACCTGCACACGGCACCCTGGTGCCTGATGGTAATAAGGCAAACCATTCCAGTCATCAGGAA
GACACTTACGGAGCCCTAGACTTTACCTTAAGCAGGACTTTGGAAAATCCTGTAAACGTGTACAACCCGTCCCATTCTGACAGCCTCGCT
TCTCAGCAAAGTGTTGCCAGTCATCCCAGACAATCTGGGCCTGGGGCGCCTAACCTTGACCGTTTTTATCAGCAGGTCACGAAAGATGCC
CAGGGCCAGCCTGGCCTCGAAAGAGCCCAGCAGGAGCTGGTGCCACCCCAGCAACAGGCTTCTCCCCCACAACTACCCAAAGCCATGTTT
TCGGAGCTGTCAAATCCAGAAAGTCTGCCCGCACAGGGACAGGCCCAGAACTCAGCACAGTCACCAGCAAGTCTGGTTCTGGTCGACGCG
GGTCAGCAGCTGCCCCCTCGGCCTCCTCAGTCCTCTAGCGTGTCTCTGGTGTCCAGTGGCTCCGGCCAGGCAGCTGTGCCGTCAGAGCAG
CCGTGGCCACAGCCAGTGCCTGCACTTGCCCCCGGCCCACCGCCTCAGGACCTGGCCGCCTACTACTACTACCGGCCTTTGTACGATGCC
TACCAGCCTCAGTACTCTTTGCCGTACCCACCGGAGCCTGGCGCAGCCTCCCTCTATTACCAGGATGTCTACAGCCTCTATGAGCCTCGA
TACAGGCCCTATGATGGTGCTGCGTCTGCTTACGCCCAGAACTACCGCTATCCCGAGCCCGAGCGGCCCAGCTCCCGAGCCAGCCACTCC
TCGGAACGGCCACCTCCCAGGCAAGGATATCCTGAAGGATACTATAGTTCCAAAAGTGGATGGAGCAGTCAGAGCGATTACTATGCAAGC
TATTACTCCAGCCAGTACGATTATGGAGAGATCCCGCTGTGCGCTGGCTGTGACCAGCACATCCTGGACCGCTTCATCCTCAAGGCTCTG
GACCGCCACTGGCACAGCAAGTGTCTCAAGTGCAGCGACTGCCACACGCCACTGGCCGAGCGCTGCTTCAGCCGAGGGGAGAGCGTTTAC
TGCAAGGACGACTTTTTCAAGCGCTTCGGGACCAAGTGCGCCGCGTGCCAGCTGGGCATCCCGCCCACGCAGGTGGTGCGCCGCGCCCAG
GACTTCGTGTACCACCTGCACTGCTTTGCCTGCGTCGTGTGCAAGCGGCAGCTGGCCACGGGCGACGAGTTCTACCTCATGGAGGACAGC
CGGCTCGTGTGCAAGGCGGACTACGAAACCGCCAAGCAGCGAGAGGCCGAGGCCACGGCCAAGCGGCCGCGCACGACCATCACCGCCAAG
CAGCTGGAGACGCTGAAGAGCGCTTACAACACCTCGCCCAAGCCGGCGCGCCACGTGCGCGAGCAGCTCTCGTCCGAGACGGGCCTGGAC
ATGCGCGTGGTGCAGGTTTGGTTCCAGAACCGCCGGGCCAAGGAGAAGAGGCTGAAGAAGGACGCCGGCCGGCAGCGCTGGGGGCAGTAT
TTCCGCAACATGAAGCGCTCCCGCGGCGGCTCCAAGTCGGACAAGGACAGCGTTCAGGAGGGGCAGGACAGCGACGCTGAGGTCTCCTTC
CCCGATGAGCCTTCCTTGGCGGAAATGGGCCCGGCCAATGGCCTCTACGGGAGCTTGGGGGAACCCACCCAGGCCTTGGGCCGGCCCTCG
GGAGCCCTGGGCAACTTCTCCCTGGAGCATGGAGGCCTGGCAGGCCCAGAGCAGTACCGAGAGCTGCGTCCCGGCAGCCCCTACGGTGTC
CCCCCATCCCCCGCCGCCCCGCAGAGCCTCCCTGGCCCCCAGCCCCTCCTCTCCAGCCTGGTGTACCCAGACACCAGCTTGGGCCTTGTG
CCCTCGGGAGCCCCCGGCGGGCCCCCACCCATGAGGGTGCTGGCAGGGAACGGACCCAGTTCTGACCTATCCACGGGGAGCAGCGGGGGT
TACCCCGACTTCCCTGCCAGCCCCGCCTCCTGGCTGGATGAGGTAGACCACGCTCAGTTCTGACCCAGGCCCGGCTCCACCCTGCACCTC
ACACGAGGGAGCTGCCCCTGGGTGGGCGGCTCGGGGCTGCTGGGGTTTCCGAGGAAGTGGGGCCAGGGCGTCAAGGGAGGGCTGGTGCCT
TCGGAGCCTCCCACTGCCGACCGCACAGCTCCCTCTCTGGGGGCTGAGGGACCCACCTGGCCCCTCCTCTGACACAGGGCTGGCCCGCCA
GGTGGCCTCCCAGCAAGCCAGCCTTTTTTGTAAGCAAATTTCTCCCCTTTATTGACCAATTAACTGAGCACTTGCTGCTATTTCTAGACA
TGAAATGTCACCTTGCTGAGGCCCAGCCCAGCCCAGCATAGCCCGAGGGCTGGAAAAACGCTTTCATCTCTAAAACTGAGAAATCATCAT
AATTGTGCTTTCACTTCCCAGGCTCCATGTGTCTTGGAGCCGTCACCCCGAGGCTCCCTCTTTAGGTCGGAGATTGGCCTTGCCTGTCGA
GGCAAGAGGCTGCAGAGGCGGGGACACACCTGTGTCCTCCGGGAGAGGCCCCCTCCTCTCCCCAGACCACAGGGGGCCTCTCTGCCTCCA
GCCCCACCTTCCCCGGGAGAAGCTTTCCCCAATCCCCAGGTCTCTAGATCATTCTGTTCTCGAGTATCCTGTGGAGGAGGCAAAAATGCC
TGGCGCCCCTTCTCTCCAAGCTCAATTCTCTAAGCCCCTCAGGGTCTCCTCCTCACCCCACCCCAGGCCCTTGGTGTCCAGGCTGCACCC
ACAGATGTCTGTTGCCAAACAGCCTGCCCTCCCTGCCGGAGCCGGCTCTGCCAGCCCCAGATTGGGAAGTCTCCCCGCTGGAGAAGGGTG
GGGCTCCTCTGAGCCTGCCCTGCCTCCTCCATCAGATCCTTTGGGAAGAAGTTTCTGGGAGATGCCCGCAGCTGTGCGTGCCCCAGACAC
AAAGGCTGGCCTGTGTGTAAGTCAAAGTCACTCCCGCAAACCTGAATCTCGAGCTACCTATTGGTTCTGTGAATGTTCTGTGTCTTTTAT

>80010_80010_8_SEC16A-LHX3_SEC16A_chr9_139362867_ENST00000431893_LHX3_chr9_139092599_ENST00000371748_length(amino acids)=1460AA_BP=0
MPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPL
VAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSG
CAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGV
PDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSAR
PQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADR
ANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKC
ESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQAS
SGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSL
PSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQE
DTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMF
SELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDA
YQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYAS
YYSSQYDYGEIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQ
DFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLD
MRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPS
GALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGG

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Fusion Gene PPI Analysis for SEC16A-LHX3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSEC16Achr9:139362867chr9:139092599ENST00000290037-3291101_14001089.33333333333332160.0MIA3
HgeneSEC16Achr9:139362867chr9:139092599ENST00000371706-3281101_14001089.33333333333332135.0MIA3
HgeneSEC16Achr9:139362867chr9:139092599ENST00000431893-3291101_14001089.33333333333332155.0MIA3


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SEC16A-LHX3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SEC16A-LHX3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource