FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:SEMA3F-RBM6 (FusionGDB2 ID:80297)

Fusion Gene Summary for SEMA3F-RBM6

check button Fusion gene summary
Fusion gene informationFusion gene name: SEMA3F-RBM6
Fusion gene ID: 80297
HgeneTgene
Gene symbol

SEMA3F

RBM6

Gene ID

6405

10180

Gene namesemaphorin 3FRNA binding motif protein 6
SynonymsSEMA-IV|SEMA4|SEMAK3G2|DEF-3|DEF3|HLC-11|NY-LU-12|g16
Cytomap

3p21.31

3p21.31

Type of geneprotein-codingprotein-coding
Descriptionsemaphorin-3Fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, 3Fsemaphorin III/Fsemaphorin IVRNA-binding protein 6RNA-binding protein DEF-3lung cancer antigen NY-LU-12lung cancer protooncogene 11
Modification date2020032220200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000002829, ENST00000413852, 
ENST00000434342, 		ENST00000422955, 
ENST00000441115, ENST00000266022, 
ENST00000442092, ENST00000443081, 
ENST00000539992, ENST00000421682, 
Fusion gene scores* DoF score6 X 9 X 6=32422 X 21 X 10=4620
# samples 1230
** MAII scorelog2(12/324*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(30/4620*10)=-3.94485844580754
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SEMA3F [Title/Abstract] AND RBM6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSEMA3F(50212621)-RBM6(50085678), # samples:2
SEMA3F(50197167)-RBM6(50085678), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSEMA3F

GO:0007411

axon guidance

15814794


check buttonFusion gene breakpoints across SEMA3F (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RBM6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-55-6969-01ASEMA3Fchr3

50211783

+RBM6chr3

50085678

+
ChimerDB4LUADTCGA-55-6969-01ASEMA3Fchr3

50212621

-RBM6chr3

50085678

+
ChimerDB4LUADTCGA-55-6969-01ASEMA3Fchr3

50212621

+RBM6chr3

50085678

+
ChimerDB4LUADTCGA-55-6969-01ASEMA3Fchr3

50214294

+RBM6chr3

50036873

+
ChimerDB4LUADTCGA-55-6969-01ASEMA3Fchr3

50214294

+RBM6chr3

50085678

+
ChimerDB4LUADTCGA-55-6969SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
ChimerDB4LUSCTCGA-37-4135-01ASEMA3Fchr3

50197167

-RBM6chr3

50085678

+
ChimerDB4LUSCTCGA-37-4135SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
ChimerDB4LUSCTCGA-37-4135SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
ChimerDB4OVTCGA-13-1511-01ASEMA3Fchr3

50197167

+RBM6chr3

50000009

+
ChimerDB4OVTCGA-13-1511SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
ChimerDB4UCSTCGA-N5-A4RO-01ASEMA3Fchr3

50214294

-RBM6chr3

50095161

+


Top

Fusion Gene ORF analysis for SEMA3F-RBM6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000002829ENST00000422955SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-3UTRENST00000002829ENST00000441115SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-3UTRENST00000002829ENST00000441115SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
5CDS-3UTRENST00000002829ENST00000441115SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-3UTRENST00000002829ENST00000441115SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-3UTRENST00000002829ENST00000441115SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-3UTRENST00000002829ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-3UTRENST00000002829ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-3UTRENST00000002829ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-3UTRENST00000002829ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-3UTRENST00000002829ENST00000441115SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-3UTRENST00000413852ENST00000422955SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-3UTRENST00000413852ENST00000441115SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-3UTRENST00000413852ENST00000441115SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-3UTRENST00000413852ENST00000441115SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-3UTRENST00000413852ENST00000441115SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-3UTRENST00000413852ENST00000441115SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-3UTRENST00000434342ENST00000422955SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-3UTRENST00000434342ENST00000441115SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-3UTRENST00000434342ENST00000441115SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-3UTRENST00000434342ENST00000441115SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-3UTRENST00000434342ENST00000441115SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-3UTRENST00000434342ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-3UTRENST00000434342ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-3UTRENST00000434342ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-3UTRENST00000434342ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-3UTRENST00000434342ENST00000441115SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-5UTRENST00000002829ENST00000266022SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000266022SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000266022SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000266022SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000002829ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-5UTRENST00000002829ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-5UTRENST00000002829ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-5UTRENST00000002829ENST00000422955SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000422955SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000422955SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000422955SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000002829ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-5UTRENST00000002829ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-5UTRENST00000002829ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-5UTRENST00000002829ENST00000442092SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000442092SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000442092SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000442092SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000002829ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-5UTRENST00000002829ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-5UTRENST00000002829ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-5UTRENST00000002829ENST00000443081SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000443081SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000443081SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000443081SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000002829ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-5UTRENST00000002829ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-5UTRENST00000002829ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-5UTRENST00000002829ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-5UTRENST00000002829ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-5UTRENST00000002829ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-5UTRENST00000002829ENST00000539992SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-5UTRENST00000413852ENST00000266022SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000413852ENST00000266022SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000413852ENST00000266022SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000413852ENST00000422955SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000413852ENST00000422955SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000413852ENST00000422955SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000413852ENST00000442092SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000413852ENST00000442092SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000413852ENST00000442092SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000413852ENST00000443081SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000413852ENST00000443081SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000413852ENST00000443081SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000413852ENST00000539992SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-5UTRENST00000434342ENST00000266022SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000266022SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000266022SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000434342ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-5UTRENST00000434342ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-5UTRENST00000434342ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-5UTRENST00000434342ENST00000422955SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000422955SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000422955SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000434342ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-5UTRENST00000434342ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-5UTRENST00000434342ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-5UTRENST00000434342ENST00000442092SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000442092SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000442092SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000434342ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-5UTRENST00000434342ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-5UTRENST00000434342ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-5UTRENST00000434342ENST00000443081SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000443081SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000443081SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-5UTRENST00000434342ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-5UTRENST00000434342ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-5UTRENST00000434342ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-5UTRENST00000434342ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-5UTRENST00000434342ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-5UTRENST00000434342ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-5UTRENST00000434342ENST00000539992SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-intronENST00000002829ENST00000266022SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000002829ENST00000421682SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-intronENST00000002829ENST00000421682SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
5CDS-intronENST00000002829ENST00000421682SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000002829ENST00000421682SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-intronENST00000002829ENST00000421682SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-intronENST00000002829ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-intronENST00000002829ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-intronENST00000002829ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-intronENST00000002829ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-intronENST00000002829ENST00000421682SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-intronENST00000002829ENST00000422955SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000002829ENST00000442092SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000002829ENST00000443081SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000002829ENST00000539992SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-intronENST00000002829ENST00000539992SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
5CDS-intronENST00000002829ENST00000539992SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000002829ENST00000539992SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-intronENST00000002829ENST00000539992SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-intronENST00000002829ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-intronENST00000002829ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-intronENST00000413852ENST00000266022SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000413852ENST00000421682SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-intronENST00000413852ENST00000421682SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000413852ENST00000421682SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-intronENST00000413852ENST00000421682SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-intronENST00000413852ENST00000421682SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-intronENST00000413852ENST00000422955SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000413852ENST00000442092SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000413852ENST00000443081SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000413852ENST00000539992SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-intronENST00000413852ENST00000539992SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000413852ENST00000539992SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-intronENST00000413852ENST00000539992SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-intronENST00000434342ENST00000266022SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000434342ENST00000421682SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-intronENST00000434342ENST00000421682SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000434342ENST00000421682SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-intronENST00000434342ENST00000421682SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-intronENST00000434342ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-intronENST00000434342ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5CDS-intronENST00000434342ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5CDS-intronENST00000434342ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5CDS-intronENST00000434342ENST00000421682SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
5CDS-intronENST00000434342ENST00000422955SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000434342ENST00000442092SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000434342ENST00000443081SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000434342ENST00000539992SEMA3Fchr3

50211783

+RBM6chr3

50085678

+
5CDS-intronENST00000434342ENST00000539992SEMA3Fchr3

50214294

+RBM6chr3

50036873

+
5CDS-intronENST00000434342ENST00000539992SEMA3Fchr3

50214294

+RBM6chr3

50085678

+
5CDS-intronENST00000434342ENST00000539992SEMA3Fchr3

50211783

+RBM6chr3

50085677

+
5CDS-intronENST00000434342ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5CDS-intronENST00000434342ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5UTR-3UTRENST00000413852ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5UTR-3UTRENST00000413852ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5UTR-3UTRENST00000413852ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5UTR-3UTRENST00000413852ENST00000441115SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5UTR-5UTRENST00000413852ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5UTR-5UTRENST00000413852ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5UTR-5UTRENST00000413852ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5UTR-5UTRENST00000413852ENST00000266022SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5UTR-5UTRENST00000413852ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5UTR-5UTRENST00000413852ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5UTR-5UTRENST00000413852ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5UTR-5UTRENST00000413852ENST00000422955SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5UTR-5UTRENST00000413852ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5UTR-5UTRENST00000413852ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5UTR-5UTRENST00000413852ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5UTR-5UTRENST00000413852ENST00000442092SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5UTR-5UTRENST00000413852ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5UTR-5UTRENST00000413852ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5UTR-5UTRENST00000413852ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5UTR-5UTRENST00000413852ENST00000443081SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5UTR-5UTRENST00000413852ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5UTR-5UTRENST00000413852ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5UTR-intronENST00000413852ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5UTR-intronENST00000413852ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
5UTR-intronENST00000413852ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50000009

+
5UTR-intronENST00000413852ENST00000421682SEMA3Fchr3

50197167

+RBM6chr3

50000008

+
5UTR-intronENST00000413852ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50085677

+
5UTR-intronENST00000413852ENST00000539992SEMA3Fchr3

50197167

+RBM6chr3

50085678

+
In-frameENST00000002829ENST00000266022SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
In-frameENST00000002829ENST00000442092SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
In-frameENST00000002829ENST00000443081SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
In-frameENST00000413852ENST00000266022SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
In-frameENST00000413852ENST00000442092SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
In-frameENST00000413852ENST00000443081SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
In-frameENST00000434342ENST00000266022SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
In-frameENST00000434342ENST00000442092SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
In-frameENST00000434342ENST00000443081SEMA3Fchr3

50214294

-RBM6chr3

50095161

+
intron-3UTRENST00000413852ENST00000441115SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-3UTRENST00000434342ENST00000441115SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-5UTRENST00000413852ENST00000266022SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-5UTRENST00000413852ENST00000422955SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-5UTRENST00000413852ENST00000442092SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-5UTRENST00000413852ENST00000443081SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-5UTRENST00000434342ENST00000266022SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-5UTRENST00000434342ENST00000422955SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-5UTRENST00000434342ENST00000442092SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-5UTRENST00000434342ENST00000443081SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-intronENST00000413852ENST00000421682SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-intronENST00000413852ENST00000539992SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-intronENST00000434342ENST00000421682SEMA3Fchr3

50212621

+RBM6chr3

50085678

+
intron-intronENST00000434342ENST00000539992SEMA3Fchr3

50212621

+RBM6chr3

50085678

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000413852SEMA3Fchr350214294-ENST00000442092RBM6chr350095161+23335381022216704
ENST00000413852SEMA3Fchr350214294-ENST00000266022RBM6chr350095161+23345381022216704
ENST00000413852SEMA3Fchr350214294-ENST00000443081RBM6chr350095161+23325381022216704
ENST00000002829SEMA3Fchr350214294-ENST00000442092RBM6chr350095161+292211274842805773
ENST00000002829SEMA3Fchr350214294-ENST00000266022RBM6chr350095161+292311274842805773
ENST00000002829SEMA3Fchr350214294-ENST00000443081RBM6chr350095161+292111274842805773
ENST00000434342SEMA3Fchr350214294-ENST00000442092RBM6chr350095161+26638683182546742
ENST00000434342SEMA3Fchr350214294-ENST00000266022RBM6chr350095161+26648683182546742
ENST00000434342SEMA3Fchr350214294-ENST00000443081RBM6chr350095161+26628683182546742

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000413852ENST00000442092SEMA3Fchr350214294-RBM6chr350095161+0.0051912910.9948087
ENST00000413852ENST00000266022SEMA3Fchr350214294-RBM6chr350095161+0.0051682650.9948317
ENST00000413852ENST00000443081SEMA3Fchr350214294-RBM6chr350095161+0.0051312650.99486876
ENST00000002829ENST00000442092SEMA3Fchr350214294-RBM6chr350095161+0.0033344790.99666554
ENST00000002829ENST00000266022SEMA3Fchr350214294-RBM6chr350095161+0.0033218510.9966781
ENST00000002829ENST00000443081SEMA3Fchr350214294-RBM6chr350095161+0.0033184990.9966815
ENST00000434342ENST00000442092SEMA3Fchr350214294-RBM6chr350095161+0.0016665430.9983335
ENST00000434342ENST00000266022SEMA3Fchr350214294-RBM6chr350095161+0.0016623470.9983376
ENST00000434342ENST00000443081SEMA3Fchr350214294-RBM6chr350095161+0.0016607580.9983392

Top

Fusion Genomic Features for SEMA3F-RBM6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SEMA3Fchr350197167+RBM6chr350000008+0.302250680.6977494
SEMA3Fchr350197167+RBM6chr350000008+0.302250680.6977494
SEMA3Fchr350197167+RBM6chr350085677+0.0044155290.99558455
SEMA3Fchr350214294+RBM6chr350085677+0.0007313940.9992686
SEMA3Fchr350212621+RBM6chr350085677+0.0003144510.9996855
SEMA3Fchr350214294+RBM6chr350036872+7.98E-050.99992025
SEMA3Fchr350211783+RBM6chr350085677+6.67E-050.99993336
SEMA3Fchr350211783+RBM6chr350085677+6.67E-050.99993336
SEMA3Fchr350197167+RBM6chr350000008+0.302250680.6977494
SEMA3Fchr350197167+RBM6chr350000008+0.302250680.6977494
SEMA3Fchr350197167+RBM6chr350085677+0.0044155290.99558455
SEMA3Fchr350214294+RBM6chr350085677+0.0007313940.9992686
SEMA3Fchr350212621+RBM6chr350085677+0.0003144510.9996855
SEMA3Fchr350214294+RBM6chr350036872+7.98E-050.99992025
SEMA3Fchr350211783+RBM6chr350085677+6.67E-050.99993336
SEMA3Fchr350211783+RBM6chr350085677+6.67E-050.99993336

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for SEMA3F-RBM6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:50212621/chr3:50085678)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRBM6chr3:50214294chr3:50095161ENST00000266022721826_8295641124.0Compositional biasNote=Poly-Glu
TgeneRBM6chr3:50214294chr3:50095161ENST00000266022721892_8955641124.0Compositional biasNote=Poly-Pro
TgeneRBM6chr3:50214294chr3:50095161ENST00000266022721915_9215641124.0Compositional biasNote=Poly-Glu
TgeneRBM6chr3:50214294chr3:50095161ENST00000422955519826_82942602.0Compositional biasNote=Poly-Glu
TgeneRBM6chr3:50214294chr3:50095161ENST00000422955519892_89542602.0Compositional biasNote=Poly-Pro
TgeneRBM6chr3:50214294chr3:50095161ENST00000422955519915_92142602.0Compositional biasNote=Poly-Glu
TgeneRBM6chr3:50214294chr3:50095161ENST00000442092317826_82942602.0Compositional biasNote=Poly-Glu
TgeneRBM6chr3:50214294chr3:50095161ENST00000442092317892_89542602.0Compositional biasNote=Poly-Pro
TgeneRBM6chr3:50214294chr3:50095161ENST00000442092317915_92142602.0Compositional biasNote=Poly-Glu
TgeneRBM6chr3:50214294chr3:50095161ENST000002660227211051_10975641124.0DomainG-patch
TgeneRBM6chr3:50214294chr3:50095161ENST000004229555191051_109742602.0DomainG-patch
TgeneRBM6chr3:50214294chr3:50095161ENST00000422955519456_53642602.0DomainRRM
TgeneRBM6chr3:50214294chr3:50095161ENST000004420923171051_109742602.0DomainG-patch
TgeneRBM6chr3:50214294chr3:50095161ENST00000442092317456_53642602.0DomainRRM

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSEMA3Fchr3:50214294chr3:50095161ENST00000002829-719758_779214786.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneSEMA3Fchr3:50214294chr3:50095161ENST00000434342-618758_779183755.0Compositional biasNote=Arg/Lys-rich (basic)
HgeneSEMA3Fchr3:50214294chr3:50095161ENST00000002829-71931_545214786.0DomainSema
HgeneSEMA3Fchr3:50214294chr3:50095161ENST00000002829-719605_690214786.0DomainNote=Ig-like C2-type
HgeneSEMA3Fchr3:50214294chr3:50095161ENST00000434342-61831_545183755.0DomainSema
HgeneSEMA3Fchr3:50214294chr3:50095161ENST00000434342-618605_690183755.0DomainNote=Ig-like C2-type
TgeneRBM6chr3:50214294chr3:50095161ENST00000266022721456_5365641124.0DomainRRM


Top

Fusion Gene Sequence for SEMA3F-RBM6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80297_80297_1_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000002829_RBM6_chr3_50095161_ENST00000266022_length(transcript)=2923nt_BP=1127nt
AGCGCAGCGCAGGACCTGGGTACGCCGCGAGGAACCGTGCAGCCCAGCGCGGCCGCCCGGCCCGGGTCCAGCAGCCAGGAGAGCGCAGCG
CTTCGAAGCCGAGTGCGCGCCACCGCCCGCGCCCCGCGCTGGGGAATGCGCCCTCGGCGCGCCGGCCAGGGGGCGCCCGCAGCCCACCCC
AGGGGAGGCGGCCCCGAGCGCCCCTGAGCCTTCCCATGGCCCGGGCTGGGGCCCGGGCCCTCGGCTGCTGACGCGCCCGAAGCCCGCGGA
ACCGGTTAAGCCGCGGCCGCGGCGCCGATCCCGGCTGAGGCGCAGCGGCGAGAGGTCGCGGGCAGGGCCATGGCCCCGGGGGGCCGCTAG
CGCGGACCGGCCCAACGGGAGCCGCTCCGTGCCGCCGCCGCCGCCCGGGCGCCCAGGCCCCGCCGCTGCGGAAGAGGTTTCTAGAGAGTG
GAGCCTGCTTCCTGGGCCCTAGGCCCCTCCCACAATGCTTGTCGCCGGTCTTCTTCTCTGGGCTTCCCTACTGACCGGGGCCTGGCCATC
CTTCCCCACCCAGGACCACCTCCCGGCCACGCCCCGGGTCCGGCTCTCATTCAAAGAGCTGAAGGCCACAGGCACCGCCCACTTCTTCAA
CTTCCTGCTCAACACAACCGACTACCGAATCTTGCTCAAGGACGAGGACCACGACCGCATGTACGTGGGCAGCAAGGACTACGTGCTGTC
CCTGGACCTGCACGACATCAACCGCGAGCCCCTCATTATACACTGGGCAGCCTCCCCACAGCGCATCGAGGAATGCGTGCTCTCAGGCAA
GGATGTCAACGGCGAGTGTGGGAACTTCGTCAGGCTCATCCAGCCCTGGAACCGAACACACCTGTATGTGTGCGGGACAGGTGCCTACAA
CCCCATGTGCACCTATGTGAACCGCGGACGCCGCGCCCAGGCCACACCATGGACCCAGACTCAGGCGGTCAGAGGCCGCGGCAGCAGAGC
CACGGATGGTGCCCTCCGCCCGATGCCCACAGCCCCACGCCAGGATTACATCTTCTACCTGGAGCCTGAGCGACTCGAGTCAGGGAAGGG
CAAGTGTCCGTACGATCCCAAGCTGGACACAGCATCGGCCCTCATCATGACAGAGGCCAAGCAAGAATTAATAACCTACCCTCAGCCTCA
GAAAACATCCATACCAGCACCATTGGAAAAACAGCCCAACCAGCCCCTAAGACCAGCTGATAAGGAACCTGAACCCAGGAAGAGGGAAGA
AGGCCAAGAGTCACGCTTAGGACATCAAAAGAGAGAAGCAGAAAGGTATCTGCCTCCTTCTCGAAGGGAAGGGCCAACTTTCCGAAGAGA
CCGAGAGAGGGAGTCATGGTCTGGAGAGACACGCCAGGATGGAGAGAGCAAAACTATCATGCTAAAGCGTATCTATCGTTCCACACCACC
TGAGGTGATAGTGGAAGTGCTGGAGCCCTATGTCCGCCTTACTACTGCCAACGTCCGTATCATCAAGAACAGAACAGGCCCTATGGGGCA
TACCTATGGCTTTATTGACCTCGACTCCCATGCGGAAGCTCTTCGTGTGGTGAAGATCTTACAGAACCTTGATCCGCCATTTAGCATTGA
TGGGAAGATGGTAGCTGTAAACCTGGCCACTGGAAAACGAAGAAATGATTCTGGGGACCATTCTGACCACATGCATTACTATCAGGGTAA
AAAATATTTCCGAGATAGGAGGGGAGGTGGCAGAAATTCAGACTGGTCTTCAGATACAAATCGACAAGGACAACAGTCATCATCTGACTG
CTACATATATGATTCTGCTACTGGCTACTATTATGACCCCTTGGCAGGAACTTATTATGACCCCAATACCCAGCAAGAAGTCTATGTGCC
CCAGGATCCTGGATTACCTGAGGAAGAAGAGATCAAGGAAAAAAAACCCACCAGTCAAGGAAAGTCAAGTAGCAAGAAGGAAATGTCTAA
AAGAGATGGCAAGGAGAAAAAAGACAGAGGAGTGACGAGGTTTCAGGAAAATGCCAGTGAAGGGAAGGCCCCTGCAGAAGACGTCTTTAA
GAAGCCCCTGCCTCCTACTGTGAAGAAGGAAGAGAGTCCCCCTCCACCTAAAGTGGTAAACCCACTGATCGGCCTCTTGGGTGAATATGG
AGGAGACAGTGACTATGAGGAGGAAGAAGAGGAGGAACAGACCCCTCCCCCACAGCCCCGCACAGCACAGCCCCAGAAGCGAGAGGAGCA
AACCAAGAAGGAGAATGAAGAAGACAAACTCACTGACTGGAATAAACTGGCTTGTCTGCTTTGCAGAAGGCAGTTTCCCAATAAAGAAGT
TCTGATCAAACACCAGCAGCTGTCAGACCTGCACAAGCAAAACCTGGAAATCCACCGGAAGATAAAACAGTCTGAGCAGGAGCTAGCCTA
TCTGGAAAGGAGAGAACGAGAGGGAAAGTTTAAAGGAAGAGGAAATGATCGCAGGGAAAAGCTCCAGTCTTTTGACTCTCCAGAAAGGAA
ACGGATTAAGTACTCCAGGGAAACTGACAGTGATCGTAAACTTGTTGATAAAGAAGATATCGACACTAGCAGCAAAGGAGGCTGTGTCCA
ACAGGCTACTGGCTGGAGGAAAGGGACAGGCCTGGGATATGGCCATCCTGGATTGGCTTCATCAGAGGAGGCTGAAGGCCGGATGAGGGG
CCCCAGTGTTGGAGCCTCAGGAAGAACCAGCAAAAGACAGTCCAACGAGACTTACCGAGATGCTGTTCGAAGAGTCATGTTTGCTCGATA
TAAAGAACTCGATTAAGAAAGGAGACAAGTTCCATGGGATACAACCTCCCTCTTGTTTTGTTTGTCTCTCCTTTTCTTTTGTTACTGTTC

>80297_80297_1_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000002829_RBM6_chr3_50095161_ENST00000266022_length(amino acids)=773AA_BP=215
MLVAGLLLWASLLTGAWPSFPTQDHLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPL
IIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTA
PRQDYIFYLEPERLESGKGKCPYDPKLDTASALIMTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADKEPEPRKREEGQESRLGHQKR
EAERYLPPSRREGPTFRRDRERESWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHTYGFIDLDSHA
EALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNRQGQQSSSDCYIYDSATGYYY
DPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEE
SPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLH
KQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGL

--------------------------------------------------------------
>80297_80297_2_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000002829_RBM6_chr3_50095161_ENST00000442092_length(transcript)=2922nt_BP=1127nt
AGCGCAGCGCAGGACCTGGGTACGCCGCGAGGAACCGTGCAGCCCAGCGCGGCCGCCCGGCCCGGGTCCAGCAGCCAGGAGAGCGCAGCG
CTTCGAAGCCGAGTGCGCGCCACCGCCCGCGCCCCGCGCTGGGGAATGCGCCCTCGGCGCGCCGGCCAGGGGGCGCCCGCAGCCCACCCC
AGGGGAGGCGGCCCCGAGCGCCCCTGAGCCTTCCCATGGCCCGGGCTGGGGCCCGGGCCCTCGGCTGCTGACGCGCCCGAAGCCCGCGGA
ACCGGTTAAGCCGCGGCCGCGGCGCCGATCCCGGCTGAGGCGCAGCGGCGAGAGGTCGCGGGCAGGGCCATGGCCCCGGGGGGCCGCTAG
CGCGGACCGGCCCAACGGGAGCCGCTCCGTGCCGCCGCCGCCGCCCGGGCGCCCAGGCCCCGCCGCTGCGGAAGAGGTTTCTAGAGAGTG
GAGCCTGCTTCCTGGGCCCTAGGCCCCTCCCACAATGCTTGTCGCCGGTCTTCTTCTCTGGGCTTCCCTACTGACCGGGGCCTGGCCATC
CTTCCCCACCCAGGACCACCTCCCGGCCACGCCCCGGGTCCGGCTCTCATTCAAAGAGCTGAAGGCCACAGGCACCGCCCACTTCTTCAA
CTTCCTGCTCAACACAACCGACTACCGAATCTTGCTCAAGGACGAGGACCACGACCGCATGTACGTGGGCAGCAAGGACTACGTGCTGTC
CCTGGACCTGCACGACATCAACCGCGAGCCCCTCATTATACACTGGGCAGCCTCCCCACAGCGCATCGAGGAATGCGTGCTCTCAGGCAA
GGATGTCAACGGCGAGTGTGGGAACTTCGTCAGGCTCATCCAGCCCTGGAACCGAACACACCTGTATGTGTGCGGGACAGGTGCCTACAA
CCCCATGTGCACCTATGTGAACCGCGGACGCCGCGCCCAGGCCACACCATGGACCCAGACTCAGGCGGTCAGAGGCCGCGGCAGCAGAGC
CACGGATGGTGCCCTCCGCCCGATGCCCACAGCCCCACGCCAGGATTACATCTTCTACCTGGAGCCTGAGCGACTCGAGTCAGGGAAGGG
CAAGTGTCCGTACGATCCCAAGCTGGACACAGCATCGGCCCTCATCATGACAGAGGCCAAGCAAGAATTAATAACCTACCCTCAGCCTCA
GAAAACATCCATACCAGCACCATTGGAAAAACAGCCCAACCAGCCCCTAAGACCAGCTGATAAGGAACCTGAACCCAGGAAGAGGGAAGA
AGGCCAAGAGTCACGCTTAGGACATCAAAAGAGAGAAGCAGAAAGGTATCTGCCTCCTTCTCGAAGGGAAGGGCCAACTTTCCGAAGAGA
CCGAGAGAGGGAGTCATGGTCTGGAGAGACACGCCAGGATGGAGAGAGCAAAACTATCATGCTAAAGCGTATCTATCGTTCCACACCACC
TGAGGTGATAGTGGAAGTGCTGGAGCCCTATGTCCGCCTTACTACTGCCAACGTCCGTATCATCAAGAACAGAACAGGCCCTATGGGGCA
TACCTATGGCTTTATTGACCTCGACTCCCATGCGGAAGCTCTTCGTGTGGTGAAGATCTTACAGAACCTTGATCCGCCATTTAGCATTGA
TGGGAAGATGGTAGCTGTAAACCTGGCCACTGGAAAACGAAGAAATGATTCTGGGGACCATTCTGACCACATGCATTACTATCAGGGTAA
AAAATATTTCCGAGATAGGAGGGGAGGTGGCAGAAATTCAGACTGGTCTTCAGATACAAATCGACAAGGACAACAGTCATCATCTGACTG
CTACATATATGATTCTGCTACTGGCTACTATTATGACCCCTTGGCAGGAACTTATTATGACCCCAATACCCAGCAAGAAGTCTATGTGCC
CCAGGATCCTGGATTACCTGAGGAAGAAGAGATCAAGGAAAAAAAACCCACCAGTCAAGGAAAGTCAAGTAGCAAGAAGGAAATGTCTAA
AAGAGATGGCAAGGAGAAAAAAGACAGAGGAGTGACGAGGTTTCAGGAAAATGCCAGTGAAGGGAAGGCCCCTGCAGAAGACGTCTTTAA
GAAGCCCCTGCCTCCTACTGTGAAGAAGGAAGAGAGTCCCCCTCCACCTAAAGTGGTAAACCCACTGATCGGCCTCTTGGGTGAATATGG
AGGAGACAGTGACTATGAGGAGGAAGAAGAGGAGGAACAGACCCCTCCCCCACAGCCCCGCACAGCACAGCCCCAGAAGCGAGAGGAGCA
AACCAAGAAGGAGAATGAAGAAGACAAACTCACTGACTGGAATAAACTGGCTTGTCTGCTTTGCAGAAGGCAGTTTCCCAATAAAGAAGT
TCTGATCAAACACCAGCAGCTGTCAGACCTGCACAAGCAAAACCTGGAAATCCACCGGAAGATAAAACAGTCTGAGCAGGAGCTAGCCTA
TCTGGAAAGGAGAGAACGAGAGGGAAAGTTTAAAGGAAGAGGAAATGATCGCAGGGAAAAGCTCCAGTCTTTTGACTCTCCAGAAAGGAA
ACGGATTAAGTACTCCAGGGAAACTGACAGTGATCGTAAACTTGTTGATAAAGAAGATATCGACACTAGCAGCAAAGGAGGCTGTGTCCA
ACAGGCTACTGGCTGGAGGAAAGGGACAGGCCTGGGATATGGCCATCCTGGATTGGCTTCATCAGAGGAGGCTGAAGGCCGGATGAGGGG
CCCCAGTGTTGGAGCCTCAGGAAGAACCAGCAAAAGACAGTCCAACGAGACTTACCGAGATGCTGTTCGAAGAGTCATGTTTGCTCGATA
TAAAGAACTCGATTAAGAAAGGAGACAAGTTCCATGGGATACAACCTCCCTCTTGTTTTGTTTGTCTCTCCTTTTCTTTTGTTACTGTTC

>80297_80297_2_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000002829_RBM6_chr3_50095161_ENST00000442092_length(amino acids)=773AA_BP=215
MLVAGLLLWASLLTGAWPSFPTQDHLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPL
IIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTA
PRQDYIFYLEPERLESGKGKCPYDPKLDTASALIMTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADKEPEPRKREEGQESRLGHQKR
EAERYLPPSRREGPTFRRDRERESWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHTYGFIDLDSHA
EALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNRQGQQSSSDCYIYDSATGYYY
DPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEE
SPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLH
KQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGL

--------------------------------------------------------------
>80297_80297_3_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000002829_RBM6_chr3_50095161_ENST00000443081_length(transcript)=2921nt_BP=1127nt
AGCGCAGCGCAGGACCTGGGTACGCCGCGAGGAACCGTGCAGCCCAGCGCGGCCGCCCGGCCCGGGTCCAGCAGCCAGGAGAGCGCAGCG
CTTCGAAGCCGAGTGCGCGCCACCGCCCGCGCCCCGCGCTGGGGAATGCGCCCTCGGCGCGCCGGCCAGGGGGCGCCCGCAGCCCACCCC
AGGGGAGGCGGCCCCGAGCGCCCCTGAGCCTTCCCATGGCCCGGGCTGGGGCCCGGGCCCTCGGCTGCTGACGCGCCCGAAGCCCGCGGA
ACCGGTTAAGCCGCGGCCGCGGCGCCGATCCCGGCTGAGGCGCAGCGGCGAGAGGTCGCGGGCAGGGCCATGGCCCCGGGGGGCCGCTAG
CGCGGACCGGCCCAACGGGAGCCGCTCCGTGCCGCCGCCGCCGCCCGGGCGCCCAGGCCCCGCCGCTGCGGAAGAGGTTTCTAGAGAGTG
GAGCCTGCTTCCTGGGCCCTAGGCCCCTCCCACAATGCTTGTCGCCGGTCTTCTTCTCTGGGCTTCCCTACTGACCGGGGCCTGGCCATC
CTTCCCCACCCAGGACCACCTCCCGGCCACGCCCCGGGTCCGGCTCTCATTCAAAGAGCTGAAGGCCACAGGCACCGCCCACTTCTTCAA
CTTCCTGCTCAACACAACCGACTACCGAATCTTGCTCAAGGACGAGGACCACGACCGCATGTACGTGGGCAGCAAGGACTACGTGCTGTC
CCTGGACCTGCACGACATCAACCGCGAGCCCCTCATTATACACTGGGCAGCCTCCCCACAGCGCATCGAGGAATGCGTGCTCTCAGGCAA
GGATGTCAACGGCGAGTGTGGGAACTTCGTCAGGCTCATCCAGCCCTGGAACCGAACACACCTGTATGTGTGCGGGACAGGTGCCTACAA
CCCCATGTGCACCTATGTGAACCGCGGACGCCGCGCCCAGGCCACACCATGGACCCAGACTCAGGCGGTCAGAGGCCGCGGCAGCAGAGC
CACGGATGGTGCCCTCCGCCCGATGCCCACAGCCCCACGCCAGGATTACATCTTCTACCTGGAGCCTGAGCGACTCGAGTCAGGGAAGGG
CAAGTGTCCGTACGATCCCAAGCTGGACACAGCATCGGCCCTCATCATGACAGAGGCCAAGCAAGAATTAATAACCTACCCTCAGCCTCA
GAAAACATCCATACCAGCACCATTGGAAAAACAGCCCAACCAGCCCCTAAGACCAGCTGATAAGGAACCTGAACCCAGGAAGAGGGAAGA
AGGCCAAGAGTCACGCTTAGGACATCAAAAGAGAGAAGCAGAAAGGTATCTGCCTCCTTCTCGAAGGGAAGGGCCAACTTTCCGAAGAGA
CCGAGAGAGGGAGTCATGGTCTGGAGAGACACGCCAGGATGGAGAGAGCAAAACTATCATGCTAAAGCGTATCTATCGTTCCACACCACC
TGAGGTGATAGTGGAAGTGCTGGAGCCCTATGTCCGCCTTACTACTGCCAACGTCCGTATCATCAAGAACAGAACAGGCCCTATGGGGCA
TACCTATGGCTTTATTGACCTCGACTCCCATGCGGAAGCTCTTCGTGTGGTGAAGATCTTACAGAACCTTGATCCGCCATTTAGCATTGA
TGGGAAGATGGTAGCTGTAAACCTGGCCACTGGAAAACGAAGAAATGATTCTGGGGACCATTCTGACCACATGCATTACTATCAGGGTAA
AAAATATTTCCGAGATAGGAGGGGAGGTGGCAGAAATTCAGACTGGTCTTCAGATACAAATCGACAAGGACAACAGTCATCATCTGACTG
CTACATATATGATTCTGCTACTGGCTACTATTATGACCCCTTGGCAGGAACTTATTATGACCCCAATACCCAGCAAGAAGTCTATGTGCC
CCAGGATCCTGGATTACCTGAGGAAGAAGAGATCAAGGAAAAAAAACCCACCAGTCAAGGAAAGTCAAGTAGCAAGAAGGAAATGTCTAA
AAGAGATGGCAAGGAGAAAAAAGACAGAGGAGTGACGAGGTTTCAGGAAAATGCCAGTGAAGGGAAGGCCCCTGCAGAAGACGTCTTTAA
GAAGCCCCTGCCTCCTACTGTGAAGAAGGAAGAGAGTCCCCCTCCACCTAAAGTGGTAAACCCACTGATCGGCCTCTTGGGTGAATATGG
AGGAGACAGTGACTATGAGGAGGAAGAAGAGGAGGAACAGACCCCTCCCCCACAGCCCCGCACAGCACAGCCCCAGAAGCGAGAGGAGCA
AACCAAGAAGGAGAATGAAGAAGACAAACTCACTGACTGGAATAAACTGGCTTGTCTGCTTTGCAGAAGGCAGTTTCCCAATAAAGAAGT
TCTGATCAAACACCAGCAGCTGTCAGACCTGCACAAGCAAAACCTGGAAATCCACCGGAAGATAAAACAGTCTGAGCAGGAGCTAGCCTA
TCTGGAAAGGAGAGAACGAGAGGGAAAGTTTAAAGGAAGAGGAAATGATCGCAGGGAAAAGCTCCAGTCTTTTGACTCTCCAGAAAGGAA
ACGGATTAAGTACTCCAGGGAAACTGACAGTGATCGTAAACTTGTTGATAAAGAAGATATCGACACTAGCAGCAAAGGAGGCTGTGTCCA
ACAGGCTACTGGCTGGAGGAAAGGGACAGGCCTGGGATATGGCCATCCTGGATTGGCTTCATCAGAGGAGGCTGAAGGCCGGATGAGGGG
CCCCAGTGTTGGAGCCTCAGGAAGAACCAGCAAAAGACAGTCCAACGAGACTTACCGAGATGCTGTTCGAAGAGTCATGTTTGCTCGATA
TAAAGAACTCGATTAAGAAAGGAGACAAGTTCCATGGGATACAACCTCCCTCTTGTTTTGTTTGTCTCTCCTTTTCTTTTGTTACTGTTC

>80297_80297_3_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000002829_RBM6_chr3_50095161_ENST00000443081_length(amino acids)=773AA_BP=215
MLVAGLLLWASLLTGAWPSFPTQDHLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPL
IIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTA
PRQDYIFYLEPERLESGKGKCPYDPKLDTASALIMTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADKEPEPRKREEGQESRLGHQKR
EAERYLPPSRREGPTFRRDRERESWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHTYGFIDLDSHA
EALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNRQGQQSSSDCYIYDSATGYYY
DPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEE
SPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLH
KQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGL

--------------------------------------------------------------
>80297_80297_4_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000413852_RBM6_chr3_50095161_ENST00000266022_length(transcript)=2334nt_BP=538nt
GAGCGAGCGAACGAACCGCGGCGGTCCGGAGAGCCCCGAGCGCAGCGCAGGACCTGGGACCACCTCCCGGCCACGCCCCGGGTCCGGCTC
TCATTCAAAGAGCTGAAGGCCACAGGCACCGCCCACTTCTTCAACTTCCTGCTCAACACAACCGACTACCGAATCTTGCTCAAGGACGAG
GACCACGACCGCATGTACGTGGGCAGCAAGGACTACGTGCTGTCCCTGGACCTGCACGACATCAACCGCGAGCCCCTCATTATACACTGG
GCAGCCTCCCCACAGCGCATCGAGGAATGCGTGCTCTCAGGCAAGGATGTCAACGGCGAGTGTGGGAACTTCGTCAGGCTCATCCAGCCC
TGGAACCGAACACACCTGTATGTGTGCGGGACAGGTGCCTACAACCCCATGTGCACCTATGTGAACCGCGGACGCCGCGCCCAGGATTAC
ATCTTCTACCTGGAGCCTGAGCGACTCGAGTCAGGGAAGGGCAAGTGTCCGTACGATCCCAAGCTGGACACAGCATCGGCCCTCATCATG
ACAGAGGCCAAGCAAGAATTAATAACCTACCCTCAGCCTCAGAAAACATCCATACCAGCACCATTGGAAAAACAGCCCAACCAGCCCCTA
AGACCAGCTGATAAGGAACCTGAACCCAGGAAGAGGGAAGAAGGCCAAGAGTCACGCTTAGGACATCAAAAGAGAGAAGCAGAAAGGTAT
CTGCCTCCTTCTCGAAGGGAAGGGCCAACTTTCCGAAGAGACCGAGAGAGGGAGTCATGGTCTGGAGAGACACGCCAGGATGGAGAGAGC
AAAACTATCATGCTAAAGCGTATCTATCGTTCCACACCACCTGAGGTGATAGTGGAAGTGCTGGAGCCCTATGTCCGCCTTACTACTGCC
AACGTCCGTATCATCAAGAACAGAACAGGCCCTATGGGGCATACCTATGGCTTTATTGACCTCGACTCCCATGCGGAAGCTCTTCGTGTG
GTGAAGATCTTACAGAACCTTGATCCGCCATTTAGCATTGATGGGAAGATGGTAGCTGTAAACCTGGCCACTGGAAAACGAAGAAATGAT
TCTGGGGACCATTCTGACCACATGCATTACTATCAGGGTAAAAAATATTTCCGAGATAGGAGGGGAGGTGGCAGAAATTCAGACTGGTCT
TCAGATACAAATCGACAAGGACAACAGTCATCATCTGACTGCTACATATATGATTCTGCTACTGGCTACTATTATGACCCCTTGGCAGGA
ACTTATTATGACCCCAATACCCAGCAAGAAGTCTATGTGCCCCAGGATCCTGGATTACCTGAGGAAGAAGAGATCAAGGAAAAAAAACCC
ACCAGTCAAGGAAAGTCAAGTAGCAAGAAGGAAATGTCTAAAAGAGATGGCAAGGAGAAAAAAGACAGAGGAGTGACGAGGTTTCAGGAA
AATGCCAGTGAAGGGAAGGCCCCTGCAGAAGACGTCTTTAAGAAGCCCCTGCCTCCTACTGTGAAGAAGGAAGAGAGTCCCCCTCCACCT
AAAGTGGTAAACCCACTGATCGGCCTCTTGGGTGAATATGGAGGAGACAGTGACTATGAGGAGGAAGAAGAGGAGGAACAGACCCCTCCC
CCACAGCCCCGCACAGCACAGCCCCAGAAGCGAGAGGAGCAAACCAAGAAGGAGAATGAAGAAGACAAACTCACTGACTGGAATAAACTG
GCTTGTCTGCTTTGCAGAAGGCAGTTTCCCAATAAAGAAGTTCTGATCAAACACCAGCAGCTGTCAGACCTGCACAAGCAAAACCTGGAA
ATCCACCGGAAGATAAAACAGTCTGAGCAGGAGCTAGCCTATCTGGAAAGGAGAGAACGAGAGGGAAAGTTTAAAGGAAGAGGAAATGAT
CGCAGGGAAAAGCTCCAGTCTTTTGACTCTCCAGAAAGGAAACGGATTAAGTACTCCAGGGAAACTGACAGTGATCGTAAACTTGTTGAT
AAAGAAGATATCGACACTAGCAGCAAAGGAGGCTGTGTCCAACAGGCTACTGGCTGGAGGAAAGGGACAGGCCTGGGATATGGCCATCCT
GGATTGGCTTCATCAGAGGAGGCTGAAGGCCGGATGAGGGGCCCCAGTGTTGGAGCCTCAGGAAGAACCAGCAAAAGACAGTCCAACGAG
ACTTACCGAGATGCTGTTCGAAGAGTCATGTTTGCTCGATATAAAGAACTCGATTAAGAAAGGAGACAAGTTCCATGGGATACAACCTCC

>80297_80297_4_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000413852_RBM6_chr3_50095161_ENST00000266022_length(amino acids)=704AA_BP=146
MKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPLIIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRT
HLYVCGTGAYNPMCTYVNRGRRAQDYIFYLEPERLESGKGKCPYDPKLDTASALIMTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPAD
KEPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRI
IKNRTGPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTN
RQGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASE
GKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLL
CRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDI

--------------------------------------------------------------
>80297_80297_5_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000413852_RBM6_chr3_50095161_ENST00000442092_length(transcript)=2333nt_BP=538nt
GAGCGAGCGAACGAACCGCGGCGGTCCGGAGAGCCCCGAGCGCAGCGCAGGACCTGGGACCACCTCCCGGCCACGCCCCGGGTCCGGCTC
TCATTCAAAGAGCTGAAGGCCACAGGCACCGCCCACTTCTTCAACTTCCTGCTCAACACAACCGACTACCGAATCTTGCTCAAGGACGAG
GACCACGACCGCATGTACGTGGGCAGCAAGGACTACGTGCTGTCCCTGGACCTGCACGACATCAACCGCGAGCCCCTCATTATACACTGG
GCAGCCTCCCCACAGCGCATCGAGGAATGCGTGCTCTCAGGCAAGGATGTCAACGGCGAGTGTGGGAACTTCGTCAGGCTCATCCAGCCC
TGGAACCGAACACACCTGTATGTGTGCGGGACAGGTGCCTACAACCCCATGTGCACCTATGTGAACCGCGGACGCCGCGCCCAGGATTAC
ATCTTCTACCTGGAGCCTGAGCGACTCGAGTCAGGGAAGGGCAAGTGTCCGTACGATCCCAAGCTGGACACAGCATCGGCCCTCATCATG
ACAGAGGCCAAGCAAGAATTAATAACCTACCCTCAGCCTCAGAAAACATCCATACCAGCACCATTGGAAAAACAGCCCAACCAGCCCCTA
AGACCAGCTGATAAGGAACCTGAACCCAGGAAGAGGGAAGAAGGCCAAGAGTCACGCTTAGGACATCAAAAGAGAGAAGCAGAAAGGTAT
CTGCCTCCTTCTCGAAGGGAAGGGCCAACTTTCCGAAGAGACCGAGAGAGGGAGTCATGGTCTGGAGAGACACGCCAGGATGGAGAGAGC
AAAACTATCATGCTAAAGCGTATCTATCGTTCCACACCACCTGAGGTGATAGTGGAAGTGCTGGAGCCCTATGTCCGCCTTACTACTGCC
AACGTCCGTATCATCAAGAACAGAACAGGCCCTATGGGGCATACCTATGGCTTTATTGACCTCGACTCCCATGCGGAAGCTCTTCGTGTG
GTGAAGATCTTACAGAACCTTGATCCGCCATTTAGCATTGATGGGAAGATGGTAGCTGTAAACCTGGCCACTGGAAAACGAAGAAATGAT
TCTGGGGACCATTCTGACCACATGCATTACTATCAGGGTAAAAAATATTTCCGAGATAGGAGGGGAGGTGGCAGAAATTCAGACTGGTCT
TCAGATACAAATCGACAAGGACAACAGTCATCATCTGACTGCTACATATATGATTCTGCTACTGGCTACTATTATGACCCCTTGGCAGGA
ACTTATTATGACCCCAATACCCAGCAAGAAGTCTATGTGCCCCAGGATCCTGGATTACCTGAGGAAGAAGAGATCAAGGAAAAAAAACCC
ACCAGTCAAGGAAAGTCAAGTAGCAAGAAGGAAATGTCTAAAAGAGATGGCAAGGAGAAAAAAGACAGAGGAGTGACGAGGTTTCAGGAA
AATGCCAGTGAAGGGAAGGCCCCTGCAGAAGACGTCTTTAAGAAGCCCCTGCCTCCTACTGTGAAGAAGGAAGAGAGTCCCCCTCCACCT
AAAGTGGTAAACCCACTGATCGGCCTCTTGGGTGAATATGGAGGAGACAGTGACTATGAGGAGGAAGAAGAGGAGGAACAGACCCCTCCC
CCACAGCCCCGCACAGCACAGCCCCAGAAGCGAGAGGAGCAAACCAAGAAGGAGAATGAAGAAGACAAACTCACTGACTGGAATAAACTG
GCTTGTCTGCTTTGCAGAAGGCAGTTTCCCAATAAAGAAGTTCTGATCAAACACCAGCAGCTGTCAGACCTGCACAAGCAAAACCTGGAA
ATCCACCGGAAGATAAAACAGTCTGAGCAGGAGCTAGCCTATCTGGAAAGGAGAGAACGAGAGGGAAAGTTTAAAGGAAGAGGAAATGAT
CGCAGGGAAAAGCTCCAGTCTTTTGACTCTCCAGAAAGGAAACGGATTAAGTACTCCAGGGAAACTGACAGTGATCGTAAACTTGTTGAT
AAAGAAGATATCGACACTAGCAGCAAAGGAGGCTGTGTCCAACAGGCTACTGGCTGGAGGAAAGGGACAGGCCTGGGATATGGCCATCCT
GGATTGGCTTCATCAGAGGAGGCTGAAGGCCGGATGAGGGGCCCCAGTGTTGGAGCCTCAGGAAGAACCAGCAAAAGACAGTCCAACGAG
ACTTACCGAGATGCTGTTCGAAGAGTCATGTTTGCTCGATATAAAGAACTCGATTAAGAAAGGAGACAAGTTCCATGGGATACAACCTCC

>80297_80297_5_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000413852_RBM6_chr3_50095161_ENST00000442092_length(amino acids)=704AA_BP=146
MKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPLIIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRT
HLYVCGTGAYNPMCTYVNRGRRAQDYIFYLEPERLESGKGKCPYDPKLDTASALIMTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPAD
KEPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRI
IKNRTGPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTN
RQGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASE
GKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLL
CRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDI

--------------------------------------------------------------
>80297_80297_6_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000413852_RBM6_chr3_50095161_ENST00000443081_length(transcript)=2332nt_BP=538nt
GAGCGAGCGAACGAACCGCGGCGGTCCGGAGAGCCCCGAGCGCAGCGCAGGACCTGGGACCACCTCCCGGCCACGCCCCGGGTCCGGCTC
TCATTCAAAGAGCTGAAGGCCACAGGCACCGCCCACTTCTTCAACTTCCTGCTCAACACAACCGACTACCGAATCTTGCTCAAGGACGAG
GACCACGACCGCATGTACGTGGGCAGCAAGGACTACGTGCTGTCCCTGGACCTGCACGACATCAACCGCGAGCCCCTCATTATACACTGG
GCAGCCTCCCCACAGCGCATCGAGGAATGCGTGCTCTCAGGCAAGGATGTCAACGGCGAGTGTGGGAACTTCGTCAGGCTCATCCAGCCC
TGGAACCGAACACACCTGTATGTGTGCGGGACAGGTGCCTACAACCCCATGTGCACCTATGTGAACCGCGGACGCCGCGCCCAGGATTAC
ATCTTCTACCTGGAGCCTGAGCGACTCGAGTCAGGGAAGGGCAAGTGTCCGTACGATCCCAAGCTGGACACAGCATCGGCCCTCATCATG
ACAGAGGCCAAGCAAGAATTAATAACCTACCCTCAGCCTCAGAAAACATCCATACCAGCACCATTGGAAAAACAGCCCAACCAGCCCCTA
AGACCAGCTGATAAGGAACCTGAACCCAGGAAGAGGGAAGAAGGCCAAGAGTCACGCTTAGGACATCAAAAGAGAGAAGCAGAAAGGTAT
CTGCCTCCTTCTCGAAGGGAAGGGCCAACTTTCCGAAGAGACCGAGAGAGGGAGTCATGGTCTGGAGAGACACGCCAGGATGGAGAGAGC
AAAACTATCATGCTAAAGCGTATCTATCGTTCCACACCACCTGAGGTGATAGTGGAAGTGCTGGAGCCCTATGTCCGCCTTACTACTGCC
AACGTCCGTATCATCAAGAACAGAACAGGCCCTATGGGGCATACCTATGGCTTTATTGACCTCGACTCCCATGCGGAAGCTCTTCGTGTG
GTGAAGATCTTACAGAACCTTGATCCGCCATTTAGCATTGATGGGAAGATGGTAGCTGTAAACCTGGCCACTGGAAAACGAAGAAATGAT
TCTGGGGACCATTCTGACCACATGCATTACTATCAGGGTAAAAAATATTTCCGAGATAGGAGGGGAGGTGGCAGAAATTCAGACTGGTCT
TCAGATACAAATCGACAAGGACAACAGTCATCATCTGACTGCTACATATATGATTCTGCTACTGGCTACTATTATGACCCCTTGGCAGGA
ACTTATTATGACCCCAATACCCAGCAAGAAGTCTATGTGCCCCAGGATCCTGGATTACCTGAGGAAGAAGAGATCAAGGAAAAAAAACCC
ACCAGTCAAGGAAAGTCAAGTAGCAAGAAGGAAATGTCTAAAAGAGATGGCAAGGAGAAAAAAGACAGAGGAGTGACGAGGTTTCAGGAA
AATGCCAGTGAAGGGAAGGCCCCTGCAGAAGACGTCTTTAAGAAGCCCCTGCCTCCTACTGTGAAGAAGGAAGAGAGTCCCCCTCCACCT
AAAGTGGTAAACCCACTGATCGGCCTCTTGGGTGAATATGGAGGAGACAGTGACTATGAGGAGGAAGAAGAGGAGGAACAGACCCCTCCC
CCACAGCCCCGCACAGCACAGCCCCAGAAGCGAGAGGAGCAAACCAAGAAGGAGAATGAAGAAGACAAACTCACTGACTGGAATAAACTG
GCTTGTCTGCTTTGCAGAAGGCAGTTTCCCAATAAAGAAGTTCTGATCAAACACCAGCAGCTGTCAGACCTGCACAAGCAAAACCTGGAA
ATCCACCGGAAGATAAAACAGTCTGAGCAGGAGCTAGCCTATCTGGAAAGGAGAGAACGAGAGGGAAAGTTTAAAGGAAGAGGAAATGAT
CGCAGGGAAAAGCTCCAGTCTTTTGACTCTCCAGAAAGGAAACGGATTAAGTACTCCAGGGAAACTGACAGTGATCGTAAACTTGTTGAT
AAAGAAGATATCGACACTAGCAGCAAAGGAGGCTGTGTCCAACAGGCTACTGGCTGGAGGAAAGGGACAGGCCTGGGATATGGCCATCCT
GGATTGGCTTCATCAGAGGAGGCTGAAGGCCGGATGAGGGGCCCCAGTGTTGGAGCCTCAGGAAGAACCAGCAAAAGACAGTCCAACGAG
ACTTACCGAGATGCTGTTCGAAGAGTCATGTTTGCTCGATATAAAGAACTCGATTAAGAAAGGAGACAAGTTCCATGGGATACAACCTCC

>80297_80297_6_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000413852_RBM6_chr3_50095161_ENST00000443081_length(amino acids)=704AA_BP=146
MKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPLIIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRT
HLYVCGTGAYNPMCTYVNRGRRAQDYIFYLEPERLESGKGKCPYDPKLDTASALIMTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPAD
KEPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRI
IKNRTGPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTN
RQGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASE
GKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLL
CRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDI

--------------------------------------------------------------
>80297_80297_7_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000434342_RBM6_chr3_50095161_ENST00000266022_length(transcript)=2664nt_BP=868nt
CTGACTGGTGCTCCCTCTCTTCCATCTTGGGCTGTCTGCATGTGTCTCATTCCCCCACTCTCTCCTGTGCCTCCCCTCTACCGTAATAAT
CAGGTCCAGGTTTCTCTGTACTGGGAGAAGACCTGTGGCTGGAGCAGGCAGGGATGCACCCTATCTGTTCCCCATTCCTCCAGGTGGGAG
GGAGAAGGAGTAACCCACTTTATTGGCCACAGATGCAGGGGAGAAAGGAGAAAGCATGCTGGGAGCTGGAAAGAGCCCTAAGATCACCTG
GTTTCTAGAGAGTGGAGCCTGCTTCCTGGGCCCTAGGCCCCTCCCACAATGCTTGTCGCCGGTCTTCTTCTCTGGGCTTCCCTACTGACC
GGGGCCTGGCCATCCTTCCCCACCCAGGACCACCTCCCGGCCACGCCCCGGGTCCGGCTCTCATTCAAAGAGCTGAAGGCCACAGGCACC
GCCCACTTCTTCAACTTCCTGCTCAACACAACCGACTACCGAATCTTGCTCAAGGACGAGGACCACGACCGCATGTACGTGGGCAGCAAG
GACTACGTGCTGTCCCTGGACCTGCACGACATCAACCGCGAGCCCCTCATTATACACTGGGCAGCCTCCCCACAGCGCATCGAGGAATGC
GTGCTCTCAGGCAAGGATGTCAACGGCGAGTGTGGGAACTTCGTCAGGCTCATCCAGCCCTGGAACCGAACACACCTGTATGTGTGCGGG
ACAGGTGCCTACAACCCCATGTGCACCTATGTGAACCGCGGACGCCGCGCCCAGGATTACATCTTCTACCTGGAGCCTGAGCGACTCGAG
TCAGGGAAGGGCAAGTGTCCGTACGATCCCAAGCTGGACACAGCATCGGCCCTCATCATGACAGAGGCCAAGCAAGAATTAATAACCTAC
CCTCAGCCTCAGAAAACATCCATACCAGCACCATTGGAAAAACAGCCCAACCAGCCCCTAAGACCAGCTGATAAGGAACCTGAACCCAGG
AAGAGGGAAGAAGGCCAAGAGTCACGCTTAGGACATCAAAAGAGAGAAGCAGAAAGGTATCTGCCTCCTTCTCGAAGGGAAGGGCCAACT
TTCCGAAGAGACCGAGAGAGGGAGTCATGGTCTGGAGAGACACGCCAGGATGGAGAGAGCAAAACTATCATGCTAAAGCGTATCTATCGT
TCCACACCACCTGAGGTGATAGTGGAAGTGCTGGAGCCCTATGTCCGCCTTACTACTGCCAACGTCCGTATCATCAAGAACAGAACAGGC
CCTATGGGGCATACCTATGGCTTTATTGACCTCGACTCCCATGCGGAAGCTCTTCGTGTGGTGAAGATCTTACAGAACCTTGATCCGCCA
TTTAGCATTGATGGGAAGATGGTAGCTGTAAACCTGGCCACTGGAAAACGAAGAAATGATTCTGGGGACCATTCTGACCACATGCATTAC
TATCAGGGTAAAAAATATTTCCGAGATAGGAGGGGAGGTGGCAGAAATTCAGACTGGTCTTCAGATACAAATCGACAAGGACAACAGTCA
TCATCTGACTGCTACATATATGATTCTGCTACTGGCTACTATTATGACCCCTTGGCAGGAACTTATTATGACCCCAATACCCAGCAAGAA
GTCTATGTGCCCCAGGATCCTGGATTACCTGAGGAAGAAGAGATCAAGGAAAAAAAACCCACCAGTCAAGGAAAGTCAAGTAGCAAGAAG
GAAATGTCTAAAAGAGATGGCAAGGAGAAAAAAGACAGAGGAGTGACGAGGTTTCAGGAAAATGCCAGTGAAGGGAAGGCCCCTGCAGAA
GACGTCTTTAAGAAGCCCCTGCCTCCTACTGTGAAGAAGGAAGAGAGTCCCCCTCCACCTAAAGTGGTAAACCCACTGATCGGCCTCTTG
GGTGAATATGGAGGAGACAGTGACTATGAGGAGGAAGAAGAGGAGGAACAGACCCCTCCCCCACAGCCCCGCACAGCACAGCCCCAGAAG
CGAGAGGAGCAAACCAAGAAGGAGAATGAAGAAGACAAACTCACTGACTGGAATAAACTGGCTTGTCTGCTTTGCAGAAGGCAGTTTCCC
AATAAAGAAGTTCTGATCAAACACCAGCAGCTGTCAGACCTGCACAAGCAAAACCTGGAAATCCACCGGAAGATAAAACAGTCTGAGCAG
GAGCTAGCCTATCTGGAAAGGAGAGAACGAGAGGGAAAGTTTAAAGGAAGAGGAAATGATCGCAGGGAAAAGCTCCAGTCTTTTGACTCT
CCAGAAAGGAAACGGATTAAGTACTCCAGGGAAACTGACAGTGATCGTAAACTTGTTGATAAAGAAGATATCGACACTAGCAGCAAAGGA
GGCTGTGTCCAACAGGCTACTGGCTGGAGGAAAGGGACAGGCCTGGGATATGGCCATCCTGGATTGGCTTCATCAGAGGAGGCTGAAGGC
CGGATGAGGGGCCCCAGTGTTGGAGCCTCAGGAAGAACCAGCAAAAGACAGTCCAACGAGACTTACCGAGATGCTGTTCGAAGAGTCATG
TTTGCTCGATATAAAGAACTCGATTAAGAAAGGAGACAAGTTCCATGGGATACAACCTCCCTCTTGTTTTGTTTGTCTCTCCTTTTCTTT

>80297_80297_7_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000434342_RBM6_chr3_50095161_ENST00000266022_length(amino acids)=742AA_BP=184
MLVAGLLLWASLLTGAWPSFPTQDHLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPL
IIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQDYIFYLEPERLESGKGKCPYDPKLDTAS
ALIMTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADKEPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQ
DGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGK
RRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNRQGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIK
EKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEE
QTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKG
RGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGLGYGHPGLASSEEAEGRMRGPSVGASGRTSKR

--------------------------------------------------------------
>80297_80297_8_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000434342_RBM6_chr3_50095161_ENST00000442092_length(transcript)=2663nt_BP=868nt
CTGACTGGTGCTCCCTCTCTTCCATCTTGGGCTGTCTGCATGTGTCTCATTCCCCCACTCTCTCCTGTGCCTCCCCTCTACCGTAATAAT
CAGGTCCAGGTTTCTCTGTACTGGGAGAAGACCTGTGGCTGGAGCAGGCAGGGATGCACCCTATCTGTTCCCCATTCCTCCAGGTGGGAG
GGAGAAGGAGTAACCCACTTTATTGGCCACAGATGCAGGGGAGAAAGGAGAAAGCATGCTGGGAGCTGGAAAGAGCCCTAAGATCACCTG
GTTTCTAGAGAGTGGAGCCTGCTTCCTGGGCCCTAGGCCCCTCCCACAATGCTTGTCGCCGGTCTTCTTCTCTGGGCTTCCCTACTGACC
GGGGCCTGGCCATCCTTCCCCACCCAGGACCACCTCCCGGCCACGCCCCGGGTCCGGCTCTCATTCAAAGAGCTGAAGGCCACAGGCACC
GCCCACTTCTTCAACTTCCTGCTCAACACAACCGACTACCGAATCTTGCTCAAGGACGAGGACCACGACCGCATGTACGTGGGCAGCAAG
GACTACGTGCTGTCCCTGGACCTGCACGACATCAACCGCGAGCCCCTCATTATACACTGGGCAGCCTCCCCACAGCGCATCGAGGAATGC
GTGCTCTCAGGCAAGGATGTCAACGGCGAGTGTGGGAACTTCGTCAGGCTCATCCAGCCCTGGAACCGAACACACCTGTATGTGTGCGGG
ACAGGTGCCTACAACCCCATGTGCACCTATGTGAACCGCGGACGCCGCGCCCAGGATTACATCTTCTACCTGGAGCCTGAGCGACTCGAG
TCAGGGAAGGGCAAGTGTCCGTACGATCCCAAGCTGGACACAGCATCGGCCCTCATCATGACAGAGGCCAAGCAAGAATTAATAACCTAC
CCTCAGCCTCAGAAAACATCCATACCAGCACCATTGGAAAAACAGCCCAACCAGCCCCTAAGACCAGCTGATAAGGAACCTGAACCCAGG
AAGAGGGAAGAAGGCCAAGAGTCACGCTTAGGACATCAAAAGAGAGAAGCAGAAAGGTATCTGCCTCCTTCTCGAAGGGAAGGGCCAACT
TTCCGAAGAGACCGAGAGAGGGAGTCATGGTCTGGAGAGACACGCCAGGATGGAGAGAGCAAAACTATCATGCTAAAGCGTATCTATCGT
TCCACACCACCTGAGGTGATAGTGGAAGTGCTGGAGCCCTATGTCCGCCTTACTACTGCCAACGTCCGTATCATCAAGAACAGAACAGGC
CCTATGGGGCATACCTATGGCTTTATTGACCTCGACTCCCATGCGGAAGCTCTTCGTGTGGTGAAGATCTTACAGAACCTTGATCCGCCA
TTTAGCATTGATGGGAAGATGGTAGCTGTAAACCTGGCCACTGGAAAACGAAGAAATGATTCTGGGGACCATTCTGACCACATGCATTAC
TATCAGGGTAAAAAATATTTCCGAGATAGGAGGGGAGGTGGCAGAAATTCAGACTGGTCTTCAGATACAAATCGACAAGGACAACAGTCA
TCATCTGACTGCTACATATATGATTCTGCTACTGGCTACTATTATGACCCCTTGGCAGGAACTTATTATGACCCCAATACCCAGCAAGAA
GTCTATGTGCCCCAGGATCCTGGATTACCTGAGGAAGAAGAGATCAAGGAAAAAAAACCCACCAGTCAAGGAAAGTCAAGTAGCAAGAAG
GAAATGTCTAAAAGAGATGGCAAGGAGAAAAAAGACAGAGGAGTGACGAGGTTTCAGGAAAATGCCAGTGAAGGGAAGGCCCCTGCAGAA
GACGTCTTTAAGAAGCCCCTGCCTCCTACTGTGAAGAAGGAAGAGAGTCCCCCTCCACCTAAAGTGGTAAACCCACTGATCGGCCTCTTG
GGTGAATATGGAGGAGACAGTGACTATGAGGAGGAAGAAGAGGAGGAACAGACCCCTCCCCCACAGCCCCGCACAGCACAGCCCCAGAAG
CGAGAGGAGCAAACCAAGAAGGAGAATGAAGAAGACAAACTCACTGACTGGAATAAACTGGCTTGTCTGCTTTGCAGAAGGCAGTTTCCC
AATAAAGAAGTTCTGATCAAACACCAGCAGCTGTCAGACCTGCACAAGCAAAACCTGGAAATCCACCGGAAGATAAAACAGTCTGAGCAG
GAGCTAGCCTATCTGGAAAGGAGAGAACGAGAGGGAAAGTTTAAAGGAAGAGGAAATGATCGCAGGGAAAAGCTCCAGTCTTTTGACTCT
CCAGAAAGGAAACGGATTAAGTACTCCAGGGAAACTGACAGTGATCGTAAACTTGTTGATAAAGAAGATATCGACACTAGCAGCAAAGGA
GGCTGTGTCCAACAGGCTACTGGCTGGAGGAAAGGGACAGGCCTGGGATATGGCCATCCTGGATTGGCTTCATCAGAGGAGGCTGAAGGC
CGGATGAGGGGCCCCAGTGTTGGAGCCTCAGGAAGAACCAGCAAAAGACAGTCCAACGAGACTTACCGAGATGCTGTTCGAAGAGTCATG
TTTGCTCGATATAAAGAACTCGATTAAGAAAGGAGACAAGTTCCATGGGATACAACCTCCCTCTTGTTTTGTTTGTCTCTCCTTTTCTTT

>80297_80297_8_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000434342_RBM6_chr3_50095161_ENST00000442092_length(amino acids)=742AA_BP=184
MLVAGLLLWASLLTGAWPSFPTQDHLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPL
IIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQDYIFYLEPERLESGKGKCPYDPKLDTAS
ALIMTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADKEPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQ
DGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGK
RRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNRQGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIK
EKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEE
QTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKG
RGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGLGYGHPGLASSEEAEGRMRGPSVGASGRTSKR

--------------------------------------------------------------
>80297_80297_9_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000434342_RBM6_chr3_50095161_ENST00000443081_length(transcript)=2662nt_BP=868nt
CTGACTGGTGCTCCCTCTCTTCCATCTTGGGCTGTCTGCATGTGTCTCATTCCCCCACTCTCTCCTGTGCCTCCCCTCTACCGTAATAAT
CAGGTCCAGGTTTCTCTGTACTGGGAGAAGACCTGTGGCTGGAGCAGGCAGGGATGCACCCTATCTGTTCCCCATTCCTCCAGGTGGGAG
GGAGAAGGAGTAACCCACTTTATTGGCCACAGATGCAGGGGAGAAAGGAGAAAGCATGCTGGGAGCTGGAAAGAGCCCTAAGATCACCTG
GTTTCTAGAGAGTGGAGCCTGCTTCCTGGGCCCTAGGCCCCTCCCACAATGCTTGTCGCCGGTCTTCTTCTCTGGGCTTCCCTACTGACC
GGGGCCTGGCCATCCTTCCCCACCCAGGACCACCTCCCGGCCACGCCCCGGGTCCGGCTCTCATTCAAAGAGCTGAAGGCCACAGGCACC
GCCCACTTCTTCAACTTCCTGCTCAACACAACCGACTACCGAATCTTGCTCAAGGACGAGGACCACGACCGCATGTACGTGGGCAGCAAG
GACTACGTGCTGTCCCTGGACCTGCACGACATCAACCGCGAGCCCCTCATTATACACTGGGCAGCCTCCCCACAGCGCATCGAGGAATGC
GTGCTCTCAGGCAAGGATGTCAACGGCGAGTGTGGGAACTTCGTCAGGCTCATCCAGCCCTGGAACCGAACACACCTGTATGTGTGCGGG
ACAGGTGCCTACAACCCCATGTGCACCTATGTGAACCGCGGACGCCGCGCCCAGGATTACATCTTCTACCTGGAGCCTGAGCGACTCGAG
TCAGGGAAGGGCAAGTGTCCGTACGATCCCAAGCTGGACACAGCATCGGCCCTCATCATGACAGAGGCCAAGCAAGAATTAATAACCTAC
CCTCAGCCTCAGAAAACATCCATACCAGCACCATTGGAAAAACAGCCCAACCAGCCCCTAAGACCAGCTGATAAGGAACCTGAACCCAGG
AAGAGGGAAGAAGGCCAAGAGTCACGCTTAGGACATCAAAAGAGAGAAGCAGAAAGGTATCTGCCTCCTTCTCGAAGGGAAGGGCCAACT
TTCCGAAGAGACCGAGAGAGGGAGTCATGGTCTGGAGAGACACGCCAGGATGGAGAGAGCAAAACTATCATGCTAAAGCGTATCTATCGT
TCCACACCACCTGAGGTGATAGTGGAAGTGCTGGAGCCCTATGTCCGCCTTACTACTGCCAACGTCCGTATCATCAAGAACAGAACAGGC
CCTATGGGGCATACCTATGGCTTTATTGACCTCGACTCCCATGCGGAAGCTCTTCGTGTGGTGAAGATCTTACAGAACCTTGATCCGCCA
TTTAGCATTGATGGGAAGATGGTAGCTGTAAACCTGGCCACTGGAAAACGAAGAAATGATTCTGGGGACCATTCTGACCACATGCATTAC
TATCAGGGTAAAAAATATTTCCGAGATAGGAGGGGAGGTGGCAGAAATTCAGACTGGTCTTCAGATACAAATCGACAAGGACAACAGTCA
TCATCTGACTGCTACATATATGATTCTGCTACTGGCTACTATTATGACCCCTTGGCAGGAACTTATTATGACCCCAATACCCAGCAAGAA
GTCTATGTGCCCCAGGATCCTGGATTACCTGAGGAAGAAGAGATCAAGGAAAAAAAACCCACCAGTCAAGGAAAGTCAAGTAGCAAGAAG
GAAATGTCTAAAAGAGATGGCAAGGAGAAAAAAGACAGAGGAGTGACGAGGTTTCAGGAAAATGCCAGTGAAGGGAAGGCCCCTGCAGAA
GACGTCTTTAAGAAGCCCCTGCCTCCTACTGTGAAGAAGGAAGAGAGTCCCCCTCCACCTAAAGTGGTAAACCCACTGATCGGCCTCTTG
GGTGAATATGGAGGAGACAGTGACTATGAGGAGGAAGAAGAGGAGGAACAGACCCCTCCCCCACAGCCCCGCACAGCACAGCCCCAGAAG
CGAGAGGAGCAAACCAAGAAGGAGAATGAAGAAGACAAACTCACTGACTGGAATAAACTGGCTTGTCTGCTTTGCAGAAGGCAGTTTCCC
AATAAAGAAGTTCTGATCAAACACCAGCAGCTGTCAGACCTGCACAAGCAAAACCTGGAAATCCACCGGAAGATAAAACAGTCTGAGCAG
GAGCTAGCCTATCTGGAAAGGAGAGAACGAGAGGGAAAGTTTAAAGGAAGAGGAAATGATCGCAGGGAAAAGCTCCAGTCTTTTGACTCT
CCAGAAAGGAAACGGATTAAGTACTCCAGGGAAACTGACAGTGATCGTAAACTTGTTGATAAAGAAGATATCGACACTAGCAGCAAAGGA
GGCTGTGTCCAACAGGCTACTGGCTGGAGGAAAGGGACAGGCCTGGGATATGGCCATCCTGGATTGGCTTCATCAGAGGAGGCTGAAGGC
CGGATGAGGGGCCCCAGTGTTGGAGCCTCAGGAAGAACCAGCAAAAGACAGTCCAACGAGACTTACCGAGATGCTGTTCGAAGAGTCATG
TTTGCTCGATATAAAGAACTCGATTAAGAAAGGAGACAAGTTCCATGGGATACAACCTCCCTCTTGTTTTGTTTGTCTCTCCTTTTCTTT

>80297_80297_9_SEMA3F-RBM6_SEMA3F_chr3_50214294_ENST00000434342_RBM6_chr3_50095161_ENST00000443081_length(amino acids)=742AA_BP=184
MLVAGLLLWASLLTGAWPSFPTQDHLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPL
IIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQDYIFYLEPERLESGKGKCPYDPKLDTAS
ALIMTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADKEPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQ
DGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGK
RRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNRQGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIK
EKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEE
QTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKG
RGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGLGYGHPGLASSEEAEGRMRGPSVGASGRTSKR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SEMA3F-RBM6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for SEMA3F-RBM6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for SEMA3F-RBM6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource