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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SEPT9-VAV1 (FusionGDB2 ID:80538)

Fusion Gene Summary for SEPT9-VAV1

check button Fusion gene summary
Fusion gene informationFusion gene name: SEPT9-VAV1
Fusion gene ID: 80538
HgeneTgene
Gene symbol

SEPT9

VAV1

Gene ID

10801

7409

Gene nameseptin 9vav guanine nucleotide exchange factor 1
SynonymsAF17q25|MSF|MSF1|NAPB|PNUTL4|SEPT9|SINT1|SeptD1VAV
Cytomap

17q25.3

19p13.3

Type of geneprotein-codingprotein-coding
Descriptionseptin-9MLL septin-like fusion protein MSF-AOv/Br septinovarian/breast septinseptin D1proto-oncogene vavvav 1 guanine nucleotide exchange factorvav 1 oncogene
Modification date2020032820200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000423034, ENST00000329047, 
ENST00000427177, ENST00000427180, 
ENST00000427674, ENST00000431235, 
ENST00000449803, ENST00000541152, 
ENST00000585930, ENST00000588690, 
ENST00000590294, ENST00000590917, 
ENST00000591088, ENST00000591198, 
ENST00000592420, ENST00000592481, 
ENST00000592951, 		ENST00000304076, 
ENST00000539284, ENST00000596764, 
ENST00000599806, ENST00000602142, 
Fusion gene scores* DoF score31 X 14 X 18=781210 X 11 X 8=880
# samples 4112
** MAII scorelog2(41/7812*10)=-4.25199613438135
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/880*10)=-2.87446911791614
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SEPT9 [Title/Abstract] AND VAV1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSEPT9(75369634)-VAV1(6836443), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SEPT9 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across VAV1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ACCTCGA-OR-A5JA-01ASEPT9chr17

75369634

-VAV1chr19

6836443

+


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Fusion Gene ORF analysis for SEPT9-VAV1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000423034ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
In-frameENST00000423034ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
In-frameENST00000423034ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
In-frameENST00000423034ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
In-frameENST00000423034ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000329047ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000329047ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000329047ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000329047ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000329047ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427177ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427177ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427177ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427177ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427177ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427180ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427180ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427180ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427180ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427180ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427674ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427674ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427674ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427674ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000427674ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000431235ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000431235ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000431235ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000431235ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000431235ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000449803ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000449803ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000449803ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000449803ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000449803ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000541152ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000541152ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000541152ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000541152ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000541152ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000585930ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000585930ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000585930ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000585930ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000585930ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000588690ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000588690ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000588690ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000588690ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000588690ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000590294ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000590294ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000590294ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000590294ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000590294ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000590917ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000590917ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000590917ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000590917ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000590917ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000591088ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000591088ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000591088ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000591088ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000591088ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000591198ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000591198ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000591198ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000591198ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000591198ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592420ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592420ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592420ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592420ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592420ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592481ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592481ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592481ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592481ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592481ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592951ENST00000304076SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592951ENST00000539284SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592951ENST00000596764SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592951ENST00000599806SEPT9chr17

75369634

-VAV1chr19

6836443

+
intron-3CDSENST00000592951ENST00000602142SEPT9chr17

75369634

-VAV1chr19

6836443

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000423034SEPT9chr1775369634-ENST00000304076VAV1chr196836443+13173633081057249
ENST00000423034SEPT9chr1775369634-ENST00000602142VAV1chr196836443+11243633081123272
ENST00000423034SEPT9chr1775369634-ENST00000596764VAV1chr196836443+13773633081123271
ENST00000423034SEPT9chr1775369634-ENST00000539284VAV1chr196836443+13773633081123271
ENST00000423034SEPT9chr1775369634-ENST00000599806VAV1chr196836443+13833633081123271

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000423034ENST00000304076SEPT9chr1775369634-VAV1chr196836443+0.0069093520.9930906
ENST00000423034ENST00000602142SEPT9chr1775369634-VAV1chr196836443+0.0049150750.99508494
ENST00000423034ENST00000596764SEPT9chr1775369634-VAV1chr196836443+0.0044744440.99552554
ENST00000423034ENST00000539284SEPT9chr1775369634-VAV1chr196836443+0.0044744440.99552554
ENST00000423034ENST00000599806SEPT9chr1775369634-VAV1chr196836443+0.0045937420.99540627

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Fusion Genomic Features for SEPT9-VAV1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SEPT9-VAV1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:75369634/chr19:6836443)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneVAV1chr17:75369634chr19:6836443ENST000005967641726592_660560814.0DomainSH3 1
TgeneVAV1chr17:75369634chr19:6836443ENST000005967641726671_765560814.0DomainSH2
TgeneVAV1chr17:75369634chr19:6836443ENST000005967641726782_842560814.0DomainSH3 2
TgeneVAV1chr17:75369634chr19:6836443ENST000006021421827592_660592846.0DomainSH3 1
TgeneVAV1chr17:75369634chr19:6836443ENST000006021421827671_765592846.0DomainSH2
TgeneVAV1chr17:75369634chr19:6836443ENST000006021421827782_842592846.0DomainSH3 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSEPT9chr17:75369634chr19:6836443ENST00000329047-111295_5670569.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000423034-111295_56718580.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427177-112295_5670587.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427180-110295_5670475.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427674-111295_5670423.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000431235-112295_5670423.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000449803-112295_5670423.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000541152-110295_5670336.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000585930-110295_5670363.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000588690-112295_5670512.6666666666666DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000590294-112295_5670354.3333333333333DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000591088-110295_5670336.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000591198-111295_5670568.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000592951-110295_5670336.0DomainSeptin-type G
HgeneSEPT9chr17:75369634chr19:6836443ENST00000329047-111445_4530569.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000423034-111445_45318580.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427177-112445_4530587.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427180-110445_4530475.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427674-111445_4530423.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000431235-112445_4530423.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000449803-112445_4530423.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000541152-110445_4530336.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000585930-110445_4530363.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000588690-112445_4530512.6666666666666Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000590294-112445_4530354.3333333333333Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000591088-110445_4530336.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000591198-111445_4530568.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000592951-110445_4530336.0Nucleotide bindingGTP
HgeneSEPT9chr17:75369634chr19:6836443ENST00000329047-111305_3120569.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000329047-111362_3650569.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000329047-111444_4470569.0RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000423034-111305_31218580.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000423034-111362_36518580.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000423034-111444_44718580.0RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427177-112305_3120587.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427177-112362_3650587.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427177-112444_4470587.0RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427180-110305_3120475.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427180-110362_3650475.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427180-110444_4470475.0RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427674-111305_3120423.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427674-111362_3650423.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000427674-111444_4470423.0RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000431235-112305_3120423.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000431235-112362_3650423.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000431235-112444_4470423.0RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000449803-112305_3120423.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000449803-112362_3650423.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000449803-112444_4470423.0RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000541152-110305_3120336.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000541152-110362_3650336.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000541152-110444_4470336.0RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000585930-110305_3120363.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000585930-110362_3650363.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000585930-110444_4470363.0RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000588690-112305_3120512.6666666666666RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000588690-112362_3650512.6666666666666RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000588690-112444_4470512.6666666666666RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000590294-112305_3120354.3333333333333RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000590294-112362_3650354.3333333333333RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000590294-112444_4470354.3333333333333RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000591088-110305_3120336.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000591088-110362_3650336.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000591088-110444_4470336.0RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000591198-111305_3120568.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000591198-111362_3650568.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000591198-111444_4470568.0RegionG4 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000592951-110305_3120336.0RegionG1 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000592951-110362_3650336.0RegionG3 motif
HgeneSEPT9chr17:75369634chr19:6836443ENST00000592951-110444_4470336.0RegionG4 motif
TgeneVAV1chr17:75369634chr19:6836443ENST00000596764172633_99560814.0Compositional biasNote=Leu-rich
TgeneVAV1chr17:75369634chr19:6836443ENST00000602142182733_99592846.0Compositional biasNote=Leu-rich
TgeneVAV1chr17:75369634chr19:6836443ENST000005967641726194_373560814.0DomainDH
TgeneVAV1chr17:75369634chr19:6836443ENST0000059676417261_119560814.0DomainCalponin-homology (CH)
TgeneVAV1chr17:75369634chr19:6836443ENST000005967641726402_504560814.0DomainPH
TgeneVAV1chr17:75369634chr19:6836443ENST000006021421827194_373592846.0DomainDH
TgeneVAV1chr17:75369634chr19:6836443ENST0000060214218271_119592846.0DomainCalponin-homology (CH)
TgeneVAV1chr17:75369634chr19:6836443ENST000006021421827402_504592846.0DomainPH
TgeneVAV1chr17:75369634chr19:6836443ENST000005967641726515_564560814.0Zinc fingerPhorbol-ester/DAG-type
TgeneVAV1chr17:75369634chr19:6836443ENST000006021421827515_564592846.0Zinc fingerPhorbol-ester/DAG-type


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Fusion Gene Sequence for SEPT9-VAV1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80538_80538_1_SEPT9-VAV1_SEPT9_chr17_75369634_ENST00000423034_VAV1_chr19_6836443_ENST00000304076_length(transcript)=1317nt_BP=363nt
CCCCAGGCCTGGCCTTGACAGGCGGGCGGAGCAGCCAGTGCGAGACAGGGAGGCCGGTGCGGGTGCGGGAACCTGATCCGCCCGGGAGGC
GGGGGCGGGGCGGGGGCGCAGCGCGCGGGGAGGGGCCGGCGCCCGCCTTCCTCCCCCATTCATTCAGCTGAGCCAGGGGGCCTAGGGGCT
CCTCCGGCGGCTAGCTCTGCACTGCAGGAGCGCGGGCGCGGCGCCCCAGCCAGCGCGCAGGGCCCGGGCCCCGCCGGGGGCGCTTCCTCG
CCGCTGCCCTCCGCGCGACCCGCTGCCCACCAGCCATCATGTCGGACCCCGCGGTCAACGCGCAGCTGGATGGGATCATTTCGGACTTCG
AAGGTCTGCCCAAGATGGAGGTGTTTCAGGAATACTACGGGCTTCCTCCACCCCCTGGAGCCATTGGACCCTTTCTACGGCTCAACCCTG
GAGACATTGTGGAGCTCACGAAGGCTGAGGCTGAACAGAACTGGTGGGAGGGCCCTCCTCAGGACCTGTCTGTTCATCTCTGGTACGCAG
GCCCCATGGAGCGGGCAGGGGCAGAGAGCATCCTGGCCAACCGCTCGGACGGGACTTTCTTGGTGCGGCAGAGGGTGAAGGATGCAGCAG
AATTTGCCATCAGCATTAAATATAACGTCGAGGTCAAGCACATTAAAATCATGACAGCAGAAGGACTGTACCGGATCACAGAGAAAAAGG
CTTTCCGGGGGCTTACGGAGCTGGTGGAGTTTTACCAGCAGAACTCTCTAAAGGATTGCTTCAAGTCTCTGGACACCACCTTGCAGTTCC
CCTTCAAGGAGCCTGAAAAGAGAACCATCAGCAGGCCAGCAGTGGGAAGCACAAAGTATTTTGGCACAGCCAAAGCCCGCTATGACTTCT
GCGCCCGAGACCGATCAGAGCTGTCGCTCAAGGAGGGTGACATCATCAAGATCCTTAACAAGAAGGGACAGCAAGGCTGGTGGCGAGGGG
AGATCTATGGCCGGGTTGGCTGGTTCCCTGCCAACTACGTGGAGGAAGATTATTCTGAATACTGCTGAGCCCTGGTGCCTTGGCAGAGAG
ACGAGAAACTCCAGGCTCTGAGCCCGGCGTGGGCAGGCAGCGGAGCCAGGGGCTGTGACAGCTCCCGGCGGGTGGAGACTTTGGGATGGA
CTGGAGGAGGCCAGCGTCCAGCTGGCGGTGCTCCCGGGATGTGCCCTGACATGGTTAATTTATAACACCCCGATTTCCTCTTGGGTCCCC

>80538_80538_1_SEPT9-VAV1_SEPT9_chr17_75369634_ENST00000423034_VAV1_chr19_6836443_ENST00000304076_length(amino acids)=249AA_BP=18
MSDPAVNAQLDGIISDFEGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGPPQDLSVHLWYAGPMERAGAESILA
NRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISRP

--------------------------------------------------------------
>80538_80538_2_SEPT9-VAV1_SEPT9_chr17_75369634_ENST00000423034_VAV1_chr19_6836443_ENST00000539284_length(transcript)=1377nt_BP=363nt
CCCCAGGCCTGGCCTTGACAGGCGGGCGGAGCAGCCAGTGCGAGACAGGGAGGCCGGTGCGGGTGCGGGAACCTGATCCGCCCGGGAGGC
GGGGGCGGGGCGGGGGCGCAGCGCGCGGGGAGGGGCCGGCGCCCGCCTTCCTCCCCCATTCATTCAGCTGAGCCAGGGGGCCTAGGGGCT
CCTCCGGCGGCTAGCTCTGCACTGCAGGAGCGCGGGCGCGGCGCCCCAGCCAGCGCGCAGGGCCCGGGCCCCGCCGGGGGCGCTTCCTCG
CCGCTGCCCTCCGCGCGACCCGCTGCCCACCAGCCATCATGTCGGACCCCGCGGTCAACGCGCAGCTGGATGGGATCATTTCGGACTTCG
AAGGTCTGCCCAAGATGGAGGTGTTTCAGGAATACTACGGGCTTCCTCCACCCCCTGGAGCCATTGGACCCTTTCTACGGCTCAACCCTG
GAGACATTGTGGAGCTCACGAAGGCTGAGGCTGAACAGAACTGGTGGGAGGGCAGAAATACATCTACTAATGAAATTGGCTGGTTTCCTT
GTAACAGGGTGAAGCCCTATGTCCATGGCCCTCCTCAGGACCTGTCTGTTCATCTCTGGTACGCAGGCCCCATGGAGCGGGCAGGGGCAG
AGAGCATCCTGGCCAACCGCTCGGACGGGACTTTCTTGGTGCGGCAGAGGGTGAAGGATGCAGCAGAATTTGCCATCAGCATTAAATATA
ACGTCGAGGTCAAGCACATTAAAATCATGACAGCAGAAGGACTGTACCGGATCACAGAGAAAAAGGCTTTCCGGGGGCTTACGGAGCTGG
TGGAGTTTTACCAGCAGAACTCTCTAAAGGATTGCTTCAAGTCTCTGGACACCACCTTGCAGTTCCCCTTCAAGGAGCCTGAAAAGAGAA
CCATCAGCAGGCCAGCAGTGGGAAGCACAAAGTATTTTGGCACAGCCAAAGCCCGCTATGACTTCTGCGCCCGAGACCGATCAGAGCTGT
CGCTCAAGGAGGGTGACATCATCAAGATCCTTAACAAGAAGGGACAGCAAGGCTGGTGGCGAGGGGAGATCTATGGCCGGGTTGGCTGGT
TCCCTGCCAACTACGTGGAGGAAGATTATTCTGAATACTGCTGAGCCCTGGTGCCTTGGCAGAGAGACGAGAAACTCCAGGCTCTGAGCC
CGGCGTGGGCAGGCAGCGGAGCCAGGGGCTGTGACAGCTCCCGGCGGGTGGAGACTTTGGGATGGACTGGAGGAGGCCAGCGTCCAGCTG
GCGGTGCTCCCGGGATGTGCCCTGACATGGTTAATTTATAACACCCCGATTTCCTCTTGGGTCCCCTCAAGCAGACGGGGCTCAAGGGGG

>80538_80538_2_SEPT9-VAV1_SEPT9_chr17_75369634_ENST00000423034_VAV1_chr19_6836443_ENST00000539284_length(amino acids)=271AA_BP=18
MSDPAVNAQLDGIISDFEGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQ
DLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCF
KSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEY

--------------------------------------------------------------
>80538_80538_3_SEPT9-VAV1_SEPT9_chr17_75369634_ENST00000423034_VAV1_chr19_6836443_ENST00000596764_length(transcript)=1377nt_BP=363nt
CCCCAGGCCTGGCCTTGACAGGCGGGCGGAGCAGCCAGTGCGAGACAGGGAGGCCGGTGCGGGTGCGGGAACCTGATCCGCCCGGGAGGC
GGGGGCGGGGCGGGGGCGCAGCGCGCGGGGAGGGGCCGGCGCCCGCCTTCCTCCCCCATTCATTCAGCTGAGCCAGGGGGCCTAGGGGCT
CCTCCGGCGGCTAGCTCTGCACTGCAGGAGCGCGGGCGCGGCGCCCCAGCCAGCGCGCAGGGCCCGGGCCCCGCCGGGGGCGCTTCCTCG
CCGCTGCCCTCCGCGCGACCCGCTGCCCACCAGCCATCATGTCGGACCCCGCGGTCAACGCGCAGCTGGATGGGATCATTTCGGACTTCG
AAGGTCTGCCCAAGATGGAGGTGTTTCAGGAATACTACGGGCTTCCTCCACCCCCTGGAGCCATTGGACCCTTTCTACGGCTCAACCCTG
GAGACATTGTGGAGCTCACGAAGGCTGAGGCTGAACAGAACTGGTGGGAGGGCAGAAATACATCTACTAATGAAATTGGCTGGTTTCCTT
GTAACAGGGTGAAGCCCTATGTCCATGGCCCTCCTCAGGACCTGTCTGTTCATCTCTGGTACGCAGGCCCCATGGAGCGGGCAGGGGCAG
AGAGCATCCTGGCCAACCGCTCGGACGGGACTTTCTTGGTGCGGCAGAGGGTGAAGGATGCAGCAGAATTTGCCATCAGCATTAAATATA
ACGTCGAGGTCAAGCACATTAAAATCATGACAGCAGAAGGACTGTACCGGATCACAGAGAAAAAGGCTTTCCGGGGGCTTACGGAGCTGG
TGGAGTTTTACCAGCAGAACTCTCTAAAGGATTGCTTCAAGTCTCTGGACACCACCTTGCAGTTCCCCTTCAAGGAGCCTGAAAAGAGAA
CCATCAGCAGGCCAGCAGTGGGAAGCACAAAGTATTTTGGCACAGCCAAAGCCCGCTATGACTTCTGCGCCCGAGACCGATCAGAGCTGT
CGCTCAAGGAGGGTGACATCATCAAGATCCTTAACAAGAAGGGACAGCAAGGCTGGTGGCGAGGGGAGATCTATGGCCGGGTTGGCTGGT
TCCCTGCCAACTACGTGGAGGAAGATTATTCTGAATACTGCTGAGCCCTGGTGCCTTGGCAGAGAGACGAGAAACTCCAGGCTCTGAGCC
CGGCGTGGGCAGGCAGCGGAGCCAGGGGCTGTGACAGCTCCCGGCGGGTGGAGACTTTGGGATGGACTGGAGGAGGCCAGCGTCCAGCTG
GCGGTGCTCCCGGGATGTGCCCTGACATGGTTAATTTATAACACCCCGATTTCCTCTTGGGTCCCCTCAAGCAGACGGGGCTCAAGGGGG

>80538_80538_3_SEPT9-VAV1_SEPT9_chr17_75369634_ENST00000423034_VAV1_chr19_6836443_ENST00000596764_length(amino acids)=271AA_BP=18
MSDPAVNAQLDGIISDFEGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQ
DLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCF
KSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEY

--------------------------------------------------------------
>80538_80538_4_SEPT9-VAV1_SEPT9_chr17_75369634_ENST00000423034_VAV1_chr19_6836443_ENST00000599806_length(transcript)=1383nt_BP=363nt
CCCCAGGCCTGGCCTTGACAGGCGGGCGGAGCAGCCAGTGCGAGACAGGGAGGCCGGTGCGGGTGCGGGAACCTGATCCGCCCGGGAGGC
GGGGGCGGGGCGGGGGCGCAGCGCGCGGGGAGGGGCCGGCGCCCGCCTTCCTCCCCCATTCATTCAGCTGAGCCAGGGGGCCTAGGGGCT
CCTCCGGCGGCTAGCTCTGCACTGCAGGAGCGCGGGCGCGGCGCCCCAGCCAGCGCGCAGGGCCCGGGCCCCGCCGGGGGCGCTTCCTCG
CCGCTGCCCTCCGCGCGACCCGCTGCCCACCAGCCATCATGTCGGACCCCGCGGTCAACGCGCAGCTGGATGGGATCATTTCGGACTTCG
AAGGTCTGCCCAAGATGGAGGTGTTTCAGGAATACTACGGGCTTCCTCCACCCCCTGGAGCCATTGGACCCTTTCTACGGCTCAACCCTG
GAGACATTGTGGAGCTCACGAAGGCTGAGGCTGAACAGAACTGGTGGGAGGGCAGAAATACATCTACTAATGAAATTGGCTGGTTTCCTT
GTAACAGGGTGAAGCCCTATGTCCATGGCCCTCCTCAGGACCTGTCTGTTCATCTCTGGTACGCAGGCCCCATGGAGCGGGCAGGGGCAG
AGAGCATCCTGGCCAACCGCTCGGACGGGACTTTCTTGGTGCGGCAGAGGGTGAAGGATGCAGCAGAATTTGCCATCAGCATTAAATATA
ACGTCGAGGTCAAGCACATTAAAATCATGACAGCAGAAGGACTGTACCGGATCACAGAGAAAAAGGCTTTCCGGGGGCTTACGGAGCTGG
TGGAGTTTTACCAGCAGAACTCTCTAAAGGATTGCTTCAAGTCTCTGGACACCACCTTGCAGTTCCCCTTCAAGGAGCCTGAAAAGAGAA
CCATCAGCAGGCCAGCAGTGGGAAGCACAAAGTATTTTGGCACAGCCAAAGCCCGCTATGACTTCTGCGCCCGAGACCGATCAGAGCTGT
CGCTCAAGGAGGGTGACATCATCAAGATCCTTAACAAGAAGGGACAGCAAGGCTGGTGGCGAGGGGAGATCTATGGCCGGGTTGGCTGGT
TCCCTGCCAACTACGTGGAGGAAGATTATTCTGAATACTGCTGAGCCCTGGTGCCTTGGCAGAGAGACGAGAAACTCCAGGCTCTGAGCC
CGGCGTGGGCAGGCAGCGGAGCCAGGGGCTGTGACAGCTCCCGGCGGGTGGAGACTTTGGGATGGACTGGAGGAGGCCAGCGTCCAGCTG
GCGGTGCTCCCGGGATGTGCCCTGACATGGTTAATTTATAACACCCCGATTTCCTCTTGGGTCCCCTCAAGCAGACGGGGCTCAAGGGGG

>80538_80538_4_SEPT9-VAV1_SEPT9_chr17_75369634_ENST00000423034_VAV1_chr19_6836443_ENST00000599806_length(amino acids)=271AA_BP=18
MSDPAVNAQLDGIISDFEGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQ
DLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCF
KSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEY

--------------------------------------------------------------
>80538_80538_5_SEPT9-VAV1_SEPT9_chr17_75369634_ENST00000423034_VAV1_chr19_6836443_ENST00000602142_length(transcript)=1124nt_BP=363nt
CCCCAGGCCTGGCCTTGACAGGCGGGCGGAGCAGCCAGTGCGAGACAGGGAGGCCGGTGCGGGTGCGGGAACCTGATCCGCCCGGGAGGC
GGGGGCGGGGCGGGGGCGCAGCGCGCGGGGAGGGGCCGGCGCCCGCCTTCCTCCCCCATTCATTCAGCTGAGCCAGGGGGCCTAGGGGCT
CCTCCGGCGGCTAGCTCTGCACTGCAGGAGCGCGGGCGCGGCGCCCCAGCCAGCGCGCAGGGCCCGGGCCCCGCCGGGGGCGCTTCCTCG
CCGCTGCCCTCCGCGCGACCCGCTGCCCACCAGCCATCATGTCGGACCCCGCGGTCAACGCGCAGCTGGATGGGATCATTTCGGACTTCG
AAGGTCTGCCCAAGATGGAGGTGTTTCAGGAATACTACGGGCTTCCTCCACCCCCTGGAGCCATTGGACCCTTTCTACGGCTCAACCCTG
GAGACATTGTGGAGCTCACGAAGGCTGAGGCTGAACAGAACTGGTGGGAGGGCAGAAATACATCTACTAATGAAATTGGCTGGTTTCCTT
GTAACAGGGTGAAGCCCTATGTCCATGGCCCTCCTCAGGACCTGTCTGTTCATCTCTGGTACGCAGGCCCCATGGAGCGGGCAGGGGCAG
AGAGCATCCTGGCCAACCGCTCGGACGGGACTTTCTTGGTGCGGCAGAGGGTGAAGGATGCAGCAGAATTTGCCATCAGCATTAAATATA
ACGTCGAGGTCAAGCACATTAAAATCATGACAGCAGAAGGACTGTACCGGATCACAGAGAAAAAGGCTTTCCGGGGGCTTACGGAGCTGG
TGGAGTTTTACCAGCAGAACTCTCTAAAGGATTGCTTCAAGTCTCTGGACACCACCTTGCAGTTCCCCTTCAAGGAGCCTGAAAAGAGAA
CCATCAGCAGGCCAGCAGTGGGAAGCACAAAGTATTTTGGCACAGCCAAAGCCCGCTATGACTTCTGCGCCCGAGACCGATCAGAGCTGT
CGCTCAAGGAGGGTGACATCATCAAGATCCTTAACAAGAAGGGACAGCAAGGCTGGTGGCGAGGGGAGATCTATGGCCGGGTTGGCTGGT

>80538_80538_5_SEPT9-VAV1_SEPT9_chr17_75369634_ENST00000423034_VAV1_chr19_6836443_ENST00000602142_length(amino acids)=272AA_BP=18
MSDPAVNAQLDGIISDFEGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQ
DLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCF
KSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEY

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SEPT9-VAV1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SEPT9-VAV1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SEPT9-VAV1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource