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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SETD2-NISCH (FusionGDB2 ID:80877) |
Fusion Gene Summary for SETD2-NISCH |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SETD2-NISCH | Fusion gene ID: 80877 | Hgene | Tgene | Gene symbol | SETD2 | NISCH | Gene ID | 29072 | 11188 |
| Gene name | SET domain containing 2, histone lysine methyltransferase | nischarin | |
| Synonyms | HBP231|HIF-1|HIP-1|HSPC069|HYPB|KMT3A|LLS|SET2|p231HBP | I-1|IR1|IRAS|hIRAS | |
| Cytomap | 3p21.31 | 3p21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | histone-lysine N-methyltransferase SETD2SET domain containing 2huntingtin interacting protein 1huntingtin yeast partner Bhuntingtin-interacting protein Blysine N-methyltransferase 3Aprotein-lysine N-methyltransferase SETD2 | nischarinI-1 receptor candidate proteinI1R candidate proteinimidazoline receptor 1imidazoline receptor antisera selected | |
| Modification date | 20200315 | 20200320 | |
| UniProtAcc | . | Q9Y2I1 | |
| Ensembl transtripts involved in fusion gene | ENST00000409792, ENST00000492397, | ENST00000464280, ENST00000345716, ENST00000420808, ENST00000479054, ENST00000488380, | |
| Fusion gene scores | * DoF score | 27 X 19 X 16=8208 | 6 X 5 X 4=120 |
| # samples | 41 | 6 | |
| ** MAII score | log2(41/8208*10)=-4.32333491610161 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SETD2 [Title/Abstract] AND NISCH [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SETD2(47125210)-NISCH(52504875), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SETD2 | GO:0010569 | regulation of double-strand break repair via homologous recombination | 24843002 |
| Hgene | SETD2 | GO:0018023 | peptidyl-lysine trimethylation | 27518565 |
| Hgene | SETD2 | GO:0018026 | peptidyl-lysine monomethylation | 28753426 |
| Hgene | SETD2 | GO:0032465 | regulation of cytokinesis | 27518565 |
| Hgene | SETD2 | GO:0032727 | positive regulation of interferon-alpha production | 28753426 |
| Hgene | SETD2 | GO:0034340 | response to type I interferon | 28753426 |
| Hgene | SETD2 | GO:0051607 | defense response to virus | 28753426 |
| Hgene | SETD2 | GO:0097198 | histone H3-K36 trimethylation | 23043551|24843002|26002201|27474439|28753426 |
| Hgene | SETD2 | GO:0097676 | histone H3-K36 dimethylation | 26002201 |
| Hgene | SETD2 | GO:1902850 | microtubule cytoskeleton organization involved in mitosis | 27518565 |
| Hgene | SETD2 | GO:1905634 | regulation of protein localization to chromatin | 24843002 |
| Fusion gene breakpoints across SETD2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across NISCH (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | MESO | TCGA-ZN-A9VO-01A | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + |
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Fusion Gene ORF analysis for SETD2-NISCH |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000409792 | ENST00000464280 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + |
| 5UTR-3CDS | ENST00000492397 | ENST00000345716 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + |
| 5UTR-3CDS | ENST00000492397 | ENST00000420808 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + |
| 5UTR-3CDS | ENST00000492397 | ENST00000479054 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + |
| 5UTR-3CDS | ENST00000492397 | ENST00000488380 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + |
| 5UTR-intron | ENST00000492397 | ENST00000464280 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + |
| In-frame | ENST00000409792 | ENST00000345716 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + |
| In-frame | ENST00000409792 | ENST00000420808 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + |
| In-frame | ENST00000409792 | ENST00000479054 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + |
| In-frame | ENST00000409792 | ENST00000488380 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000409792 | SETD2 | chr3 | 47125210 | - | ENST00000479054 | NISCH | chr3 | 52504875 | + | 10844 | 6103 | 1 | 10257 | 3418 |
| ENST00000409792 | SETD2 | chr3 | 47125210 | - | ENST00000345716 | NISCH | chr3 | 52504875 | + | 10847 | 6103 | 1 | 10257 | 3418 |
| ENST00000409792 | SETD2 | chr3 | 47125210 | - | ENST00000488380 | NISCH | chr3 | 52504875 | + | 8886 | 6103 | 1 | 7494 | 2497 |
| ENST00000409792 | SETD2 | chr3 | 47125210 | - | ENST00000420808 | NISCH | chr3 | 52504875 | + | 8307 | 6103 | 1 | 7290 | 2429 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000409792 | ENST00000479054 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + | 0.000898658 | 0.9991014 |
| ENST00000409792 | ENST00000345716 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + | 0.000901776 | 0.9990983 |
| ENST00000409792 | ENST00000488380 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + | 0.000463816 | 0.99953616 |
| ENST00000409792 | ENST00000420808 | SETD2 | chr3 | 47125210 | - | NISCH | chr3 | 52504875 | + | 0.000557386 | 0.99944264 |
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Fusion Genomic Features for SETD2-NISCH |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| SETD2 | chr3 | 47125209 | - | NISCH | chr3 | 52504874 | + | 0.000280677 | 0.9997193 |
| SETD2 | chr3 | 47125209 | - | NISCH | chr3 | 52504874 | + | 0.000280677 | 0.9997193 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SETD2-NISCH |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:47125210/chr3:52504875) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | NISCH |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Acts either as the functional imidazoline-1 receptor (I1R) candidate or as a membrane-associated mediator of the I1R signaling. Binds numerous imidazoline ligands that induces initiation of cell-signaling cascades triggering to cell survival, growth and migration. Its activation by the agonist rilmenidine induces an increase in phosphorylation of mitogen-activated protein kinases MAPK1 and MAPK3 in rostral ventrolateral medulla (RVLM) neurons that exhibited rilmenidine-evoked hypotension (By similarity). Blocking its activation with efaroxan abolished rilmenidine-induced mitogen-activated protein kinase phosphorylation in RVLM neurons (By similarity). Acts as a modulator of Rac-regulated signal transduction pathways (By similarity). Suppresses Rac1-stimulated cell migration by interacting with PAK1 and inhibiting its kinase activity (By similarity). Also blocks Pak-independent Rac signaling by interacting with RAC1 and inhibiting Rac1-stimulated NF-kB response element and cyclin D1 promoter activation (By similarity). Inhibits also LIMK1 kinase activity by reducing LIMK1 'Tyr-508' phosphorylation (By similarity). Inhibits Rac-induced cell migration and invasion in breast and colon epithelial cells (By similarity). Inhibits lamellipodia formation, when overexpressed (By similarity). Plays a role in protection against apoptosis. Involved in association with IRS4 in the enhancement of insulin activation of MAPK1 and MAPK3. When overexpressed, induces a redistribution of cell surface ITGA5 integrin to intracellular endosomal structures. {ECO:0000250, ECO:0000269|PubMed:10882231, ECO:0000269|PubMed:12868002, ECO:0000269|PubMed:15028619, ECO:0000269|PubMed:15028621, ECO:0000269|PubMed:15475348}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 166_247 | 2020 | 2565.0 | Compositional bias | Note=Pro-rich |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 385_456 | 2020 | 2565.0 | Compositional bias | Note=Arg-rich |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 1494_1548 | 2020 | 2565.0 | Domain | AWS |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 1550_1667 | 2020 | 2565.0 | Domain | SET |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 1674_1690 | 2020 | 2565.0 | Domain | Post-SET |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 1560_1562 | 2020 | 2565.0 | Region | S-adenosyl-L-methionine binding |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 1603_1605 | 2020 | 2565.0 | Region | S-adenosyl-L-methionine binding |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 1628_1629 | 2020 | 2565.0 | Region | S-adenosyl-L-methionine binding |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 634_695 | 120 | 1505.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 634_695 | 120 | 516.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 634_695 | 120 | 1505.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 1048_1104 | 120 | 1505.0 | Compositional bias | Note=Ala/Pro-rich | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 629_691 | 120 | 1505.0 | Compositional bias | Note=Glu-rich | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 1048_1104 | 120 | 516.0 | Compositional bias | Note=Ala/Pro-rich | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 629_691 | 120 | 516.0 | Compositional bias | Note=Glu-rich | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 1048_1104 | 120 | 1505.0 | Compositional bias | Note=Ala/Pro-rich | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 629_691 | 120 | 1505.0 | Compositional bias | Note=Glu-rich | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 120_695 | 120 | 1505.0 | Region | Note=Necessary for homooligomerization and targeting to endosomes | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 120_695 | 120 | 516.0 | Region | Note=Necessary for homooligomerization and targeting to endosomes | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 120_695 | 120 | 1505.0 | Region | Note=Necessary for homooligomerization and targeting to endosomes | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 288_309 | 120 | 1505.0 | Repeat | Note=LRR 1 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 311_332 | 120 | 1505.0 | Repeat | Note=LRR 2 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 333_354 | 120 | 1505.0 | Repeat | Note=LRR 3 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 356_377 | 120 | 1505.0 | Repeat | Note=LRR 4 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 378_399 | 120 | 1505.0 | Repeat | Note=LRR 5 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 403_424 | 120 | 1505.0 | Repeat | Note=LRR 6 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 288_309 | 120 | 516.0 | Repeat | Note=LRR 1 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 311_332 | 120 | 516.0 | Repeat | Note=LRR 2 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 333_354 | 120 | 516.0 | Repeat | Note=LRR 3 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 356_377 | 120 | 516.0 | Repeat | Note=LRR 4 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 378_399 | 120 | 516.0 | Repeat | Note=LRR 5 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 403_424 | 120 | 516.0 | Repeat | Note=LRR 6 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 288_309 | 120 | 1505.0 | Repeat | Note=LRR 1 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 311_332 | 120 | 1505.0 | Repeat | Note=LRR 2 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 333_354 | 120 | 1505.0 | Repeat | Note=LRR 3 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 356_377 | 120 | 1505.0 | Repeat | Note=LRR 4 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 378_399 | 120 | 1505.0 | Repeat | Note=LRR 5 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 403_424 | 120 | 1505.0 | Repeat | Note=LRR 6 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 2117_2146 | 2020 | 2565.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 2149_2232 | 2020 | 2565.0 | Compositional bias | Note=Pro-rich |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 2266_2365 | 2020 | 2565.0 | Compositional bias | Note=Gln-rich |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 2389_2422 | 2020 | 2565.0 | Domain | WW |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 2137_2366 | 2020 | 2565.0 | Region | Low charge region |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 11_121 | 120 | 1505.0 | Domain | PX | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 11_121 | 120 | 516.0 | Domain | PX | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 11_121 | 120 | 1505.0 | Domain | PX | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 2_133 | 120 | 1505.0 | Region | Note=Necessary for binding to phosphoinositide-3-P%3B not sufficient for targeting to endosomes | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 2_133 | 120 | 516.0 | Region | Note=Necessary for binding to phosphoinositide-3-P%3B not sufficient for targeting to endosomes | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 2_133 | 120 | 1505.0 | Region | Note=Necessary for binding to phosphoinositide-3-P%3B not sufficient for targeting to endosomes |
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Fusion Gene Sequence for SETD2-NISCH |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >80877_80877_1_SETD2-NISCH_SETD2_chr3_47125210_ENST00000409792_NISCH_chr3_52504875_ENST00000345716_length(transcript)=10847nt_BP=6103nt GCTGCGGGGAGGGGGCTCGCGTCGCCGTCTCCAGCCGCTCCCGATGAAGCAGCTGCAGCCGCAGCCGCCTCCGAAGATGGGGGATTTCTA CGACCCGGAGCACCCGACCCCTGAAGAAGAAGAAAATGAGGCAAAGATTGAAAATGTGCAGAAAACAGGTTTCATCAAAGGACCAATGTT CAAAGGTGTTGCTTCTAGTCGATTTTTGCCCAAAGGCACCAAAACAAAAGTTAATTTGGAAGAACAGGGACGACAGAAGGTGTCATTCAG CTTCAGCCTTACAAAGAAAACTTTGCAGAATAGGTTTCTCACTGCACTTGGCAATGAAAAGCAAAGTGATACTCCAAACCCTCCAGCTGT ACCTCTTCAGGTAGACTCGACTCCTAAAATGAAAATGGAAATTGGTGATACCTTATCTACTGCAGAAGAATCTTCCCCACCAAAGTCAAG GGTGGAATTGGGCAAAATTCATTTTAAGAAACATCTGCTTCATGTAACATCCAGGCCACTGCTGGCTACTACCACAGCAGTAGCATCTCC ACCTACTCATGCAGCACCATTACCAGCAGTGATAGCAGAATCAACAACTGTAGACTCACCGCCCTCATCTCCGCCTCCACCGCCTCCACC TGCCCAAGCCACAACACTCTCATCACCAGCACCAGTAACAGAGCCAGTGGCCTTGCCACATACACCAATAACAGTTCTAATGGCAGCACC AGTACCCTTACCAGTAGATGTAGCAGTTAGATCTCTGAAAGAACCACCAATTATAATTGTACCAGAATCTTTAGAAGCAGATACTAAGCA GGACACTATATCTAATAGTTTAGAAGAACACGTAACTCAAATATTGAATGAGCAAGCAGATATTTCCTCAAAAAAAGAAGATTCCCATAT TGGGAAGGATGAAGAAATTCCAGATAGTTCTAAGATTAGTCTGAGCTGTAAAAAAACAGGTTCTAAGAAGAAATCCTCACAATCTGAAGG CATCTTTCTTGGTTCAGAATCTGATGAAGATTCTGTACGGACTTCTTCAAGTCAAAGATCACATGATTTAAAATTTTCAGCAAGCATTGA AAAGGAAAGAGATTTTAAAAAGAGCTCAGCACCTTTAAAAAGTGAGGATCTAGGGAAACCTTCACGATCTAAAACAGACAGAGATGATAA ATATTTTAGCTATTCAAAACTTGAAAGAGATACTCGGTATGTATCTTCCCGATGTAGATCAGAAAGAGAGCGACGGCGGAGCAGATCTCA CTCTAGGTCTGAGAGAGGCTCTAGAACTAATTTATCCTATTCCAGGTCAGAACGATCTCATTATTATGACTCTGATCGTCGCTACCATAG GAGCTCCCCTTATCGAGAGAGGACGCGCTATTCTCGGCCATACACAGATAACAGAGCACGAGAGAGTTCTGACTCAGAAGAAGAGTATAA GAAGACATACTCAAGGCGTACCTCATCTCATTCCTCTTCTTACAGAGACCTAAGGACATCATCCTATTCTAAATCTGATCGGGACTGTAA AACTGAGACCTCTTACTTAGAGATGGAAAGAAGAGGCAAGTATTCTTCAAAACTAGAAAGAGAATCTAAAAGGACTTCAGAAAATGAAGC AATTAAAAGATGTTGTTCTCCCCCTAATGAACTGGGATTCCGACGAGGGTCATCATATTCTAAGCATGACAGTAGTGCTTCCCGTTATAA ATCTACCCTTTCAAAACCTATACCCAAGTCTGATAAATTTAAAAATTCTTTCTGTTGTACAGAATTAAATGAAGAAATCAAACAGTCTCA TTCTTTTAGTTTACAGACACCTTGTTCAAAAGGTAGTGAATTAAGAATGATTAATAAAAATCCTGAAAGAGAAAAGGCTGGGTCTCCAGC TCCATCAAATCGATTAAATGATTCACCTACTTTAAAAAAGCTAGATGAATTGCCTATTTTTAAGTCCGAATTTATAACACATGATAGCCA TGATAGTATTAAGGAATTAGACTCTTTATCTAAAGTGAAGAATGATCAATTAAGAAGTTTTTGTCCCATAGAATTAAATATAAATGGATC TCCTGGGGCAGAATCTGATTTGGCAACATTTTGCACTTCTAAAACTGATGCTGTTTTAATGACTTCTGATGATAGTGTGACTGGATCGGA ATTATCCCCTTTGGTCAAAGCATGCATGCTTTCATCAAATGGATTTCAGAATATTAGTAGGTGCAAAGAAAAAGACTTGGATGATACCTG CATGCTGCATAAGAAGTCAGAAAGCCCATTTAGAGAAACAGAACCTCTGGTGTCACCACACCAAGATAAACTCATGTCTATGCCAGTTAT GACTGTGGATTATTCCAAAACAGTAGTTAAAGAACCAGTTGATACGAGGGTTTCTTGCTGCAAAACCAAAGATTCAGACATATACTGTAC TTTGAACGATAGCAACCCTTCTTTGTGTAACTCTGAAGCTGAAAATATTGAGCCTTCAGTTATGAAGATTTCTTCAAATAGCTTTATGAA TGTGCATTTGGAATCAAAACCAGTTATATGTGATAGTAGAAATTTGACAGATCACTCAAAATTTGCATGTGAAGAATATAAGCAGAGCAT CGGTAGCACTAGTTCAGCTTCTGTTAATCATTTTGATGATTTATATCAACCTATTGGGAGTTCAGGTATTGCTTCATCTCTTCAGAGTCT TCCACCAGGAATAAAGGTGGACAGTCTAACTCTCTTGAAATGCGGAGAGAACACATCTCCAGTTCTGGATGCAGTGCTAAAGAGTAAAAA AAGTTCAGAGTTTTTAAAGCATGCAGGGAAAGAAACAATAGTAGAAGTAGGTAGTGACCTTCCTGATTCAGGAAAGGGATTTGCTTCCAG GGAGAACAGGCGTAATAATGGGTTATCTGGGAAATGTTTGCAAGAGGCTCAAGAAGAAGGGAATTCCATATTGCCTGAAAGAAGAGGAAG ACCAGAAATCTCTTTAGATGAAAGAGGAGAAGGAGGACATGTGCATACTTCTGATGACTCAGAAGTTGTATTTTCTTCTTGTGATTTGAA TTTAACCATGGAAGACAGTGATGGTGTAACTTATGCATTAAAGTGTGACAGTAGTGGTCATGCCCCAGAAATTGTGTCTACAGTTCATGA AGATTATTCTGGCTCTTCTGAAAGTTCAAATGATGAAAGTGATTCAGAAGATACAGATTCGGATGATAGCAGTATTCCAAGAAACCGTCT CCAGTCTGTTGTGGTTGTGCCAAAGAATTCTACTTTGCCCATGGAAGAAACAAGTCCTTGTTCTTCTCGGAGCAGTCAAAGTTATAGACA CTATTCTGACCATTGGGAAGATGAGAGATTGGAGTCAAGGAGACATTTGTATGAGGAAAAATTTGAAAGTATAGCAAGTAAAGCCTGTCC TCAAACTGATAAGTTTTTCCTTCATAAAGGAACAGAGAAGAATCCGGAAATTTCTTTTACACAGTCCAGTAGAAAACAAATAGATAATCG CCTGCCTGAACTTTCTCATCCTCAGAGTGATGGGGTTGATAGTACAAGTCATACAGATGTGAAATCTGACCCTCTGGGTCACCCAAATTC AGAGGAAACCGTGAAAGCCAAAATACCTTCTAGGCAGCAAGAAGAGCTGCCAATTTATTCTTCTGATTTTGAAGATGTCCCAAATAAGTC TTGGCAACAGACCACTTTCCAAAACAGGCCAGATAGTAGACTGGGAAAAACAGAATTGAGTTTTTCTTCCTCTTGTGAGATACCACATGT GGATGGCTTGCACTCATCAGAAGAGCTCAGAAACTTAGGTTGGGACTTCTCTCAAGAAAAGCCTTCTACCACGTATCAGCAACCTGACAG TAGCTATGGAGCTTGTGGTGGACACAAGTATCAGCAAAATGCAGAACAGTATGGTGGGACACGTGATTACTGGCAAGGCAATGGTTACTG GGATCCAAGATCAGGTAGACCTCCTGGAACTGGGGTTGTGTATGATCGAACTCAAGGACAAGTACCAGATTCCCTAACAGATGATCGTGA AGAAGAGGAGAATTGGGATCAACAGGATGGATCCCATTTTTCAGACCAGTCCGATAAATTTCTTCTATCCCTTCAGAAAGACAAGGGGTC AGTGCAAGCACCTGAAATAAGCAGCAATTCCATTAAGGACACTTTAGCTGTGAATGAAAAGAAAGATTTTTCAAAAAACTTAGAAAAAAA TGATATCAAAGATAGAGGGCCTCTTAAAAAAAGGAGGCAGGAAATAGAGAGTGATTCTGAAAGTGATGGTGAGCTTCAGGACAGAAAGAA AGTTAGAGTGGAGGTAGAGCAGGGAGAGACATCAGTGCCCCCAGGTTCAGCACTGGTTGGGCCCTCCTGTGTCATGGATGACTTCAGGGA CCCACAGCGATGGAAGGAATGTGCCAAGCAAGGGAAAATGCCATGTTACTTTGATCTTATTGAAGAAAATGTTTATTTAACAGAAAGAAA GAAGAATAAATCTCATCGAGATATTAAGCGAATGCAGTGTGAGTGTACACCTCTTTCTAAAGATGAAAGAGCTCAAGGTGAAATAGCATG TGGGGAAGATTGTCTTAATCGTCTTCTCATGATTGAATGTTCTTCTCGGTGTCCAAATGGGGATTATTGTTCCAATAGACGGTTTCAGAG AAAACAGCATGCAGATGTGGAAGTCATACTCACAGAAAAGAAAGGCTGGGGCTTGAGAGCTGCCAAAGACCTTCCTTCGAACACCTTTGT CCTAGAATATTGTGGAGAGGTACTCGATCATAAAGAGTTTAAAGCTCGAGTGAAGGAGTATGCACGAAACAAAAACATCCATTACTATTT CATGGCCCTGAAGAATGATGAGATAATAGATGCCACTCAAAAAGGAAATTGCTCTCGTTTCATGAATCACAGCTGTGAACCAAATTGTGA AACCCAAAAATGGACTGTGAACGGACAACTGAGGGTTGGGTTTTTTACCACCAAACTGGTTCCTTCAGGCTCAGAGTTAACGTTTGACTA TCAGTTCCAGAGATATGGAAAAGAAGCCCAGAAATGTTTCTGCGGATCAGCCAATTGCCGGGGTTACCTGGGAGGAGAAAACAGAGTCAG CATCAGAGCAGCAGGAGGGAAAATGAAGAAGGAACGATCTCGTAAGAAGGATTCAGTGGATGGAGAGCTAGAAGCTCTGATGGAAAATGG TGAGGGTCTCTCTGATAAAAACCAGGTGCTCAGCTTATCCCGGCTAATGGTTAGAATTGAAACTTTGGAGCAGAAACTTACCTGTCTGGA ACTCATACAGAACACACACTCACAGTCCTGCCTGAAGTCCTTTCTGGAACGTCATGGGCTGTCTTTGTTGTGGATCTGGATGGCAGAGCT AGGTGACGGCCGGGAAAGTAACCAGAAGCTTCAGGAAGAGATTATAAAGACTTTGGAACACTTGCCCATTCCTACTAAAAATATGTTGGA GGAAAGCAAAGTACTTCCAATTATTCAACGCTGGTCTCAGACTAAGACTGCTGTCCCTCCGTTGAGTGAAGGAGATGGGTATTCTAGTGA GAATACATCGCGTGCTCATACACCACTCAACACACCTGATCCTTCCACCAAGCTGAGCACAGAAGCTGACACAGACACTCCCAAGAAACT AATGTTTCGCAGACTGAAAATTATAAGTGAAAATAGCATGGACAGTGCAATCTCTGATGCAACCAGTGAGCTAGAAGGCAAGGATGGCAA AGAGGATCTTGATCAATTAGAAAATGTCCCTGTAGAGGAAGAGGAAGAATTGCAGTCACAACAGCTACTCCCACAACAGCTGCCTGAATG CAAAGTTGATAGTGAAACCAACATAGAAGCTAGTAAGCTACCTACATCTGAACCAGAAGCTGACGCTGAAATAGAGCCCAAAGAGAGCAA CGGCACAAAACTAGAAGAACCTATTAATGAAGAAACACCATCCCAAGATGAAGAGGAGGGTGTGTCTGATGTGGAGAGTGAAAGGAGCCA AGAACAGCCAGATAAAACAGTGGATATAAGTGATTTGGCCACCAAACTCCTGGACAGTTGGAAAGACCTAAAGGAGATAAATGGCATCAC CGCGGCACTGGCTGAAGAGCTCTTTGAGAAAGGAGAACAGCTCCTGGGGGCCGGCGAGGTCTTTGCCATTGGACCCCTGCAGCTGTATGC CGTCACGGAGCAGCTGCAGCAGGGAAAGCCCACGTGCGCCAGTGGGGATGCCAAGACCGACCTCGGGCACATCCTGGACTTCACCTGTCG CCTTAAGTACCTTAAGGTTTCTGGCACAGAAGGACCTTTTGGGACCAGCAACATTCAGGAGCAGCTCCTGCCGTTCGACCTATCAATATT CAAGTCCCTGCATCAGGTGGAGATAAGTCACTGTGATGCTAAGCACATCAGAGGGCTGGTCGCATCGAAGCCCACCTTAGCCACGCTGAG TGTCCGCTTCTCAGCAACCTCGATGAAGGAAGTCCTTGTTCCTGAAGCCTCAGAATTTGATGAGTGGGAGCCTGAAGGCACAACCCTAGA AGGCCCTGTGACTGCCGTCATCCCCACTTGGCAGGCATTGACCACGCTTGACCTGAGCCACAACAGCGTCTCCGAGATCGACGAGTCTGT GAAACTGATCCCAAAGATTGAGTTCCTGGACCTGAGTCACAATGGATTGCTGGTTGTGGACAATCTGCAGCACCTGTATAACCTTGTGCA TCTGGACCTGTCCTACAACAAGCTCTCCTCCTTGGAAGGGCTTCACACCAAGCTGGGGAACATCAAGACCTTAAACCTGGCAGGCAACCT CCTAGAGAGTCTGAGTGGCCTGCACAAGCTCTACTCACTGGTCAACCTGGATCTCCGGGACAACAGGATCGAACAGATGGAGGAGGTCCG GAGCATAGGCAGCCTCCCGTGTCTGGAGCACGTGTCTCTGCTGAACAACCCTCTGAGCATCATCCCCGACTACCGGACCAAGGTGCTGGC TCAGTTCGGAGAGAGGGCCTCAGAGGTCTGTCTGGATGACACAGTGACCACAGAGAAGGAGCTGGACACTGTGGAAGTGCTGAAAGCAAT TCAGAAAGCCAAGGAGGTCAAGTCCAAACTGAGCAACCCAGAGAAGAAGGGTGGTGAAGACTCCCGGCTCTCAGCTGCCCCCTGCATCAG ACCCAGCAGCTCCCCTCCCACTGTGGCTCCCGCATCTGCCTCCCTGCCCCAGCCCATCCTCTCTAACCAAGGAATCATGTTCGTTCAGGA GGAGGCCCTGGCCAGCAGCCTCTCGTCCACTGACAGTCTGACTCCCGAGCACCAGCCCATTGCCCAGGGATGTTCTGATTCCTTGGAGTC CATCCCTGCGGGACAGGCAGCTTCCGATGATTTAAGGGACGTGCCAGGAGCTGTTGGTGGTGCAAGCCCAGAACATGCCGAGCCGGAGGT CCAGGTGGTGCCGGGGTCTGGCCAGATCATCTTCCTGCCCTTCACCTGCATTGGCTACACGGCCACCAATCAGGACTTCATCCAGCGCCT GAGCACACTGATCCGGCAGGCCATCGAGCGGCAGCTGCCTGCCTGGATCGAGGCTGCCAACCAGCGGGAGGAGGGCCAGGGTGAACAGGG CGAGGAGGAGGATGAGGAGGAGGAAGAAGAGGAGGACGTGGCTGAGAACCGCTACTTTGAAATGGGGCCCCCAGACGTGGAGGAGGAGGA GGGAGGAGGCCAGGGGGAGGAAGAGGAGGAGGAAGAGGAGGATGAAGAGGCCGAGGAGGAGCGCCTGGCTCTGGAATGGGCCCTGGGCGC GGACGAGGACTTCCTGCTGGAGCACATCCGCATCCTCAAGGTGCTGTGGTGCTTCCTGATCCATGTGCAGGGCAGTATCCGCCAGTTCGC CGCCTGCCTTGTGCTCACCGACTTCGGCATCGCAGTCTTCGAGATCCCGCACCAGGAGTCTCGGGGCAGCAGCCAGCACATCCTCTCCTC CCTGCGCTTTGTCTTTTGCTTCCCGCATGGCGACCTCACCGAGTTTGGCTTCCTCATGCCGGAGCTGTGTCTGGTGCTCAAGGTACGGCA CAGTGAGAACACGCTCTTCATTATCTCGGACGCCGCCAACCTGCACGAGTTCCACGCGGACCTGCGCTCATGCTTTGCACCCCAGCACAT GGCCATGCTGTGTAGCCCCATCCTCTACGGCAGCCACACCAGCCTGCAGGAGTTCCTGCGCCAGCTGCTCACCTTCTACAAGGTGGCTGG CGGCTGCCAGGAGCGCAGCCAGGGCTGCTTCCCCGTCTACCTGGTCTACAGTGACAAGCGCATGGTGCAGACGGCCGCCGGGGACTACTC AGGCAACATCGAGTGGGCCAGCTGCACACTCTGTTCAGCCGTGCGGCGCTCCTGCTGCGCGCCCTCTGAGGCCGTCAAGTCCGCCGCCAT CCCCTACTGGCTGTTGCTCACGCCCCAGCACCTCAACGTCATCAAGGCCGACTTCAACCCCATGCCCAACCGTGGCACCCACAACTGTCG CAACCGCAACAGCTTCAAGCTCAGCCGTGTGCCGCTCTCCACCGTGCTGCTGGACCCCACACGCAGCTGTACCCAGCCTCGGGGCGCCTT TGCTGATGGCCACGTGCTAGAGCTGCTCGTGGGGTACCGCTTTGTCACTGCCATCTTCGTGCTGCCCCACGAGAAGTTCCACTTCCTGCG CGTCTACAACCAGCTGCGGGCCTCGCTGCAGGACCTGAAGACTGTGGTCATCGCCAAGACCCCCGGGACGGGAGGCAGCCCCCAGGGCTC CTTTGCGGATGGCCAGCCTGCCGAGCGCAGGGCCAGCAATGACCAGCGTCCCCAGGAGGTCCCAGCAGAGGCTCTGGCCCCGGCCCCAGC GGAAGTCCCAGCTCCAGCCCCTGCAGCAGCCTCAGCCTCAGGCCCAGCGAAGACTCCGGCCCCAGCAGAGGCCTCAACTTCAGCTTTGGT CCCAGAGGAGACGCCAGTGGAAGCTCCAGCCCCACCCCCAGCCGAGGCCCCTGCCCAGTACCCGAGTGAGCACCTCATCCAGGCCACCTC GGAGGAGAATCAGATCCCCTCGCACTTGCCTGCCTGCCCGTCGCTCCGGCACGTCGCCAGCCTGCGGGGCAGCGCCATCATCGAGCTCTT CCACAGCAGCATTGCTGAGGTTGAAAACGAGGAGCTGAGGCACCTCATGTGGTCCTCGGTGGTGTTCTACCAGACCCCAGGGCTGGAGGT GACTGCCTGCGTGCTGCTCTCCACCAAGGCTGTGTACTTTGTGCTCCACGACGGCCTCCGCCGCTACTTCTCAGAGCCACTGCAGGATTT CTGGCATCAGAAAAACACCGACTACAACAACAGCCCTTTCCACATCTCCCAGTGCTTCGTGCTAAAGCTTAGTGACCTGCAGTCAGTCAA TGTGGGGCTTTTCGACCAGCATTTCCGGCTGACGGGTTCCACCCCGATGCAGGTGGTCACGTGCTTGACGCGGGACAGCTACCTGACGCA CTGCTTCCTCCAGCACCTCATGGTCGTGCTGTCCTCTCTGGAACGCACGCCCTCGCCGGAGCCTGTTGACAAGGACTTCTACTCCGAGTT TGGGAACAAGACCACAGGGAAGATGGAGAACTACGAGCTGATCCACTCTAGTCGCGTCAAGTTTACCTACCCCAGTGAGGAGGAGATTGG GGACCTGACGTTCACTGTGGCCCAAAAGATGGCTGAGCCAGAGAAGGCCCCAGCCCTCAGCATCCTGCTGTACGTGCAGGCCTTCCAGGT GGGCATGCCACCCCCTGGGTGCTGCAGGGGCCCCCTGCGCCCCAAGACACTCCTGCTCACCAGCTCCGAGATCTTCCTCCTGGATGAGGA CTGTGTCCACTACCCACTGCCCGAGTTTGCCAAAGAGCCGCCGCAGAGAGACAGGTACCGGCTGGACGATGGCCGCCGCGTCCGGGACCT GGACCGAGTGCTCATGGGCTACCAGACCTACCCGCAGGCCCTCACCCTCGTCTTCGATGACGTGCAAGGTCATGACCTCATGGGCAGTGT CACCCTGGACCACTTTGGGGAGGTGCCAGGTGGCCCGGCTAGAGCCAGCCAGGGCCGTGAAGTCCAGTGGCAGGTGTTTGTCCCCAGTGC TGAGAGCAGAGAGAAGCTCATCTCGCTGTTGGCTCGCCAGTGGGAGGCCCTGTGTGGCCGTGAGCTGCCTGTCGAGCTCACCGGCTAGCC CAGGCCACAGCCAGCCTGTCGTGTCCAGCCTGACGCCTACTGGGGCAGGGCAGCAGGCTTTTGTGTTCTCTAAAAATGTTTTATCCTCCC TTTGGTACCTTAATTTGACTGTCCTCGCAGAGAATGTGAACATGTGTGTGTGTTGTGTTAATTCTTTCTCATGTTGGGAGTGAGAATGCC GGGCCCCTCAGGGCTGTCGGTGTGCTGTCAGCCTCCCACAGGTGGTACAGCCGTGCACACCAGTGTCGTGTCTGCTGTTGTGGGACCGTT GTTAACACGTGACACTGTGGGTCTGACTTTCTCTTCTACACGTCCTTTCCTGAAGTGTCGAGTCCAGTCCTTTGTTGCTGTTGCTGTTGC TGTTGCTGTTGCTGTTGCTGTTGGCATCTTGCTGCTAATCCTGAGGCTGGTAGCAGAATGCACATTGGAAGCTCCCACCCCATATTGTTC TTCAAAGTGGAGGTCTCCCCTGATCCAGACAAGTGGGAGAGCCCGTGGGGGCAGGGGACCTGGAGCTGCCAGCACCAAGCGTGATTCCTG >80877_80877_1_SETD2-NISCH_SETD2_chr3_47125210_ENST00000409792_NISCH_chr3_52504875_ENST00000345716_length(amino acids)=3418AA_BP=2032 LRGGGSRRRLQPLPMKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFS FSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASP PTHAAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKEPPIIIVPESLEADTKQ DTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIE KERDFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYSRSERSHYYDSDRRYHR SSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEA IKRCCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINKNPEREKAGSPA PSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSE LSPLVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIYCT LNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSL PPGIKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQEAQEEGNSILPERRGR PEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRL QSVVVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKNPEISFTQSSRKQIDNR LPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHV DGLHSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVYDRTQGQVPDSLTDDRE EEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKK VRVEVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIAC GEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYF MALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVS IRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAEL GDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKL MFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESN GTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYA VTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATLS VRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSVSEIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVH LDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLA QFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLSAAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQE EALASSLSSTDSLTPEHQPIAQGCSDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRL STLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPPDVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGA DEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRH SENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYS GNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAF ADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTGGSPQGSFADGQPAERRASNDQRPQEVPAEALAPAPA EVPAPAPAAASASGPAKTPAPAEASTSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGSAIIELF HSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVN VGLFDQHFRLTGSTPMQVVTCLTRDSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPSEEEIG DLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEIFLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDL -------------------------------------------------------------- >80877_80877_2_SETD2-NISCH_SETD2_chr3_47125210_ENST00000409792_NISCH_chr3_52504875_ENST00000420808_length(transcript)=8307nt_BP=6103nt GCTGCGGGGAGGGGGCTCGCGTCGCCGTCTCCAGCCGCTCCCGATGAAGCAGCTGCAGCCGCAGCCGCCTCCGAAGATGGGGGATTTCTA CGACCCGGAGCACCCGACCCCTGAAGAAGAAGAAAATGAGGCAAAGATTGAAAATGTGCAGAAAACAGGTTTCATCAAAGGACCAATGTT CAAAGGTGTTGCTTCTAGTCGATTTTTGCCCAAAGGCACCAAAACAAAAGTTAATTTGGAAGAACAGGGACGACAGAAGGTGTCATTCAG CTTCAGCCTTACAAAGAAAACTTTGCAGAATAGGTTTCTCACTGCACTTGGCAATGAAAAGCAAAGTGATACTCCAAACCCTCCAGCTGT ACCTCTTCAGGTAGACTCGACTCCTAAAATGAAAATGGAAATTGGTGATACCTTATCTACTGCAGAAGAATCTTCCCCACCAAAGTCAAG GGTGGAATTGGGCAAAATTCATTTTAAGAAACATCTGCTTCATGTAACATCCAGGCCACTGCTGGCTACTACCACAGCAGTAGCATCTCC ACCTACTCATGCAGCACCATTACCAGCAGTGATAGCAGAATCAACAACTGTAGACTCACCGCCCTCATCTCCGCCTCCACCGCCTCCACC TGCCCAAGCCACAACACTCTCATCACCAGCACCAGTAACAGAGCCAGTGGCCTTGCCACATACACCAATAACAGTTCTAATGGCAGCACC AGTACCCTTACCAGTAGATGTAGCAGTTAGATCTCTGAAAGAACCACCAATTATAATTGTACCAGAATCTTTAGAAGCAGATACTAAGCA GGACACTATATCTAATAGTTTAGAAGAACACGTAACTCAAATATTGAATGAGCAAGCAGATATTTCCTCAAAAAAAGAAGATTCCCATAT TGGGAAGGATGAAGAAATTCCAGATAGTTCTAAGATTAGTCTGAGCTGTAAAAAAACAGGTTCTAAGAAGAAATCCTCACAATCTGAAGG CATCTTTCTTGGTTCAGAATCTGATGAAGATTCTGTACGGACTTCTTCAAGTCAAAGATCACATGATTTAAAATTTTCAGCAAGCATTGA AAAGGAAAGAGATTTTAAAAAGAGCTCAGCACCTTTAAAAAGTGAGGATCTAGGGAAACCTTCACGATCTAAAACAGACAGAGATGATAA ATATTTTAGCTATTCAAAACTTGAAAGAGATACTCGGTATGTATCTTCCCGATGTAGATCAGAAAGAGAGCGACGGCGGAGCAGATCTCA CTCTAGGTCTGAGAGAGGCTCTAGAACTAATTTATCCTATTCCAGGTCAGAACGATCTCATTATTATGACTCTGATCGTCGCTACCATAG GAGCTCCCCTTATCGAGAGAGGACGCGCTATTCTCGGCCATACACAGATAACAGAGCACGAGAGAGTTCTGACTCAGAAGAAGAGTATAA GAAGACATACTCAAGGCGTACCTCATCTCATTCCTCTTCTTACAGAGACCTAAGGACATCATCCTATTCTAAATCTGATCGGGACTGTAA AACTGAGACCTCTTACTTAGAGATGGAAAGAAGAGGCAAGTATTCTTCAAAACTAGAAAGAGAATCTAAAAGGACTTCAGAAAATGAAGC AATTAAAAGATGTTGTTCTCCCCCTAATGAACTGGGATTCCGACGAGGGTCATCATATTCTAAGCATGACAGTAGTGCTTCCCGTTATAA ATCTACCCTTTCAAAACCTATACCCAAGTCTGATAAATTTAAAAATTCTTTCTGTTGTACAGAATTAAATGAAGAAATCAAACAGTCTCA TTCTTTTAGTTTACAGACACCTTGTTCAAAAGGTAGTGAATTAAGAATGATTAATAAAAATCCTGAAAGAGAAAAGGCTGGGTCTCCAGC TCCATCAAATCGATTAAATGATTCACCTACTTTAAAAAAGCTAGATGAATTGCCTATTTTTAAGTCCGAATTTATAACACATGATAGCCA TGATAGTATTAAGGAATTAGACTCTTTATCTAAAGTGAAGAATGATCAATTAAGAAGTTTTTGTCCCATAGAATTAAATATAAATGGATC TCCTGGGGCAGAATCTGATTTGGCAACATTTTGCACTTCTAAAACTGATGCTGTTTTAATGACTTCTGATGATAGTGTGACTGGATCGGA ATTATCCCCTTTGGTCAAAGCATGCATGCTTTCATCAAATGGATTTCAGAATATTAGTAGGTGCAAAGAAAAAGACTTGGATGATACCTG CATGCTGCATAAGAAGTCAGAAAGCCCATTTAGAGAAACAGAACCTCTGGTGTCACCACACCAAGATAAACTCATGTCTATGCCAGTTAT GACTGTGGATTATTCCAAAACAGTAGTTAAAGAACCAGTTGATACGAGGGTTTCTTGCTGCAAAACCAAAGATTCAGACATATACTGTAC TTTGAACGATAGCAACCCTTCTTTGTGTAACTCTGAAGCTGAAAATATTGAGCCTTCAGTTATGAAGATTTCTTCAAATAGCTTTATGAA TGTGCATTTGGAATCAAAACCAGTTATATGTGATAGTAGAAATTTGACAGATCACTCAAAATTTGCATGTGAAGAATATAAGCAGAGCAT CGGTAGCACTAGTTCAGCTTCTGTTAATCATTTTGATGATTTATATCAACCTATTGGGAGTTCAGGTATTGCTTCATCTCTTCAGAGTCT TCCACCAGGAATAAAGGTGGACAGTCTAACTCTCTTGAAATGCGGAGAGAACACATCTCCAGTTCTGGATGCAGTGCTAAAGAGTAAAAA AAGTTCAGAGTTTTTAAAGCATGCAGGGAAAGAAACAATAGTAGAAGTAGGTAGTGACCTTCCTGATTCAGGAAAGGGATTTGCTTCCAG GGAGAACAGGCGTAATAATGGGTTATCTGGGAAATGTTTGCAAGAGGCTCAAGAAGAAGGGAATTCCATATTGCCTGAAAGAAGAGGAAG ACCAGAAATCTCTTTAGATGAAAGAGGAGAAGGAGGACATGTGCATACTTCTGATGACTCAGAAGTTGTATTTTCTTCTTGTGATTTGAA TTTAACCATGGAAGACAGTGATGGTGTAACTTATGCATTAAAGTGTGACAGTAGTGGTCATGCCCCAGAAATTGTGTCTACAGTTCATGA AGATTATTCTGGCTCTTCTGAAAGTTCAAATGATGAAAGTGATTCAGAAGATACAGATTCGGATGATAGCAGTATTCCAAGAAACCGTCT CCAGTCTGTTGTGGTTGTGCCAAAGAATTCTACTTTGCCCATGGAAGAAACAAGTCCTTGTTCTTCTCGGAGCAGTCAAAGTTATAGACA CTATTCTGACCATTGGGAAGATGAGAGATTGGAGTCAAGGAGACATTTGTATGAGGAAAAATTTGAAAGTATAGCAAGTAAAGCCTGTCC TCAAACTGATAAGTTTTTCCTTCATAAAGGAACAGAGAAGAATCCGGAAATTTCTTTTACACAGTCCAGTAGAAAACAAATAGATAATCG CCTGCCTGAACTTTCTCATCCTCAGAGTGATGGGGTTGATAGTACAAGTCATACAGATGTGAAATCTGACCCTCTGGGTCACCCAAATTC AGAGGAAACCGTGAAAGCCAAAATACCTTCTAGGCAGCAAGAAGAGCTGCCAATTTATTCTTCTGATTTTGAAGATGTCCCAAATAAGTC TTGGCAACAGACCACTTTCCAAAACAGGCCAGATAGTAGACTGGGAAAAACAGAATTGAGTTTTTCTTCCTCTTGTGAGATACCACATGT GGATGGCTTGCACTCATCAGAAGAGCTCAGAAACTTAGGTTGGGACTTCTCTCAAGAAAAGCCTTCTACCACGTATCAGCAACCTGACAG TAGCTATGGAGCTTGTGGTGGACACAAGTATCAGCAAAATGCAGAACAGTATGGTGGGACACGTGATTACTGGCAAGGCAATGGTTACTG GGATCCAAGATCAGGTAGACCTCCTGGAACTGGGGTTGTGTATGATCGAACTCAAGGACAAGTACCAGATTCCCTAACAGATGATCGTGA AGAAGAGGAGAATTGGGATCAACAGGATGGATCCCATTTTTCAGACCAGTCCGATAAATTTCTTCTATCCCTTCAGAAAGACAAGGGGTC AGTGCAAGCACCTGAAATAAGCAGCAATTCCATTAAGGACACTTTAGCTGTGAATGAAAAGAAAGATTTTTCAAAAAACTTAGAAAAAAA TGATATCAAAGATAGAGGGCCTCTTAAAAAAAGGAGGCAGGAAATAGAGAGTGATTCTGAAAGTGATGGTGAGCTTCAGGACAGAAAGAA AGTTAGAGTGGAGGTAGAGCAGGGAGAGACATCAGTGCCCCCAGGTTCAGCACTGGTTGGGCCCTCCTGTGTCATGGATGACTTCAGGGA CCCACAGCGATGGAAGGAATGTGCCAAGCAAGGGAAAATGCCATGTTACTTTGATCTTATTGAAGAAAATGTTTATTTAACAGAAAGAAA GAAGAATAAATCTCATCGAGATATTAAGCGAATGCAGTGTGAGTGTACACCTCTTTCTAAAGATGAAAGAGCTCAAGGTGAAATAGCATG TGGGGAAGATTGTCTTAATCGTCTTCTCATGATTGAATGTTCTTCTCGGTGTCCAAATGGGGATTATTGTTCCAATAGACGGTTTCAGAG AAAACAGCATGCAGATGTGGAAGTCATACTCACAGAAAAGAAAGGCTGGGGCTTGAGAGCTGCCAAAGACCTTCCTTCGAACACCTTTGT CCTAGAATATTGTGGAGAGGTACTCGATCATAAAGAGTTTAAAGCTCGAGTGAAGGAGTATGCACGAAACAAAAACATCCATTACTATTT CATGGCCCTGAAGAATGATGAGATAATAGATGCCACTCAAAAAGGAAATTGCTCTCGTTTCATGAATCACAGCTGTGAACCAAATTGTGA AACCCAAAAATGGACTGTGAACGGACAACTGAGGGTTGGGTTTTTTACCACCAAACTGGTTCCTTCAGGCTCAGAGTTAACGTTTGACTA TCAGTTCCAGAGATATGGAAAAGAAGCCCAGAAATGTTTCTGCGGATCAGCCAATTGCCGGGGTTACCTGGGAGGAGAAAACAGAGTCAG CATCAGAGCAGCAGGAGGGAAAATGAAGAAGGAACGATCTCGTAAGAAGGATTCAGTGGATGGAGAGCTAGAAGCTCTGATGGAAAATGG TGAGGGTCTCTCTGATAAAAACCAGGTGCTCAGCTTATCCCGGCTAATGGTTAGAATTGAAACTTTGGAGCAGAAACTTACCTGTCTGGA ACTCATACAGAACACACACTCACAGTCCTGCCTGAAGTCCTTTCTGGAACGTCATGGGCTGTCTTTGTTGTGGATCTGGATGGCAGAGCT AGGTGACGGCCGGGAAAGTAACCAGAAGCTTCAGGAAGAGATTATAAAGACTTTGGAACACTTGCCCATTCCTACTAAAAATATGTTGGA GGAAAGCAAAGTACTTCCAATTATTCAACGCTGGTCTCAGACTAAGACTGCTGTCCCTCCGTTGAGTGAAGGAGATGGGTATTCTAGTGA GAATACATCGCGTGCTCATACACCACTCAACACACCTGATCCTTCCACCAAGCTGAGCACAGAAGCTGACACAGACACTCCCAAGAAACT AATGTTTCGCAGACTGAAAATTATAAGTGAAAATAGCATGGACAGTGCAATCTCTGATGCAACCAGTGAGCTAGAAGGCAAGGATGGCAA AGAGGATCTTGATCAATTAGAAAATGTCCCTGTAGAGGAAGAGGAAGAATTGCAGTCACAACAGCTACTCCCACAACAGCTGCCTGAATG CAAAGTTGATAGTGAAACCAACATAGAAGCTAGTAAGCTACCTACATCTGAACCAGAAGCTGACGCTGAAATAGAGCCCAAAGAGAGCAA CGGCACAAAACTAGAAGAACCTATTAATGAAGAAACACCATCCCAAGATGAAGAGGAGGGTGTGTCTGATGTGGAGAGTGAAAGGAGCCA AGAACAGCCAGATAAAACAGTGGATATAAGTGATTTGGCCACCAAACTCCTGGACAGTTGGAAAGACCTAAAGGAGATAAATGGCATCAC CGCGGCACTGGCTGAAGAGCTCTTTGAGAAAGGAGAACAGCTCCTGGGGGCCGGCGAGGTCTTTGCCATTGGACCCCTGCAGCTGTATGC CGTCACGGAGCAGCTGCAGCAGGGAAAGCCCACGTGCGCCAGTGGGGATGCCAAGACCGACCTCGGGCACATCCTGGACTTCACCTGTCG CCTTAAGTACCTTAAGGTTTCTGGCACAGAAGGACCTTTTGGGACCAGCAACATTCAGGAGCAGCTCCTGCCGTTCGACCTATCAATATT CAAGTCCCTGCATCAGGTGGAGATAAGTCACTGTGATGCTAAGCACATCAGAGGGCTGGTCGCATCGAAGCCCACCTTAGCCACGCTGAG TGTCCGCTTCTCAGCAACCTCGATGAAGGAAGTCCTTGTTCCTGAAGCCTCAGAATTTGATGAGTGGGAGCCTGAAGGCACAACCCTAGA AGGCCCTGTGACTGCCGTCATCCCCACTTGGCAGGCATTGACCACGCTTGACCTGAGCCACAACAGCGTCTCCGAGATCGACGAGTCTGT GAAACTGATCCCAAAGATTGAGTTCCTGGACCTGAGTCACAATGGATTGCTGGTTGTGGACAATCTGCAGCACCTGTATAACCTTGTGCA TCTGGACCTGTCCTACAACAAGCTCTCCTCCTTGGAAGGGCTTCACACCAAGCTGGGGAACATCAAGACCTTAAACCTGGCAGGCAACCT CCTAGAGAGTCTGAGTGGCCTGCACAAGCTCTACTCACTGGTCAACCTGGATCTCCGGGACAACAGGATCGAACAGATGGAGGAGGTCCG GAGCATAGGCAGCCTCCCGTGTCTGGAGCACGTGTCTCTGCTGAACAACCCTCTGAGCATCATCCCCGACTACCGGACCAAGGTGCTGGC TCAGTTCGGAGAGAGGGCCTCAGAGGTCTGTCTGGATGACACAGTGACCACAGAGAAGGAGCTGGACACTGTGGAAGTGCTGAAAGCAAT TCAGAAAGCCAAGGAGGTCAAGTCCAAACTGAGCAACCCAGAGAAGAAGGGTGGTGAAGACTCCCGGCTCTCAGCTGCCCCCTGCATCAG ACCCAGCAGCTCCCCTCCCACTGTGGCTCCCGCATCTGCCTCCCTGCCCCAGCCCATCCTCTCTAACCAAGGCATCCTCGGAGATGAGTG AGTGAAGCAGGTCTCATGAGCGTGTCTGCTGGCCCGGCCCCCACGGAAGAGGGGAGGGTGTGCCGTCCCGAGTGGAGCCGAGGCTCGGGA CACGCAGGAAAGGACGCCGCCTGCCCGGGCTCCTGGAGACGCAGAACTTGGTGTGAGGTCTTGGGAAAACAGTTCAACCCGATGTTTTAA GAGCCAGAAAAACATTCCCACCCCTTGACCTGGTAACCCCACTGGTGGGGATTTTCTCTTAGAGGGATAAGATACCGGGAAGGGGAGGTG AAATGCTCACCACTGCCAAAACACGGGCTGCAACTGCAACATCGGAGGATGAGAGGGAGAGTCGGCTGTGGTGCAGAATGCTCAGCAGCC CTCCCAGCAGGGACAGGAAGACTGGGCAGGAAGAGGGGAGAAGCATTCAAGTTAAGGCAAAAGGCCCAACGCAGAGCAGCACACTGAGGT CACACCTGTGAGATGTGGAAGAGAATTCCTGAGCGTGGAGCGATGGGGTTAGGTGCCAGGATGATTGCCCATTTTGCTTCTGTCAGACTC TTGACTAAGGATTTCTGGTTGCATTTTATTACATAAAAGCCAGGGAGGTTATATCACGGTGAGAAAGCTTCCCTGACGCTGCCTCCTGTA GCGCAGCCAAGCGAGCCTGTGGAGGTACCATATGACTGTAGGCCTCTGGGGACAGGGAGCTGCATCTGCTTCTCAAGGCCAGGGACACAG CCATTTCTGCCAGCATCTGTTGATCAGTGAGTGAGTGAGTGGGCAGGTAGAGCAGGAGCCAGTGAAGAGCAGGCCCTGGATGGGTGGGGA TGCACCATGTCCCCAGGCTGCAGCTGCAGGCAGCCCCCCACATTGTCGGAGAAGCCTCTGCACCAGCTCAGCCCCCTCCTCACTCCCCTT GTGCCCTGGGGACACTCTGCAGAGGGGCACTCTGCAGTCTGTCCCCGCCATCGCTGGACTTCTGGACATGGCCTCCAGATTTGCACCTCT >80877_80877_2_SETD2-NISCH_SETD2_chr3_47125210_ENST00000409792_NISCH_chr3_52504875_ENST00000420808_length(amino acids)=2429AA_BP=2032 LRGGGSRRRLQPLPMKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFS FSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASP PTHAAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKEPPIIIVPESLEADTKQ DTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIE KERDFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYSRSERSHYYDSDRRYHR SSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEA IKRCCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINKNPEREKAGSPA PSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSE LSPLVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIYCT LNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSL PPGIKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQEAQEEGNSILPERRGR PEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRL QSVVVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKNPEISFTQSSRKQIDNR LPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHV DGLHSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVYDRTQGQVPDSLTDDRE EEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKK VRVEVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIAC GEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYF MALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVS IRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAEL GDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKL MFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESN GTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYA VTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATLS VRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSVSEIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVH LDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLA -------------------------------------------------------------- >80877_80877_3_SETD2-NISCH_SETD2_chr3_47125210_ENST00000409792_NISCH_chr3_52504875_ENST00000479054_length(transcript)=10844nt_BP=6103nt GCTGCGGGGAGGGGGCTCGCGTCGCCGTCTCCAGCCGCTCCCGATGAAGCAGCTGCAGCCGCAGCCGCCTCCGAAGATGGGGGATTTCTA CGACCCGGAGCACCCGACCCCTGAAGAAGAAGAAAATGAGGCAAAGATTGAAAATGTGCAGAAAACAGGTTTCATCAAAGGACCAATGTT CAAAGGTGTTGCTTCTAGTCGATTTTTGCCCAAAGGCACCAAAACAAAAGTTAATTTGGAAGAACAGGGACGACAGAAGGTGTCATTCAG CTTCAGCCTTACAAAGAAAACTTTGCAGAATAGGTTTCTCACTGCACTTGGCAATGAAAAGCAAAGTGATACTCCAAACCCTCCAGCTGT ACCTCTTCAGGTAGACTCGACTCCTAAAATGAAAATGGAAATTGGTGATACCTTATCTACTGCAGAAGAATCTTCCCCACCAAAGTCAAG GGTGGAATTGGGCAAAATTCATTTTAAGAAACATCTGCTTCATGTAACATCCAGGCCACTGCTGGCTACTACCACAGCAGTAGCATCTCC ACCTACTCATGCAGCACCATTACCAGCAGTGATAGCAGAATCAACAACTGTAGACTCACCGCCCTCATCTCCGCCTCCACCGCCTCCACC TGCCCAAGCCACAACACTCTCATCACCAGCACCAGTAACAGAGCCAGTGGCCTTGCCACATACACCAATAACAGTTCTAATGGCAGCACC AGTACCCTTACCAGTAGATGTAGCAGTTAGATCTCTGAAAGAACCACCAATTATAATTGTACCAGAATCTTTAGAAGCAGATACTAAGCA GGACACTATATCTAATAGTTTAGAAGAACACGTAACTCAAATATTGAATGAGCAAGCAGATATTTCCTCAAAAAAAGAAGATTCCCATAT TGGGAAGGATGAAGAAATTCCAGATAGTTCTAAGATTAGTCTGAGCTGTAAAAAAACAGGTTCTAAGAAGAAATCCTCACAATCTGAAGG CATCTTTCTTGGTTCAGAATCTGATGAAGATTCTGTACGGACTTCTTCAAGTCAAAGATCACATGATTTAAAATTTTCAGCAAGCATTGA AAAGGAAAGAGATTTTAAAAAGAGCTCAGCACCTTTAAAAAGTGAGGATCTAGGGAAACCTTCACGATCTAAAACAGACAGAGATGATAA ATATTTTAGCTATTCAAAACTTGAAAGAGATACTCGGTATGTATCTTCCCGATGTAGATCAGAAAGAGAGCGACGGCGGAGCAGATCTCA CTCTAGGTCTGAGAGAGGCTCTAGAACTAATTTATCCTATTCCAGGTCAGAACGATCTCATTATTATGACTCTGATCGTCGCTACCATAG GAGCTCCCCTTATCGAGAGAGGACGCGCTATTCTCGGCCATACACAGATAACAGAGCACGAGAGAGTTCTGACTCAGAAGAAGAGTATAA GAAGACATACTCAAGGCGTACCTCATCTCATTCCTCTTCTTACAGAGACCTAAGGACATCATCCTATTCTAAATCTGATCGGGACTGTAA AACTGAGACCTCTTACTTAGAGATGGAAAGAAGAGGCAAGTATTCTTCAAAACTAGAAAGAGAATCTAAAAGGACTTCAGAAAATGAAGC AATTAAAAGATGTTGTTCTCCCCCTAATGAACTGGGATTCCGACGAGGGTCATCATATTCTAAGCATGACAGTAGTGCTTCCCGTTATAA ATCTACCCTTTCAAAACCTATACCCAAGTCTGATAAATTTAAAAATTCTTTCTGTTGTACAGAATTAAATGAAGAAATCAAACAGTCTCA TTCTTTTAGTTTACAGACACCTTGTTCAAAAGGTAGTGAATTAAGAATGATTAATAAAAATCCTGAAAGAGAAAAGGCTGGGTCTCCAGC TCCATCAAATCGATTAAATGATTCACCTACTTTAAAAAAGCTAGATGAATTGCCTATTTTTAAGTCCGAATTTATAACACATGATAGCCA TGATAGTATTAAGGAATTAGACTCTTTATCTAAAGTGAAGAATGATCAATTAAGAAGTTTTTGTCCCATAGAATTAAATATAAATGGATC TCCTGGGGCAGAATCTGATTTGGCAACATTTTGCACTTCTAAAACTGATGCTGTTTTAATGACTTCTGATGATAGTGTGACTGGATCGGA ATTATCCCCTTTGGTCAAAGCATGCATGCTTTCATCAAATGGATTTCAGAATATTAGTAGGTGCAAAGAAAAAGACTTGGATGATACCTG CATGCTGCATAAGAAGTCAGAAAGCCCATTTAGAGAAACAGAACCTCTGGTGTCACCACACCAAGATAAACTCATGTCTATGCCAGTTAT GACTGTGGATTATTCCAAAACAGTAGTTAAAGAACCAGTTGATACGAGGGTTTCTTGCTGCAAAACCAAAGATTCAGACATATACTGTAC TTTGAACGATAGCAACCCTTCTTTGTGTAACTCTGAAGCTGAAAATATTGAGCCTTCAGTTATGAAGATTTCTTCAAATAGCTTTATGAA TGTGCATTTGGAATCAAAACCAGTTATATGTGATAGTAGAAATTTGACAGATCACTCAAAATTTGCATGTGAAGAATATAAGCAGAGCAT CGGTAGCACTAGTTCAGCTTCTGTTAATCATTTTGATGATTTATATCAACCTATTGGGAGTTCAGGTATTGCTTCATCTCTTCAGAGTCT TCCACCAGGAATAAAGGTGGACAGTCTAACTCTCTTGAAATGCGGAGAGAACACATCTCCAGTTCTGGATGCAGTGCTAAAGAGTAAAAA AAGTTCAGAGTTTTTAAAGCATGCAGGGAAAGAAACAATAGTAGAAGTAGGTAGTGACCTTCCTGATTCAGGAAAGGGATTTGCTTCCAG GGAGAACAGGCGTAATAATGGGTTATCTGGGAAATGTTTGCAAGAGGCTCAAGAAGAAGGGAATTCCATATTGCCTGAAAGAAGAGGAAG ACCAGAAATCTCTTTAGATGAAAGAGGAGAAGGAGGACATGTGCATACTTCTGATGACTCAGAAGTTGTATTTTCTTCTTGTGATTTGAA TTTAACCATGGAAGACAGTGATGGTGTAACTTATGCATTAAAGTGTGACAGTAGTGGTCATGCCCCAGAAATTGTGTCTACAGTTCATGA AGATTATTCTGGCTCTTCTGAAAGTTCAAATGATGAAAGTGATTCAGAAGATACAGATTCGGATGATAGCAGTATTCCAAGAAACCGTCT CCAGTCTGTTGTGGTTGTGCCAAAGAATTCTACTTTGCCCATGGAAGAAACAAGTCCTTGTTCTTCTCGGAGCAGTCAAAGTTATAGACA CTATTCTGACCATTGGGAAGATGAGAGATTGGAGTCAAGGAGACATTTGTATGAGGAAAAATTTGAAAGTATAGCAAGTAAAGCCTGTCC TCAAACTGATAAGTTTTTCCTTCATAAAGGAACAGAGAAGAATCCGGAAATTTCTTTTACACAGTCCAGTAGAAAACAAATAGATAATCG CCTGCCTGAACTTTCTCATCCTCAGAGTGATGGGGTTGATAGTACAAGTCATACAGATGTGAAATCTGACCCTCTGGGTCACCCAAATTC AGAGGAAACCGTGAAAGCCAAAATACCTTCTAGGCAGCAAGAAGAGCTGCCAATTTATTCTTCTGATTTTGAAGATGTCCCAAATAAGTC TTGGCAACAGACCACTTTCCAAAACAGGCCAGATAGTAGACTGGGAAAAACAGAATTGAGTTTTTCTTCCTCTTGTGAGATACCACATGT GGATGGCTTGCACTCATCAGAAGAGCTCAGAAACTTAGGTTGGGACTTCTCTCAAGAAAAGCCTTCTACCACGTATCAGCAACCTGACAG TAGCTATGGAGCTTGTGGTGGACACAAGTATCAGCAAAATGCAGAACAGTATGGTGGGACACGTGATTACTGGCAAGGCAATGGTTACTG GGATCCAAGATCAGGTAGACCTCCTGGAACTGGGGTTGTGTATGATCGAACTCAAGGACAAGTACCAGATTCCCTAACAGATGATCGTGA AGAAGAGGAGAATTGGGATCAACAGGATGGATCCCATTTTTCAGACCAGTCCGATAAATTTCTTCTATCCCTTCAGAAAGACAAGGGGTC AGTGCAAGCACCTGAAATAAGCAGCAATTCCATTAAGGACACTTTAGCTGTGAATGAAAAGAAAGATTTTTCAAAAAACTTAGAAAAAAA TGATATCAAAGATAGAGGGCCTCTTAAAAAAAGGAGGCAGGAAATAGAGAGTGATTCTGAAAGTGATGGTGAGCTTCAGGACAGAAAGAA AGTTAGAGTGGAGGTAGAGCAGGGAGAGACATCAGTGCCCCCAGGTTCAGCACTGGTTGGGCCCTCCTGTGTCATGGATGACTTCAGGGA CCCACAGCGATGGAAGGAATGTGCCAAGCAAGGGAAAATGCCATGTTACTTTGATCTTATTGAAGAAAATGTTTATTTAACAGAAAGAAA GAAGAATAAATCTCATCGAGATATTAAGCGAATGCAGTGTGAGTGTACACCTCTTTCTAAAGATGAAAGAGCTCAAGGTGAAATAGCATG TGGGGAAGATTGTCTTAATCGTCTTCTCATGATTGAATGTTCTTCTCGGTGTCCAAATGGGGATTATTGTTCCAATAGACGGTTTCAGAG AAAACAGCATGCAGATGTGGAAGTCATACTCACAGAAAAGAAAGGCTGGGGCTTGAGAGCTGCCAAAGACCTTCCTTCGAACACCTTTGT CCTAGAATATTGTGGAGAGGTACTCGATCATAAAGAGTTTAAAGCTCGAGTGAAGGAGTATGCACGAAACAAAAACATCCATTACTATTT CATGGCCCTGAAGAATGATGAGATAATAGATGCCACTCAAAAAGGAAATTGCTCTCGTTTCATGAATCACAGCTGTGAACCAAATTGTGA AACCCAAAAATGGACTGTGAACGGACAACTGAGGGTTGGGTTTTTTACCACCAAACTGGTTCCTTCAGGCTCAGAGTTAACGTTTGACTA TCAGTTCCAGAGATATGGAAAAGAAGCCCAGAAATGTTTCTGCGGATCAGCCAATTGCCGGGGTTACCTGGGAGGAGAAAACAGAGTCAG CATCAGAGCAGCAGGAGGGAAAATGAAGAAGGAACGATCTCGTAAGAAGGATTCAGTGGATGGAGAGCTAGAAGCTCTGATGGAAAATGG TGAGGGTCTCTCTGATAAAAACCAGGTGCTCAGCTTATCCCGGCTAATGGTTAGAATTGAAACTTTGGAGCAGAAACTTACCTGTCTGGA ACTCATACAGAACACACACTCACAGTCCTGCCTGAAGTCCTTTCTGGAACGTCATGGGCTGTCTTTGTTGTGGATCTGGATGGCAGAGCT AGGTGACGGCCGGGAAAGTAACCAGAAGCTTCAGGAAGAGATTATAAAGACTTTGGAACACTTGCCCATTCCTACTAAAAATATGTTGGA GGAAAGCAAAGTACTTCCAATTATTCAACGCTGGTCTCAGACTAAGACTGCTGTCCCTCCGTTGAGTGAAGGAGATGGGTATTCTAGTGA GAATACATCGCGTGCTCATACACCACTCAACACACCTGATCCTTCCACCAAGCTGAGCACAGAAGCTGACACAGACACTCCCAAGAAACT AATGTTTCGCAGACTGAAAATTATAAGTGAAAATAGCATGGACAGTGCAATCTCTGATGCAACCAGTGAGCTAGAAGGCAAGGATGGCAA AGAGGATCTTGATCAATTAGAAAATGTCCCTGTAGAGGAAGAGGAAGAATTGCAGTCACAACAGCTACTCCCACAACAGCTGCCTGAATG CAAAGTTGATAGTGAAACCAACATAGAAGCTAGTAAGCTACCTACATCTGAACCAGAAGCTGACGCTGAAATAGAGCCCAAAGAGAGCAA CGGCACAAAACTAGAAGAACCTATTAATGAAGAAACACCATCCCAAGATGAAGAGGAGGGTGTGTCTGATGTGGAGAGTGAAAGGAGCCA AGAACAGCCAGATAAAACAGTGGATATAAGTGATTTGGCCACCAAACTCCTGGACAGTTGGAAAGACCTAAAGGAGATAAATGGCATCAC CGCGGCACTGGCTGAAGAGCTCTTTGAGAAAGGAGAACAGCTCCTGGGGGCCGGCGAGGTCTTTGCCATTGGACCCCTGCAGCTGTATGC CGTCACGGAGCAGCTGCAGCAGGGAAAGCCCACGTGCGCCAGTGGGGATGCCAAGACCGACCTCGGGCACATCCTGGACTTCACCTGTCG CCTTAAGTACCTTAAGGTTTCTGGCACAGAAGGACCTTTTGGGACCAGCAACATTCAGGAGCAGCTCCTGCCGTTCGACCTATCAATATT CAAGTCCCTGCATCAGGTGGAGATAAGTCACTGTGATGCTAAGCACATCAGAGGGCTGGTCGCATCGAAGCCCACCTTAGCCACGCTGAG TGTCCGCTTCTCAGCAACCTCGATGAAGGAAGTCCTTGTTCCTGAAGCCTCAGAATTTGATGAGTGGGAGCCTGAAGGCACAACCCTAGA AGGCCCTGTGACTGCCGTCATCCCCACTTGGCAGGCATTGACCACGCTTGACCTGAGCCACAACAGCGTCTCCGAGATCGACGAGTCTGT GAAACTGATCCCAAAGATTGAGTTCCTGGACCTGAGTCACAATGGATTGCTGGTTGTGGACAATCTGCAGCACCTGTATAACCTTGTGCA TCTGGACCTGTCCTACAACAAGCTCTCCTCCTTGGAAGGGCTTCACACCAAGCTGGGGAACATCAAGACCTTAAACCTGGCAGGCAACCT CCTAGAGAGTCTGAGTGGCCTGCACAAGCTCTACTCACTGGTCAACCTGGATCTCCGGGACAACAGGATCGAACAGATGGAGGAGGTCCG GAGCATAGGCAGCCTCCCGTGTCTGGAGCACGTGTCTCTGCTGAACAACCCTCTGAGCATCATCCCCGACTACCGGACCAAGGTGCTGGC TCAGTTCGGAGAGAGGGCCTCAGAGGTCTGTCTGGATGACACAGTGACCACAGAGAAGGAGCTGGACACTGTGGAAGTGCTGAAAGCAAT TCAGAAAGCCAAGGAGGTCAAGTCCAAACTGAGCAACCCAGAGAAGAAGGGTGGTGAAGACTCCCGGCTCTCAGCTGCCCCCTGCATCAG ACCCAGCAGCTCCCCTCCCACTGTGGCTCCCGCATCTGCCTCCCTGCCCCAGCCCATCCTCTCTAACCAAGGAATCATGTTCGTTCAGGA GGAGGCCCTGGCCAGCAGCCTCTCGTCCACTGACAGTCTGACTCCCGAGCACCAGCCCATTGCCCAGGGATGTTCTGATTCCTTGGAGTC CATCCCTGCGGGACAGGCAGCTTCCGATGATTTAAGGGACGTGCCAGGAGCTGTTGGTGGTGCAAGCCCAGAACATGCCGAGCCGGAGGT CCAGGTGGTGCCGGGGTCTGGCCAGATCATCTTCCTGCCCTTCACCTGCATTGGCTACACGGCCACCAATCAGGACTTCATCCAGCGCCT GAGCACACTGATCCGGCAGGCCATCGAGCGGCAGCTGCCTGCCTGGATCGAGGCTGCCAACCAGCGGGAGGAGGGCCAGGGTGAACAGGG CGAGGAGGAGGATGAGGAGGAGGAAGAAGAGGAGGACGTGGCTGAGAACCGCTACTTTGAAATGGGGCCCCCAGACGTGGAGGAGGAGGA GGGAGGAGGCCAGGGGGAGGAAGAGGAGGAGGAAGAGGAGGATGAAGAGGCCGAGGAGGAGCGCCTGGCTCTGGAATGGGCCCTGGGCGC GGACGAGGACTTCCTGCTGGAGCACATCCGCATCCTCAAGGTGCTGTGGTGCTTCCTGATCCATGTGCAGGGCAGTATCCGCCAGTTCGC CGCCTGCCTTGTGCTCACCGACTTCGGCATCGCAGTCTTCGAGATCCCGCACCAGGAGTCTCGGGGCAGCAGCCAGCACATCCTCTCCTC CCTGCGCTTTGTCTTTTGCTTCCCGCATGGCGACCTCACCGAGTTTGGCTTCCTCATGCCGGAGCTGTGTCTGGTGCTCAAGGTACGGCA CAGTGAGAACACGCTCTTCATTATCTCGGACGCCGCCAACCTGCACGAGTTCCACGCGGACCTGCGCTCATGCTTTGCACCCCAGCACAT GGCCATGCTGTGTAGCCCCATCCTCTACGGCAGCCACACCAGCCTGCAGGAGTTCCTGCGCCAGCTGCTCACCTTCTACAAGGTGGCTGG CGGCTGCCAGGAGCGCAGCCAGGGCTGCTTCCCCGTCTACCTGGTCTACAGTGACAAGCGCATGGTGCAGACGGCCGCCGGGGACTACTC AGGCAACATCGAGTGGGCCAGCTGCACACTCTGTTCAGCCGTGCGGCGCTCCTGCTGCGCGCCCTCTGAGGCCGTCAAGTCCGCCGCCAT CCCCTACTGGCTGTTGCTCACGCCCCAGCACCTCAACGTCATCAAGGCCGACTTCAACCCCATGCCCAACCGTGGCACCCACAACTGTCG CAACCGCAACAGCTTCAAGCTCAGCCGTGTGCCGCTCTCCACCGTGCTGCTGGACCCCACACGCAGCTGTACCCAGCCTCGGGGCGCCTT TGCTGATGGCCACGTGCTAGAGCTGCTCGTGGGGTACCGCTTTGTCACTGCCATCTTCGTGCTGCCCCACGAGAAGTTCCACTTCCTGCG CGTCTACAACCAGCTGCGGGCCTCGCTGCAGGACCTGAAGACTGTGGTCATCGCCAAGACCCCCGGGACGGGAGGCAGCCCCCAGGGCTC CTTTGCGGATGGCCAGCCTGCCGAGCGCAGGGCCAGCAATGACCAGCGTCCCCAGGAGGTCCCAGCAGAGGCTCTGGCCCCGGCCCCAGC GGAAGTCCCAGCTCCAGCCCCTGCAGCAGCCTCAGCCTCAGGCCCAGCGAAGACTCCGGCCCCAGCAGAGGCCTCAACTTCAGCTTTGGT CCCAGAGGAGACGCCAGTGGAAGCTCCAGCCCCACCCCCAGCCGAGGCCCCTGCCCAGTACCCGAGTGAGCACCTCATCCAGGCCACCTC GGAGGAGAATCAGATCCCCTCGCACTTGCCTGCCTGCCCGTCGCTCCGGCACGTCGCCAGCCTGCGGGGCAGCGCCATCATCGAGCTCTT CCACAGCAGCATTGCTGAGGTTGAAAACGAGGAGCTGAGGCACCTCATGTGGTCCTCGGTGGTGTTCTACCAGACCCCAGGGCTGGAGGT GACTGCCTGCGTGCTGCTCTCCACCAAGGCTGTGTACTTTGTGCTCCACGACGGCCTCCGCCGCTACTTCTCAGAGCCACTGCAGGATTT CTGGCATCAGAAAAACACCGACTACAACAACAGCCCTTTCCACATCTCCCAGTGCTTCGTGCTAAAGCTTAGTGACCTGCAGTCAGTCAA TGTGGGGCTTTTCGACCAGCATTTCCGGCTGACGGGTTCCACCCCGATGCAGGTGGTCACGTGCTTGACGCGGGACAGCTACCTGACGCA CTGCTTCCTCCAGCACCTCATGGTCGTGCTGTCCTCTCTGGAACGCACGCCCTCGCCGGAGCCTGTTGACAAGGACTTCTACTCCGAGTT TGGGAACAAGACCACAGGGAAGATGGAGAACTACGAGCTGATCCACTCTAGTCGCGTCAAGTTTACCTACCCCAGTGAGGAGGAGATTGG GGACCTGACGTTCACTGTGGCCCAAAAGATGGCTGAGCCAGAGAAGGCCCCAGCCCTCAGCATCCTGCTGTACGTGCAGGCCTTCCAGGT GGGCATGCCACCCCCTGGGTGCTGCAGGGGCCCCCTGCGCCCCAAGACACTCCTGCTCACCAGCTCCGAGATCTTCCTCCTGGATGAGGA CTGTGTCCACTACCCACTGCCCGAGTTTGCCAAAGAGCCGCCGCAGAGAGACAGGTACCGGCTGGACGATGGCCGCCGCGTCCGGGACCT GGACCGAGTGCTCATGGGCTACCAGACCTACCCGCAGGCCCTCACCCTCGTCTTCGATGACGTGCAAGGTCATGACCTCATGGGCAGTGT CACCCTGGACCACTTTGGGGAGGTGCCAGGTGGCCCGGCTAGAGCCAGCCAGGGCCGTGAAGTCCAGTGGCAGGTGTTTGTCCCCAGTGC TGAGAGCAGAGAGAAGCTCATCTCGCTGTTGGCTCGCCAGTGGGAGGCCCTGTGTGGCCGTGAGCTGCCTGTCGAGCTCACCGGCTAGCC CAGGCCACAGCCAGCCTGTCGTGTCCAGCCTGACGCCTACTGGGGCAGGGCAGCAGGCTTTTGTGTTCTCTAAAAATGTTTTATCCTCCC TTTGGTACCTTAATTTGACTGTCCTCGCAGAGAATGTGAACATGTGTGTGTGTTGTGTTAATTCTTTCTCATGTTGGGAGTGAGAATGCC GGGCCCCTCAGGGCTGTCGGTGTGCTGTCAGCCTCCCACAGGTGGTACAGCCGTGCACACCAGTGTCGTGTCTGCTGTTGTGGGACCGTT GTTAACACGTGACACTGTGGGTCTGACTTTCTCTTCTACACGTCCTTTCCTGAAGTGTCGAGTCCAGTCCTTTGTTGCTGTTGCTGTTGC TGTTGCTGTTGCTGTTGCTGTTGGCATCTTGCTGCTAATCCTGAGGCTGGTAGCAGAATGCACATTGGAAGCTCCCACCCCATATTGTTC TTCAAAGTGGAGGTCTCCCCTGATCCAGACAAGTGGGAGAGCCCGTGGGGGCAGGGGACCTGGAGCTGCCAGCACCAAGCGTGATTCCTG >80877_80877_3_SETD2-NISCH_SETD2_chr3_47125210_ENST00000409792_NISCH_chr3_52504875_ENST00000479054_length(amino acids)=3418AA_BP=2032 LRGGGSRRRLQPLPMKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFS FSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASP PTHAAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKEPPIIIVPESLEADTKQ DTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIE KERDFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYSRSERSHYYDSDRRYHR SSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEA IKRCCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINKNPEREKAGSPA PSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSE LSPLVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIYCT LNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSL PPGIKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQEAQEEGNSILPERRGR PEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRL QSVVVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKNPEISFTQSSRKQIDNR LPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHV DGLHSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVYDRTQGQVPDSLTDDRE EEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKK VRVEVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIAC GEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYF MALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVS IRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAEL GDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKL MFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESN GTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYA VTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATLS VRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSVSEIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVH LDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLA QFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLSAAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQE EALASSLSSTDSLTPEHQPIAQGCSDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRL STLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPPDVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGA DEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRH SENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYS GNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAF ADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTGGSPQGSFADGQPAERRASNDQRPQEVPAEALAPAPA EVPAPAPAAASASGPAKTPAPAEASTSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGSAIIELF HSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVN VGLFDQHFRLTGSTPMQVVTCLTRDSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPSEEEIG DLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEIFLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDL -------------------------------------------------------------- >80877_80877_4_SETD2-NISCH_SETD2_chr3_47125210_ENST00000409792_NISCH_chr3_52504875_ENST00000488380_length(transcript)=8886nt_BP=6103nt GCTGCGGGGAGGGGGCTCGCGTCGCCGTCTCCAGCCGCTCCCGATGAAGCAGCTGCAGCCGCAGCCGCCTCCGAAGATGGGGGATTTCTA CGACCCGGAGCACCCGACCCCTGAAGAAGAAGAAAATGAGGCAAAGATTGAAAATGTGCAGAAAACAGGTTTCATCAAAGGACCAATGTT CAAAGGTGTTGCTTCTAGTCGATTTTTGCCCAAAGGCACCAAAACAAAAGTTAATTTGGAAGAACAGGGACGACAGAAGGTGTCATTCAG CTTCAGCCTTACAAAGAAAACTTTGCAGAATAGGTTTCTCACTGCACTTGGCAATGAAAAGCAAAGTGATACTCCAAACCCTCCAGCTGT ACCTCTTCAGGTAGACTCGACTCCTAAAATGAAAATGGAAATTGGTGATACCTTATCTACTGCAGAAGAATCTTCCCCACCAAAGTCAAG GGTGGAATTGGGCAAAATTCATTTTAAGAAACATCTGCTTCATGTAACATCCAGGCCACTGCTGGCTACTACCACAGCAGTAGCATCTCC ACCTACTCATGCAGCACCATTACCAGCAGTGATAGCAGAATCAACAACTGTAGACTCACCGCCCTCATCTCCGCCTCCACCGCCTCCACC TGCCCAAGCCACAACACTCTCATCACCAGCACCAGTAACAGAGCCAGTGGCCTTGCCACATACACCAATAACAGTTCTAATGGCAGCACC AGTACCCTTACCAGTAGATGTAGCAGTTAGATCTCTGAAAGAACCACCAATTATAATTGTACCAGAATCTTTAGAAGCAGATACTAAGCA GGACACTATATCTAATAGTTTAGAAGAACACGTAACTCAAATATTGAATGAGCAAGCAGATATTTCCTCAAAAAAAGAAGATTCCCATAT TGGGAAGGATGAAGAAATTCCAGATAGTTCTAAGATTAGTCTGAGCTGTAAAAAAACAGGTTCTAAGAAGAAATCCTCACAATCTGAAGG CATCTTTCTTGGTTCAGAATCTGATGAAGATTCTGTACGGACTTCTTCAAGTCAAAGATCACATGATTTAAAATTTTCAGCAAGCATTGA AAAGGAAAGAGATTTTAAAAAGAGCTCAGCACCTTTAAAAAGTGAGGATCTAGGGAAACCTTCACGATCTAAAACAGACAGAGATGATAA ATATTTTAGCTATTCAAAACTTGAAAGAGATACTCGGTATGTATCTTCCCGATGTAGATCAGAAAGAGAGCGACGGCGGAGCAGATCTCA CTCTAGGTCTGAGAGAGGCTCTAGAACTAATTTATCCTATTCCAGGTCAGAACGATCTCATTATTATGACTCTGATCGTCGCTACCATAG GAGCTCCCCTTATCGAGAGAGGACGCGCTATTCTCGGCCATACACAGATAACAGAGCACGAGAGAGTTCTGACTCAGAAGAAGAGTATAA GAAGACATACTCAAGGCGTACCTCATCTCATTCCTCTTCTTACAGAGACCTAAGGACATCATCCTATTCTAAATCTGATCGGGACTGTAA AACTGAGACCTCTTACTTAGAGATGGAAAGAAGAGGCAAGTATTCTTCAAAACTAGAAAGAGAATCTAAAAGGACTTCAGAAAATGAAGC AATTAAAAGATGTTGTTCTCCCCCTAATGAACTGGGATTCCGACGAGGGTCATCATATTCTAAGCATGACAGTAGTGCTTCCCGTTATAA ATCTACCCTTTCAAAACCTATACCCAAGTCTGATAAATTTAAAAATTCTTTCTGTTGTACAGAATTAAATGAAGAAATCAAACAGTCTCA TTCTTTTAGTTTACAGACACCTTGTTCAAAAGGTAGTGAATTAAGAATGATTAATAAAAATCCTGAAAGAGAAAAGGCTGGGTCTCCAGC TCCATCAAATCGATTAAATGATTCACCTACTTTAAAAAAGCTAGATGAATTGCCTATTTTTAAGTCCGAATTTATAACACATGATAGCCA TGATAGTATTAAGGAATTAGACTCTTTATCTAAAGTGAAGAATGATCAATTAAGAAGTTTTTGTCCCATAGAATTAAATATAAATGGATC TCCTGGGGCAGAATCTGATTTGGCAACATTTTGCACTTCTAAAACTGATGCTGTTTTAATGACTTCTGATGATAGTGTGACTGGATCGGA ATTATCCCCTTTGGTCAAAGCATGCATGCTTTCATCAAATGGATTTCAGAATATTAGTAGGTGCAAAGAAAAAGACTTGGATGATACCTG CATGCTGCATAAGAAGTCAGAAAGCCCATTTAGAGAAACAGAACCTCTGGTGTCACCACACCAAGATAAACTCATGTCTATGCCAGTTAT GACTGTGGATTATTCCAAAACAGTAGTTAAAGAACCAGTTGATACGAGGGTTTCTTGCTGCAAAACCAAAGATTCAGACATATACTGTAC TTTGAACGATAGCAACCCTTCTTTGTGTAACTCTGAAGCTGAAAATATTGAGCCTTCAGTTATGAAGATTTCTTCAAATAGCTTTATGAA TGTGCATTTGGAATCAAAACCAGTTATATGTGATAGTAGAAATTTGACAGATCACTCAAAATTTGCATGTGAAGAATATAAGCAGAGCAT CGGTAGCACTAGTTCAGCTTCTGTTAATCATTTTGATGATTTATATCAACCTATTGGGAGTTCAGGTATTGCTTCATCTCTTCAGAGTCT TCCACCAGGAATAAAGGTGGACAGTCTAACTCTCTTGAAATGCGGAGAGAACACATCTCCAGTTCTGGATGCAGTGCTAAAGAGTAAAAA AAGTTCAGAGTTTTTAAAGCATGCAGGGAAAGAAACAATAGTAGAAGTAGGTAGTGACCTTCCTGATTCAGGAAAGGGATTTGCTTCCAG GGAGAACAGGCGTAATAATGGGTTATCTGGGAAATGTTTGCAAGAGGCTCAAGAAGAAGGGAATTCCATATTGCCTGAAAGAAGAGGAAG ACCAGAAATCTCTTTAGATGAAAGAGGAGAAGGAGGACATGTGCATACTTCTGATGACTCAGAAGTTGTATTTTCTTCTTGTGATTTGAA TTTAACCATGGAAGACAGTGATGGTGTAACTTATGCATTAAAGTGTGACAGTAGTGGTCATGCCCCAGAAATTGTGTCTACAGTTCATGA AGATTATTCTGGCTCTTCTGAAAGTTCAAATGATGAAAGTGATTCAGAAGATACAGATTCGGATGATAGCAGTATTCCAAGAAACCGTCT CCAGTCTGTTGTGGTTGTGCCAAAGAATTCTACTTTGCCCATGGAAGAAACAAGTCCTTGTTCTTCTCGGAGCAGTCAAAGTTATAGACA CTATTCTGACCATTGGGAAGATGAGAGATTGGAGTCAAGGAGACATTTGTATGAGGAAAAATTTGAAAGTATAGCAAGTAAAGCCTGTCC TCAAACTGATAAGTTTTTCCTTCATAAAGGAACAGAGAAGAATCCGGAAATTTCTTTTACACAGTCCAGTAGAAAACAAATAGATAATCG CCTGCCTGAACTTTCTCATCCTCAGAGTGATGGGGTTGATAGTACAAGTCATACAGATGTGAAATCTGACCCTCTGGGTCACCCAAATTC AGAGGAAACCGTGAAAGCCAAAATACCTTCTAGGCAGCAAGAAGAGCTGCCAATTTATTCTTCTGATTTTGAAGATGTCCCAAATAAGTC TTGGCAACAGACCACTTTCCAAAACAGGCCAGATAGTAGACTGGGAAAAACAGAATTGAGTTTTTCTTCCTCTTGTGAGATACCACATGT GGATGGCTTGCACTCATCAGAAGAGCTCAGAAACTTAGGTTGGGACTTCTCTCAAGAAAAGCCTTCTACCACGTATCAGCAACCTGACAG TAGCTATGGAGCTTGTGGTGGACACAAGTATCAGCAAAATGCAGAACAGTATGGTGGGACACGTGATTACTGGCAAGGCAATGGTTACTG GGATCCAAGATCAGGTAGACCTCCTGGAACTGGGGTTGTGTATGATCGAACTCAAGGACAAGTACCAGATTCCCTAACAGATGATCGTGA AGAAGAGGAGAATTGGGATCAACAGGATGGATCCCATTTTTCAGACCAGTCCGATAAATTTCTTCTATCCCTTCAGAAAGACAAGGGGTC AGTGCAAGCACCTGAAATAAGCAGCAATTCCATTAAGGACACTTTAGCTGTGAATGAAAAGAAAGATTTTTCAAAAAACTTAGAAAAAAA TGATATCAAAGATAGAGGGCCTCTTAAAAAAAGGAGGCAGGAAATAGAGAGTGATTCTGAAAGTGATGGTGAGCTTCAGGACAGAAAGAA AGTTAGAGTGGAGGTAGAGCAGGGAGAGACATCAGTGCCCCCAGGTTCAGCACTGGTTGGGCCCTCCTGTGTCATGGATGACTTCAGGGA CCCACAGCGATGGAAGGAATGTGCCAAGCAAGGGAAAATGCCATGTTACTTTGATCTTATTGAAGAAAATGTTTATTTAACAGAAAGAAA GAAGAATAAATCTCATCGAGATATTAAGCGAATGCAGTGTGAGTGTACACCTCTTTCTAAAGATGAAAGAGCTCAAGGTGAAATAGCATG TGGGGAAGATTGTCTTAATCGTCTTCTCATGATTGAATGTTCTTCTCGGTGTCCAAATGGGGATTATTGTTCCAATAGACGGTTTCAGAG AAAACAGCATGCAGATGTGGAAGTCATACTCACAGAAAAGAAAGGCTGGGGCTTGAGAGCTGCCAAAGACCTTCCTTCGAACACCTTTGT CCTAGAATATTGTGGAGAGGTACTCGATCATAAAGAGTTTAAAGCTCGAGTGAAGGAGTATGCACGAAACAAAAACATCCATTACTATTT CATGGCCCTGAAGAATGATGAGATAATAGATGCCACTCAAAAAGGAAATTGCTCTCGTTTCATGAATCACAGCTGTGAACCAAATTGTGA AACCCAAAAATGGACTGTGAACGGACAACTGAGGGTTGGGTTTTTTACCACCAAACTGGTTCCTTCAGGCTCAGAGTTAACGTTTGACTA TCAGTTCCAGAGATATGGAAAAGAAGCCCAGAAATGTTTCTGCGGATCAGCCAATTGCCGGGGTTACCTGGGAGGAGAAAACAGAGTCAG CATCAGAGCAGCAGGAGGGAAAATGAAGAAGGAACGATCTCGTAAGAAGGATTCAGTGGATGGAGAGCTAGAAGCTCTGATGGAAAATGG TGAGGGTCTCTCTGATAAAAACCAGGTGCTCAGCTTATCCCGGCTAATGGTTAGAATTGAAACTTTGGAGCAGAAACTTACCTGTCTGGA ACTCATACAGAACACACACTCACAGTCCTGCCTGAAGTCCTTTCTGGAACGTCATGGGCTGTCTTTGTTGTGGATCTGGATGGCAGAGCT AGGTGACGGCCGGGAAAGTAACCAGAAGCTTCAGGAAGAGATTATAAAGACTTTGGAACACTTGCCCATTCCTACTAAAAATATGTTGGA GGAAAGCAAAGTACTTCCAATTATTCAACGCTGGTCTCAGACTAAGACTGCTGTCCCTCCGTTGAGTGAAGGAGATGGGTATTCTAGTGA GAATACATCGCGTGCTCATACACCACTCAACACACCTGATCCTTCCACCAAGCTGAGCACAGAAGCTGACACAGACACTCCCAAGAAACT AATGTTTCGCAGACTGAAAATTATAAGTGAAAATAGCATGGACAGTGCAATCTCTGATGCAACCAGTGAGCTAGAAGGCAAGGATGGCAA AGAGGATCTTGATCAATTAGAAAATGTCCCTGTAGAGGAAGAGGAAGAATTGCAGTCACAACAGCTACTCCCACAACAGCTGCCTGAATG CAAAGTTGATAGTGAAACCAACATAGAAGCTAGTAAGCTACCTACATCTGAACCAGAAGCTGACGCTGAAATAGAGCCCAAAGAGAGCAA CGGCACAAAACTAGAAGAACCTATTAATGAAGAAACACCATCCCAAGATGAAGAGGAGGGTGTGTCTGATGTGGAGAGTGAAAGGAGCCA AGAACAGCCAGATAAAACAGTGGATATAAGTGATTTGGCCACCAAACTCCTGGACAGTTGGAAAGACCTAAAGGAGATAAATGGCATCAC CGCGGCACTGGCTGAAGAGCTCTTTGAGAAAGGAGAACAGCTCCTGGGGGCCGGCGAGGTCTTTGCCATTGGACCCCTGCAGCTGTATGC CGTCACGGAGCAGCTGCAGCAGGGAAAGCCCACGTGCGCCAGTGGGGATGCCAAGACCGACCTCGGGCACATCCTGGACTTCACCTGTCG CCTTAAGTACCTTAAGGTTTCTGGCACAGAAGGACCTTTTGGGACCAGCAACATTCAGGAGCAGCTCCTGCCGTTCGACCTATCAATATT CAAGTCCCTGCATCAGGTGGAGATAAGTCACTGTGATGCTAAGCACATCAGAGGGCTGGTCGCATCGAAGCCCACCTTAGCCACGCTGAG TGTCCGCTTCTCAGCAACCTCGATGAAGGAAGTCCTTGTTCCTGAAGCCTCAGAATTTGATGAGTGGGAGCCTGAAGGCACAACCCTAGA AGGCCCTGTGACTGCCGTCATCCCCACTTGGCAGGCATTGACCACGCTTGACCTGAGCCACAACAGCGTCTCCGAGATCGACGAGTCTGT GAAACTGATCCCAAAGATTGAGTTCCTGGACCTGAGTCACAATGGATTGCTGGTTGTGGACAATCTGCAGCACCTGTATAACCTTGTGCA TCTGGACCTGTCCTACAACAAGCTCTCCTCCTTGGAAGGGCTTCACACCAAGCTGGGGAACATCAAGACCTTAAACCTGGCAGGCAACCT CCTAGAGAGTCTGAGTGGCCTGCACAAGCTCTACTCACTGGTCAACCTGGATCTCCGGGACAACAGGATCGAACAGATGGAGGAGGTCCG GAGCATAGGCAGCCTCCCGTGTCTGGAGCACGTGTCTCTGCTGAACAACCCTCTGAGCATCATCCCCGACTACCGGACCAAGGTGCTGGC TCAGTTCGGAGAGAGGGCCTCAGAGGTCTGTCTGGATGACACAGTGACCACAGAGAAGGAGCTGGACACTGTGGAAGTGCTGAAAGCAAT TCAGAAAGCCAAGGAGGTCAAGTCCAAACTGAGCAACCCAGAGAAGAAGGGTGGTGAAGACTCCCGGCTCTCAGCTGCCCCCTGCATCAG ACCCAGCAGCTCCCCTCCCACTGTGGCTCCCGCATCTGCCTCCCTGCCCCAGCCCATCCTCTCTAACCAAGGTAATCGTGTATGTATCTT GCTTCTAGTGGAGCCACACAGCCCTGCCTGGGCCCCCTGGCTGGGCTGGGGTTGGGGGAGAGGTGCCAGCACCTGCTTCCAACAGGGTCA GACACAGGGAGGGCAGTGCCTTCTGCAGGCTGGTCCTCGCGGGGGGACACATGGCAGGGGTGCCTGGCCTGATGCCAGCTGTTGCTTGCT TGGTGAGGACTCCCAATTGCTCTGATGCCCACATCCAGCTCCTCTAGGAGACCGCAGGGTGTCTGACAGGCCCTGAGGCTGCCCTCTGAA CAGGCTCGGGGCTGTTGGCTCATGGGACCCATTCCCTCACCGGCAGCACAAGCAGGTTGGCTCCTGGTTACAGGAAGCCGGGCTTGTGAC TTTACTGTCTGGAGCCCGAATCCCTGTGCAGGGAAAAGCTTGCTTTTATCACTGCCTCATCTCTGTGGGGTGACCCAGCCCCAGAACACC ATGTTTGTGGGGCCAAGATGGGCCATCTCTGTCCCTGTGGACCCATGGAAGACCAGGCCCATTCGTCTGCCCACTATCTTAGCGTTTTCA AAGGGCTTTCACCTCTGAACCCAGGCATCCTCGGAGATGAGTGAGTGAAGCAGGTCTCATGAGCGTGTCTGCTGGCCCGGCCCCCACGGA AGAGGGGAGGGTGTGCCGTCCCGAGTGGAGCCGAGGCTCGGGACACGCAGGAAAGGACGCCGCCTGCCCGGGCTCCTGGAGACGCAGAAC TTGGTGTGAGGTCTTGGGAAAACAGTTCAACCCGATGTTTTAAGAGCCAGAAAAACATTCCCACCCCTTGACCTGGTAACCCCACTGGTG GGGATTTTCTCTTAGAGGGATAAGATACCGGGAAGGGGAGGTGAAATGCTCACCACTGCCAAAACACGGGCTGCAACTGCAACATCGGAG GATGAGAGGGAGAGTCGGCTGTGGTGCAGAATGCTCAGCAGCCCTCCCAGCAGGGACAGGAAGACTGGGCAGGAAGAGGGGAGAAGCATT CAAGTTAAGGCAAAAGGCCCAACGCAGAGCAGCACACTGAGGTCACACCTGTGAGATGTGGAAGAGAATTCCTGAGCGTGGAGCGATGGG GTTAGGTGCCAGGATGATTGCCCATTTTGCTTCTGTCAGACTCTTGACTAAGGATTTCTGGTTGCATTTTATTACATAAAAGCCAGGGAG GTTATATCACGGTGAGAAAGCTTCCCTGACGCTGCCTCCTGTAGCGCAGCCAAGCGAGCCTGTGGAGGTACCATATGACTGTAGGCCTCT GGGGACAGGGAGCTGCATCTGCTTCTCAAGGCCAGGGACACAGCCATTTCTGCCAGCATCTGTTGATCAGTGAGTGAGTGAGTGGGCAGG TAGAGCAGGAGCCAGTGAAGAGCAGGCCCTGGATGGGTGGGGATGCACCATGTCCCCAGGCTGCAGCTGCAGGCAGCCCCCCACATTGTC GGAGAAGCCTCTGCACCAGCTCAGCCCCCTCCTCACTCCCCTTGTGCCCTGGGGACACTCTGCAGAGGGGCACTCTGCAGTCTGTCCCCG >80877_80877_4_SETD2-NISCH_SETD2_chr3_47125210_ENST00000409792_NISCH_chr3_52504875_ENST00000488380_length(amino acids)=2497AA_BP=2032 LRGGGSRRRLQPLPMKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFS FSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASP PTHAAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKEPPIIIVPESLEADTKQ DTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIE KERDFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYSRSERSHYYDSDRRYHR SSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEA IKRCCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINKNPEREKAGSPA PSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSE LSPLVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIYCT LNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSL PPGIKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQEAQEEGNSILPERRGR PEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRL QSVVVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKNPEISFTQSSRKQIDNR LPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHV DGLHSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVYDRTQGQVPDSLTDDRE EEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKK VRVEVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIAC GEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYF MALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVS IRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAEL GDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKL MFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESN GTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYA VTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATLS VRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSVSEIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVH LDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLA QFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLSAAPCIRPSSSPPTVAPASASLPQPILSNQGNRVCIL -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SETD2-NISCH |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 1418_1714 | 2020.0 | 2565.0 | TUBA1A |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 709_807 | 120.0 | 1505.0 | ITGA5 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 709_807 | 120.0 | 516.0 | ITGA5 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 709_807 | 120.0 | 1505.0 | ITGA5 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 660_869 | 120.0 | 1505.0 | LIMK | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 660_869 | 120.0 | 516.0 | LIMK | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 660_869 | 120.0 | 1505.0 | LIMK | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000345716 | 2 | 21 | 245_869 | 120.0 | 1505.0 | PAK1 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000420808 | 2 | 14 | 245_869 | 120.0 | 516.0 | PAK1 | |
| Tgene | NISCH | chr3:47125210 | chr3:52504875 | ENST00000479054 | 3 | 22 | 245_869 | 120.0 | 1505.0 | PAK1 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | SETD2 | chr3:47125210 | chr3:52504875 | ENST00000409792 | - | 12 | 21 | 2457_2564 | 2020.0 | 2565.0 | POLR2A |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SETD2-NISCH |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SETD2-NISCH |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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