FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:SEC31A-PTEN (FusionGDB2 ID:80116)

Fusion Gene Summary for SEC31A-PTEN

check button Fusion gene summary
Fusion gene informationFusion gene name: SEC31A-PTEN
Fusion gene ID: 80116
HgeneTgene
Gene symbol

SEC31A

PTEN

Gene ID

22872

5728

Gene nameSEC31 homolog A, COPII coat complex componentphosphatase and tensin homolog
SynonymsABP125|ABP130|HSPC275|HSPC334|NEDSOSB|SEC31L110q23del|BZS|CWS1|DEC|GLM2|MHAM|MMAC1|PTEN1|PTENbeta|TEP1
Cytomap

4q21.22

10q23.31

Type of geneprotein-codingprotein-coding
Descriptionprotein transport protein Sec31ASEC31 homolog A, COPII coating complex componentSEC31-like protein 1SEC31-related protein Aweb1-like proteinyeast Sec31p homologphosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENMMAC1 phosphatase and tensin homolog deleted on chromosome 10PTENepsilonmitochondrial PTENalphamitochondrial phosphatase and tensin protein alphamutat
Modification date2020031320200329
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000311785, ENST00000326950, 
ENST00000348405, ENST00000355196, 
ENST00000395310, ENST00000432794, 
ENST00000443462, ENST00000448323, 
ENST00000500777, ENST00000505472, 
ENST00000505984, ENST00000508479, 
ENST00000508502, ENST00000509142, 
ENST00000513858, ENST00000436790, 
ENST00000264405, 		ENST00000472832, 
ENST00000371953, 
Fusion gene scores* DoF score22 X 23 X 10=506030 X 21 X 10=6300
# samples 2536
** MAII scorelog2(25/5060*10)=-4.33913738491959
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(36/6300*10)=-4.12928301694497
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SEC31A [Title/Abstract] AND PTEN [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSEC31A(83799881)-PTEN(89725042), # samples:1
Anticipated loss of major functional domain due to fusion event.SEC31A-PTEN seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
SEC31A-PTEN seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
SEC31A-PTEN seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
SEC31A-PTEN seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
SEC31A-PTEN seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSEC31A

GO:0051592

response to calcium ion

17196169

HgeneSEC31A

GO:0090110

cargo loading into COPII-coated vesicle

17499046|18843296

TgenePTEN

GO:0001933

negative regulation of protein phosphorylation

20123964

TgenePTEN

GO:0006470

protein dephosphorylation

9256433

TgenePTEN

GO:0008285

negative regulation of cell proliferation

19057511

TgenePTEN

GO:0045736

negative regulation of cyclin-dependent protein serine/threonine kinase activity

21241890

TgenePTEN

GO:0046855

inositol phosphate dephosphorylation

9593664

TgenePTEN

GO:0046856

phosphatidylinositol dephosphorylation

9593664|9811831

TgenePTEN

GO:0050821

protein stabilization

20123964

TgenePTEN

GO:0060070

canonical Wnt signaling pathway

20123964

TgenePTEN

GO:1902807

negative regulation of cell cycle G1/S phase transition

10918569

TgenePTEN

GO:1904668

positive regulation of ubiquitin protein ligase activity

21241890

TgenePTEN

GO:2000060

positive regulation of ubiquitin-dependent protein catabolic process

21241890

TgenePTEN

GO:2000134

negative regulation of G1/S transition of mitotic cell cycle

21241890


check buttonFusion gene breakpoints across SEC31A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PTEN (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABI823499SEC31Achr4

83799881

-PTENchr10

89725042

+


Top

Fusion Gene ORF analysis for SEC31A-PTEN

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000311785ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000326950ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000348405ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000355196ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000395310ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000432794ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000443462ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000448323ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000500777ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000505472ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000505984ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000508479ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000508502ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000509142ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5CDS-intronENST00000513858ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
5UTR-3CDSENST00000436790ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
5UTR-intronENST00000436790ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000311785ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000326950ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000348405ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000395310ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000432794ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000443462ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000448323ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000500777ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000505472ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000505984ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000508479ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000508502ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000509142ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
Frame-shiftENST00000513858ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
In-frameENST00000355196ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
intron-3CDSENST00000264405ENST00000371953SEC31Achr4

83799881

-PTENchr10

89725042

+
intron-intronENST00000264405ENST00000472832SEC31Achr4

83799881

-PTENchr10

89725042

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000355196SEC31Achr483799881-ENST00000371953PTENchr1089725042+7424780378965195

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000355196ENST00000371953SEC31Achr483799881-PTENchr1089725042+0.0006947650.99930525

Top

Fusion Genomic Features for SEC31A-PTEN


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SEC31Achr483799882-PTENchr1089725043+7.28E-101
SEC31Achr483799882-PTENchr1089725043+7.28E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for SEC31A-PTEN


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:83799881/chr10:89725042)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSEC31Achr4:83799881chr10:89725042ENST00000311785-4264_471341107.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000311785-42668_1111341107.0RepeatNote=WD 2
HgeneSEC31Achr4:83799881chr10:89725042ENST00000326950-4254_471341182.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000326950-42568_1111341182.0RepeatNote=WD 2
HgeneSEC31Achr4:83799881chr10:89725042ENST00000348405-4254_471341182.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000348405-42568_1111341182.0RepeatNote=WD 2
HgeneSEC31Achr4:83799881chr10:89725042ENST00000355196-6294_471341221.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000355196-62968_1111341221.0RepeatNote=WD 2
HgeneSEC31Achr4:83799881chr10:89725042ENST00000395310-4274_471341221.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000395310-42768_1111341221.0RepeatNote=WD 2
HgeneSEC31Achr4:83799881chr10:89725042ENST00000432794-4284_471341234.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000432794-42868_1111341234.0RepeatNote=WD 2
HgeneSEC31Achr4:83799881chr10:89725042ENST00000443462-3264_471291201.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000443462-32668_1111291201.0RepeatNote=WD 2
HgeneSEC31Achr4:83799881chr10:89725042ENST00000448323-4274_471341221.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000448323-42768_1111341221.0RepeatNote=WD 2
HgeneSEC31Achr4:83799881chr10:89725042ENST00000500777-3234_471341068.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000500777-32368_1111341068.0RepeatNote=WD 2
HgeneSEC31Achr4:83799881chr10:89725042ENST00000508502-4274_471341206.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000508502-42768_1111341206.0RepeatNote=WD 2
HgeneSEC31Achr4:83799881chr10:89725042ENST00000509142-4264_471341107.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000509142-42668_1111341107.0RepeatNote=WD 2
HgeneSEC31Achr4:83799881chr10:89725042ENST00000513858-4244_471341068.0RepeatNote=WD 1
HgeneSEC31Achr4:83799881chr10:89725042ENST00000513858-42468_1111341068.0RepeatNote=WD 2
TgenePTENchr4:83799881chr10:89725042ENST0000037195379401_403342404.0RegionNote=PDZ domain-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSEC31Achr4:83799881chr10:89725042ENST00000311785-426800_10911341107.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000326950-425800_10911341182.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000348405-425800_10911341182.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000355196-629800_10911341221.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000395310-427800_10911341221.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000432794-428800_10911341234.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000443462-326800_10911291201.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000448323-427800_10911341221.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000500777-323800_10911341068.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000508502-427800_10911341206.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000509142-426800_10911341107.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000513858-424800_10911341068.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83799881chr10:89725042ENST00000311785-426842_8481341107.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000326950-425842_8481341182.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000348405-425842_8481341182.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000355196-629842_8481341221.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000395310-427842_8481341221.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000432794-428842_8481341234.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000443462-326842_8481291201.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000448323-427842_8481341221.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000500777-323842_8481341068.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000508502-427842_8481341206.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000509142-426842_8481341107.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000513858-424842_8481341068.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83799881chr10:89725042ENST00000311785-426120_1601341107.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000311785-426166_2061341107.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000311785-426209_2541341107.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000311785-426258_2981341107.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000311785-426301_3421341107.0RepeatNote=WD 7
HgeneSEC31Achr4:83799881chr10:89725042ENST00000326950-425120_1601341182.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000326950-425166_2061341182.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000326950-425209_2541341182.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000326950-425258_2981341182.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000326950-425301_3421341182.0RepeatNote=WD 7
HgeneSEC31Achr4:83799881chr10:89725042ENST00000348405-425120_1601341182.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000348405-425166_2061341182.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000348405-425209_2541341182.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000348405-425258_2981341182.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000348405-425301_3421341182.0RepeatNote=WD 7
HgeneSEC31Achr4:83799881chr10:89725042ENST00000355196-629120_1601341221.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000355196-629166_2061341221.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000355196-629209_2541341221.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000355196-629258_2981341221.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000355196-629301_3421341221.0RepeatNote=WD 7
HgeneSEC31Achr4:83799881chr10:89725042ENST00000395310-427120_1601341221.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000395310-427166_2061341221.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000395310-427209_2541341221.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000395310-427258_2981341221.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000395310-427301_3421341221.0RepeatNote=WD 7
HgeneSEC31Achr4:83799881chr10:89725042ENST00000432794-428120_1601341234.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000432794-428166_2061341234.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000432794-428209_2541341234.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000432794-428258_2981341234.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000432794-428301_3421341234.0RepeatNote=WD 7
HgeneSEC31Achr4:83799881chr10:89725042ENST00000443462-326120_1601291201.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000443462-326166_2061291201.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000443462-326209_2541291201.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000443462-326258_2981291201.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000443462-326301_3421291201.0RepeatNote=WD 7
HgeneSEC31Achr4:83799881chr10:89725042ENST00000448323-427120_1601341221.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000448323-427166_2061341221.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000448323-427209_2541341221.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000448323-427258_2981341221.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000448323-427301_3421341221.0RepeatNote=WD 7
HgeneSEC31Achr4:83799881chr10:89725042ENST00000500777-323120_1601341068.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000500777-323166_2061341068.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000500777-323209_2541341068.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000500777-323258_2981341068.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000500777-323301_3421341068.0RepeatNote=WD 7
HgeneSEC31Achr4:83799881chr10:89725042ENST00000508502-427120_1601341206.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000508502-427166_2061341206.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000508502-427209_2541341206.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000508502-427258_2981341206.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000508502-427301_3421341206.0RepeatNote=WD 7
HgeneSEC31Achr4:83799881chr10:89725042ENST00000509142-426120_1601341107.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000509142-426166_2061341107.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000509142-426209_2541341107.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000509142-426258_2981341107.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000509142-426301_3421341107.0RepeatNote=WD 7
HgeneSEC31Achr4:83799881chr10:89725042ENST00000513858-424120_1601341068.0RepeatNote=WD 3
HgeneSEC31Achr4:83799881chr10:89725042ENST00000513858-424166_2061341068.0RepeatNote=WD 4
HgeneSEC31Achr4:83799881chr10:89725042ENST00000513858-424209_2541341068.0RepeatNote=WD 5
HgeneSEC31Achr4:83799881chr10:89725042ENST00000513858-424258_2981341068.0RepeatNote=WD 6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000513858-424301_3421341068.0RepeatNote=WD 7
TgenePTENchr4:83799881chr10:89725042ENST000003719537914_185342404.0DomainPhosphatase tensin-type
TgenePTENchr4:83799881chr10:89725042ENST0000037195379190_350342404.0DomainC2 tensin-type


Top

Fusion Gene Sequence for SEC31A-PTEN


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80116_80116_1_SEC31A-PTEN_SEC31A_chr4_83799881_ENST00000355196_PTEN_chr10_89725042_ENST00000371953_length(transcript)=7424nt_BP=780nt
GCGGAATAGTGGGTTTTGCTGCAACCGGTTTATTTTCCTTCTGTTTTCACCCATTCTGGCACAATCTGGCGCCATCGTCCTTCTTGTGAG
GCCAAGCCTGAAAATGCGAAGCAGAGAGGCAGGACCAAAATTGAGGCGAATCCAGGAACCTGCCAATGGGTCTCCGGGTGCGGTCTCTGA
AACTGGAGGATATCGGGAGGAAAGGCTCTCCGATGCGGAGATAATGGGGAAGCTCTTGGCATGGTTGGCTGTAGGTATGTGATACCGGAG
GAGCAGGAGTCAAATAGGATACGCCGACTTTTAATTCAAGGAACCCTTTTCTGAAACACTTTGCCACAATGAAGGAAATAAGATTACAGC
CGAAGATACATATTAAGGATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTA
GCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCC
TTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGAT
GTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTG
ATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGGTGAAGCTGTACTTCACAAAAACAGTAGAG
GAGCCGTCAAATCCAGAGGCTAGCAGTTCAACTTCTGTAACACCAGATGTTAGTGACAATGAACCTGATCATTATAGATATTCTGACACC
ACTGACTCTGATCCAGAGAATGAACCTTTTGATGAAGATCAGCATACACAAATTACAAAAGTCTGAATTTTTTTTTATCAAGAGGGATAA
AACACCATGAAAATAAACTTGAATAAACTGAAAATGGACCTTTTTTTTTTTAATGGCAATAGGACATTGTGTCAGATTACCAGTTATAGG
AACAATTCTCTTTTCCTGACCAATCTTGTTTTACCCTATACATCCACAGGGTTTTGACACTTGTTGTCCAGTTGAAAAAAGGTTGTGTAG
CTGTGTCATGTATATACCTTTTTGTGTCAAAAGGACATTTAAAATTCAATTAGGATTAATAAAGATGGCACTTTCCCGTTTTATTCCAGT
TTTATAAAAAGTGGAGACAGACTGATGTGTATACGTAGGAATTTTTTCCTTTTGTGTTCTGTCACCAACTGAAGTGGCTAAAGAGCTTTG
TGATATACTGGTTCACATCCTACCCCTTTGCACTTGTGGCAACAGATAAGTTTGCAGTTGGCTAAGAGAGGTTTCCGAAGGGTTTTGCTA
CATTCTAATGCATGTATTCGGGTTAGGGGAATGGAGGGAATGCTCAGAAAGGAAATAATTTTATGCTGGACTCTGGACCATATACCATCT
CCAGCTATTTACACACACCTTTCTTTAGCATGCTACAGTTATTAATCTGGACATTCGAGGAATTGGCCGCTGTCACTGCTTGTTGTTTGC
GCATTTTTTTTTAAAGCATATTGGTGCTAGAAAAGGCAGCTAAAGGAAGTGAATCTGTATTGGGGTACAGGAATGAACCTTCTGCAACAT
CTTAAGATCCACAAATGAAGGGATATAAAAATAATGTCATAGGTAAGAAACACAGCAACAATGACTTAACCATATAAATGTGGAGGCTAT
CAACAAAGAATGGGCTTGAAACATTATAAAAATTGACAATGATTTATTAAATATGTTTTCTCAATTGTAACGACTTCTCCATCTCCTGTG
TAATCAAGGCCAGTGCTAAAATTCAGATGCTGTTAGTACCTACATCAGTCAACAACTTACACTTATTTTACTAGTTTTCAATCATAATAC
CTGCTGTGGATGCTTCATGTGCTGCCTGCAAGCTTCTTTTTTCTCATTAAATATAAAATATTTTGTAATGCTGCACAGAAATTTTCAATT
TGAGATTCTACAGTAAGCGTTTTTTTTCTTTGAAGATTTATGATGCACTTATTCAATAGCTGTCAGCCGTTCCACCCTTTTGACCTTACA
CATTCTATTACAATGAATTTTGCAGTTTTGCACATTTTTTAAATGTCATTAACTGTTAGGGAATTTTACTTGAATACTGAATACATATAA
TGTTTATATTAAAAAGGACATTTGTGTTAAAAAGGAAATTAGAGTTGCAGTAAACTTTCAATGCTGCACACAAAAAAAAGACATTTGATT
TTTCAGTAGAAATTGTCCTACATGTGCTTTATTGATTTGCTATTGAAAGAATAGGGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAATG
TGCAGTGTTGAATCATTTCTTCATAGTGCTCCCCCGAGTTGGGACTAGGGCTTCAATTTCACTTCTTAAAAAAAATCATCATATATTTGA
TATGCCCAGACTGCATACGATTTTAAGCGGAGTACAACTACTATTGTAAAGCTAATGTGAAGATATTATTAAAAAGGTTTTTTTTTCCAG
AAATTTGGTGTCTTCAAATTATACCTTCACCTTGACATTTGAATATCCAGCCATTTTGTTTCTTAATGGTATAAAATTCCATTTTCAATA
ACTTATTGGTGCTGAAATTGTTCACTAGCTGTGGTCTGACCTAGTTAATTTACAAATACAGATTGAATAGGACCTACTAGAGCAGCATTT
ATAGAGTTTGATGGCAAATAGATTAGGCAGAACTTCATCTAAAATATTCTTAGTAAATAATGTTGACACGTTTTCCATACCTTGTCAGTT
TCATTCAACAATTTTTAAATTTTTAACAAAGCTCTTAGGATTTACACATTTATATTTAAACATTGATATATAGAGTATTGATTGATTGCT
CATAAGTTAAATTGGTAAAGTTAGAGACAACTATTCTAACACCTCACCATTGAAATTTATATGCCACCTTGTCTTTCATAAAAGCTGAAA
ATTGTTACCTAAAATGAAAATCAACTTCATGTTTTGAAGATAGTTATAAATATTGTTCTTTGTTACAATTTCGGGCACCGCATATTAAAA
CGTAACTTTATTGTTCCAATATGTAACATGGAGGGCCAGGTCATAAATAATGACATTATAATGGGCTTTTGCACTGTTATTATTTTTCCT
TTGGAATGTGAAGGTCTGAATGAGGGTTTTGATTTTGAATGTTTCAATGTTTTTGAGAAGCCTTGCTTACATTTTATGGTGTAGTCATTG
GAAATGGAAAAATGGCATTATATATATTATATATATAAATATATATTATACATACTCTCCTTACTTTATTTCAGTTACCATCCCCATAGA
ATTTGACAAGAATTGCTATGACTGAAAGGTTTTCGAGTCCTAATTAAAACTTTATTTATGGCAGTATTCATAATTAGCCTGAAATGCATT
CTGTAGGTAATCTCTGAGTTTCTGGAATATTTTCTTAGACTTTTTGGATGTGCAGCAGCTTACATGTCTGAAGTTACTTGAAGGCATCAC
TTTTAAGAAAGCTTACAGTTGGGCCCTGTACCATCCCAAGTCCTTTGTAGCTCCTCTTGAACATGTTTGCCATACTTTTAAAAGGGTAGT
TGAATAAATAGCATCACCATTCTTTGCTGTGGCACAGGTTATAAACTTAAGTGGAGTTTACCGGCAGCATCAAATGTTTCAGCTTTAAAA
AATAAAAGTAGGGTACAAGTTTAATGTTTAGTTCTAGAAATTTTGTGCAATATGTTCATAACGATGGCTGTGGTTGCCACAAAGTGCCTC
GTTTACCTTTAAATACTGTTAATGTGTCATGCATGCAGATGGAAGGGGTGGAACTGTGCACTAAAGTGGGGGCTTTAACTGTAGTATTTG
GCAGAGTTGCCTTCTACCTGCCAGTTCAAAAGTTCAACCTGTTTTCATATAGAATATATATACTAAAAAATTTCAGTCTGTTAAACAGCC
TTACTCTGATTCAGCCTCTTCAGATACTCTTGTGCTGTGCAGCAGTGGCTCTGTGTGTAAATGCTATGCACTGAGGATACACAAAAATAC
CAATATGATGTGTACAGGATAATGCCTCATCCCAATCAGATGTCCATTTGTTATTGTGTTTGTTAACAACCCTTTATCTCTTAGTGTTAT
AAACTCCACTTAAAACTGATTAAAGTCTCATTCTTGTCATTGTGTGGGTGTTTTATTAAATGAGAGTTTATAATTCAAATTGCTTAAGTC
CATTGAAGTTTTAATTAATGGGCAGCCAAATGTGAATACAAAGTTTTCAGTTTTTTTTTTTCCTGCTGTCCTTCAAAGCCTACTGTTTAA
AAAAAAAAAAAAAAAAAAACATGGCCTGAGAGTAGAGTATCTGTCTACTCATGTTTAATTAAGGAAAAACACTTATTTTTAGGGCTTTAG
TCATCACTTCATAAATTGTATAAGCACATTAAATAGCGTTCTAGTCCTGAAAAAGTCCAAGATTCTTAGAAAATTGTGCATATTTTTATT
ATGACAGATGTTTGAAGATAATTCCCCAGAATGGATTTGATACTTTAGATTTCAATTTTGTGGCTTTTGTCTATTATTCTGTACTCTGCC
ATCAGCATATGGAAAGCTTCATTTACTCATCATGACTTGTGCCATATAAAAATTGATATTTCGGAATAGTCTAAAGGACTTTTTGTACTT
GAATTTAATCATGTTGTTTCTAATATTCTTAAAAGCTTGAAGACTAAAGCATATCCTTTCAACAAAGCATAGTAAGGTAATAAGAAAGTG
TAGTTTGTACAAGTGTTAAAAAAATAAAGTAGACAATGTTACAGTGGGACTTATTATTTCAAGTTTACATTTTCTCCATGTAATTTTTTA
AAAAGTAAATGAAAAAATGTGCAATAATGTAAAATATGAAGTGTATGTGTACACACATTTTATTTTTCGGTATCTTGGGTATACGTATGG
TTGAAAACTATACTGGAGTCTAAAAGTATTCTAATTTATAAGAAGACATTTTGGTGATGTTTGAAAAATAGAAATGTGCTAGTTTTGTTT
TTATATCATGTCCTTTGTACGTTGTAATATGAGCTGGCTTGGTTCAGTAAATGCCATCACCATTTCCATTGAGAATTTAAAACTCACCAG
TGTTTAATATGCAGGCTTCCAAAGGCTTATGAAAAAAATCAAGACCCTTAAATCTAGTTAATTTGCTGCTAACATGAAACTCTTTGGTTC
TTTTATTTTTGCCAGATAATTAGACACACATCTAAAGCTTAGTCTTAAATGGCTTAAGTGTAGCTATTGATTAGTGCTGTTGCTAGTTCA
GAAAGAAATGTTTGTGAATGGAAACAAGAATATTCAGTCCAAACTGTTGTAAGGACAGTACCTGAAAACCAGGAAACAGGATAATGGAAA
AAGTCTTTTAAAGATGAAATGTTGGAGCCAACTTTCTTATAGAATTAATTGTATGTGGCTATAGAAAGCCTAATGATTGTTGCTTATTTT
TGAGAGCATATTATTCTTTTATGACCATAATCTTGCTGTTTTTCCATCTTCCAAAAGATCTTCCTTCTAATATGTATATCAGAATGTGGG
TAGCCAGTCAGACAAATTCATATTGGTTGGTAGCTTTAAAAAGTTTGTAATGTGAAGACAGGAAAGGACAAAATAGTTTGCTTTGGTGGT
AGTACTCTGGTTGTTAAGCTAGGTATTTTGAGACTACTTCCCCATCACAACAACAATAAAATAATCACTCATAATCCTATCACCTGGAGA
CATAGCCATCGTTAATATGTTAGTGACTATACAATCATGTTTTCTTCTGTATATCCATGTATATTCTTTAAAAATGAAATTTATACTGTA
CCTGATCTCAAAGCTTTTTAGCTTAGTATATCTGTCATGAATTTGTAGGATGTTCCATTGCATCAGAAAACGGACAGTGATTTGATTACT
TTCTAATGCCACAGATGCAGATTACATGTAGTTATTGAGAATCCTTTCGAATTCAGTGGCTTAATCATGAATGTCTAAATATTGTTGACA
TTAGGATGATACATGTAAATTAAAGTTACATTTGTTTAGCATAGACAAGCTTAACATTGTAGATGTTTCTCTTCAAAAATCATCTTAAAC
ATTTGCATTTGGAATTGTGTTAAATAGAATGTGTGAAACACTGTATTAGTAAACTTCATCACCTTTCTACTTCCTTATAGTTTGAACTTT
TCAGTTTTTGTAGTTCCCAAACAGTTGCTCAATTTAGAGCAAATTAATTTAACACCTGCCAAAAAAAGGCTGCTGTTGGCTTATCAGTTG
TCTTTAAATTCAAATGCTCATGTGACTTTTATCACATCAAAAAATATTTCATTAATGATTCACCTTTAGCTCTGAAAATTACCGCGTTTA
GTAATTATAGTGGGCTTATAAAAACATGCAACTCTTTTTGATAGTTATTTGAGAATTTTGGTGAAAAATATTTAGCTGAGGGCAGTATAG
AACTTATAAACCAATATATTGATATTTTTAAAACATTTTTACATATAAGTAAACTGCCATCTTTGAGCATAACTACATTTAAAAATAAAG
CTGCATATTTTTAAATCAAGTGTTTAACAAGAATTTATATTTTTTATTTTTTAAAATTAAAAATAATTTATATTTCCTCTGTTGCATGAG
GATTCTCATCTGTGCTTATAATGGTTAGAGATTTTATTTGTGTGGAATGAAGTGAGGCTTGTAGTCATGGTTCTAGTGTTTCAGTTTGCC
AAGTCTGTTTACTGCAGTGAAATTCATCAAATGTTTCAGTGTGGTTTTCTGTAGCCTATCATTTACTGGCTATTTTTTTATGTACACCTT
TAGGATTTTCTGCCTACTCTATCCAGTTGTCCAAATGATATCCTACATTTTACAAATGCCCTTTCAGTTTCTATTTTCTTTTTCCATTAA
ATTGCCCTCATGTCCTAATGTGCAGTTTGTAAGTGTGTGTGTGTGTGTCTGTGTGTGTGTGAATTTGATTTTCAAGAGTGCTAGACTTCC
AATTTGAGAGATTAAATAATTTAATTCAGGCAAACATTTTTCATTGGAATTTCACAGTTCATTGTAATGAAAATGTTAATCCTGGATGAC
CTTTGACATACAGTAATGAATCTTGGATATTAATGAATTTGTTAGTAGCATCTTGATGTGTGTTTTAATGAGTTATTTTCAAAGTTGTGC
ATTAAACCAAAGTTGGCATACTGGAAGTGTTTATATCAAGTTCCATTTGGCTACTGATGGACAAAAAATAGAAATGCCTTCCTATGGAGA

>80116_80116_1_SEC31A-PTEN_SEC31A_chr4_83799881_ENST00000355196_PTEN_chr10_89725042_ENST00000371953_length(amino acids)=195AA_BP=134
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSGVLI
AGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPE

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SEC31A-PTEN


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSEC31Achr4:83799881chr10:89725042ENST00000311785-426800_1113134.01107.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000326950-425800_1113134.01182.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000348405-425800_1113134.01182.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000355196-629800_1113134.01221.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000395310-427800_1113134.01221.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000432794-428800_1113134.01234.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000443462-326800_1113129.01201.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000448323-427800_1113134.01221.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000500777-323800_1113134.01068.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000508502-427800_1113134.01206.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000509142-426800_1113134.01107.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000513858-424800_1113134.01068.0PDCD6
HgeneSEC31Achr4:83799881chr10:89725042ENST00000311785-426161_471134.01107.0SEC13
HgeneSEC31Achr4:83799881chr10:89725042ENST00000326950-425161_471134.01182.0SEC13
HgeneSEC31Achr4:83799881chr10:89725042ENST00000348405-425161_471134.01182.0SEC13
HgeneSEC31Achr4:83799881chr10:89725042ENST00000355196-629161_471134.01221.0SEC13
HgeneSEC31Achr4:83799881chr10:89725042ENST00000395310-427161_471134.01221.0SEC13
HgeneSEC31Achr4:83799881chr10:89725042ENST00000432794-428161_471134.01234.0SEC13
HgeneSEC31Achr4:83799881chr10:89725042ENST00000443462-326161_471129.01201.0SEC13
HgeneSEC31Achr4:83799881chr10:89725042ENST00000448323-427161_471134.01221.0SEC13
HgeneSEC31Achr4:83799881chr10:89725042ENST00000500777-323161_471134.01068.0SEC13
HgeneSEC31Achr4:83799881chr10:89725042ENST00000508502-427161_471134.01206.0SEC13
HgeneSEC31Achr4:83799881chr10:89725042ENST00000509142-426161_471134.01107.0SEC13
HgeneSEC31Achr4:83799881chr10:89725042ENST00000513858-424161_471134.01068.0SEC13


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for SEC31A-PTEN


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for SEC31A-PTEN


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource