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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SEPT7-GLI3 (FusionGDB2 ID:80496)

Fusion Gene Summary for SEPT7-GLI3

check button Fusion gene summary
Fusion gene informationFusion gene name: SEPT7-GLI3
Fusion gene ID: 80496
HgeneTgene
Gene symbol

SEPT7

GLI3

Gene ID

989

2737

Gene nameseptin 7GLI family zinc finger 3
SynonymsCDC10|CDC3|NBLA02942|SEPT7|SEPT7AACLS|GCPS|GLI3-190|GLI3FL|PAP-A|PAPA|PAPA1|PAPB|PHS|PPDIV
Cytomap

7p14.2

7p14.1

Type of geneprotein-codingprotein-coding
Descriptionseptin-7CDC10 (cell division cycle 10, S. cerevisiae, homolog)CDC10 protein homologseptin 7 variant 4transcriptional activator GLI3GLI-Kruppel family member GLI3glioma-associated oncogene family zinc finger 3oncogene GLI3zinc finger protein GLI3
Modification date2020031320200313
UniProtAcc.

P10071

Ensembl transtripts involved in fusion geneENST00000350320, ENST00000399034, 
ENST00000399035, ENST00000435235, 
ENST00000469679, ENST00000494488, 
ENST00000432293, ENST00000475109, 
ENST00000479210, ENST00000437480, 
ENST00000395925, 
Fusion gene scores* DoF score8 X 5 X 7=2807 X 7 X 5=245
# samples 88
** MAII scorelog2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/245*10)=-1.61470984411521
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SEPT7 [Title/Abstract] AND GLI3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSEPT7(35872510)-GLI3(42116456), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSEPT7

GO:0030336

negative regulation of cell migration

-

HgeneSEPT7

GO:0043065

positive regulation of apoptotic process

-

HgeneSEPT7

GO:2000134

negative regulation of G1/S transition of mitotic cell cycle

-

TgeneGLI3

GO:0000122

negative regulation of transcription by RNA polymerase II

10693759|12435627|19084012

TgeneGLI3

GO:0045892

negative regulation of transcription, DNA-templated

12435627|16254602|19084012

TgeneGLI3

GO:0045944

positive regulation of transcription by RNA polymerase II

17000779

TgeneGLI3

GO:0090090

negative regulation of canonical Wnt signaling pathway

17331723


check buttonFusion gene breakpoints across SEPT7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GLI3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-69-7978-01ASEPT7chr7

35872510

+GLI3chr7

42116456

-


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Fusion Gene ORF analysis for SEPT7-GLI3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000350320ENST00000479210SEPT7chr7

35872510

+GLI3chr7

42116456

-
5CDS-5UTRENST00000399034ENST00000479210SEPT7chr7

35872510

+GLI3chr7

42116456

-
5CDS-5UTRENST00000399035ENST00000479210SEPT7chr7

35872510

+GLI3chr7

42116456

-
5CDS-5UTRENST00000435235ENST00000479210SEPT7chr7

35872510

+GLI3chr7

42116456

-
5CDS-5UTRENST00000469679ENST00000479210SEPT7chr7

35872510

+GLI3chr7

42116456

-
5CDS-5UTRENST00000494488ENST00000479210SEPT7chr7

35872510

+GLI3chr7

42116456

-
5CDS-intronENST00000350320ENST00000437480SEPT7chr7

35872510

+GLI3chr7

42116456

-
5CDS-intronENST00000399034ENST00000437480SEPT7chr7

35872510

+GLI3chr7

42116456

-
5CDS-intronENST00000399035ENST00000437480SEPT7chr7

35872510

+GLI3chr7

42116456

-
5CDS-intronENST00000435235ENST00000437480SEPT7chr7

35872510

+GLI3chr7

42116456

-
5CDS-intronENST00000469679ENST00000437480SEPT7chr7

35872510

+GLI3chr7

42116456

-
5CDS-intronENST00000494488ENST00000437480SEPT7chr7

35872510

+GLI3chr7

42116456

-
In-frameENST00000350320ENST00000395925SEPT7chr7

35872510

+GLI3chr7

42116456

-
In-frameENST00000399034ENST00000395925SEPT7chr7

35872510

+GLI3chr7

42116456

-
In-frameENST00000399035ENST00000395925SEPT7chr7

35872510

+GLI3chr7

42116456

-
In-frameENST00000435235ENST00000395925SEPT7chr7

35872510

+GLI3chr7

42116456

-
In-frameENST00000469679ENST00000395925SEPT7chr7

35872510

+GLI3chr7

42116456

-
In-frameENST00000494488ENST00000395925SEPT7chr7

35872510

+GLI3chr7

42116456

-
intron-3CDSENST00000432293ENST00000395925SEPT7chr7

35872510

+GLI3chr7

42116456

-
intron-3CDSENST00000475109ENST00000395925SEPT7chr7

35872510

+GLI3chr7

42116456

-
intron-5UTRENST00000432293ENST00000479210SEPT7chr7

35872510

+GLI3chr7

42116456

-
intron-5UTRENST00000475109ENST00000479210SEPT7chr7

35872510

+GLI3chr7

42116456

-
intron-intronENST00000432293ENST00000437480SEPT7chr7

35872510

+GLI3chr7

42116456

-
intron-intronENST00000475109ENST00000437480SEPT7chr7

35872510

+GLI3chr7

42116456

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000435235SEPT7chr735872510+ENST00000395925GLI3chr742116456-81984429348171574
ENST00000469679SEPT7chr735872510+ENST00000395925GLI3chr742116456-811535911547341539
ENST00000399034SEPT7chr735872510+ENST00000395925GLI3chr742116456-812136511547401541
ENST00000350320SEPT7chr735872510+ENST00000395925GLI3chr742116456-811535911547341539
ENST00000399035SEPT7chr735872510+ENST00000395925GLI3chr742116456-7922166045411513
ENST00000494488SEPT7chr735872510+ENST00000395925GLI3chr742116456-788312711745021461

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000435235ENST00000395925SEPT7chr735872510+GLI3chr742116456-0.0030084950.9969915
ENST00000469679ENST00000395925SEPT7chr735872510+GLI3chr742116456-0.0020769830.9979231
ENST00000399034ENST00000395925SEPT7chr735872510+GLI3chr742116456-0.0020619340.9979381
ENST00000350320ENST00000395925SEPT7chr735872510+GLI3chr742116456-0.0020638270.99793625
ENST00000399035ENST00000395925SEPT7chr735872510+GLI3chr742116456-0.001694710.9983053
ENST00000494488ENST00000395925SEPT7chr735872510+GLI3chr742116456-0.0020655070.99793446

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Fusion Genomic Features for SEPT7-GLI3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SEPT7-GLI3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:35872510/chr7:42116456)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.GLI3

P10071

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in regulating the size of the zone of distal chondrocytes, in restricting the zone of PTHLH expression in distal cells and in activating chondrocyte proliferation. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'. {ECO:0000269|PubMed:10693759, ECO:0000269|PubMed:11238441, ECO:0000269|PubMed:17764085}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneGLI3chr7:35872510chr7:42116456ENST000003959252151492_15121221581.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneGLI3chr7:35872510chr7:42116456ENST00000395925215480_5051221581.0Zinc fingerC2H2-type 1
TgeneGLI3chr7:35872510chr7:42116456ENST00000395925215513_5401221581.0Zinc fingerC2H2-type 2
TgeneGLI3chr7:35872510chr7:42116456ENST00000395925215546_5701221581.0Zinc fingerC2H2-type 3
TgeneGLI3chr7:35872510chr7:42116456ENST00000395925215576_6011221581.0Zinc fingerC2H2-type 4
TgeneGLI3chr7:35872510chr7:42116456ENST00000395925215607_6321221581.0Zinc fingerC2H2-type 5

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSEPT7chr7:35872510chr7:42116456ENST00000399034+314332_43757439.0Coiled coilOntology_term=ECO:0000255
HgeneSEPT7chr7:35872510chr7:42116456ENST00000399034+31447_31657439.0DomainSeptin-type G
HgeneSEPT7chr7:35872510chr7:42116456ENST00000399034+314195_20357439.0Nucleotide bindingGTP
HgeneSEPT7chr7:35872510chr7:42116456ENST00000399034+314113_11657439.0RegionG3 motif
HgeneSEPT7chr7:35872510chr7:42116456ENST00000399034+314194_19757439.0RegionG4 motif
HgeneSEPT7chr7:35872510chr7:42116456ENST00000399034+31457_6457439.0RegionG1 motif


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Fusion Gene Sequence for SEPT7-GLI3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80496_80496_1_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000350320_GLI3_chr7_42116456_ENST00000395925_length(transcript)=8115nt_BP=359nt
AGCCTCGTCTGAGGGGGCGGGGGACGGAGGAGGGAGCGGGAGTCGAGCGAGAGCCTGTGGAGGAGTCCGCCTGCTGTAGCGTGCGTAAGC
AAGGCAGCTACGCCGGGCGGCTACGCTGCGGAATCGGCGTAGGCGCCTTTGGAGAATCGGCGGGCTGCGCTCCGCTGGGGCTGGTCGCGG
AGGGGGGGAGGGGATGTCGGTCAGTGCGAGATCCGCTGCTGCTGAGGAGAGGAGCGTCAACAGCAGCACCATGGGTCAACAGAAGAACCT
TGAAGGCTATGTGGGATTTGCCAATCTCCCAAATCAAGTATACAGAAAATCGGTGAAGAGAGGTTTTGAATTCACGCTTATGGTAGTGGA
CCCTCCTCATCTTTTCCCTGCCTTCCATCCTCCTGTACCAATTGATGCCAGACATCATGAGGGCCGTTACCATTACGATCCATCTCCGAT
TCCTCCATTGCATATGACTTCCGCCTTATCTAGTAGCCCTACGTATCCGGACCTGCCCTTCATTAGGATCTCCCCACACCGGAACCCCAC
TGCTGCTTCCGAGTCTCCCTTCAGCCCTCCACATCCCTACATTAATCCCTACATGGACTATATCCGCTCCTTGCACAGCAGCCCATCGCT
CTCCATGATCTCAGCAACCCGTGGGCTGAGCCCTACAGATGCGCCCCATGCAGGAGTCAGCCCAGCAGAATACTATCATCAGATGGCCCT
GCTAACTGGCCAGCGCAGCCCCTATGCAGACATTATTCCCTCAGCTGCCACCGCCGGCACGGGGGCCATCCACATGGAATATCTTCATGC
TATGGATAGCACCAGATTCTCCAGCCCCAGGCTGTCAGCCAGGCCGAGCCGAAAACGTACACTGTCCATATCACCACTCTCCGATCATAG
CTTTGACCTTCAGACCATGATAAGGACGTCTCCCAACTCCTTGGTCACGATTCTCAATAATTCCCGTAGCAGCTCTTCAGCAAGTGGCTC
CTATGGTCACTTATCTGCAAGTGCAATCAGCCCTGCCTTGAGCTTCACCTACTCTTCCGCGCCCGTCTCTCTCCACATGCATCAGCAGAT
CCTAAGCCGACAACAGAGCTTAGGTTCAGCCTTTGGACACAGCCCTCCACTCATCCACCCTGCCCCAACTTTTCCAACACAGAGGCCTAT
TCCAGGGATCCCTACGGTTCTGAACCCCGTCCAGGTCAGCTCCGGCCCTTCTGAGTCCTCACAGAACAAGCCCACGAGTGAGTCTGCAGT
GAGCAGCACTGGTGACCCGATGCACAACAAGAGGTCCAAGATCAAACCCGATGAAGACCTCCCCAGCCCAGGGGCTCGGGGGCAGCAGGA
ACAGCCCGAAGGAACAACCCTTGTCAAGGAGGAAGGGGACAAAGATGAAAGCAAACAGGAGCCTGAAGTCATCTATGAGACAAACTGCCA
CTGGGAAGGCTGCGCGAGGGAGTTCGACACCCAAGAGCAGCTTGTGCACCATATAAATAACGACCATATTCATGGAGAGAAGAAGGAGTT
CGTGTGCAGGTGGCTGGACTGCTCAAGAGAGCAGAAACCCTTCAAAGCCCAGTATATGTTGGTAGTGCATATGAGAAGACACACGGGCGA
GAAGCCTCACAAATGCACTTTTGAAGGTTGCACAAAGGCCTACTCGAGACTAGAAAACTTGAAAACACACTTGAGATCTCACACTGGAGA
GAAACCATACGTCTGTGAGCACGAAGGTTGCAACAAGGCTTTCTCAAATGCCTCTGATCGCGCCAAACACCAAAACAGAACGCATTCCAA
TGAGAAACCATATGTGTGCAAAATCCCAGGCTGCACTAAGCGTTACACAGACCCAAGCTCCCTCCGGAAACATGTGAAGACAGTGCATGG
CCCAGAGGCTCATGTCACCAAGAAGCAGCGAGGGGACATCCATCCTCGGCCGCCACCCCCGAGAGATTCCGGCAGCCATTCACAGTCCAG
GTCGCCTGGCCGACCGACTCAGGGAGCCCTTGGTGAGCAGCAGGACCTCAGCAACACTACCTCAAAGCGGGAAGAATGCCTCCAGGTGAA
AACCGTCAAGGCAGAGAAGCCAATGACATCTCAGCCAAGCCCTGGTGGTCAGTCTTCATGCAGCAGCCAACAGTCCCCCATCAGCAACTA
TTCCAACAGTGGGCTCGAGCTTCCTCTGACCGATGGAGGTAGTATAGGAGACCTCAGTGCCATCGATGAAACCCCAATCATGGACTCAAC
CATTTCCACTGCAACCACAGCCCTTGCTTTGCAAGCCAGGAGAAACCCGGCAGGGACCAAATGGATGGAGCACGTAAAACTAGAAAGGCT
AAAACAAGTGAATGGAATGTTTCCGCGACTGAACCCCATTCTACCCCCTAAAGCCCCTGCGGTCTCTCCTCTCATAGGAAATGGCACACA
GTCCAACAACACCTGCAGCTTGGGTGGGCCCATGACGCTTCTCCCGGGCAGAAGCGACCTCTCTGGGGTGGACGTCACTATGCTGAACAT
GCTCAACAGAAGGGACAGCAGCGCCAGCACCATCAGCTCGGCCTACCTGAGCAGCCGCCGCTCCTCAGGGATCTCGCCCTGCTTCTCCAG
CCGCCGCTCCAGCGAGGCGTCACAGGCCGAGGGCCGGCCGCAGAACGTGAGCGTGGCCGACTCCTACGACCCCATCTCCACCGACGCCTC
GCGCCGCTCCAGCGAAGCCAGCCAGAGCGACGGCCTGCCCAGCCTGCTCAGCCTCACGCCCGCCCAGCAGTACCGCCTCAAGGCCAAGTA
CGCGGCTGCCACAGGAGGGCCGCCGCCGACGCCCCTGCCCAACATGGAGAGGATGAGCCTGAAGACGCGCCTGGCGCTGCTCGGGGATGC
CCTCGAGCCTGGCGTGGCCCTGCCTCCAGTTCATGCCCCGAGGAGGTGCAGCGACGGGGGAGCCCACGGCTACGGGCGGCGCCACCTGCA
GCCGCACGATGCGCCGGGCCACGGCGTGAGGAGGGCCAGCGACCCGGTGCGGACAGGCTCCGAGGGCCTGGCCCTGCCTCGTGTGCCGCG
CTTCAGCAGCCTCAGCAGCTGCAACCCCCCGGCGATGGCCACGTCCGCGGAGAAGCGCAGTCTCGTGCTTCAGAATTACACGCGGCCCGA
GGGCGGCCAGTCCCGAAACTTCCACTCGTCCCCCTGTCCTCCCAGCATCACCGAGAACGTCACCCTGGAGTCCCTGACCATGGACGCTGA
TGCCAACCTGAACGATGAGGATTTCCTGCCGGACGACGTGGTGCAGTATTTAAATTCCCAGAACCAAGCAGGGTACGAGCAGCACTTCCC
CAGCGCCCTCCCGGACGACAGCAAAGTGCCCCACGGGCCCGGTGACTTTGACGCGCCCGGGCTGCCAGACAGCCACGCTGGCCAGCAGTT
CCATGCCCTCGAGCAGCCCTGCCCCGAGGGCAGCAAAACCGACCTGCCCATTCAGTGGAACGAAGTCAGCTCCGGAAGCGCCGACCTGTC
CTCCTCCAAGCTCAAGTGTGGGCCGCGGCCCGCTGTGCCGCAGACTCGCGCCTTTGGGTTCTGCAACGGCATGGTCGTCCACCCGCAGAA
CCCCTTGAGGAGCGGGCCTGCTGGGGGCTATCAGACCCTCGGGGAGAACAGCAACCCCTACGGTGGCCCAGAGCACTTGATGCTCCACAA
CAGCCCCGGAAGTGGCACCAGTGGAAACGCCTTCCATGAACAGCCCTGTAAGGCCCCGCAGTATGGGAACTGTCTCAACAGGCAGCCAGT
GGCCCCTGGTGCACTCGACGGTGCCTGTGGTGCCGGGATTCAAGCCTCAAAGCTGAAGAGCACCCCCATGCAAGGGAGCGGGGGCCAGCT
GAATTTCGGCCTGCCGGTAGCGCCAAATGAGTCAGCTGGCAGCATGGTGAATGGCATGCAGAACCAGGACCCAGTGGGACAGGGGTACCT
GGCTCACCAGCTCCTCGGCGACAGCATGCAGCACCCGGGGGCAGGCCGCCCCGGTCAGCAGATGCTTGGGCAGATTAGTGCTACCTCACA
CATCAACATCTACCAAGGGCCAGAGAGCTGCCTGCCAGGGGCTCACGGCATGGGCAGCCAGCCGTCAAGCTTGGCAGTTGTCAGGGGCTA
CCAGCCATGTGCCAGCTTTGGGGGCAGCAGGCGCCAGGCTATGCCGAGGGACAGCCTTGCTCTGCAGTCAGGACAGCTCAGTGACACAAG
TCAGACCTGCAGGGTGAATGGTATCAAGATGGAGATGAAAGGGCAGCCCCATCCGCTGTGCTCTAATCTGCAGAATTACTCTGGTCAGTT
CTATGACCAAACCGTGGGCTTCAGTCAGCAAGACACGAAAGCTGGTTCATTCTCTATTTCAGACGCCAGCTGCCTGCTACAGGGGACCAG
CGCCAAAAACTCTGAGTTACTTTCCCCAGGTGCTAATCAGGTGACAAGCACAGTGGACAGCCTCGACAGCCATGACCTGGAAGGGGTACA
GATTGACTTCGATGCCATCATAGACGATGGGGACCACTCCAGCCTGATGTCGGGGGCCCTGAGCCCAAGTATCATTCAGAACCTTTCCCA
TAGCTCCTCCCGCCTCACCACGCCTCGGGCGTCCCTCCCATTCCCAGCGCTGTCCATGAGCACCACCAACATGGCTATCGGGGACATGAG
TTCTTTGCTGACCTCCCTAGCGGAAGAAAGCAAATTCCTTGCAGTTATGCAATAGGCTTTAGGAAAAAAAGACTGCAACCAACGGAAATC
AATAGGAGTTGAAGAGATTAAACTGACTTTGTTTTGGCTGTTTTTTTAGTTCTGTATGTATTTTAGCAATCTCATCTCACCTAACTGAGA
TGTGTTTCAATTATATTCCTTTTATGGAAAAGGACTCTGAAAAACCCTAAAGTATTCTAGGGAGAAACTGTCTTCCATTTCAGTTTTGAA
TCAGTATTGTTACACTCAAACCACCCTCTTTTTAAAAAAAAAAAAAAAAACTGTAAGCCCCGCCCCCTTTTTAGTAAACCGATGTAAATT
TGTGATGTGCATATTCTTCTTTCTTTTAGAAGAGCAGTCAAATTAAAGGATTTGACATGTTTTGCTGTTGCTCAAAGGAAATAGGAGTTG
GTGTGCTTGTGACCAAGGGGTTACACTTCCAGCTTTTAAAATTCTCCTTTACATGTGCTCAGTGTTTTGTTTTGTGTTTTGGTTTCTGTT
TTTTATTTTAATTCCCACATTGGGCACAAGAATCAGAATATGGATAGCTAGTTTAAGAAACTTTTGTGGGTGCACTGTAGCATAGATGAC
AGAATATTGATGTTCCCCCCATCTCCAATTCAGTTCAGGGCATTCCACAGTTAAACAGAAATGGGAACGTGGGGCTCTTATAAATGAAAT
GGGCGCTCACAGTTTTGGTTTTCAGCTCTTCATGTCTGTAAGTGTGCTTTGGGGGAGGCTATGTCTGTATGGTCGATTCTCAGTTATCAC
ATTTGCCTCTCCTCCCACTACCTTCATGAACATTCAGTGCTGTTTCGCACTGCAGTTAGAGAGAAGGGACGGACAGTTGGTGACACTCAG
CCACATTGCTACTTTTATCTGTTCTGGTAAGAAGTTAGATAGATGGTAGATTGAAGCAATTGGGTAGAATTAGTTGGGGGAATATTTATG
AGTTGCTGTGTTTGTTGATTAGTTCCATCTCTTTCCCATTTTAACTGAGAATTGATTATATATAGCTCTAAGTATATAGGTATTTAAACA
ACCCCACAAGCGGCTGTATCAGTAACATTTATTAATTCCACTATAGTGAGGGAGGATTTCCATTCTAAATACCTTATTTTGAGGGATTTA
TAAAACTTAGTTGTAAAAGAGAAAGCCCACATAGTGGGAATAAATTGCTTCAGCCATTTTTAGTATTTGAGAGCACTAGGGAAGATGTTT
AGTAGCTGTGTGGATGCCTTTTTTCACACCCTGTCTATTGAATGCTGCATCCATTCACGAAGTTAAATGTTACATGCAGTTAGTCCTTAA
TGTGGACTGGATCTGTACTTTTGTTTTGGATTAAAACATTTAAAGATTTTTGAAGTGCAGCTACTCCCCACGTGCATTTGATACACATAA
AAGTCATACTGTGTGTGCACAAAGAGTACATGGATTTTCCAGCATATTGCTTTAAAAAATTATATAAACTGTTAAAATATTAACACCTCA
GGCTACCTGCTGTATTCTGTCCCATTGACCCCTGGAATTGGATTTACTGCAAGTGATTGATAATTCAATTATGTGGCTTTTCCCCTTTAA
TCTTGCCATTTAAATTACAGTAGAAAGACAAAATCAAGTAAAATAAAGTGTTAGATAATAGAAAGAGTGTTAAGACCAGCCCACTTTTCT
CATGTTTATGTTCTTTCATTTGGACCAAGAATCTCCGCATGGAGGTTGATTTGCCACTGGGGACTTTGGCTAAGACTATTAGGTTTGCTT
TCAACTAGATGTTCCTGAGACAAGCAGAGGGACACTGCAATTCCCCTTCCATGCCTGCTGTTCTCCCCCATGTAAGTCTTCTTTGAAATT
AACGGATGTGTCTCCTTTGGAACAGCCCCATAACAAAAGAGAACTACTGATCTGAGCATAGGAAAGTAGAGGCTCTACCACTTTTCAGTT
GAAAAAGCAAGACTTTCTCTGTGTTTCTGAAACAAGGCATAATGTTGTCACAGAATCAGAGATCCAGTCTCACTTTTCCACAAATCTCCA
AATCTCCAGTCTTATCTTGTGTGCTCTAATGGTTTGGTTCAATCCCTTTCCAACTCTTGTTTTCAAAGCATGGGGCCTGAGTGTTCTCCA
CTCCTCCTAAGAAAGGAGCTTGGGTGGAAGGGACCATGCTGACCTCCTCCATCAGAGGGCTCTTCCAGTAGTATTCTCGGATGCAACCTC
CATTTCTCAGTTACCATTATTTCCTGTATCAGCTTTGTCCTTCCTGGAGGGATGCACAGTGATCCGGCCCACCACTGTTGTTGTCTTGTG
CTTCTGCTCTTTCCTATGGTTTCAGGTTATTTTCTGGGTTTCCCCTATTCTTCTTTTATTTCTTTTTTTTTTTATATTTGCTTTCCTTTC
TACTGCTTTTAGATTTGCAGGAGATGCAAGTTTCAGCTCAATGTTTGGCTTCTCTCAATATGGAAATTTCAGAAGGACAGAGGAGAGGAG
GGAGGAAGAAGAAAGTATACTCCTCCAGAATTTCAGTGATCTGTTGTGGCAGTCCAGTGGAAGGAAGGTCTTTTGAGGTCACTTAGAAGC
ATCTTTTTGGGACATCCTTTTGGGATCTCTGTAGGCTAGGCATCTCATATCTTGAGACTCACCCCCAGCCTCCAAGCCTCTCTCCATTTC
TCTAACCTATGCATTTTAGAGCGAGAGGACCGCCTCACTAGTGTCACCATCCTGCCTTTTCTAAAACATGCAGGCTCACACATTCTACTC
CTGCTTAATGTCTGTGTTAAACGTTTTCTAACCATTTTTGTTTTATTTTTCTGAAAAAGTTAACCCCTCCCAACTCCTCACACATTGGCT
CTTCCTCTTGAGCCACAAAGTTTTGATTCTTGCGATGTATGTGCCTTATTTTATGTTAATCTTGTCAATGAGAGGGACCAGTTGGTGTTG
CCCAATCAGCACTCCAAGGCTGTGTGTGCACCAGCCAGAGAGCGCACGGTGGTAGCAGAGTCGAGGCTGTCTTGTATCCTGGTTTCATGT
GTTGTTTTGAACTGATAGGAGGATGTTCTCTTCTGACAAGTTACCCTTGTGTATCCTGCAGACATGTAAAATAAAATACAAGTTCATTTT
TTTCACCTTTTTTAGATTTTTTTAAAAAATAAAATGTGTAATCCTTTTTTTAAAAGAAACACATGTAAATACATTTAAGTATTGTAGGCA
TAGCGTTCAGATGTGACTGGCCCAGGCGTTCCTCGGACAAGCCTGCATTCCCCGTGATCACGCCCACCTCAAGCCCAGGGGCTGCAGCCC
AGCCACAGATGAACTCTACCTTTGCTTTCAGAACCACTTAGTCCTTTTGTAACAAAGAAAAAAAAATGTTTCTTACAATGTCAATAAAAA

>80496_80496_1_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000350320_GLI3_chr7_42116456_ENST00000395925_length(amino acids)=1539AA_BP=81
MRNRRRRLWRIGGLRSAGAGRGGGEGMSVSARSAAAEERSVNSSTMGQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVDPPHLFPAF
HPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISATRG
LSPTDAPHAGVSPAEYYHQMALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLSDHSFDLQTMIR
TSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLN
PVQVSSGPSESSQNKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYETNCHWEGCAREF
DTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHE
GCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPTQG
ALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATTAL
ALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTMLNMLNRRDSSA
STISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPISTDASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAATGGPP
PTPLPNMERMSLKTRLALLGDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGVRRASDPVRTGSEGLALPRVPRFSSLSSCN
PPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTMDADANLNDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDDSK
VPHGPGDFDAPGLPDSHAGQQFHALEQPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVHPQNPLRSGPAG
GYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNRQPVAPGALDGACGAGIQASKLKSTPMQGSGGQLNFGLPVAP
NESAGSMVNGMQNQDPVGQGYLAHQLLGDSMQHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAHGMGSQPSSLAVVRGYQPCASFGG
SRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPLCSNLQNYSGQFYDQTVGFSQQDTKAGSFSISDASCLLQGTSAKNSELLS
PGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIGDMSSLLTSLAE

--------------------------------------------------------------
>80496_80496_2_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000399034_GLI3_chr7_42116456_ENST00000395925_length(transcript)=8121nt_BP=365nt
AGCCTCGTCTGAGGGGGCGGGGGACGGAGGAGGGAGCGGGAGTCGAGCGAGAGCCTGTGGAGGAGTCCGCCTGCTGTAGCGTGCGTAAGC
AAGGCAGCTACGCCGGGCGGCTACGCTGCGGAATCGGCGTAGGCGCCTTTGGAGAATCGGCGGGCTGCGCTCCGCTGGGGCTGGTCGCGG
AGGGGGGGAGGGGATGTCGGTCAGTGCGAGATCCGCTGCTGCTGAGGAGAGGAGCGTCAACAGCAGCACCATGGAGGTTGCCCAACAGAA
GAACCTTGAAGGCTATGTGGGATTTGCCAATCTCCCAAATCAAGTATACAGAAAATCGGTGAAGAGAGGTTTTGAATTCACGCTTATGGT
AGTGGACCCTCCTCATCTTTTCCCTGCCTTCCATCCTCCTGTACCAATTGATGCCAGACATCATGAGGGCCGTTACCATTACGATCCATC
TCCGATTCCTCCATTGCATATGACTTCCGCCTTATCTAGTAGCCCTACGTATCCGGACCTGCCCTTCATTAGGATCTCCCCACACCGGAA
CCCCACTGCTGCTTCCGAGTCTCCCTTCAGCCCTCCACATCCCTACATTAATCCCTACATGGACTATATCCGCTCCTTGCACAGCAGCCC
ATCGCTCTCCATGATCTCAGCAACCCGTGGGCTGAGCCCTACAGATGCGCCCCATGCAGGAGTCAGCCCAGCAGAATACTATCATCAGAT
GGCCCTGCTAACTGGCCAGCGCAGCCCCTATGCAGACATTATTCCCTCAGCTGCCACCGCCGGCACGGGGGCCATCCACATGGAATATCT
TCATGCTATGGATAGCACCAGATTCTCCAGCCCCAGGCTGTCAGCCAGGCCGAGCCGAAAACGTACACTGTCCATATCACCACTCTCCGA
TCATAGCTTTGACCTTCAGACCATGATAAGGACGTCTCCCAACTCCTTGGTCACGATTCTCAATAATTCCCGTAGCAGCTCTTCAGCAAG
TGGCTCCTATGGTCACTTATCTGCAAGTGCAATCAGCCCTGCCTTGAGCTTCACCTACTCTTCCGCGCCCGTCTCTCTCCACATGCATCA
GCAGATCCTAAGCCGACAACAGAGCTTAGGTTCAGCCTTTGGACACAGCCCTCCACTCATCCACCCTGCCCCAACTTTTCCAACACAGAG
GCCTATTCCAGGGATCCCTACGGTTCTGAACCCCGTCCAGGTCAGCTCCGGCCCTTCTGAGTCCTCACAGAACAAGCCCACGAGTGAGTC
TGCAGTGAGCAGCACTGGTGACCCGATGCACAACAAGAGGTCCAAGATCAAACCCGATGAAGACCTCCCCAGCCCAGGGGCTCGGGGGCA
GCAGGAACAGCCCGAAGGAACAACCCTTGTCAAGGAGGAAGGGGACAAAGATGAAAGCAAACAGGAGCCTGAAGTCATCTATGAGACAAA
CTGCCACTGGGAAGGCTGCGCGAGGGAGTTCGACACCCAAGAGCAGCTTGTGCACCATATAAATAACGACCATATTCATGGAGAGAAGAA
GGAGTTCGTGTGCAGGTGGCTGGACTGCTCAAGAGAGCAGAAACCCTTCAAAGCCCAGTATATGTTGGTAGTGCATATGAGAAGACACAC
GGGCGAGAAGCCTCACAAATGCACTTTTGAAGGTTGCACAAAGGCCTACTCGAGACTAGAAAACTTGAAAACACACTTGAGATCTCACAC
TGGAGAGAAACCATACGTCTGTGAGCACGAAGGTTGCAACAAGGCTTTCTCAAATGCCTCTGATCGCGCCAAACACCAAAACAGAACGCA
TTCCAATGAGAAACCATATGTGTGCAAAATCCCAGGCTGCACTAAGCGTTACACAGACCCAAGCTCCCTCCGGAAACATGTGAAGACAGT
GCATGGCCCAGAGGCTCATGTCACCAAGAAGCAGCGAGGGGACATCCATCCTCGGCCGCCACCCCCGAGAGATTCCGGCAGCCATTCACA
GTCCAGGTCGCCTGGCCGACCGACTCAGGGAGCCCTTGGTGAGCAGCAGGACCTCAGCAACACTACCTCAAAGCGGGAAGAATGCCTCCA
GGTGAAAACCGTCAAGGCAGAGAAGCCAATGACATCTCAGCCAAGCCCTGGTGGTCAGTCTTCATGCAGCAGCCAACAGTCCCCCATCAG
CAACTATTCCAACAGTGGGCTCGAGCTTCCTCTGACCGATGGAGGTAGTATAGGAGACCTCAGTGCCATCGATGAAACCCCAATCATGGA
CTCAACCATTTCCACTGCAACCACAGCCCTTGCTTTGCAAGCCAGGAGAAACCCGGCAGGGACCAAATGGATGGAGCACGTAAAACTAGA
AAGGCTAAAACAAGTGAATGGAATGTTTCCGCGACTGAACCCCATTCTACCCCCTAAAGCCCCTGCGGTCTCTCCTCTCATAGGAAATGG
CACACAGTCCAACAACACCTGCAGCTTGGGTGGGCCCATGACGCTTCTCCCGGGCAGAAGCGACCTCTCTGGGGTGGACGTCACTATGCT
GAACATGCTCAACAGAAGGGACAGCAGCGCCAGCACCATCAGCTCGGCCTACCTGAGCAGCCGCCGCTCCTCAGGGATCTCGCCCTGCTT
CTCCAGCCGCCGCTCCAGCGAGGCGTCACAGGCCGAGGGCCGGCCGCAGAACGTGAGCGTGGCCGACTCCTACGACCCCATCTCCACCGA
CGCCTCGCGCCGCTCCAGCGAAGCCAGCCAGAGCGACGGCCTGCCCAGCCTGCTCAGCCTCACGCCCGCCCAGCAGTACCGCCTCAAGGC
CAAGTACGCGGCTGCCACAGGAGGGCCGCCGCCGACGCCCCTGCCCAACATGGAGAGGATGAGCCTGAAGACGCGCCTGGCGCTGCTCGG
GGATGCCCTCGAGCCTGGCGTGGCCCTGCCTCCAGTTCATGCCCCGAGGAGGTGCAGCGACGGGGGAGCCCACGGCTACGGGCGGCGCCA
CCTGCAGCCGCACGATGCGCCGGGCCACGGCGTGAGGAGGGCCAGCGACCCGGTGCGGACAGGCTCCGAGGGCCTGGCCCTGCCTCGTGT
GCCGCGCTTCAGCAGCCTCAGCAGCTGCAACCCCCCGGCGATGGCCACGTCCGCGGAGAAGCGCAGTCTCGTGCTTCAGAATTACACGCG
GCCCGAGGGCGGCCAGTCCCGAAACTTCCACTCGTCCCCCTGTCCTCCCAGCATCACCGAGAACGTCACCCTGGAGTCCCTGACCATGGA
CGCTGATGCCAACCTGAACGATGAGGATTTCCTGCCGGACGACGTGGTGCAGTATTTAAATTCCCAGAACCAAGCAGGGTACGAGCAGCA
CTTCCCCAGCGCCCTCCCGGACGACAGCAAAGTGCCCCACGGGCCCGGTGACTTTGACGCGCCCGGGCTGCCAGACAGCCACGCTGGCCA
GCAGTTCCATGCCCTCGAGCAGCCCTGCCCCGAGGGCAGCAAAACCGACCTGCCCATTCAGTGGAACGAAGTCAGCTCCGGAAGCGCCGA
CCTGTCCTCCTCCAAGCTCAAGTGTGGGCCGCGGCCCGCTGTGCCGCAGACTCGCGCCTTTGGGTTCTGCAACGGCATGGTCGTCCACCC
GCAGAACCCCTTGAGGAGCGGGCCTGCTGGGGGCTATCAGACCCTCGGGGAGAACAGCAACCCCTACGGTGGCCCAGAGCACTTGATGCT
CCACAACAGCCCCGGAAGTGGCACCAGTGGAAACGCCTTCCATGAACAGCCCTGTAAGGCCCCGCAGTATGGGAACTGTCTCAACAGGCA
GCCAGTGGCCCCTGGTGCACTCGACGGTGCCTGTGGTGCCGGGATTCAAGCCTCAAAGCTGAAGAGCACCCCCATGCAAGGGAGCGGGGG
CCAGCTGAATTTCGGCCTGCCGGTAGCGCCAAATGAGTCAGCTGGCAGCATGGTGAATGGCATGCAGAACCAGGACCCAGTGGGACAGGG
GTACCTGGCTCACCAGCTCCTCGGCGACAGCATGCAGCACCCGGGGGCAGGCCGCCCCGGTCAGCAGATGCTTGGGCAGATTAGTGCTAC
CTCACACATCAACATCTACCAAGGGCCAGAGAGCTGCCTGCCAGGGGCTCACGGCATGGGCAGCCAGCCGTCAAGCTTGGCAGTTGTCAG
GGGCTACCAGCCATGTGCCAGCTTTGGGGGCAGCAGGCGCCAGGCTATGCCGAGGGACAGCCTTGCTCTGCAGTCAGGACAGCTCAGTGA
CACAAGTCAGACCTGCAGGGTGAATGGTATCAAGATGGAGATGAAAGGGCAGCCCCATCCGCTGTGCTCTAATCTGCAGAATTACTCTGG
TCAGTTCTATGACCAAACCGTGGGCTTCAGTCAGCAAGACACGAAAGCTGGTTCATTCTCTATTTCAGACGCCAGCTGCCTGCTACAGGG
GACCAGCGCCAAAAACTCTGAGTTACTTTCCCCAGGTGCTAATCAGGTGACAAGCACAGTGGACAGCCTCGACAGCCATGACCTGGAAGG
GGTACAGATTGACTTCGATGCCATCATAGACGATGGGGACCACTCCAGCCTGATGTCGGGGGCCCTGAGCCCAAGTATCATTCAGAACCT
TTCCCATAGCTCCTCCCGCCTCACCACGCCTCGGGCGTCCCTCCCATTCCCAGCGCTGTCCATGAGCACCACCAACATGGCTATCGGGGA
CATGAGTTCTTTGCTGACCTCCCTAGCGGAAGAAAGCAAATTCCTTGCAGTTATGCAATAGGCTTTAGGAAAAAAAGACTGCAACCAACG
GAAATCAATAGGAGTTGAAGAGATTAAACTGACTTTGTTTTGGCTGTTTTTTTAGTTCTGTATGTATTTTAGCAATCTCATCTCACCTAA
CTGAGATGTGTTTCAATTATATTCCTTTTATGGAAAAGGACTCTGAAAAACCCTAAAGTATTCTAGGGAGAAACTGTCTTCCATTTCAGT
TTTGAATCAGTATTGTTACACTCAAACCACCCTCTTTTTAAAAAAAAAAAAAAAAACTGTAAGCCCCGCCCCCTTTTTAGTAAACCGATG
TAAATTTGTGATGTGCATATTCTTCTTTCTTTTAGAAGAGCAGTCAAATTAAAGGATTTGACATGTTTTGCTGTTGCTCAAAGGAAATAG
GAGTTGGTGTGCTTGTGACCAAGGGGTTACACTTCCAGCTTTTAAAATTCTCCTTTACATGTGCTCAGTGTTTTGTTTTGTGTTTTGGTT
TCTGTTTTTTATTTTAATTCCCACATTGGGCACAAGAATCAGAATATGGATAGCTAGTTTAAGAAACTTTTGTGGGTGCACTGTAGCATA
GATGACAGAATATTGATGTTCCCCCCATCTCCAATTCAGTTCAGGGCATTCCACAGTTAAACAGAAATGGGAACGTGGGGCTCTTATAAA
TGAAATGGGCGCTCACAGTTTTGGTTTTCAGCTCTTCATGTCTGTAAGTGTGCTTTGGGGGAGGCTATGTCTGTATGGTCGATTCTCAGT
TATCACATTTGCCTCTCCTCCCACTACCTTCATGAACATTCAGTGCTGTTTCGCACTGCAGTTAGAGAGAAGGGACGGACAGTTGGTGAC
ACTCAGCCACATTGCTACTTTTATCTGTTCTGGTAAGAAGTTAGATAGATGGTAGATTGAAGCAATTGGGTAGAATTAGTTGGGGGAATA
TTTATGAGTTGCTGTGTTTGTTGATTAGTTCCATCTCTTTCCCATTTTAACTGAGAATTGATTATATATAGCTCTAAGTATATAGGTATT
TAAACAACCCCACAAGCGGCTGTATCAGTAACATTTATTAATTCCACTATAGTGAGGGAGGATTTCCATTCTAAATACCTTATTTTGAGG
GATTTATAAAACTTAGTTGTAAAAGAGAAAGCCCACATAGTGGGAATAAATTGCTTCAGCCATTTTTAGTATTTGAGAGCACTAGGGAAG
ATGTTTAGTAGCTGTGTGGATGCCTTTTTTCACACCCTGTCTATTGAATGCTGCATCCATTCACGAAGTTAAATGTTACATGCAGTTAGT
CCTTAATGTGGACTGGATCTGTACTTTTGTTTTGGATTAAAACATTTAAAGATTTTTGAAGTGCAGCTACTCCCCACGTGCATTTGATAC
ACATAAAAGTCATACTGTGTGTGCACAAAGAGTACATGGATTTTCCAGCATATTGCTTTAAAAAATTATATAAACTGTTAAAATATTAAC
ACCTCAGGCTACCTGCTGTATTCTGTCCCATTGACCCCTGGAATTGGATTTACTGCAAGTGATTGATAATTCAATTATGTGGCTTTTCCC
CTTTAATCTTGCCATTTAAATTACAGTAGAAAGACAAAATCAAGTAAAATAAAGTGTTAGATAATAGAAAGAGTGTTAAGACCAGCCCAC
TTTTCTCATGTTTATGTTCTTTCATTTGGACCAAGAATCTCCGCATGGAGGTTGATTTGCCACTGGGGACTTTGGCTAAGACTATTAGGT
TTGCTTTCAACTAGATGTTCCTGAGACAAGCAGAGGGACACTGCAATTCCCCTTCCATGCCTGCTGTTCTCCCCCATGTAAGTCTTCTTT
GAAATTAACGGATGTGTCTCCTTTGGAACAGCCCCATAACAAAAGAGAACTACTGATCTGAGCATAGGAAAGTAGAGGCTCTACCACTTT
TCAGTTGAAAAAGCAAGACTTTCTCTGTGTTTCTGAAACAAGGCATAATGTTGTCACAGAATCAGAGATCCAGTCTCACTTTTCCACAAA
TCTCCAAATCTCCAGTCTTATCTTGTGTGCTCTAATGGTTTGGTTCAATCCCTTTCCAACTCTTGTTTTCAAAGCATGGGGCCTGAGTGT
TCTCCACTCCTCCTAAGAAAGGAGCTTGGGTGGAAGGGACCATGCTGACCTCCTCCATCAGAGGGCTCTTCCAGTAGTATTCTCGGATGC
AACCTCCATTTCTCAGTTACCATTATTTCCTGTATCAGCTTTGTCCTTCCTGGAGGGATGCACAGTGATCCGGCCCACCACTGTTGTTGT
CTTGTGCTTCTGCTCTTTCCTATGGTTTCAGGTTATTTTCTGGGTTTCCCCTATTCTTCTTTTATTTCTTTTTTTTTTTATATTTGCTTT
CCTTTCTACTGCTTTTAGATTTGCAGGAGATGCAAGTTTCAGCTCAATGTTTGGCTTCTCTCAATATGGAAATTTCAGAAGGACAGAGGA
GAGGAGGGAGGAAGAAGAAAGTATACTCCTCCAGAATTTCAGTGATCTGTTGTGGCAGTCCAGTGGAAGGAAGGTCTTTTGAGGTCACTT
AGAAGCATCTTTTTGGGACATCCTTTTGGGATCTCTGTAGGCTAGGCATCTCATATCTTGAGACTCACCCCCAGCCTCCAAGCCTCTCTC
CATTTCTCTAACCTATGCATTTTAGAGCGAGAGGACCGCCTCACTAGTGTCACCATCCTGCCTTTTCTAAAACATGCAGGCTCACACATT
CTACTCCTGCTTAATGTCTGTGTTAAACGTTTTCTAACCATTTTTGTTTTATTTTTCTGAAAAAGTTAACCCCTCCCAACTCCTCACACA
TTGGCTCTTCCTCTTGAGCCACAAAGTTTTGATTCTTGCGATGTATGTGCCTTATTTTATGTTAATCTTGTCAATGAGAGGGACCAGTTG
GTGTTGCCCAATCAGCACTCCAAGGCTGTGTGTGCACCAGCCAGAGAGCGCACGGTGGTAGCAGAGTCGAGGCTGTCTTGTATCCTGGTT
TCATGTGTTGTTTTGAACTGATAGGAGGATGTTCTCTTCTGACAAGTTACCCTTGTGTATCCTGCAGACATGTAAAATAAAATACAAGTT
CATTTTTTTCACCTTTTTTAGATTTTTTTAAAAAATAAAATGTGTAATCCTTTTTTTAAAAGAAACACATGTAAATACATTTAAGTATTG
TAGGCATAGCGTTCAGATGTGACTGGCCCAGGCGTTCCTCGGACAAGCCTGCATTCCCCGTGATCACGCCCACCTCAAGCCCAGGGGCTG
CAGCCCAGCCACAGATGAACTCTACCTTTGCTTTCAGAACCACTTAGTCCTTTTGTAACAAAGAAAAAAAAATGTTTCTTACAATGTCAA

>80496_80496_2_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000399034_GLI3_chr7_42116456_ENST00000395925_length(amino acids)=1541AA_BP=83
MRNRRRRLWRIGGLRSAGAGRGGGEGMSVSARSAAAEERSVNSSTMEVAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVDPPHLFP
AFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISAT
RGLSPTDAPHAGVSPAEYYHQMALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLSDHSFDLQTM
IRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTV
LNPVQVSSGPSESSQNKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYETNCHWEGCAR
EFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCE
HEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPT
QGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATT
ALALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTMLNMLNRRDS
SASTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPISTDASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAATGG
PPPTPLPNMERMSLKTRLALLGDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGVRRASDPVRTGSEGLALPRVPRFSSLSS
CNPPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTMDADANLNDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDD
SKVPHGPGDFDAPGLPDSHAGQQFHALEQPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVHPQNPLRSGP
AGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNRQPVAPGALDGACGAGIQASKLKSTPMQGSGGQLNFGLPV
APNESAGSMVNGMQNQDPVGQGYLAHQLLGDSMQHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAHGMGSQPSSLAVVRGYQPCASF
GGSRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPLCSNLQNYSGQFYDQTVGFSQQDTKAGSFSISDASCLLQGTSAKNSEL
LSPGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIGDMSSLLTSL

--------------------------------------------------------------
>80496_80496_3_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000399035_GLI3_chr7_42116456_ENST00000395925_length(transcript)=7922nt_BP=166nt
ATGTCGGTCAGTGCGAGATCCGCTGCTGCTGAGGAGAGGAGCGTCAACAGCAGCACCATGGTACAACAGAAGAACCTTGAAGGCTATGTG
GGATTTGCCAATCTCCCAAATCAAGTATACAGAAAATCGGTGAAGAGAGGTTTTGAATTCACGCTTATGGTAGTGGACCCTCCTCATCTT
TTCCCTGCCTTCCATCCTCCTGTACCAATTGATGCCAGACATCATGAGGGCCGTTACCATTACGATCCATCTCCGATTCCTCCATTGCAT
ATGACTTCCGCCTTATCTAGTAGCCCTACGTATCCGGACCTGCCCTTCATTAGGATCTCCCCACACCGGAACCCCACTGCTGCTTCCGAG
TCTCCCTTCAGCCCTCCACATCCCTACATTAATCCCTACATGGACTATATCCGCTCCTTGCACAGCAGCCCATCGCTCTCCATGATCTCA
GCAACCCGTGGGCTGAGCCCTACAGATGCGCCCCATGCAGGAGTCAGCCCAGCAGAATACTATCATCAGATGGCCCTGCTAACTGGCCAG
CGCAGCCCCTATGCAGACATTATTCCCTCAGCTGCCACCGCCGGCACGGGGGCCATCCACATGGAATATCTTCATGCTATGGATAGCACC
AGATTCTCCAGCCCCAGGCTGTCAGCCAGGCCGAGCCGAAAACGTACACTGTCCATATCACCACTCTCCGATCATAGCTTTGACCTTCAG
ACCATGATAAGGACGTCTCCCAACTCCTTGGTCACGATTCTCAATAATTCCCGTAGCAGCTCTTCAGCAAGTGGCTCCTATGGTCACTTA
TCTGCAAGTGCAATCAGCCCTGCCTTGAGCTTCACCTACTCTTCCGCGCCCGTCTCTCTCCACATGCATCAGCAGATCCTAAGCCGACAA
CAGAGCTTAGGTTCAGCCTTTGGACACAGCCCTCCACTCATCCACCCTGCCCCAACTTTTCCAACACAGAGGCCTATTCCAGGGATCCCT
ACGGTTCTGAACCCCGTCCAGGTCAGCTCCGGCCCTTCTGAGTCCTCACAGAACAAGCCCACGAGTGAGTCTGCAGTGAGCAGCACTGGT
GACCCGATGCACAACAAGAGGTCCAAGATCAAACCCGATGAAGACCTCCCCAGCCCAGGGGCTCGGGGGCAGCAGGAACAGCCCGAAGGA
ACAACCCTTGTCAAGGAGGAAGGGGACAAAGATGAAAGCAAACAGGAGCCTGAAGTCATCTATGAGACAAACTGCCACTGGGAAGGCTGC
GCGAGGGAGTTCGACACCCAAGAGCAGCTTGTGCACCATATAAATAACGACCATATTCATGGAGAGAAGAAGGAGTTCGTGTGCAGGTGG
CTGGACTGCTCAAGAGAGCAGAAACCCTTCAAAGCCCAGTATATGTTGGTAGTGCATATGAGAAGACACACGGGCGAGAAGCCTCACAAA
TGCACTTTTGAAGGTTGCACAAAGGCCTACTCGAGACTAGAAAACTTGAAAACACACTTGAGATCTCACACTGGAGAGAAACCATACGTC
TGTGAGCACGAAGGTTGCAACAAGGCTTTCTCAAATGCCTCTGATCGCGCCAAACACCAAAACAGAACGCATTCCAATGAGAAACCATAT
GTGTGCAAAATCCCAGGCTGCACTAAGCGTTACACAGACCCAAGCTCCCTCCGGAAACATGTGAAGACAGTGCATGGCCCAGAGGCTCAT
GTCACCAAGAAGCAGCGAGGGGACATCCATCCTCGGCCGCCACCCCCGAGAGATTCCGGCAGCCATTCACAGTCCAGGTCGCCTGGCCGA
CCGACTCAGGGAGCCCTTGGTGAGCAGCAGGACCTCAGCAACACTACCTCAAAGCGGGAAGAATGCCTCCAGGTGAAAACCGTCAAGGCA
GAGAAGCCAATGACATCTCAGCCAAGCCCTGGTGGTCAGTCTTCATGCAGCAGCCAACAGTCCCCCATCAGCAACTATTCCAACAGTGGG
CTCGAGCTTCCTCTGACCGATGGAGGTAGTATAGGAGACCTCAGTGCCATCGATGAAACCCCAATCATGGACTCAACCATTTCCACTGCA
ACCACAGCCCTTGCTTTGCAAGCCAGGAGAAACCCGGCAGGGACCAAATGGATGGAGCACGTAAAACTAGAAAGGCTAAAACAAGTGAAT
GGAATGTTTCCGCGACTGAACCCCATTCTACCCCCTAAAGCCCCTGCGGTCTCTCCTCTCATAGGAAATGGCACACAGTCCAACAACACC
TGCAGCTTGGGTGGGCCCATGACGCTTCTCCCGGGCAGAAGCGACCTCTCTGGGGTGGACGTCACTATGCTGAACATGCTCAACAGAAGG
GACAGCAGCGCCAGCACCATCAGCTCGGCCTACCTGAGCAGCCGCCGCTCCTCAGGGATCTCGCCCTGCTTCTCCAGCCGCCGCTCCAGC
GAGGCGTCACAGGCCGAGGGCCGGCCGCAGAACGTGAGCGTGGCCGACTCCTACGACCCCATCTCCACCGACGCCTCGCGCCGCTCCAGC
GAAGCCAGCCAGAGCGACGGCCTGCCCAGCCTGCTCAGCCTCACGCCCGCCCAGCAGTACCGCCTCAAGGCCAAGTACGCGGCTGCCACA
GGAGGGCCGCCGCCGACGCCCCTGCCCAACATGGAGAGGATGAGCCTGAAGACGCGCCTGGCGCTGCTCGGGGATGCCCTCGAGCCTGGC
GTGGCCCTGCCTCCAGTTCATGCCCCGAGGAGGTGCAGCGACGGGGGAGCCCACGGCTACGGGCGGCGCCACCTGCAGCCGCACGATGCG
CCGGGCCACGGCGTGAGGAGGGCCAGCGACCCGGTGCGGACAGGCTCCGAGGGCCTGGCCCTGCCTCGTGTGCCGCGCTTCAGCAGCCTC
AGCAGCTGCAACCCCCCGGCGATGGCCACGTCCGCGGAGAAGCGCAGTCTCGTGCTTCAGAATTACACGCGGCCCGAGGGCGGCCAGTCC
CGAAACTTCCACTCGTCCCCCTGTCCTCCCAGCATCACCGAGAACGTCACCCTGGAGTCCCTGACCATGGACGCTGATGCCAACCTGAAC
GATGAGGATTTCCTGCCGGACGACGTGGTGCAGTATTTAAATTCCCAGAACCAAGCAGGGTACGAGCAGCACTTCCCCAGCGCCCTCCCG
GACGACAGCAAAGTGCCCCACGGGCCCGGTGACTTTGACGCGCCCGGGCTGCCAGACAGCCACGCTGGCCAGCAGTTCCATGCCCTCGAG
CAGCCCTGCCCCGAGGGCAGCAAAACCGACCTGCCCATTCAGTGGAACGAAGTCAGCTCCGGAAGCGCCGACCTGTCCTCCTCCAAGCTC
AAGTGTGGGCCGCGGCCCGCTGTGCCGCAGACTCGCGCCTTTGGGTTCTGCAACGGCATGGTCGTCCACCCGCAGAACCCCTTGAGGAGC
GGGCCTGCTGGGGGCTATCAGACCCTCGGGGAGAACAGCAACCCCTACGGTGGCCCAGAGCACTTGATGCTCCACAACAGCCCCGGAAGT
GGCACCAGTGGAAACGCCTTCCATGAACAGCCCTGTAAGGCCCCGCAGTATGGGAACTGTCTCAACAGGCAGCCAGTGGCCCCTGGTGCA
CTCGACGGTGCCTGTGGTGCCGGGATTCAAGCCTCAAAGCTGAAGAGCACCCCCATGCAAGGGAGCGGGGGCCAGCTGAATTTCGGCCTG
CCGGTAGCGCCAAATGAGTCAGCTGGCAGCATGGTGAATGGCATGCAGAACCAGGACCCAGTGGGACAGGGGTACCTGGCTCACCAGCTC
CTCGGCGACAGCATGCAGCACCCGGGGGCAGGCCGCCCCGGTCAGCAGATGCTTGGGCAGATTAGTGCTACCTCACACATCAACATCTAC
CAAGGGCCAGAGAGCTGCCTGCCAGGGGCTCACGGCATGGGCAGCCAGCCGTCAAGCTTGGCAGTTGTCAGGGGCTACCAGCCATGTGCC
AGCTTTGGGGGCAGCAGGCGCCAGGCTATGCCGAGGGACAGCCTTGCTCTGCAGTCAGGACAGCTCAGTGACACAAGTCAGACCTGCAGG
GTGAATGGTATCAAGATGGAGATGAAAGGGCAGCCCCATCCGCTGTGCTCTAATCTGCAGAATTACTCTGGTCAGTTCTATGACCAAACC
GTGGGCTTCAGTCAGCAAGACACGAAAGCTGGTTCATTCTCTATTTCAGACGCCAGCTGCCTGCTACAGGGGACCAGCGCCAAAAACTCT
GAGTTACTTTCCCCAGGTGCTAATCAGGTGACAAGCACAGTGGACAGCCTCGACAGCCATGACCTGGAAGGGGTACAGATTGACTTCGAT
GCCATCATAGACGATGGGGACCACTCCAGCCTGATGTCGGGGGCCCTGAGCCCAAGTATCATTCAGAACCTTTCCCATAGCTCCTCCCGC
CTCACCACGCCTCGGGCGTCCCTCCCATTCCCAGCGCTGTCCATGAGCACCACCAACATGGCTATCGGGGACATGAGTTCTTTGCTGACC
TCCCTAGCGGAAGAAAGCAAATTCCTTGCAGTTATGCAATAGGCTTTAGGAAAAAAAGACTGCAACCAACGGAAATCAATAGGAGTTGAA
GAGATTAAACTGACTTTGTTTTGGCTGTTTTTTTAGTTCTGTATGTATTTTAGCAATCTCATCTCACCTAACTGAGATGTGTTTCAATTA
TATTCCTTTTATGGAAAAGGACTCTGAAAAACCCTAAAGTATTCTAGGGAGAAACTGTCTTCCATTTCAGTTTTGAATCAGTATTGTTAC
ACTCAAACCACCCTCTTTTTAAAAAAAAAAAAAAAAACTGTAAGCCCCGCCCCCTTTTTAGTAAACCGATGTAAATTTGTGATGTGCATA
TTCTTCTTTCTTTTAGAAGAGCAGTCAAATTAAAGGATTTGACATGTTTTGCTGTTGCTCAAAGGAAATAGGAGTTGGTGTGCTTGTGAC
CAAGGGGTTACACTTCCAGCTTTTAAAATTCTCCTTTACATGTGCTCAGTGTTTTGTTTTGTGTTTTGGTTTCTGTTTTTTATTTTAATT
CCCACATTGGGCACAAGAATCAGAATATGGATAGCTAGTTTAAGAAACTTTTGTGGGTGCACTGTAGCATAGATGACAGAATATTGATGT
TCCCCCCATCTCCAATTCAGTTCAGGGCATTCCACAGTTAAACAGAAATGGGAACGTGGGGCTCTTATAAATGAAATGGGCGCTCACAGT
TTTGGTTTTCAGCTCTTCATGTCTGTAAGTGTGCTTTGGGGGAGGCTATGTCTGTATGGTCGATTCTCAGTTATCACATTTGCCTCTCCT
CCCACTACCTTCATGAACATTCAGTGCTGTTTCGCACTGCAGTTAGAGAGAAGGGACGGACAGTTGGTGACACTCAGCCACATTGCTACT
TTTATCTGTTCTGGTAAGAAGTTAGATAGATGGTAGATTGAAGCAATTGGGTAGAATTAGTTGGGGGAATATTTATGAGTTGCTGTGTTT
GTTGATTAGTTCCATCTCTTTCCCATTTTAACTGAGAATTGATTATATATAGCTCTAAGTATATAGGTATTTAAACAACCCCACAAGCGG
CTGTATCAGTAACATTTATTAATTCCACTATAGTGAGGGAGGATTTCCATTCTAAATACCTTATTTTGAGGGATTTATAAAACTTAGTTG
TAAAAGAGAAAGCCCACATAGTGGGAATAAATTGCTTCAGCCATTTTTAGTATTTGAGAGCACTAGGGAAGATGTTTAGTAGCTGTGTGG
ATGCCTTTTTTCACACCCTGTCTATTGAATGCTGCATCCATTCACGAAGTTAAATGTTACATGCAGTTAGTCCTTAATGTGGACTGGATC
TGTACTTTTGTTTTGGATTAAAACATTTAAAGATTTTTGAAGTGCAGCTACTCCCCACGTGCATTTGATACACATAAAAGTCATACTGTG
TGTGCACAAAGAGTACATGGATTTTCCAGCATATTGCTTTAAAAAATTATATAAACTGTTAAAATATTAACACCTCAGGCTACCTGCTGT
ATTCTGTCCCATTGACCCCTGGAATTGGATTTACTGCAAGTGATTGATAATTCAATTATGTGGCTTTTCCCCTTTAATCTTGCCATTTAA
ATTACAGTAGAAAGACAAAATCAAGTAAAATAAAGTGTTAGATAATAGAAAGAGTGTTAAGACCAGCCCACTTTTCTCATGTTTATGTTC
TTTCATTTGGACCAAGAATCTCCGCATGGAGGTTGATTTGCCACTGGGGACTTTGGCTAAGACTATTAGGTTTGCTTTCAACTAGATGTT
CCTGAGACAAGCAGAGGGACACTGCAATTCCCCTTCCATGCCTGCTGTTCTCCCCCATGTAAGTCTTCTTTGAAATTAACGGATGTGTCT
CCTTTGGAACAGCCCCATAACAAAAGAGAACTACTGATCTGAGCATAGGAAAGTAGAGGCTCTACCACTTTTCAGTTGAAAAAGCAAGAC
TTTCTCTGTGTTTCTGAAACAAGGCATAATGTTGTCACAGAATCAGAGATCCAGTCTCACTTTTCCACAAATCTCCAAATCTCCAGTCTT
ATCTTGTGTGCTCTAATGGTTTGGTTCAATCCCTTTCCAACTCTTGTTTTCAAAGCATGGGGCCTGAGTGTTCTCCACTCCTCCTAAGAA
AGGAGCTTGGGTGGAAGGGACCATGCTGACCTCCTCCATCAGAGGGCTCTTCCAGTAGTATTCTCGGATGCAACCTCCATTTCTCAGTTA
CCATTATTTCCTGTATCAGCTTTGTCCTTCCTGGAGGGATGCACAGTGATCCGGCCCACCACTGTTGTTGTCTTGTGCTTCTGCTCTTTC
CTATGGTTTCAGGTTATTTTCTGGGTTTCCCCTATTCTTCTTTTATTTCTTTTTTTTTTTATATTTGCTTTCCTTTCTACTGCTTTTAGA
TTTGCAGGAGATGCAAGTTTCAGCTCAATGTTTGGCTTCTCTCAATATGGAAATTTCAGAAGGACAGAGGAGAGGAGGGAGGAAGAAGAA
AGTATACTCCTCCAGAATTTCAGTGATCTGTTGTGGCAGTCCAGTGGAAGGAAGGTCTTTTGAGGTCACTTAGAAGCATCTTTTTGGGAC
ATCCTTTTGGGATCTCTGTAGGCTAGGCATCTCATATCTTGAGACTCACCCCCAGCCTCCAAGCCTCTCTCCATTTCTCTAACCTATGCA
TTTTAGAGCGAGAGGACCGCCTCACTAGTGTCACCATCCTGCCTTTTCTAAAACATGCAGGCTCACACATTCTACTCCTGCTTAATGTCT
GTGTTAAACGTTTTCTAACCATTTTTGTTTTATTTTTCTGAAAAAGTTAACCCCTCCCAACTCCTCACACATTGGCTCTTCCTCTTGAGC
CACAAAGTTTTGATTCTTGCGATGTATGTGCCTTATTTTATGTTAATCTTGTCAATGAGAGGGACCAGTTGGTGTTGCCCAATCAGCACT
CCAAGGCTGTGTGTGCACCAGCCAGAGAGCGCACGGTGGTAGCAGAGTCGAGGCTGTCTTGTATCCTGGTTTCATGTGTTGTTTTGAACT
GATAGGAGGATGTTCTCTTCTGACAAGTTACCCTTGTGTATCCTGCAGACATGTAAAATAAAATACAAGTTCATTTTTTTCACCTTTTTT
AGATTTTTTTAAAAAATAAAATGTGTAATCCTTTTTTTAAAAGAAACACATGTAAATACATTTAAGTATTGTAGGCATAGCGTTCAGATG
TGACTGGCCCAGGCGTTCCTCGGACAAGCCTGCATTCCCCGTGATCACGCCCACCTCAAGCCCAGGGGCTGCAGCCCAGCCACAGATGAA
CTCTACCTTTGCTTTCAGAACCACTTAGTCCTTTTGTAACAAAGAAAAAAAAATGTTTCTTACAATGTCAATAAAAAATTCTTTGTATGG

>80496_80496_3_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000399035_GLI3_chr7_42116456_ENST00000395925_length(amino acids)=1513AA_BP=55
MSVSARSAAAEERSVNSSTMVQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVDPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLH
MTSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISATRGLSPTDAPHAGVSPAEYYHQMALLTGQ
RSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHL
SASAISPALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSESAVSSTG
DPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYETNCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRW
LDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPY
VCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKA
EKPMTSQPSPGGQSSCSSQQSPISNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHVKLERLKQVN
GMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTMLNMLNRRDSSASTISSAYLSSRRSSGISPCFSSRRSS
EASQAEGRPQNVSVADSYDPISTDASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRLALLGDALEPG
VALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGVRRASDPVRTGSEGLALPRVPRFSSLSSCNPPAMATSAEKRSLVLQNYTRPEGGQS
RNFHSSPCPPSITENVTLESLTMDADANLNDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGLPDSHAGQQFHALE
QPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVHPQNPLRSGPAGGYQTLGENSNPYGGPEHLMLHNSPGS
GTSGNAFHEQPCKAPQYGNCLNRQPVAPGALDGACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNESAGSMVNGMQNQDPVGQGYLAHQL
LGDSMQHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAHGMGSQPSSLAVVRGYQPCASFGGSRRQAMPRDSLALQSGQLSDTSQTCR
VNGIKMEMKGQPHPLCSNLQNYSGQFYDQTVGFSQQDTKAGSFSISDASCLLQGTSAKNSELLSPGANQVTSTVDSLDSHDLEGVQIDFD

--------------------------------------------------------------
>80496_80496_4_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000435235_GLI3_chr7_42116456_ENST00000395925_length(transcript)=8198nt_BP=442nt
AAGTCATGCTCGAAATGGAGCGAGGCGGCGGAGCTGGGGAGGCGGTAATCTCGCGAGATGGAAGCCAGCCTCCGCTAGGCCCGGAAGCCT
CGTCTGAGGGGGCGGGGGACGGAGGAGGGAGCGGGAGTCGAGCGAGAGCCTGTGGAGGAGTCCGCCTGCTGTAGCGTGCGTAAGCAAGGC
AGCTACGCCGGGCGGCTACGCTGCGGAATCGGCGTAGGCGCCTTTGGAGAATCGGCGGGCTGCGCTCCGCTGGGGCTGGTCGCGGAGGGG
GGGAGGGGATGTCGGTCAGTGCGAGATCCGCTGCTGCTGAGGAGAGGAGCGTCAACAGCAGCACCATGGCAACAGAAGAACCTTGAAGGC
TATGTGGGATTTGCCAATCTCCCAAATCAAGTATACAGAAAATCGGTGAAGAGAGGTTTTGAATTCACGCTTATGGTAGTGGACCCTCCT
CATCTTTTCCCTGCCTTCCATCCTCCTGTACCAATTGATGCCAGACATCATGAGGGCCGTTACCATTACGATCCATCTCCGATTCCTCCA
TTGCATATGACTTCCGCCTTATCTAGTAGCCCTACGTATCCGGACCTGCCCTTCATTAGGATCTCCCCACACCGGAACCCCACTGCTGCT
TCCGAGTCTCCCTTCAGCCCTCCACATCCCTACATTAATCCCTACATGGACTATATCCGCTCCTTGCACAGCAGCCCATCGCTCTCCATG
ATCTCAGCAACCCGTGGGCTGAGCCCTACAGATGCGCCCCATGCAGGAGTCAGCCCAGCAGAATACTATCATCAGATGGCCCTGCTAACT
GGCCAGCGCAGCCCCTATGCAGACATTATTCCCTCAGCTGCCACCGCCGGCACGGGGGCCATCCACATGGAATATCTTCATGCTATGGAT
AGCACCAGATTCTCCAGCCCCAGGCTGTCAGCCAGGCCGAGCCGAAAACGTACACTGTCCATATCACCACTCTCCGATCATAGCTTTGAC
CTTCAGACCATGATAAGGACGTCTCCCAACTCCTTGGTCACGATTCTCAATAATTCCCGTAGCAGCTCTTCAGCAAGTGGCTCCTATGGT
CACTTATCTGCAAGTGCAATCAGCCCTGCCTTGAGCTTCACCTACTCTTCCGCGCCCGTCTCTCTCCACATGCATCAGCAGATCCTAAGC
CGACAACAGAGCTTAGGTTCAGCCTTTGGACACAGCCCTCCACTCATCCACCCTGCCCCAACTTTTCCAACACAGAGGCCTATTCCAGGG
ATCCCTACGGTTCTGAACCCCGTCCAGGTCAGCTCCGGCCCTTCTGAGTCCTCACAGAACAAGCCCACGAGTGAGTCTGCAGTGAGCAGC
ACTGGTGACCCGATGCACAACAAGAGGTCCAAGATCAAACCCGATGAAGACCTCCCCAGCCCAGGGGCTCGGGGGCAGCAGGAACAGCCC
GAAGGAACAACCCTTGTCAAGGAGGAAGGGGACAAAGATGAAAGCAAACAGGAGCCTGAAGTCATCTATGAGACAAACTGCCACTGGGAA
GGCTGCGCGAGGGAGTTCGACACCCAAGAGCAGCTTGTGCACCATATAAATAACGACCATATTCATGGAGAGAAGAAGGAGTTCGTGTGC
AGGTGGCTGGACTGCTCAAGAGAGCAGAAACCCTTCAAAGCCCAGTATATGTTGGTAGTGCATATGAGAAGACACACGGGCGAGAAGCCT
CACAAATGCACTTTTGAAGGTTGCACAAAGGCCTACTCGAGACTAGAAAACTTGAAAACACACTTGAGATCTCACACTGGAGAGAAACCA
TACGTCTGTGAGCACGAAGGTTGCAACAAGGCTTTCTCAAATGCCTCTGATCGCGCCAAACACCAAAACAGAACGCATTCCAATGAGAAA
CCATATGTGTGCAAAATCCCAGGCTGCACTAAGCGTTACACAGACCCAAGCTCCCTCCGGAAACATGTGAAGACAGTGCATGGCCCAGAG
GCTCATGTCACCAAGAAGCAGCGAGGGGACATCCATCCTCGGCCGCCACCCCCGAGAGATTCCGGCAGCCATTCACAGTCCAGGTCGCCT
GGCCGACCGACTCAGGGAGCCCTTGGTGAGCAGCAGGACCTCAGCAACACTACCTCAAAGCGGGAAGAATGCCTCCAGGTGAAAACCGTC
AAGGCAGAGAAGCCAATGACATCTCAGCCAAGCCCTGGTGGTCAGTCTTCATGCAGCAGCCAACAGTCCCCCATCAGCAACTATTCCAAC
AGTGGGCTCGAGCTTCCTCTGACCGATGGAGGTAGTATAGGAGACCTCAGTGCCATCGATGAAACCCCAATCATGGACTCAACCATTTCC
ACTGCAACCACAGCCCTTGCTTTGCAAGCCAGGAGAAACCCGGCAGGGACCAAATGGATGGAGCACGTAAAACTAGAAAGGCTAAAACAA
GTGAATGGAATGTTTCCGCGACTGAACCCCATTCTACCCCCTAAAGCCCCTGCGGTCTCTCCTCTCATAGGAAATGGCACACAGTCCAAC
AACACCTGCAGCTTGGGTGGGCCCATGACGCTTCTCCCGGGCAGAAGCGACCTCTCTGGGGTGGACGTCACTATGCTGAACATGCTCAAC
AGAAGGGACAGCAGCGCCAGCACCATCAGCTCGGCCTACCTGAGCAGCCGCCGCTCCTCAGGGATCTCGCCCTGCTTCTCCAGCCGCCGC
TCCAGCGAGGCGTCACAGGCCGAGGGCCGGCCGCAGAACGTGAGCGTGGCCGACTCCTACGACCCCATCTCCACCGACGCCTCGCGCCGC
TCCAGCGAAGCCAGCCAGAGCGACGGCCTGCCCAGCCTGCTCAGCCTCACGCCCGCCCAGCAGTACCGCCTCAAGGCCAAGTACGCGGCT
GCCACAGGAGGGCCGCCGCCGACGCCCCTGCCCAACATGGAGAGGATGAGCCTGAAGACGCGCCTGGCGCTGCTCGGGGATGCCCTCGAG
CCTGGCGTGGCCCTGCCTCCAGTTCATGCCCCGAGGAGGTGCAGCGACGGGGGAGCCCACGGCTACGGGCGGCGCCACCTGCAGCCGCAC
GATGCGCCGGGCCACGGCGTGAGGAGGGCCAGCGACCCGGTGCGGACAGGCTCCGAGGGCCTGGCCCTGCCTCGTGTGCCGCGCTTCAGC
AGCCTCAGCAGCTGCAACCCCCCGGCGATGGCCACGTCCGCGGAGAAGCGCAGTCTCGTGCTTCAGAATTACACGCGGCCCGAGGGCGGC
CAGTCCCGAAACTTCCACTCGTCCCCCTGTCCTCCCAGCATCACCGAGAACGTCACCCTGGAGTCCCTGACCATGGACGCTGATGCCAAC
CTGAACGATGAGGATTTCCTGCCGGACGACGTGGTGCAGTATTTAAATTCCCAGAACCAAGCAGGGTACGAGCAGCACTTCCCCAGCGCC
CTCCCGGACGACAGCAAAGTGCCCCACGGGCCCGGTGACTTTGACGCGCCCGGGCTGCCAGACAGCCACGCTGGCCAGCAGTTCCATGCC
CTCGAGCAGCCCTGCCCCGAGGGCAGCAAAACCGACCTGCCCATTCAGTGGAACGAAGTCAGCTCCGGAAGCGCCGACCTGTCCTCCTCC
AAGCTCAAGTGTGGGCCGCGGCCCGCTGTGCCGCAGACTCGCGCCTTTGGGTTCTGCAACGGCATGGTCGTCCACCCGCAGAACCCCTTG
AGGAGCGGGCCTGCTGGGGGCTATCAGACCCTCGGGGAGAACAGCAACCCCTACGGTGGCCCAGAGCACTTGATGCTCCACAACAGCCCC
GGAAGTGGCACCAGTGGAAACGCCTTCCATGAACAGCCCTGTAAGGCCCCGCAGTATGGGAACTGTCTCAACAGGCAGCCAGTGGCCCCT
GGTGCACTCGACGGTGCCTGTGGTGCCGGGATTCAAGCCTCAAAGCTGAAGAGCACCCCCATGCAAGGGAGCGGGGGCCAGCTGAATTTC
GGCCTGCCGGTAGCGCCAAATGAGTCAGCTGGCAGCATGGTGAATGGCATGCAGAACCAGGACCCAGTGGGACAGGGGTACCTGGCTCAC
CAGCTCCTCGGCGACAGCATGCAGCACCCGGGGGCAGGCCGCCCCGGTCAGCAGATGCTTGGGCAGATTAGTGCTACCTCACACATCAAC
ATCTACCAAGGGCCAGAGAGCTGCCTGCCAGGGGCTCACGGCATGGGCAGCCAGCCGTCAAGCTTGGCAGTTGTCAGGGGCTACCAGCCA
TGTGCCAGCTTTGGGGGCAGCAGGCGCCAGGCTATGCCGAGGGACAGCCTTGCTCTGCAGTCAGGACAGCTCAGTGACACAAGTCAGACC
TGCAGGGTGAATGGTATCAAGATGGAGATGAAAGGGCAGCCCCATCCGCTGTGCTCTAATCTGCAGAATTACTCTGGTCAGTTCTATGAC
CAAACCGTGGGCTTCAGTCAGCAAGACACGAAAGCTGGTTCATTCTCTATTTCAGACGCCAGCTGCCTGCTACAGGGGACCAGCGCCAAA
AACTCTGAGTTACTTTCCCCAGGTGCTAATCAGGTGACAAGCACAGTGGACAGCCTCGACAGCCATGACCTGGAAGGGGTACAGATTGAC
TTCGATGCCATCATAGACGATGGGGACCACTCCAGCCTGATGTCGGGGGCCCTGAGCCCAAGTATCATTCAGAACCTTTCCCATAGCTCC
TCCCGCCTCACCACGCCTCGGGCGTCCCTCCCATTCCCAGCGCTGTCCATGAGCACCACCAACATGGCTATCGGGGACATGAGTTCTTTG
CTGACCTCCCTAGCGGAAGAAAGCAAATTCCTTGCAGTTATGCAATAGGCTTTAGGAAAAAAAGACTGCAACCAACGGAAATCAATAGGA
GTTGAAGAGATTAAACTGACTTTGTTTTGGCTGTTTTTTTAGTTCTGTATGTATTTTAGCAATCTCATCTCACCTAACTGAGATGTGTTT
CAATTATATTCCTTTTATGGAAAAGGACTCTGAAAAACCCTAAAGTATTCTAGGGAGAAACTGTCTTCCATTTCAGTTTTGAATCAGTAT
TGTTACACTCAAACCACCCTCTTTTTAAAAAAAAAAAAAAAAACTGTAAGCCCCGCCCCCTTTTTAGTAAACCGATGTAAATTTGTGATG
TGCATATTCTTCTTTCTTTTAGAAGAGCAGTCAAATTAAAGGATTTGACATGTTTTGCTGTTGCTCAAAGGAAATAGGAGTTGGTGTGCT
TGTGACCAAGGGGTTACACTTCCAGCTTTTAAAATTCTCCTTTACATGTGCTCAGTGTTTTGTTTTGTGTTTTGGTTTCTGTTTTTTATT
TTAATTCCCACATTGGGCACAAGAATCAGAATATGGATAGCTAGTTTAAGAAACTTTTGTGGGTGCACTGTAGCATAGATGACAGAATAT
TGATGTTCCCCCCATCTCCAATTCAGTTCAGGGCATTCCACAGTTAAACAGAAATGGGAACGTGGGGCTCTTATAAATGAAATGGGCGCT
CACAGTTTTGGTTTTCAGCTCTTCATGTCTGTAAGTGTGCTTTGGGGGAGGCTATGTCTGTATGGTCGATTCTCAGTTATCACATTTGCC
TCTCCTCCCACTACCTTCATGAACATTCAGTGCTGTTTCGCACTGCAGTTAGAGAGAAGGGACGGACAGTTGGTGACACTCAGCCACATT
GCTACTTTTATCTGTTCTGGTAAGAAGTTAGATAGATGGTAGATTGAAGCAATTGGGTAGAATTAGTTGGGGGAATATTTATGAGTTGCT
GTGTTTGTTGATTAGTTCCATCTCTTTCCCATTTTAACTGAGAATTGATTATATATAGCTCTAAGTATATAGGTATTTAAACAACCCCAC
AAGCGGCTGTATCAGTAACATTTATTAATTCCACTATAGTGAGGGAGGATTTCCATTCTAAATACCTTATTTTGAGGGATTTATAAAACT
TAGTTGTAAAAGAGAAAGCCCACATAGTGGGAATAAATTGCTTCAGCCATTTTTAGTATTTGAGAGCACTAGGGAAGATGTTTAGTAGCT
GTGTGGATGCCTTTTTTCACACCCTGTCTATTGAATGCTGCATCCATTCACGAAGTTAAATGTTACATGCAGTTAGTCCTTAATGTGGAC
TGGATCTGTACTTTTGTTTTGGATTAAAACATTTAAAGATTTTTGAAGTGCAGCTACTCCCCACGTGCATTTGATACACATAAAAGTCAT
ACTGTGTGTGCACAAAGAGTACATGGATTTTCCAGCATATTGCTTTAAAAAATTATATAAACTGTTAAAATATTAACACCTCAGGCTACC
TGCTGTATTCTGTCCCATTGACCCCTGGAATTGGATTTACTGCAAGTGATTGATAATTCAATTATGTGGCTTTTCCCCTTTAATCTTGCC
ATTTAAATTACAGTAGAAAGACAAAATCAAGTAAAATAAAGTGTTAGATAATAGAAAGAGTGTTAAGACCAGCCCACTTTTCTCATGTTT
ATGTTCTTTCATTTGGACCAAGAATCTCCGCATGGAGGTTGATTTGCCACTGGGGACTTTGGCTAAGACTATTAGGTTTGCTTTCAACTA
GATGTTCCTGAGACAAGCAGAGGGACACTGCAATTCCCCTTCCATGCCTGCTGTTCTCCCCCATGTAAGTCTTCTTTGAAATTAACGGAT
GTGTCTCCTTTGGAACAGCCCCATAACAAAAGAGAACTACTGATCTGAGCATAGGAAAGTAGAGGCTCTACCACTTTTCAGTTGAAAAAG
CAAGACTTTCTCTGTGTTTCTGAAACAAGGCATAATGTTGTCACAGAATCAGAGATCCAGTCTCACTTTTCCACAAATCTCCAAATCTCC
AGTCTTATCTTGTGTGCTCTAATGGTTTGGTTCAATCCCTTTCCAACTCTTGTTTTCAAAGCATGGGGCCTGAGTGTTCTCCACTCCTCC
TAAGAAAGGAGCTTGGGTGGAAGGGACCATGCTGACCTCCTCCATCAGAGGGCTCTTCCAGTAGTATTCTCGGATGCAACCTCCATTTCT
CAGTTACCATTATTTCCTGTATCAGCTTTGTCCTTCCTGGAGGGATGCACAGTGATCCGGCCCACCACTGTTGTTGTCTTGTGCTTCTGC
TCTTTCCTATGGTTTCAGGTTATTTTCTGGGTTTCCCCTATTCTTCTTTTATTTCTTTTTTTTTTTATATTTGCTTTCCTTTCTACTGCT
TTTAGATTTGCAGGAGATGCAAGTTTCAGCTCAATGTTTGGCTTCTCTCAATATGGAAATTTCAGAAGGACAGAGGAGAGGAGGGAGGAA
GAAGAAAGTATACTCCTCCAGAATTTCAGTGATCTGTTGTGGCAGTCCAGTGGAAGGAAGGTCTTTTGAGGTCACTTAGAAGCATCTTTT
TGGGACATCCTTTTGGGATCTCTGTAGGCTAGGCATCTCATATCTTGAGACTCACCCCCAGCCTCCAAGCCTCTCTCCATTTCTCTAACC
TATGCATTTTAGAGCGAGAGGACCGCCTCACTAGTGTCACCATCCTGCCTTTTCTAAAACATGCAGGCTCACACATTCTACTCCTGCTTA
ATGTCTGTGTTAAACGTTTTCTAACCATTTTTGTTTTATTTTTCTGAAAAAGTTAACCCCTCCCAACTCCTCACACATTGGCTCTTCCTC
TTGAGCCACAAAGTTTTGATTCTTGCGATGTATGTGCCTTATTTTATGTTAATCTTGTCAATGAGAGGGACCAGTTGGTGTTGCCCAATC
AGCACTCCAAGGCTGTGTGTGCACCAGCCAGAGAGCGCACGGTGGTAGCAGAGTCGAGGCTGTCTTGTATCCTGGTTTCATGTGTTGTTT
TGAACTGATAGGAGGATGTTCTCTTCTGACAAGTTACCCTTGTGTATCCTGCAGACATGTAAAATAAAATACAAGTTCATTTTTTTCACC
TTTTTTAGATTTTTTTAAAAAATAAAATGTGTAATCCTTTTTTTAAAAGAAACACATGTAAATACATTTAAGTATTGTAGGCATAGCGTT
CAGATGTGACTGGCCCAGGCGTTCCTCGGACAAGCCTGCATTCCCCGTGATCACGCCCACCTCAAGCCCAGGGGCTGCAGCCCAGCCACA
GATGAACTCTACCTTTGCTTTCAGAACCACTTAGTCCTTTTGTAACAAAGAAAAAAAAATGTTTCTTACAATGTCAATAAAAAATTCTTT

>80496_80496_4_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000435235_GLI3_chr7_42116456_ENST00000395925_length(amino acids)=1574AA_BP=116
MRGRGTEEGAGVEREPVEESACCSVRKQGSYAGRLRCGIGVGAFGESAGCAPLGLVAEGGRGCRSVRDPLLLRRGASTAAPWQQKNLEGY
VGFANLPNQVYRKSVKRGFEFTLMVVDPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHRNPTAAS
ESPFSPPHPYINPYMDYIRSLHSSPSLSMISATRGLSPTDAPHAGVSPAEYYHQMALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDS
TRFSSPRLSARPSRKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMHQQILSR
QQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPE
GTTLVKEEGDKDESKQEPEVIYETNCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH
KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEA
HVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSNS
GLELPLTDGGSIGDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNN
TCSLGGPMTLLPGRSDLSGVDVTMLNMLNRRDSSASTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPISTDASRRS
SEASQSDGLPSLLSLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRLALLGDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHD
APGHGVRRASDPVRTGSEGLALPRVPRFSSLSSCNPPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTMDADANL
NDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGLPDSHAGQQFHALEQPCPEGSKTDLPIQWNEVSSGSADLSSSK
LKCGPRPAVPQTRAFGFCNGMVVHPQNPLRSGPAGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNRQPVAPG
ALDGACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNESAGSMVNGMQNQDPVGQGYLAHQLLGDSMQHPGAGRPGQQMLGQISATSHINI
YQGPESCLPGAHGMGSQPSSLAVVRGYQPCASFGGSRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPLCSNLQNYSGQFYDQ
TVGFSQQDTKAGSFSISDASCLLQGTSAKNSELLSPGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSS

--------------------------------------------------------------
>80496_80496_5_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000469679_GLI3_chr7_42116456_ENST00000395925_length(transcript)=8115nt_BP=359nt
AGCCTCGTCTGAGGGGGCGGGGGACGGAGGAGGGAGCGGGAGTCGAGCGAGAGCCTGTGGAGGAGTCCGCCTGCTGTAGCGTGCGTAAGC
AAGGCAGCTACGCCGGGCGGCTACGCTGCGGAATCGGCGTAGGCGCCTTTGGAGAATCGGCGGGCTGCGCTCCGCTGGGGCTGGTCGCGG
AGGGGGGGAGGGGATGTCGGTCAGTGCGAGATCCGCTGCTGCTGAGGAGAGGAGCGTCAACAGCAGCACCATGGGGCAACAGAAGAACCT
TGAAGGCTATGTGGGATTTGCCAATCTCCCAAATCAAGTATACAGAAAATCGGTGAAGAGAGGTTTTGAATTCACGCTTATGGTAGTGGA
CCCTCCTCATCTTTTCCCTGCCTTCCATCCTCCTGTACCAATTGATGCCAGACATCATGAGGGCCGTTACCATTACGATCCATCTCCGAT
TCCTCCATTGCATATGACTTCCGCCTTATCTAGTAGCCCTACGTATCCGGACCTGCCCTTCATTAGGATCTCCCCACACCGGAACCCCAC
TGCTGCTTCCGAGTCTCCCTTCAGCCCTCCACATCCCTACATTAATCCCTACATGGACTATATCCGCTCCTTGCACAGCAGCCCATCGCT
CTCCATGATCTCAGCAACCCGTGGGCTGAGCCCTACAGATGCGCCCCATGCAGGAGTCAGCCCAGCAGAATACTATCATCAGATGGCCCT
GCTAACTGGCCAGCGCAGCCCCTATGCAGACATTATTCCCTCAGCTGCCACCGCCGGCACGGGGGCCATCCACATGGAATATCTTCATGC
TATGGATAGCACCAGATTCTCCAGCCCCAGGCTGTCAGCCAGGCCGAGCCGAAAACGTACACTGTCCATATCACCACTCTCCGATCATAG
CTTTGACCTTCAGACCATGATAAGGACGTCTCCCAACTCCTTGGTCACGATTCTCAATAATTCCCGTAGCAGCTCTTCAGCAAGTGGCTC
CTATGGTCACTTATCTGCAAGTGCAATCAGCCCTGCCTTGAGCTTCACCTACTCTTCCGCGCCCGTCTCTCTCCACATGCATCAGCAGAT
CCTAAGCCGACAACAGAGCTTAGGTTCAGCCTTTGGACACAGCCCTCCACTCATCCACCCTGCCCCAACTTTTCCAACACAGAGGCCTAT
TCCAGGGATCCCTACGGTTCTGAACCCCGTCCAGGTCAGCTCCGGCCCTTCTGAGTCCTCACAGAACAAGCCCACGAGTGAGTCTGCAGT
GAGCAGCACTGGTGACCCGATGCACAACAAGAGGTCCAAGATCAAACCCGATGAAGACCTCCCCAGCCCAGGGGCTCGGGGGCAGCAGGA
ACAGCCCGAAGGAACAACCCTTGTCAAGGAGGAAGGGGACAAAGATGAAAGCAAACAGGAGCCTGAAGTCATCTATGAGACAAACTGCCA
CTGGGAAGGCTGCGCGAGGGAGTTCGACACCCAAGAGCAGCTTGTGCACCATATAAATAACGACCATATTCATGGAGAGAAGAAGGAGTT
CGTGTGCAGGTGGCTGGACTGCTCAAGAGAGCAGAAACCCTTCAAAGCCCAGTATATGTTGGTAGTGCATATGAGAAGACACACGGGCGA
GAAGCCTCACAAATGCACTTTTGAAGGTTGCACAAAGGCCTACTCGAGACTAGAAAACTTGAAAACACACTTGAGATCTCACACTGGAGA
GAAACCATACGTCTGTGAGCACGAAGGTTGCAACAAGGCTTTCTCAAATGCCTCTGATCGCGCCAAACACCAAAACAGAACGCATTCCAA
TGAGAAACCATATGTGTGCAAAATCCCAGGCTGCACTAAGCGTTACACAGACCCAAGCTCCCTCCGGAAACATGTGAAGACAGTGCATGG
CCCAGAGGCTCATGTCACCAAGAAGCAGCGAGGGGACATCCATCCTCGGCCGCCACCCCCGAGAGATTCCGGCAGCCATTCACAGTCCAG
GTCGCCTGGCCGACCGACTCAGGGAGCCCTTGGTGAGCAGCAGGACCTCAGCAACACTACCTCAAAGCGGGAAGAATGCCTCCAGGTGAA
AACCGTCAAGGCAGAGAAGCCAATGACATCTCAGCCAAGCCCTGGTGGTCAGTCTTCATGCAGCAGCCAACAGTCCCCCATCAGCAACTA
TTCCAACAGTGGGCTCGAGCTTCCTCTGACCGATGGAGGTAGTATAGGAGACCTCAGTGCCATCGATGAAACCCCAATCATGGACTCAAC
CATTTCCACTGCAACCACAGCCCTTGCTTTGCAAGCCAGGAGAAACCCGGCAGGGACCAAATGGATGGAGCACGTAAAACTAGAAAGGCT
AAAACAAGTGAATGGAATGTTTCCGCGACTGAACCCCATTCTACCCCCTAAAGCCCCTGCGGTCTCTCCTCTCATAGGAAATGGCACACA
GTCCAACAACACCTGCAGCTTGGGTGGGCCCATGACGCTTCTCCCGGGCAGAAGCGACCTCTCTGGGGTGGACGTCACTATGCTGAACAT
GCTCAACAGAAGGGACAGCAGCGCCAGCACCATCAGCTCGGCCTACCTGAGCAGCCGCCGCTCCTCAGGGATCTCGCCCTGCTTCTCCAG
CCGCCGCTCCAGCGAGGCGTCACAGGCCGAGGGCCGGCCGCAGAACGTGAGCGTGGCCGACTCCTACGACCCCATCTCCACCGACGCCTC
GCGCCGCTCCAGCGAAGCCAGCCAGAGCGACGGCCTGCCCAGCCTGCTCAGCCTCACGCCCGCCCAGCAGTACCGCCTCAAGGCCAAGTA
CGCGGCTGCCACAGGAGGGCCGCCGCCGACGCCCCTGCCCAACATGGAGAGGATGAGCCTGAAGACGCGCCTGGCGCTGCTCGGGGATGC
CCTCGAGCCTGGCGTGGCCCTGCCTCCAGTTCATGCCCCGAGGAGGTGCAGCGACGGGGGAGCCCACGGCTACGGGCGGCGCCACCTGCA
GCCGCACGATGCGCCGGGCCACGGCGTGAGGAGGGCCAGCGACCCGGTGCGGACAGGCTCCGAGGGCCTGGCCCTGCCTCGTGTGCCGCG
CTTCAGCAGCCTCAGCAGCTGCAACCCCCCGGCGATGGCCACGTCCGCGGAGAAGCGCAGTCTCGTGCTTCAGAATTACACGCGGCCCGA
GGGCGGCCAGTCCCGAAACTTCCACTCGTCCCCCTGTCCTCCCAGCATCACCGAGAACGTCACCCTGGAGTCCCTGACCATGGACGCTGA
TGCCAACCTGAACGATGAGGATTTCCTGCCGGACGACGTGGTGCAGTATTTAAATTCCCAGAACCAAGCAGGGTACGAGCAGCACTTCCC
CAGCGCCCTCCCGGACGACAGCAAAGTGCCCCACGGGCCCGGTGACTTTGACGCGCCCGGGCTGCCAGACAGCCACGCTGGCCAGCAGTT
CCATGCCCTCGAGCAGCCCTGCCCCGAGGGCAGCAAAACCGACCTGCCCATTCAGTGGAACGAAGTCAGCTCCGGAAGCGCCGACCTGTC
CTCCTCCAAGCTCAAGTGTGGGCCGCGGCCCGCTGTGCCGCAGACTCGCGCCTTTGGGTTCTGCAACGGCATGGTCGTCCACCCGCAGAA
CCCCTTGAGGAGCGGGCCTGCTGGGGGCTATCAGACCCTCGGGGAGAACAGCAACCCCTACGGTGGCCCAGAGCACTTGATGCTCCACAA
CAGCCCCGGAAGTGGCACCAGTGGAAACGCCTTCCATGAACAGCCCTGTAAGGCCCCGCAGTATGGGAACTGTCTCAACAGGCAGCCAGT
GGCCCCTGGTGCACTCGACGGTGCCTGTGGTGCCGGGATTCAAGCCTCAAAGCTGAAGAGCACCCCCATGCAAGGGAGCGGGGGCCAGCT
GAATTTCGGCCTGCCGGTAGCGCCAAATGAGTCAGCTGGCAGCATGGTGAATGGCATGCAGAACCAGGACCCAGTGGGACAGGGGTACCT
GGCTCACCAGCTCCTCGGCGACAGCATGCAGCACCCGGGGGCAGGCCGCCCCGGTCAGCAGATGCTTGGGCAGATTAGTGCTACCTCACA
CATCAACATCTACCAAGGGCCAGAGAGCTGCCTGCCAGGGGCTCACGGCATGGGCAGCCAGCCGTCAAGCTTGGCAGTTGTCAGGGGCTA
CCAGCCATGTGCCAGCTTTGGGGGCAGCAGGCGCCAGGCTATGCCGAGGGACAGCCTTGCTCTGCAGTCAGGACAGCTCAGTGACACAAG
TCAGACCTGCAGGGTGAATGGTATCAAGATGGAGATGAAAGGGCAGCCCCATCCGCTGTGCTCTAATCTGCAGAATTACTCTGGTCAGTT
CTATGACCAAACCGTGGGCTTCAGTCAGCAAGACACGAAAGCTGGTTCATTCTCTATTTCAGACGCCAGCTGCCTGCTACAGGGGACCAG
CGCCAAAAACTCTGAGTTACTTTCCCCAGGTGCTAATCAGGTGACAAGCACAGTGGACAGCCTCGACAGCCATGACCTGGAAGGGGTACA
GATTGACTTCGATGCCATCATAGACGATGGGGACCACTCCAGCCTGATGTCGGGGGCCCTGAGCCCAAGTATCATTCAGAACCTTTCCCA
TAGCTCCTCCCGCCTCACCACGCCTCGGGCGTCCCTCCCATTCCCAGCGCTGTCCATGAGCACCACCAACATGGCTATCGGGGACATGAG
TTCTTTGCTGACCTCCCTAGCGGAAGAAAGCAAATTCCTTGCAGTTATGCAATAGGCTTTAGGAAAAAAAGACTGCAACCAACGGAAATC
AATAGGAGTTGAAGAGATTAAACTGACTTTGTTTTGGCTGTTTTTTTAGTTCTGTATGTATTTTAGCAATCTCATCTCACCTAACTGAGA
TGTGTTTCAATTATATTCCTTTTATGGAAAAGGACTCTGAAAAACCCTAAAGTATTCTAGGGAGAAACTGTCTTCCATTTCAGTTTTGAA
TCAGTATTGTTACACTCAAACCACCCTCTTTTTAAAAAAAAAAAAAAAAACTGTAAGCCCCGCCCCCTTTTTAGTAAACCGATGTAAATT
TGTGATGTGCATATTCTTCTTTCTTTTAGAAGAGCAGTCAAATTAAAGGATTTGACATGTTTTGCTGTTGCTCAAAGGAAATAGGAGTTG
GTGTGCTTGTGACCAAGGGGTTACACTTCCAGCTTTTAAAATTCTCCTTTACATGTGCTCAGTGTTTTGTTTTGTGTTTTGGTTTCTGTT
TTTTATTTTAATTCCCACATTGGGCACAAGAATCAGAATATGGATAGCTAGTTTAAGAAACTTTTGTGGGTGCACTGTAGCATAGATGAC
AGAATATTGATGTTCCCCCCATCTCCAATTCAGTTCAGGGCATTCCACAGTTAAACAGAAATGGGAACGTGGGGCTCTTATAAATGAAAT
GGGCGCTCACAGTTTTGGTTTTCAGCTCTTCATGTCTGTAAGTGTGCTTTGGGGGAGGCTATGTCTGTATGGTCGATTCTCAGTTATCAC
ATTTGCCTCTCCTCCCACTACCTTCATGAACATTCAGTGCTGTTTCGCACTGCAGTTAGAGAGAAGGGACGGACAGTTGGTGACACTCAG
CCACATTGCTACTTTTATCTGTTCTGGTAAGAAGTTAGATAGATGGTAGATTGAAGCAATTGGGTAGAATTAGTTGGGGGAATATTTATG
AGTTGCTGTGTTTGTTGATTAGTTCCATCTCTTTCCCATTTTAACTGAGAATTGATTATATATAGCTCTAAGTATATAGGTATTTAAACA
ACCCCACAAGCGGCTGTATCAGTAACATTTATTAATTCCACTATAGTGAGGGAGGATTTCCATTCTAAATACCTTATTTTGAGGGATTTA
TAAAACTTAGTTGTAAAAGAGAAAGCCCACATAGTGGGAATAAATTGCTTCAGCCATTTTTAGTATTTGAGAGCACTAGGGAAGATGTTT
AGTAGCTGTGTGGATGCCTTTTTTCACACCCTGTCTATTGAATGCTGCATCCATTCACGAAGTTAAATGTTACATGCAGTTAGTCCTTAA
TGTGGACTGGATCTGTACTTTTGTTTTGGATTAAAACATTTAAAGATTTTTGAAGTGCAGCTACTCCCCACGTGCATTTGATACACATAA
AAGTCATACTGTGTGTGCACAAAGAGTACATGGATTTTCCAGCATATTGCTTTAAAAAATTATATAAACTGTTAAAATATTAACACCTCA
GGCTACCTGCTGTATTCTGTCCCATTGACCCCTGGAATTGGATTTACTGCAAGTGATTGATAATTCAATTATGTGGCTTTTCCCCTTTAA
TCTTGCCATTTAAATTACAGTAGAAAGACAAAATCAAGTAAAATAAAGTGTTAGATAATAGAAAGAGTGTTAAGACCAGCCCACTTTTCT
CATGTTTATGTTCTTTCATTTGGACCAAGAATCTCCGCATGGAGGTTGATTTGCCACTGGGGACTTTGGCTAAGACTATTAGGTTTGCTT
TCAACTAGATGTTCCTGAGACAAGCAGAGGGACACTGCAATTCCCCTTCCATGCCTGCTGTTCTCCCCCATGTAAGTCTTCTTTGAAATT
AACGGATGTGTCTCCTTTGGAACAGCCCCATAACAAAAGAGAACTACTGATCTGAGCATAGGAAAGTAGAGGCTCTACCACTTTTCAGTT
GAAAAAGCAAGACTTTCTCTGTGTTTCTGAAACAAGGCATAATGTTGTCACAGAATCAGAGATCCAGTCTCACTTTTCCACAAATCTCCA
AATCTCCAGTCTTATCTTGTGTGCTCTAATGGTTTGGTTCAATCCCTTTCCAACTCTTGTTTTCAAAGCATGGGGCCTGAGTGTTCTCCA
CTCCTCCTAAGAAAGGAGCTTGGGTGGAAGGGACCATGCTGACCTCCTCCATCAGAGGGCTCTTCCAGTAGTATTCTCGGATGCAACCTC
CATTTCTCAGTTACCATTATTTCCTGTATCAGCTTTGTCCTTCCTGGAGGGATGCACAGTGATCCGGCCCACCACTGTTGTTGTCTTGTG
CTTCTGCTCTTTCCTATGGTTTCAGGTTATTTTCTGGGTTTCCCCTATTCTTCTTTTATTTCTTTTTTTTTTTATATTTGCTTTCCTTTC
TACTGCTTTTAGATTTGCAGGAGATGCAAGTTTCAGCTCAATGTTTGGCTTCTCTCAATATGGAAATTTCAGAAGGACAGAGGAGAGGAG
GGAGGAAGAAGAAAGTATACTCCTCCAGAATTTCAGTGATCTGTTGTGGCAGTCCAGTGGAAGGAAGGTCTTTTGAGGTCACTTAGAAGC
ATCTTTTTGGGACATCCTTTTGGGATCTCTGTAGGCTAGGCATCTCATATCTTGAGACTCACCCCCAGCCTCCAAGCCTCTCTCCATTTC
TCTAACCTATGCATTTTAGAGCGAGAGGACCGCCTCACTAGTGTCACCATCCTGCCTTTTCTAAAACATGCAGGCTCACACATTCTACTC
CTGCTTAATGTCTGTGTTAAACGTTTTCTAACCATTTTTGTTTTATTTTTCTGAAAAAGTTAACCCCTCCCAACTCCTCACACATTGGCT
CTTCCTCTTGAGCCACAAAGTTTTGATTCTTGCGATGTATGTGCCTTATTTTATGTTAATCTTGTCAATGAGAGGGACCAGTTGGTGTTG
CCCAATCAGCACTCCAAGGCTGTGTGTGCACCAGCCAGAGAGCGCACGGTGGTAGCAGAGTCGAGGCTGTCTTGTATCCTGGTTTCATGT
GTTGTTTTGAACTGATAGGAGGATGTTCTCTTCTGACAAGTTACCCTTGTGTATCCTGCAGACATGTAAAATAAAATACAAGTTCATTTT
TTTCACCTTTTTTAGATTTTTTTAAAAAATAAAATGTGTAATCCTTTTTTTAAAAGAAACACATGTAAATACATTTAAGTATTGTAGGCA
TAGCGTTCAGATGTGACTGGCCCAGGCGTTCCTCGGACAAGCCTGCATTCCCCGTGATCACGCCCACCTCAAGCCCAGGGGCTGCAGCCC
AGCCACAGATGAACTCTACCTTTGCTTTCAGAACCACTTAGTCCTTTTGTAACAAAGAAAAAAAAATGTTTCTTACAATGTCAATAAAAA

>80496_80496_5_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000469679_GLI3_chr7_42116456_ENST00000395925_length(amino acids)=1539AA_BP=81
MRNRRRRLWRIGGLRSAGAGRGGGEGMSVSARSAAAEERSVNSSTMGQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVDPPHLFPAF
HPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISATRG
LSPTDAPHAGVSPAEYYHQMALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLSDHSFDLQTMIR
TSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLN
PVQVSSGPSESSQNKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYETNCHWEGCAREF
DTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHE
GCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPTQG
ALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATTAL
ALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTMLNMLNRRDSSA
STISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPISTDASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAATGGPP
PTPLPNMERMSLKTRLALLGDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGVRRASDPVRTGSEGLALPRVPRFSSLSSCN
PPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTMDADANLNDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDDSK
VPHGPGDFDAPGLPDSHAGQQFHALEQPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVHPQNPLRSGPAG
GYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNRQPVAPGALDGACGAGIQASKLKSTPMQGSGGQLNFGLPVAP
NESAGSMVNGMQNQDPVGQGYLAHQLLGDSMQHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAHGMGSQPSSLAVVRGYQPCASFGG
SRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPLCSNLQNYSGQFYDQTVGFSQQDTKAGSFSISDASCLLQGTSAKNSELLS
PGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIGDMSSLLTSLAE

--------------------------------------------------------------
>80496_80496_6_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000494488_GLI3_chr7_42116456_ENST00000395925_length(transcript)=7883nt_BP=127nt
GTTACTCACGAAACTATTGTTGAGCAACAGAAGAACCTTGAAGGCTATGTGGGATTTGCCAATCTCCCAAATCAAGTATACAGAAAATCG
GTGAAGAGAGGTTTTGAATTCACGCTTATGGTAGTGGACCCTCCTCATCTTTTCCCTGCCTTCCATCCTCCTGTACCAATTGATGCCAGA
CATCATGAGGGCCGTTACCATTACGATCCATCTCCGATTCCTCCATTGCATATGACTTCCGCCTTATCTAGTAGCCCTACGTATCCGGAC
CTGCCCTTCATTAGGATCTCCCCACACCGGAACCCCACTGCTGCTTCCGAGTCTCCCTTCAGCCCTCCACATCCCTACATTAATCCCTAC
ATGGACTATATCCGCTCCTTGCACAGCAGCCCATCGCTCTCCATGATCTCAGCAACCCGTGGGCTGAGCCCTACAGATGCGCCCCATGCA
GGAGTCAGCCCAGCAGAATACTATCATCAGATGGCCCTGCTAACTGGCCAGCGCAGCCCCTATGCAGACATTATTCCCTCAGCTGCCACC
GCCGGCACGGGGGCCATCCACATGGAATATCTTCATGCTATGGATAGCACCAGATTCTCCAGCCCCAGGCTGTCAGCCAGGCCGAGCCGA
AAACGTACACTGTCCATATCACCACTCTCCGATCATAGCTTTGACCTTCAGACCATGATAAGGACGTCTCCCAACTCCTTGGTCACGATT
CTCAATAATTCCCGTAGCAGCTCTTCAGCAAGTGGCTCCTATGGTCACTTATCTGCAAGTGCAATCAGCCCTGCCTTGAGCTTCACCTAC
TCTTCCGCGCCCGTCTCTCTCCACATGCATCAGCAGATCCTAAGCCGACAACAGAGCTTAGGTTCAGCCTTTGGACACAGCCCTCCACTC
ATCCACCCTGCCCCAACTTTTCCAACACAGAGGCCTATTCCAGGGATCCCTACGGTTCTGAACCCCGTCCAGGTCAGCTCCGGCCCTTCT
GAGTCCTCACAGAACAAGCCCACGAGTGAGTCTGCAGTGAGCAGCACTGGTGACCCGATGCACAACAAGAGGTCCAAGATCAAACCCGAT
GAAGACCTCCCCAGCCCAGGGGCTCGGGGGCAGCAGGAACAGCCCGAAGGAACAACCCTTGTCAAGGAGGAAGGGGACAAAGATGAAAGC
AAACAGGAGCCTGAAGTCATCTATGAGACAAACTGCCACTGGGAAGGCTGCGCGAGGGAGTTCGACACCCAAGAGCAGCTTGTGCACCAT
ATAAATAACGACCATATTCATGGAGAGAAGAAGGAGTTCGTGTGCAGGTGGCTGGACTGCTCAAGAGAGCAGAAACCCTTCAAAGCCCAG
TATATGTTGGTAGTGCATATGAGAAGACACACGGGCGAGAAGCCTCACAAATGCACTTTTGAAGGTTGCACAAAGGCCTACTCGAGACTA
GAAAACTTGAAAACACACTTGAGATCTCACACTGGAGAGAAACCATACGTCTGTGAGCACGAAGGTTGCAACAAGGCTTTCTCAAATGCC
TCTGATCGCGCCAAACACCAAAACAGAACGCATTCCAATGAGAAACCATATGTGTGCAAAATCCCAGGCTGCACTAAGCGTTACACAGAC
CCAAGCTCCCTCCGGAAACATGTGAAGACAGTGCATGGCCCAGAGGCTCATGTCACCAAGAAGCAGCGAGGGGACATCCATCCTCGGCCG
CCACCCCCGAGAGATTCCGGCAGCCATTCACAGTCCAGGTCGCCTGGCCGACCGACTCAGGGAGCCCTTGGTGAGCAGCAGGACCTCAGC
AACACTACCTCAAAGCGGGAAGAATGCCTCCAGGTGAAAACCGTCAAGGCAGAGAAGCCAATGACATCTCAGCCAAGCCCTGGTGGTCAG
TCTTCATGCAGCAGCCAACAGTCCCCCATCAGCAACTATTCCAACAGTGGGCTCGAGCTTCCTCTGACCGATGGAGGTAGTATAGGAGAC
CTCAGTGCCATCGATGAAACCCCAATCATGGACTCAACCATTTCCACTGCAACCACAGCCCTTGCTTTGCAAGCCAGGAGAAACCCGGCA
GGGACCAAATGGATGGAGCACGTAAAACTAGAAAGGCTAAAACAAGTGAATGGAATGTTTCCGCGACTGAACCCCATTCTACCCCCTAAA
GCCCCTGCGGTCTCTCCTCTCATAGGAAATGGCACACAGTCCAACAACACCTGCAGCTTGGGTGGGCCCATGACGCTTCTCCCGGGCAGA
AGCGACCTCTCTGGGGTGGACGTCACTATGCTGAACATGCTCAACAGAAGGGACAGCAGCGCCAGCACCATCAGCTCGGCCTACCTGAGC
AGCCGCCGCTCCTCAGGGATCTCGCCCTGCTTCTCCAGCCGCCGCTCCAGCGAGGCGTCACAGGCCGAGGGCCGGCCGCAGAACGTGAGC
GTGGCCGACTCCTACGACCCCATCTCCACCGACGCCTCGCGCCGCTCCAGCGAAGCCAGCCAGAGCGACGGCCTGCCCAGCCTGCTCAGC
CTCACGCCCGCCCAGCAGTACCGCCTCAAGGCCAAGTACGCGGCTGCCACAGGAGGGCCGCCGCCGACGCCCCTGCCCAACATGGAGAGG
ATGAGCCTGAAGACGCGCCTGGCGCTGCTCGGGGATGCCCTCGAGCCTGGCGTGGCCCTGCCTCCAGTTCATGCCCCGAGGAGGTGCAGC
GACGGGGGAGCCCACGGCTACGGGCGGCGCCACCTGCAGCCGCACGATGCGCCGGGCCACGGCGTGAGGAGGGCCAGCGACCCGGTGCGG
ACAGGCTCCGAGGGCCTGGCCCTGCCTCGTGTGCCGCGCTTCAGCAGCCTCAGCAGCTGCAACCCCCCGGCGATGGCCACGTCCGCGGAG
AAGCGCAGTCTCGTGCTTCAGAATTACACGCGGCCCGAGGGCGGCCAGTCCCGAAACTTCCACTCGTCCCCCTGTCCTCCCAGCATCACC
GAGAACGTCACCCTGGAGTCCCTGACCATGGACGCTGATGCCAACCTGAACGATGAGGATTTCCTGCCGGACGACGTGGTGCAGTATTTA
AATTCCCAGAACCAAGCAGGGTACGAGCAGCACTTCCCCAGCGCCCTCCCGGACGACAGCAAAGTGCCCCACGGGCCCGGTGACTTTGAC
GCGCCCGGGCTGCCAGACAGCCACGCTGGCCAGCAGTTCCATGCCCTCGAGCAGCCCTGCCCCGAGGGCAGCAAAACCGACCTGCCCATT
CAGTGGAACGAAGTCAGCTCCGGAAGCGCCGACCTGTCCTCCTCCAAGCTCAAGTGTGGGCCGCGGCCCGCTGTGCCGCAGACTCGCGCC
TTTGGGTTCTGCAACGGCATGGTCGTCCACCCGCAGAACCCCTTGAGGAGCGGGCCTGCTGGGGGCTATCAGACCCTCGGGGAGAACAGC
AACCCCTACGGTGGCCCAGAGCACTTGATGCTCCACAACAGCCCCGGAAGTGGCACCAGTGGAAACGCCTTCCATGAACAGCCCTGTAAG
GCCCCGCAGTATGGGAACTGTCTCAACAGGCAGCCAGTGGCCCCTGGTGCACTCGACGGTGCCTGTGGTGCCGGGATTCAAGCCTCAAAG
CTGAAGAGCACCCCCATGCAAGGGAGCGGGGGCCAGCTGAATTTCGGCCTGCCGGTAGCGCCAAATGAGTCAGCTGGCAGCATGGTGAAT
GGCATGCAGAACCAGGACCCAGTGGGACAGGGGTACCTGGCTCACCAGCTCCTCGGCGACAGCATGCAGCACCCGGGGGCAGGCCGCCCC
GGTCAGCAGATGCTTGGGCAGATTAGTGCTACCTCACACATCAACATCTACCAAGGGCCAGAGAGCTGCCTGCCAGGGGCTCACGGCATG
GGCAGCCAGCCGTCAAGCTTGGCAGTTGTCAGGGGCTACCAGCCATGTGCCAGCTTTGGGGGCAGCAGGCGCCAGGCTATGCCGAGGGAC
AGCCTTGCTCTGCAGTCAGGACAGCTCAGTGACACAAGTCAGACCTGCAGGGTGAATGGTATCAAGATGGAGATGAAAGGGCAGCCCCAT
CCGCTGTGCTCTAATCTGCAGAATTACTCTGGTCAGTTCTATGACCAAACCGTGGGCTTCAGTCAGCAAGACACGAAAGCTGGTTCATTC
TCTATTTCAGACGCCAGCTGCCTGCTACAGGGGACCAGCGCCAAAAACTCTGAGTTACTTTCCCCAGGTGCTAATCAGGTGACAAGCACA
GTGGACAGCCTCGACAGCCATGACCTGGAAGGGGTACAGATTGACTTCGATGCCATCATAGACGATGGGGACCACTCCAGCCTGATGTCG
GGGGCCCTGAGCCCAAGTATCATTCAGAACCTTTCCCATAGCTCCTCCCGCCTCACCACGCCTCGGGCGTCCCTCCCATTCCCAGCGCTG
TCCATGAGCACCACCAACATGGCTATCGGGGACATGAGTTCTTTGCTGACCTCCCTAGCGGAAGAAAGCAAATTCCTTGCAGTTATGCAA
TAGGCTTTAGGAAAAAAAGACTGCAACCAACGGAAATCAATAGGAGTTGAAGAGATTAAACTGACTTTGTTTTGGCTGTTTTTTTAGTTC
TGTATGTATTTTAGCAATCTCATCTCACCTAACTGAGATGTGTTTCAATTATATTCCTTTTATGGAAAAGGACTCTGAAAAACCCTAAAG
TATTCTAGGGAGAAACTGTCTTCCATTTCAGTTTTGAATCAGTATTGTTACACTCAAACCACCCTCTTTTTAAAAAAAAAAAAAAAAACT
GTAAGCCCCGCCCCCTTTTTAGTAAACCGATGTAAATTTGTGATGTGCATATTCTTCTTTCTTTTAGAAGAGCAGTCAAATTAAAGGATT
TGACATGTTTTGCTGTTGCTCAAAGGAAATAGGAGTTGGTGTGCTTGTGACCAAGGGGTTACACTTCCAGCTTTTAAAATTCTCCTTTAC
ATGTGCTCAGTGTTTTGTTTTGTGTTTTGGTTTCTGTTTTTTATTTTAATTCCCACATTGGGCACAAGAATCAGAATATGGATAGCTAGT
TTAAGAAACTTTTGTGGGTGCACTGTAGCATAGATGACAGAATATTGATGTTCCCCCCATCTCCAATTCAGTTCAGGGCATTCCACAGTT
AAACAGAAATGGGAACGTGGGGCTCTTATAAATGAAATGGGCGCTCACAGTTTTGGTTTTCAGCTCTTCATGTCTGTAAGTGTGCTTTGG
GGGAGGCTATGTCTGTATGGTCGATTCTCAGTTATCACATTTGCCTCTCCTCCCACTACCTTCATGAACATTCAGTGCTGTTTCGCACTG
CAGTTAGAGAGAAGGGACGGACAGTTGGTGACACTCAGCCACATTGCTACTTTTATCTGTTCTGGTAAGAAGTTAGATAGATGGTAGATT
GAAGCAATTGGGTAGAATTAGTTGGGGGAATATTTATGAGTTGCTGTGTTTGTTGATTAGTTCCATCTCTTTCCCATTTTAACTGAGAAT
TGATTATATATAGCTCTAAGTATATAGGTATTTAAACAACCCCACAAGCGGCTGTATCAGTAACATTTATTAATTCCACTATAGTGAGGG
AGGATTTCCATTCTAAATACCTTATTTTGAGGGATTTATAAAACTTAGTTGTAAAAGAGAAAGCCCACATAGTGGGAATAAATTGCTTCA
GCCATTTTTAGTATTTGAGAGCACTAGGGAAGATGTTTAGTAGCTGTGTGGATGCCTTTTTTCACACCCTGTCTATTGAATGCTGCATCC
ATTCACGAAGTTAAATGTTACATGCAGTTAGTCCTTAATGTGGACTGGATCTGTACTTTTGTTTTGGATTAAAACATTTAAAGATTTTTG
AAGTGCAGCTACTCCCCACGTGCATTTGATACACATAAAAGTCATACTGTGTGTGCACAAAGAGTACATGGATTTTCCAGCATATTGCTT
TAAAAAATTATATAAACTGTTAAAATATTAACACCTCAGGCTACCTGCTGTATTCTGTCCCATTGACCCCTGGAATTGGATTTACTGCAA
GTGATTGATAATTCAATTATGTGGCTTTTCCCCTTTAATCTTGCCATTTAAATTACAGTAGAAAGACAAAATCAAGTAAAATAAAGTGTT
AGATAATAGAAAGAGTGTTAAGACCAGCCCACTTTTCTCATGTTTATGTTCTTTCATTTGGACCAAGAATCTCCGCATGGAGGTTGATTT
GCCACTGGGGACTTTGGCTAAGACTATTAGGTTTGCTTTCAACTAGATGTTCCTGAGACAAGCAGAGGGACACTGCAATTCCCCTTCCAT
GCCTGCTGTTCTCCCCCATGTAAGTCTTCTTTGAAATTAACGGATGTGTCTCCTTTGGAACAGCCCCATAACAAAAGAGAACTACTGATC
TGAGCATAGGAAAGTAGAGGCTCTACCACTTTTCAGTTGAAAAAGCAAGACTTTCTCTGTGTTTCTGAAACAAGGCATAATGTTGTCACA
GAATCAGAGATCCAGTCTCACTTTTCCACAAATCTCCAAATCTCCAGTCTTATCTTGTGTGCTCTAATGGTTTGGTTCAATCCCTTTCCA
ACTCTTGTTTTCAAAGCATGGGGCCTGAGTGTTCTCCACTCCTCCTAAGAAAGGAGCTTGGGTGGAAGGGACCATGCTGACCTCCTCCAT
CAGAGGGCTCTTCCAGTAGTATTCTCGGATGCAACCTCCATTTCTCAGTTACCATTATTTCCTGTATCAGCTTTGTCCTTCCTGGAGGGA
TGCACAGTGATCCGGCCCACCACTGTTGTTGTCTTGTGCTTCTGCTCTTTCCTATGGTTTCAGGTTATTTTCTGGGTTTCCCCTATTCTT
CTTTTATTTCTTTTTTTTTTTATATTTGCTTTCCTTTCTACTGCTTTTAGATTTGCAGGAGATGCAAGTTTCAGCTCAATGTTTGGCTTC
TCTCAATATGGAAATTTCAGAAGGACAGAGGAGAGGAGGGAGGAAGAAGAAAGTATACTCCTCCAGAATTTCAGTGATCTGTTGTGGCAG
TCCAGTGGAAGGAAGGTCTTTTGAGGTCACTTAGAAGCATCTTTTTGGGACATCCTTTTGGGATCTCTGTAGGCTAGGCATCTCATATCT
TGAGACTCACCCCCAGCCTCCAAGCCTCTCTCCATTTCTCTAACCTATGCATTTTAGAGCGAGAGGACCGCCTCACTAGTGTCACCATCC
TGCCTTTTCTAAAACATGCAGGCTCACACATTCTACTCCTGCTTAATGTCTGTGTTAAACGTTTTCTAACCATTTTTGTTTTATTTTTCT
GAAAAAGTTAACCCCTCCCAACTCCTCACACATTGGCTCTTCCTCTTGAGCCACAAAGTTTTGATTCTTGCGATGTATGTGCCTTATTTT
ATGTTAATCTTGTCAATGAGAGGGACCAGTTGGTGTTGCCCAATCAGCACTCCAAGGCTGTGTGTGCACCAGCCAGAGAGCGCACGGTGG
TAGCAGAGTCGAGGCTGTCTTGTATCCTGGTTTCATGTGTTGTTTTGAACTGATAGGAGGATGTTCTCTTCTGACAAGTTACCCTTGTGT
ATCCTGCAGACATGTAAAATAAAATACAAGTTCATTTTTTTCACCTTTTTTAGATTTTTTTAAAAAATAAAATGTGTAATCCTTTTTTTA
AAAGAAACACATGTAAATACATTTAAGTATTGTAGGCATAGCGTTCAGATGTGACTGGCCCAGGCGTTCCTCGGACAAGCCTGCATTCCC
CGTGATCACGCCCACCTCAAGCCCAGGGGCTGCAGCCCAGCCACAGATGAACTCTACCTTTGCTTTCAGAACCACTTAGTCCTTTTGTAA

>80496_80496_6_SEPT7-GLI3_SEPT7_chr7_35872510_ENST00000494488_GLI3_chr7_42116456_ENST00000395925_length(amino acids)=1461AA_BP=3
MVVDPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMDYIRSLHS
SPSLSMISATRGLSPTDAPHAGVSPAEYYHQMALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPL
SDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPT
QRPIPGIPTVLNPVQVSSGPSESSQNKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYE
TNCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRS
HTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSH
SQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSNSGLELPLTDGGSIGDLSAIDETPI
MDSTISTATTALALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVT
MLNMLNRRDSSASTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPISTDASRRSSEASQSDGLPSLLSLTPAQQYRL
KAKYAAATGGPPPTPLPNMERMSLKTRLALLGDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGVRRASDPVRTGSEGLALP
RVPRFSSLSSCNPPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTMDADANLNDEDFLPDDVVQYLNSQNQAGYE
QHFPSALPDDSKVPHGPGDFDAPGLPDSHAGQQFHALEQPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVV
HPQNPLRSGPAGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNRQPVAPGALDGACGAGIQASKLKSTPMQGS
GGQLNFGLPVAPNESAGSMVNGMQNQDPVGQGYLAHQLLGDSMQHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAHGMGSQPSSLAV
VRGYQPCASFGGSRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPLCSNLQNYSGQFYDQTVGFSQQDTKAGSFSISDASCLL
QGTSAKNSELLSPGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAI

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Fusion Gene PPI Analysis for SEPT7-GLI3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSEPT7chr7:35872510chr7:42116456ENST00000399034+31447_31757.333333333333336439.0SEPTIN12


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SEPT7-GLI3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SEPT7-GLI3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource