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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SETD5-LMCD1 (FusionGDB2 ID:80910)

Fusion Gene Summary for SETD5-LMCD1

check button Fusion gene summary
Fusion gene informationFusion gene name: SETD5-LMCD1
Fusion gene ID: 80910
HgeneTgene
Gene symbol

SETD5

LMCD1

Gene ID

55209

29995

Gene nameSET domain containing 5LIM and cysteine rich domains 1
Synonyms--
Cytomap

3p25.3

3p25.3

Type of geneprotein-codingprotein-coding
Descriptionhistone-lysine N-methyltransferase SETD5SET domain-containing protein 5LIM and cysteine-rich domains protein 1dyxin
Modification date2020031320200313
UniProtAcc.

Q9NZU5

Ensembl transtripts involved in fusion geneENST00000302463, ENST00000402198, 
ENST00000402466, ENST00000406341, 
ENST00000407969, ENST00000488236, 
ENST00000397386, ENST00000454244, 
ENST00000157600, ENST00000535732, 
Fusion gene scores* DoF score19 X 16 X 7=21284 X 2 X 3=24
# samples 234
** MAII scorelog2(23/2128*10)=-3.20979238455681
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: SETD5 [Title/Abstract] AND LMCD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSETD5(9483929)-LMCD1(8574423), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SETD5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LMCD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-LL-A8F5-01ASETD5chr3

9483929

-LMCD1chr3

8574423

+
ChimerDB4BRCATCGA-LL-A8F5-01ASETD5chr3

9483929

+LMCD1chr3

8574423

+


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Fusion Gene ORF analysis for SETD5-LMCD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000302463ENST00000397386SETD5chr3

9483929

+LMCD1chr3

8574423

+
5CDS-5UTRENST00000402198ENST00000397386SETD5chr3

9483929

+LMCD1chr3

8574423

+
5CDS-5UTRENST00000402466ENST00000397386SETD5chr3

9483929

+LMCD1chr3

8574423

+
5CDS-5UTRENST00000406341ENST00000397386SETD5chr3

9483929

+LMCD1chr3

8574423

+
5CDS-5UTRENST00000407969ENST00000397386SETD5chr3

9483929

+LMCD1chr3

8574423

+
5CDS-intronENST00000302463ENST00000454244SETD5chr3

9483929

+LMCD1chr3

8574423

+
5CDS-intronENST00000402198ENST00000454244SETD5chr3

9483929

+LMCD1chr3

8574423

+
5CDS-intronENST00000402466ENST00000454244SETD5chr3

9483929

+LMCD1chr3

8574423

+
5CDS-intronENST00000406341ENST00000454244SETD5chr3

9483929

+LMCD1chr3

8574423

+
5CDS-intronENST00000407969ENST00000454244SETD5chr3

9483929

+LMCD1chr3

8574423

+
In-frameENST00000302463ENST00000157600SETD5chr3

9483929

+LMCD1chr3

8574423

+
In-frameENST00000302463ENST00000535732SETD5chr3

9483929

+LMCD1chr3

8574423

+
In-frameENST00000402198ENST00000157600SETD5chr3

9483929

+LMCD1chr3

8574423

+
In-frameENST00000402198ENST00000535732SETD5chr3

9483929

+LMCD1chr3

8574423

+
In-frameENST00000402466ENST00000157600SETD5chr3

9483929

+LMCD1chr3

8574423

+
In-frameENST00000402466ENST00000535732SETD5chr3

9483929

+LMCD1chr3

8574423

+
In-frameENST00000406341ENST00000157600SETD5chr3

9483929

+LMCD1chr3

8574423

+
In-frameENST00000406341ENST00000535732SETD5chr3

9483929

+LMCD1chr3

8574423

+
In-frameENST00000407969ENST00000157600SETD5chr3

9483929

+LMCD1chr3

8574423

+
In-frameENST00000407969ENST00000535732SETD5chr3

9483929

+LMCD1chr3

8574423

+
intron-3CDSENST00000488236ENST00000157600SETD5chr3

9483929

+LMCD1chr3

8574423

+
intron-3CDSENST00000488236ENST00000535732SETD5chr3

9483929

+LMCD1chr3

8574423

+
intron-5UTRENST00000488236ENST00000397386SETD5chr3

9483929

+LMCD1chr3

8574423

+
intron-intronENST00000488236ENST00000454244SETD5chr3

9483929

+LMCD1chr3

8574423

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000402198SETD5chr39483929+ENST00000157600LMCD1chr38574423+308915124262567713
ENST00000402198SETD5chr39483929+ENST00000535732LMCD1chr38574423+221415124262213595
ENST00000402466SETD5chr39483929+ENST00000157600LMCD1chr38574423+312815514262606726
ENST00000402466SETD5chr39483929+ENST00000535732LMCD1chr38574423+225315514262252608
ENST00000406341SETD5chr39483929+ENST00000157600LMCD1chr38574423+284412671812322713
ENST00000406341SETD5chr39483929+ENST00000535732LMCD1chr38574423+196912671811968596
ENST00000407969SETD5chr39483929+ENST00000157600LMCD1chr38574423+2725114852203732
ENST00000407969SETD5chr39483929+ENST00000535732LMCD1chr38574423+1850114851849615
ENST00000302463SETD5chr39483929+ENST00000157600LMCD1chr38574423+272411471962202668
ENST00000302463SETD5chr39483929+ENST00000535732LMCD1chr38574423+184911471961848551

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000402198ENST00000157600SETD5chr39483929+LMCD1chr38574423+0.0022627260.9977373
ENST00000402198ENST00000535732SETD5chr39483929+LMCD1chr38574423+0.0042561950.9957438
ENST00000402466ENST00000157600SETD5chr39483929+LMCD1chr38574423+0.0031319920.99686795
ENST00000402466ENST00000535732SETD5chr39483929+LMCD1chr38574423+0.0052100030.99478996
ENST00000406341ENST00000157600SETD5chr39483929+LMCD1chr38574423+0.0019949710.9980051
ENST00000406341ENST00000535732SETD5chr39483929+LMCD1chr38574423+0.0036843260.99631566
ENST00000407969ENST00000157600SETD5chr39483929+LMCD1chr38574423+0.0028496670.99715036
ENST00000407969ENST00000535732SETD5chr39483929+LMCD1chr38574423+0.0037891760.9962108
ENST00000302463ENST00000157600SETD5chr39483929+LMCD1chr38574423+0.0050269990.99497294
ENST00000302463ENST00000535732SETD5chr39483929+LMCD1chr38574423+0.0039011180.9960989

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Fusion Genomic Features for SETD5-LMCD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SETD5chr39483929+LMCD1chr38574422+0.152571290.84742874
SETD5chr39483929+LMCD1chr38574422+0.152571290.84742874

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SETD5-LMCD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:9483929/chr3:8574423)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.LMCD1

Q9NZU5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway. {ECO:0000250, ECO:0000269|PubMed:20026769}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLMCD1chr3:9483929chr3:8574423ENST000001576000628_5814366.0Compositional biasNote=Cys-rich
TgeneLMCD1chr3:9483929chr3:8574423ENST0000015760006241_30614366.0DomainLIM zinc-binding 1
TgeneLMCD1chr3:9483929chr3:8574423ENST0000015760006307_36514366.0DomainLIM zinc-binding 2
TgeneLMCD1chr3:9483929chr3:8574423ENST000001576000699_20614366.0DomainPET

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSETD5chr3:9483929chr3:8574423ENST00000302463+9221089_14112611345.0Compositional biasNote=Ser-rich
HgeneSETD5chr3:9483929chr3:8574423ENST00000402198+10231089_14113591443.0Compositional biasNote=Ser-rich
HgeneSETD5chr3:9483929chr3:8574423ENST00000402466+11241089_14112611345.0Compositional biasNote=Ser-rich
HgeneSETD5chr3:9483929chr3:8574423ENST00000406341+9221089_14113591443.0Compositional biasNote=Ser-rich
HgeneSETD5chr3:9483929chr3:8574423ENST00000302463+922269_3902611345.0DomainSET
HgeneSETD5chr3:9483929chr3:8574423ENST00000402198+1023269_3903591443.0DomainSET
HgeneSETD5chr3:9483929chr3:8574423ENST00000402466+1124269_3902611345.0DomainSET
HgeneSETD5chr3:9483929chr3:8574423ENST00000406341+922269_3903591443.0DomainSET


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Fusion Gene Sequence for SETD5-LMCD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80910_80910_1_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000302463_LMCD1_chr3_8574423_ENST00000157600_length(transcript)=2724nt_BP=1147nt
GGCAGTACCAGGGATTAGGGTCTGGGCTGGAAAAATCCTGGTGTTTTGAATATGTTCAGGTCCAGTTCAGACTCTTGATCCCACAGCCAC
TTCTTGAGTGAGCCCTGAATCTGTGGAGGCTAGTCCAGCAGTTAATGAGAAGAGCGTGTATTCCACTCATAATTATGGGACCACTCAGAG
GCATGGGTGTCGAGGACTGCCTTATGCTACGATCATCCCTCGTTCTGACCTGAATGGCCTGCCGTCGCCTGTAGAGGAACGCTGTGGAGA
CAGCCCGAACTCTGAAGGAGAAACTGTACCTACCTGGTGTCCTTGTGGTCTTTCTCAGGATGGCTTCCTTCTCAACTGTGACAAGTGCAG
GGGAATGAGCAGGGGGAAGGTTATTAGACTTCATCGGCGGAAGCAGGACAACATATCAGGTGGGGATAGCAGTGCAACAGAAAGCTGGGA
TGAGGAGCTTTCTCCTTCCACTGTGTTGTATACAGCAACACAGCACACACCTACAAGCATCACCTTAACTGTTAGAAGAACCAAACCCAA
GAAGCGGAAAAAGAGTCCAGAAAAGGGTCGTGCAGCACCAAAGACGAAGAAAATCAAGGCATTTCGAGAGGGATCCCGGAAGTCCTTGCG
GATGAAGAATTCTCCCTCTGAAGCACAGAATTTAGATGAGAATACAACTGAGGGCTGGGAAAATCGGATAAGACTATGGACTGACCAGTA
TGAAGAAGCTTTCACTAATCAGTACAGTGCAGATGTACAGAACGCGCTTGAACAACACCTACATTCTAGCAAGGAATTTGTGGGCAAACC
TACTATTTTAGACACTATTAATAAGACTGAATTGGCCTGTAATAACACAGTTATTGGTTCCCAAATGCAGTTACAGCTGGGAAGAGTCAC
TCGTGTTCAAAAGCACCGGAAGATCCTGAGGGCTGCAAGAGATTTGGCTTTGGACACTCTTATAATAGAGTATCGTGGGAAAGTCATGTT
ACGACAGCAATTTGAGGTCAATGGGCATTTCTTCAAAAAACCATACCCCTTTGTGCTCTTCTACTCAAAATTCAATGGTGTAGAGATGTG
TGTGGATGCCCGTACTTTCGGTAATGATGCTCGGTTCATCAGAAGATCATGTACACCAAATGCAGAGATGTCCCTGGGCCAGCTGCAGTC
AGCAAGAGGTGTGGCATGTTTGGGATGCAAGGGGACGTGTTCGGGCTTCGAGCCACATTCATGGAGGAAAATATGCAAGTCTTGCAAATG
CAGCCAAGAGGACCACTGCCTAACATCTGACCTAGAAGACGATCGGAAAATTGGCCGCTTGCTGATGGACTCCAAGTATTCCACCCTCAC
TGCTCGGGTGAAAGGCGGGGACGGCATCCGGATTTACAAGAGGAACCGGATGATCATGACCAACCCTATTGCTACTGGGAAAGATCCCAC
TTTTGACACCATCACCTACGAGTGGGCTCCCCCTGGAGTCACCCAGAAACTGGGACTGCAGTACATGGAGCTCATCCCCAAGGAGAAGCA
GCCAGTGACAGGCACAGAGGGTGCCTTTTACCGCCGCCGCCAGCTCATGCACCAGCTCCCCATCTATGACCAGGATCCCTCGCGCTGCCG
TGGACTTTTGGAGAATGAGTTGAAACTGATGGAAGAATTTGTCAAGCAATATAAGAGCGAGGCCCTCGGCGTGGGAGAAGTGGCCCTCCC
GGGGCAGGGTGGCTTGCCCAAGGAGGAGGGGAAGCAGCAGGAAAAGCCAGAGGGGGCAGAGACCACTGCTGCTACCACCAACGGCAGTCT
CAGTGACCCGTCCAAAGAAGTGGAATACGTCTGCGAGCTCTGCAAGGGAGCGGCCCCTCCTGACAGCCCCGTGGTCTACTCGGACAGGGC
AGGCTACAACAAGCAGTGGCACCCCACCTGCTTTGTGTGTGCCAAGTGCTCCGAGCCGCTGGTGGACCTCATCTACTTCTGGAAGGATGG
TGCACCCTGGTGCGGCCGCCATTACTGCGAGAGTCTGCGGCCCCGGTGCTCCGGCTGCGATGAGATAATATTCGCTGAGGACTACCAGCG
TGTGGAAGATCTGGCCTGGCACCGAAAGCACTTTGTCTGTGAGGGTTGTGAGCAGCTGCTGAGCGGCCGGGCGTACATCGTCACCAAGGG
TCAGCTTCTGTGCCCAACTTGCAGCAAGTCCAAACGCTCCTGAAGGGCTGCCCACCCACAGCCAGAATCCACAGGATCCCACCGAGAAGG
AGAGCCAGGTGTGCCGAGACCATCCTAAGGGTCCGATGTGACAGCAAGCAAGTGAAATAAACAATGATTTGCTTTTCAGTGAGAATATAT
ATATGAGATATATATAGATATATATTCTAGGTTGGGTGGTGGTAGATCCTTGAGGGTCAGTAGTTTCAAAACCAAAAATATTCTAAGAAG
TCTTAGGATGGAGTTCCTTTTCTTTCTGTTGTTGTTTCCCAGCTACAACCAACTAAAGACACAAATGGCGTTCTGCAAGGGGACTCTGGG
AGGAGTTTTCCAGAATGCAATTCCGAGTGAGCAAATCGCATAGCTGTAGAATGTGCGTGCTTTTTTGTGGACACAGGAGCTCCTCCAGGA
GCAGGCTGGGATCCCAACTATCGCTTGTTGCCTCTTTTTCAAGTGGAATTTGAATTTTAAATAAACAACTTTTTTTGGCATGATAAACAG

>80910_80910_1_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000302463_LMCD1_chr3_8574423_ENST00000157600_length(amino acids)=668AA_BP=317
MPYATIIPRSDLNGLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSP
STVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKAFREGSRKSLRMKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFT
NQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFE
VNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDH
CLTSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGT
EGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSK
EVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLA

--------------------------------------------------------------
>80910_80910_2_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000302463_LMCD1_chr3_8574423_ENST00000535732_length(transcript)=1849nt_BP=1147nt
GGCAGTACCAGGGATTAGGGTCTGGGCTGGAAAAATCCTGGTGTTTTGAATATGTTCAGGTCCAGTTCAGACTCTTGATCCCACAGCCAC
TTCTTGAGTGAGCCCTGAATCTGTGGAGGCTAGTCCAGCAGTTAATGAGAAGAGCGTGTATTCCACTCATAATTATGGGACCACTCAGAG
GCATGGGTGTCGAGGACTGCCTTATGCTACGATCATCCCTCGTTCTGACCTGAATGGCCTGCCGTCGCCTGTAGAGGAACGCTGTGGAGA
CAGCCCGAACTCTGAAGGAGAAACTGTACCTACCTGGTGTCCTTGTGGTCTTTCTCAGGATGGCTTCCTTCTCAACTGTGACAAGTGCAG
GGGAATGAGCAGGGGGAAGGTTATTAGACTTCATCGGCGGAAGCAGGACAACATATCAGGTGGGGATAGCAGTGCAACAGAAAGCTGGGA
TGAGGAGCTTTCTCCTTCCACTGTGTTGTATACAGCAACACAGCACACACCTACAAGCATCACCTTAACTGTTAGAAGAACCAAACCCAA
GAAGCGGAAAAAGAGTCCAGAAAAGGGTCGTGCAGCACCAAAGACGAAGAAAATCAAGGCATTTCGAGAGGGATCCCGGAAGTCCTTGCG
GATGAAGAATTCTCCCTCTGAAGCACAGAATTTAGATGAGAATACAACTGAGGGCTGGGAAAATCGGATAAGACTATGGACTGACCAGTA
TGAAGAAGCTTTCACTAATCAGTACAGTGCAGATGTACAGAACGCGCTTGAACAACACCTACATTCTAGCAAGGAATTTGTGGGCAAACC
TACTATTTTAGACACTATTAATAAGACTGAATTGGCCTGTAATAACACAGTTATTGGTTCCCAAATGCAGTTACAGCTGGGAAGAGTCAC
TCGTGTTCAAAAGCACCGGAAGATCCTGAGGGCTGCAAGAGATTTGGCTTTGGACACTCTTATAATAGAGTATCGTGGGAAAGTCATGTT
ACGACAGCAATTTGAGGTCAATGGGCATTTCTTCAAAAAACCATACCCCTTTGTGCTCTTCTACTCAAAATTCAATGGTGTAGAGATGTG
TGTGGATGCCCGTACTTTCGGTAATGATGCTCGGTTCATCAGAAGATCATGTACACCAAATGCAGAGATGTCCCTGGGCCAGCTGCAGTC
AGCAAGAGGTGTGGCATGTTTGGGATGCAAGGGGACGTGTTCGGGCTTCGAGCCACATTCATGGAGGAAAATATGCAAGTCTTGCAAATG
CAGCCAAGAGGACCACTGCCTAACATCTGACCTAGAAGACGATCGGAAAATTGGCCGCTTGCTGATGGACTCCAAGTATTCCACCCTCAC
TGCTCGGGTGAAAGGCGGGGACGGCATCCGGATTTACAAGAGGAACCGGATGATCATGACCAACCCTATTGCTACTGGGAAAGATCCCAC
TTTTGACACCATCACCTACGAGTGGGCTCCCCCTGGAGTCACCCAGAAACTGGGACTGCAGTACATGGAGCTCATCCCCAAGGAGAAGCA
GCCAGTGACAGGCACAGAGGGTGCCTTTTACCGCCGCCGCCAGCTCATGCACCAGCTCCCCATCTATGACCAGGATCCCTCGCGCTGCCG
TGGACTTTTGGAGAATGAGTTGAAACTGATGGAAGAATTTGTCAAGCAATATAAGAGCGAGGCCCTCGGCGTGGGAGAAGTGGCCCTCCC
GGGGCAGGGTGGCTTGCCCAAGGAGGAGGGGAAGCAGCAGGAAAAGCCAGAGGGGGCAGAGACCACTGCTGCTACCACCAACGGCAGTCT

>80910_80910_2_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000302463_LMCD1_chr3_8574423_ENST00000535732_length(amino acids)=551AA_BP=317
MPYATIIPRSDLNGLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSP
STVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKAFREGSRKSLRMKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFT
NQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFE
VNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDH
CLTSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGT
EGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSK

--------------------------------------------------------------
>80910_80910_3_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000402198_LMCD1_chr3_8574423_ENST00000157600_length(transcript)=3089nt_BP=1512nt
GCTCAGAGACTCACGCAGCCCCAGTCCCGCCAGTCCGCCAACACAGTAGTGCCGGCCCCCCTCTTTCCCTGGCCCTGCCCCCCCTCCCCG
CCTTTGGCTCGCTCCGCCTTTCTGCCCCCCACCCCCACCTCACGGGTACGGGCCATTCCCGGCCAGGAAACGCCGTGGCGCCGCGTTGGG
CCTAACTCGAGTCCTGCCGCCTCCCGGGAGTGCCGTGCGCCGCAGCCCGGGCCCAGGCCCCGGCAGCGCCTGGGACAAGGTCTTCAGAAC
TACTAGCAGATAATTTGGGGGGACTTCATATTCAGAAGTCTATATAAAGGATTCCTCATGTCCATAACATGTTGGATGAGGCTCTGCAGC
TCACCCCCACTCTCAGAGTGGTCAGTCTCCATTAATTGGACCCCGTGATTTCCAATCTCTGCTGTGTTGGACGTCATGAGCATTGCAATC
CCTCTGGGAGTCACCACATCAGATACATCCTACTCAGATATGGCTGCTGGATCAGACCCTGAATCTGTGGAGGCTAGTCCAGCAGTTAAT
GAGAAGAGCGTGTATTCCACTCATAATTATGGGACCACTCAGAGGCATGGGTGTCGAGGACTGCCTTATGCTACGATCATCCCTCGTTCT
GACCTGAATGGCCTGCCGTCGCCTGTAGAGGAACGCTGTGGAGACAGCCCGAACTCTGAAGGAGAAACTGTACCTACCTGGTGTCCTTGT
GGTCTTTCTCAGGATGGCTTCCTTCTCAACTGTGACAAGTGCAGGGGAATGAGCAGGGGGAAGGTTATTAGACTTCATCGGCGGAAGCAG
GACAACATATCAGGTGGGGATAGCAGTGCAACAGAAAGCTGGGATGAGGAGCTTTCTCCTTCCACTGTGTTGTATACAGCAACACAGCAC
ACACCTACAAGCATCACCTTAACTGTTAGAAGAACCAAACCCAAGAAGCGGAAAAAGAGTCCAGAAAAGGGTCGTGCAGCACCAAAGACG
AAGAAAATCAAGAATTCTCCCTCTGAAGCACAGAATTTAGATGAGAATACAACTGAGGGCTGGGAAAATCGGATAAGACTATGGACTGAC
CAGTATGAAGAAGCTTTCACTAATCAGTACAGTGCAGATGTACAGAACGCGCTTGAACAACACCTACATTCTAGCAAGGAATTTGTGGGC
AAACCTACTATTTTAGACACTATTAATAAGACTGAATTGGCCTGTAATAACACAGTTATTGGTTCCCAAATGCAGTTACAGCTGGGAAGA
GTCACTCGTGTTCAAAAGCACCGGAAGATCCTGAGGGCTGCAAGAGATTTGGCTTTGGACACTCTTATAATAGAGTATCGTGGGAAAGTC
ATGTTACGACAGCAATTTGAGGTCAATGGGCATTTCTTCAAAAAACCATACCCCTTTGTGCTCTTCTACTCAAAATTCAATGGTGTAGAG
ATGTGTGTGGATGCCCGTACTTTCGGTAATGATGCTCGGTTCATCAGAAGATCATGTACACCAAATGCAGAGATGTCCCTGGGCCAGCTG
CAGTCAGCAAGAGGTGTGGCATGTTTGGGATGCAAGGGGACGTGTTCGGGCTTCGAGCCACATTCATGGAGGAAAATATGCAAGTCTTGC
AAATGCAGCCAAGAGGACCACTGCCTAACATCTGACCTAGAAGACGATCGGAAAATTGGCCGCTTGCTGATGGACTCCAAGTATTCCACC
CTCACTGCTCGGGTGAAAGGCGGGGACGGCATCCGGATTTACAAGAGGAACCGGATGATCATGACCAACCCTATTGCTACTGGGAAAGAT
CCCACTTTTGACACCATCACCTACGAGTGGGCTCCCCCTGGAGTCACCCAGAAACTGGGACTGCAGTACATGGAGCTCATCCCCAAGGAG
AAGCAGCCAGTGACAGGCACAGAGGGTGCCTTTTACCGCCGCCGCCAGCTCATGCACCAGCTCCCCATCTATGACCAGGATCCCTCGCGC
TGCCGTGGACTTTTGGAGAATGAGTTGAAACTGATGGAAGAATTTGTCAAGCAATATAAGAGCGAGGCCCTCGGCGTGGGAGAAGTGGCC
CTCCCGGGGCAGGGTGGCTTGCCCAAGGAGGAGGGGAAGCAGCAGGAAAAGCCAGAGGGGGCAGAGACCACTGCTGCTACCACCAACGGC
AGTCTCAGTGACCCGTCCAAAGAAGTGGAATACGTCTGCGAGCTCTGCAAGGGAGCGGCCCCTCCTGACAGCCCCGTGGTCTACTCGGAC
AGGGCAGGCTACAACAAGCAGTGGCACCCCACCTGCTTTGTGTGTGCCAAGTGCTCCGAGCCGCTGGTGGACCTCATCTACTTCTGGAAG
GATGGTGCACCCTGGTGCGGCCGCCATTACTGCGAGAGTCTGCGGCCCCGGTGCTCCGGCTGCGATGAGATAATATTCGCTGAGGACTAC
CAGCGTGTGGAAGATCTGGCCTGGCACCGAAAGCACTTTGTCTGTGAGGGTTGTGAGCAGCTGCTGAGCGGCCGGGCGTACATCGTCACC
AAGGGTCAGCTTCTGTGCCCAACTTGCAGCAAGTCCAAACGCTCCTGAAGGGCTGCCCACCCACAGCCAGAATCCACAGGATCCCACCGA
GAAGGAGAGCCAGGTGTGCCGAGACCATCCTAAGGGTCCGATGTGACAGCAAGCAAGTGAAATAAACAATGATTTGCTTTTCAGTGAGAA
TATATATATGAGATATATATAGATATATATTCTAGGTTGGGTGGTGGTAGATCCTTGAGGGTCAGTAGTTTCAAAACCAAAAATATTCTA
AGAAGTCTTAGGATGGAGTTCCTTTTCTTTCTGTTGTTGTTTCCCAGCTACAACCAACTAAAGACACAAATGGCGTTCTGCAAGGGGACT
CTGGGAGGAGTTTTCCAGAATGCAATTCCGAGTGAGCAAATCGCATAGCTGTAGAATGTGCGTGCTTTTTTGTGGACACAGGAGCTCCTC
CAGGAGCAGGCTGGGATCCCAACTATCGCTTGTTGCCTCTTTTTCAAGTGGAATTTGAATTTTAAATAAACAACTTTTTTTGGCATGATA

>80910_80910_3_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000402198_LMCD1_chr3_8574423_ENST00000157600_length(amino acids)=713AA_BP=362
MDVMSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYATIIPRSDLNGLPSPVEERCGDSPNSEGE
TVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPE
KGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGS
QMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPN
AEMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMT
NPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSE
ALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPL

--------------------------------------------------------------
>80910_80910_4_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000402198_LMCD1_chr3_8574423_ENST00000535732_length(transcript)=2214nt_BP=1512nt
GCTCAGAGACTCACGCAGCCCCAGTCCCGCCAGTCCGCCAACACAGTAGTGCCGGCCCCCCTCTTTCCCTGGCCCTGCCCCCCCTCCCCG
CCTTTGGCTCGCTCCGCCTTTCTGCCCCCCACCCCCACCTCACGGGTACGGGCCATTCCCGGCCAGGAAACGCCGTGGCGCCGCGTTGGG
CCTAACTCGAGTCCTGCCGCCTCCCGGGAGTGCCGTGCGCCGCAGCCCGGGCCCAGGCCCCGGCAGCGCCTGGGACAAGGTCTTCAGAAC
TACTAGCAGATAATTTGGGGGGACTTCATATTCAGAAGTCTATATAAAGGATTCCTCATGTCCATAACATGTTGGATGAGGCTCTGCAGC
TCACCCCCACTCTCAGAGTGGTCAGTCTCCATTAATTGGACCCCGTGATTTCCAATCTCTGCTGTGTTGGACGTCATGAGCATTGCAATC
CCTCTGGGAGTCACCACATCAGATACATCCTACTCAGATATGGCTGCTGGATCAGACCCTGAATCTGTGGAGGCTAGTCCAGCAGTTAAT
GAGAAGAGCGTGTATTCCACTCATAATTATGGGACCACTCAGAGGCATGGGTGTCGAGGACTGCCTTATGCTACGATCATCCCTCGTTCT
GACCTGAATGGCCTGCCGTCGCCTGTAGAGGAACGCTGTGGAGACAGCCCGAACTCTGAAGGAGAAACTGTACCTACCTGGTGTCCTTGT
GGTCTTTCTCAGGATGGCTTCCTTCTCAACTGTGACAAGTGCAGGGGAATGAGCAGGGGGAAGGTTATTAGACTTCATCGGCGGAAGCAG
GACAACATATCAGGTGGGGATAGCAGTGCAACAGAAAGCTGGGATGAGGAGCTTTCTCCTTCCACTGTGTTGTATACAGCAACACAGCAC
ACACCTACAAGCATCACCTTAACTGTTAGAAGAACCAAACCCAAGAAGCGGAAAAAGAGTCCAGAAAAGGGTCGTGCAGCACCAAAGACG
AAGAAAATCAAGAATTCTCCCTCTGAAGCACAGAATTTAGATGAGAATACAACTGAGGGCTGGGAAAATCGGATAAGACTATGGACTGAC
CAGTATGAAGAAGCTTTCACTAATCAGTACAGTGCAGATGTACAGAACGCGCTTGAACAACACCTACATTCTAGCAAGGAATTTGTGGGC
AAACCTACTATTTTAGACACTATTAATAAGACTGAATTGGCCTGTAATAACACAGTTATTGGTTCCCAAATGCAGTTACAGCTGGGAAGA
GTCACTCGTGTTCAAAAGCACCGGAAGATCCTGAGGGCTGCAAGAGATTTGGCTTTGGACACTCTTATAATAGAGTATCGTGGGAAAGTC
ATGTTACGACAGCAATTTGAGGTCAATGGGCATTTCTTCAAAAAACCATACCCCTTTGTGCTCTTCTACTCAAAATTCAATGGTGTAGAG
ATGTGTGTGGATGCCCGTACTTTCGGTAATGATGCTCGGTTCATCAGAAGATCATGTACACCAAATGCAGAGATGTCCCTGGGCCAGCTG
CAGTCAGCAAGAGGTGTGGCATGTTTGGGATGCAAGGGGACGTGTTCGGGCTTCGAGCCACATTCATGGAGGAAAATATGCAAGTCTTGC
AAATGCAGCCAAGAGGACCACTGCCTAACATCTGACCTAGAAGACGATCGGAAAATTGGCCGCTTGCTGATGGACTCCAAGTATTCCACC
CTCACTGCTCGGGTGAAAGGCGGGGACGGCATCCGGATTTACAAGAGGAACCGGATGATCATGACCAACCCTATTGCTACTGGGAAAGAT
CCCACTTTTGACACCATCACCTACGAGTGGGCTCCCCCTGGAGTCACCCAGAAACTGGGACTGCAGTACATGGAGCTCATCCCCAAGGAG
AAGCAGCCAGTGACAGGCACAGAGGGTGCCTTTTACCGCCGCCGCCAGCTCATGCACCAGCTCCCCATCTATGACCAGGATCCCTCGCGC
TGCCGTGGACTTTTGGAGAATGAGTTGAAACTGATGGAAGAATTTGTCAAGCAATATAAGAGCGAGGCCCTCGGCGTGGGAGAAGTGGCC
CTCCCGGGGCAGGGTGGCTTGCCCAAGGAGGAGGGGAAGCAGCAGGAAAAGCCAGAGGGGGCAGAGACCACTGCTGCTACCACCAACGGC

>80910_80910_4_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000402198_LMCD1_chr3_8574423_ENST00000535732_length(amino acids)=595AA_BP=362
MDVMSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYATIIPRSDLNGLPSPVEERCGDSPNSEGE
TVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPE
KGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGS
QMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPN
AEMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMT
NPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSE

--------------------------------------------------------------
>80910_80910_5_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000402466_LMCD1_chr3_8574423_ENST00000157600_length(transcript)=3128nt_BP=1551nt
GCTCAGAGACTCACGCAGCCCCAGTCCCGCCAGTCCGCCAACACAGTAGTGCCGGCCCCCCTCTTTCCCTGGCCCTGCCCCCCCTCCCCG
CCTTTGGCTCGCTCCGCCTTTCTGCCCCCCACCCCCACCTCACGGGTACGGGCCATTCCCGGCCAGGAAACGCCGTGGCGCCGCGTTGGG
CCTAACTCGAGTCCTGCCGCCTCCCGGGAGTGCCGTGCGCCGCAGCCCGGGCCCAGGCCCCGGCAGCGCCTGGGACAAGGTCTTCAGAAC
TACTAGCAGATAATTTGGGGGGACTTCATATTCAGAAGTCTATATAAAGGATTCCTCATGTCCATAACATGTTGGATGAGGCTCTGCAGC
TCACCCCCACTCTCAGAGTGGTCAGTCTCCATTAATTGGACCCCGTGATTTCCAATCTCTGCTGTGTTGGACGTCATGAGCATTGCAATC
CCTCTGGGAGTCACCACATCAGATACATCCTACTCAGATATGGCTGCTGGATCAGACCCTGAATCTGTGGAGGCTAGTCCAGCAGTTAAT
GAGAAGAGCGTGTATTCCACTCATAATTATGGGACCACTCAGAGGCATGGGTGTCGAGGACTGCCTTATGCTACGATCATCCCTCGTTCT
GACCTGAATGGCCTGCCGTCGCCTGTAGAGGAACGCTGTGGAGACAGCCCGAACTCTGAAGGAGAAACTGTACCTACCTGGTGTCCTTGT
GGTCTTTCTCAGGATGGCTTCCTTCTCAACTGTGACAAGTGCAGGGGAATGAGCAGGGGGAAGGTTATTAGACTTCATCGGCGGAAGCAG
GACAACATATCAGGTGGGGATAGCAGTGCAACAGAAAGCTGGGATGAGGAGCTTTCTCCTTCCACTGTGTTGTATACAGCAACACAGCAC
ACACCTACAAGCATCACCTTAACTGTTAGAAGAACCAAACCCAAGAAGCGGAAAAAGAGTCCAGAAAAGGGTCGTGCAGCACCAAAGACG
AAGAAAATCAAGGCATTTCGAGAGGGATCCCGGAAGTCCTTGCGGATGAAGAATTCTCCCTCTGAAGCACAGAATTTAGATGAGAATACA
ACTGAGGGCTGGGAAAATCGGATAAGACTATGGACTGACCAGTATGAAGAAGCTTTCACTAATCAGTACAGTGCAGATGTACAGAACGCG
CTTGAACAACACCTACATTCTAGCAAGGAATTTGTGGGCAAACCTACTATTTTAGACACTATTAATAAGACTGAATTGGCCTGTAATAAC
ACAGTTATTGGTTCCCAAATGCAGTTACAGCTGGGAAGAGTCACTCGTGTTCAAAAGCACCGGAAGATCCTGAGGGCTGCAAGAGATTTG
GCTTTGGACACTCTTATAATAGAGTATCGTGGGAAAGTCATGTTACGACAGCAATTTGAGGTCAATGGGCATTTCTTCAAAAAACCATAC
CCCTTTGTGCTCTTCTACTCAAAATTCAATGGTGTAGAGATGTGTGTGGATGCCCGTACTTTCGGTAATGATGCTCGGTTCATCAGAAGA
TCATGTACACCAAATGCAGAGATGTCCCTGGGCCAGCTGCAGTCAGCAAGAGGTGTGGCATGTTTGGGATGCAAGGGGACGTGTTCGGGC
TTCGAGCCACATTCATGGAGGAAAATATGCAAGTCTTGCAAATGCAGCCAAGAGGACCACTGCCTAACATCTGACCTAGAAGACGATCGG
AAAATTGGCCGCTTGCTGATGGACTCCAAGTATTCCACCCTCACTGCTCGGGTGAAAGGCGGGGACGGCATCCGGATTTACAAGAGGAAC
CGGATGATCATGACCAACCCTATTGCTACTGGGAAAGATCCCACTTTTGACACCATCACCTACGAGTGGGCTCCCCCTGGAGTCACCCAG
AAACTGGGACTGCAGTACATGGAGCTCATCCCCAAGGAGAAGCAGCCAGTGACAGGCACAGAGGGTGCCTTTTACCGCCGCCGCCAGCTC
ATGCACCAGCTCCCCATCTATGACCAGGATCCCTCGCGCTGCCGTGGACTTTTGGAGAATGAGTTGAAACTGATGGAAGAATTTGTCAAG
CAATATAAGAGCGAGGCCCTCGGCGTGGGAGAAGTGGCCCTCCCGGGGCAGGGTGGCTTGCCCAAGGAGGAGGGGAAGCAGCAGGAAAAG
CCAGAGGGGGCAGAGACCACTGCTGCTACCACCAACGGCAGTCTCAGTGACCCGTCCAAAGAAGTGGAATACGTCTGCGAGCTCTGCAAG
GGAGCGGCCCCTCCTGACAGCCCCGTGGTCTACTCGGACAGGGCAGGCTACAACAAGCAGTGGCACCCCACCTGCTTTGTGTGTGCCAAG
TGCTCCGAGCCGCTGGTGGACCTCATCTACTTCTGGAAGGATGGTGCACCCTGGTGCGGCCGCCATTACTGCGAGAGTCTGCGGCCCCGG
TGCTCCGGCTGCGATGAGATAATATTCGCTGAGGACTACCAGCGTGTGGAAGATCTGGCCTGGCACCGAAAGCACTTTGTCTGTGAGGGT
TGTGAGCAGCTGCTGAGCGGCCGGGCGTACATCGTCACCAAGGGTCAGCTTCTGTGCCCAACTTGCAGCAAGTCCAAACGCTCCTGAAGG
GCTGCCCACCCACAGCCAGAATCCACAGGATCCCACCGAGAAGGAGAGCCAGGTGTGCCGAGACCATCCTAAGGGTCCGATGTGACAGCA
AGCAAGTGAAATAAACAATGATTTGCTTTTCAGTGAGAATATATATATGAGATATATATAGATATATATTCTAGGTTGGGTGGTGGTAGA
TCCTTGAGGGTCAGTAGTTTCAAAACCAAAAATATTCTAAGAAGTCTTAGGATGGAGTTCCTTTTCTTTCTGTTGTTGTTTCCCAGCTAC
AACCAACTAAAGACACAAATGGCGTTCTGCAAGGGGACTCTGGGAGGAGTTTTCCAGAATGCAATTCCGAGTGAGCAAATCGCATAGCTG
TAGAATGTGCGTGCTTTTTTGTGGACACAGGAGCTCCTCCAGGAGCAGGCTGGGATCCCAACTATCGCTTGTTGCCTCTTTTTCAAGTGG

>80910_80910_5_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000402466_LMCD1_chr3_8574423_ENST00000157600_length(amino acids)=726AA_BP=375
MDVMSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYATIIPRSDLNGLPSPVEERCGDSPNSEGE
TVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPE
KGRAAPKTKKIKAFREGSRKSLRMKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTIN
KTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFG
NDARFIRRSCTPNAEMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDDRKIGRLLMDSKYSTLTARVKGGD
GIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENEL
KLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWH
PTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTC

--------------------------------------------------------------
>80910_80910_6_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000402466_LMCD1_chr3_8574423_ENST00000535732_length(transcript)=2253nt_BP=1551nt
GCTCAGAGACTCACGCAGCCCCAGTCCCGCCAGTCCGCCAACACAGTAGTGCCGGCCCCCCTCTTTCCCTGGCCCTGCCCCCCCTCCCCG
CCTTTGGCTCGCTCCGCCTTTCTGCCCCCCACCCCCACCTCACGGGTACGGGCCATTCCCGGCCAGGAAACGCCGTGGCGCCGCGTTGGG
CCTAACTCGAGTCCTGCCGCCTCCCGGGAGTGCCGTGCGCCGCAGCCCGGGCCCAGGCCCCGGCAGCGCCTGGGACAAGGTCTTCAGAAC
TACTAGCAGATAATTTGGGGGGACTTCATATTCAGAAGTCTATATAAAGGATTCCTCATGTCCATAACATGTTGGATGAGGCTCTGCAGC
TCACCCCCACTCTCAGAGTGGTCAGTCTCCATTAATTGGACCCCGTGATTTCCAATCTCTGCTGTGTTGGACGTCATGAGCATTGCAATC
CCTCTGGGAGTCACCACATCAGATACATCCTACTCAGATATGGCTGCTGGATCAGACCCTGAATCTGTGGAGGCTAGTCCAGCAGTTAAT
GAGAAGAGCGTGTATTCCACTCATAATTATGGGACCACTCAGAGGCATGGGTGTCGAGGACTGCCTTATGCTACGATCATCCCTCGTTCT
GACCTGAATGGCCTGCCGTCGCCTGTAGAGGAACGCTGTGGAGACAGCCCGAACTCTGAAGGAGAAACTGTACCTACCTGGTGTCCTTGT
GGTCTTTCTCAGGATGGCTTCCTTCTCAACTGTGACAAGTGCAGGGGAATGAGCAGGGGGAAGGTTATTAGACTTCATCGGCGGAAGCAG
GACAACATATCAGGTGGGGATAGCAGTGCAACAGAAAGCTGGGATGAGGAGCTTTCTCCTTCCACTGTGTTGTATACAGCAACACAGCAC
ACACCTACAAGCATCACCTTAACTGTTAGAAGAACCAAACCCAAGAAGCGGAAAAAGAGTCCAGAAAAGGGTCGTGCAGCACCAAAGACG
AAGAAAATCAAGGCATTTCGAGAGGGATCCCGGAAGTCCTTGCGGATGAAGAATTCTCCCTCTGAAGCACAGAATTTAGATGAGAATACA
ACTGAGGGCTGGGAAAATCGGATAAGACTATGGACTGACCAGTATGAAGAAGCTTTCACTAATCAGTACAGTGCAGATGTACAGAACGCG
CTTGAACAACACCTACATTCTAGCAAGGAATTTGTGGGCAAACCTACTATTTTAGACACTATTAATAAGACTGAATTGGCCTGTAATAAC
ACAGTTATTGGTTCCCAAATGCAGTTACAGCTGGGAAGAGTCACTCGTGTTCAAAAGCACCGGAAGATCCTGAGGGCTGCAAGAGATTTG
GCTTTGGACACTCTTATAATAGAGTATCGTGGGAAAGTCATGTTACGACAGCAATTTGAGGTCAATGGGCATTTCTTCAAAAAACCATAC
CCCTTTGTGCTCTTCTACTCAAAATTCAATGGTGTAGAGATGTGTGTGGATGCCCGTACTTTCGGTAATGATGCTCGGTTCATCAGAAGA
TCATGTACACCAAATGCAGAGATGTCCCTGGGCCAGCTGCAGTCAGCAAGAGGTGTGGCATGTTTGGGATGCAAGGGGACGTGTTCGGGC
TTCGAGCCACATTCATGGAGGAAAATATGCAAGTCTTGCAAATGCAGCCAAGAGGACCACTGCCTAACATCTGACCTAGAAGACGATCGG
AAAATTGGCCGCTTGCTGATGGACTCCAAGTATTCCACCCTCACTGCTCGGGTGAAAGGCGGGGACGGCATCCGGATTTACAAGAGGAAC
CGGATGATCATGACCAACCCTATTGCTACTGGGAAAGATCCCACTTTTGACACCATCACCTACGAGTGGGCTCCCCCTGGAGTCACCCAG
AAACTGGGACTGCAGTACATGGAGCTCATCCCCAAGGAGAAGCAGCCAGTGACAGGCACAGAGGGTGCCTTTTACCGCCGCCGCCAGCTC
ATGCACCAGCTCCCCATCTATGACCAGGATCCCTCGCGCTGCCGTGGACTTTTGGAGAATGAGTTGAAACTGATGGAAGAATTTGTCAAG
CAATATAAGAGCGAGGCCCTCGGCGTGGGAGAAGTGGCCCTCCCGGGGCAGGGTGGCTTGCCCAAGGAGGAGGGGAAGCAGCAGGAAAAG
CCAGAGGGGGCAGAGACCACTGCTGCTACCACCAACGGCAGTCTCAGTGACCCGTCCAAAGAAGTGGAATACAAGCCAGTCCCACTCGTG

>80910_80910_6_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000402466_LMCD1_chr3_8574423_ENST00000535732_length(amino acids)=608AA_BP=375
MDVMSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYATIIPRSDLNGLPSPVEERCGDSPNSEGE
TVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPE
KGRAAPKTKKIKAFREGSRKSLRMKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTIN
KTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFG
NDARFIRRSCTPNAEMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDDRKIGRLLMDSKYSTLTARVKGGD
GIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENEL

--------------------------------------------------------------
>80910_80910_7_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000406341_LMCD1_chr3_8574423_ENST00000157600_length(transcript)=2844nt_BP=1267nt
CTCGAGTCCTGCCGCCTCCCGGGAGTGCCGTGCGCCGCAGCCCGGGCCCAGGCCCCGGCAGCGCCTGGGACAAGGATTCCTCATGTCCAT
AACATGTTGGATGAGGCTCTGCAGCTCACCCCCACTCTCAGAGTGGTCAGTCTCCATTAATTGGACCCCGTGATTTCCAATCTCTGCTGT
GTTGGACGTCATGAGCATTGCAATCCCTCTGGGAGTCACCACATCAGATACATCCTACTCAGATATGGCTGCTGGATCAGACCCTGAATC
TGTGGAGGCTAGTCCAGCAGTTAATGAGAAGAGCGTGTATTCCACTCATAATTATGGGACCACTCAGAGGCATGGGTGTCGAGGACTGCC
TTATGCTACGATCATCCCTCGTTCTGACCTGAATGGCCTGCCGTCGCCTGTAGAGGAACGCTGTGGAGACAGCCCGAACTCTGAAGGAGA
AACTGTACCTACCTGGTGTCCTTGTGGTCTTTCTCAGGATGGCTTCCTTCTCAACTGTGACAAGTGCAGGGGAATGAGCAGGGGGAAGGT
TATTAGACTTCATCGGCGGAAGCAGGACAACATATCAGGTGGGGATAGCAGTGCAACAGAAAGCTGGGATGAGGAGCTTTCTCCTTCCAC
TGTGTTGTATACAGCAACACAGCACACACCTACAAGCATCACCTTAACTGTTAGAAGAACCAAACCCAAGAAGCGGAAAAAGAGTCCAGA
AAAGGGTCGTGCAGCACCAAAGACGAAGAAAATCAAGAATTCTCCCTCTGAAGCACAGAATTTAGATGAGAATACAACTGAGGGCTGGGA
AAATCGGATAAGACTATGGACTGACCAGTATGAAGAAGCTTTCACTAATCAGTACAGTGCAGATGTACAGAACGCGCTTGAACAACACCT
ACATTCTAGCAAGGAATTTGTGGGCAAACCTACTATTTTAGACACTATTAATAAGACTGAATTGGCCTGTAATAACACAGTTATTGGTTC
CCAAATGCAGTTACAGCTGGGAAGAGTCACTCGTGTTCAAAAGCACCGGAAGATCCTGAGGGCTGCAAGAGATTTGGCTTTGGACACTCT
TATAATAGAGTATCGTGGGAAAGTCATGTTACGACAGCAATTTGAGGTCAATGGGCATTTCTTCAAAAAACCATACCCCTTTGTGCTCTT
CTACTCAAAATTCAATGGTGTAGAGATGTGTGTGGATGCCCGTACTTTCGGTAATGATGCTCGGTTCATCAGAAGATCATGTACACCAAA
TGCAGAGATGTCCCTGGGCCAGCTGCAGTCAGCAAGAGGTGTGGCATGTTTGGGATGCAAGGGGACGTGTTCGGGCTTCGAGCCACATTC
ATGGAGGAAAATATGCAAGTCTTGCAAATGCAGCCAAGAGGACCACTGCCTAACATCTGACCTAGAAGACGATCGGAAAATTGGCCGCTT
GCTGATGGACTCCAAGTATTCCACCCTCACTGCTCGGGTGAAAGGCGGGGACGGCATCCGGATTTACAAGAGGAACCGGATGATCATGAC
CAACCCTATTGCTACTGGGAAAGATCCCACTTTTGACACCATCACCTACGAGTGGGCTCCCCCTGGAGTCACCCAGAAACTGGGACTGCA
GTACATGGAGCTCATCCCCAAGGAGAAGCAGCCAGTGACAGGCACAGAGGGTGCCTTTTACCGCCGCCGCCAGCTCATGCACCAGCTCCC
CATCTATGACCAGGATCCCTCGCGCTGCCGTGGACTTTTGGAGAATGAGTTGAAACTGATGGAAGAATTTGTCAAGCAATATAAGAGCGA
GGCCCTCGGCGTGGGAGAAGTGGCCCTCCCGGGGCAGGGTGGCTTGCCCAAGGAGGAGGGGAAGCAGCAGGAAAAGCCAGAGGGGGCAGA
GACCACTGCTGCTACCACCAACGGCAGTCTCAGTGACCCGTCCAAAGAAGTGGAATACGTCTGCGAGCTCTGCAAGGGAGCGGCCCCTCC
TGACAGCCCCGTGGTCTACTCGGACAGGGCAGGCTACAACAAGCAGTGGCACCCCACCTGCTTTGTGTGTGCCAAGTGCTCCGAGCCGCT
GGTGGACCTCATCTACTTCTGGAAGGATGGTGCACCCTGGTGCGGCCGCCATTACTGCGAGAGTCTGCGGCCCCGGTGCTCCGGCTGCGA
TGAGATAATATTCGCTGAGGACTACCAGCGTGTGGAAGATCTGGCCTGGCACCGAAAGCACTTTGTCTGTGAGGGTTGTGAGCAGCTGCT
GAGCGGCCGGGCGTACATCGTCACCAAGGGTCAGCTTCTGTGCCCAACTTGCAGCAAGTCCAAACGCTCCTGAAGGGCTGCCCACCCACA
GCCAGAATCCACAGGATCCCACCGAGAAGGAGAGCCAGGTGTGCCGAGACCATCCTAAGGGTCCGATGTGACAGCAAGCAAGTGAAATAA
ACAATGATTTGCTTTTCAGTGAGAATATATATATGAGATATATATAGATATATATTCTAGGTTGGGTGGTGGTAGATCCTTGAGGGTCAG
TAGTTTCAAAACCAAAAATATTCTAAGAAGTCTTAGGATGGAGTTCCTTTTCTTTCTGTTGTTGTTTCCCAGCTACAACCAACTAAAGAC
ACAAATGGCGTTCTGCAAGGGGACTCTGGGAGGAGTTTTCCAGAATGCAATTCCGAGTGAGCAAATCGCATAGCTGTAGAATGTGCGTGC
TTTTTTGTGGACACAGGAGCTCCTCCAGGAGCAGGCTGGGATCCCAACTATCGCTTGTTGCCTCTTTTTCAAGTGGAATTTGAATTTTAA

>80910_80910_7_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000406341_LMCD1_chr3_8574423_ENST00000157600_length(amino acids)=713AA_BP=362
MDVMSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYATIIPRSDLNGLPSPVEERCGDSPNSEGE
TVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPE
KGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGS
QMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPN
AEMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMT
NPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSE
ALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPL

--------------------------------------------------------------
>80910_80910_8_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000406341_LMCD1_chr3_8574423_ENST00000535732_length(transcript)=1969nt_BP=1267nt
CTCGAGTCCTGCCGCCTCCCGGGAGTGCCGTGCGCCGCAGCCCGGGCCCAGGCCCCGGCAGCGCCTGGGACAAGGATTCCTCATGTCCAT
AACATGTTGGATGAGGCTCTGCAGCTCACCCCCACTCTCAGAGTGGTCAGTCTCCATTAATTGGACCCCGTGATTTCCAATCTCTGCTGT
GTTGGACGTCATGAGCATTGCAATCCCTCTGGGAGTCACCACATCAGATACATCCTACTCAGATATGGCTGCTGGATCAGACCCTGAATC
TGTGGAGGCTAGTCCAGCAGTTAATGAGAAGAGCGTGTATTCCACTCATAATTATGGGACCACTCAGAGGCATGGGTGTCGAGGACTGCC
TTATGCTACGATCATCCCTCGTTCTGACCTGAATGGCCTGCCGTCGCCTGTAGAGGAACGCTGTGGAGACAGCCCGAACTCTGAAGGAGA
AACTGTACCTACCTGGTGTCCTTGTGGTCTTTCTCAGGATGGCTTCCTTCTCAACTGTGACAAGTGCAGGGGAATGAGCAGGGGGAAGGT
TATTAGACTTCATCGGCGGAAGCAGGACAACATATCAGGTGGGGATAGCAGTGCAACAGAAAGCTGGGATGAGGAGCTTTCTCCTTCCAC
TGTGTTGTATACAGCAACACAGCACACACCTACAAGCATCACCTTAACTGTTAGAAGAACCAAACCCAAGAAGCGGAAAAAGAGTCCAGA
AAAGGGTCGTGCAGCACCAAAGACGAAGAAAATCAAGAATTCTCCCTCTGAAGCACAGAATTTAGATGAGAATACAACTGAGGGCTGGGA
AAATCGGATAAGACTATGGACTGACCAGTATGAAGAAGCTTTCACTAATCAGTACAGTGCAGATGTACAGAACGCGCTTGAACAACACCT
ACATTCTAGCAAGGAATTTGTGGGCAAACCTACTATTTTAGACACTATTAATAAGACTGAATTGGCCTGTAATAACACAGTTATTGGTTC
CCAAATGCAGTTACAGCTGGGAAGAGTCACTCGTGTTCAAAAGCACCGGAAGATCCTGAGGGCTGCAAGAGATTTGGCTTTGGACACTCT
TATAATAGAGTATCGTGGGAAAGTCATGTTACGACAGCAATTTGAGGTCAATGGGCATTTCTTCAAAAAACCATACCCCTTTGTGCTCTT
CTACTCAAAATTCAATGGTGTAGAGATGTGTGTGGATGCCCGTACTTTCGGTAATGATGCTCGGTTCATCAGAAGATCATGTACACCAAA
TGCAGAGATGTCCCTGGGCCAGCTGCAGTCAGCAAGAGGTGTGGCATGTTTGGGATGCAAGGGGACGTGTTCGGGCTTCGAGCCACATTC
ATGGAGGAAAATATGCAAGTCTTGCAAATGCAGCCAAGAGGACCACTGCCTAACATCTGACCTAGAAGACGATCGGAAAATTGGCCGCTT
GCTGATGGACTCCAAGTATTCCACCCTCACTGCTCGGGTGAAAGGCGGGGACGGCATCCGGATTTACAAGAGGAACCGGATGATCATGAC
CAACCCTATTGCTACTGGGAAAGATCCCACTTTTGACACCATCACCTACGAGTGGGCTCCCCCTGGAGTCACCCAGAAACTGGGACTGCA
GTACATGGAGCTCATCCCCAAGGAGAAGCAGCCAGTGACAGGCACAGAGGGTGCCTTTTACCGCCGCCGCCAGCTCATGCACCAGCTCCC
CATCTATGACCAGGATCCCTCGCGCTGCCGTGGACTTTTGGAGAATGAGTTGAAACTGATGGAAGAATTTGTCAAGCAATATAAGAGCGA
GGCCCTCGGCGTGGGAGAAGTGGCCCTCCCGGGGCAGGGTGGCTTGCCCAAGGAGGAGGGGAAGCAGCAGGAAAAGCCAGAGGGGGCAGA

>80910_80910_8_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000406341_LMCD1_chr3_8574423_ENST00000535732_length(amino acids)=596AA_BP=362
MDVMSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYATIIPRSDLNGLPSPVEERCGDSPNSEGE
TVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPE
KGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGS
QMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPN
AEMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMT
NPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSE

--------------------------------------------------------------
>80910_80910_9_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000407969_LMCD1_chr3_8574423_ENST00000157600_length(transcript)=2725nt_BP=1148nt
CTGTGTTGGACGTCATGAGCATTGCAATCCCTCTGGGAGTCACCACATCAGATACATCCTACTCAGATATGGCTGCTGGATCAGACCCTG
AATCTGTGGAGGCTAGTCCAGCAGTTAATGAGAAGAGCGTGTATTCCACTCATAATTATGGGACCACTCAGAGGCATGGGTGTCGAGGAC
TGCCTTATGCTGATCATAATTACGGAGCCCCTCCTCCTCCGACACCTCCTGCTTCTCCCCCTGTCCAGACGATCATCCCTCGTTCTGACC
TGAATGGCCTGCCGTCGCCTGTAGAGGAACGCTGTGGAGACAGCCCGAACTCTGAAGGAGAAACTGTACCTACCTGGTGTCCTTGTGGTC
TTTCTCAGGATGGCTTCCTTCTCAACTGTGACAAGTGCAGGGGAATGAGCAGGGGGAAGGTTATTAGACTTCATCGGCGGAAGCAGGACA
ACATATCAGGTGGGGATAGCAGTGCAACAGAAAGCTGGGATGAGGAGCTTTCTCCTTCCACTGTGTTGTATACAGCAACACAGCACACAC
CTACAAGCATCACCTTAACTGTTAGAAGAACCAAACCCAAGAAGCGGAAAAAGAGTCCAGAAAAGGGTCGTGCAGCACCAAAGACGAAGA
AAATCAAGAATTCTCCCTCTGAAGCACAGAATTTAGATGAGAATACAACTGAGGGCTGGGAAAATCGGATAAGACTATGGACTGACCAGT
ATGAAGAAGCTTTCACTAATCAGTACAGTGCAGATGTACAGAACGCGCTTGAACAACACCTACATTCTAGCAAGGAATTTGTGGGCAAAC
CTACTATTTTAGACACTATTAATAAGACTGAATTGGCCTGTAATAACACAGTTATTGGTTCCCAAATGCAGTTACAGCTGGGAAGAGTCA
CTCGTGTTCAAAAGCACCGGAAGATCCTGAGGGCTGCAAGAGATTTGGCTTTGGACACTCTTATAATAGAGTATCGTGGGAAAGTCATGT
TACGACAGCAATTTGAGGTCAATGGGCATTTCTTCAAAAAACCATACCCCTTTGTGCTCTTCTACTCAAAATTCAATGGTGTAGAGATGT
GTGTGGATGCCCGTACTTTCGGTAATGATGCTCGGTTCATCAGAAGATCATGTACACCAAATGCAGAGATGTCCCTGGGCCAGCTGCAGT
CAGCAAGAGGTGTGGCATGTTTGGGATGCAAGGGGACGTGTTCGGGCTTCGAGCCACATTCATGGAGGAAAATATGCAAGTCTTGCAAAT
GCAGCCAAGAGGACCACTGCCTAACATCTGACCTAGAAGACGATCGGAAAATTGGCCGCTTGCTGATGGACTCCAAGTATTCCACCCTCA
CTGCTCGGGTGAAAGGCGGGGACGGCATCCGGATTTACAAGAGGAACCGGATGATCATGACCAACCCTATTGCTACTGGGAAAGATCCCA
CTTTTGACACCATCACCTACGAGTGGGCTCCCCCTGGAGTCACCCAGAAACTGGGACTGCAGTACATGGAGCTCATCCCCAAGGAGAAGC
AGCCAGTGACAGGCACAGAGGGTGCCTTTTACCGCCGCCGCCAGCTCATGCACCAGCTCCCCATCTATGACCAGGATCCCTCGCGCTGCC
GTGGACTTTTGGAGAATGAGTTGAAACTGATGGAAGAATTTGTCAAGCAATATAAGAGCGAGGCCCTCGGCGTGGGAGAAGTGGCCCTCC
CGGGGCAGGGTGGCTTGCCCAAGGAGGAGGGGAAGCAGCAGGAAAAGCCAGAGGGGGCAGAGACCACTGCTGCTACCACCAACGGCAGTC
TCAGTGACCCGTCCAAAGAAGTGGAATACGTCTGCGAGCTCTGCAAGGGAGCGGCCCCTCCTGACAGCCCCGTGGTCTACTCGGACAGGG
CAGGCTACAACAAGCAGTGGCACCCCACCTGCTTTGTGTGTGCCAAGTGCTCCGAGCCGCTGGTGGACCTCATCTACTTCTGGAAGGATG
GTGCACCCTGGTGCGGCCGCCATTACTGCGAGAGTCTGCGGCCCCGGTGCTCCGGCTGCGATGAGATAATATTCGCTGAGGACTACCAGC
GTGTGGAAGATCTGGCCTGGCACCGAAAGCACTTTGTCTGTGAGGGTTGTGAGCAGCTGCTGAGCGGCCGGGCGTACATCGTCACCAAGG
GTCAGCTTCTGTGCCCAACTTGCAGCAAGTCCAAACGCTCCTGAAGGGCTGCCCACCCACAGCCAGAATCCACAGGATCCCACCGAGAAG
GAGAGCCAGGTGTGCCGAGACCATCCTAAGGGTCCGATGTGACAGCAAGCAAGTGAAATAAACAATGATTTGCTTTTCAGTGAGAATATA
TATATGAGATATATATAGATATATATTCTAGGTTGGGTGGTGGTAGATCCTTGAGGGTCAGTAGTTTCAAAACCAAAAATATTCTAAGAA
GTCTTAGGATGGAGTTCCTTTTCTTTCTGTTGTTGTTTCCCAGCTACAACCAACTAAAGACACAAATGGCGTTCTGCAAGGGGACTCTGG
GAGGAGTTTTCCAGAATGCAATTCCGAGTGAGCAAATCGCATAGCTGTAGAATGTGCGTGCTTTTTTGTGGACACAGGAGCTCCTCCAGG
AGCAGGCTGGGATCCCAACTATCGCTTGTTGCCTCTTTTTCAAGTGGAATTTGAATTTTAAATAAACAACTTTTTTTGGCATGATAAACA

>80910_80910_9_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000407969_LMCD1_chr3_8574423_ENST00000157600_length(amino acids)=732AA_BP=381
MDVMSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYADHNYGAPPPPTPPASPPVQTIIPRSDLN
GLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPT
SITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPT
ILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCV
DARTFGNDARFIRRSCTPNAEMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDDRKIGRLLMDSKYSTLTA
RVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRG
LLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVEYVCELCKGAAPPDSPVVYSDRAG
YNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQ

--------------------------------------------------------------
>80910_80910_10_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000407969_LMCD1_chr3_8574423_ENST00000535732_length(transcript)=1850nt_BP=1148nt
CTGTGTTGGACGTCATGAGCATTGCAATCCCTCTGGGAGTCACCACATCAGATACATCCTACTCAGATATGGCTGCTGGATCAGACCCTG
AATCTGTGGAGGCTAGTCCAGCAGTTAATGAGAAGAGCGTGTATTCCACTCATAATTATGGGACCACTCAGAGGCATGGGTGTCGAGGAC
TGCCTTATGCTGATCATAATTACGGAGCCCCTCCTCCTCCGACACCTCCTGCTTCTCCCCCTGTCCAGACGATCATCCCTCGTTCTGACC
TGAATGGCCTGCCGTCGCCTGTAGAGGAACGCTGTGGAGACAGCCCGAACTCTGAAGGAGAAACTGTACCTACCTGGTGTCCTTGTGGTC
TTTCTCAGGATGGCTTCCTTCTCAACTGTGACAAGTGCAGGGGAATGAGCAGGGGGAAGGTTATTAGACTTCATCGGCGGAAGCAGGACA
ACATATCAGGTGGGGATAGCAGTGCAACAGAAAGCTGGGATGAGGAGCTTTCTCCTTCCACTGTGTTGTATACAGCAACACAGCACACAC
CTACAAGCATCACCTTAACTGTTAGAAGAACCAAACCCAAGAAGCGGAAAAAGAGTCCAGAAAAGGGTCGTGCAGCACCAAAGACGAAGA
AAATCAAGAATTCTCCCTCTGAAGCACAGAATTTAGATGAGAATACAACTGAGGGCTGGGAAAATCGGATAAGACTATGGACTGACCAGT
ATGAAGAAGCTTTCACTAATCAGTACAGTGCAGATGTACAGAACGCGCTTGAACAACACCTACATTCTAGCAAGGAATTTGTGGGCAAAC
CTACTATTTTAGACACTATTAATAAGACTGAATTGGCCTGTAATAACACAGTTATTGGTTCCCAAATGCAGTTACAGCTGGGAAGAGTCA
CTCGTGTTCAAAAGCACCGGAAGATCCTGAGGGCTGCAAGAGATTTGGCTTTGGACACTCTTATAATAGAGTATCGTGGGAAAGTCATGT
TACGACAGCAATTTGAGGTCAATGGGCATTTCTTCAAAAAACCATACCCCTTTGTGCTCTTCTACTCAAAATTCAATGGTGTAGAGATGT
GTGTGGATGCCCGTACTTTCGGTAATGATGCTCGGTTCATCAGAAGATCATGTACACCAAATGCAGAGATGTCCCTGGGCCAGCTGCAGT
CAGCAAGAGGTGTGGCATGTTTGGGATGCAAGGGGACGTGTTCGGGCTTCGAGCCACATTCATGGAGGAAAATATGCAAGTCTTGCAAAT
GCAGCCAAGAGGACCACTGCCTAACATCTGACCTAGAAGACGATCGGAAAATTGGCCGCTTGCTGATGGACTCCAAGTATTCCACCCTCA
CTGCTCGGGTGAAAGGCGGGGACGGCATCCGGATTTACAAGAGGAACCGGATGATCATGACCAACCCTATTGCTACTGGGAAAGATCCCA
CTTTTGACACCATCACCTACGAGTGGGCTCCCCCTGGAGTCACCCAGAAACTGGGACTGCAGTACATGGAGCTCATCCCCAAGGAGAAGC
AGCCAGTGACAGGCACAGAGGGTGCCTTTTACCGCCGCCGCCAGCTCATGCACCAGCTCCCCATCTATGACCAGGATCCCTCGCGCTGCC
GTGGACTTTTGGAGAATGAGTTGAAACTGATGGAAGAATTTGTCAAGCAATATAAGAGCGAGGCCCTCGGCGTGGGAGAAGTGGCCCTCC
CGGGGCAGGGTGGCTTGCCCAAGGAGGAGGGGAAGCAGCAGGAAAAGCCAGAGGGGGCAGAGACCACTGCTGCTACCACCAACGGCAGTC

>80910_80910_10_SETD5-LMCD1_SETD5_chr3_9483929_ENST00000407969_LMCD1_chr3_8574423_ENST00000535732_length(amino acids)=615AA_BP=381
MDVMSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYADHNYGAPPPPTPPASPPVQTIIPRSDLN
GLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPT
SITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPT
ILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCV
DARTFGNDARFIRRSCTPNAEMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDDRKIGRLLMDSKYSTLTA
RVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SETD5-LMCD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SETD5-LMCD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SETD5-LMCD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource