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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SECISBP2-RIF1 (FusionGDB2 ID:80189)

Fusion Gene Summary for SECISBP2-RIF1

check button Fusion gene summary
Fusion gene informationFusion gene name: SECISBP2-RIF1
Fusion gene ID: 80189
HgeneTgene
Gene symbol

SECISBP2

RIF1

Gene ID

79048

55791

Gene nameSECIS binding protein 2ligand dependent nuclear receptor interacting factor 1
SynonymsSBP2C1orf103|HBiX1|RIF1
Cytomap

9q22.2

1p13.3

Type of geneprotein-codingprotein-coding
Descriptionselenocysteine insertion sequence-binding protein 2Sec insertion sequence-binding protein 2ligand-dependent nuclear receptor-interacting factor 1HP1-binding protein enriched in inactive X chromosome protein 1receptor-interacting factor 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000339901, ENST00000375807, 
ENST00000534113, ENST00000470305, 
ENST00000433166, ENST00000457745, 
ENST00000243326, ENST00000428287, 
ENST00000430328, ENST00000444746, 
ENST00000453091, 
Fusion gene scores* DoF score12 X 8 X 7=6725 X 5 X 3=75
# samples 146
** MAII scorelog2(14/672*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/75*10)=-0.321928094887362
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SECISBP2 [Title/Abstract] AND RIF1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSECISBP2(91934712)-RIF1(152315324), # samples:1
Anticipated loss of major functional domain due to fusion event.SECISBP2-RIF1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SECISBP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RIF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1923SECISBP2chr9

91934712

+RIF1chr2

152315324

+


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Fusion Gene ORF analysis for SECISBP2-RIF1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000339901ENST00000433166SECISBP2chr9

91934712

+RIF1chr2

152315324

+
5CDS-intronENST00000339901ENST00000457745SECISBP2chr9

91934712

+RIF1chr2

152315324

+
5CDS-intronENST00000375807ENST00000433166SECISBP2chr9

91934712

+RIF1chr2

152315324

+
5CDS-intronENST00000375807ENST00000457745SECISBP2chr9

91934712

+RIF1chr2

152315324

+
5UTR-3CDSENST00000534113ENST00000243326SECISBP2chr9

91934712

+RIF1chr2

152315324

+
5UTR-3CDSENST00000534113ENST00000428287SECISBP2chr9

91934712

+RIF1chr2

152315324

+
5UTR-3CDSENST00000534113ENST00000430328SECISBP2chr9

91934712

+RIF1chr2

152315324

+
5UTR-3CDSENST00000534113ENST00000444746SECISBP2chr9

91934712

+RIF1chr2

152315324

+
5UTR-3CDSENST00000534113ENST00000453091SECISBP2chr9

91934712

+RIF1chr2

152315324

+
5UTR-intronENST00000534113ENST00000433166SECISBP2chr9

91934712

+RIF1chr2

152315324

+
5UTR-intronENST00000534113ENST00000457745SECISBP2chr9

91934712

+RIF1chr2

152315324

+
Frame-shiftENST00000339901ENST00000243326SECISBP2chr9

91934712

+RIF1chr2

152315324

+
Frame-shiftENST00000339901ENST00000428287SECISBP2chr9

91934712

+RIF1chr2

152315324

+
Frame-shiftENST00000339901ENST00000430328SECISBP2chr9

91934712

+RIF1chr2

152315324

+
Frame-shiftENST00000339901ENST00000444746SECISBP2chr9

91934712

+RIF1chr2

152315324

+
Frame-shiftENST00000339901ENST00000453091SECISBP2chr9

91934712

+RIF1chr2

152315324

+
In-frameENST00000375807ENST00000243326SECISBP2chr9

91934712

+RIF1chr2

152315324

+
In-frameENST00000375807ENST00000428287SECISBP2chr9

91934712

+RIF1chr2

152315324

+
In-frameENST00000375807ENST00000430328SECISBP2chr9

91934712

+RIF1chr2

152315324

+
In-frameENST00000375807ENST00000444746SECISBP2chr9

91934712

+RIF1chr2

152315324

+
In-frameENST00000375807ENST00000453091SECISBP2chr9

91934712

+RIF1chr2

152315324

+
intron-3CDSENST00000470305ENST00000243326SECISBP2chr9

91934712

+RIF1chr2

152315324

+
intron-3CDSENST00000470305ENST00000428287SECISBP2chr9

91934712

+RIF1chr2

152315324

+
intron-3CDSENST00000470305ENST00000430328SECISBP2chr9

91934712

+RIF1chr2

152315324

+
intron-3CDSENST00000470305ENST00000444746SECISBP2chr9

91934712

+RIF1chr2

152315324

+
intron-3CDSENST00000470305ENST00000453091SECISBP2chr9

91934712

+RIF1chr2

152315324

+
intron-intronENST00000470305ENST00000433166SECISBP2chr9

91934712

+RIF1chr2

152315324

+
intron-intronENST00000470305ENST00000457745SECISBP2chr9

91934712

+RIF1chr2

152315324

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000375807SECISBP2chr991934712+ENST00000444746RIF1chr2152315324+51342537148161581
ENST00000375807SECISBP2chr991934712+ENST00000453091RIF1chr2152315324+52902537147381555
ENST00000375807SECISBP2chr991934712+ENST00000428287RIF1chr2152315324+50562537147381555
ENST00000375807SECISBP2chr991934712+ENST00000243326RIF1chr2152315324+119182537148161581
ENST00000375807SECISBP2chr991934712+ENST00000430328RIF1chr2152315324+50562537147381555

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000375807ENST00000444746SECISBP2chr991934712+RIF1chr2152315324+9.14E-050.99990857
ENST00000375807ENST00000453091SECISBP2chr991934712+RIF1chr2152315324+0.0002267120.9997733
ENST00000375807ENST00000428287SECISBP2chr991934712+RIF1chr2152315324+0.0002718420.99972814
ENST00000375807ENST00000243326SECISBP2chr991934712+RIF1chr2152315324+2.24E-050.9999776
ENST00000375807ENST00000430328SECISBP2chr991934712+RIF1chr2152315324+0.0002718420.99972814

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Fusion Genomic Features for SECISBP2-RIF1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SECISBP2chr991934712+RIF1chr2152315324+0.000633520.99936646
SECISBP2chr991934712+RIF1chr2152315324+0.000633520.99936646

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SECISBP2-RIF1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:91934712/chr2:152315324)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSECISBP2chr9:91934712chr2:152315324ENST00000339901+217380_38728782.0Compositional biasNote=Poly-Lys
HgeneSECISBP2chr9:91934712chr2:152315324ENST00000375807+217380_38760855.0Compositional biasNote=Poly-Lys
HgeneSECISBP2chr9:91934712chr2:152315324ENST00000339901+217673_69428782.0RegionRNA-binding
HgeneSECISBP2chr9:91934712chr2:152315324ENST00000375807+217673_69460855.0RegionRNA-binding


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Fusion Gene Sequence for SECISBP2-RIF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80189_80189_1_SECISBP2-RIF1_SECISBP2_chr9_91934712_ENST00000375807_RIF1_chr2_152315324_ENST00000243326_length(transcript)=11918nt_BP=253nt
GCTTTGTCTGTCCGGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCATGGCGTCGGAGGGGCCGC
GGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGT
CCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAACCAGTACTAACACAAG
CCAAACAAAAATTTCTGCTCCTGTTGCCTGGTTTGGAAACTGTTGAAATGATGGAGGAATCCAGTGGACCATATTCTGATGGAACAGAAA
ATTCACAACTAAATGTGAAGATAAGTGGCATGGAGAGAAAATCAAATGGAAAAAGAGATTCATTTTTGGCACAAACAAAGAATAAAAAAG
AAAATATGAAACCAGCAGCCAAACTGAAACTTGAATCTTCGTCTTTAAAAGTAAAGGGTGAAATTCTTTTGGAAGAGGAAAAGTCTACTG
ACTTTGTGTTTATACCTCCAGAAGGAAAAGATGCAAAGGAAAGAATATTAACTGATCATCAAAAAGAAGTTCTCAAAACAAAGCGGTGTG
ATATTCCTGCCATGTATAATAATCTGGATGTTTCCCAAGATACCTTATTTACTCAGTATAGTCAGGAAGAGCCTATGGAAATTCCTACTT
TAACCAGAAAACCAAAGGAGGATTCTAAGATGATGATTACGGAGGAGCAAATGGACAGTGACATTGTCATTCCTCAAGATGTCACGGAAG
ACTGTGGTATGGCTGAACATCTTGAAAAGTCCTCCCTTTCGAATAATGAGTGTGGTTCTCTTGACAAAACCAGTCCAGAAATGTCAAACA
GTAATAATGATGAAAGAAAAAAAGCTTTAATTTCATCAAGGAAAACATCAACTGAATGTGCATCTAGTACAGAAAATTCTTTCGTTGTCA
GCAGTAGTTCAGTTTCTAATACCACTGTTGCTGGAACTCCCCCATACCCTACAAGTCGGAGGCAAACCTTTATTACTTTGGAGAAGTTTG
ATGGTTCAGAAAATAGACCTTTTAGTCCATCCCCCTTGAATAATATTTCATCAACTGTTACAGTGAAAAATAACCAGGAAACCATGATTA
AAACAGATTTTCTACCAAAAGCAAAGCAAAGAGAAGGGACTTTTTCAAAATCTGATTCTGAAAAAATAGTGAATGGAACTAAGAGATCAA
GCCGGAGAGCTGGTAAAGCTGAACAAACAGGGAATAAAAGGTCTAAGCCCTTAATGAGATCTGAGCCGGAGAAAAATACTGAGGAATCTG
TTGAAGGCATTGTAGTCTTAGAAAATAACCCACCTGGTTTGCTTAATCAAACAGAATGTGTGTCAGATAATCAGGTTCATCTTTCTGAAT
CTACAATGGAGCATGACAATACAAAGCTTAAAGCAGCAACAGTGGAAAATGCTGTATTATTGGAAACTAATACTGTAGAGGAGAAAAATG
TAGAAATTAATTTGGAATCCAAAGAGAATACACCCCCAGTAGTAATATCAGCAGATCAAATGGTAAATGAGGATAGTCAGGTTCAGATAA
CTCCAAATCAGAAAACCCTTAGACGGTCTTCAAGGCGACGTTCAGAAGTAGTAGAGTCTACCACTGAAAGCCAAGATAAGGAAAATAGTC
ATCAAAAAAAGGAACGACGTAAGGAAGAAGAAAAACCTCTTCAGAAGAGTCCATTGCATATAAAAGATGATGTGTTACCTAAACAAAAAC
TGATTGCTGAACAAACTCTACAGGAGAATTTAATTGAGAAAGGAAGTAATTTACATGAGAAGACTCTTGGGGAAACTAGTGCTAATGCAG
AAACTGAACAAAATAAAAAAAAGGCAGACCCTGAGAACATTAAGTCTGAGGGGGATGGTACCCAGGACATTGTAGATAAGTCCTCTGAGA
AACTAGTCAGAGGCCGAACACGGTATCAAACTAGAAGAGCATCTCAGGGTTTGCTTTCCAGCATTGAAAACTCAGAATCTGATAGTTCGG
AGGCAAAAGAAGAAGGTTCTAGGAAGAAGAGATCTGGAAAATGGAAAAACAAAAGCAATGAAAGTGTTGACATTCAAGATCAAGAAGAGA
AAGTGGTGAAACAGGAATGTATAAAAGCTGAAAATCAGTCACATGATTATAAAGCAACTTCTGAAGAAGATGTAAGCATAAAATCTCCGA
TTTGCGAAAAACAAGATGAAAGTAATACTGTAATATGTCAGGATTCTACAGTAACTTCAGATTTGTTGCAAGTTCCTGATGATTTACCAA
ATGTGTGTGAGGAAAAAAATGAAACTAGCAAATATGCAGAATATTCCTTTACAAGTCTACCTGTGCCAGAATCAAATCTAAGGACTAGAA
ATGCCATTAAGAGATTACATAAGCGAGACTCTTTTGATAATTGTAGTTTGGGAGAATCCTCAAAAATAGGGATATCAGATATTTCTTCGC
TTTCAGAAAAAACTTTTCAAACACTTGAATGCCAACACAAGAGAAGTAGGAGGGTGAGGAGATCTAAAGGTTGTGATTGCTGTGGGGAAA
AATCACAACCTCAGGAAAAGTCACTCATTGGGTTAAAGAATACAGAAAATAATGACGTAGAGATTAGTGAAACAAAAAAGGCAGATGTGC
AAGCACCTGTAAGCCCATCAGAAACTTCTCAAGCTAATCCATATTCTGAAGGACAATTTTTAGATGAACATCATAGTGTGAATTTTCATT
TGGGTCTCAAAGAGGATAATGATACTATTAATGATTCATTAATTGTTTCTGAAACCAAATCAAAAGAAAACACTATGCAAGAATCTCTTC
CTTCTGGAATAGTAAACTTTAGAGAGGAAATTTGTGATATGGATTCTAGTGAAGCAATGTCTCTTGAAAGCCAGGAGTCACCTAATGAAA
ATTTTAAAACTGTTGGCCCGTGTTTAGGAGACTCGAAAAATGTTTCACAGGAATCTTTGGAGACAAAAGAAGAAAAACCAGAAGAAACCC
CAAAAATGGAACTGAGTCTAGAGAATGTTACTGTTGAAGGAAATGCATGTAAAGTAACAGAATCCAATCTAGAGAAAGCAAAAACTATGG
AATTGAATGTAGGAAATGAAGCTAGCTTTCATGGACAAGAGAGAACCAAAACTGGTATTTCTGAAGAAGCAGCAATAGAAGAAAATAAAA
GAAATGATGACTCTGAAGCAGACACAGCTAAACTGAATGCCAAAGAAGTAGCAACTGAGGAATTTAATTCAGATATTAGTCTTTCTGATA
ATACTACACCTGTAAAATTGAATGCTCAAACTGAGATTTCTGAACAAACAGCAGCTGGGGAACTAGATGGAGGAAATGATGTATCTGATC
TACACTCATCTGAAGAAACGAATACCAAAATGAAAAATAATGAAGAAATGATGATCGGCGAGGCAATGGCTGAAACTGGCCATGATGGTG
AAACAGAGAATGAGGGCATAACTACCAAAACCTCAAAGCCTGATGAAGCTGAAACAAACATGTTGACTGCAGAAATGGACAACTTTGTTT
GTGACACAGTTGAAATGAGCACTGAAGAAGGAATCATTGACGCTAATAAAACTGAAACAAATACTGAGTATAGTAAATCTGAAGAAAAAT
TAGATAACAATCAAATGGTAATGGAAAGTGATATTTTACAGGAAGATCACCATACTTCACAGAAAGTGGAGGAACCATCACAGTGTCTGG
CATCTGGAACAGCTATCTCTGAGCTAATAATAGAAGACAATAATGCATCTCCTCAAAAACTAAGGGAACTTGATCCTTCACTTGTGTCAG
CAAATGACAGTCCTAGTGGCATGCAGACACGCTGTGTCTGGTCTCCTTTGGCTTCTCCGTCTACGAGCATTTTAAAGAGAGGACTAAAAA
GATCCCAAGAAGATGAAATCTCATCACCTGTTAATAAGGTTCGCCGTGTCTCCTTTGCAGATCCAATATACCAAGCAGGATTGGCAGATG
ACATTGATAGACGGTGCTCTATTGTTAGGTCCCATTCTTCCAATAGTTCTCCCATAGGAAAAAGTGTTAAAACTTCTCCTACTACACAAT
CTAAGCATAATACCACTTCAGCCAAAGGATTTCTGTCCCCAGGATCACGTAGCCCTAAATTTAAGAGCTCAAAGAAGTGTTTAATTTCAG
AAATGGCCAAAGAATCCATACCATGCCCAACAGAAAGTGTTTACCCACCATTGGTGAACTGTGTGGCACCAGTTGACATCATTTTACCTC
AGATTACATCAAACATGTGGGCAAGAGGCCTGGGACAACTCATTAGAGCTAAGAATATAAAAACTATTGGTGATTTGAGTACTCTTACAG
CATCTGAAATAAAAACTCTTCCTATCCGTTCTCCAAAAGTGTCCAATGTAAAAAAGGCTCTCAGAATATATCATGAGCAGCAGGTGAAGA
CTCGTGGACTAGAAGAGATTCCAGTTTTTGATATTTCTGAAAAAACAGTAAATGGAATAGAAAATAAATCTTTGTCACCTGATGAAGAAA
GACTTGTCTCAGATATAATTGATCCTGTTGCTTTAGAAATTCCATTATCCAAAAACCTTCTGGCACAGATTAGTGCTCTTGCTCTTCAGC
TGGATTCAGAAGATCTTCATAATTATTCAGGAAGCCAACTATTTGAAATGCACGAGAAACTAAGTTGTATGGCAAACTCTGTAATAAAAA
ATCTACAGTCACGTTGGAGATCACCATCCCATGAAAATTCTATTTAGTATTTTCAGAGAAAATTGAAGGTTTTTTTAAACATCACTGGAT
TTCTTGATTGAGGAAACAAGTTCTGAAATAATAGCACAATTTCAAAGAAGAGACTCTTTGCAAAGTTGATAACATTTCAAACCCTGAAGG
ACAGTGACTTATTATGTAAGTTCAATTTTGTAAGTTCATTATGTAAGATCCTTTTTTTTTTCATAATATGTATTCTTGGCTGCTATGCGT
GGTTTTTCAGGAAATTTAATTATCTTACTGAGATGTGAAAGCAAAACTAGTAACAGAACTTACATTTTATTTCATGCTTTCTTAAACCCG
TGCATATTCTGGTGAAACATGTAAAATACTTTAAGTAAAATTGAACATTTTTATTTGAATTTTTGCTGAACTGATAAAGGTGTTTATATT
TTTGTTTGTTGGTTTGTTTAATTCATGTTTGTTGGGACTGAGGTTTAGGAAGTTTGTTACTGGTTAAAAACCTCAAATGAAATGCGAAAG
AATTTGAATTTTTCCTGCATATGTCAACTTTGGACAGCTTTCAAGAAAAATGAGAAAAGTTTCAACTTCTGGCGGTTAAAATATTAATGC
AGAATTTACTAAGATTTTATTCATTTGCATTAGCAAATATTCATGCAGCAGCAGTTGACTGAAAATTTATTCTTATGAGACGTATAGTAT
TCATTTTTAAATGCATGATTGTACATTATGTATAGACGACAATGTTTTTAATTTATAAATTTCATTCTTTGTTAATTGCATGGGTTTTTC
TGCAGCTTATTGTGAATACCTTGGTTCTGTTCAATAGAAACATTTTGTATATATTAAATACTGAAATATCAGTATCGACGGTGGAAGTGC
TTCATGGGCTTGCTGCACATATTTGTAGGATACTGTATCTGCAAATGCAACAACAAATAGTTTTGTACTTGGTTAACAGTCTTAGTTAAA
ACATGAGTTTATTTTCTAAAAGTATCCAGAATAAGTAAAATTATAGAAATAAGAAAATGTTACACAACTTTGCTGTTCATACCCTTACCT
TCTTACTACTTTTGGTTTGGAGGAGGGTATCACCACTAGAAAGTGTGCCTCCTTAAGATTTCTTAAAGGAAAGTTAGTTTCAGTATTTCA
CAGCAAGTTGGACTACAAAATCTAGAGTTGATCTGCTTTTTAAACCTTCATTTAAAAGCAAACTTGGAAGAAATTTGAAACTGATGTTTT
TAATATATGTCTGTGTTGCCTAGGTTTTCTTTTTTTAAAGAGGTATGTAATTAAAACCTTTGTAAAATTTGCCAACTAATATTAGTGCCT
GACTTCCCATATTTGTTTCATCTTTTTAACTGACAGTATATCTCACTTCTTCTTTGAATAGAATGAGTGAGTGATCTCAGTTTTCACATT
TTATTCAGAAGCTAATCCCTACTTAGCAAGGCACACATTCTACAGCAAGTCATAGAAAGTTTAATCCTTGTGCCTCCTTAGCTCTCGTAT
ATTCAGGGATCTCTATAAAAGTTGGTGTCTTTTTTCATCATCATAAATTCATCATAATCACAGATATTTTTGGGTCTAAGATATTCATAT
ACCAAGGATGGTTTTGTAAAGAATTCTGGGATCATTGAATTAAGGATTGTGGCTTGAAGTAACTAAAGAAAAATACTAATTTCCTTAAAA
GGAATTATAATTATGATTTACATTTTACATCATTAATTTCCCAAATTATATTTAACCGTAAGGAGGTGCACATGAGTTTTTAGCAAACAG
GTATGAATAAGCAGCTATGTATATGTGTTTGGGGCAGAGGGGAGCAGATTACTTTAACACACTTCAGAATTAAAATCAGTTCGTTTCATG
ACTCTGTGCCTTAACGTTTGTGTGAACTAAACTTGCTGATTGAATGAAATTCTTGGGAAGCCGAACAGTAATAGCAGAAAATGTGACCAA
ATGAGTATCATGTACTTAAATCACTGAATTTTATATAAGCACAAGTATTAATTTTAAAAACATTATAGTTTAATAAAGCTGCATTTAAAA
ATATTTGGGAGCAAAGACAAGCATGCTAAATCTTCATTTTGCTATGGCTATAAGCATATATTTTTGGCAACTTATTTGCAATATTCTTGC
CTTAAAGTTTCCTGCAAATTTCCCCCTTAGTAATTCCCGAATAGCAAAACATTAATATTCCATGATTAGCTCTACTGTGTTGTCTCACTA
TTAAAATGGAATTCGTTTTTTCAGATCTTTTCTAATGGTTAATAAAACAAATGTCAGATCATAATAACACTCAAATGTGTCTTAATTGTC
TTATGCATATTTAAGAAGAAAAAACTAGTGGCATACAGGATTGTCATGTAGTATCTTTTTTTTTTTTTGAGACACAGTCTTGCTCTGTTG
CCTATGCTGGAGTGCAATGGTGCGATCTCGGTTCACTGCAAGCTCTGCCTCCCAGGTTTACACCATTCTCCTGCCTCAGCCTCCCAAGTA
GCTGGGACTACAGGTGCCCGCCACCATGCCCGGCTAATTTTTTATATTTTTAGTAGAGAAGGGGTTCACTGTGTTAGCCAGGATGGTCTT
GATCTGACCTCGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCCCACCTGGCCATTTTCTTTTTTTTT
TGAGGTGGAGTTTTCGCCCTTGCTGCCCAGGCTGGAGTGCAGTGGTACGATCTCAGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCGA
TTCTCCTGCCTCAGCCTCCCAAATAGCTGGGATTACAGGTGCCTGCCACCACCACTGGTTAATTTTTGTATTTTTAGTAGATACGGGGTT
TCACCATGTCAGCCAGGCTGGTCTCAAACTTCTGACCTCAGATATCCACCTGCCTCAGCCTCCTAAAATGGTGGCATTACAGGCGTGAGC
CACCGCTCCTGGCCCATCATTTCCATATCTATGAAATCTATTTTGGATTTTAGAGTGGATTTAAATTTTCAATATTTCAGTGACCTCATT
GTTAAAGCTGCTTTGCCACTTGTACAAGTTTGAAAACCATTGTTGAATCATATGGAGCTTTACTCTAATTCCAAATAGTTAAAGGATGAA
TCAGGTTAAATAATGCTGTTGGATAATACAGGCAAAAACAGGATTTAAACCCGCACATTAAAAGCATGACTGAAGGCCCGGCAGGTGGAT
CACTTTGGCCCAGGAGTTCAAAACTGACCTGAACAATGTGGCGAAATCCTGTCTCTACTAAAAATACAAAAACCAGCCAGGCATGTTGGC
GCATACTTGTAATCTCAGCTACTCAGGAGGCTGAGACATGAGAATTGCTTGAACCTTTTAGGCGGAGGTTGCAGTGAGCCGAGATCATGC
CATTGCGCGACAGAGCAAGTCTCTGTCTCGCAAAAAAAAAAAAAAAGTTTAATTCTAACATTGCCCATGGATTTTTTTTTTTCTGTACAG
CTTGAAGATAAGATAGTTAAAGACTCTGTTACAATTTAAACATCATAAAAATGTGAAGAGTAAGTGGTGAGGCAAGAAACAAAATTGGGG
GAAATGGTGGGGATCGTGAATATATAAGTGAAGTTTTATTTTTTTAAGGTGTAAAGGAGTGAGAATAGAGTAATTGCTTTTTAAAAAGAA
AGTATAAATGGGTTAATTTTTTTCTTCCAACTTTGACTTTAATTCAGTAAGAAAGGCCTAGGTTTCATCTCATATTCTTCATAATTGATT
TTCAAGAAGTTAATTTGTCATTCAGCCTAGGAGGCTATAAAACAGCAGTTAGTTGGCATTATTAGACTAAAACTTGGGTGGGGGGAGGAG
ACTGTTTCCTCATTGCTGCAACCCATGGTCTATCCTATTCCTAAGCCATTAGAAAGACCTTGTACTTTGTATAGAAACATTAGAGTGAGG
TTTTGATTTTTAACATAGTACTCTCAAACTTTGATGTGCATATGAACAAGTGGATTCTGATTCAGTAGATCTGCATTGGGCCCCGTGAGT
CTTTTTAAACACAGTCCCAGGTGATTCATGCAGATGCCTGTGAACTGCGCTGGTAGATGGGCCTAAGAGGCTTCAGGCTGTGTTTTAGGT
TTTGGTAAGCCAGGCAGATTCAAGTCCTTTTATAACTGTCAATTTTGTGAATTGGGGATGCAGACTGGTTTTGAAGGCTTAAAGTTCAAA
AATTATAAGAAAGTTAAGAATTTTGCTTAAGAGCCTTTTAAAAATATGGACGATTTATTTTTTAAGTAGGCAGACTAAGAATTTCAAGTT
ATAAAGAATCTTATTGATAAGGCAAAGTAGACAAAGTATTTTCTCATGAGTATTTGTGGGTTATGTTTTTGTTAATATAAAAGTTGATTT
CTAAGTATTAGAATATATTTAGTCTCTAAATAAATCTTGCCTTCTATTATGGATCATCGTTATTAATAAACATGGAAAATCAACACTACC
CCTAATATTAATCTGGCAGTTAAATTTAGTAGTGCTATAATGAATAAGTCAGTCTAGCAGATATGCCCTGTCATTATACTGCGGACCTCT
GGTCACTTAATTTTCTGTTATATTATGTGGTTGAAAATTCCTGTTTCATCGTAAAGTGAAATTTGAAAGATGGAGTTGAATAATATGATT
CTCGAAAAGTGAGTTTTTCTTGGAATTCTGTTAAGGTGTTAGATTTTCCTCACATATTTAAATAATCTGTAAGAACTACCCTGAAAGCAC
TAAGGAAAATGTAGCCGAAAGTTAAGTAATAGGTTTTAAAAATTTATCAAAATTTATTGATAGTTTGATCTGTAAAACAAATTGGGTTTC
GTGCTTTCTGATGTCCAGTTAATAAGTATATTATGTGCCAGGCTTTACATATTGCTCTTTGCAAGTAGCCGTTAAAGTGTAAGTCATTGA
AGTTTGAAGATCTATAAATATTTAATATAGTAGTCTAAACAGTTGTGAGAATTTACTCAGTTCTGAAATAGAATGTTAAATTTTCCGATG
TGGTCCTAATCATTTTTTTCTTTACATACTAAGCCTTCCTTTCTCCAAAGAACAGTTAAAACCAAATGTGTTATGGTAAGCTGTAAATAC
CGTTGGAATAAAAGATAACCGTTCATCTTACCTAAAAAATTGAAGACAATATTTTCCATTGTTGATGTCACAAGTAAGAAAAAAACTCTA
ACTTTTGTACTCTACTTGTAGCAGAGGGAATATTTTTGGCCACAGTGTGCCAATTTATAATTGTAGATAAAGCTGAATTTACTGGGCAGC
AAGCTTATATGCTGATAGAAGTTGATGCACTGAGAAGTGATGAGTTGAAGAGAATGGAAAAGGCAGATTGAGCTGGAATTTTAATGCATA
GTACATTTAGTAGAGAGACAAGCTGTCCTATATACTCCTGTATACTTCAGAAATAGCTGATAGCCTATAGTCTCTGAGAGCTATTCTGTA
CATAGCACAGTATTATAATTGATGTTCATAAATACCCTGAGAGATTATGTTAAAATACATTATTAATACTCCCACAAAAGCAGTAAGTTA
ATAAGTATTTCCAACAAAAGGCAGCTTTGTTTCTTAAACGGATAAACAACATATAACTAGGAAGATCATCTTCAAAATAAAGTGTCATGG
AACTGAAAATAGAGTATAGTCTAACAATTATTTTGATACACTATTGAATAGCTAACAAGTGTCTAAAGAATTTTTTATTTTTATAGAATA
GGAAGTTTCTAAAAGAAAACAATTAAGAGCAAAATTGGTTTTGAGTATAGAAACTGAAGGATGGCAGTCTTAACTCCTAAGTTTTTTACA
GAGCACAGATTGGTAAACTAGCATGCCACCTGTTTTTTGTACTATCTGTGAGCTGAGACTGGTTTTTACATTTTTTAATGGTGAAAAAAG
TCAAAAGAAGGACATTTTGTGACACATGAAAACATATTAAATTAAAATTTCAGTATCCAGAAATAAAGTTTTATTGGAACAGCTGTGCTT
ATTGTCTTTAGCTGCTTTCCTGGTACAGTGGCTGAGTTTAGTAGTATAGCAGAGTCTGTATGGCTTCCAACAGTCAAAATACTGCCTGGC
CTTTTAAAGAGTTTGTCAATCCCTTTTATGGAGGAAGGTTTTGCTCATGCATGGCATGTTAGTCAATTTAGTTATTTGCTTCTAGCTGGC
AGAATGTGGTCTTGATTACTTAATTTCTGTTACCCCTGTGTTTTCCAGAATGGCTTCTCCTGATTTTACTTACGTGTTTTACTATTGCTC
AAATTACAGATACTAGGAAACACTACTACTTTATAAGTACACTTCTTTTTCCTACTTAAACTCTCAAACTACAGTTACGTATTTGCCATG
ATGTTAAGGGACCTTGATGGTCTGTGAATTATCAGTTGCTTTCTGCACTACCTCCTGTAGATAGACCTGACTGATAGCACTTACAAAAAG
ACTGATAGATGCCAAATCAGTCATTTATTAACCCTCTAATATTGTTGTCCCGATCATTTGGTAAACGCTAAGAGAGCTTAGTTTTACATT
CACAAAGTATTTGTATTTGATAAGTCTTAAAAATGATTTAAGTTGAAGCCTAACAGAAGTACTTGTTCATTCCTCAGTTACCTGCAAATA
ATGGAAATAATGGTGCAGTCAGTTTTATTTGATTGTGTAATGCTTTATACTAGGGGTCTCAAACCCCTGGGTGGCATTAGATTCTTACAG
GAGCGTGAACCCTATTGTGAACTGCACATGCAAGAGATCTAGGTTGTGCGCTCATTATGAGAATCTAATACCCGATGATCTGAGGTGGAA
CAGTCTCATCCTGAAACCATCTACCCCAACACCTGTGTCTGTGGAAATTGTCTCCACGAAACCGGTCCCTGTTGAAAAAAGGTTAGGGGA
CCACTGCTTTATACAGTGTTTGAAGTAGGCACACTTACAGTTACTATTTCTGGTTCTTTATGACTGTTGAGGGGGGGCAGAATTCTATGT
TTGATTCACAGTAAAACTTTTCATGAATCATTGAGGGTTAACTGTTATCACTTGCCAATGGAAACTGGATATTGAAACATTTTTTTAAGA

>80189_80189_1_SECISBP2-RIF1_SECISBP2_chr9_91934712_ENST00000375807_RIF1_chr2_152315324_ENST00000243326_length(amino acids)=1581AA_BP=61
MASEGPREPESEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTEPVLTQAKQKFLLLLPGLETVEMMEESSGP
YSDGTENSQLNVKISGMERKSNGKRDSFLAQTKNKKENMKPAAKLKLESSSLKVKGEILLEEEKSTDFVFIPPEGKDAKERILTDHQKEV
LKTKRCDIPAMYNNLDVSQDTLFTQYSQEEPMEIPTLTRKPKEDSKMMITEEQMDSDIVIPQDVTEDCGMAEHLEKSSLSNNECGSLDKT
SPEMSNSNNDERKKALISSRKTSTECASSTENSFVVSSSSVSNTTVAGTPPYPTSRRQTFITLEKFDGSENRPFSPSPLNNISSTVTVKN
NQETMIKTDFLPKAKQREGTFSKSDSEKIVNGTKRSSRRAGKAEQTGNKRSKPLMRSEPEKNTEESVEGIVVLENNPPGLLNQTECVSDN
QVHLSESTMEHDNTKLKAATVENAVLLETNTVEEKNVEINLESKENTPPVVISADQMVNEDSQVQITPNQKTLRRSSRRRSEVVESTTES
QDKENSHQKKERRKEEEKPLQKSPLHIKDDVLPKQKLIAEQTLQENLIEKGSNLHEKTLGETSANAETEQNKKKADPENIKSEGDGTQDI
VDKSSEKLVRGRTRYQTRRASQGLLSSIENSESDSSEAKEEGSRKKRSGKWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEED
VSIKSPICEKQDESNTVICQDSTVTSDLLQVPDDLPNVCEEKNETSKYAEYSFTSLPVPESNLRTRNAIKRLHKRDSFDNCSLGESSKIG
ISDISSLSEKTFQTLECQHKRSRRVRRSKGCDCCGEKSQPQEKSLIGLKNTENNDVEISETKKADVQAPVSPSETSQANPYSEGQFLDEH
HSVNFHLGLKEDNDTINDSLIVSETKSKENTMQESLPSGIVNFREEICDMDSSEAMSLESQESPNENFKTVGPCLGDSKNVSQESLETKE
EKPEETPKMELSLENVTVEGNACKVTESNLEKAKTMELNVGNEASFHGQERTKTGISEEAAIEENKRNDDSEADTAKLNAKEVATEEFNS
DISLSDNTTPVKLNAQTEISEQTAAGELDGGNDVSDLHSSEETNTKMKNNEEMMIGEAMAETGHDGETENEGITTKTSKPDEAETNMLTA
EMDNFVCDTVEMSTEEGIIDANKTETNTEYSKSEEKLDNNQMVMESDILQEDHHTSQKVEEPSQCLASGTAISELIIEDNNASPQKLREL
DPSLVSANDSPSGMQTRCVWSPLASPSTSILKRGLKRSQEDEISSPVNKVRRVSFADPIYQAGLADDIDRRCSIVRSHSSNSSPIGKSVK
TSPTTQSKHNTTSAKGFLSPGSRSPKFKSSKKCLISEMAKESIPCPTESVYPPLVNCVAPVDIILPQITSNMWARGLGQLIRAKNIKTIG
DLSTLTASEIKTLPIRSPKVSNVKKALRIYHEQQVKTRGLEEIPVFDISEKTVNGIENKSLSPDEERLVSDIIDPVALEIPLSKNLLAQI

--------------------------------------------------------------
>80189_80189_2_SECISBP2-RIF1_SECISBP2_chr9_91934712_ENST00000375807_RIF1_chr2_152315324_ENST00000428287_length(transcript)=5056nt_BP=253nt
GCTTTGTCTGTCCGGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCATGGCGTCGGAGGGGCCGC
GGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGT
CCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAACCAGTACTAACACAAG
CCAAACAAAAATTTCTGCTCCTGTTGCCTGGTTTGGAAACTGTTGAAATGATGGAGGAATCCAGTGGACCATATTCTGATGGAACAGAAA
ATTCACAACTAAATGTGAAGATAAGTGGCATGGAGAGAAAATCAAATGGAAAAAGAGATTCATTTTTGGCACAAACAAAGAATAAAAAAG
AAAATATGAAACCAGCAGCCAAACTGAAACTTGAATCTTCGTCTTTAAAAGTAAAGGGTGAAATTCTTTTGGAAGAGGAAAAGTCTACTG
ACTTTGTGTTTATACCTCCAGAAGGAAAAGATGCAAAGGAAAGAATATTAACTGATCATCAAAAAGAAGTTCTCAAAACAAAGCGGTGTG
ATATTCCTGCCATGTATAATAATCTGGATGTTTCCCAAGATACCTTATTTACTCAGTATAGTCAGGAAGAGCCTATGGAAATTCCTACTT
TAACCAGAAAACCAAAGGAGGATTCTAAGATGATGATTACGGAGGAGCAAATGGACAGTGACATTGTCATTCCTCAAGATGTCACGGAAG
ACTGTGGTATGGCTGAACATCTTGAAAAGTCCTCCCTTTCGAATAATGAGTGTGGTTCTCTTGACAAAACCAGTCCAGAAATGTCAAACA
GTAATAATGATGAAAGAAAAAAAGCTTTAATTTCATCAAGGAAAACATCAACTGAATGTGCATCTAGTACAGAAAATTCTTTCGTTGTCA
GCAGTAGTTCAGTTTCTAATACCACTGTTGCTGGAACTCCCCCATACCCTACAAGTCGGAGGCAAACCTTTATTACTTTGGAGAAGTTTG
ATGGTTCAGAAAATAGACCTTTTAGTCCATCCCCCTTGAATAATATTTCATCAACTGTTACAGTGAAAAATAACCAGGAAACCATGATTA
AAACAGATTTTCTACCAAAAGCAAAGCAAAGAGAAGGGACTTTTTCAAAATCTGATTCTGAAAAAATAGTGAATGGAACTAAGAGATCAA
GCCGGAGAGCTGGTAAAGCTGAACAAACAGGGAATAAAAGGTCTAAGCCCTTAATGAGATCTGAGCCGGAGAAAAATACTGAGGAATCTG
TTGAAGGCATTGTAGTCTTAGAAAATAACCCACCTGGTTTGCTTAATCAAACAGAATGTGTGTCAGATAATCAGGTTCATCTTTCTGAAT
CTACAATGGAGCATGACAATACAAAGCTTAAAGCAGCAACAGTGGAAAATGCTGTATTATTGGAAACTAATACTGTAGAGGAGAAAAATG
TAGAAATTAATTTGGAATCCAAAGAGAATACACCCCCAGTAGTAATATCAGCAGATCAAATGGTAAATGAGGATAGTCAGGTTCAGATAA
CTCCAAATCAGAAAACCCTTAGACGGTCTTCAAGGCGACGTTCAGAAGTAGTAGAGTCTACCACTGAAAGCCAAGATAAGGAAAATAGTC
ATCAAAAAAAGGAACGACGTAAGGAAGAAGAAAAACCTCTTCAGAAGAGTCCATTGCATATAAAAGATGATGTGTTACCTAAACAAAAAC
TGATTGCTGAACAAACTCTACAGGAGAATTTAATTGAGAAAGGAAGTAATTTACATGAGAAGACTCTTGGGGAAACTAGTGCTAATGCAG
AAACTGAACAAAATAAAAAAAAGGCAGACCCTGAGAACATTAAGTCTGAGGGGGATGGTACCCAGGACATTGTAGATAAGTCCTCTGAGA
AACTAGTCAGAGGCCGAACACGGTATCAAACTAGAAGAGCATCTCAGGGTTTGCTTTCCAGCATTGAAAACTCAGAATCTGATAGTTCGG
AGGCAAAAGAAGAAGGTTCTAGGAAGAAGAGATCTGGAAAATGGAAAAACAAAAGCAATGAAAGTGTTGACATTCAAGATCAAGAAGAGA
AAGTGGTGAAACAGGAATGTATAAAAGCTGAAAATCAGTCACATGATTATAAAGCAACTTCTGAAGAAGATGTAAGCATAAAATCTCCGA
TTTGCGAAAAACAAGATGAAAGTAATACTGTAATATGTCAGGATTCTACAGTAACTTCAGATTTGTTGCAAGTTCCTGATGATTTACCAA
ATGTGTGTGAGGAAAAAAATGAAACTAGCAAATATGCAGAATATTCCTTTACAAGTCTACCTGTGCCAGAATCAAATCTAAGGACTAGAA
ATGCCATTAAGAGATTACATAAGCGAGACTCTTTTGATAATTGTAGTTTGGGAGAATCCTCAAAAATAGGGATATCAGATATTTCTTCGC
TTTCAGAAAAAACTTTTCAAACACTTGAATGCCAACACAAGAGAAGTAGGAGGGTGAGGAGATCTAAAGGTTGTGATTGCTGTGGGGAAA
AATCACAACCTCAGGAAAAGTCACTCATTGGGTTAAAGAATACAGAAAATAATGACGTAGAGATTAGTGAAACAAAAAAGGCAGATGTGC
AAGCACCTGTAAGCCCATCAGAAACTTCTCAAGCTAATCCATATTCTGAAGGACAATTTTTAGATGAACATCATAGTGTGAATTTTCATT
TGGGTCTCAAAGAGGATAATGATACTATTAATGATTCATTAATTGTTTCTGAAACCAAATCAAAAGAAAACACTATGCAAGAATCTCTTC
CTTCTGGAATAGTAAACTTTAGAGAGGAAATTTGTGATATGGATTCTAGTGAAGCAATGTCTCTTGAAAGCCAGGAGTCACCTAATGAAA
ATTTTAAAACTGTTGGCCCGTGTTTAGGAGACTCGAAAAATGTTTCACAGGAATCTTTGGAGACAAAAGAAGAAAAACCAGAAGAAACCC
CAAAAATGGAACTGAGTCTAGAGAATGTTACTGTTGAAGGAAATGCATGTAAAGTAACAGAATCCAATCTAGAGAAAGCAAAAACTATGG
AATTGAATGTAGGAAATGAAGCTAGCTTTCATGGACAAGAGAGAACCAAAACTGGTATTTCTGAAGAAGCAGCAATAGAAGAAAATAAAA
GAAATGATGACTCTGAAGCAGACACAGCTAAACTGAATGCCAAAGAAGTAGCAACTGAGGAATTTAATTCAGATATTAGTCTTTCTGATA
ATACTACACCTGTAAAATTGAATGCTCAAACTGAGATTTCTGAACAAACAGCAGCTGGGGAACTAGATGGAGGAAATGATGTATCTGATC
TACACTCATCTGAAGAAACGAATACCAAAATGAAAAATAATGAAGAAATGATGATCGGCGAGGCAATGGCTGAAACTGGCCATGATGGTG
AAACAGAGAATGAGGGCATAACTACCAAAACCTCAAAGCCTGATGAAGCTGAAACAAACATGTTGACTGCAGAAATGGACAACTTTGTTT
GTGACACAGTTGAAATGAGCACTGAAGAAGGAATCATTGACGCTAATAAAACTGAAACAAATACTGAGTATAGTAAATCTGAAGAAAAAT
TAGATAACAATCAAATGGTAATGGAAAGTGATATTTTACAGGAAGATCACCATACTTCACAGAAAGTGGAGGAACCATCACAGTGTCTGG
CATCTGGAACAGCTATCTCTGAGCTAATAATAGAAGACAATAATGCATCTCCTCAAAAACTAAGGGAACTTGATCCTTCACTTGTGTCAG
CAAATGACAGTCCTAGTGGCATGCAGACACGCTGTGTCTGGTCTCCTTTGGCTTCTCCGTCTACGAGCATTTTAAAGAGAGGACTAAAAA
GATCCCAAGAAGATGAAATCTCATCACCTGTTAATAAGGTTCGCCGTGTCTCCTTTGCAGATCCAATATACCAAGCAGGATTGGCAGATG
ACATTGATAGACGGTGCTCTATTGTTAGGTCCCATTCTTCCAATAGTTCTCCCATAGGAAAAAGTGTTAAAACTTCTCCTACTACACAAT
CTAAGATTTCAGAAATGGCCAAAGAATCCATACCATGCCCAACAGAAAGTGTTTACCCACCATTGGTGAACTGTGTGGCACCAGTTGACA
TCATTTTACCTCAGATTACATCAAACATGTGGGCAAGAGGCCTGGGACAACTCATTAGAGCTAAGAATATAAAAACTATTGGTGATTTGA
GTACTCTTACAGCATCTGAAATAAAAACTCTTCCTATCCGTTCTCCAAAAGTGTCCAATGTAAAAAAGGCTCTCAGAATATATCATGAGC
AGCAGGTGAAGACTCGTGGACTAGAAGAGATTCCAGTTTTTGATATTTCTGAAAAAACAGTAAATGGAATAGAAAATAAATCTTTGTCAC
CTGATGAAGAAAGACTTGTCTCAGATATAATTGATCCTGTTGCTTTAGAAATTCCATTATCCAAAAACCTTCTGGCACAGATTAGTGCTC
TTGCTCTTCAGCTGGATTCAGAAGATCTTCATAATTATTCAGGAAGCCAACTATTTGAAATGCACGAGAAACTAAGTTGTATGGCAAACT
CTGTAATAAAAAATCTACAGTCACGTTGGAGATCACCATCCCATGAAAATTCTATTTAGTATTTTCAGAGAAAATTGAAGGTTTTTTTAA
ACATCACTGGATTTCTTGATTGAGGAAACAAGTTCTGAAATAATAGCACAATTTCAAAGAAGAGACTCTTTGCAAAGTTGATAACATTTC
AAACCCTGAAGGACAGTGACTTATTATGTAAGTTCAATTTTGTAAGTTCATTATGTAAGATCCTTTTTTTTTTCATAATATGTATTCTTG
GCTGCTATGCGTGGTTTTTCAGGAAATTTAATTATCTTACTGAGATGTGAAAGCAAAACTAGTAACAGAACTTACATTTTATTTCATGCT

>80189_80189_2_SECISBP2-RIF1_SECISBP2_chr9_91934712_ENST00000375807_RIF1_chr2_152315324_ENST00000428287_length(amino acids)=1555AA_BP=61
MASEGPREPESEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTEPVLTQAKQKFLLLLPGLETVEMMEESSGP
YSDGTENSQLNVKISGMERKSNGKRDSFLAQTKNKKENMKPAAKLKLESSSLKVKGEILLEEEKSTDFVFIPPEGKDAKERILTDHQKEV
LKTKRCDIPAMYNNLDVSQDTLFTQYSQEEPMEIPTLTRKPKEDSKMMITEEQMDSDIVIPQDVTEDCGMAEHLEKSSLSNNECGSLDKT
SPEMSNSNNDERKKALISSRKTSTECASSTENSFVVSSSSVSNTTVAGTPPYPTSRRQTFITLEKFDGSENRPFSPSPLNNISSTVTVKN
NQETMIKTDFLPKAKQREGTFSKSDSEKIVNGTKRSSRRAGKAEQTGNKRSKPLMRSEPEKNTEESVEGIVVLENNPPGLLNQTECVSDN
QVHLSESTMEHDNTKLKAATVENAVLLETNTVEEKNVEINLESKENTPPVVISADQMVNEDSQVQITPNQKTLRRSSRRRSEVVESTTES
QDKENSHQKKERRKEEEKPLQKSPLHIKDDVLPKQKLIAEQTLQENLIEKGSNLHEKTLGETSANAETEQNKKKADPENIKSEGDGTQDI
VDKSSEKLVRGRTRYQTRRASQGLLSSIENSESDSSEAKEEGSRKKRSGKWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEED
VSIKSPICEKQDESNTVICQDSTVTSDLLQVPDDLPNVCEEKNETSKYAEYSFTSLPVPESNLRTRNAIKRLHKRDSFDNCSLGESSKIG
ISDISSLSEKTFQTLECQHKRSRRVRRSKGCDCCGEKSQPQEKSLIGLKNTENNDVEISETKKADVQAPVSPSETSQANPYSEGQFLDEH
HSVNFHLGLKEDNDTINDSLIVSETKSKENTMQESLPSGIVNFREEICDMDSSEAMSLESQESPNENFKTVGPCLGDSKNVSQESLETKE
EKPEETPKMELSLENVTVEGNACKVTESNLEKAKTMELNVGNEASFHGQERTKTGISEEAAIEENKRNDDSEADTAKLNAKEVATEEFNS
DISLSDNTTPVKLNAQTEISEQTAAGELDGGNDVSDLHSSEETNTKMKNNEEMMIGEAMAETGHDGETENEGITTKTSKPDEAETNMLTA
EMDNFVCDTVEMSTEEGIIDANKTETNTEYSKSEEKLDNNQMVMESDILQEDHHTSQKVEEPSQCLASGTAISELIIEDNNASPQKLREL
DPSLVSANDSPSGMQTRCVWSPLASPSTSILKRGLKRSQEDEISSPVNKVRRVSFADPIYQAGLADDIDRRCSIVRSHSSNSSPIGKSVK
TSPTTQSKISEMAKESIPCPTESVYPPLVNCVAPVDIILPQITSNMWARGLGQLIRAKNIKTIGDLSTLTASEIKTLPIRSPKVSNVKKA
LRIYHEQQVKTRGLEEIPVFDISEKTVNGIENKSLSPDEERLVSDIIDPVALEIPLSKNLLAQISALALQLDSEDLHNYSGSQLFEMHEK

--------------------------------------------------------------
>80189_80189_3_SECISBP2-RIF1_SECISBP2_chr9_91934712_ENST00000375807_RIF1_chr2_152315324_ENST00000430328_length(transcript)=5056nt_BP=253nt
GCTTTGTCTGTCCGGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCATGGCGTCGGAGGGGCCGC
GGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGT
CCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAACCAGTACTAACACAAG
CCAAACAAAAATTTCTGCTCCTGTTGCCTGGTTTGGAAACTGTTGAAATGATGGAGGAATCCAGTGGACCATATTCTGATGGAACAGAAA
ATTCACAACTAAATGTGAAGATAAGTGGCATGGAGAGAAAATCAAATGGAAAAAGAGATTCATTTTTGGCACAAACAAAGAATAAAAAAG
AAAATATGAAACCAGCAGCCAAACTGAAACTTGAATCTTCGTCTTTAAAAGTAAAGGGTGAAATTCTTTTGGAAGAGGAAAAGTCTACTG
ACTTTGTGTTTATACCTCCAGAAGGAAAAGATGCAAAGGAAAGAATATTAACTGATCATCAAAAAGAAGTTCTCAAAACAAAGCGGTGTG
ATATTCCTGCCATGTATAATAATCTGGATGTTTCCCAAGATACCTTATTTACTCAGTATAGTCAGGAAGAGCCTATGGAAATTCCTACTT
TAACCAGAAAACCAAAGGAGGATTCTAAGATGATGATTACGGAGGAGCAAATGGACAGTGACATTGTCATTCCTCAAGATGTCACGGAAG
ACTGTGGTATGGCTGAACATCTTGAAAAGTCCTCCCTTTCGAATAATGAGTGTGGTTCTCTTGACAAAACCAGTCCAGAAATGTCAAACA
GTAATAATGATGAAAGAAAAAAAGCTTTAATTTCATCAAGGAAAACATCAACTGAATGTGCATCTAGTACAGAAAATTCTTTCGTTGTCA
GCAGTAGTTCAGTTTCTAATACCACTGTTGCTGGAACTCCCCCATACCCTACAAGTCGGAGGCAAACCTTTATTACTTTGGAGAAGTTTG
ATGGTTCAGAAAATAGACCTTTTAGTCCATCCCCCTTGAATAATATTTCATCAACTGTTACAGTGAAAAATAACCAGGAAACCATGATTA
AAACAGATTTTCTACCAAAAGCAAAGCAAAGAGAAGGGACTTTTTCAAAATCTGATTCTGAAAAAATAGTGAATGGAACTAAGAGATCAA
GCCGGAGAGCTGGTAAAGCTGAACAAACAGGGAATAAAAGGTCTAAGCCCTTAATGAGATCTGAGCCGGAGAAAAATACTGAGGAATCTG
TTGAAGGCATTGTAGTCTTAGAAAATAACCCACCTGGTTTGCTTAATCAAACAGAATGTGTGTCAGATAATCAGGTTCATCTTTCTGAAT
CTACAATGGAGCATGACAATACAAAGCTTAAAGCAGCAACAGTGGAAAATGCTGTATTATTGGAAACTAATACTGTAGAGGAGAAAAATG
TAGAAATTAATTTGGAATCCAAAGAGAATACACCCCCAGTAGTAATATCAGCAGATCAAATGGTAAATGAGGATAGTCAGGTTCAGATAA
CTCCAAATCAGAAAACCCTTAGACGGTCTTCAAGGCGACGTTCAGAAGTAGTAGAGTCTACCACTGAAAGCCAAGATAAGGAAAATAGTC
ATCAAAAAAAGGAACGACGTAAGGAAGAAGAAAAACCTCTTCAGAAGAGTCCATTGCATATAAAAGATGATGTGTTACCTAAACAAAAAC
TGATTGCTGAACAAACTCTACAGGAGAATTTAATTGAGAAAGGAAGTAATTTACATGAGAAGACTCTTGGGGAAACTAGTGCTAATGCAG
AAACTGAACAAAATAAAAAAAAGGCAGACCCTGAGAACATTAAGTCTGAGGGGGATGGTACCCAGGACATTGTAGATAAGTCCTCTGAGA
AACTAGTCAGAGGCCGAACACGGTATCAAACTAGAAGAGCATCTCAGGGTTTGCTTTCCAGCATTGAAAACTCAGAATCTGATAGTTCGG
AGGCAAAAGAAGAAGGTTCTAGGAAGAAGAGATCTGGAAAATGGAAAAACAAAAGCAATGAAAGTGTTGACATTCAAGATCAAGAAGAGA
AAGTGGTGAAACAGGAATGTATAAAAGCTGAAAATCAGTCACATGATTATAAAGCAACTTCTGAAGAAGATGTAAGCATAAAATCTCCGA
TTTGCGAAAAACAAGATGAAAGTAATACTGTAATATGTCAGGATTCTACAGTAACTTCAGATTTGTTGCAAGTTCCTGATGATTTACCAA
ATGTGTGTGAGGAAAAAAATGAAACTAGCAAATATGCAGAATATTCCTTTACAAGTCTACCTGTGCCAGAATCAAATCTAAGGACTAGAA
ATGCCATTAAGAGATTACATAAGCGAGACTCTTTTGATAATTGTAGTTTGGGAGAATCCTCAAAAATAGGGATATCAGATATTTCTTCGC
TTTCAGAAAAAACTTTTCAAACACTTGAATGCCAACACAAGAGAAGTAGGAGGGTGAGGAGATCTAAAGGTTGTGATTGCTGTGGGGAAA
AATCACAACCTCAGGAAAAGTCACTCATTGGGTTAAAGAATACAGAAAATAATGACGTAGAGATTAGTGAAACAAAAAAGGCAGATGTGC
AAGCACCTGTAAGCCCATCAGAAACTTCTCAAGCTAATCCATATTCTGAAGGACAATTTTTAGATGAACATCATAGTGTGAATTTTCATT
TGGGTCTCAAAGAGGATAATGATACTATTAATGATTCATTAATTGTTTCTGAAACCAAATCAAAAGAAAACACTATGCAAGAATCTCTTC
CTTCTGGAATAGTAAACTTTAGAGAGGAAATTTGTGATATGGATTCTAGTGAAGCAATGTCTCTTGAAAGCCAGGAGTCACCTAATGAAA
ATTTTAAAACTGTTGGCCCGTGTTTAGGAGACTCGAAAAATGTTTCACAGGAATCTTTGGAGACAAAAGAAGAAAAACCAGAAGAAACCC
CAAAAATGGAACTGAGTCTAGAGAATGTTACTGTTGAAGGAAATGCATGTAAAGTAACAGAATCCAATCTAGAGAAAGCAAAAACTATGG
AATTGAATGTAGGAAATGAAGCTAGCTTTCATGGACAAGAGAGAACCAAAACTGGTATTTCTGAAGAAGCAGCAATAGAAGAAAATAAAA
GAAATGATGACTCTGAAGCAGACACAGCTAAACTGAATGCCAAAGAAGTAGCAACTGAGGAATTTAATTCAGATATTAGTCTTTCTGATA
ATACTACACCTGTAAAATTGAATGCTCAAACTGAGATTTCTGAACAAACAGCAGCTGGGGAACTAGATGGAGGAAATGATGTATCTGATC
TACACTCATCTGAAGAAACGAATACCAAAATGAAAAATAATGAAGAAATGATGATCGGCGAGGCAATGGCTGAAACTGGCCATGATGGTG
AAACAGAGAATGAGGGCATAACTACCAAAACCTCAAAGCCTGATGAAGCTGAAACAAACATGTTGACTGCAGAAATGGACAACTTTGTTT
GTGACACAGTTGAAATGAGCACTGAAGAAGGAATCATTGACGCTAATAAAACTGAAACAAATACTGAGTATAGTAAATCTGAAGAAAAAT
TAGATAACAATCAAATGGTAATGGAAAGTGATATTTTACAGGAAGATCACCATACTTCACAGAAAGTGGAGGAACCATCACAGTGTCTGG
CATCTGGAACAGCTATCTCTGAGCTAATAATAGAAGACAATAATGCATCTCCTCAAAAACTAAGGGAACTTGATCCTTCACTTGTGTCAG
CAAATGACAGTCCTAGTGGCATGCAGACACGCTGTGTCTGGTCTCCTTTGGCTTCTCCGTCTACGAGCATTTTAAAGAGAGGACTAAAAA
GATCCCAAGAAGATGAAATCTCATCACCTGTTAATAAGGTTCGCCGTGTCTCCTTTGCAGATCCAATATACCAAGCAGGATTGGCAGATG
ACATTGATAGACGGTGCTCTATTGTTAGGTCCCATTCTTCCAATAGTTCTCCCATAGGAAAAAGTGTTAAAACTTCTCCTACTACACAAT
CTAAGATTTCAGAAATGGCCAAAGAATCCATACCATGCCCAACAGAAAGTGTTTACCCACCATTGGTGAACTGTGTGGCACCAGTTGACA
TCATTTTACCTCAGATTACATCAAACATGTGGGCAAGAGGCCTGGGACAACTCATTAGAGCTAAGAATATAAAAACTATTGGTGATTTGA
GTACTCTTACAGCATCTGAAATAAAAACTCTTCCTATCCGTTCTCCAAAAGTGTCCAATGTAAAAAAGGCTCTCAGAATATATCATGAGC
AGCAGGTGAAGACTCGTGGACTAGAAGAGATTCCAGTTTTTGATATTTCTGAAAAAACAGTAAATGGAATAGAAAATAAATCTTTGTCAC
CTGATGAAGAAAGACTTGTCTCAGATATAATTGATCCTGTTGCTTTAGAAATTCCATTATCCAAAAACCTTCTGGCACAGATTAGTGCTC
TTGCTCTTCAGCTGGATTCAGAAGATCTTCATAATTATTCAGGAAGCCAACTATTTGAAATGCACGAGAAACTAAGTTGTATGGCAAACT
CTGTAATAAAAAATCTACAGTCACGTTGGAGATCACCATCCCATGAAAATTCTATTTAGTATTTTCAGAGAAAATTGAAGGTTTTTTTAA
ACATCACTGGATTTCTTGATTGAGGAAACAAGTTCTGAAATAATAGCACAATTTCAAAGAAGAGACTCTTTGCAAAGTTGATAACATTTC
AAACCCTGAAGGACAGTGACTTATTATGTAAGTTCAATTTTGTAAGTTCATTATGTAAGATCCTTTTTTTTTTCATAATATGTATTCTTG
GCTGCTATGCGTGGTTTTTCAGGAAATTTAATTATCTTACTGAGATGTGAAAGCAAAACTAGTAACAGAACTTACATTTTATTTCATGCT

>80189_80189_3_SECISBP2-RIF1_SECISBP2_chr9_91934712_ENST00000375807_RIF1_chr2_152315324_ENST00000430328_length(amino acids)=1555AA_BP=61
MASEGPREPESEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTEPVLTQAKQKFLLLLPGLETVEMMEESSGP
YSDGTENSQLNVKISGMERKSNGKRDSFLAQTKNKKENMKPAAKLKLESSSLKVKGEILLEEEKSTDFVFIPPEGKDAKERILTDHQKEV
LKTKRCDIPAMYNNLDVSQDTLFTQYSQEEPMEIPTLTRKPKEDSKMMITEEQMDSDIVIPQDVTEDCGMAEHLEKSSLSNNECGSLDKT
SPEMSNSNNDERKKALISSRKTSTECASSTENSFVVSSSSVSNTTVAGTPPYPTSRRQTFITLEKFDGSENRPFSPSPLNNISSTVTVKN
NQETMIKTDFLPKAKQREGTFSKSDSEKIVNGTKRSSRRAGKAEQTGNKRSKPLMRSEPEKNTEESVEGIVVLENNPPGLLNQTECVSDN
QVHLSESTMEHDNTKLKAATVENAVLLETNTVEEKNVEINLESKENTPPVVISADQMVNEDSQVQITPNQKTLRRSSRRRSEVVESTTES
QDKENSHQKKERRKEEEKPLQKSPLHIKDDVLPKQKLIAEQTLQENLIEKGSNLHEKTLGETSANAETEQNKKKADPENIKSEGDGTQDI
VDKSSEKLVRGRTRYQTRRASQGLLSSIENSESDSSEAKEEGSRKKRSGKWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEED
VSIKSPICEKQDESNTVICQDSTVTSDLLQVPDDLPNVCEEKNETSKYAEYSFTSLPVPESNLRTRNAIKRLHKRDSFDNCSLGESSKIG
ISDISSLSEKTFQTLECQHKRSRRVRRSKGCDCCGEKSQPQEKSLIGLKNTENNDVEISETKKADVQAPVSPSETSQANPYSEGQFLDEH
HSVNFHLGLKEDNDTINDSLIVSETKSKENTMQESLPSGIVNFREEICDMDSSEAMSLESQESPNENFKTVGPCLGDSKNVSQESLETKE
EKPEETPKMELSLENVTVEGNACKVTESNLEKAKTMELNVGNEASFHGQERTKTGISEEAAIEENKRNDDSEADTAKLNAKEVATEEFNS
DISLSDNTTPVKLNAQTEISEQTAAGELDGGNDVSDLHSSEETNTKMKNNEEMMIGEAMAETGHDGETENEGITTKTSKPDEAETNMLTA
EMDNFVCDTVEMSTEEGIIDANKTETNTEYSKSEEKLDNNQMVMESDILQEDHHTSQKVEEPSQCLASGTAISELIIEDNNASPQKLREL
DPSLVSANDSPSGMQTRCVWSPLASPSTSILKRGLKRSQEDEISSPVNKVRRVSFADPIYQAGLADDIDRRCSIVRSHSSNSSPIGKSVK
TSPTTQSKISEMAKESIPCPTESVYPPLVNCVAPVDIILPQITSNMWARGLGQLIRAKNIKTIGDLSTLTASEIKTLPIRSPKVSNVKKA
LRIYHEQQVKTRGLEEIPVFDISEKTVNGIENKSLSPDEERLVSDIIDPVALEIPLSKNLLAQISALALQLDSEDLHNYSGSQLFEMHEK

--------------------------------------------------------------
>80189_80189_4_SECISBP2-RIF1_SECISBP2_chr9_91934712_ENST00000375807_RIF1_chr2_152315324_ENST00000444746_length(transcript)=5134nt_BP=253nt
GCTTTGTCTGTCCGGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCATGGCGTCGGAGGGGCCGC
GGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGT
CCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAACCAGTACTAACACAAG
CCAAACAAAAATTTCTGCTCCTGTTGCCTGGTTTGGAAACTGTTGAAATGATGGAGGAATCCAGTGGACCATATTCTGATGGAACAGAAA
ATTCACAACTAAATGTGAAGATAAGTGGCATGGAGAGAAAATCAAATGGAAAAAGAGATTCATTTTTGGCACAAACAAAGAATAAAAAAG
AAAATATGAAACCAGCAGCCAAACTGAAACTTGAATCTTCGTCTTTAAAAGTAAAGGGTGAAATTCTTTTGGAAGAGGAAAAGTCTACTG
ACTTTGTGTTTATACCTCCAGAAGGAAAAGATGCAAAGGAAAGAATATTAACTGATCATCAAAAAGAAGTTCTCAAAACAAAGCGGTGTG
ATATTCCTGCCATGTATAATAATCTGGATGTTTCCCAAGATACCTTATTTACTCAGTATAGTCAGGAAGAGCCTATGGAAATTCCTACTT
TAACCAGAAAACCAAAGGAGGATTCTAAGATGATGATTACGGAGGAGCAAATGGACAGTGACATTGTCATTCCTCAAGATGTCACGGAAG
ACTGTGGTATGGCTGAACATCTTGAAAAGTCCTCCCTTTCGAATAATGAGTGTGGTTCTCTTGACAAAACCAGTCCAGAAATGTCAAACA
GTAATAATGATGAAAGAAAAAAAGCTTTAATTTCATCAAGGAAAACATCAACTGAATGTGCATCTAGTACAGAAAATTCTTTCGTTGTCA
GCAGTAGTTCAGTTTCTAATACCACTGTTGCTGGAACTCCCCCATACCCTACAAGTCGGAGGCAAACCTTTATTACTTTGGAGAAGTTTG
ATGGTTCAGAAAATAGACCTTTTAGTCCATCCCCCTTGAATAATATTTCATCAACTGTTACAGTGAAAAATAACCAGGAAACCATGATTA
AAACAGATTTTCTACCAAAAGCAAAGCAAAGAGAAGGGACTTTTTCAAAATCTGATTCTGAAAAAATAGTGAATGGAACTAAGAGATCAA
GCCGGAGAGCTGGTAAAGCTGAACAAACAGGGAATAAAAGGTCTAAGCCCTTAATGAGATCTGAGCCGGAGAAAAATACTGAGGAATCTG
TTGAAGGCATTGTAGTCTTAGAAAATAACCCACCTGGTTTGCTTAATCAAACAGAATGTGTGTCAGATAATCAGGTTCATCTTTCTGAAT
CTACAATGGAGCATGACAATACAAAGCTTAAAGCAGCAACAGTGGAAAATGCTGTATTATTGGAAACTAATACTGTAGAGGAGAAAAATG
TAGAAATTAATTTGGAATCCAAAGAGAATACACCCCCAGTAGTAATATCAGCAGATCAAATGGTAAATGAGGATAGTCAGGTTCAGATAA
CTCCAAATCAGAAAACCCTTAGACGGTCTTCAAGGCGACGTTCAGAAGTAGTAGAGTCTACCACTGAAAGCCAAGATAAGGAAAATAGTC
ATCAAAAAAAGGAACGACGTAAGGAAGAAGAAAAACCTCTTCAGAAGAGTCCATTGCATATAAAAGATGATGTGTTACCTAAACAAAAAC
TGATTGCTGAACAAACTCTACAGGAGAATTTAATTGAGAAAGGAAGTAATTTACATGAGAAGACTCTTGGGGAAACTAGTGCTAATGCAG
AAACTGAACAAAATAAAAAAAAGGCAGACCCTGAGAACATTAAGTCTGAGGGGGATGGTACCCAGGACATTGTAGATAAGTCCTCTGAGA
AACTAGTCAGAGGCCGAACACGGTATCAAACTAGAAGAGCATCTCAGGGTTTGCTTTCCAGCATTGAAAACTCAGAATCTGATAGTTCGG
AGGCAAAAGAAGAAGGTTCTAGGAAGAAGAGATCTGGAAAATGGAAAAACAAAAGCAATGAAAGTGTTGACATTCAAGATCAAGAAGAGA
AAGTGGTGAAACAGGAATGTATAAAAGCTGAAAATCAGTCACATGATTATAAAGCAACTTCTGAAGAAGATGTAAGCATAAAATCTCCGA
TTTGCGAAAAACAAGATGAAAGTAATACTGTAATATGTCAGGATTCTACAGTAACTTCAGATTTGTTGCAAGTTCCTGATGATTTACCAA
ATGTGTGTGAGGAAAAAAATGAAACTAGCAAATATGCAGAATATTCCTTTACAAGTCTACCTGTGCCAGAATCAAATCTAAGGACTAGAA
ATGCCATTAAGAGATTACATAAGCGAGACTCTTTTGATAATTGTAGTTTGGGAGAATCCTCAAAAATAGGGATATCAGATATTTCTTCGC
TTTCAGAAAAAACTTTTCAAACACTTGAATGCCAACACAAGAGAAGTAGGAGGGTGAGGAGATCTAAAGGTTGTGATTGCTGTGGGGAAA
AATCACAACCTCAGGAAAAGTCACTCATTGGGTTAAAGAATACAGAAAATAATGACGTAGAGATTAGTGAAACAAAAAAGGCAGATGTGC
AAGCACCTGTAAGCCCATCAGAAACTTCTCAAGCTAATCCATATTCTGAAGGACAATTTTTAGATGAACATCATAGTGTGAATTTTCATT
TGGGTCTCAAAGAGGATAATGATACTATTAATGATTCATTAATTGTTTCTGAAACCAAATCAAAAGAAAACACTATGCAAGAATCTCTTC
CTTCTGGAATAGTAAACTTTAGAGAGGAAATTTGTGATATGGATTCTAGTGAAGCAATGTCTCTTGAAAGCCAGGAGTCACCTAATGAAA
ATTTTAAAACTGTTGGCCCGTGTTTAGGAGACTCGAAAAATGTTTCACAGGAATCTTTGGAGACAAAAGAAGAAAAACCAGAAGAAACCC
CAAAAATGGAACTGAGTCTAGAGAATGTTACTGTTGAAGGAAATGCATGTAAAGTAACAGAATCCAATCTAGAGAAAGCAAAAACTATGG
AATTGAATGTAGGAAATGAAGCTAGCTTTCATGGACAAGAGAGAACCAAAACTGGTATTTCTGAAGAAGCAGCAATAGAAGAAAATAAAA
GAAATGATGACTCTGAAGCAGACACAGCTAAACTGAATGCCAAAGAAGTAGCAACTGAGGAATTTAATTCAGATATTAGTCTTTCTGATA
ATACTACACCTGTAAAATTGAATGCTCAAACTGAGATTTCTGAACAAACAGCAGCTGGGGAACTAGATGGAGGAAATGATGTATCTGATC
TACACTCATCTGAAGAAACGAATACCAAAATGAAAAATAATGAAGAAATGATGATCGGCGAGGCAATGGCTGAAACTGGCCATGATGGTG
AAACAGAGAATGAGGGCATAACTACCAAAACCTCAAAGCCTGATGAAGCTGAAACAAACATGTTGACTGCAGAAATGGACAACTTTGTTT
GTGACACAGTTGAAATGAGCACTGAAGAAGGAATCATTGACGCTAATAAAACTGAAACAAATACTGAGTATAGTAAATCTGAAGAAAAAT
TAGATAACAATCAAATGGTAATGGAAAGTGATATTTTACAGGAAGATCACCATACTTCACAGAAAGTGGAGGAACCATCACAGTGTCTGG
CATCTGGAACAGCTATCTCTGAGCTAATAATAGAAGACAATAATGCATCTCCTCAAAAACTAAGGGAACTTGATCCTTCACTTGTGTCAG
CAAATGACAGTCCTAGTGGCATGCAGACACGCTGTGTCTGGTCTCCTTTGGCTTCTCCGTCTACGAGCATTTTAAAGAGAGGACTAAAAA
GATCCCAAGAAGATGAAATCTCATCACCTGTTAATAAGGTTCGCCGTGTCTCCTTTGCAGATCCAATATACCAAGCAGGATTGGCAGATG
ACATTGATAGACGGTGCTCTATTGTTAGGTCCCATTCTTCCAATAGTTCTCCCATAGGAAAAAGTGTTAAAACTTCTCCTACTACACAAT
CTAAGCATAATACCACTTCAGCCAAAGGATTTCTGTCCCCAGGATCACGTAGCCCTAAATTTAAGAGCTCAAAGAAGTGTTTAATTTCAG
AAATGGCCAAAGAATCCATACCATGCCCAACAGAAAGTGTTTACCCACCATTGGTGAACTGTGTGGCACCAGTTGACATCATTTTACCTC
AGATTACATCAAACATGTGGGCAAGAGGCCTGGGACAACTCATTAGAGCTAAGAATATAAAAACTATTGGTGATTTGAGTACTCTTACAG
CATCTGAAATAAAAACTCTTCCTATCCGTTCTCCAAAAGTGTCCAATGTAAAAAAGGCTCTCAGAATATATCATGAGCAGCAGGTGAAGA
CTCGTGGACTAGAAGAGATTCCAGTTTTTGATATTTCTGAAAAAACAGTAAATGGAATAGAAAATAAATCTTTGTCACCTGATGAAGAAA
GACTTGTCTCAGATATAATTGATCCTGTTGCTTTAGAAATTCCATTATCCAAAAACCTTCTGGCACAGATTAGTGCTCTTGCTCTTCAGC
TGGATTCAGAAGATCTTCATAATTATTCAGGAAGCCAACTATTTGAAATGCACGAGAAACTAAGTTGTATGGCAAACTCTGTAATAAAAA
ATCTACAGTCACGTTGGAGATCACCATCCCATGAAAATTCTATTTAGTATTTTCAGAGAAAATTGAAGGTTTTTTTAAACATCACTGGAT
TTCTTGATTGAGGAAACAAGTTCTGAAATAATAGCACAATTTCAAAGAAGAGACTCTTTGCAAAGTTGATAACATTTCAAACCCTGAAGG
ACAGTGACTTATTATGTAAGTTCAATTTTGTAAGTTCATTATGTAAGATCCTTTTTTTTTTCATAATATGTATTCTTGGCTGCTATGCGT
GGTTTTTCAGGAAATTTAATTATCTTACTGAGATGTGAAAGCAAAACTAGTAACAGAACTTACATTTTATTTCATGCTTTCTTAAACCCG

>80189_80189_4_SECISBP2-RIF1_SECISBP2_chr9_91934712_ENST00000375807_RIF1_chr2_152315324_ENST00000444746_length(amino acids)=1581AA_BP=61
MASEGPREPESEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTEPVLTQAKQKFLLLLPGLETVEMMEESSGP
YSDGTENSQLNVKISGMERKSNGKRDSFLAQTKNKKENMKPAAKLKLESSSLKVKGEILLEEEKSTDFVFIPPEGKDAKERILTDHQKEV
LKTKRCDIPAMYNNLDVSQDTLFTQYSQEEPMEIPTLTRKPKEDSKMMITEEQMDSDIVIPQDVTEDCGMAEHLEKSSLSNNECGSLDKT
SPEMSNSNNDERKKALISSRKTSTECASSTENSFVVSSSSVSNTTVAGTPPYPTSRRQTFITLEKFDGSENRPFSPSPLNNISSTVTVKN
NQETMIKTDFLPKAKQREGTFSKSDSEKIVNGTKRSSRRAGKAEQTGNKRSKPLMRSEPEKNTEESVEGIVVLENNPPGLLNQTECVSDN
QVHLSESTMEHDNTKLKAATVENAVLLETNTVEEKNVEINLESKENTPPVVISADQMVNEDSQVQITPNQKTLRRSSRRRSEVVESTTES
QDKENSHQKKERRKEEEKPLQKSPLHIKDDVLPKQKLIAEQTLQENLIEKGSNLHEKTLGETSANAETEQNKKKADPENIKSEGDGTQDI
VDKSSEKLVRGRTRYQTRRASQGLLSSIENSESDSSEAKEEGSRKKRSGKWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEED
VSIKSPICEKQDESNTVICQDSTVTSDLLQVPDDLPNVCEEKNETSKYAEYSFTSLPVPESNLRTRNAIKRLHKRDSFDNCSLGESSKIG
ISDISSLSEKTFQTLECQHKRSRRVRRSKGCDCCGEKSQPQEKSLIGLKNTENNDVEISETKKADVQAPVSPSETSQANPYSEGQFLDEH
HSVNFHLGLKEDNDTINDSLIVSETKSKENTMQESLPSGIVNFREEICDMDSSEAMSLESQESPNENFKTVGPCLGDSKNVSQESLETKE
EKPEETPKMELSLENVTVEGNACKVTESNLEKAKTMELNVGNEASFHGQERTKTGISEEAAIEENKRNDDSEADTAKLNAKEVATEEFNS
DISLSDNTTPVKLNAQTEISEQTAAGELDGGNDVSDLHSSEETNTKMKNNEEMMIGEAMAETGHDGETENEGITTKTSKPDEAETNMLTA
EMDNFVCDTVEMSTEEGIIDANKTETNTEYSKSEEKLDNNQMVMESDILQEDHHTSQKVEEPSQCLASGTAISELIIEDNNASPQKLREL
DPSLVSANDSPSGMQTRCVWSPLASPSTSILKRGLKRSQEDEISSPVNKVRRVSFADPIYQAGLADDIDRRCSIVRSHSSNSSPIGKSVK
TSPTTQSKHNTTSAKGFLSPGSRSPKFKSSKKCLISEMAKESIPCPTESVYPPLVNCVAPVDIILPQITSNMWARGLGQLIRAKNIKTIG
DLSTLTASEIKTLPIRSPKVSNVKKALRIYHEQQVKTRGLEEIPVFDISEKTVNGIENKSLSPDEERLVSDIIDPVALEIPLSKNLLAQI

--------------------------------------------------------------
>80189_80189_5_SECISBP2-RIF1_SECISBP2_chr9_91934712_ENST00000375807_RIF1_chr2_152315324_ENST00000453091_length(transcript)=5290nt_BP=253nt
GCTTTGTCTGTCCGGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCATGGCGTCGGAGGGGCCGC
GGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGT
CCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAACCAGTACTAACACAAG
CCAAACAAAAATTTCTGCTCCTGTTGCCTGGTTTGGAAACTGTTGAAATGATGGAGGAATCCAGTGGACCATATTCTGATGGAACAGAAA
ATTCACAACTAAATGTGAAGATAAGTGGCATGGAGAGAAAATCAAATGGAAAAAGAGATTCATTTTTGGCACAAACAAAGAATAAAAAAG
AAAATATGAAACCAGCAGCCAAACTGAAACTTGAATCTTCGTCTTTAAAAGTAAAGGGTGAAATTCTTTTGGAAGAGGAAAAGTCTACTG
ACTTTGTGTTTATACCTCCAGAAGGAAAAGATGCAAAGGAAAGAATATTAACTGATCATCAAAAAGAAGTTCTCAAAACAAAGCGGTGTG
ATATTCCTGCCATGTATAATAATCTGGATGTTTCCCAAGATACCTTATTTACTCAGTATAGTCAGGAAGAGCCTATGGAAATTCCTACTT
TAACCAGAAAACCAAAGGAGGATTCTAAGATGATGATTACGGAGGAGCAAATGGACAGTGACATTGTCATTCCTCAAGATGTCACGGAAG
ACTGTGGTATGGCTGAACATCTTGAAAAGTCCTCCCTTTCGAATAATGAGTGTGGTTCTCTTGACAAAACCAGTCCAGAAATGTCAAACA
GTAATAATGATGAAAGAAAAAAAGCTTTAATTTCATCAAGGAAAACATCAACTGAATGTGCATCTAGTACAGAAAATTCTTTCGTTGTCA
GCAGTAGTTCAGTTTCTAATACCACTGTTGCTGGAACTCCCCCATACCCTACAAGTCGGAGGCAAACCTTTATTACTTTGGAGAAGTTTG
ATGGTTCAGAAAATAGACCTTTTAGTCCATCCCCCTTGAATAATATTTCATCAACTGTTACAGTGAAAAATAACCAGGAAACCATGATTA
AAACAGATTTTCTACCAAAAGCAAAGCAAAGAGAAGGGACTTTTTCAAAATCTGATTCTGAAAAAATAGTGAATGGAACTAAGAGATCAA
GCCGGAGAGCTGGTAAAGCTGAACAAACAGGGAATAAAAGGTCTAAGCCCTTAATGAGATCTGAGCCGGAGAAAAATACTGAGGAATCTG
TTGAAGGCATTGTAGTCTTAGAAAATAACCCACCTGGTTTGCTTAATCAAACAGAATGTGTGTCAGATAATCAGGTTCATCTTTCTGAAT
CTACAATGGAGCATGACAATACAAAGCTTAAAGCAGCAACAGTGGAAAATGCTGTATTATTGGAAACTAATACTGTAGAGGAGAAAAATG
TAGAAATTAATTTGGAATCCAAAGAGAATACACCCCCAGTAGTAATATCAGCAGATCAAATGGTAAATGAGGATAGTCAGGTTCAGATAA
CTCCAAATCAGAAAACCCTTAGACGGTCTTCAAGGCGACGTTCAGAAGTAGTAGAGTCTACCACTGAAAGCCAAGATAAGGAAAATAGTC
ATCAAAAAAAGGAACGACGTAAGGAAGAAGAAAAACCTCTTCAGAAGAGTCCATTGCATATAAAAGATGATGTGTTACCTAAACAAAAAC
TGATTGCTGAACAAACTCTACAGGAGAATTTAATTGAGAAAGGAAGTAATTTACATGAGAAGACTCTTGGGGAAACTAGTGCTAATGCAG
AAACTGAACAAAATAAAAAAAAGGCAGACCCTGAGAACATTAAGTCTGAGGGGGATGGTACCCAGGACATTGTAGATAAGTCCTCTGAGA
AACTAGTCAGAGGCCGAACACGGTATCAAACTAGAAGAGCATCTCAGGGTTTGCTTTCCAGCATTGAAAACTCAGAATCTGATAGTTCGG
AGGCAAAAGAAGAAGGTTCTAGGAAGAAGAGATCTGGAAAATGGAAAAACAAAAGCAATGAAAGTGTTGACATTCAAGATCAAGAAGAGA
AAGTGGTGAAACAGGAATGTATAAAAGCTGAAAATCAGTCACATGATTATAAAGCAACTTCTGAAGAAGATGTAAGCATAAAATCTCCGA
TTTGCGAAAAACAAGATGAAAGTAATACTGTAATATGTCAGGATTCTACAGTAACTTCAGATTTGTTGCAAGTTCCTGATGATTTACCAA
ATGTGTGTGAGGAAAAAAATGAAACTAGCAAATATGCAGAATATTCCTTTACAAGTCTACCTGTGCCAGAATCAAATCTAAGGACTAGAA
ATGCCATTAAGAGATTACATAAGCGAGACTCTTTTGATAATTGTAGTTTGGGAGAATCCTCAAAAATAGGGATATCAGATATTTCTTCGC
TTTCAGAAAAAACTTTTCAAACACTTGAATGCCAACACAAGAGAAGTAGGAGGGTGAGGAGATCTAAAGGTTGTGATTGCTGTGGGGAAA
AATCACAACCTCAGGAAAAGTCACTCATTGGGTTAAAGAATACAGAAAATAATGACGTAGAGATTAGTGAAACAAAAAAGGCAGATGTGC
AAGCACCTGTAAGCCCATCAGAAACTTCTCAAGCTAATCCATATTCTGAAGGACAATTTTTAGATGAACATCATAGTGTGAATTTTCATT
TGGGTCTCAAAGAGGATAATGATACTATTAATGATTCATTAATTGTTTCTGAAACCAAATCAAAAGAAAACACTATGCAAGAATCTCTTC
CTTCTGGAATAGTAAACTTTAGAGAGGAAATTTGTGATATGGATTCTAGTGAAGCAATGTCTCTTGAAAGCCAGGAGTCACCTAATGAAA
ATTTTAAAACTGTTGGCCCGTGTTTAGGAGACTCGAAAAATGTTTCACAGGAATCTTTGGAGACAAAAGAAGAAAAACCAGAAGAAACCC
CAAAAATGGAACTGAGTCTAGAGAATGTTACTGTTGAAGGAAATGCATGTAAAGTAACAGAATCCAATCTAGAGAAAGCAAAAACTATGG
AATTGAATGTAGGAAATGAAGCTAGCTTTCATGGACAAGAGAGAACCAAAACTGGTATTTCTGAAGAAGCAGCAATAGAAGAAAATAAAA
GAAATGATGACTCTGAAGCAGACACAGCTAAACTGAATGCCAAAGAAGTAGCAACTGAGGAATTTAATTCAGATATTAGTCTTTCTGATA
ATACTACACCTGTAAAATTGAATGCTCAAACTGAGATTTCTGAACAAACAGCAGCTGGGGAACTAGATGGAGGAAATGATGTATCTGATC
TACACTCATCTGAAGAAACGAATACCAAAATGAAAAATAATGAAGAAATGATGATCGGCGAGGCAATGGCTGAAACTGGCCATGATGGTG
AAACAGAGAATGAGGGCATAACTACCAAAACCTCAAAGCCTGATGAAGCTGAAACAAACATGTTGACTGCAGAAATGGACAACTTTGTTT
GTGACACAGTTGAAATGAGCACTGAAGAAGGAATCATTGACGCTAATAAAACTGAAACAAATACTGAGTATAGTAAATCTGAAGAAAAAT
TAGATAACAATCAAATGGTAATGGAAAGTGATATTTTACAGGAAGATCACCATACTTCACAGAAAGTGGAGGAACCATCACAGTGTCTGG
CATCTGGAACAGCTATCTCTGAGCTAATAATAGAAGACAATAATGCATCTCCTCAAAAACTAAGGGAACTTGATCCTTCACTTGTGTCAG
CAAATGACAGTCCTAGTGGCATGCAGACACGCTGTGTCTGGTCTCCTTTGGCTTCTCCGTCTACGAGCATTTTAAAGAGAGGACTAAAAA
GATCCCAAGAAGATGAAATCTCATCACCTGTTAATAAGGTTCGCCGTGTCTCCTTTGCAGATCCAATATACCAAGCAGGATTGGCAGATG
ACATTGATAGACGGTGCTCTATTGTTAGGTCCCATTCTTCCAATAGTTCTCCCATAGGAAAAAGTGTTAAAACTTCTCCTACTACACAAT
CTAAGATTTCAGAAATGGCCAAAGAATCCATACCATGCCCAACAGAAAGTGTTTACCCACCATTGGTGAACTGTGTGGCACCAGTTGACA
TCATTTTACCTCAGATTACATCAAACATGTGGGCAAGAGGCCTGGGACAACTCATTAGAGCTAAGAATATAAAAACTATTGGTGATTTGA
GTACTCTTACAGCATCTGAAATAAAAACTCTTCCTATCCGTTCTCCAAAAGTGTCCAATGTAAAAAAGGCTCTCAGAATATATCATGAGC
AGCAGGTGAAGACTCGTGGACTAGAAGAGATTCCAGTTTTTGATATTTCTGAAAAAACAGTAAATGGAATAGAAAATAAATCTTTGTCAC
CTGATGAAGAAAGACTTGTCTCAGATATAATTGATCCTGTTGCTTTAGAAATTCCATTATCCAAAAACCTTCTGGCACAGATTAGTGCTC
TTGCTCTTCAGCTGGATTCAGAAGATCTTCATAATTATTCAGGAAGCCAACTATTTGAAATGCACGAGAAACTAAGTTGTATGGCAAACT
CTGTAATAAAAAATCTACAGTCACGTTGGAGATCACCATCCCATGAAAATTCTATTTAGTATTTTCAGAGAAAATTGAAGGTTTTTTTAA
ACATCACTGGATTTCTTGATTGAGGAAACAAGTTCTGAAATAATAGCACAATTTCAAAGAAGAGACTCTTTGCAAAGTTGATAACATTTC
AAACCCTGAAGGACAGTGACTTATTATGTAAGTTCAATTTTGTAAGTTCATTATGTAAGATCCTTTTTTTTTTCATAATATGTATTCTTG
GCTGCTATGCGTGGTTTTTCAGGAAATTTAATTATCTTACTGAGATGTGAAAGCAAAACTAGTAACAGAACTTACATTTTATTTCATGCT
TTCTTAAACCCGTGCATATTCTGGTGAAACATGTAAAATACTTTAAGTAAAATTGAACATTTTTATTTGAATTTTTGCTGAACTGATAAA
GGTGTTTATATTTTTGTTTGTTGGTTTGTTTAATTCATGTTTGTTGGGACTGAGGTTTAGGAAGTTTGTTACTGGTTAAAAACCTCAAAT

>80189_80189_5_SECISBP2-RIF1_SECISBP2_chr9_91934712_ENST00000375807_RIF1_chr2_152315324_ENST00000453091_length(amino acids)=1555AA_BP=61
MASEGPREPESEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTEPVLTQAKQKFLLLLPGLETVEMMEESSGP
YSDGTENSQLNVKISGMERKSNGKRDSFLAQTKNKKENMKPAAKLKLESSSLKVKGEILLEEEKSTDFVFIPPEGKDAKERILTDHQKEV
LKTKRCDIPAMYNNLDVSQDTLFTQYSQEEPMEIPTLTRKPKEDSKMMITEEQMDSDIVIPQDVTEDCGMAEHLEKSSLSNNECGSLDKT
SPEMSNSNNDERKKALISSRKTSTECASSTENSFVVSSSSVSNTTVAGTPPYPTSRRQTFITLEKFDGSENRPFSPSPLNNISSTVTVKN
NQETMIKTDFLPKAKQREGTFSKSDSEKIVNGTKRSSRRAGKAEQTGNKRSKPLMRSEPEKNTEESVEGIVVLENNPPGLLNQTECVSDN
QVHLSESTMEHDNTKLKAATVENAVLLETNTVEEKNVEINLESKENTPPVVISADQMVNEDSQVQITPNQKTLRRSSRRRSEVVESTTES
QDKENSHQKKERRKEEEKPLQKSPLHIKDDVLPKQKLIAEQTLQENLIEKGSNLHEKTLGETSANAETEQNKKKADPENIKSEGDGTQDI
VDKSSEKLVRGRTRYQTRRASQGLLSSIENSESDSSEAKEEGSRKKRSGKWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEED
VSIKSPICEKQDESNTVICQDSTVTSDLLQVPDDLPNVCEEKNETSKYAEYSFTSLPVPESNLRTRNAIKRLHKRDSFDNCSLGESSKIG
ISDISSLSEKTFQTLECQHKRSRRVRRSKGCDCCGEKSQPQEKSLIGLKNTENNDVEISETKKADVQAPVSPSETSQANPYSEGQFLDEH
HSVNFHLGLKEDNDTINDSLIVSETKSKENTMQESLPSGIVNFREEICDMDSSEAMSLESQESPNENFKTVGPCLGDSKNVSQESLETKE
EKPEETPKMELSLENVTVEGNACKVTESNLEKAKTMELNVGNEASFHGQERTKTGISEEAAIEENKRNDDSEADTAKLNAKEVATEEFNS
DISLSDNTTPVKLNAQTEISEQTAAGELDGGNDVSDLHSSEETNTKMKNNEEMMIGEAMAETGHDGETENEGITTKTSKPDEAETNMLTA
EMDNFVCDTVEMSTEEGIIDANKTETNTEYSKSEEKLDNNQMVMESDILQEDHHTSQKVEEPSQCLASGTAISELIIEDNNASPQKLREL
DPSLVSANDSPSGMQTRCVWSPLASPSTSILKRGLKRSQEDEISSPVNKVRRVSFADPIYQAGLADDIDRRCSIVRSHSSNSSPIGKSVK
TSPTTQSKISEMAKESIPCPTESVYPPLVNCVAPVDIILPQITSNMWARGLGQLIRAKNIKTIGDLSTLTASEIKTLPIRSPKVSNVKKA
LRIYHEQQVKTRGLEEIPVFDISEKTVNGIENKSLSPDEERLVSDIIDPVALEIPLSKNLLAQISALALQLDSEDLHNYSGSQLFEMHEK

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Fusion Gene PPI Analysis for SECISBP2-RIF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneRIF1chr9:91934712chr2:152315324ENST0000024332622351924_2472951.66666666666662473.0condensed chromosomes in telophase
TgeneRIF1chr9:91934712chr2:152315324ENST0000042828723351924_2472951.66666666666662447.0condensed chromosomes in telophase
TgeneRIF1chr9:91934712chr2:152315324ENST0000043032822341924_2472951.66666666666662447.0condensed chromosomes in telophase
TgeneRIF1chr9:91934712chr2:152315324ENST0000044474623361924_2472951.66666666666662473.0condensed chromosomes in telophase
TgeneRIF1chr9:91934712chr2:152315324ENST0000045309123351924_2472951.66666666666662447.0condensed chromosomes in telophase
TgeneRIF1chr9:91934712chr2:152315324ENST0000024332622352170_2446951.66666666666662473.0ERCC6
TgeneRIF1chr9:91934712chr2:152315324ENST0000042828723352170_2446951.66666666666662447.0ERCC6
TgeneRIF1chr9:91934712chr2:152315324ENST0000043032822342170_2446951.66666666666662447.0ERCC6
TgeneRIF1chr9:91934712chr2:152315324ENST0000044474623362170_2446951.66666666666662473.0ERCC6
TgeneRIF1chr9:91934712chr2:152315324ENST0000045309123352170_2446951.66666666666662447.0ERCC6


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SECISBP2-RIF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SECISBP2-RIF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource