FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:SEC22A-PHEX (FusionGDB2 ID:80025)

Fusion Gene Summary for SEC22A-PHEX

check button Fusion gene summary
Fusion gene informationFusion gene name: SEC22A-PHEX
Fusion gene ID: 80025
HgeneTgene
Gene symbol

SEC22A

PHEX

Gene ID

26984

5251

Gene nameSEC22 homolog A, vesicle trafficking proteinphosphate regulating endopeptidase homolog X-linked
SynonymsSEC22L2HPDR|HPDR1|HYP|HYP1|LXHR|PEX|XLH
Cytomap

3q21.1

Xp22.11

Type of geneprotein-codingprotein-coding
Descriptionvesicle-trafficking protein SEC22aSEC22 vesicle trafficking protein homolog ASEC22 vesicle trafficking protein-like 2phosphate-regulating neutral endopeptidase PHEXX-linked hypophosphatemia proteinmetalloendopeptidase homolog PEXphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)phosphate-re
Modification date2020031320200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000309934, ENST00000481965, 
ENST00000492595, ENST00000477063, 
ENST00000475778, ENST00000379374, 
ENST00000418858, ENST00000535894, 
ENST00000537599, 
Fusion gene scores* DoF score4 X 3 X 3=365 X 5 X 5=125
# samples 46
** MAII scorelog2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(6/125*10)=-1.05889368905357
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SEC22A [Title/Abstract] AND PHEX [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSEC22A(122978436)-PHEX(22186429), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePHEX

GO:0006508

proteolysis

11409890


check buttonFusion gene breakpoints across SEC22A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PHEX (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4IY-01ASEC22Achr3

122978436

+PHEXchrX

22186429

+


Top

Fusion Gene ORF analysis for SEC22A-PHEX

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000309934ENST00000475778SEC22Achr3

122978436

+PHEXchrX

22186429

+
5CDS-intronENST00000481965ENST00000475778SEC22Achr3

122978436

+PHEXchrX

22186429

+
5CDS-intronENST00000492595ENST00000475778SEC22Achr3

122978436

+PHEXchrX

22186429

+
Frame-shiftENST00000481965ENST00000379374SEC22Achr3

122978436

+PHEXchrX

22186429

+
Frame-shiftENST00000481965ENST00000418858SEC22Achr3

122978436

+PHEXchrX

22186429

+
Frame-shiftENST00000481965ENST00000535894SEC22Achr3

122978436

+PHEXchrX

22186429

+
Frame-shiftENST00000481965ENST00000537599SEC22Achr3

122978436

+PHEXchrX

22186429

+
In-frameENST00000309934ENST00000379374SEC22Achr3

122978436

+PHEXchrX

22186429

+
In-frameENST00000309934ENST00000418858SEC22Achr3

122978436

+PHEXchrX

22186429

+
In-frameENST00000309934ENST00000535894SEC22Achr3

122978436

+PHEXchrX

22186429

+
In-frameENST00000309934ENST00000537599SEC22Achr3

122978436

+PHEXchrX

22186429

+
In-frameENST00000492595ENST00000379374SEC22Achr3

122978436

+PHEXchrX

22186429

+
In-frameENST00000492595ENST00000418858SEC22Achr3

122978436

+PHEXchrX

22186429

+
In-frameENST00000492595ENST00000535894SEC22Achr3

122978436

+PHEXchrX

22186429

+
In-frameENST00000492595ENST00000537599SEC22Achr3

122978436

+PHEXchrX

22186429

+
intron-3CDSENST00000477063ENST00000379374SEC22Achr3

122978436

+PHEXchrX

22186429

+
intron-3CDSENST00000477063ENST00000418858SEC22Achr3

122978436

+PHEXchrX

22186429

+
intron-3CDSENST00000477063ENST00000535894SEC22Achr3

122978436

+PHEXchrX

22186429

+
intron-3CDSENST00000477063ENST00000537599SEC22Achr3

122978436

+PHEXchrX

22186429

+
intron-intronENST00000477063ENST00000475778SEC22Achr3

122978436

+PHEXchrX

22186429

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000492595SEC22Achr3122978436+ENST00000379374PHEXchrX22186429+4974771361616526
ENST00000492595SEC22Achr3122978436+ENST00000537599PHEXchrX22186429+1770771361454472
ENST00000492595SEC22Achr3122978436+ENST00000535894PHEXchrX22186429+1960771361616526
ENST00000492595SEC22Achr3122978436+ENST00000418858PHEXchrX22186429+1756771361616526
ENST00000309934SEC22Achr3122978436+ENST00000379374PHEXchrX22186429+582216198842464526
ENST00000309934SEC22Achr3122978436+ENST00000537599PHEXchrX22186429+261816198842302472
ENST00000309934SEC22Achr3122978436+ENST00000535894PHEXchrX22186429+280816198842464526
ENST00000309934SEC22Achr3122978436+ENST00000418858PHEXchrX22186429+260416198842464526

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000492595ENST00000379374SEC22Achr3122978436+PHEXchrX22186429+0.0001474730.99985254
ENST00000492595ENST00000537599SEC22Achr3122978436+PHEXchrX22186429+0.0005086790.99949133
ENST00000492595ENST00000535894SEC22Achr3122978436+PHEXchrX22186429+0.0004764660.9995235
ENST00000492595ENST00000418858SEC22Achr3122978436+PHEXchrX22186429+0.0005972740.99940276
ENST00000309934ENST00000379374SEC22Achr3122978436+PHEXchrX22186429+0.000140660.99985933
ENST00000309934ENST00000537599SEC22Achr3122978436+PHEXchrX22186429+0.0002968230.9997031
ENST00000309934ENST00000535894SEC22Achr3122978436+PHEXchrX22186429+0.0003048670.9996952
ENST00000309934ENST00000418858SEC22Achr3122978436+PHEXchrX22186429+0.0003559240.99964404

Top

Fusion Genomic Features for SEC22A-PHEX


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SEC22Achr3122978436+PHEXchrX22186428+6.33E-070.9999994
SEC22Achr3122978436+PHEXchrX22186428+6.33E-070.9999994

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for SEC22A-PHEX


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:122978436/chrX:22186429)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSEC22Achr3:122978436chrX:22186429ENST00000309934+568_119241308.0DomainLongin
HgeneSEC22Achr3:122978436chrX:22186429ENST00000492595+678_119241308.0DomainLongin
HgeneSEC22Achr3:122978436chrX:22186429ENST00000309934+56209_226241308.0Topological domainLumenal
HgeneSEC22Achr3:122978436chrX:22186429ENST00000309934+562_187241308.0Topological domainCytoplasmic
HgeneSEC22Achr3:122978436chrX:22186429ENST00000492595+67209_226241308.0Topological domainLumenal
HgeneSEC22Achr3:122978436chrX:22186429ENST00000492595+672_187241308.0Topological domainCytoplasmic
HgeneSEC22Achr3:122978436chrX:22186429ENST00000309934+56188_208241308.0TransmembraneHelical
HgeneSEC22Achr3:122978436chrX:22186429ENST00000492595+67188_208241308.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSEC22Achr3:122978436chrX:22186429ENST00000309934+56248_253241308.0Topological domainCytoplasmic
HgeneSEC22Achr3:122978436chrX:22186429ENST00000309934+56272_274241308.0Topological domainLumenal
HgeneSEC22Achr3:122978436chrX:22186429ENST00000309934+56296_307241308.0Topological domainCytoplasmic
HgeneSEC22Achr3:122978436chrX:22186429ENST00000492595+67248_253241308.0Topological domainCytoplasmic
HgeneSEC22Achr3:122978436chrX:22186429ENST00000492595+67272_274241308.0Topological domainLumenal
HgeneSEC22Achr3:122978436chrX:22186429ENST00000492595+67296_307241308.0Topological domainCytoplasmic
HgeneSEC22Achr3:122978436chrX:22186429ENST00000309934+56227_247241308.0TransmembraneHelical
HgeneSEC22Achr3:122978436chrX:22186429ENST00000309934+56254_271241308.0TransmembraneHelical
HgeneSEC22Achr3:122978436chrX:22186429ENST00000309934+56275_295241308.0TransmembraneHelical
HgeneSEC22Achr3:122978436chrX:22186429ENST00000492595+67227_247241308.0TransmembraneHelical
HgeneSEC22Achr3:122978436chrX:22186429ENST00000492595+67254_271241308.0TransmembraneHelical
HgeneSEC22Achr3:122978436chrX:22186429ENST00000492595+67275_295241308.0TransmembraneHelical
TgenePHEXchr3:122978436chrX:22186429ENST00000379374112253_749468750.0DomainPeptidase M13
TgenePHEXchr3:122978436chrX:22186429ENST0000037937411221_20468750.0Topological domainCytoplasmic
TgenePHEXchr3:122978436chrX:22186429ENST00000379374112242_641468750.0Topological domainExtracellular
TgenePHEXchr3:122978436chrX:22186429ENST00000379374112221_41468750.0TransmembraneHelical%3B Signal-anchor for type II membrane protein


Top

Fusion Gene Sequence for SEC22A-PHEX


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80025_80025_1_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000309934_PHEX_chrX_22186429_ENST00000379374_length(transcript)=5822nt_BP=1619nt
CTTTCTGTTTAAAATTTTGCCTGGATTTCTGATTATTTTTCTCAAGACAGGTATATATTTAAATTTATTGAGGTTAAAAGGTATGCCTTC
AGACTCTTGTTGAAATTGCCAAATCATTTTGAGAACTGTTTGTACCAGTTTTTACTTCCATCTGTACTTATGAGAATGCCAGACAGAAGT
ATTATTTTTTAAAAAGCTAATGTGGCTGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTGTGGCAGGCGCCTATAGTCCCAGCCACAT
CCTATGCTGTGGCATGGGAACCCAGGCTGAGGCATGAGAATTGCTTGAACCCTGGATGGGGGATGTTGCAGTCAGCCAAGATGGCGCCAC
TGCACTCCAGCCTGGGTGACAGAGCAAGATGCTGTCTCAAAAAAAAAAACAAAAAACAAAAAACAAAAGCTATATGTTAAGTGAAGCATA
GTATGTTGTTTTAATTAGTTTTTTGTTTTTTTTTTCCTCCTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAGCTCAGTGACGCGATT
TCGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCGGCCTCCTGAGTAGCTGGGATTACAGGTGTGCACCACCAC
GCCTGGCTAATTTTTGTATTTTTAGTAGAGAAGGGGTTTCATCATGTTGGCCAGGCTGGTCTCAAACTCCTGATCTTGTGATCCACCCTC
CTCAGCCACCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACACCTGGCCATTTTAATTACTATTCTTATATTACTAGTAAGTTGAACA
TTTTTACATATGCTTATCAAGTTTGGCTTTAATTTTTATGTAACCCAAATTGTTCATTTTGTTTTAGGTCTTCTCTGTTGGTTGAAATGT
CTATGATTTTATCTGCCTCAGTCATTCGTGTCAGAGATGGACTGCCACTTTCTGCTTCTACTGATTATGAACAAAGCACAGGAATGCAGG
AGTGCAGAAAGTATTTTAAAATGCTTTCGAGGAAACTTGCTCAACTTCCTGATAGATGTACACTGAAAACTGGACATTATAACATTAATT
TTATTAGCTCTCTGGGAGTGAGCTACATGATGTTGTGCACTGAAAATTACCCAAATGTTCTCGCCTTCTCTTTCCTGGATGAGCTTCAGA
AGGAGTTCATTACTACTTATAACATGATGAAGACAAATACTGCTGTCAGACCATACTGTTTCATTGAATTTGATAACTTCATTCAGAGGA
CCAAGCAGCGATATAATAATCCCAGGTCTCTTTCAACAAAGATAAATCTTTCTGACATGCAGACGGAAATCAAGCTGAGGCCTCCTTATC
AAATTTCCATGTGCGAACTGGGGTCAGCCAATGGAGTCACATCAGCATTTTCTGTTGACTGTAAAGGTGCTGGTAAGATTTCTTCTGCTC
ACCAGCGACTGGAACCAGCAACTCTGTCAGGGATTGTAGGATTTATCCTTAGTCTTTTATGTGGAGCTCTGAATTTAATTCGAGGCTTTC
ATGCTATAGAAAGTCTCCTGCAGAGTGATGGTGATGATTTTAATTACATCATTGCATTTTTCCTTGGAACAGCAGCCTGCCTTTACCAGG
CGAGAGCTGTTTTGGCAAAAGTTGGCTATCCAGAGTTTATAATGAATGATACTCATGTTAATGAAGACCTCAAAGCTATCAAGTTTTCAG
AAGCCGACTACTTTGGCAACGTCCTACAAACTCGCAAGTATTTAGCACAGTCTGATTTCTTCTGGCTAAGAAAAGCCGTTCCAAAAACAG
AGTGGTTTACAAATCCGACGACTGTCAATGCCTTCTACAGTGCATCCACCAACCAGATCCGATTTCCAGCAGGAGAGCTCCAGAAGCCTT
TCTTTTGGGGAACAGAATATCCTCGATCTCTGAGTTATGGTGCTATAGGAGTAATTGTCGGACATGAATTTACACATGGATTTGATAATA
ATGGTAGAAAATATGATAAAAATGGAAACCTGGATCCTTGGTGGTCTACTGAATCAGAAGAAAAGTTTAAGGAAAAAACAAAATGCATGA
TTAACCAGTATAGCAACTATTATTGGAAGAAAGCTGGCTTAAATGTCAAGGGGAAGAGGACCCTGGGAGAAAATATTGCTGATAATGGAG
GCCTGCGGGAAGCTTTTAGGGCTTACAGGAAATGGATAAATGACAGAAGGCAGGGACTTGAGGAGCCTCTTCTACCAGGCATCACATTCA
CCAACAACCAGCTCTTCTTCCTGAGTTATGCTCATGTGAGGTGCAATTCCTACAGACCAGAAGCTGCCCGAGAACAAGTCCAAATTGGTG
CTCACAGTCCCCCTCAGTTTAGGGTCAATGGTGCAATTAGTAACTTTGAAGAATTCCAGAAAGCTTTTAACTGTCCACCCAATTCCACGA
TGAACAGAGGCATGGACTCCTGCCGACTCTGGTAGCTGGGACGCTGGTTTATGGCATCCTGAGACAGTTGCACAGTGCCAGCGGAGGCTG
CACTGAGCCTTCATCGCCCATTGCTTTAGGCCTGGAGACTTTCATTTTTAGTGCATTTTCATTATTTGGGTAGGTGACCTGCTTGGATCT
AGACAGCATCTGTTCAAAGTTGTAGGGCTTATAAAGTGGAATATAAGAATGAACTAAGTATGTTTCTTTAGAAAATCAAACCAACAAAAA
TAAATCCCTAGGCTACTTTTGTTAAAATGCTATCTGCTAAATTGTTGCTATTGTCCATTTTAGGGTGTTGGCCACAGTTATGTGGTACAT
AGCATTTCAATCTATAGCTTTGTGGGAAGCCTAAATTGATGTATCCTTTAAAAGTTCAATCTATTAAACTTGTAGCCTCTCAATGATGAA
GACATGTGCATGAATACCTGGGAGGGCTTGCTGCTCTGTGGAATGCAGTGCACGTTTTTATGGACAGTAATTACACAGCATTCCTCAACT
GTAAGGTAGTTAAATTAGAAATATGTTTGATCTCCATTTTACACTTTTTGATGAAGTTCTTGCCTTCAGCTTTGGAGTCTGTTGGAATGA
AACTGTGTCTCACAGCTTGCATCTGATGTAGCAGATTGCCCTGTTCAAGTCAGCATGAACAAAGCTCGCAGAAAGGCTACTAGGTAACGG
ATTTGAGTTTATTCAGTAGAAAAAAAGGGAATGAGGACATATCTTTAGGTCCCAGAAGCAGCAAAACCTCCTAGTTACATAACAGCAGGG
AAACTAGGAGATGAAATCTCCAAAATTTTGTCCAGTCTGTATGAACTGCAGTGATTGTCTGTCTGCTAGACACTTTTTTTTAGCCTAATT
CTTGTTCGTTTCATTACCTTCATATGTGTGCATTGTACTGGTTTTGAAATGAGCAGACATTGAGAAAACAATTTTCTGATTCCCCATTAG
GAACATATGATTTTCATTTCCCTTTAGTGCAAAGGAACAAACATCACATTGAGGAGGGAGAAGTGTACCCTTCTTTTTCAGCTTAATGTT
ACCTCTCTTTAAAAAAAAAACATTTTTGAAAAATTTCTTGACTGATGACATTCTAGAATTTATTGATTCAATTTAAAATTCCCTGCATAG
TCCAAATAAACATAATTTTTACTCTTCAAGTCATCTAAAGAGTTGTGAGAAAGAGCAGTACTATGTGTTTTATCCTTAGAGCATTATCCT
TCTAAGTGAACTCCTTTCTTATTACTGAGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGGATAAAATTGTAATGGCCTTAAAGTT
GTTACCTGGCATTTTTGGTTTCTTAAAATAGGCATCCCCCTACTCCCTTTACATTATTCATTAGACATGAGGTGCTGGGTTAAGTGGGCC
AATAGGAAAATCTCAAAAGCAAAATGACAAATTCAGATTAACCACAGGAAGCCATTGTGTGTCCCTGTGATTTGTGATTCTTTTAAAAAA
AAAAAAAATATATATATATATATATATATATATATATATGTATATCTACCTAAGTGTGTGCCATGTCCTTTTGTAGCCATGGGAACGTTT
GAATGGAGAAAAATGGAGGGGCACCATCATGAGGAAACAATTATACTGCATTAGTCAGAGGAGAGCGATTTTCCCTTTGACTTCTTCCTC
TCTGAATGGATAAACTTGTGAAGGGCAGCTACCTTGTCCTCCTCTTAACCTGGCTTAATGTGACCTTAGTTTGTATTTCCAAAAACAAGC
AGTATTAGGTTGGAATTGTATGTGTCTTTTCTCTGGAGGAAGCATTCTGACTTGGTTTAGACATATAAGATACTCTGTTTTATTCCTGGA
CTTGGGTGTTTAAAATCAGCTGAGGTTTATCATGCTTATATGAATAGTGTTTCCCTTCTAGATTTCCTTTATAAACTCCAAATAAACACA
TTCCTGCAGGTCAGAGAAAGTGTTTGATAAAAGCATAGAATTATGGCTTTGGAAAGACAAACTAAGTCACTTGTTGGTTTAGCAAAACTG
GTTGGTGATTAGTTGGGGCCCTCACAGTTTCTAGATGAGAAGCTTACCTTATCCTGATTAACTTTACTTGCTGTAACTGTTATACCGAAA
ATTGTAGGTAGGATGTCCATTACTCAAACAAAGCAGAACAAAACAACAAACCAAAAGCAGCAATACCAAATCATCACTACTAGCTAGAAC
AATGAGAAGGATTGAATTTCCAAATACATGCTTATGTTTAACTCAACTCTTCCAATTACATTCTCATTGTCCTTTCTCTTGGATACCGAT
TGCTAAGATAAACAGACACTGATTAAGTGGTAGAAAGAGAAAGGTAAAATGCAACTGGAAGGGAAAGAAAAAAGTAGGGAGAAGCTGGCC
TATGGATGTGGCTTTGAAGAGAAGACAGGATTTTGGCATTCCTTGCTAAGCACGTTCAATGGAGGAGAGCCATGAAGTTTTACAAAAATA
ATTATGGTAAATTAAAAGGATATTAGATATTGGATCTCAGACTAGGGCTGCTATAATACAGTTCTCTGATTCGCACACCAGATGTTCTGC
CAGCGAACTGTTGTCTGGGCATTGGAAGGAGTTAGGTTTTTTGTGTTTGTGAAAATCTCCTGGATTAGTAAAAAAATTTTCTAGATATAA
AGTGGTTTTATTTGGGCTCATGACCATTGCCCAAAGTGTACTGAGCTTTTCACTAAGTGCTCAGCATTGGCCTCCTGTTCTCATTTATTC
ATTTTATGAGATGGACTTGGACATCACTAATGCAAACACAGGATTCATAAATTATTCTGAAGTTTATTTAGTGCCTTGCCTCAATGGAGC
TTAAAGCATAGCACATAAATTTTATCTTATTTAGCCCTGGAGCATCACTAAGAAGCAGCTAGGAACTATGGCTTGCCAGACAGATTATGC
TTGTGCCAGAGAAGTGGAGAAGCCTGAAATCCCTTGTCAAGTATTCCACAGGAAGGAAAGGTAGTCTTTGGGCTTTGGTCTACTGACCTG
TGGATTAAACTCTATCCCTTAGATTATCCCATTTCTAAATACATTTATTCAATCAGTATTTCTATAATCACTTAGCATTTGATAGGCTTC
TTCCTTGATACATTTAACATAACGCCTCAGTTGCATATTACATTATGGAAGAATATACGATTGCTTCATATAACAACATTCTCATCACCA
GTGACAGTGTCCTACTGGTTTGAAGAAAGATATTCTTGGATTATGTGTTTTATATCTAAATGGTTATTCTGAGACTGGTTGTATTTTCTT

>80025_80025_1_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000309934_PHEX_chrX_22186429_ENST00000379374_length(amino acids)=526AA_BP=245
MLVEMSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTENYPNVLAFSF
LDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAG
KISSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLYQARAVLAKVGYPEFIMNDTHVNEDLK
AIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFT
HGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLL

--------------------------------------------------------------
>80025_80025_2_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000309934_PHEX_chrX_22186429_ENST00000418858_length(transcript)=2604nt_BP=1619nt
CTTTCTGTTTAAAATTTTGCCTGGATTTCTGATTATTTTTCTCAAGACAGGTATATATTTAAATTTATTGAGGTTAAAAGGTATGCCTTC
AGACTCTTGTTGAAATTGCCAAATCATTTTGAGAACTGTTTGTACCAGTTTTTACTTCCATCTGTACTTATGAGAATGCCAGACAGAAGT
ATTATTTTTTAAAAAGCTAATGTGGCTGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTGTGGCAGGCGCCTATAGTCCCAGCCACAT
CCTATGCTGTGGCATGGGAACCCAGGCTGAGGCATGAGAATTGCTTGAACCCTGGATGGGGGATGTTGCAGTCAGCCAAGATGGCGCCAC
TGCACTCCAGCCTGGGTGACAGAGCAAGATGCTGTCTCAAAAAAAAAAACAAAAAACAAAAAACAAAAGCTATATGTTAAGTGAAGCATA
GTATGTTGTTTTAATTAGTTTTTTGTTTTTTTTTTCCTCCTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAGCTCAGTGACGCGATT
TCGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCGGCCTCCTGAGTAGCTGGGATTACAGGTGTGCACCACCAC
GCCTGGCTAATTTTTGTATTTTTAGTAGAGAAGGGGTTTCATCATGTTGGCCAGGCTGGTCTCAAACTCCTGATCTTGTGATCCACCCTC
CTCAGCCACCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACACCTGGCCATTTTAATTACTATTCTTATATTACTAGTAAGTTGAACA
TTTTTACATATGCTTATCAAGTTTGGCTTTAATTTTTATGTAACCCAAATTGTTCATTTTGTTTTAGGTCTTCTCTGTTGGTTGAAATGT
CTATGATTTTATCTGCCTCAGTCATTCGTGTCAGAGATGGACTGCCACTTTCTGCTTCTACTGATTATGAACAAAGCACAGGAATGCAGG
AGTGCAGAAAGTATTTTAAAATGCTTTCGAGGAAACTTGCTCAACTTCCTGATAGATGTACACTGAAAACTGGACATTATAACATTAATT
TTATTAGCTCTCTGGGAGTGAGCTACATGATGTTGTGCACTGAAAATTACCCAAATGTTCTCGCCTTCTCTTTCCTGGATGAGCTTCAGA
AGGAGTTCATTACTACTTATAACATGATGAAGACAAATACTGCTGTCAGACCATACTGTTTCATTGAATTTGATAACTTCATTCAGAGGA
CCAAGCAGCGATATAATAATCCCAGGTCTCTTTCAACAAAGATAAATCTTTCTGACATGCAGACGGAAATCAAGCTGAGGCCTCCTTATC
AAATTTCCATGTGCGAACTGGGGTCAGCCAATGGAGTCACATCAGCATTTTCTGTTGACTGTAAAGGTGCTGGTAAGATTTCTTCTGCTC
ACCAGCGACTGGAACCAGCAACTCTGTCAGGGATTGTAGGATTTATCCTTAGTCTTTTATGTGGAGCTCTGAATTTAATTCGAGGCTTTC
ATGCTATAGAAAGTCTCCTGCAGAGTGATGGTGATGATTTTAATTACATCATTGCATTTTTCCTTGGAACAGCAGCCTGCCTTTACCAGG
CGAGAGCTGTTTTGGCAAAAGTTGGCTATCCAGAGTTTATAATGAATGATACTCATGTTAATGAAGACCTCAAAGCTATCAAGTTTTCAG
AAGCCGACTACTTTGGCAACGTCCTACAAACTCGCAAGTATTTAGCACAGTCTGATTTCTTCTGGCTAAGAAAAGCCGTTCCAAAAACAG
AGTGGTTTACAAATCCGACGACTGTCAATGCCTTCTACAGTGCATCCACCAACCAGATCCGATTTCCAGCAGGAGAGCTCCAGAAGCCTT
TCTTTTGGGGAACAGAATATCCTCGATCTCTGAGTTATGGTGCTATAGGAGTAATTGTCGGACATGAATTTACACATGGATTTGATAATA
ATGGTAGAAAATATGATAAAAATGGAAACCTGGATCCTTGGTGGTCTACTGAATCAGAAGAAAAGTTTAAGGAAAAAACAAAATGCATGA
TTAACCAGTATAGCAACTATTATTGGAAGAAAGCTGGCTTAAATGTCAAGGGGAAGAGGACCCTGGGAGAAAATATTGCTGATAATGGAG
GCCTGCGGGAAGCTTTTAGGGCTTACAGGAAATGGATAAATGACAGAAGGCAGGGACTTGAGGAGCCTCTTCTACCAGGCATCACATTCA
CCAACAACCAGCTCTTCTTCCTGAGTTATGCTCATGTGAGGTGCAATTCCTACAGACCAGAAGCTGCCCGAGAACAAGTCCAAATTGGTG
CTCACAGTCCCCCTCAGTTTAGGGTCAATGGTGCAATTAGTAACTTTGAAGAATTCCAGAAAGCTTTTAACTGTCCACCCAATTCCACGA
TGAACAGAGGCATGGACTCCTGCCGACTCTGGTAGCTGGGACGCTGGTTTATGGCATCCTGAGACAGTTGCACAGTGCCAGCGGAGGCTG

>80025_80025_2_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000309934_PHEX_chrX_22186429_ENST00000418858_length(amino acids)=526AA_BP=245
MLVEMSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTENYPNVLAFSF
LDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAG
KISSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLYQARAVLAKVGYPEFIMNDTHVNEDLK
AIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFT
HGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLL

--------------------------------------------------------------
>80025_80025_3_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000309934_PHEX_chrX_22186429_ENST00000535894_length(transcript)=2808nt_BP=1619nt
CTTTCTGTTTAAAATTTTGCCTGGATTTCTGATTATTTTTCTCAAGACAGGTATATATTTAAATTTATTGAGGTTAAAAGGTATGCCTTC
AGACTCTTGTTGAAATTGCCAAATCATTTTGAGAACTGTTTGTACCAGTTTTTACTTCCATCTGTACTTATGAGAATGCCAGACAGAAGT
ATTATTTTTTAAAAAGCTAATGTGGCTGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTGTGGCAGGCGCCTATAGTCCCAGCCACAT
CCTATGCTGTGGCATGGGAACCCAGGCTGAGGCATGAGAATTGCTTGAACCCTGGATGGGGGATGTTGCAGTCAGCCAAGATGGCGCCAC
TGCACTCCAGCCTGGGTGACAGAGCAAGATGCTGTCTCAAAAAAAAAAACAAAAAACAAAAAACAAAAGCTATATGTTAAGTGAAGCATA
GTATGTTGTTTTAATTAGTTTTTTGTTTTTTTTTTCCTCCTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAGCTCAGTGACGCGATT
TCGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCGGCCTCCTGAGTAGCTGGGATTACAGGTGTGCACCACCAC
GCCTGGCTAATTTTTGTATTTTTAGTAGAGAAGGGGTTTCATCATGTTGGCCAGGCTGGTCTCAAACTCCTGATCTTGTGATCCACCCTC
CTCAGCCACCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACACCTGGCCATTTTAATTACTATTCTTATATTACTAGTAAGTTGAACA
TTTTTACATATGCTTATCAAGTTTGGCTTTAATTTTTATGTAACCCAAATTGTTCATTTTGTTTTAGGTCTTCTCTGTTGGTTGAAATGT
CTATGATTTTATCTGCCTCAGTCATTCGTGTCAGAGATGGACTGCCACTTTCTGCTTCTACTGATTATGAACAAAGCACAGGAATGCAGG
AGTGCAGAAAGTATTTTAAAATGCTTTCGAGGAAACTTGCTCAACTTCCTGATAGATGTACACTGAAAACTGGACATTATAACATTAATT
TTATTAGCTCTCTGGGAGTGAGCTACATGATGTTGTGCACTGAAAATTACCCAAATGTTCTCGCCTTCTCTTTCCTGGATGAGCTTCAGA
AGGAGTTCATTACTACTTATAACATGATGAAGACAAATACTGCTGTCAGACCATACTGTTTCATTGAATTTGATAACTTCATTCAGAGGA
CCAAGCAGCGATATAATAATCCCAGGTCTCTTTCAACAAAGATAAATCTTTCTGACATGCAGACGGAAATCAAGCTGAGGCCTCCTTATC
AAATTTCCATGTGCGAACTGGGGTCAGCCAATGGAGTCACATCAGCATTTTCTGTTGACTGTAAAGGTGCTGGTAAGATTTCTTCTGCTC
ACCAGCGACTGGAACCAGCAACTCTGTCAGGGATTGTAGGATTTATCCTTAGTCTTTTATGTGGAGCTCTGAATTTAATTCGAGGCTTTC
ATGCTATAGAAAGTCTCCTGCAGAGTGATGGTGATGATTTTAATTACATCATTGCATTTTTCCTTGGAACAGCAGCCTGCCTTTACCAGG
CGAGAGCTGTTTTGGCAAAAGTTGGCTATCCAGAGTTTATAATGAATGATACTCATGTTAATGAAGACCTCAAAGCTATCAAGTTTTCAG
AAGCCGACTACTTTGGCAACGTCCTACAAACTCGCAAGTATTTAGCACAGTCTGATTTCTTCTGGCTAAGAAAAGCCGTTCCAAAAACAG
AGTGGTTTACAAATCCGACGACTGTCAATGCCTTCTACAGTGCATCCACCAACCAGATCCGATTTCCAGCAGGAGAGCTCCAGAAGCCTT
TCTTTTGGGGAACAGAATATCCTCGATCTCTGAGTTATGGTGCTATAGGAGTAATTGTCGGACATGAATTTACACATGGATTTGATAATA
ATGGTAGAAAATATGATAAAAATGGAAACCTGGATCCTTGGTGGTCTACTGAATCAGAAGAAAAGTTTAAGGAAAAAACAAAATGCATGA
TTAACCAGTATAGCAACTATTATTGGAAGAAAGCTGGCTTAAATGTCAAGGGGAAGAGGACCCTGGGAGAAAATATTGCTGATAATGGAG
GCCTGCGGGAAGCTTTTAGGGCTTACAGGAAATGGATAAATGACAGAAGGCAGGGACTTGAGGAGCCTCTTCTACCAGGCATCACATTCA
CCAACAACCAGCTCTTCTTCCTGAGTTATGCTCATGTGAGGTGCAATTCCTACAGACCAGAAGCTGCCCGAGAACAAGTCCAAATTGGTG
CTCACAGTCCCCCTCAGTTTAGGGTCAATGGTGCAATTAGTAACTTTGAAGAATTCCAGAAAGCTTTTAACTGTCCACCCAATTCCACGA
TGAACAGAGGCATGGACTCCTGCCGACTCTGGTAGCTGGGACGCTGGTTTATGGCATCCTGAGACAGTTGCACAGTGCCAGCGGAGGCTG
CACTGAGCCTTCATCGCCCATTGCTTTAGGCCTGGAGACTTTCATTTTTAGTGCATTTTCATTATTTGGGTAGGTGACCTGCTTGGATCT
AGACAGCATCTGTTCAAAGTTGTAGGGCTTATAAAGTGGAATATAAGAATGAACTAAGTATGTTTCTTTAGAAAATCAAACCAACAAAAA
TAAATCCCTAGGCTACTTTTGTTAAAATGCTATCTGCTAAATTGTTGCTATTGTCCATTTTAGGGTGTTGGCCACAGTTATGTGGTACAT

>80025_80025_3_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000309934_PHEX_chrX_22186429_ENST00000535894_length(amino acids)=526AA_BP=245
MLVEMSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTENYPNVLAFSF
LDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAG
KISSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLYQARAVLAKVGYPEFIMNDTHVNEDLK
AIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFT
HGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLL

--------------------------------------------------------------
>80025_80025_4_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000309934_PHEX_chrX_22186429_ENST00000537599_length(transcript)=2618nt_BP=1619nt
CTTTCTGTTTAAAATTTTGCCTGGATTTCTGATTATTTTTCTCAAGACAGGTATATATTTAAATTTATTGAGGTTAAAAGGTATGCCTTC
AGACTCTTGTTGAAATTGCCAAATCATTTTGAGAACTGTTTGTACCAGTTTTTACTTCCATCTGTACTTATGAGAATGCCAGACAGAAGT
ATTATTTTTTAAAAAGCTAATGTGGCTGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTGTGGCAGGCGCCTATAGTCCCAGCCACAT
CCTATGCTGTGGCATGGGAACCCAGGCTGAGGCATGAGAATTGCTTGAACCCTGGATGGGGGATGTTGCAGTCAGCCAAGATGGCGCCAC
TGCACTCCAGCCTGGGTGACAGAGCAAGATGCTGTCTCAAAAAAAAAAACAAAAAACAAAAAACAAAAGCTATATGTTAAGTGAAGCATA
GTATGTTGTTTTAATTAGTTTTTTGTTTTTTTTTTCCTCCTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAGCTCAGTGACGCGATT
TCGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCGGCCTCCTGAGTAGCTGGGATTACAGGTGTGCACCACCAC
GCCTGGCTAATTTTTGTATTTTTAGTAGAGAAGGGGTTTCATCATGTTGGCCAGGCTGGTCTCAAACTCCTGATCTTGTGATCCACCCTC
CTCAGCCACCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACACCTGGCCATTTTAATTACTATTCTTATATTACTAGTAAGTTGAACA
TTTTTACATATGCTTATCAAGTTTGGCTTTAATTTTTATGTAACCCAAATTGTTCATTTTGTTTTAGGTCTTCTCTGTTGGTTGAAATGT
CTATGATTTTATCTGCCTCAGTCATTCGTGTCAGAGATGGACTGCCACTTTCTGCTTCTACTGATTATGAACAAAGCACAGGAATGCAGG
AGTGCAGAAAGTATTTTAAAATGCTTTCGAGGAAACTTGCTCAACTTCCTGATAGATGTACACTGAAAACTGGACATTATAACATTAATT
TTATTAGCTCTCTGGGAGTGAGCTACATGATGTTGTGCACTGAAAATTACCCAAATGTTCTCGCCTTCTCTTTCCTGGATGAGCTTCAGA
AGGAGTTCATTACTACTTATAACATGATGAAGACAAATACTGCTGTCAGACCATACTGTTTCATTGAATTTGATAACTTCATTCAGAGGA
CCAAGCAGCGATATAATAATCCCAGGTCTCTTTCAACAAAGATAAATCTTTCTGACATGCAGACGGAAATCAAGCTGAGGCCTCCTTATC
AAATTTCCATGTGCGAACTGGGGTCAGCCAATGGAGTCACATCAGCATTTTCTGTTGACTGTAAAGGTGCTGGTAAGATTTCTTCTGCTC
ACCAGCGACTGGAACCAGCAACTCTGTCAGGGATTGTAGGATTTATCCTTAGTCTTTTATGTGGAGCTCTGAATTTAATTCGAGGCTTTC
ATGCTATAGAAAGTCTCCTGCAGAGTGATGGTGATGATTTTAATTACATCATTGCATTTTTCCTTGGAACAGCAGCCTGCCTTTACCAGG
CGAGAGCTGTTTTGGCAAAAGTTGGCTATCCAGAGTTTATAATGAATGATACTCATGTTAATGAAGACCTCAAAGCTATCAAGTTTTCAG
AAGCCGACTACTTTGGCAACGTCCTACAAACTCGCAAGTATTTAGCACAGTCTGATTTCTTCTGGCTAAGAAAAGCCGTTCCAAAAACAG
AGTGGTTTACAAATCCGACGACTGTCAATGCCTTCTACAGTGCATCCACCAACCAGATCCGATTTCCAGCAGGAGAGCTCCAGAAGCCTT
TCTTTTGGGGAACAGAATATCCTCGATCTCTGAGTTATGGTGCTATAGGAGTAATTGTCGGACATGAATTTACACATGGATTTGATAATA
ATGGTAGAAAATATGATAAAAATGGAAACCTGGATCCTTGGTGGTCTACTGAATCAGAAGAAAAGTTTAAGGAAAAAACAAAATGCATGA
TTAACCAGTATAGCAACTATTATTGGAAGAAAGCTGGCTTAAATGTCAAGGGGAAGAGGACCCTGGGAGAAAATATTGCTGATAATGGAG
GCCTGCGGGAAGCTTTTAGGGCTTACAGGAAATGGATAAATGACAGAAGGCAGGGACTTGAGGAGCCTCTTCTACCAGGCATCACATTCA
CCAACAACCAGCTCTTCTTCCTGAGTTATGCTCATGGTCAATGGTGCAATTAGTAACTTTGAAGAATTCCAGAAAGCTTTTAACTGTCCA
CCCAATTCCACGATGAACAGAGGCATGGACTCCTGCCGACTCTGGTAGCTGGGACGCTGGTTTATGGCATCCTGAGACAGTTGCACAGTG
CCAGCGGAGGCTGCACTGAGCCTTCATCGCCCATTGCTTTAGGCCTGGAGACTTTCATTTTTAGTGCATTTTCATTATTTGGGTAGGTGA
CCTGCTTGGATCTAGACAGCATCTGTTCAAAGTTGTAGGGCTTATAAAGTGGAATATAAGAATGAACTAAGTATGTTTCTTTAGAAAATC

>80025_80025_4_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000309934_PHEX_chrX_22186429_ENST00000537599_length(amino acids)=472AA_BP=245
MLVEMSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTENYPNVLAFSF
LDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAG
KISSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLYQARAVLAKVGYPEFIMNDTHVNEDLK
AIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFT
HGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLL

--------------------------------------------------------------
>80025_80025_5_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000492595_PHEX_chrX_22186429_ENST00000379374_length(transcript)=4974nt_BP=771nt
ACTCGGAGCGGCGGGTCCCGTCTCGACAGGTCTTCTCTGTTGGTTGAAATGTCTATGATTTTATCTGCCTCAGTCATTCGTGTCAGAGAT
GGACTGCCACTTTCTGCTTCTACTGATTATGAACAAAGCACAGGAATGCAGGAGTGCAGAAAGTATTTTAAAATGCTTTCGAGGAAACTT
GCTCAACTTCCTGATAGATGTACACTGAAAACTGGACATTATAACATTAATTTTATTAGCTCTCTGGGAGTGAGCTACATGATGTTGTGC
ACTGAAAATTACCCAAATGTTCTCGCCTTCTCTTTCCTGGATGAGCTTCAGAAGGAGTTCATTACTACTTATAACATGATGAAGACAAAT
ACTGCTGTCAGACCATACTGTTTCATTGAATTTGATAACTTCATTCAGAGGACCAAGCAGCGATATAATAATCCCAGGTCTCTTTCAACA
AAGATAAATCTTTCTGACATGCAGACGGAAATCAAGCTGAGGCCTCCTTATCAAATTTCCATGTGCGAACTGGGGTCAGCCAATGGAGTC
ACATCAGCATTTTCTGTTGACTGTAAAGGTGCTGGTAAGATTTCTTCTGCTCACCAGCGACTGGAACCAGCAACTCTGTCAGGGATTGTA
GGATTTATCCTTAGTCTTTTATGTGGAGCTCTGAATTTAATTCGAGGCTTTCATGCTATAGAAAGTCTCCTGCAGAGTGATGGTGATGAT
TTTAATTACATCATTGCATTTTTCCTTGGAACAGCAGCCTGCCTTTACCAGGCGAGAGCTGTTTTGGCAAAAGTTGGCTATCCAGAGTTT
ATAATGAATGATACTCATGTTAATGAAGACCTCAAAGCTATCAAGTTTTCAGAAGCCGACTACTTTGGCAACGTCCTACAAACTCGCAAG
TATTTAGCACAGTCTGATTTCTTCTGGCTAAGAAAAGCCGTTCCAAAAACAGAGTGGTTTACAAATCCGACGACTGTCAATGCCTTCTAC
AGTGCATCCACCAACCAGATCCGATTTCCAGCAGGAGAGCTCCAGAAGCCTTTCTTTTGGGGAACAGAATATCCTCGATCTCTGAGTTAT
GGTGCTATAGGAGTAATTGTCGGACATGAATTTACACATGGATTTGATAATAATGGTAGAAAATATGATAAAAATGGAAACCTGGATCCT
TGGTGGTCTACTGAATCAGAAGAAAAGTTTAAGGAAAAAACAAAATGCATGATTAACCAGTATAGCAACTATTATTGGAAGAAAGCTGGC
TTAAATGTCAAGGGGAAGAGGACCCTGGGAGAAAATATTGCTGATAATGGAGGCCTGCGGGAAGCTTTTAGGGCTTACAGGAAATGGATA
AATGACAGAAGGCAGGGACTTGAGGAGCCTCTTCTACCAGGCATCACATTCACCAACAACCAGCTCTTCTTCCTGAGTTATGCTCATGTG
AGGTGCAATTCCTACAGACCAGAAGCTGCCCGAGAACAAGTCCAAATTGGTGCTCACAGTCCCCCTCAGTTTAGGGTCAATGGTGCAATT
AGTAACTTTGAAGAATTCCAGAAAGCTTTTAACTGTCCACCCAATTCCACGATGAACAGAGGCATGGACTCCTGCCGACTCTGGTAGCTG
GGACGCTGGTTTATGGCATCCTGAGACAGTTGCACAGTGCCAGCGGAGGCTGCACTGAGCCTTCATCGCCCATTGCTTTAGGCCTGGAGA
CTTTCATTTTTAGTGCATTTTCATTATTTGGGTAGGTGACCTGCTTGGATCTAGACAGCATCTGTTCAAAGTTGTAGGGCTTATAAAGTG
GAATATAAGAATGAACTAAGTATGTTTCTTTAGAAAATCAAACCAACAAAAATAAATCCCTAGGCTACTTTTGTTAAAATGCTATCTGCT
AAATTGTTGCTATTGTCCATTTTAGGGTGTTGGCCACAGTTATGTGGTACATAGCATTTCAATCTATAGCTTTGTGGGAAGCCTAAATTG
ATGTATCCTTTAAAAGTTCAATCTATTAAACTTGTAGCCTCTCAATGATGAAGACATGTGCATGAATACCTGGGAGGGCTTGCTGCTCTG
TGGAATGCAGTGCACGTTTTTATGGACAGTAATTACACAGCATTCCTCAACTGTAAGGTAGTTAAATTAGAAATATGTTTGATCTCCATT
TTACACTTTTTGATGAAGTTCTTGCCTTCAGCTTTGGAGTCTGTTGGAATGAAACTGTGTCTCACAGCTTGCATCTGATGTAGCAGATTG
CCCTGTTCAAGTCAGCATGAACAAAGCTCGCAGAAAGGCTACTAGGTAACGGATTTGAGTTTATTCAGTAGAAAAAAAGGGAATGAGGAC
ATATCTTTAGGTCCCAGAAGCAGCAAAACCTCCTAGTTACATAACAGCAGGGAAACTAGGAGATGAAATCTCCAAAATTTTGTCCAGTCT
GTATGAACTGCAGTGATTGTCTGTCTGCTAGACACTTTTTTTTAGCCTAATTCTTGTTCGTTTCATTACCTTCATATGTGTGCATTGTAC
TGGTTTTGAAATGAGCAGACATTGAGAAAACAATTTTCTGATTCCCCATTAGGAACATATGATTTTCATTTCCCTTTAGTGCAAAGGAAC
AAACATCACATTGAGGAGGGAGAAGTGTACCCTTCTTTTTCAGCTTAATGTTACCTCTCTTTAAAAAAAAAACATTTTTGAAAAATTTCT
TGACTGATGACATTCTAGAATTTATTGATTCAATTTAAAATTCCCTGCATAGTCCAAATAAACATAATTTTTACTCTTCAAGTCATCTAA
AGAGTTGTGAGAAAGAGCAGTACTATGTGTTTTATCCTTAGAGCATTATCCTTCTAAGTGAACTCCTTTCTTATTACTGAGCGTGTGTGT
GTGTGTGTGTGTGTGTGTGTGTGTAGGATAAAATTGTAATGGCCTTAAAGTTGTTACCTGGCATTTTTGGTTTCTTAAAATAGGCATCCC
CCTACTCCCTTTACATTATTCATTAGACATGAGGTGCTGGGTTAAGTGGGCCAATAGGAAAATCTCAAAAGCAAAATGACAAATTCAGAT
TAACCACAGGAAGCCATTGTGTGTCCCTGTGATTTGTGATTCTTTTAAAAAAAAAAAAAATATATATATATATATATATATATATATATA
TGTATATCTACCTAAGTGTGTGCCATGTCCTTTTGTAGCCATGGGAACGTTTGAATGGAGAAAAATGGAGGGGCACCATCATGAGGAAAC
AATTATACTGCATTAGTCAGAGGAGAGCGATTTTCCCTTTGACTTCTTCCTCTCTGAATGGATAAACTTGTGAAGGGCAGCTACCTTGTC
CTCCTCTTAACCTGGCTTAATGTGACCTTAGTTTGTATTTCCAAAAACAAGCAGTATTAGGTTGGAATTGTATGTGTCTTTTCTCTGGAG
GAAGCATTCTGACTTGGTTTAGACATATAAGATACTCTGTTTTATTCCTGGACTTGGGTGTTTAAAATCAGCTGAGGTTTATCATGCTTA
TATGAATAGTGTTTCCCTTCTAGATTTCCTTTATAAACTCCAAATAAACACATTCCTGCAGGTCAGAGAAAGTGTTTGATAAAAGCATAG
AATTATGGCTTTGGAAAGACAAACTAAGTCACTTGTTGGTTTAGCAAAACTGGTTGGTGATTAGTTGGGGCCCTCACAGTTTCTAGATGA
GAAGCTTACCTTATCCTGATTAACTTTACTTGCTGTAACTGTTATACCGAAAATTGTAGGTAGGATGTCCATTACTCAAACAAAGCAGAA
CAAAACAACAAACCAAAAGCAGCAATACCAAATCATCACTACTAGCTAGAACAATGAGAAGGATTGAATTTCCAAATACATGCTTATGTT
TAACTCAACTCTTCCAATTACATTCTCATTGTCCTTTCTCTTGGATACCGATTGCTAAGATAAACAGACACTGATTAAGTGGTAGAAAGA
GAAAGGTAAAATGCAACTGGAAGGGAAAGAAAAAAGTAGGGAGAAGCTGGCCTATGGATGTGGCTTTGAAGAGAAGACAGGATTTTGGCA
TTCCTTGCTAAGCACGTTCAATGGAGGAGAGCCATGAAGTTTTACAAAAATAATTATGGTAAATTAAAAGGATATTAGATATTGGATCTC
AGACTAGGGCTGCTATAATACAGTTCTCTGATTCGCACACCAGATGTTCTGCCAGCGAACTGTTGTCTGGGCATTGGAAGGAGTTAGGTT
TTTTGTGTTTGTGAAAATCTCCTGGATTAGTAAAAAAATTTTCTAGATATAAAGTGGTTTTATTTGGGCTCATGACCATTGCCCAAAGTG
TACTGAGCTTTTCACTAAGTGCTCAGCATTGGCCTCCTGTTCTCATTTATTCATTTTATGAGATGGACTTGGACATCACTAATGCAAACA
CAGGATTCATAAATTATTCTGAAGTTTATTTAGTGCCTTGCCTCAATGGAGCTTAAAGCATAGCACATAAATTTTATCTTATTTAGCCCT
GGAGCATCACTAAGAAGCAGCTAGGAACTATGGCTTGCCAGACAGATTATGCTTGTGCCAGAGAAGTGGAGAAGCCTGAAATCCCTTGTC
AAGTATTCCACAGGAAGGAAAGGTAGTCTTTGGGCTTTGGTCTACTGACCTGTGGATTAAACTCTATCCCTTAGATTATCCCATTTCTAA
ATACATTTATTCAATCAGTATTTCTATAATCACTTAGCATTTGATAGGCTTCTTCCTTGATACATTTAACATAACGCCTCAGTTGCATAT
TACATTATGGAAGAATATACGATTGCTTCATATAACAACATTCTCATCACCAGTGACAGTGTCCTACTGGTTTGAAGAAAGATATTCTTG
GATTATGTGTTTTATATCTAAATGGTTATTCTGAGACTGGTTGTATTTTCTTCTCCTACTCGTGAAACGATGTGAACAAGCATTTTAAGG

>80025_80025_5_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000492595_PHEX_chrX_22186429_ENST00000379374_length(amino acids)=526AA_BP=245
MLVEMSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTENYPNVLAFSF
LDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAG
KISSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLYQARAVLAKVGYPEFIMNDTHVNEDLK
AIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFT
HGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLL

--------------------------------------------------------------
>80025_80025_6_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000492595_PHEX_chrX_22186429_ENST00000418858_length(transcript)=1756nt_BP=771nt
ACTCGGAGCGGCGGGTCCCGTCTCGACAGGTCTTCTCTGTTGGTTGAAATGTCTATGATTTTATCTGCCTCAGTCATTCGTGTCAGAGAT
GGACTGCCACTTTCTGCTTCTACTGATTATGAACAAAGCACAGGAATGCAGGAGTGCAGAAAGTATTTTAAAATGCTTTCGAGGAAACTT
GCTCAACTTCCTGATAGATGTACACTGAAAACTGGACATTATAACATTAATTTTATTAGCTCTCTGGGAGTGAGCTACATGATGTTGTGC
ACTGAAAATTACCCAAATGTTCTCGCCTTCTCTTTCCTGGATGAGCTTCAGAAGGAGTTCATTACTACTTATAACATGATGAAGACAAAT
ACTGCTGTCAGACCATACTGTTTCATTGAATTTGATAACTTCATTCAGAGGACCAAGCAGCGATATAATAATCCCAGGTCTCTTTCAACA
AAGATAAATCTTTCTGACATGCAGACGGAAATCAAGCTGAGGCCTCCTTATCAAATTTCCATGTGCGAACTGGGGTCAGCCAATGGAGTC
ACATCAGCATTTTCTGTTGACTGTAAAGGTGCTGGTAAGATTTCTTCTGCTCACCAGCGACTGGAACCAGCAACTCTGTCAGGGATTGTA
GGATTTATCCTTAGTCTTTTATGTGGAGCTCTGAATTTAATTCGAGGCTTTCATGCTATAGAAAGTCTCCTGCAGAGTGATGGTGATGAT
TTTAATTACATCATTGCATTTTTCCTTGGAACAGCAGCCTGCCTTTACCAGGCGAGAGCTGTTTTGGCAAAAGTTGGCTATCCAGAGTTT
ATAATGAATGATACTCATGTTAATGAAGACCTCAAAGCTATCAAGTTTTCAGAAGCCGACTACTTTGGCAACGTCCTACAAACTCGCAAG
TATTTAGCACAGTCTGATTTCTTCTGGCTAAGAAAAGCCGTTCCAAAAACAGAGTGGTTTACAAATCCGACGACTGTCAATGCCTTCTAC
AGTGCATCCACCAACCAGATCCGATTTCCAGCAGGAGAGCTCCAGAAGCCTTTCTTTTGGGGAACAGAATATCCTCGATCTCTGAGTTAT
GGTGCTATAGGAGTAATTGTCGGACATGAATTTACACATGGATTTGATAATAATGGTAGAAAATATGATAAAAATGGAAACCTGGATCCT
TGGTGGTCTACTGAATCAGAAGAAAAGTTTAAGGAAAAAACAAAATGCATGATTAACCAGTATAGCAACTATTATTGGAAGAAAGCTGGC
TTAAATGTCAAGGGGAAGAGGACCCTGGGAGAAAATATTGCTGATAATGGAGGCCTGCGGGAAGCTTTTAGGGCTTACAGGAAATGGATA
AATGACAGAAGGCAGGGACTTGAGGAGCCTCTTCTACCAGGCATCACATTCACCAACAACCAGCTCTTCTTCCTGAGTTATGCTCATGTG
AGGTGCAATTCCTACAGACCAGAAGCTGCCCGAGAACAAGTCCAAATTGGTGCTCACAGTCCCCCTCAGTTTAGGGTCAATGGTGCAATT
AGTAACTTTGAAGAATTCCAGAAAGCTTTTAACTGTCCACCCAATTCCACGATGAACAGAGGCATGGACTCCTGCCGACTCTGGTAGCTG
GGACGCTGGTTTATGGCATCCTGAGACAGTTGCACAGTGCCAGCGGAGGCTGCACTGAGCCTTCATCGCCCATTGCTTTAGGCCTGGAGA

>80025_80025_6_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000492595_PHEX_chrX_22186429_ENST00000418858_length(amino acids)=526AA_BP=245
MLVEMSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTENYPNVLAFSF
LDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAG
KISSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLYQARAVLAKVGYPEFIMNDTHVNEDLK
AIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFT
HGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLL

--------------------------------------------------------------
>80025_80025_7_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000492595_PHEX_chrX_22186429_ENST00000535894_length(transcript)=1960nt_BP=771nt
ACTCGGAGCGGCGGGTCCCGTCTCGACAGGTCTTCTCTGTTGGTTGAAATGTCTATGATTTTATCTGCCTCAGTCATTCGTGTCAGAGAT
GGACTGCCACTTTCTGCTTCTACTGATTATGAACAAAGCACAGGAATGCAGGAGTGCAGAAAGTATTTTAAAATGCTTTCGAGGAAACTT
GCTCAACTTCCTGATAGATGTACACTGAAAACTGGACATTATAACATTAATTTTATTAGCTCTCTGGGAGTGAGCTACATGATGTTGTGC
ACTGAAAATTACCCAAATGTTCTCGCCTTCTCTTTCCTGGATGAGCTTCAGAAGGAGTTCATTACTACTTATAACATGATGAAGACAAAT
ACTGCTGTCAGACCATACTGTTTCATTGAATTTGATAACTTCATTCAGAGGACCAAGCAGCGATATAATAATCCCAGGTCTCTTTCAACA
AAGATAAATCTTTCTGACATGCAGACGGAAATCAAGCTGAGGCCTCCTTATCAAATTTCCATGTGCGAACTGGGGTCAGCCAATGGAGTC
ACATCAGCATTTTCTGTTGACTGTAAAGGTGCTGGTAAGATTTCTTCTGCTCACCAGCGACTGGAACCAGCAACTCTGTCAGGGATTGTA
GGATTTATCCTTAGTCTTTTATGTGGAGCTCTGAATTTAATTCGAGGCTTTCATGCTATAGAAAGTCTCCTGCAGAGTGATGGTGATGAT
TTTAATTACATCATTGCATTTTTCCTTGGAACAGCAGCCTGCCTTTACCAGGCGAGAGCTGTTTTGGCAAAAGTTGGCTATCCAGAGTTT
ATAATGAATGATACTCATGTTAATGAAGACCTCAAAGCTATCAAGTTTTCAGAAGCCGACTACTTTGGCAACGTCCTACAAACTCGCAAG
TATTTAGCACAGTCTGATTTCTTCTGGCTAAGAAAAGCCGTTCCAAAAACAGAGTGGTTTACAAATCCGACGACTGTCAATGCCTTCTAC
AGTGCATCCACCAACCAGATCCGATTTCCAGCAGGAGAGCTCCAGAAGCCTTTCTTTTGGGGAACAGAATATCCTCGATCTCTGAGTTAT
GGTGCTATAGGAGTAATTGTCGGACATGAATTTACACATGGATTTGATAATAATGGTAGAAAATATGATAAAAATGGAAACCTGGATCCT
TGGTGGTCTACTGAATCAGAAGAAAAGTTTAAGGAAAAAACAAAATGCATGATTAACCAGTATAGCAACTATTATTGGAAGAAAGCTGGC
TTAAATGTCAAGGGGAAGAGGACCCTGGGAGAAAATATTGCTGATAATGGAGGCCTGCGGGAAGCTTTTAGGGCTTACAGGAAATGGATA
AATGACAGAAGGCAGGGACTTGAGGAGCCTCTTCTACCAGGCATCACATTCACCAACAACCAGCTCTTCTTCCTGAGTTATGCTCATGTG
AGGTGCAATTCCTACAGACCAGAAGCTGCCCGAGAACAAGTCCAAATTGGTGCTCACAGTCCCCCTCAGTTTAGGGTCAATGGTGCAATT
AGTAACTTTGAAGAATTCCAGAAAGCTTTTAACTGTCCACCCAATTCCACGATGAACAGAGGCATGGACTCCTGCCGACTCTGGTAGCTG
GGACGCTGGTTTATGGCATCCTGAGACAGTTGCACAGTGCCAGCGGAGGCTGCACTGAGCCTTCATCGCCCATTGCTTTAGGCCTGGAGA
CTTTCATTTTTAGTGCATTTTCATTATTTGGGTAGGTGACCTGCTTGGATCTAGACAGCATCTGTTCAAAGTTGTAGGGCTTATAAAGTG
GAATATAAGAATGAACTAAGTATGTTTCTTTAGAAAATCAAACCAACAAAAATAAATCCCTAGGCTACTTTTGTTAAAATGCTATCTGCT

>80025_80025_7_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000492595_PHEX_chrX_22186429_ENST00000535894_length(amino acids)=526AA_BP=245
MLVEMSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTENYPNVLAFSF
LDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAG
KISSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLYQARAVLAKVGYPEFIMNDTHVNEDLK
AIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFT
HGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLL

--------------------------------------------------------------
>80025_80025_8_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000492595_PHEX_chrX_22186429_ENST00000537599_length(transcript)=1770nt_BP=771nt
ACTCGGAGCGGCGGGTCCCGTCTCGACAGGTCTTCTCTGTTGGTTGAAATGTCTATGATTTTATCTGCCTCAGTCATTCGTGTCAGAGAT
GGACTGCCACTTTCTGCTTCTACTGATTATGAACAAAGCACAGGAATGCAGGAGTGCAGAAAGTATTTTAAAATGCTTTCGAGGAAACTT
GCTCAACTTCCTGATAGATGTACACTGAAAACTGGACATTATAACATTAATTTTATTAGCTCTCTGGGAGTGAGCTACATGATGTTGTGC
ACTGAAAATTACCCAAATGTTCTCGCCTTCTCTTTCCTGGATGAGCTTCAGAAGGAGTTCATTACTACTTATAACATGATGAAGACAAAT
ACTGCTGTCAGACCATACTGTTTCATTGAATTTGATAACTTCATTCAGAGGACCAAGCAGCGATATAATAATCCCAGGTCTCTTTCAACA
AAGATAAATCTTTCTGACATGCAGACGGAAATCAAGCTGAGGCCTCCTTATCAAATTTCCATGTGCGAACTGGGGTCAGCCAATGGAGTC
ACATCAGCATTTTCTGTTGACTGTAAAGGTGCTGGTAAGATTTCTTCTGCTCACCAGCGACTGGAACCAGCAACTCTGTCAGGGATTGTA
GGATTTATCCTTAGTCTTTTATGTGGAGCTCTGAATTTAATTCGAGGCTTTCATGCTATAGAAAGTCTCCTGCAGAGTGATGGTGATGAT
TTTAATTACATCATTGCATTTTTCCTTGGAACAGCAGCCTGCCTTTACCAGGCGAGAGCTGTTTTGGCAAAAGTTGGCTATCCAGAGTTT
ATAATGAATGATACTCATGTTAATGAAGACCTCAAAGCTATCAAGTTTTCAGAAGCCGACTACTTTGGCAACGTCCTACAAACTCGCAAG
TATTTAGCACAGTCTGATTTCTTCTGGCTAAGAAAAGCCGTTCCAAAAACAGAGTGGTTTACAAATCCGACGACTGTCAATGCCTTCTAC
AGTGCATCCACCAACCAGATCCGATTTCCAGCAGGAGAGCTCCAGAAGCCTTTCTTTTGGGGAACAGAATATCCTCGATCTCTGAGTTAT
GGTGCTATAGGAGTAATTGTCGGACATGAATTTACACATGGATTTGATAATAATGGTAGAAAATATGATAAAAATGGAAACCTGGATCCT
TGGTGGTCTACTGAATCAGAAGAAAAGTTTAAGGAAAAAACAAAATGCATGATTAACCAGTATAGCAACTATTATTGGAAGAAAGCTGGC
TTAAATGTCAAGGGGAAGAGGACCCTGGGAGAAAATATTGCTGATAATGGAGGCCTGCGGGAAGCTTTTAGGGCTTACAGGAAATGGATA
AATGACAGAAGGCAGGGACTTGAGGAGCCTCTTCTACCAGGCATCACATTCACCAACAACCAGCTCTTCTTCCTGAGTTATGCTCATGGT
CAATGGTGCAATTAGTAACTTTGAAGAATTCCAGAAAGCTTTTAACTGTCCACCCAATTCCACGATGAACAGAGGCATGGACTCCTGCCG
ACTCTGGTAGCTGGGACGCTGGTTTATGGCATCCTGAGACAGTTGCACAGTGCCAGCGGAGGCTGCACTGAGCCTTCATCGCCCATTGCT
TTAGGCCTGGAGACTTTCATTTTTAGTGCATTTTCATTATTTGGGTAGGTGACCTGCTTGGATCTAGACAGCATCTGTTCAAAGTTGTAG

>80025_80025_8_SEC22A-PHEX_SEC22A_chr3_122978436_ENST00000492595_PHEX_chrX_22186429_ENST00000537599_length(amino acids)=472AA_BP=245
MLVEMSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTENYPNVLAFSF
LDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAG
KISSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLYQARAVLAKVGYPEFIMNDTHVNEDLK
AIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFT
HGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SEC22A-PHEX


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for SEC22A-PHEX


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for SEC22A-PHEX


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource