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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SERINC5-MYO10 (FusionGDB2 ID:80690)

Fusion Gene Summary for SERINC5-MYO10

check button Fusion gene summary
Fusion gene informationFusion gene name: SERINC5-MYO10
Fusion gene ID: 80690
HgeneTgene
Gene symbol

SERINC5

MYO10

Gene ID

256987

4651

Gene nameserine incorporator 5myosin X
SynonymsC5orf12|TPO1-
Cytomap

5q14.1

5p15.1

Type of geneprotein-codingprotein-coding
Descriptionserine incorporator 5unconventional myosin-Xunconventional myosin-10unconventionnal myosin-X
Modification date2020031320200313
UniProtAcc.

Q9HD67

Ensembl transtripts involved in fusion geneENST00000507668, ENST00000509193, 
ENST00000512721, ENST00000512972, 
ENST00000513907, 		ENST00000512061, 
ENST00000274203, ENST00000427430, 
ENST00000505695, ENST00000507288, 
ENST00000515803, ENST00000513610, 
Fusion gene scores* DoF score15 X 10 X 9=13509 X 11 X 4=396
# samples 1611
** MAII scorelog2(16/1350*10)=-3.07681559705083
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/396*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SERINC5 [Title/Abstract] AND MYO10 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSERINC5(79498705)-MYO10(16704794), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSERINC5

GO:0009597

detection of virus

26416733|26416734

HgeneSERINC5

GO:0045087

innate immune response

26416733|26416734

HgeneSERINC5

GO:0051607

defense response to virus

26416733|26416734


check buttonFusion gene breakpoints across SERINC5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MYO10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-FW-A3I3-06ASERINC5chr5

79498705

-MYO10chr5

16704794

-


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Fusion Gene ORF analysis for SERINC5-MYO10

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000507668ENST00000512061SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-5UTRENST00000509193ENST00000512061SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-5UTRENST00000512721ENST00000512061SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-5UTRENST00000512972ENST00000512061SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000507668ENST00000274203SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000507668ENST00000427430SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000507668ENST00000505695SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000507668ENST00000507288SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000507668ENST00000515803SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000509193ENST00000274203SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000509193ENST00000427430SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000509193ENST00000505695SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000509193ENST00000507288SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000509193ENST00000515803SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000512721ENST00000274203SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000512721ENST00000427430SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000512721ENST00000505695SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000512721ENST00000507288SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000512721ENST00000515803SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000512972ENST00000274203SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000512972ENST00000427430SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000512972ENST00000505695SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000512972ENST00000507288SERINC5chr5

79498705

-MYO10chr5

16704794

-
5CDS-intronENST00000512972ENST00000515803SERINC5chr5

79498705

-MYO10chr5

16704794

-
5UTR-3CDSENST00000513907ENST00000513610SERINC5chr5

79498705

-MYO10chr5

16704794

-
5UTR-5UTRENST00000513907ENST00000512061SERINC5chr5

79498705

-MYO10chr5

16704794

-
5UTR-intronENST00000513907ENST00000274203SERINC5chr5

79498705

-MYO10chr5

16704794

-
5UTR-intronENST00000513907ENST00000427430SERINC5chr5

79498705

-MYO10chr5

16704794

-
5UTR-intronENST00000513907ENST00000505695SERINC5chr5

79498705

-MYO10chr5

16704794

-
5UTR-intronENST00000513907ENST00000507288SERINC5chr5

79498705

-MYO10chr5

16704794

-
5UTR-intronENST00000513907ENST00000515803SERINC5chr5

79498705

-MYO10chr5

16704794

-
In-frameENST00000507668ENST00000513610SERINC5chr5

79498705

-MYO10chr5

16704794

-
In-frameENST00000509193ENST00000513610SERINC5chr5

79498705

-MYO10chr5

16704794

-
In-frameENST00000512721ENST00000513610SERINC5chr5

79498705

-MYO10chr5

16704794

-
In-frameENST00000512972ENST00000513610SERINC5chr5

79498705

-MYO10chr5

16704794

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000507668SERINC5chr579498705-ENST00000513610MYO10chr516704794-576034613943531404
ENST00000512972SERINC5chr579498705-ENST00000513610MYO10chr516704794-57062928542991404
ENST00000509193SERINC5chr579498705-ENST00000513610MYO10chr516704794-57062928542991404
ENST00000512721SERINC5chr579498705-ENST00000513610MYO10chr516704794-576635214543591404

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000507668ENST00000513610SERINC5chr579498705-MYO10chr516704794-0.0010406040.9989594
ENST00000512972ENST00000513610SERINC5chr579498705-MYO10chr516704794-0.0009910520.9990089
ENST00000509193ENST00000513610SERINC5chr579498705-MYO10chr516704794-0.0009910520.9990089
ENST00000512721ENST00000513610SERINC5chr579498705-MYO10chr516704794-0.0010198020.9989802

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Fusion Genomic Features for SERINC5-MYO10


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SERINC5-MYO10


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:79498705/chr5:16704794)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MYO10

Q9HD67

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. In hippocampal neurons it induces the formation of dendritic filopodia by trafficking the actin-remodeling protein VASP to the tips of filopodia, where it promotes actin elongation. Plays a role in formation of the podosome belt in osteoclasts. {ECO:0000269|PubMed:16894163, ECO:0000269|PubMed:18570893}.; FUNCTION: [Isoform Headless]: Functions as a dominant-negative regulator of isoform 1, suppressing its filopodia-inducing and axon outgrowth-promoting activities. In hippocampal neurons, it increases VASP retention in spine heads to induce spine formation and spine head expansion (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-2135_2665488.3333333333333Compositional biasNote=Cys-rich
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-2125_2665462.0Compositional biasNote=Cys-rich
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-2145_2665358.3333333333333Compositional biasNote=Cys-rich
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-2131_3665488.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-2121_3665462.0Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-2141_3665358.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-21337_5765488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-21237_5765462.0TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-21437_5765358.3333333333333TransmembraneHelical
TgeneMYO10chr5:79498705chr5:16704794ENST0000051361020411212_13107232059.0DomainPH 1
TgeneMYO10chr5:79498705chr5:16704794ENST0000051361020411392_14977232059.0DomainPH 2
TgeneMYO10chr5:79498705chr5:16704794ENST0000051361020411547_16957232059.0DomainMyTH4
TgeneMYO10chr5:79498705chr5:16704794ENST0000051361020411700_20447232059.0DomainFERM
TgeneMYO10chr5:79498705chr5:16704794ENST000005136102041742_7637232059.0DomainIQ 1
TgeneMYO10chr5:79498705chr5:16704794ENST000005136102041764_7877232059.0DomainIQ 2
TgeneMYO10chr5:79498705chr5:16704794ENST000005136102041788_8177232059.0DomainIQ 3
TgeneMYO10chr5:79498705chr5:16704794ENST000005136102041815_9087232059.0RegionSAH
TgeneMYO10chr5:79498705chr5:16704794ENST000005136102041883_9337232059.0RegionMediates antiparallel dimerization

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213111_12465488.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213146_15665488.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213178_19865488.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213220_23065488.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213252_25865488.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213280_31165488.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213333_38565488.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213407_42365488.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-21358_8965488.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212111_12465462.0Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212146_15665462.0Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212178_19865462.0Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212220_23065462.0Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212252_25865462.0Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212280_31165462.0Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212333_38565462.0Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212407_42365462.0Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-21258_8965462.0Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214111_12465358.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214146_15665358.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214178_19865358.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214220_23065358.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214252_25865358.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214280_31165358.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214333_38565358.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214407_42365358.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-21458_8965358.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213125_14565488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213157_17765488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213199_21965488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213231_25165488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213259_27965488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213312_33265488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-213386_40665488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000507668-21390_11065488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212125_14565462.0TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212157_17765462.0TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212199_21965462.0TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212231_25165462.0TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212259_27965462.0TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212312_33265462.0TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-212386_40665462.0TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512721-21290_11065462.0TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214125_14565358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214157_17765358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214199_21965358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214231_25165358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214259_27965358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214312_33265358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-214386_40665358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79498705chr5:16704794ENST00000512972-21490_11065358.3333333333333TransmembraneHelical
TgeneMYO10chr5:79498705chr5:16704794ENST00000513610204163_7397232059.0DomainMyosin motor
TgeneMYO10chr5:79498705chr5:16704794ENST000005136102041157_1647232059.0Nucleotide bindingATP
TgeneMYO10chr5:79498705chr5:16704794ENST000005136102041619_6417232059.0RegionActin-binding


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Fusion Gene Sequence for SERINC5-MYO10


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80690_80690_1_SERINC5-MYO10_SERINC5_chr5_79498705_ENST00000507668_MYO10_chr5_16704794_ENST00000513610_length(transcript)=5760nt_BP=346nt
ACCCAGGCCTCGGCGCCTAGGCGCTTCGCCGAGGCTGATCTTCGTTCAAGTGTGAGCTGCGGCTGAGCCCAGCGCTCGAGGCGCGAGGCA
GCCAGGAGGGCCCGTGCGGCGCGGGGAGCCAGCGAGCGCGCCTTCGGCATTGGCCGCCGCGATGTCAGCTCAGTGCTGTGCGGGCCAGCT
GGCCTGCTGCTGTGGGTCTGCAGGCTGCTCTCTCTGCTGTGATTGCTGCCCCAGGATTCGGCAGTCCCTCAGCACCCGCTTCATGTACGC
CCTCTACTTCATTCTGGTCGTCGTCCTCTGCTGCATCATGATGTCAACAACCGTGGCTCACAAGATGAAAGAGCACGTCTTTCTTCGAGA
ATCCTTGGAACAGAAACTGGAGAAGCGGAGGGAAGAGGAAGTGAGCCACGCGGCCATGGTGATTCGGGCCCATGTCTTGGGCTTCTTAGC
ACGAAAACAATACAGAAAGGTCCTTTATTGTGTGGTGATAATACAGAAGAATTACAGAGCATTCCTTCTGAGGAGGAGATTTTTGCACCT
GAAAAAGGCAGCCATAGTTTTCCAGAAGCAACTCAGAGGTCAGATTGCTCGGAGAGTTTACAGACAATTGCTGGCAGAGAAAAGGGAGCA
AGAAGAAAAGAAGAAACAGGAAGAGGAAGAAAAGAAGAAACGGGAGGAAGAAGAAAGAGAAAGAGAGAGAGAGCGAAGAGAAGCCGAGCT
CCGCGCCCAGCAGGAAGAAGAAACGAGGAAGCAGCAAGAACTCGAAGCCTTGCAGAAGAGCCAGAAGGAAGCTGAACTGACCCGTGAACT
GGAGAAACAGAAGGAAAATAAGCAGGTGGAAGAGATCCTCCGTCTGGAGAAAGAAATCGAGGACCTGCAGCGCATGAAGGAGCAGCAGGA
GCTGTCGCTGACCGAGGCTTCCCTGCAGAAGCTGCAGGAGCGGCGGGACCAGGAGCTCCGCAGGCTGGAGGAGGAAGCGTGCAGGGCGGC
CCAGGAGTTCCTCGAGTCCCTCAATTTCGACGAGATCGACGAGTGTGTCCGGAATATCGAGCGGTCCCTGTCGGTGGGAAGCGAATTTTC
CAGCGAGCTGGCTGAGAGCGCATGCGAGGAGAAGCCCAACTTCAACTTCAGCCAGCCCTACCCAGAGGAGGAGGTCGATGAGGGCTTCGA
AGCCGACGACGACGCCTTCAAGGACTCCCCCAACCCCAGCGAGCACGGCCACTCAGACCAGCGAACAAGTGGCATCCGGACCAGCGATGA
CTCTTCAGAGGAGGACCCATACATGAACGACACGGTGGTGCCCACCAGCCCCAGTGCGGACAGCACGGTGCTGCTCGCCCCATCAGTGCA
GGACTCCGGGAGCCTACACAACTCCTCCAGCGGCGAGTCCACCTACTGCATGCCCCAGAACGCTGGGGACTTGCCCTCCCCAGACGGCGA
CTACGACTACGACCAGGATGACTATGAGGACGGTGCCATCACTTCCGGCAGCAGCGTGACCTTCTCCAACTCCTACGGCAGCCAGTGGTC
CCCCGACTACCGCTGCTCTGTGGGGACCTACAACAGCTCGGGTGCCTACCGGTTCAGCTCTGAGGGGGCGCAGTCCTCGTTTGAAGATAG
TGAAGAGGACTTTGATTCCAGGTTTGATACAGATGATGAGCTTTCATACCGGCGTGACTCTGTGTACAGCTGTGTCACTCTGCCGTATTT
CCACAGCTTTCTGTACATGAAAGGTGGCCTGATGAACTCTTGGAAACGCCGCTGGTGCGTCCTCAAGGATGAAACCTTCTTGTGGTTCCG
CTCCAAGCAGGAGGCCCTCAAGCAAGGCTGGCTCCACAAAAAAGGGGGGGGCTCCTCCACGCTGTCCAGGAGAAATTGGAAGAAGCGCTG
GTTTGTCCTCCGCCAGTCCAAGCTGATGTACTTTGAAAACGACAGCGAGGAGAAGCTCAAGGGCACCGTAGAAGTGCGAACGGCAAAAGA
GATCATAGATAACACCACCAAGGAGAATGGGATCGACATCATTATGGCCGATAGGACTTTCCACCTGATTGCAGAGTCCCCAGAAGATGC
CAGCCAGTGGTTCAGCGTGCTGAGTCAGGTCCACGCGTCCACGGACCAGGAGATCCAGGAGATGCATGATGAGCAGGCAAACCCACAGAA
TGCTGTGGGCACCTTGGATGTGGGGCTGATTGATTCTGTGTGTGCCTCTGACAGCCCTGATAGACCCAACTCGTTTGTGATCATCACGGC
CAACCGGGTGCTGCACTGCAACGCCGACACGCCGGAGGAGATGCACCACTGGATAACCCTGCTGCAGAGGTCCAAAGGGGACACCAGAGT
GGAGGGCCAGGAATTCATCGTGAGAGGATGGTTGCACAAAGAGGTGAAGAACAGTCCAAAGATGTCTTCACTGAAACTGAAGAAACGGTG
GTTTGTACTCACCCACAATTCCCTGGATTACTACAAGAGTTCAGAGAAGAACGCGCTCAAACTGGGGACCCTGGTCCTCAACAGCCTCTG
CTCTGTCGTCCCCCCAGATGAGAAGATATTCAAAGAGACAGGCTACTGGAACGTCACCGTGTACGGGCGCAAGCACTGTTACCGGCTCTA
CACCAAGCTGCTCAACGAGGCCACCCGGTGGTCCAGTGCCATTCAAAACGTGACTGACACCAAGGCCCCGATCGACACCCCCACCCAGCA
GCTGATTCAAGATATCAAGGAGAACTGCCTGAACTCGGATGTGGTGGAACAGATTTACAAGCGGAACCCGATCCTTCGATACACCCATCA
CCCCTTGCACTCCCCGCTCCTGCCCCTTCCGTATGGGGACATAAATCTCAACTTGCTCAAAGACAAAGGCTATACCACCCTTCAGGATGA
GGCCATCAAGATATTCAATTCCCTGCAGCAACTGGAGTCCATGTCTGACCCAATTCCAATAATCCAGGGCATCCTACAGACAGGGCATGA
CCTGCGACCTCTGCGGGACGAGCTGTACTGCCAGCTTATCAAACAGACCAACAAAGTGCCCCACCCCGGCAGTGTGGGCAACCTGTACAG
CTGGCAGATCCTGACATGCCTGAGCTGCACCTTCCTGCCGAGTCGAGGGATTCTCAAGTATCTCAAGTTCCATCTGAAAAGGATACGGGA
ACAGTTTCCAGGAAGCGAGATGGAAAAATACGCTCTCTTCACTTACGAATCTCTTAAGAAAACCAAATGCCGAGAGTTTGTGCCTTCCCG
AGATGAAATAGAAGCTCTGATCCACAGGCAGGAAATGACATCCACGGTCTATTGCCATGGCGGCGGCTCCTGCAAGATCACCATCAACTC
CCACACCACCGCTGGGGAGGTGGTGGAGAAGCTGATCCGAGGCCTGGCCATGGAGGACAGCAGGAACATGTTTGCTTTGTTTGAATACAA
CGGCCACGTCGACAAAGCCATTGAAAGTCGAACCGTCGTAGCTGATGTCTTAGCCAAGTTTGAAAAGCTGGCTGCCACATCCGAGGTTGG
GGACCTGCCATGGAAATTCTACTTCAAACTTTACTGCTTCCTGGACACAGACAACGTGCCAAAAGACAGTGTGGAGTTTGCATTTATGTT
TGAACAGGCCCACGAAGCGGTTATCCATGGCCACCATCCAGCCCCGGAAGAAAACCTCCAGGTTCTTGCTGCCCTGCGACTCCAGTATCT
GCAGGGGGATTATACTCTGCACGCTGCCATCCCACCTCTCGAAGAGGTTTATTCCCTGCAGAGACTCAAGGCCCGCATCAGCCAGTCAAC
CAAAACCTTCACCCCTTGTGAACGGCTGGAGAAGAGGCGGACGAGCTTCCTAGAGGGGACCCTGAGGCGGAGCTTCCGGACAGGATCCGT
GGTCCGGCAGAAGGTCGAGGAGGAGCAGATGCTGGACATGTGGATTAAGGAAGAAGTCTCCTCTGCTCGAGCCAGTATCATTGACAAGTG
GAGGAAATTTCAGGGAATGAACCAGGAACAGGCCATGGCCAAGTACATGGCCTTGATCAAGGAGTGGCCTGGCTATGGCTCGACGCTGTT
TGATGTGGAGTGCAAGGAAGGTGGCTTCCCTCAGGAACTCTGGTTGGGTGTCAGCGCGGACGCCGTCTCCGTCTACAAGCGTGGAGAGGG
AAGACCACTGGAAGTCTTCCAGTATGAACACATCCTCTCTTTTGGGGCACCCCTGGCGAATACGTATAAGATCGTGGTCGATGAGAGGGA
GCTGCTCTTTGAAACCAGTGAGGTGGTGGATGTGGCCAAGCTCATGAAAGCCTACATCAGCATGATCGTGAAGAAGCGCTACAGCACGAC
ACGCTCCGCCAGCAGCCAGGGCAGCTCCAGGTGAAGGCGGGACAGAGCCCACCTGTCTTTGCTACCTGAACGCACCACCCTCTGGCCTAG
GCTGGCTCCAGTGTGCCATGCCCAGCCAAAACAAACACAGAGCTGCCCAGGCTTTCTGGAAGCTTCTGGTCTGAGGGAGGTGTCTCCGAG
GATCCTTTTGCCTGCCGCCTTCATTGATCCTGTATTAAGCTGTCAACTTTAACAGTCTGCACAGTTTCCAAAGCTTTACTACTCTTAGAG
GACACATGCCTTAAAAAAGGAGGGGAGGAACCACGCTGCCACCAAAGCAGCCGGAAGTGCCTTAACTTGTGGAACCAACACTAATCGACC
GTAACTGTGCTACTGAAGGGAACTGCCTTTCCCCCTTCTGGGGGAGACTTAACAGAGCGTGGAAGGGGGGCATTCTCTGTCAATGATGCA
CTAACCTCCCAACCTGATTTCCCCGAATCTGAGGGAAGGTGAGGGAGTGGGAAGGGGGATGGAGAGCTCGAGGGGACAGTGTGTTTGAGC
TGGAGTGCTGCGGGCAGCCTTTCTCATGGAATGACATGAATCAACTTTTTTCTTTGTTTCATCTTTTAAGTGTACGTGCTTGCCTGTTCG
TGCATGTGTTCATAAACTCAACACTTTAATCATGGTTTCATGAGCATTAAAAAGCAAAGGGAAAAAGGATGTGTAATGGTGTACACAGTC
TGTATATTTTAATAATGCAGAGCTATAGTCTCAATTGTTACTTTATAAGGTGGTTTTATTAACAAACCCAAATCCTGGATTTTCCTGTCT
TTGCTGTATTTTGAAAAACACGTGTTGACTCCATTGTTTTACATGTAGCAAAGTCTGCCATCTGTGTCTGCTGTATTATAAACAGATAAG
CAGCCTACAAGATAACTGTATTTATAAACCACTCTTCAACAGCTGGCTCCAGTGCTGGTTTTAGAACAAGAATGAAGTCATTTTGGAGTC
TTTCATGTCTAAAAGATTTAAGTTAAAAACAAAGTGTTACTTGGAAGGTTAGCTTCTATCATTCTGGATAGATTACAGATATAATAACCA
TGTTGACTATGGGGGAGAGACGCTGCATTCCAGAAACGTCTTAACACTTGAGTGAATCTTCAAAGGACCCTGACATTAAATGCTGAGGCT
TTAATACACACATATTTTATCCCAAGTTTATAATGGTGGTCTGAACAAGGCACCTGTAAATAAATCAGCATTTATGACCAGAAGAAAAAT
AATCTGGTCTTGGACTTTTTATTTTTATATGGAAAAGTTTTAAGGACTTGGGCCAACTAAGTCTACCCACACGAAAAAAGAAATTTGCCT
TGTCCCTTTGTGTACAACCATGCAAAACTGTTTGTTGGCTCACAGAAGTTCTGACAATAAAAGATACTAGCTAACACGCTGTGTGTTTCC

>80690_80690_1_SERINC5-MYO10_SERINC5_chr5_79498705_ENST00000507668_MYO10_chr5_16704794_ENST00000513610_length(amino acids)=1404AA_BP=67
MAAAMSAQCCAGQLACCCGSAGCSLCCDCCPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMKEHVFLRESLEQKLEKRREEEVSH
AAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREE
EERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRD
QELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEHG
HSDQRTSGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTYCMPQNAGDLPSPDGDYDYDQDDYEDGAITSG
SSVTFSNSYGSQWSPDYRCSVGTYNSSGAYRFSSEGAQSSFEDSEEDFDSRFDTDDELSYRRDSVYSCVTLPYFHSFLYMKGGLMNSWKR
RWCVLKDETFLWFRSKQEALKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEKLKGTVEVRTAKEIIDNTTKENGIDIIMA
DRTFHLIAESPEDASQWFSVLSQVHASTDQEIQEMHDEQANPQNAVGTLDVGLIDSVCASDSPDRPNSFVIITANRVLHCNADTPEEMHH
WITLLQRSKGDTRVEGQEFIVRGWLHKEVKNSPKMSSLKLKKRWFVLTHNSLDYYKSSEKNALKLGTLVLNSLCSVVPPDEKIFKETGYW
NVTVYGRKHCYRLYTKLLNEATRWSSAIQNVTDTKAPIDTPTQQLIQDIKENCLNSDVVEQIYKRNPILRYTHHPLHSPLLPLPYGDINL
NLLKDKGYTTLQDEAIKIFNSLQQLESMSDPIPIIQGILQTGHDLRPLRDELYCQLIKQTNKVPHPGSVGNLYSWQILTCLSCTFLPSRG
ILKYLKFHLKRIREQFPGSEMEKYALFTYESLKKTKCREFVPSRDEIEALIHRQEMTSTVYCHGGGSCKITINSHTTAGEVVEKLIRGLA
MEDSRNMFALFEYNGHVDKAIESRTVVADVLAKFEKLAATSEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPE
ENLQVLAALRLQYLQGDYTLHAAIPPLEEVYSLQRLKARISQSTKTFTPCERLEKRRTSFLEGTLRRSFRTGSVVRQKVEEEQMLDMWIK
EEVSSARASIIDKWRKFQGMNQEQAMAKYMALIKEWPGYGSTLFDVECKEGGFPQELWLGVSADAVSVYKRGEGRPLEVFQYEHILSFGA

--------------------------------------------------------------
>80690_80690_2_SERINC5-MYO10_SERINC5_chr5_79498705_ENST00000509193_MYO10_chr5_16704794_ENST00000513610_length(transcript)=5706nt_BP=292nt
AGCTGCGGCTGAGCCCAGCGCTCGAGGCGCGAGGCAGCCAGGAGGGCCCGTGCGGCGCGGGGAGCCAGCGAGCGCGCCTTCGGCATTGGC
CGCCGCGATGTCAGCTCAGTGCTGTGCGGGCCAGCTGGCCTGCTGCTGTGGGTCTGCAGGCTGCTCTCTCTGCTGTGATTGCTGCCCCAG
GATTCGGCAGTCCCTCAGCACCCGCTTCATGTACGCCCTCTACTTCATTCTGGTCGTCGTCCTCTGCTGCATCATGATGTCAACAACCGT
GGCTCACAAGATGAAAGAGCACGTCTTTCTTCGAGAATCCTTGGAACAGAAACTGGAGAAGCGGAGGGAAGAGGAAGTGAGCCACGCGGC
CATGGTGATTCGGGCCCATGTCTTGGGCTTCTTAGCACGAAAACAATACAGAAAGGTCCTTTATTGTGTGGTGATAATACAGAAGAATTA
CAGAGCATTCCTTCTGAGGAGGAGATTTTTGCACCTGAAAAAGGCAGCCATAGTTTTCCAGAAGCAACTCAGAGGTCAGATTGCTCGGAG
AGTTTACAGACAATTGCTGGCAGAGAAAAGGGAGCAAGAAGAAAAGAAGAAACAGGAAGAGGAAGAAAAGAAGAAACGGGAGGAAGAAGA
AAGAGAAAGAGAGAGAGAGCGAAGAGAAGCCGAGCTCCGCGCCCAGCAGGAAGAAGAAACGAGGAAGCAGCAAGAACTCGAAGCCTTGCA
GAAGAGCCAGAAGGAAGCTGAACTGACCCGTGAACTGGAGAAACAGAAGGAAAATAAGCAGGTGGAAGAGATCCTCCGTCTGGAGAAAGA
AATCGAGGACCTGCAGCGCATGAAGGAGCAGCAGGAGCTGTCGCTGACCGAGGCTTCCCTGCAGAAGCTGCAGGAGCGGCGGGACCAGGA
GCTCCGCAGGCTGGAGGAGGAAGCGTGCAGGGCGGCCCAGGAGTTCCTCGAGTCCCTCAATTTCGACGAGATCGACGAGTGTGTCCGGAA
TATCGAGCGGTCCCTGTCGGTGGGAAGCGAATTTTCCAGCGAGCTGGCTGAGAGCGCATGCGAGGAGAAGCCCAACTTCAACTTCAGCCA
GCCCTACCCAGAGGAGGAGGTCGATGAGGGCTTCGAAGCCGACGACGACGCCTTCAAGGACTCCCCCAACCCCAGCGAGCACGGCCACTC
AGACCAGCGAACAAGTGGCATCCGGACCAGCGATGACTCTTCAGAGGAGGACCCATACATGAACGACACGGTGGTGCCCACCAGCCCCAG
TGCGGACAGCACGGTGCTGCTCGCCCCATCAGTGCAGGACTCCGGGAGCCTACACAACTCCTCCAGCGGCGAGTCCACCTACTGCATGCC
CCAGAACGCTGGGGACTTGCCCTCCCCAGACGGCGACTACGACTACGACCAGGATGACTATGAGGACGGTGCCATCACTTCCGGCAGCAG
CGTGACCTTCTCCAACTCCTACGGCAGCCAGTGGTCCCCCGACTACCGCTGCTCTGTGGGGACCTACAACAGCTCGGGTGCCTACCGGTT
CAGCTCTGAGGGGGCGCAGTCCTCGTTTGAAGATAGTGAAGAGGACTTTGATTCCAGGTTTGATACAGATGATGAGCTTTCATACCGGCG
TGACTCTGTGTACAGCTGTGTCACTCTGCCGTATTTCCACAGCTTTCTGTACATGAAAGGTGGCCTGATGAACTCTTGGAAACGCCGCTG
GTGCGTCCTCAAGGATGAAACCTTCTTGTGGTTCCGCTCCAAGCAGGAGGCCCTCAAGCAAGGCTGGCTCCACAAAAAAGGGGGGGGCTC
CTCCACGCTGTCCAGGAGAAATTGGAAGAAGCGCTGGTTTGTCCTCCGCCAGTCCAAGCTGATGTACTTTGAAAACGACAGCGAGGAGAA
GCTCAAGGGCACCGTAGAAGTGCGAACGGCAAAAGAGATCATAGATAACACCACCAAGGAGAATGGGATCGACATCATTATGGCCGATAG
GACTTTCCACCTGATTGCAGAGTCCCCAGAAGATGCCAGCCAGTGGTTCAGCGTGCTGAGTCAGGTCCACGCGTCCACGGACCAGGAGAT
CCAGGAGATGCATGATGAGCAGGCAAACCCACAGAATGCTGTGGGCACCTTGGATGTGGGGCTGATTGATTCTGTGTGTGCCTCTGACAG
CCCTGATAGACCCAACTCGTTTGTGATCATCACGGCCAACCGGGTGCTGCACTGCAACGCCGACACGCCGGAGGAGATGCACCACTGGAT
AACCCTGCTGCAGAGGTCCAAAGGGGACACCAGAGTGGAGGGCCAGGAATTCATCGTGAGAGGATGGTTGCACAAAGAGGTGAAGAACAG
TCCAAAGATGTCTTCACTGAAACTGAAGAAACGGTGGTTTGTACTCACCCACAATTCCCTGGATTACTACAAGAGTTCAGAGAAGAACGC
GCTCAAACTGGGGACCCTGGTCCTCAACAGCCTCTGCTCTGTCGTCCCCCCAGATGAGAAGATATTCAAAGAGACAGGCTACTGGAACGT
CACCGTGTACGGGCGCAAGCACTGTTACCGGCTCTACACCAAGCTGCTCAACGAGGCCACCCGGTGGTCCAGTGCCATTCAAAACGTGAC
TGACACCAAGGCCCCGATCGACACCCCCACCCAGCAGCTGATTCAAGATATCAAGGAGAACTGCCTGAACTCGGATGTGGTGGAACAGAT
TTACAAGCGGAACCCGATCCTTCGATACACCCATCACCCCTTGCACTCCCCGCTCCTGCCCCTTCCGTATGGGGACATAAATCTCAACTT
GCTCAAAGACAAAGGCTATACCACCCTTCAGGATGAGGCCATCAAGATATTCAATTCCCTGCAGCAACTGGAGTCCATGTCTGACCCAAT
TCCAATAATCCAGGGCATCCTACAGACAGGGCATGACCTGCGACCTCTGCGGGACGAGCTGTACTGCCAGCTTATCAAACAGACCAACAA
AGTGCCCCACCCCGGCAGTGTGGGCAACCTGTACAGCTGGCAGATCCTGACATGCCTGAGCTGCACCTTCCTGCCGAGTCGAGGGATTCT
CAAGTATCTCAAGTTCCATCTGAAAAGGATACGGGAACAGTTTCCAGGAAGCGAGATGGAAAAATACGCTCTCTTCACTTACGAATCTCT
TAAGAAAACCAAATGCCGAGAGTTTGTGCCTTCCCGAGATGAAATAGAAGCTCTGATCCACAGGCAGGAAATGACATCCACGGTCTATTG
CCATGGCGGCGGCTCCTGCAAGATCACCATCAACTCCCACACCACCGCTGGGGAGGTGGTGGAGAAGCTGATCCGAGGCCTGGCCATGGA
GGACAGCAGGAACATGTTTGCTTTGTTTGAATACAACGGCCACGTCGACAAAGCCATTGAAAGTCGAACCGTCGTAGCTGATGTCTTAGC
CAAGTTTGAAAAGCTGGCTGCCACATCCGAGGTTGGGGACCTGCCATGGAAATTCTACTTCAAACTTTACTGCTTCCTGGACACAGACAA
CGTGCCAAAAGACAGTGTGGAGTTTGCATTTATGTTTGAACAGGCCCACGAAGCGGTTATCCATGGCCACCATCCAGCCCCGGAAGAAAA
CCTCCAGGTTCTTGCTGCCCTGCGACTCCAGTATCTGCAGGGGGATTATACTCTGCACGCTGCCATCCCACCTCTCGAAGAGGTTTATTC
CCTGCAGAGACTCAAGGCCCGCATCAGCCAGTCAACCAAAACCTTCACCCCTTGTGAACGGCTGGAGAAGAGGCGGACGAGCTTCCTAGA
GGGGACCCTGAGGCGGAGCTTCCGGACAGGATCCGTGGTCCGGCAGAAGGTCGAGGAGGAGCAGATGCTGGACATGTGGATTAAGGAAGA
AGTCTCCTCTGCTCGAGCCAGTATCATTGACAAGTGGAGGAAATTTCAGGGAATGAACCAGGAACAGGCCATGGCCAAGTACATGGCCTT
GATCAAGGAGTGGCCTGGCTATGGCTCGACGCTGTTTGATGTGGAGTGCAAGGAAGGTGGCTTCCCTCAGGAACTCTGGTTGGGTGTCAG
CGCGGACGCCGTCTCCGTCTACAAGCGTGGAGAGGGAAGACCACTGGAAGTCTTCCAGTATGAACACATCCTCTCTTTTGGGGCACCCCT
GGCGAATACGTATAAGATCGTGGTCGATGAGAGGGAGCTGCTCTTTGAAACCAGTGAGGTGGTGGATGTGGCCAAGCTCATGAAAGCCTA
CATCAGCATGATCGTGAAGAAGCGCTACAGCACGACACGCTCCGCCAGCAGCCAGGGCAGCTCCAGGTGAAGGCGGGACAGAGCCCACCT
GTCTTTGCTACCTGAACGCACCACCCTCTGGCCTAGGCTGGCTCCAGTGTGCCATGCCCAGCCAAAACAAACACAGAGCTGCCCAGGCTT
TCTGGAAGCTTCTGGTCTGAGGGAGGTGTCTCCGAGGATCCTTTTGCCTGCCGCCTTCATTGATCCTGTATTAAGCTGTCAACTTTAACA
GTCTGCACAGTTTCCAAAGCTTTACTACTCTTAGAGGACACATGCCTTAAAAAAGGAGGGGAGGAACCACGCTGCCACCAAAGCAGCCGG
AAGTGCCTTAACTTGTGGAACCAACACTAATCGACCGTAACTGTGCTACTGAAGGGAACTGCCTTTCCCCCTTCTGGGGGAGACTTAACA
GAGCGTGGAAGGGGGGCATTCTCTGTCAATGATGCACTAACCTCCCAACCTGATTTCCCCGAATCTGAGGGAAGGTGAGGGAGTGGGAAG
GGGGATGGAGAGCTCGAGGGGACAGTGTGTTTGAGCTGGAGTGCTGCGGGCAGCCTTTCTCATGGAATGACATGAATCAACTTTTTTCTT
TGTTTCATCTTTTAAGTGTACGTGCTTGCCTGTTCGTGCATGTGTTCATAAACTCAACACTTTAATCATGGTTTCATGAGCATTAAAAAG
CAAAGGGAAAAAGGATGTGTAATGGTGTACACAGTCTGTATATTTTAATAATGCAGAGCTATAGTCTCAATTGTTACTTTATAAGGTGGT
TTTATTAACAAACCCAAATCCTGGATTTTCCTGTCTTTGCTGTATTTTGAAAAACACGTGTTGACTCCATTGTTTTACATGTAGCAAAGT
CTGCCATCTGTGTCTGCTGTATTATAAACAGATAAGCAGCCTACAAGATAACTGTATTTATAAACCACTCTTCAACAGCTGGCTCCAGTG
CTGGTTTTAGAACAAGAATGAAGTCATTTTGGAGTCTTTCATGTCTAAAAGATTTAAGTTAAAAACAAAGTGTTACTTGGAAGGTTAGCT
TCTATCATTCTGGATAGATTACAGATATAATAACCATGTTGACTATGGGGGAGAGACGCTGCATTCCAGAAACGTCTTAACACTTGAGTG
AATCTTCAAAGGACCCTGACATTAAATGCTGAGGCTTTAATACACACATATTTTATCCCAAGTTTATAATGGTGGTCTGAACAAGGCACC
TGTAAATAAATCAGCATTTATGACCAGAAGAAAAATAATCTGGTCTTGGACTTTTTATTTTTATATGGAAAAGTTTTAAGGACTTGGGCC
AACTAAGTCTACCCACACGAAAAAAGAAATTTGCCTTGTCCCTTTGTGTACAACCATGCAAAACTGTTTGTTGGCTCACAGAAGTTCTGA

>80690_80690_2_SERINC5-MYO10_SERINC5_chr5_79498705_ENST00000509193_MYO10_chr5_16704794_ENST00000513610_length(amino acids)=1404AA_BP=67
MAAAMSAQCCAGQLACCCGSAGCSLCCDCCPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMKEHVFLRESLEQKLEKRREEEVSH
AAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREE
EERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRD
QELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEHG
HSDQRTSGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTYCMPQNAGDLPSPDGDYDYDQDDYEDGAITSG
SSVTFSNSYGSQWSPDYRCSVGTYNSSGAYRFSSEGAQSSFEDSEEDFDSRFDTDDELSYRRDSVYSCVTLPYFHSFLYMKGGLMNSWKR
RWCVLKDETFLWFRSKQEALKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEKLKGTVEVRTAKEIIDNTTKENGIDIIMA
DRTFHLIAESPEDASQWFSVLSQVHASTDQEIQEMHDEQANPQNAVGTLDVGLIDSVCASDSPDRPNSFVIITANRVLHCNADTPEEMHH
WITLLQRSKGDTRVEGQEFIVRGWLHKEVKNSPKMSSLKLKKRWFVLTHNSLDYYKSSEKNALKLGTLVLNSLCSVVPPDEKIFKETGYW
NVTVYGRKHCYRLYTKLLNEATRWSSAIQNVTDTKAPIDTPTQQLIQDIKENCLNSDVVEQIYKRNPILRYTHHPLHSPLLPLPYGDINL
NLLKDKGYTTLQDEAIKIFNSLQQLESMSDPIPIIQGILQTGHDLRPLRDELYCQLIKQTNKVPHPGSVGNLYSWQILTCLSCTFLPSRG
ILKYLKFHLKRIREQFPGSEMEKYALFTYESLKKTKCREFVPSRDEIEALIHRQEMTSTVYCHGGGSCKITINSHTTAGEVVEKLIRGLA
MEDSRNMFALFEYNGHVDKAIESRTVVADVLAKFEKLAATSEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPE
ENLQVLAALRLQYLQGDYTLHAAIPPLEEVYSLQRLKARISQSTKTFTPCERLEKRRTSFLEGTLRRSFRTGSVVRQKVEEEQMLDMWIK
EEVSSARASIIDKWRKFQGMNQEQAMAKYMALIKEWPGYGSTLFDVECKEGGFPQELWLGVSADAVSVYKRGEGRPLEVFQYEHILSFGA

--------------------------------------------------------------
>80690_80690_3_SERINC5-MYO10_SERINC5_chr5_79498705_ENST00000512721_MYO10_chr5_16704794_ENST00000513610_length(transcript)=5766nt_BP=352nt
GTTTTTACCCAGGCCTCGGCGCCTAGGCGCTTCGCCGAGGCTGATCTTCGTTCAAGTGTGAGCTGCGGCTGAGCCCAGCGCTCGAGGCGC
GAGGCAGCCAGGAGGGCCCGTGCGGCGCGGGGAGCCAGCGAGCGCGCCTTCGGCATTGGCCGCCGCGATGTCAGCTCAGTGCTGTGCGGG
CCAGCTGGCCTGCTGCTGTGGGTCTGCAGGCTGCTCTCTCTGCTGTGATTGCTGCCCCAGGATTCGGCAGTCCCTCAGCACCCGCTTCAT
GTACGCCCTCTACTTCATTCTGGTCGTCGTCCTCTGCTGCATCATGATGTCAACAACCGTGGCTCACAAGATGAAAGAGCACGTCTTTCT
TCGAGAATCCTTGGAACAGAAACTGGAGAAGCGGAGGGAAGAGGAAGTGAGCCACGCGGCCATGGTGATTCGGGCCCATGTCTTGGGCTT
CTTAGCACGAAAACAATACAGAAAGGTCCTTTATTGTGTGGTGATAATACAGAAGAATTACAGAGCATTCCTTCTGAGGAGGAGATTTTT
GCACCTGAAAAAGGCAGCCATAGTTTTCCAGAAGCAACTCAGAGGTCAGATTGCTCGGAGAGTTTACAGACAATTGCTGGCAGAGAAAAG
GGAGCAAGAAGAAAAGAAGAAACAGGAAGAGGAAGAAAAGAAGAAACGGGAGGAAGAAGAAAGAGAAAGAGAGAGAGAGCGAAGAGAAGC
CGAGCTCCGCGCCCAGCAGGAAGAAGAAACGAGGAAGCAGCAAGAACTCGAAGCCTTGCAGAAGAGCCAGAAGGAAGCTGAACTGACCCG
TGAACTGGAGAAACAGAAGGAAAATAAGCAGGTGGAAGAGATCCTCCGTCTGGAGAAAGAAATCGAGGACCTGCAGCGCATGAAGGAGCA
GCAGGAGCTGTCGCTGACCGAGGCTTCCCTGCAGAAGCTGCAGGAGCGGCGGGACCAGGAGCTCCGCAGGCTGGAGGAGGAAGCGTGCAG
GGCGGCCCAGGAGTTCCTCGAGTCCCTCAATTTCGACGAGATCGACGAGTGTGTCCGGAATATCGAGCGGTCCCTGTCGGTGGGAAGCGA
ATTTTCCAGCGAGCTGGCTGAGAGCGCATGCGAGGAGAAGCCCAACTTCAACTTCAGCCAGCCCTACCCAGAGGAGGAGGTCGATGAGGG
CTTCGAAGCCGACGACGACGCCTTCAAGGACTCCCCCAACCCCAGCGAGCACGGCCACTCAGACCAGCGAACAAGTGGCATCCGGACCAG
CGATGACTCTTCAGAGGAGGACCCATACATGAACGACACGGTGGTGCCCACCAGCCCCAGTGCGGACAGCACGGTGCTGCTCGCCCCATC
AGTGCAGGACTCCGGGAGCCTACACAACTCCTCCAGCGGCGAGTCCACCTACTGCATGCCCCAGAACGCTGGGGACTTGCCCTCCCCAGA
CGGCGACTACGACTACGACCAGGATGACTATGAGGACGGTGCCATCACTTCCGGCAGCAGCGTGACCTTCTCCAACTCCTACGGCAGCCA
GTGGTCCCCCGACTACCGCTGCTCTGTGGGGACCTACAACAGCTCGGGTGCCTACCGGTTCAGCTCTGAGGGGGCGCAGTCCTCGTTTGA
AGATAGTGAAGAGGACTTTGATTCCAGGTTTGATACAGATGATGAGCTTTCATACCGGCGTGACTCTGTGTACAGCTGTGTCACTCTGCC
GTATTTCCACAGCTTTCTGTACATGAAAGGTGGCCTGATGAACTCTTGGAAACGCCGCTGGTGCGTCCTCAAGGATGAAACCTTCTTGTG
GTTCCGCTCCAAGCAGGAGGCCCTCAAGCAAGGCTGGCTCCACAAAAAAGGGGGGGGCTCCTCCACGCTGTCCAGGAGAAATTGGAAGAA
GCGCTGGTTTGTCCTCCGCCAGTCCAAGCTGATGTACTTTGAAAACGACAGCGAGGAGAAGCTCAAGGGCACCGTAGAAGTGCGAACGGC
AAAAGAGATCATAGATAACACCACCAAGGAGAATGGGATCGACATCATTATGGCCGATAGGACTTTCCACCTGATTGCAGAGTCCCCAGA
AGATGCCAGCCAGTGGTTCAGCGTGCTGAGTCAGGTCCACGCGTCCACGGACCAGGAGATCCAGGAGATGCATGATGAGCAGGCAAACCC
ACAGAATGCTGTGGGCACCTTGGATGTGGGGCTGATTGATTCTGTGTGTGCCTCTGACAGCCCTGATAGACCCAACTCGTTTGTGATCAT
CACGGCCAACCGGGTGCTGCACTGCAACGCCGACACGCCGGAGGAGATGCACCACTGGATAACCCTGCTGCAGAGGTCCAAAGGGGACAC
CAGAGTGGAGGGCCAGGAATTCATCGTGAGAGGATGGTTGCACAAAGAGGTGAAGAACAGTCCAAAGATGTCTTCACTGAAACTGAAGAA
ACGGTGGTTTGTACTCACCCACAATTCCCTGGATTACTACAAGAGTTCAGAGAAGAACGCGCTCAAACTGGGGACCCTGGTCCTCAACAG
CCTCTGCTCTGTCGTCCCCCCAGATGAGAAGATATTCAAAGAGACAGGCTACTGGAACGTCACCGTGTACGGGCGCAAGCACTGTTACCG
GCTCTACACCAAGCTGCTCAACGAGGCCACCCGGTGGTCCAGTGCCATTCAAAACGTGACTGACACCAAGGCCCCGATCGACACCCCCAC
CCAGCAGCTGATTCAAGATATCAAGGAGAACTGCCTGAACTCGGATGTGGTGGAACAGATTTACAAGCGGAACCCGATCCTTCGATACAC
CCATCACCCCTTGCACTCCCCGCTCCTGCCCCTTCCGTATGGGGACATAAATCTCAACTTGCTCAAAGACAAAGGCTATACCACCCTTCA
GGATGAGGCCATCAAGATATTCAATTCCCTGCAGCAACTGGAGTCCATGTCTGACCCAATTCCAATAATCCAGGGCATCCTACAGACAGG
GCATGACCTGCGACCTCTGCGGGACGAGCTGTACTGCCAGCTTATCAAACAGACCAACAAAGTGCCCCACCCCGGCAGTGTGGGCAACCT
GTACAGCTGGCAGATCCTGACATGCCTGAGCTGCACCTTCCTGCCGAGTCGAGGGATTCTCAAGTATCTCAAGTTCCATCTGAAAAGGAT
ACGGGAACAGTTTCCAGGAAGCGAGATGGAAAAATACGCTCTCTTCACTTACGAATCTCTTAAGAAAACCAAATGCCGAGAGTTTGTGCC
TTCCCGAGATGAAATAGAAGCTCTGATCCACAGGCAGGAAATGACATCCACGGTCTATTGCCATGGCGGCGGCTCCTGCAAGATCACCAT
CAACTCCCACACCACCGCTGGGGAGGTGGTGGAGAAGCTGATCCGAGGCCTGGCCATGGAGGACAGCAGGAACATGTTTGCTTTGTTTGA
ATACAACGGCCACGTCGACAAAGCCATTGAAAGTCGAACCGTCGTAGCTGATGTCTTAGCCAAGTTTGAAAAGCTGGCTGCCACATCCGA
GGTTGGGGACCTGCCATGGAAATTCTACTTCAAACTTTACTGCTTCCTGGACACAGACAACGTGCCAAAAGACAGTGTGGAGTTTGCATT
TATGTTTGAACAGGCCCACGAAGCGGTTATCCATGGCCACCATCCAGCCCCGGAAGAAAACCTCCAGGTTCTTGCTGCCCTGCGACTCCA
GTATCTGCAGGGGGATTATACTCTGCACGCTGCCATCCCACCTCTCGAAGAGGTTTATTCCCTGCAGAGACTCAAGGCCCGCATCAGCCA
GTCAACCAAAACCTTCACCCCTTGTGAACGGCTGGAGAAGAGGCGGACGAGCTTCCTAGAGGGGACCCTGAGGCGGAGCTTCCGGACAGG
ATCCGTGGTCCGGCAGAAGGTCGAGGAGGAGCAGATGCTGGACATGTGGATTAAGGAAGAAGTCTCCTCTGCTCGAGCCAGTATCATTGA
CAAGTGGAGGAAATTTCAGGGAATGAACCAGGAACAGGCCATGGCCAAGTACATGGCCTTGATCAAGGAGTGGCCTGGCTATGGCTCGAC
GCTGTTTGATGTGGAGTGCAAGGAAGGTGGCTTCCCTCAGGAACTCTGGTTGGGTGTCAGCGCGGACGCCGTCTCCGTCTACAAGCGTGG
AGAGGGAAGACCACTGGAAGTCTTCCAGTATGAACACATCCTCTCTTTTGGGGCACCCCTGGCGAATACGTATAAGATCGTGGTCGATGA
GAGGGAGCTGCTCTTTGAAACCAGTGAGGTGGTGGATGTGGCCAAGCTCATGAAAGCCTACATCAGCATGATCGTGAAGAAGCGCTACAG
CACGACACGCTCCGCCAGCAGCCAGGGCAGCTCCAGGTGAAGGCGGGACAGAGCCCACCTGTCTTTGCTACCTGAACGCACCACCCTCTG
GCCTAGGCTGGCTCCAGTGTGCCATGCCCAGCCAAAACAAACACAGAGCTGCCCAGGCTTTCTGGAAGCTTCTGGTCTGAGGGAGGTGTC
TCCGAGGATCCTTTTGCCTGCCGCCTTCATTGATCCTGTATTAAGCTGTCAACTTTAACAGTCTGCACAGTTTCCAAAGCTTTACTACTC
TTAGAGGACACATGCCTTAAAAAAGGAGGGGAGGAACCACGCTGCCACCAAAGCAGCCGGAAGTGCCTTAACTTGTGGAACCAACACTAA
TCGACCGTAACTGTGCTACTGAAGGGAACTGCCTTTCCCCCTTCTGGGGGAGACTTAACAGAGCGTGGAAGGGGGGCATTCTCTGTCAAT
GATGCACTAACCTCCCAACCTGATTTCCCCGAATCTGAGGGAAGGTGAGGGAGTGGGAAGGGGGATGGAGAGCTCGAGGGGACAGTGTGT
TTGAGCTGGAGTGCTGCGGGCAGCCTTTCTCATGGAATGACATGAATCAACTTTTTTCTTTGTTTCATCTTTTAAGTGTACGTGCTTGCC
TGTTCGTGCATGTGTTCATAAACTCAACACTTTAATCATGGTTTCATGAGCATTAAAAAGCAAAGGGAAAAAGGATGTGTAATGGTGTAC
ACAGTCTGTATATTTTAATAATGCAGAGCTATAGTCTCAATTGTTACTTTATAAGGTGGTTTTATTAACAAACCCAAATCCTGGATTTTC
CTGTCTTTGCTGTATTTTGAAAAACACGTGTTGACTCCATTGTTTTACATGTAGCAAAGTCTGCCATCTGTGTCTGCTGTATTATAAACA
GATAAGCAGCCTACAAGATAACTGTATTTATAAACCACTCTTCAACAGCTGGCTCCAGTGCTGGTTTTAGAACAAGAATGAAGTCATTTT
GGAGTCTTTCATGTCTAAAAGATTTAAGTTAAAAACAAAGTGTTACTTGGAAGGTTAGCTTCTATCATTCTGGATAGATTACAGATATAA
TAACCATGTTGACTATGGGGGAGAGACGCTGCATTCCAGAAACGTCTTAACACTTGAGTGAATCTTCAAAGGACCCTGACATTAAATGCT
GAGGCTTTAATACACACATATTTTATCCCAAGTTTATAATGGTGGTCTGAACAAGGCACCTGTAAATAAATCAGCATTTATGACCAGAAG
AAAAATAATCTGGTCTTGGACTTTTTATTTTTATATGGAAAAGTTTTAAGGACTTGGGCCAACTAAGTCTACCCACACGAAAAAAGAAAT
TTGCCTTGTCCCTTTGTGTACAACCATGCAAAACTGTTTGTTGGCTCACAGAAGTTCTGACAATAAAAGATACTAGCTAACACGCTGTGT

>80690_80690_3_SERINC5-MYO10_SERINC5_chr5_79498705_ENST00000512721_MYO10_chr5_16704794_ENST00000513610_length(amino acids)=1404AA_BP=67
MAAAMSAQCCAGQLACCCGSAGCSLCCDCCPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMKEHVFLRESLEQKLEKRREEEVSH
AAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREE
EERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRD
QELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEHG
HSDQRTSGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTYCMPQNAGDLPSPDGDYDYDQDDYEDGAITSG
SSVTFSNSYGSQWSPDYRCSVGTYNSSGAYRFSSEGAQSSFEDSEEDFDSRFDTDDELSYRRDSVYSCVTLPYFHSFLYMKGGLMNSWKR
RWCVLKDETFLWFRSKQEALKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEKLKGTVEVRTAKEIIDNTTKENGIDIIMA
DRTFHLIAESPEDASQWFSVLSQVHASTDQEIQEMHDEQANPQNAVGTLDVGLIDSVCASDSPDRPNSFVIITANRVLHCNADTPEEMHH
WITLLQRSKGDTRVEGQEFIVRGWLHKEVKNSPKMSSLKLKKRWFVLTHNSLDYYKSSEKNALKLGTLVLNSLCSVVPPDEKIFKETGYW
NVTVYGRKHCYRLYTKLLNEATRWSSAIQNVTDTKAPIDTPTQQLIQDIKENCLNSDVVEQIYKRNPILRYTHHPLHSPLLPLPYGDINL
NLLKDKGYTTLQDEAIKIFNSLQQLESMSDPIPIIQGILQTGHDLRPLRDELYCQLIKQTNKVPHPGSVGNLYSWQILTCLSCTFLPSRG
ILKYLKFHLKRIREQFPGSEMEKYALFTYESLKKTKCREFVPSRDEIEALIHRQEMTSTVYCHGGGSCKITINSHTTAGEVVEKLIRGLA
MEDSRNMFALFEYNGHVDKAIESRTVVADVLAKFEKLAATSEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPE
ENLQVLAALRLQYLQGDYTLHAAIPPLEEVYSLQRLKARISQSTKTFTPCERLEKRRTSFLEGTLRRSFRTGSVVRQKVEEEQMLDMWIK
EEVSSARASIIDKWRKFQGMNQEQAMAKYMALIKEWPGYGSTLFDVECKEGGFPQELWLGVSADAVSVYKRGEGRPLEVFQYEHILSFGA

--------------------------------------------------------------
>80690_80690_4_SERINC5-MYO10_SERINC5_chr5_79498705_ENST00000512972_MYO10_chr5_16704794_ENST00000513610_length(transcript)=5706nt_BP=292nt
AGCTGCGGCTGAGCCCAGCGCTCGAGGCGCGAGGCAGCCAGGAGGGCCCGTGCGGCGCGGGGAGCCAGCGAGCGCGCCTTCGGCATTGGC
CGCCGCGATGTCAGCTCAGTGCTGTGCGGGCCAGCTGGCCTGCTGCTGTGGGTCTGCAGGCTGCTCTCTCTGCTGTGATTGCTGCCCCAG
GATTCGGCAGTCCCTCAGCACCCGCTTCATGTACGCCCTCTACTTCATTCTGGTCGTCGTCCTCTGCTGCATCATGATGTCAACAACCGT
GGCTCACAAGATGAAAGAGCACGTCTTTCTTCGAGAATCCTTGGAACAGAAACTGGAGAAGCGGAGGGAAGAGGAAGTGAGCCACGCGGC
CATGGTGATTCGGGCCCATGTCTTGGGCTTCTTAGCACGAAAACAATACAGAAAGGTCCTTTATTGTGTGGTGATAATACAGAAGAATTA
CAGAGCATTCCTTCTGAGGAGGAGATTTTTGCACCTGAAAAAGGCAGCCATAGTTTTCCAGAAGCAACTCAGAGGTCAGATTGCTCGGAG
AGTTTACAGACAATTGCTGGCAGAGAAAAGGGAGCAAGAAGAAAAGAAGAAACAGGAAGAGGAAGAAAAGAAGAAACGGGAGGAAGAAGA
AAGAGAAAGAGAGAGAGAGCGAAGAGAAGCCGAGCTCCGCGCCCAGCAGGAAGAAGAAACGAGGAAGCAGCAAGAACTCGAAGCCTTGCA
GAAGAGCCAGAAGGAAGCTGAACTGACCCGTGAACTGGAGAAACAGAAGGAAAATAAGCAGGTGGAAGAGATCCTCCGTCTGGAGAAAGA
AATCGAGGACCTGCAGCGCATGAAGGAGCAGCAGGAGCTGTCGCTGACCGAGGCTTCCCTGCAGAAGCTGCAGGAGCGGCGGGACCAGGA
GCTCCGCAGGCTGGAGGAGGAAGCGTGCAGGGCGGCCCAGGAGTTCCTCGAGTCCCTCAATTTCGACGAGATCGACGAGTGTGTCCGGAA
TATCGAGCGGTCCCTGTCGGTGGGAAGCGAATTTTCCAGCGAGCTGGCTGAGAGCGCATGCGAGGAGAAGCCCAACTTCAACTTCAGCCA
GCCCTACCCAGAGGAGGAGGTCGATGAGGGCTTCGAAGCCGACGACGACGCCTTCAAGGACTCCCCCAACCCCAGCGAGCACGGCCACTC
AGACCAGCGAACAAGTGGCATCCGGACCAGCGATGACTCTTCAGAGGAGGACCCATACATGAACGACACGGTGGTGCCCACCAGCCCCAG
TGCGGACAGCACGGTGCTGCTCGCCCCATCAGTGCAGGACTCCGGGAGCCTACACAACTCCTCCAGCGGCGAGTCCACCTACTGCATGCC
CCAGAACGCTGGGGACTTGCCCTCCCCAGACGGCGACTACGACTACGACCAGGATGACTATGAGGACGGTGCCATCACTTCCGGCAGCAG
CGTGACCTTCTCCAACTCCTACGGCAGCCAGTGGTCCCCCGACTACCGCTGCTCTGTGGGGACCTACAACAGCTCGGGTGCCTACCGGTT
CAGCTCTGAGGGGGCGCAGTCCTCGTTTGAAGATAGTGAAGAGGACTTTGATTCCAGGTTTGATACAGATGATGAGCTTTCATACCGGCG
TGACTCTGTGTACAGCTGTGTCACTCTGCCGTATTTCCACAGCTTTCTGTACATGAAAGGTGGCCTGATGAACTCTTGGAAACGCCGCTG
GTGCGTCCTCAAGGATGAAACCTTCTTGTGGTTCCGCTCCAAGCAGGAGGCCCTCAAGCAAGGCTGGCTCCACAAAAAAGGGGGGGGCTC
CTCCACGCTGTCCAGGAGAAATTGGAAGAAGCGCTGGTTTGTCCTCCGCCAGTCCAAGCTGATGTACTTTGAAAACGACAGCGAGGAGAA
GCTCAAGGGCACCGTAGAAGTGCGAACGGCAAAAGAGATCATAGATAACACCACCAAGGAGAATGGGATCGACATCATTATGGCCGATAG
GACTTTCCACCTGATTGCAGAGTCCCCAGAAGATGCCAGCCAGTGGTTCAGCGTGCTGAGTCAGGTCCACGCGTCCACGGACCAGGAGAT
CCAGGAGATGCATGATGAGCAGGCAAACCCACAGAATGCTGTGGGCACCTTGGATGTGGGGCTGATTGATTCTGTGTGTGCCTCTGACAG
CCCTGATAGACCCAACTCGTTTGTGATCATCACGGCCAACCGGGTGCTGCACTGCAACGCCGACACGCCGGAGGAGATGCACCACTGGAT
AACCCTGCTGCAGAGGTCCAAAGGGGACACCAGAGTGGAGGGCCAGGAATTCATCGTGAGAGGATGGTTGCACAAAGAGGTGAAGAACAG
TCCAAAGATGTCTTCACTGAAACTGAAGAAACGGTGGTTTGTACTCACCCACAATTCCCTGGATTACTACAAGAGTTCAGAGAAGAACGC
GCTCAAACTGGGGACCCTGGTCCTCAACAGCCTCTGCTCTGTCGTCCCCCCAGATGAGAAGATATTCAAAGAGACAGGCTACTGGAACGT
CACCGTGTACGGGCGCAAGCACTGTTACCGGCTCTACACCAAGCTGCTCAACGAGGCCACCCGGTGGTCCAGTGCCATTCAAAACGTGAC
TGACACCAAGGCCCCGATCGACACCCCCACCCAGCAGCTGATTCAAGATATCAAGGAGAACTGCCTGAACTCGGATGTGGTGGAACAGAT
TTACAAGCGGAACCCGATCCTTCGATACACCCATCACCCCTTGCACTCCCCGCTCCTGCCCCTTCCGTATGGGGACATAAATCTCAACTT
GCTCAAAGACAAAGGCTATACCACCCTTCAGGATGAGGCCATCAAGATATTCAATTCCCTGCAGCAACTGGAGTCCATGTCTGACCCAAT
TCCAATAATCCAGGGCATCCTACAGACAGGGCATGACCTGCGACCTCTGCGGGACGAGCTGTACTGCCAGCTTATCAAACAGACCAACAA
AGTGCCCCACCCCGGCAGTGTGGGCAACCTGTACAGCTGGCAGATCCTGACATGCCTGAGCTGCACCTTCCTGCCGAGTCGAGGGATTCT
CAAGTATCTCAAGTTCCATCTGAAAAGGATACGGGAACAGTTTCCAGGAAGCGAGATGGAAAAATACGCTCTCTTCACTTACGAATCTCT
TAAGAAAACCAAATGCCGAGAGTTTGTGCCTTCCCGAGATGAAATAGAAGCTCTGATCCACAGGCAGGAAATGACATCCACGGTCTATTG
CCATGGCGGCGGCTCCTGCAAGATCACCATCAACTCCCACACCACCGCTGGGGAGGTGGTGGAGAAGCTGATCCGAGGCCTGGCCATGGA
GGACAGCAGGAACATGTTTGCTTTGTTTGAATACAACGGCCACGTCGACAAAGCCATTGAAAGTCGAACCGTCGTAGCTGATGTCTTAGC
CAAGTTTGAAAAGCTGGCTGCCACATCCGAGGTTGGGGACCTGCCATGGAAATTCTACTTCAAACTTTACTGCTTCCTGGACACAGACAA
CGTGCCAAAAGACAGTGTGGAGTTTGCATTTATGTTTGAACAGGCCCACGAAGCGGTTATCCATGGCCACCATCCAGCCCCGGAAGAAAA
CCTCCAGGTTCTTGCTGCCCTGCGACTCCAGTATCTGCAGGGGGATTATACTCTGCACGCTGCCATCCCACCTCTCGAAGAGGTTTATTC
CCTGCAGAGACTCAAGGCCCGCATCAGCCAGTCAACCAAAACCTTCACCCCTTGTGAACGGCTGGAGAAGAGGCGGACGAGCTTCCTAGA
GGGGACCCTGAGGCGGAGCTTCCGGACAGGATCCGTGGTCCGGCAGAAGGTCGAGGAGGAGCAGATGCTGGACATGTGGATTAAGGAAGA
AGTCTCCTCTGCTCGAGCCAGTATCATTGACAAGTGGAGGAAATTTCAGGGAATGAACCAGGAACAGGCCATGGCCAAGTACATGGCCTT
GATCAAGGAGTGGCCTGGCTATGGCTCGACGCTGTTTGATGTGGAGTGCAAGGAAGGTGGCTTCCCTCAGGAACTCTGGTTGGGTGTCAG
CGCGGACGCCGTCTCCGTCTACAAGCGTGGAGAGGGAAGACCACTGGAAGTCTTCCAGTATGAACACATCCTCTCTTTTGGGGCACCCCT
GGCGAATACGTATAAGATCGTGGTCGATGAGAGGGAGCTGCTCTTTGAAACCAGTGAGGTGGTGGATGTGGCCAAGCTCATGAAAGCCTA
CATCAGCATGATCGTGAAGAAGCGCTACAGCACGACACGCTCCGCCAGCAGCCAGGGCAGCTCCAGGTGAAGGCGGGACAGAGCCCACCT
GTCTTTGCTACCTGAACGCACCACCCTCTGGCCTAGGCTGGCTCCAGTGTGCCATGCCCAGCCAAAACAAACACAGAGCTGCCCAGGCTT
TCTGGAAGCTTCTGGTCTGAGGGAGGTGTCTCCGAGGATCCTTTTGCCTGCCGCCTTCATTGATCCTGTATTAAGCTGTCAACTTTAACA
GTCTGCACAGTTTCCAAAGCTTTACTACTCTTAGAGGACACATGCCTTAAAAAAGGAGGGGAGGAACCACGCTGCCACCAAAGCAGCCGG
AAGTGCCTTAACTTGTGGAACCAACACTAATCGACCGTAACTGTGCTACTGAAGGGAACTGCCTTTCCCCCTTCTGGGGGAGACTTAACA
GAGCGTGGAAGGGGGGCATTCTCTGTCAATGATGCACTAACCTCCCAACCTGATTTCCCCGAATCTGAGGGAAGGTGAGGGAGTGGGAAG
GGGGATGGAGAGCTCGAGGGGACAGTGTGTTTGAGCTGGAGTGCTGCGGGCAGCCTTTCTCATGGAATGACATGAATCAACTTTTTTCTT
TGTTTCATCTTTTAAGTGTACGTGCTTGCCTGTTCGTGCATGTGTTCATAAACTCAACACTTTAATCATGGTTTCATGAGCATTAAAAAG
CAAAGGGAAAAAGGATGTGTAATGGTGTACACAGTCTGTATATTTTAATAATGCAGAGCTATAGTCTCAATTGTTACTTTATAAGGTGGT
TTTATTAACAAACCCAAATCCTGGATTTTCCTGTCTTTGCTGTATTTTGAAAAACACGTGTTGACTCCATTGTTTTACATGTAGCAAAGT
CTGCCATCTGTGTCTGCTGTATTATAAACAGATAAGCAGCCTACAAGATAACTGTATTTATAAACCACTCTTCAACAGCTGGCTCCAGTG
CTGGTTTTAGAACAAGAATGAAGTCATTTTGGAGTCTTTCATGTCTAAAAGATTTAAGTTAAAAACAAAGTGTTACTTGGAAGGTTAGCT
TCTATCATTCTGGATAGATTACAGATATAATAACCATGTTGACTATGGGGGAGAGACGCTGCATTCCAGAAACGTCTTAACACTTGAGTG
AATCTTCAAAGGACCCTGACATTAAATGCTGAGGCTTTAATACACACATATTTTATCCCAAGTTTATAATGGTGGTCTGAACAAGGCACC
TGTAAATAAATCAGCATTTATGACCAGAAGAAAAATAATCTGGTCTTGGACTTTTTATTTTTATATGGAAAAGTTTTAAGGACTTGGGCC
AACTAAGTCTACCCACACGAAAAAAGAAATTTGCCTTGTCCCTTTGTGTACAACCATGCAAAACTGTTTGTTGGCTCACAGAAGTTCTGA

>80690_80690_4_SERINC5-MYO10_SERINC5_chr5_79498705_ENST00000512972_MYO10_chr5_16704794_ENST00000513610_length(amino acids)=1404AA_BP=67
MAAAMSAQCCAGQLACCCGSAGCSLCCDCCPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMKEHVFLRESLEQKLEKRREEEVSH
AAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREE
EERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRD
QELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEHG
HSDQRTSGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTYCMPQNAGDLPSPDGDYDYDQDDYEDGAITSG
SSVTFSNSYGSQWSPDYRCSVGTYNSSGAYRFSSEGAQSSFEDSEEDFDSRFDTDDELSYRRDSVYSCVTLPYFHSFLYMKGGLMNSWKR
RWCVLKDETFLWFRSKQEALKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEKLKGTVEVRTAKEIIDNTTKENGIDIIMA
DRTFHLIAESPEDASQWFSVLSQVHASTDQEIQEMHDEQANPQNAVGTLDVGLIDSVCASDSPDRPNSFVIITANRVLHCNADTPEEMHH
WITLLQRSKGDTRVEGQEFIVRGWLHKEVKNSPKMSSLKLKKRWFVLTHNSLDYYKSSEKNALKLGTLVLNSLCSVVPPDEKIFKETGYW
NVTVYGRKHCYRLYTKLLNEATRWSSAIQNVTDTKAPIDTPTQQLIQDIKENCLNSDVVEQIYKRNPILRYTHHPLHSPLLPLPYGDINL
NLLKDKGYTTLQDEAIKIFNSLQQLESMSDPIPIIQGILQTGHDLRPLRDELYCQLIKQTNKVPHPGSVGNLYSWQILTCLSCTFLPSRG
ILKYLKFHLKRIREQFPGSEMEKYALFTYESLKKTKCREFVPSRDEIEALIHRQEMTSTVYCHGGGSCKITINSHTTAGEVVEKLIRGLA
MEDSRNMFALFEYNGHVDKAIESRTVVADVLAKFEKLAATSEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPE
ENLQVLAALRLQYLQGDYTLHAAIPPLEEVYSLQRLKARISQSTKTFTPCERLEKRRTSFLEGTLRRSFRTGSVVRQKVEEEQMLDMWIK
EEVSSARASIIDKWRKFQGMNQEQAMAKYMALIKEWPGYGSTLFDVECKEGGFPQELWLGVSADAVSVYKRGEGRPLEVFQYEHILSFGA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SERINC5-MYO10


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SERINC5-MYO10


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SERINC5-MYO10


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource