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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SFI1-EFCAB4B (FusionGDB2 ID:81084)

Fusion Gene Summary for SFI1-EFCAB4B

Fusion gene summary

Fusion gene information	Fusion gene name: SFI1-EFCAB4B
	Fusion gene ID: 81084
		Hgene	Tgene
	Gene symbol	SFI1	EFCAB4B
	Gene ID	9814	84766
	Gene name	SFI1 centrin binding protein	calcium release activated channel regulator 2A
	Synonyms	PISD\|PPP1R139\|hSfi1p	EFCAB4B
	Cytomap	22q12.2	12p13.32
	Type of gene	protein-coding	protein-coding
	Description	protein SFI1 homologSfi1 homolog, spindle assembly associatedhomolog of yeast Sfi1protein phosphatase 1, regulatory subunit 139	EF-hand calcium-binding domain-containing protein 4BCRAC channel regulator 2ACRAC regulator 2ACa2+ release-activated Ca2+ (CRAC) channel regulator 2AEF-hand calcium binding domain 4Bcalcium release-activated calcium channel regulator 2A
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000400288, ENST00000400289, ENST00000414585, ENST00000432498, ENST00000443011, ENST00000443326, ENST00000540643, ENST00000474741,	ENST00000252322, ENST00000514026, ENST00000440314, ENST00000444507,
Fusion gene scores	* DoF score	7 X 6 X 5=210	2 X 2 X 2=8
	# samples	7	2
	** MAII score	log2(7/210*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(2/8*10)=1.32192809488736
Context	PubMed: SFI1 [Title/Abstract] AND EFCAB4B [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SFI1(31985563)-EFCAB4B(3753806), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	SFI1	GO:0010923	negative regulation of phosphatase activity	19389623

Fusion gene breakpoints across SFI1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across EFCAB4B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	TGCT	TCGA-VF-A8AD-01A	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-

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Fusion Gene ORF analysis for SFI1-EFCAB4B

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000400288	ENST00000252322	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000400288	ENST00000514026	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000400289	ENST00000252322	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000400289	ENST00000514026	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000414585	ENST00000252322	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000414585	ENST00000514026	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000432498	ENST00000252322	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000432498	ENST00000514026	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000443011	ENST00000252322	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000443011	ENST00000514026	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000443326	ENST00000252322	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000443326	ENST00000514026	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000540643	ENST00000252322	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
5CDS-intron	ENST00000540643	ENST00000514026	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000400288	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000400288	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000400289	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000400289	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000414585	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000414585	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000432498	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000432498	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000443011	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000443011	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000443326	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000443326	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000540643	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
In-frame	ENST00000540643	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
intron-3CDS	ENST00000474741	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
intron-3CDS	ENST00000474741	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
intron-intron	ENST00000474741	ENST00000252322	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-
intron-intron	ENST00000474741	ENST00000514026	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000443326	SFI1	chr22	31985563	-	ENST00000440314	EFCAB4B	chr12	3753806	-	2796	1691	393	2768	791
ENST00000443326	SFI1	chr22	31985563	-	ENST00000444507	EFCAB4B	chr12	3753806	-	2229	1691	393	1961	522
ENST00000414585	SFI1	chr22	31985563	-	ENST00000440314	EFCAB4B	chr12	3753806	-	2583	1478	393	2555	720
ENST00000414585	SFI1	chr22	31985563	-	ENST00000444507	EFCAB4B	chr12	3753806	-	2016	1478	393	1748	451
ENST00000540643	SFI1	chr22	31985563	-	ENST00000440314	EFCAB4B	chr12	3753806	-	2877	1772	393	2849	818
ENST00000540643	SFI1	chr22	31985563	-	ENST00000444507	EFCAB4B	chr12	3753806	-	2310	1772	393	2042	549
ENST00000432498	SFI1	chr22	31985563	-	ENST00000440314	EFCAB4B	chr12	3753806	-	2949	1844	393	2921	842
ENST00000432498	SFI1	chr22	31985563	-	ENST00000444507	EFCAB4B	chr12	3753806	-	2382	1844	393	2114	573
ENST00000443011	SFI1	chr22	31985563	-	ENST00000440314	EFCAB4B	chr12	3753806	-	2471	1366	281	2443	720
ENST00000443011	SFI1	chr22	31985563	-	ENST00000444507	EFCAB4B	chr12	3753806	-	1904	1366	281	1636	451
ENST00000400289	SFI1	chr22	31985563	-	ENST00000440314	EFCAB4B	chr12	3753806	-	2529	1424	126	2501	791
ENST00000400289	SFI1	chr22	31985563	-	ENST00000444507	EFCAB4B	chr12	3753806	-	1962	1424	126	1694	522
ENST00000400288	SFI1	chr22	31985563	-	ENST00000440314	EFCAB4B	chr12	3753806	-	2754	1649	105	2726	873
ENST00000400288	SFI1	chr22	31985563	-	ENST00000444507	EFCAB4B	chr12	3753806	-	2187	1649	105	1919	604

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000443326	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.005295687	0.9947043
ENST00000443326	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.018372038	0.981628
ENST00000414585	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.011163319	0.98883665
ENST00000414585	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.03803839	0.96196157
ENST00000540643	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.007578209	0.9924218
ENST00000540643	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.03408827	0.9659117
ENST00000432498	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.004714786	0.9952852
ENST00000432498	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.02015816	0.9798418
ENST00000443011	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.009353685	0.99064636
ENST00000443011	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.031342395	0.9686576
ENST00000400289	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.004875427	0.99512464
ENST00000400289	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.013950883	0.9860491
ENST00000400288	ENST00000440314	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.003664107	0.99633586
ENST00000400288	ENST00000444507	SFI1	chr22	31985563	-	EFCAB4B	chr12	3753806	-	0.015236389	0.98476356

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Fusion Genomic Features for SFI1-EFCAB4B

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SFI1-EFCAB4B

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:31985563/chr12:3753806)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400288

138_170

514

1243.0

Repeat

Note=HAT 1

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400288

172_201

514

1243.0

Repeat

Note=HAT 2

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400288

270_302

514

1243.0

Repeat

Note=HAT 3

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400288

334_368

514

1243.0

Repeat

Note=HAT 4

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400288

399_431

514

1243.0

Repeat

Note=HAT 5

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400289

138_170

432

1161.0

Repeat

Note=HAT 1

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400289

172_201

432

1161.0

Repeat

Note=HAT 2

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400289

270_302

432

1161.0

Repeat

Note=HAT 3

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400289

334_368

432

1161.0

Repeat

Note=HAT 4

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400289

399_431

432

1161.0

Repeat

Note=HAT 5

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000414585

138_170

361

989.0

Repeat

Note=HAT 1

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000414585

172_201

361

989.0

Repeat

Note=HAT 2

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000414585

270_302

361

989.0

Repeat

Note=HAT 3

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000432498

138_170

483

1212.0

Repeat

Note=HAT 1

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000432498

172_201

483

1212.0

Repeat

Note=HAT 2

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000432498

270_302

483

1212.0

Repeat

Note=HAT 3

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000432498

334_368

483

1212.0

Repeat

Note=HAT 4

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000432498

399_431

483

1212.0

Repeat

Note=HAT 5

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000443326

138_170

432

1161.0

Repeat

Note=HAT 1

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000443326

172_201

432

1161.0

Repeat

Note=HAT 2

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000443326

270_302

432

1161.0

Repeat

Note=HAT 3

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000443326

334_368

432

1161.0

Repeat

Note=HAT 4

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000443326

399_431

432

1161.0

Repeat

Note=HAT 5

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000540643

138_170

459

1188.0

Repeat

Note=HAT 1

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000540643

172_201

459

1188.0

Repeat

Note=HAT 2

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000540643

270_302

459

1188.0

Repeat

Note=HAT 3

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000540643

334_368

459

1188.0

Repeat

Note=HAT 4

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000540643

399_431

459

1188.0

Repeat

Note=HAT 5

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000252322

97_108

396.0

Calcium binding

Ontology_term=ECO:0000255

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000252322

201_382

396.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000252322

84_119

396.0

Domain

EF-hand

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000252322

552_559

396.0

Nucleotide binding

GTP

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000252322

600_604

396.0

Nucleotide binding

GTP

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000252322

659_661

396.0

Nucleotide binding

GTP

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000440314

552_559

372

732.0

Nucleotide binding

GTP

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000440314

600_604

372

732.0

Nucleotide binding

GTP

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000440314

659_661

372

732.0

Nucleotide binding

GTP

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400288

1148_1180

514

1243.0

Repeat

Note=HAT 6

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000400289

1148_1180

432

1161.0

Repeat

Note=HAT 6

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000414585

1148_1180

361

989.0

Repeat

Note=HAT 6

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000414585

334_368

361

989.0

Repeat

Note=HAT 4

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000414585

399_431

361

989.0

Repeat

Note=HAT 5

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000432498

1148_1180

483

1212.0

Repeat

Note=HAT 6

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000443326

1148_1180

432

1161.0

Repeat

Note=HAT 6

Hgene

SFI1

chr22:31985563

chr12:3753806

ENST00000540643

1148_1180

459

1188.0

Repeat

Note=HAT 6

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000440314

97_108

372

732.0

Calcium binding

Ontology_term=ECO:0000255

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000440314

201_382

372

732.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EFCAB4B

chr22:31985563

chr12:3753806

ENST00000440314

84_119

372

732.0

Domain

EF-hand

Top

Fusion Gene Sequence for SFI1-EFCAB4B

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>81084_81084_1_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000400288_EFCAB4B_chr12_3753806_ENST00000440314_length(transcript)=2754nt_BP=1649nt
AAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCCCAGTTAGAAGGGGAAGAT
AAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTGATTAAGCAGAGAATGGAG
AAGAAGGTTGATTCCAGGTATTTTAAGGATGGTGCAGTTAAGAAACCTTATTCTGCAAAGACACTGTCCAACAAGAAGTCTTCTGCATCC
TTTGGGATCCGGAGGGAGTTACCTAGTACCAGTCATCTAGTGCAGTATCGTGGCACACATACTTGTACCCGACAGGGCCGGTTAAGAGAA
CTGCGCATCAGATGCGTGGCCAGAAAGTTCTTATATTTATGGATTCGAATGACTTTTGGAAGAGTATTTCCCTCTAAAGCCAGATTTTAC
TATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAGTGGTGGGTTTTCCAGCACGAGTGGAAACTCTGTGTTCGAGCT
GACTGTCACTACAGGTATTACCTGTACAACCTGATGTTCCAGACGTGGAAGACCTATGTGCGTCAGCAGCAGGAGATGAGGAACAAGTAC
ATTAGAGCCGAGGTTCATGATGCAAAGCAAAAGATGCGACAGGCCTGGAAGTCCTGGTTGATCTACGTGGTTGTTCGTAGGACCAAACTT
CAGATGCAGACTACAGCTCTGGAGTTTAGGCAACGGATTATCTTACGGGTGTGGTGGAGCACGTGGAGGCAGCGACTAGGACAGGTCCGT
GTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGCCTCCAGGTGCAGGCTTGGTCACAGTGGCGGGAACAGCTCCTG
TATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACATCATCAGCACTGGCAAAAACGGAGATTTCTAAAGGCCTGGCTTGAA
TACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAGCGATTCCATCATGTCACTGTGCTCCAGATATACTTCTGTGAC
TGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCCCAGGTGGAGAAACTGGCCAGGAAGATGGCCCTGCGGCGCGCC
TTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCTGCCCAGTTTGAGATGGCAGAAGAGCACCACAGGCACAGCCAGCTG
TATTTTTGCTTTAGAGCCCTAAAAGACAATGTGACCCACGCTCATCTCCAGCAAATAAGAAGGAATCTTGCTCACCAGCAGCATGGTGTC
ACGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAGAAAAAGGAAAGAGAGCTGCTCCCCTTACTGCATGCTGCCTGG
GACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGGCTACAGTATACTCAGAAGAGGCGGTACAAGCAGCTGCTACAGGCC
AGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCACACATGGAACAGACTCTGGCGATGGCGCCACCAGGAAAATGTC
CTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCACCTTCGGGATGAACGGGACATATGTTTTCAGAAAAATAAGGCAGCC
AAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGCTCTGTGATAGGCAAATATGTGGACAGCAGAGGGATTCTTAGG
AGCCAGTCAGAGGAGGAGGAGGAGGTGTTTGGCATCCCAAGGAGAAGCTCCCTGGGCCTGAGTGGATATCCCCTAACAGAAGAGGAGCCA
GGAACCGGGGAGCCAGGGCCTGGGGGTCCGTACCCCCGGCCGCTCCGCAGAATCATCTCCGTTGAAGAAGACCCCCTGCCCCAGCTCCTG
GATGGTGGCTTTGAGCAACCCCTGAGCAAATGCTCAGAAGAGGAAGAGGTCTCTGACCAGGGGGTACAGGGACAAATCCCGGAGGCCCCA
CCCTTGAAACTCACCCCCACATCCCCCCGAGGGCAGCCTGTTGGAAAAGAAGCCCTGTGTAAGGAGGAAAGCTCTCCCTCTGCCCCTGAC
CGGCTCTTCAAGATTGTGTTCGTGGGCAATTCCGCGGTGGGGAAGACATCCTTCCTGAGGAGATTCTGTGAGGACCGGTTCTCCCCAGGC
ATGGCGGCCACTGTGGGCATTGATTACCGTGTGAAGACGTTGAATGTGGACAACTCTCAGGTGGCCCTGCAGCTGTGGGACACGGCTGGG
CAGGAGAGGTACCGGTGCATCACCCAGCAGTTCTTCAGAAAGGCAGATGGTGTCATCGTCATGTACGATCTCACAGACAAGCAGTCGTTC
CTGTCGGTCCGGCGGTGGCTGAGCAGCGTGGAGGAAGCTGTGGGAGACCGGGTGCCTGTTCTTCTGCTGGGTAATAAGCTTGACAACGAG
AAGGAGCGGGAAGTCCCCCGGGGCCTCGGAGAGCAGCTTGCCACGGAGAACAATCTGATCTTCTATGAATGCAGCGCCTACTCTGGTCAC
AACACCAAAGAGTCCCTGCTCCATCTGGCCAGGTTCCTCAAGGAGCAAGAAGACACAGTGAGAGAGGACACCATTCAGGTCGGCCACCCT

>81084_81084_1_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000400288_EFCAB4B_chr12_3753806_ENST00000440314_length(amino acids)=873AA_BP=513
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCTRQGRLRELRIRC
VARKFLYLWIRMTFGRVFPSKARFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKE
KQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
HYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRI
ALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRERNKHLRDERDICFQKNKAAKANTA
ASRASWKKRSGSVIGKYVDSRGILRSQSEEEEEVFGIPRRSSLGLSGYPLTEEEPGTGEPGPGGPYPRPLRRIISVEEDPLPQLLDGGFE
QPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEESSPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATV
GIDYRVKTLNVDNSQVALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDNEKEREV

--------------------------------------------------------------
>81084_81084_2_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000400288_EFCAB4B_chr12_3753806_ENST00000444507_length(transcript)=2187nt_BP=1649nt
AAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCCCAGTTAGAAGGGGAAGAT
AAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTGATTAAGCAGAGAATGGAG
AAGAAGGTTGATTCCAGGTATTTTAAGGATGGTGCAGTTAAGAAACCTTATTCTGCAAAGACACTGTCCAACAAGAAGTCTTCTGCATCC
TTTGGGATCCGGAGGGAGTTACCTAGTACCAGTCATCTAGTGCAGTATCGTGGCACACATACTTGTACCCGACAGGGCCGGTTAAGAGAA
CTGCGCATCAGATGCGTGGCCAGAAAGTTCTTATATTTATGGATTCGAATGACTTTTGGAAGAGTATTTCCCTCTAAAGCCAGATTTTAC
TATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAGTGGTGGGTTTTCCAGCACGAGTGGAAACTCTGTGTTCGAGCT
GACTGTCACTACAGGTATTACCTGTACAACCTGATGTTCCAGACGTGGAAGACCTATGTGCGTCAGCAGCAGGAGATGAGGAACAAGTAC
ATTAGAGCCGAGGTTCATGATGCAAAGCAAAAGATGCGACAGGCCTGGAAGTCCTGGTTGATCTACGTGGTTGTTCGTAGGACCAAACTT
CAGATGCAGACTACAGCTCTGGAGTTTAGGCAACGGATTATCTTACGGGTGTGGTGGAGCACGTGGAGGCAGCGACTAGGACAGGTCCGT
GTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGCCTCCAGGTGCAGGCTTGGTCACAGTGGCGGGAACAGCTCCTG
TATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACATCATCAGCACTGGCAAAAACGGAGATTTCTAAAGGCCTGGCTTGAA
TACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAGCGATTCCATCATGTCACTGTGCTCCAGATATACTTCTGTGAC
TGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCCCAGGTGGAGAAACTGGCCAGGAAGATGGCCCTGCGGCGCGCC
TTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCTGCCCAGTTTGAGATGGCAGAAGAGCACCACAGGCACAGCCAGCTG
TATTTTTGCTTTAGAGCCCTAAAAGACAATGTGACCCACGCTCATCTCCAGCAAATAAGAAGGAATCTTGCTCACCAGCAGCATGGTGTC
ACGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAGAAAAAGGAAAGAGAGCTGCTCCCCTTACTGCATGCTGCCTGG
GACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGGCTACAGTATACTCAGAAGAGGCGGTACAAGCAGCTGCTACAGGCC
AGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCACACATGGAACAGACTCTGGCGATGGCGCCACCAGGAAAATGTC
CTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCACCTTCGGGATGAACGGGACATATGTTTTCAGAAAAATAAGGCAGCC
AAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGCTCTGTGATAGGCAAATATGTGGACAGCAGAGGGATTCTTAGG
AGATGGCCACAGAGAGATAGAGGCATCCCGACTCTTCAGTATCAGACCCAGAGAGACCTTGAAGACTGCAAGCATGAAATGAAAAAGATA
TGCAAAGCGGAAGTGACTCTGGAGATGTAAATCAGCTCATCAGTAAAACCTTTGGGCCTGATCATCATGAATTCTTGTTCTAAATAGCTG
AATAATGAGATACAATTTGGGAGCCAAATCTCTGCAATAGTGGTTGGCCTGTTGGTTCCTCAGAATGGAATGGATTGATTGATTGATTCA
GCAGACGTTTACTGATTACCTACTGTGTACCAGACATTCTTTTGAGTTCTGTAAAGCCTCCAAAAATAAATTAGACATGAGGTCCTACCA

>81084_81084_2_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000400288_EFCAB4B_chr12_3753806_ENST00000444507_length(amino acids)=604AA_BP=513
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCTRQGRLRELRIRC
VARKFLYLWIRMTFGRVFPSKARFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKE
KQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
HYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRI
ALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRERNKHLRDERDICFQKNKAAKANTA

--------------------------------------------------------------
>81084_81084_3_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000400289_EFCAB4B_chr12_3753806_ENST00000440314_length(transcript)=2529nt_BP=1424nt
GGCGGGCGTGGACCGCGCGGGAGTTAAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCG
GCTTCCCCAGAAGGGGAAGATAAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAA
GTGATTAAGCAGAGAATGGAGAAGAAGGTTGATTCCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAG
GAGTGGTGGGTTTTCCAGCACGAGTGGAAACTCTGTGTTCGAGCTGACTGTCACTACAGGTATTACCTGTACAACCTGATGTTCCAGACG
TGGAAGACCTATGTGCGTCAGCAGCAGGAGATGAGGAACAAGTACATTAGAGCCGAGGTTCATGATGCAAAGCAAAAGATGCGACAGGCC
TGGAAGTCCTGGTTGATCTACGTGGTTGTTCGTAGGACCAAACTTCAGATGCAGACTACAGCTCTGGAGTTTAGGCAACGGATTATCTTA
CGGGTGTGGTGGAGCACGTGGAGGCAGCGACTAGGACAGGTCCGTGTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTG
AGCCTCCAGGTGCAGGCTTGGTCACAGTGGCGGGAACAGCTCCTGTATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACAT
CATCAGCACTGGCAAAAACGGAGATTTCTAAAGGCCTGGCTTGAATACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCT
GAGCGATTCCATCATGTCACTGTGCTCCAGATATACTTCTGTGACTGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCAT
GCCCAGGTGGAGAAACTGGCCAGGAAGATGGCCCTGCGGCGCGCCTTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCT
GCCCAGTTTGAGATGGCAGAAGAGCACCACAGGCACAGCCAGCTGTATTTTTGCTTTAGAGCCCTAAAAGACAATGTGACCCACGCTCAT
CTCCAGCAAATAAGAAGGAATCTTGCTCACCAGCAGCATGGTGTCACGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAG
CAGAAAAAGGAAAGAGAGCTGCTCCCCTTACTGCATGCTGCCTGGGACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGG
CTACAGTATACTCAGAAGAGGCGGTACAAGCAGCTGCTACAGGCCAGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTC
CACACATGGAACAGACTCTGGCGATGGCGCCACCAGGAAAATGTCCTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCAC
CTTCGGGATGAACGGGACATATGTTTTCAGAAAAATAAGGCAGCCAAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCT
GGCTCTGTGATAGGCAAATATGTGGACAGCAGAGGGATTCTTAGGAGCCAGTCAGAGGAGGAGGAGGAGGTGTTTGGCATCCCAAGGAGA
AGCTCCCTGGGCCTGAGTGGATATCCCCTAACAGAAGAGGAGCCAGGAACCGGGGAGCCAGGGCCTGGGGGTCCGTACCCCCGGCCGCTC
CGCAGAATCATCTCCGTTGAAGAAGACCCCCTGCCCCAGCTCCTGGATGGTGGCTTTGAGCAACCCCTGAGCAAATGCTCAGAAGAGGAA
GAGGTCTCTGACCAGGGGGTACAGGGACAAATCCCGGAGGCCCCACCCTTGAAACTCACCCCCACATCCCCCCGAGGGCAGCCTGTTGGA
AAAGAAGCCCTGTGTAAGGAGGAAAGCTCTCCCTCTGCCCCTGACCGGCTCTTCAAGATTGTGTTCGTGGGCAATTCCGCGGTGGGGAAG
ACATCCTTCCTGAGGAGATTCTGTGAGGACCGGTTCTCCCCAGGCATGGCGGCCACTGTGGGCATTGATTACCGTGTGAAGACGTTGAAT
GTGGACAACTCTCAGGTGGCCCTGCAGCTGTGGGACACGGCTGGGCAGGAGAGGTACCGGTGCATCACCCAGCAGTTCTTCAGAAAGGCA
GATGGTGTCATCGTCATGTACGATCTCACAGACAAGCAGTCGTTCCTGTCGGTCCGGCGGTGGCTGAGCAGCGTGGAGGAAGCTGTGGGA
GACCGGGTGCCTGTTCTTCTGCTGGGTAATAAGCTTGACAACGAGAAGGAGCGGGAAGTCCCCCGGGGCCTCGGAGAGCAGCTTGCCACG
GAGAACAATCTGATCTTCTATGAATGCAGCGCCTACTCTGGTCACAACACCAAAGAGTCCCTGCTCCATCTGGCCAGGTTCCTCAAGGAG
CAAGAAGACACAGTGAGAGAGGACACCATTCAGGTCGGCCACCCTGCTAAGAAGAAATCCTGCTGTGGCTGATAGGGTCCTACAAGGACT

>81084_81084_3_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000400289_EFCAB4B_chr12_3753806_ENST00000440314_length(amino acids)=791AA_BP=431
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMR
NKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWRE
QLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMAL
RRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQIEQKKERELLPLLH
AAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRERNKHLRDERDICFQKN
KAAKANTAASRASWKKRSGSVIGKYVDSRGILRSQSEEEEEVFGIPRRSSLGLSGYPLTEEEPGTGEPGPGGPYPRPLRRIISVEEDPLP
QLLDGGFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEESSPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRF
SPGMAATVGIDYRVKTLNVDNSQVALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKL

--------------------------------------------------------------
>81084_81084_4_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000400289_EFCAB4B_chr12_3753806_ENST00000444507_length(transcript)=1962nt_BP=1424nt
GGCGGGCGTGGACCGCGCGGGAGTTAAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCG
GCTTCCCCAGAAGGGGAAGATAAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAA
GTGATTAAGCAGAGAATGGAGAAGAAGGTTGATTCCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAG
GAGTGGTGGGTTTTCCAGCACGAGTGGAAACTCTGTGTTCGAGCTGACTGTCACTACAGGTATTACCTGTACAACCTGATGTTCCAGACG
TGGAAGACCTATGTGCGTCAGCAGCAGGAGATGAGGAACAAGTACATTAGAGCCGAGGTTCATGATGCAAAGCAAAAGATGCGACAGGCC
TGGAAGTCCTGGTTGATCTACGTGGTTGTTCGTAGGACCAAACTTCAGATGCAGACTACAGCTCTGGAGTTTAGGCAACGGATTATCTTA
CGGGTGTGGTGGAGCACGTGGAGGCAGCGACTAGGACAGGTCCGTGTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTG
AGCCTCCAGGTGCAGGCTTGGTCACAGTGGCGGGAACAGCTCCTGTATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACAT
CATCAGCACTGGCAAAAACGGAGATTTCTAAAGGCCTGGCTTGAATACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCT
GAGCGATTCCATCATGTCACTGTGCTCCAGATATACTTCTGTGACTGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCAT
GCCCAGGTGGAGAAACTGGCCAGGAAGATGGCCCTGCGGCGCGCCTTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCT
GCCCAGTTTGAGATGGCAGAAGAGCACCACAGGCACAGCCAGCTGTATTTTTGCTTTAGAGCCCTAAAAGACAATGTGACCCACGCTCAT
CTCCAGCAAATAAGAAGGAATCTTGCTCACCAGCAGCATGGTGTCACGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAG
CAGAAAAAGGAAAGAGAGCTGCTCCCCTTACTGCATGCTGCCTGGGACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGG
CTACAGTATACTCAGAAGAGGCGGTACAAGCAGCTGCTACAGGCCAGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTC
CACACATGGAACAGACTCTGGCGATGGCGCCACCAGGAAAATGTCCTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCAC
CTTCGGGATGAACGGGACATATGTTTTCAGAAAAATAAGGCAGCCAAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCT
GGCTCTGTGATAGGCAAATATGTGGACAGCAGAGGGATTCTTAGGAGATGGCCACAGAGAGATAGAGGCATCCCGACTCTTCAGTATCAG
ACCCAGAGAGACCTTGAAGACTGCAAGCATGAAATGAAAAAGATATGCAAAGCGGAAGTGACTCTGGAGATGTAAATCAGCTCATCAGTA
AAACCTTTGGGCCTGATCATCATGAATTCTTGTTCTAAATAGCTGAATAATGAGATACAATTTGGGAGCCAAATCTCTGCAATAGTGGTT
GGCCTGTTGGTTCCTCAGAATGGAATGGATTGATTGATTGATTCAGCAGACGTTTACTGATTACCTACTGTGTACCAGACATTCTTTTGA

>81084_81084_4_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000400289_EFCAB4B_chr12_3753806_ENST00000444507_length(amino acids)=522AA_BP=431
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMR
NKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWRE
QLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMAL
RRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQIEQKKERELLPLLH
AAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRERNKHLRDERDICFQKN

--------------------------------------------------------------
>81084_81084_5_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000414585_EFCAB4B_chr12_3753806_ENST00000440314_length(transcript)=2583nt_BP=1478nt
AGCAAGCTGAGCTCAGAGCGAAGCTGGCGAGCCAAGGAGATAAAGAACCCTCGGTGGGGATGCCCAGAGGGTGCATGCTCCACGCCCCTC
GAAACCGATTCTCATTGCTGCTGCTGCAAAGCAACCCGAAGTGCGCCACCTACCCGACTGAGGCTGCGCAAGCCCCGGGGTCTGGGCGGG
GTGGTCCTCGTGCGCGCCGCGTCGCCGTGGAGACGAGGGCGGGCCCGCGCGAGACTGGCGTCTAGAGGCGCGCGAAGCGCTGAGGCGGGC
GTGGACCGCGCGGGAGTTAAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCC
CAGTTAGAAGGGGAAGATAAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTG
ATTAAGCAGAGAATGGAGAAGAAGGTTGATTCCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAG
TGGTGGGTTTTCCAGCACGAGTGGAAACTCTGTGTTCGAGCTGACTGTCACTACAGGGTGTGGTGGAGCACGTGGAGGCAGCGACTAGGA
CAGGTCCGTGTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGCCTCCAGGTGCAGGCTTGGTCACAGTGGCGGGAA
CAGCTCCTGTATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACATCATCAGCACTGGCAAAAACGGAGATTTCTAAAGGCC
TGGCTTGAATACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAGCGATTCCATCATGTCACTGTGCTCCAGATATAC
TTCTGTGACTGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCCCAGGTGGAGAAACTGGCCAGGAAGATGGCCCTG
CGGCGCGCCTTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCTGCCCAGTTTGAGATGGCAGAAGAGCACCACAGGCAC
AGCCAGCTGTATTTTTGCTTTAGAGCCCTAAAAGACAATGTGACCCACGCTCATCTCCAGCAAATAAGAAGGAATCTTGCTCACCAGCAG
CATGGTGTCACGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAGAAAAAGGAAAGAGAGCTGCTCCCCTTACTGCAT
GCTGCCTGGGACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGGCTACAGTATACTCAGAAGAGGCGGTACAAGCAGCTG
CTACAGGCCAGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCACACATGGAACAGACTCTGGCGATGGCGCCACCAG
GAAAATGTCCTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCACCTTCGGGATGAACGGGACATATGTTTTCAGAAAAAT
AAGGCAGCCAAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGCTCTGTGATAGGCAAATATGTGGACAGCAGAGGG
ATTCTTAGGAGCCAGTCAGAGGAGGAGGAGGAGGTGTTTGGCATCCCAAGGAGAAGCTCCCTGGGCCTGAGTGGATATCCCCTAACAGAA
GAGGAGCCAGGAACCGGGGAGCCAGGGCCTGGGGGTCCGTACCCCCGGCCGCTCCGCAGAATCATCTCCGTTGAAGAAGACCCCCTGCCC
CAGCTCCTGGATGGTGGCTTTGAGCAACCCCTGAGCAAATGCTCAGAAGAGGAAGAGGTCTCTGACCAGGGGGTACAGGGACAAATCCCG
GAGGCCCCACCCTTGAAACTCACCCCCACATCCCCCCGAGGGCAGCCTGTTGGAAAAGAAGCCCTGTGTAAGGAGGAAAGCTCTCCCTCT
GCCCCTGACCGGCTCTTCAAGATTGTGTTCGTGGGCAATTCCGCGGTGGGGAAGACATCCTTCCTGAGGAGATTCTGTGAGGACCGGTTC
TCCCCAGGCATGGCGGCCACTGTGGGCATTGATTACCGTGTGAAGACGTTGAATGTGGACAACTCTCAGGTGGCCCTGCAGCTGTGGGAC
ACGGCTGGGCAGGAGAGGTACCGGTGCATCACCCAGCAGTTCTTCAGAAAGGCAGATGGTGTCATCGTCATGTACGATCTCACAGACAAG
CAGTCGTTCCTGTCGGTCCGGCGGTGGCTGAGCAGCGTGGAGGAAGCTGTGGGAGACCGGGTGCCTGTTCTTCTGCTGGGTAATAAGCTT
GACAACGAGAAGGAGCGGGAAGTCCCCCGGGGCCTCGGAGAGCAGCTTGCCACGGAGAACAATCTGATCTTCTATGAATGCAGCGCCTAC
TCTGGTCACAACACCAAAGAGTCCCTGCTCCATCTGGCCAGGTTCCTCAAGGAGCAAGAAGACACAGTGAGAGAGGACACCATTCAGGTC

>81084_81084_5_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000414585_EFCAB4B_chr12_3753806_ENST00000440314_length(amino acids)=720AA_BP=360
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRVWWSTWRQRLGQVRVSRALHAS
ALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERR
ESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWN
LWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRF
HRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRGILRSQSEEEEEVFGIPRRSSLGLSGYPLTEEEPGTGEPGPG
GPYPRPLRRIISVEEDPLPQLLDGGFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEESSPSAPDRLFKIVFV
GNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLS
SVEEAVGDRVPVLLLGNKLDNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQVGHPAKKKSCCG

--------------------------------------------------------------
>81084_81084_6_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000414585_EFCAB4B_chr12_3753806_ENST00000444507_length(transcript)=2016nt_BP=1478nt
AGCAAGCTGAGCTCAGAGCGAAGCTGGCGAGCCAAGGAGATAAAGAACCCTCGGTGGGGATGCCCAGAGGGTGCATGCTCCACGCCCCTC
GAAACCGATTCTCATTGCTGCTGCTGCAAAGCAACCCGAAGTGCGCCACCTACCCGACTGAGGCTGCGCAAGCCCCGGGGTCTGGGCGGG
GTGGTCCTCGTGCGCGCCGCGTCGCCGTGGAGACGAGGGCGGGCCCGCGCGAGACTGGCGTCTAGAGGCGCGCGAAGCGCTGAGGCGGGC
GTGGACCGCGCGGGAGTTAAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCC
CAGTTAGAAGGGGAAGATAAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTG
ATTAAGCAGAGAATGGAGAAGAAGGTTGATTCCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAG
TGGTGGGTTTTCCAGCACGAGTGGAAACTCTGTGTTCGAGCTGACTGTCACTACAGGGTGTGGTGGAGCACGTGGAGGCAGCGACTAGGA
CAGGTCCGTGTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGCCTCCAGGTGCAGGCTTGGTCACAGTGGCGGGAA
CAGCTCCTGTATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACATCATCAGCACTGGCAAAAACGGAGATTTCTAAAGGCC
TGGCTTGAATACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAGCGATTCCATCATGTCACTGTGCTCCAGATATAC
TTCTGTGACTGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCCCAGGTGGAGAAACTGGCCAGGAAGATGGCCCTG
CGGCGCGCCTTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCTGCCCAGTTTGAGATGGCAGAAGAGCACCACAGGCAC
AGCCAGCTGTATTTTTGCTTTAGAGCCCTAAAAGACAATGTGACCCACGCTCATCTCCAGCAAATAAGAAGGAATCTTGCTCACCAGCAG
CATGGTGTCACGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAGAAAAAGGAAAGAGAGCTGCTCCCCTTACTGCAT
GCTGCCTGGGACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGGCTACAGTATACTCAGAAGAGGCGGTACAAGCAGCTG
CTACAGGCCAGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCACACATGGAACAGACTCTGGCGATGGCGCCACCAG
GAAAATGTCCTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCACCTTCGGGATGAACGGGACATATGTTTTCAGAAAAAT
AAGGCAGCCAAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGCTCTGTGATAGGCAAATATGTGGACAGCAGAGGG
ATTCTTAGGAGATGGCCACAGAGAGATAGAGGCATCCCGACTCTTCAGTATCAGACCCAGAGAGACCTTGAAGACTGCAAGCATGAAATG
AAAAAGATATGCAAAGCGGAAGTGACTCTGGAGATGTAAATCAGCTCATCAGTAAAACCTTTGGGCCTGATCATCATGAATTCTTGTTCT
AAATAGCTGAATAATGAGATACAATTTGGGAGCCAAATCTCTGCAATAGTGGTTGGCCTGTTGGTTCCTCAGAATGGAATGGATTGATTG
ATTGATTCAGCAGACGTTTACTGATTACCTACTGTGTACCAGACATTCTTTTGAGTTCTGTAAAGCCTCCAAAAATAAATTAGACATGAG

>81084_81084_6_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000414585_EFCAB4B_chr12_3753806_ENST00000444507_length(amino acids)=451AA_BP=360
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRVWWSTWRQRLGQVRVSRALHAS
ALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERR
ESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWN
LWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRF
HRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRGILRRWPQRDRGIPTLQYQTQRDLEDCKHEMKKICKAEVTLE

--------------------------------------------------------------
>81084_81084_7_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000432498_EFCAB4B_chr12_3753806_ENST00000440314_length(transcript)=2949nt_BP=1844nt
AGCAAGCTGAGCTCAGAGCGAAGCTGGCGAGCCAAGGAGATAAAGAACCCTCGGTGGGGATGCCCAGAGGGTGCATGCTCCACGCCCCTC
GAAACCGATTCTCATTGCTGCTGCTGCAAAGCAACCCGAAGTGCGCCACCTACCCGACTGAGGCTGCGCAAGCCCCGGGGTCTGGGCGGG
GTGGTCCTCGTGCGCGCCGCGTCGCCGTGGAGACGAGGGCGGGCCCGCGCGAGACTGGCGTCTAGAGGCGCGCGAAGCGCTGAGGCGGGC
GTGGACCGCGCGGGAGTTAAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCC
CAGTTAGAAGGGGAAGATAAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTG
ATTAAGCAGAGAATGGAGAAGAAGGTTGATTCCAGGTATTTTAAGGATGGTGCAGTTAAGAAACCTTATTCTGCAAAGACACTGTCCAAC
AAGAAGTCTTCTGCATCCTTTGGGATCCGGAGGGAGTTACCTAGTACCAGTCATCTAGTGCAGTATCGTGGCACACATACTTGTACCCGA
CAGGGCCGGTTAAGAGAACTGCGCATCAGATGCGTGGCCAGAAAGTTCTTATATTTATGGATTCGAATGACTTTTGGAAGAGTATTTCCC
TCTAAAGCCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAGTGGTGGGTTTTCCAGCACGAGTGG
AAACTCTGTGTTCGAGCTGACTGTCACTACAGGTATTACCTGTACAACCTGATGTTCCAGACGTGGAAGACCTATGTGCGTCAGCAGCAG
GAGATGAGGAACAAGTACATTAGAGCCGAGGTTCATGATGCAAAGCAAAAGATGCGACAGGCCTGGAAGTCCTGGTTGATCTACGTGGTT
GTTCGTAGGACCAAACTTCAGATGCAGACTACAGCTCTGGAGTTTAGGCAACGGATTATCTTACGGGTGTGGTGGAGCACGTGGAGGCAG
CGACTAGGACAGGTCCGTGTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGCCTCCAGGTGCAGGCTTGGTCACAG
TGGCGGGAACAGCTCCTGTATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACATCATCAGCACTGGCAAAAACGGAGATTT
CTAAAGGCCTGGCTTGAATACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAGCGATTCCATCATGTCACTGTGCTC
CAGATATACTTCTGTGACTGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCCCAGGTGGAGAAACTGGCCAGGAAG
ATGGCCCTGCGGCGCGCCTTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCTGCCCAGTTTGAGATGGCAGAAGAGCAC
CACAGGCACAGCCAGCTGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAGAAAAAGGAAAGAGAGCTGCTCCCCTTA
CTGCATGCTGCCTGGGACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGGCTACAGTATACTCAGAAGAGGCGGTACAAG
CAGCTGCTACAGGCCAGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCACACATGGAACAGACTCTGGCGATGGCGC
CACCAGGAAAATGTCCTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCACCTTCGGGATGAACGGGACATATGTTTTCAG
AAAAATAAGGCAGCCAAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGCTCTGTGATAGGCAAATATGTGGACAGC
AGAGGGATTCTTAGGAGCCAGTCAGAGGAGGAGGAGGAGGTGTTTGGCATCCCAAGGAGAAGCTCCCTGGGCCTGAGTGGATATCCCCTA
ACAGAAGAGGAGCCAGGAACCGGGGAGCCAGGGCCTGGGGGTCCGTACCCCCGGCCGCTCCGCAGAATCATCTCCGTTGAAGAAGACCCC
CTGCCCCAGCTCCTGGATGGTGGCTTTGAGCAACCCCTGAGCAAATGCTCAGAAGAGGAAGAGGTCTCTGACCAGGGGGTACAGGGACAA
ATCCCGGAGGCCCCACCCTTGAAACTCACCCCCACATCCCCCCGAGGGCAGCCTGTTGGAAAAGAAGCCCTGTGTAAGGAGGAAAGCTCT
CCCTCTGCCCCTGACCGGCTCTTCAAGATTGTGTTCGTGGGCAATTCCGCGGTGGGGAAGACATCCTTCCTGAGGAGATTCTGTGAGGAC
CGGTTCTCCCCAGGCATGGCGGCCACTGTGGGCATTGATTACCGTGTGAAGACGTTGAATGTGGACAACTCTCAGGTGGCCCTGCAGCTG
TGGGACACGGCTGGGCAGGAGAGGTACCGGTGCATCACCCAGCAGTTCTTCAGAAAGGCAGATGGTGTCATCGTCATGTACGATCTCACA
GACAAGCAGTCGTTCCTGTCGGTCCGGCGGTGGCTGAGCAGCGTGGAGGAAGCTGTGGGAGACCGGGTGCCTGTTCTTCTGCTGGGTAAT
AAGCTTGACAACGAGAAGGAGCGGGAAGTCCCCCGGGGCCTCGGAGAGCAGCTTGCCACGGAGAACAATCTGATCTTCTATGAATGCAGC
GCCTACTCTGGTCACAACACCAAAGAGTCCCTGCTCCATCTGGCCAGGTTCCTCAAGGAGCAAGAAGACACAGTGAGAGAGGACACCATT

>81084_81084_7_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000432498_EFCAB4B_chr12_3753806_ENST00000440314_length(amino acids)=842AA_BP=482
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCTRQGRLRELRIRC
VARKFLYLWIRMTFGRVFPSKARFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKE
KQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHF
QQRALPAAFHTWNRLWRWRHQENVLSARATRFHRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRGILRSQSEEE
EEVFGIPRRSSLGLSGYPLTEEEPGTGEPGPGGPYPRPLRRIISVEEDPLPQLLDGGFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTP
TSPRGQPVGKEALCKEESSPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTAGQERYRC
ITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESL

--------------------------------------------------------------
>81084_81084_8_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000432498_EFCAB4B_chr12_3753806_ENST00000444507_length(transcript)=2382nt_BP=1844nt
AGCAAGCTGAGCTCAGAGCGAAGCTGGCGAGCCAAGGAGATAAAGAACCCTCGGTGGGGATGCCCAGAGGGTGCATGCTCCACGCCCCTC
GAAACCGATTCTCATTGCTGCTGCTGCAAAGCAACCCGAAGTGCGCCACCTACCCGACTGAGGCTGCGCAAGCCCCGGGGTCTGGGCGGG
GTGGTCCTCGTGCGCGCCGCGTCGCCGTGGAGACGAGGGCGGGCCCGCGCGAGACTGGCGTCTAGAGGCGCGCGAAGCGCTGAGGCGGGC
GTGGACCGCGCGGGAGTTAAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCC
CAGTTAGAAGGGGAAGATAAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTG
ATTAAGCAGAGAATGGAGAAGAAGGTTGATTCCAGGTATTTTAAGGATGGTGCAGTTAAGAAACCTTATTCTGCAAAGACACTGTCCAAC
AAGAAGTCTTCTGCATCCTTTGGGATCCGGAGGGAGTTACCTAGTACCAGTCATCTAGTGCAGTATCGTGGCACACATACTTGTACCCGA
CAGGGCCGGTTAAGAGAACTGCGCATCAGATGCGTGGCCAGAAAGTTCTTATATTTATGGATTCGAATGACTTTTGGAAGAGTATTTCCC
TCTAAAGCCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAGTGGTGGGTTTTCCAGCACGAGTGG
AAACTCTGTGTTCGAGCTGACTGTCACTACAGGTATTACCTGTACAACCTGATGTTCCAGACGTGGAAGACCTATGTGCGTCAGCAGCAG
GAGATGAGGAACAAGTACATTAGAGCCGAGGTTCATGATGCAAAGCAAAAGATGCGACAGGCCTGGAAGTCCTGGTTGATCTACGTGGTT
GTTCGTAGGACCAAACTTCAGATGCAGACTACAGCTCTGGAGTTTAGGCAACGGATTATCTTACGGGTGTGGTGGAGCACGTGGAGGCAG
CGACTAGGACAGGTCCGTGTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGCCTCCAGGTGCAGGCTTGGTCACAG
TGGCGGGAACAGCTCCTGTATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACATCATCAGCACTGGCAAAAACGGAGATTT
CTAAAGGCCTGGCTTGAATACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAGCGATTCCATCATGTCACTGTGCTC
CAGATATACTTCTGTGACTGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCCCAGGTGGAGAAACTGGCCAGGAAG
ATGGCCCTGCGGCGCGCCTTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCTGCCCAGTTTGAGATGGCAGAAGAGCAC
CACAGGCACAGCCAGCTGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAGAAAAAGGAAAGAGAGCTGCTCCCCTTA
CTGCATGCTGCCTGGGACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGGCTACAGTATACTCAGAAGAGGCGGTACAAG
CAGCTGCTACAGGCCAGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCACACATGGAACAGACTCTGGCGATGGCGC
CACCAGGAAAATGTCCTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCACCTTCGGGATGAACGGGACATATGTTTTCAG
AAAAATAAGGCAGCCAAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGCTCTGTGATAGGCAAATATGTGGACAGC
AGAGGGATTCTTAGGAGATGGCCACAGAGAGATAGAGGCATCCCGACTCTTCAGTATCAGACCCAGAGAGACCTTGAAGACTGCAAGCAT
GAAATGAAAAAGATATGCAAAGCGGAAGTGACTCTGGAGATGTAAATCAGCTCATCAGTAAAACCTTTGGGCCTGATCATCATGAATTCT
TGTTCTAAATAGCTGAATAATGAGATACAATTTGGGAGCCAAATCTCTGCAATAGTGGTTGGCCTGTTGGTTCCTCAGAATGGAATGGAT
TGATTGATTGATTCAGCAGACGTTTACTGATTACCTACTGTGTACCAGACATTCTTTTGAGTTCTGTAAAGCCTCCAAAAATAAATTAGA

>81084_81084_8_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000432498_EFCAB4B_chr12_3753806_ENST00000444507_length(amino acids)=573AA_BP=482
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCTRQGRLRELRIRC
VARKFLYLWIRMTFGRVFPSKARFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKE
KQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHF
QQRALPAAFHTWNRLWRWRHQENVLSARATRFHRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRGILRRWPQRD

--------------------------------------------------------------
>81084_81084_9_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000443011_EFCAB4B_chr12_3753806_ENST00000440314_length(transcript)=2471nt_BP=1366nt
GCTGCAAAGCAACCCGAAGTGCGCCACCTACCCGACTGAGGCTGCGCAAGCCCCGGGGTCTGGGCGGGGTGGTCCTCGTGCGCGCCGCGT
CGCCGTGGAGACGAGGGCGGGCCCGCGCGAGACTGGCGTCTAGAGGCGCGCGAAGCGCTGAGGCGGGCGTGGACCGCGCGGGAGTTAAGA
AGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCCCAGTTAGAAGGGGAAGATAAAA
GACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTGATTAAGCAGAGAATGGAGAAGA
AGGTTGATTCCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAGTGGTGGGTTTTCCAGCACGAGT
GGAAACTCTGTGTTCGAGCTGACTGTCACTACAGGGTGTGGTGGAGCACGTGGAGGCAGCGACTAGGACAGGTCCGTGTGAGCCGTGCCC
TCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGCCTCCAGGTGCAGGCTTGGTCACAGTGGCGGGAACAGCTCCTGTATGTCCAGAAGG
AGAAACAAAAGGTTGTCTCTGCAGTGAAACATCATCAGCACTGGCAAAAACGGAGATTTCTAAAGGCCTGGCTTGAATACCTGCAAGTCC
GCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAGCGATTCCATCATGTCACTGTGCTCCAGATATACTTCTGTGACTGGCAGCAGGCCT
GGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCCCAGGTGGAGAAACTGGCCAGGAAGATGGCCCTGCGGCGCGCCTTTACTCACTGGA
AACACTACATGCTGCTGTGTGCAGAAGAAGCTGCCCAGTTTGAGATGGCAGAAGAGCACCACAGGCACAGCCAGCTGTATTTTTGCTTTA
GAGCCCTAAAAGACAATGTGACCCACGCTCATCTCCAGCAAATAAGAAGGAATCTTGCTCACCAGCAGCATGGTGTCACGCTGCTGCACA
GGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAGAAAAAGGAAAGAGAGCTGCTCCCCTTACTGCATGCTGCCTGGGACCACTACAGAA
TAGCACTGCTGTGCAAATGTATCGAATTGTGGCTACAGTATACTCAGAAGAGGCGGTACAAGCAGCTGCTACAGGCCAGAGCGGATGGTC
ATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCACACATGGAACAGACTCTGGCGATGGCGCCACCAGGAAAATGTCCTCAGTGCAAGAG
CAACACGTTTCCACAGGGAAAGGAACAAGCACCTTCGGGATGAACGGGACATATGTTTTCAGAAAAATAAGGCAGCCAAGGCAAACACAG
CTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGCTCTGTGATAGGCAAATATGTGGACAGCAGAGGGATTCTTAGGAGCCAGTCAGAGG
AGGAGGAGGAGGTGTTTGGCATCCCAAGGAGAAGCTCCCTGGGCCTGAGTGGATATCCCCTAACAGAAGAGGAGCCAGGAACCGGGGAGC
CAGGGCCTGGGGGTCCGTACCCCCGGCCGCTCCGCAGAATCATCTCCGTTGAAGAAGACCCCCTGCCCCAGCTCCTGGATGGTGGCTTTG
AGCAACCCCTGAGCAAATGCTCAGAAGAGGAAGAGGTCTCTGACCAGGGGGTACAGGGACAAATCCCGGAGGCCCCACCCTTGAAACTCA
CCCCCACATCCCCCCGAGGGCAGCCTGTTGGAAAAGAAGCCCTGTGTAAGGAGGAAAGCTCTCCCTCTGCCCCTGACCGGCTCTTCAAGA
TTGTGTTCGTGGGCAATTCCGCGGTGGGGAAGACATCCTTCCTGAGGAGATTCTGTGAGGACCGGTTCTCCCCAGGCATGGCGGCCACTG
TGGGCATTGATTACCGTGTGAAGACGTTGAATGTGGACAACTCTCAGGTGGCCCTGCAGCTGTGGGACACGGCTGGGCAGGAGAGGTACC
GGTGCATCACCCAGCAGTTCTTCAGAAAGGCAGATGGTGTCATCGTCATGTACGATCTCACAGACAAGCAGTCGTTCCTGTCGGTCCGGC
GGTGGCTGAGCAGCGTGGAGGAAGCTGTGGGAGACCGGGTGCCTGTTCTTCTGCTGGGTAATAAGCTTGACAACGAGAAGGAGCGGGAAG
TCCCCCGGGGCCTCGGAGAGCAGCTTGCCACGGAGAACAATCTGATCTTCTATGAATGCAGCGCCTACTCTGGTCACAACACCAAAGAGT
CCCTGCTCCATCTGGCCAGGTTCCTCAAGGAGCAAGAAGACACAGTGAGAGAGGACACCATTCAGGTCGGCCACCCTGCTAAGAAGAAAT

>81084_81084_9_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000443011_EFCAB4B_chr12_3753806_ENST00000440314_length(amino acids)=720AA_BP=360
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRVWWSTWRQRLGQVRVSRALHAS
ALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERR
ESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWN
LWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRF
HRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRGILRSQSEEEEEVFGIPRRSSLGLSGYPLTEEEPGTGEPGPG
GPYPRPLRRIISVEEDPLPQLLDGGFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEESSPSAPDRLFKIVFV
GNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLS
SVEEAVGDRVPVLLLGNKLDNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQVGHPAKKKSCCG

--------------------------------------------------------------
>81084_81084_10_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000443011_EFCAB4B_chr12_3753806_ENST00000444507_length(transcript)=1904nt_BP=1366nt
GCTGCAAAGCAACCCGAAGTGCGCCACCTACCCGACTGAGGCTGCGCAAGCCCCGGGGTCTGGGCGGGGTGGTCCTCGTGCGCGCCGCGT
CGCCGTGGAGACGAGGGCGGGCCCGCGCGAGACTGGCGTCTAGAGGCGCGCGAAGCGCTGAGGCGGGCGTGGACCGCGCGGGAGTTAAGA
AGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCCCAGTTAGAAGGGGAAGATAAAA
GACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTGATTAAGCAGAGAATGGAGAAGA
AGGTTGATTCCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAGTGGTGGGTTTTCCAGCACGAGT
GGAAACTCTGTGTTCGAGCTGACTGTCACTACAGGGTGTGGTGGAGCACGTGGAGGCAGCGACTAGGACAGGTCCGTGTGAGCCGTGCCC
TCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGCCTCCAGGTGCAGGCTTGGTCACAGTGGCGGGAACAGCTCCTGTATGTCCAGAAGG
AGAAACAAAAGGTTGTCTCTGCAGTGAAACATCATCAGCACTGGCAAAAACGGAGATTTCTAAAGGCCTGGCTTGAATACCTGCAAGTCC
GCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAGCGATTCCATCATGTCACTGTGCTCCAGATATACTTCTGTGACTGGCAGCAGGCCT
GGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCCCAGGTGGAGAAACTGGCCAGGAAGATGGCCCTGCGGCGCGCCTTTACTCACTGGA
AACACTACATGCTGCTGTGTGCAGAAGAAGCTGCCCAGTTTGAGATGGCAGAAGAGCACCACAGGCACAGCCAGCTGTATTTTTGCTTTA
GAGCCCTAAAAGACAATGTGACCCACGCTCATCTCCAGCAAATAAGAAGGAATCTTGCTCACCAGCAGCATGGTGTCACGCTGCTGCACA
GGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAGAAAAAGGAAAGAGAGCTGCTCCCCTTACTGCATGCTGCCTGGGACCACTACAGAA
TAGCACTGCTGTGCAAATGTATCGAATTGTGGCTACAGTATACTCAGAAGAGGCGGTACAAGCAGCTGCTACAGGCCAGAGCGGATGGTC
ATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCACACATGGAACAGACTCTGGCGATGGCGCCACCAGGAAAATGTCCTCAGTGCAAGAG
CAACACGTTTCCACAGGGAAAGGAACAAGCACCTTCGGGATGAACGGGACATATGTTTTCAGAAAAATAAGGCAGCCAAGGCAAACACAG
CTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGCTCTGTGATAGGCAAATATGTGGACAGCAGAGGGATTCTTAGGAGATGGCCACAGA
GAGATAGAGGCATCCCGACTCTTCAGTATCAGACCCAGAGAGACCTTGAAGACTGCAAGCATGAAATGAAAAAGATATGCAAAGCGGAAG
TGACTCTGGAGATGTAAATCAGCTCATCAGTAAAACCTTTGGGCCTGATCATCATGAATTCTTGTTCTAAATAGCTGAATAATGAGATAC
AATTTGGGAGCCAAATCTCTGCAATAGTGGTTGGCCTGTTGGTTCCTCAGAATGGAATGGATTGATTGATTGATTCAGCAGACGTTTACT
GATTACCTACTGTGTACCAGACATTCTTTTGAGTTCTGTAAAGCCTCCAAAAATAAATTAGACATGAGGTCCTACCATTAATCTCCATTA

>81084_81084_10_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000443011_EFCAB4B_chr12_3753806_ENST00000444507_length(amino acids)=451AA_BP=360
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRVWWSTWRQRLGQVRVSRALHAS
ALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERR
ESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWN
LWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRF
HRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRGILRRWPQRDRGIPTLQYQTQRDLEDCKHEMKKICKAEVTLE

--------------------------------------------------------------
>81084_81084_11_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000443326_EFCAB4B_chr12_3753806_ENST00000440314_length(transcript)=2796nt_BP=1691nt
AGCAAGCTGAGCTCAGAGCGAAGCTGGCGAGCCAAGGAGATAAAGAACCCTCGGTGGGGATGCCCAGAGGGTGCATGCTCCACGCCCCTC
GAAACCGATTCTCATTGCTGCTGCTGCAAAGCAACCCGAAGTGCGCCACCTACCCGACTGAGGCTGCGCAAGCCCCGGGGTCTGGGCGGG
GTGGTCCTCGTGCGCGCCGCGTCGCCGTGGAGACGAGGGCGGGCCCGCGCGAGACTGGCGTCTAGAGGCGCGCGAAGCGCTGAGGCGGGC
GTGGACCGCGCGGGAGTTAAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCC
CAGTTAGAAGGGGAAGATAAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTG
ATTAAGCAGAGAATGGAGAAGAAGGTTGATTCCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAG
TGGTGGGTTTTCCAGCACGAGTGGAAACTCTGTGTTCGAGCTGACTGTCACTACAGGTATTACCTGTACAACCTGATGTTCCAGACGTGG
AAGACCTATGTGCGTCAGCAGCAGGAGATGAGGAACAAGTACATTAGAGCCGAGGTTCATGATGCAAAGCAAAAGATGCGACAGGCCTGG
AAGTCCTGGTTGATCTACGTGGTTGTTCGTAGGACCAAACTTCAGATGCAGACTACAGCTCTGGAGTTTAGGCAACGGATTATCTTACGG
GTGTGGTGGAGCACGTGGAGGCAGCGACTAGGACAGGTCCGTGTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGC
CTCCAGGTGCAGGCTTGGTCACAGTGGCGGGAACAGCTCCTGTATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACATCAT
CAGCACTGGCAAAAACGGAGATTTCTAAAGGCCTGGCTTGAATACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAG
CGATTCCATCATGTCACTGTGCTCCAGATATACTTCTGTGACTGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCC
CAGGTGGAGAAACTGGCCAGGAAGATGGCCCTGCGGCGCGCCTTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCTGCC
CAGTTTGAGATGGCAGAAGAGCACCACAGGCACAGCCAGCTGTATTTTTGCTTTAGAGCCCTAAAAGACAATGTGACCCACGCTCATCTC
CAGCAAATAAGAAGGAATCTTGCTCACCAGCAGCATGGTGTCACGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAG
AAAAAGGAAAGAGAGCTGCTCCCCTTACTGCATGCTGCCTGGGACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGGCTA
CAGTATACTCAGAAGAGGCGGTACAAGCAGCTGCTACAGGCCAGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCAC
ACATGGAACAGACTCTGGCGATGGCGCCACCAGGAAAATGTCCTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCACCTT
CGGGATGAACGGGACATATGTTTTCAGAAAAATAAGGCAGCCAAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGC
TCTGTGATAGGCAAATATGTGGACAGCAGAGGGATTCTTAGGAGCCAGTCAGAGGAGGAGGAGGAGGTGTTTGGCATCCCAAGGAGAAGC
TCCCTGGGCCTGAGTGGATATCCCCTAACAGAAGAGGAGCCAGGAACCGGGGAGCCAGGGCCTGGGGGTCCGTACCCCCGGCCGCTCCGC
AGAATCATCTCCGTTGAAGAAGACCCCCTGCCCCAGCTCCTGGATGGTGGCTTTGAGCAACCCCTGAGCAAATGCTCAGAAGAGGAAGAG
GTCTCTGACCAGGGGGTACAGGGACAAATCCCGGAGGCCCCACCCTTGAAACTCACCCCCACATCCCCCCGAGGGCAGCCTGTTGGAAAA
GAAGCCCTGTGTAAGGAGGAAAGCTCTCCCTCTGCCCCTGACCGGCTCTTCAAGATTGTGTTCGTGGGCAATTCCGCGGTGGGGAAGACA
TCCTTCCTGAGGAGATTCTGTGAGGACCGGTTCTCCCCAGGCATGGCGGCCACTGTGGGCATTGATTACCGTGTGAAGACGTTGAATGTG
GACAACTCTCAGGTGGCCCTGCAGCTGTGGGACACGGCTGGGCAGGAGAGGTACCGGTGCATCACCCAGCAGTTCTTCAGAAAGGCAGAT
GGTGTCATCGTCATGTACGATCTCACAGACAAGCAGTCGTTCCTGTCGGTCCGGCGGTGGCTGAGCAGCGTGGAGGAAGCTGTGGGAGAC
CGGGTGCCTGTTCTTCTGCTGGGTAATAAGCTTGACAACGAGAAGGAGCGGGAAGTCCCCCGGGGCCTCGGAGAGCAGCTTGCCACGGAG
AACAATCTGATCTTCTATGAATGCAGCGCCTACTCTGGTCACAACACCAAAGAGTCCCTGCTCCATCTGGCCAGGTTCCTCAAGGAGCAA
GAAGACACAGTGAGAGAGGACACCATTCAGGTCGGCCACCCTGCTAAGAAGAAATCCTGCTGTGGCTGATAGGGTCCTACAAGGACTGCC

>81084_81084_11_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000443326_EFCAB4B_chr12_3753806_ENST00000440314_length(amino acids)=791AA_BP=431
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMR
NKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWRE
QLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMAL
RRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQIEQKKERELLPLLH
AAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRERNKHLRDERDICFQKN
KAAKANTAASRASWKKRSGSVIGKYVDSRGILRSQSEEEEEVFGIPRRSSLGLSGYPLTEEEPGTGEPGPGGPYPRPLRRIISVEEDPLP
QLLDGGFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEESSPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRF
SPGMAATVGIDYRVKTLNVDNSQVALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKL

--------------------------------------------------------------
>81084_81084_12_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000443326_EFCAB4B_chr12_3753806_ENST00000444507_length(transcript)=2229nt_BP=1691nt
AGCAAGCTGAGCTCAGAGCGAAGCTGGCGAGCCAAGGAGATAAAGAACCCTCGGTGGGGATGCCCAGAGGGTGCATGCTCCACGCCCCTC
GAAACCGATTCTCATTGCTGCTGCTGCAAAGCAACCCGAAGTGCGCCACCTACCCGACTGAGGCTGCGCAAGCCCCGGGGTCTGGGCGGG
GTGGTCCTCGTGCGCGCCGCGTCGCCGTGGAGACGAGGGCGGGCCCGCGCGAGACTGGCGTCTAGAGGCGCGCGAAGCGCTGAGGCGGGC
GTGGACCGCGCGGGAGTTAAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCC
CAGTTAGAAGGGGAAGATAAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTG
ATTAAGCAGAGAATGGAGAAGAAGGTTGATTCCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAG
TGGTGGGTTTTCCAGCACGAGTGGAAACTCTGTGTTCGAGCTGACTGTCACTACAGGTATTACCTGTACAACCTGATGTTCCAGACGTGG
AAGACCTATGTGCGTCAGCAGCAGGAGATGAGGAACAAGTACATTAGAGCCGAGGTTCATGATGCAAAGCAAAAGATGCGACAGGCCTGG
AAGTCCTGGTTGATCTACGTGGTTGTTCGTAGGACCAAACTTCAGATGCAGACTACAGCTCTGGAGTTTAGGCAACGGATTATCTTACGG
GTGTGGTGGAGCACGTGGAGGCAGCGACTAGGACAGGTCCGTGTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGC
CTCCAGGTGCAGGCTTGGTCACAGTGGCGGGAACAGCTCCTGTATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACATCAT
CAGCACTGGCAAAAACGGAGATTTCTAAAGGCCTGGCTTGAATACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAG
CGATTCCATCATGTCACTGTGCTCCAGATATACTTCTGTGACTGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCC
CAGGTGGAGAAACTGGCCAGGAAGATGGCCCTGCGGCGCGCCTTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCTGCC
CAGTTTGAGATGGCAGAAGAGCACCACAGGCACAGCCAGCTGTATTTTTGCTTTAGAGCCCTAAAAGACAATGTGACCCACGCTCATCTC
CAGCAAATAAGAAGGAATCTTGCTCACCAGCAGCATGGTGTCACGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAG
AAAAAGGAAAGAGAGCTGCTCCCCTTACTGCATGCTGCCTGGGACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGGCTA
CAGTATACTCAGAAGAGGCGGTACAAGCAGCTGCTACAGGCCAGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCAC
ACATGGAACAGACTCTGGCGATGGCGCCACCAGGAAAATGTCCTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCACCTT
CGGGATGAACGGGACATATGTTTTCAGAAAAATAAGGCAGCCAAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGC
TCTGTGATAGGCAAATATGTGGACAGCAGAGGGATTCTTAGGAGATGGCCACAGAGAGATAGAGGCATCCCGACTCTTCAGTATCAGACC
CAGAGAGACCTTGAAGACTGCAAGCATGAAATGAAAAAGATATGCAAAGCGGAAGTGACTCTGGAGATGTAAATCAGCTCATCAGTAAAA
CCTTTGGGCCTGATCATCATGAATTCTTGTTCTAAATAGCTGAATAATGAGATACAATTTGGGAGCCAAATCTCTGCAATAGTGGTTGGC
CTGTTGGTTCCTCAGAATGGAATGGATTGATTGATTGATTCAGCAGACGTTTACTGATTACCTACTGTGTACCAGACATTCTTTTGAGTT

>81084_81084_12_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000443326_EFCAB4B_chr12_3753806_ENST00000444507_length(amino acids)=522AA_BP=431
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMR
NKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWRE
QLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMAL
RRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQIEQKKERELLPLLH
AAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRERNKHLRDERDICFQKN

--------------------------------------------------------------
>81084_81084_13_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000540643_EFCAB4B_chr12_3753806_ENST00000440314_length(transcript)=2877nt_BP=1772nt
AGCAAGCTGAGCTCAGAGCGAAGCTGGCGAGCCAAGGAGATAAAGAACCCTCGGTGGGGATGCCCAGAGGGTGCATGCTCCACGCCCCTC
GAAACCGATTCTCATTGCTGCTGCTGCAAAGCAACCCGAAGTGCGCCACCTACCCGACTGAGGCTGCGCAAGCCCCGGGGTCTGGGCGGG
GTGGTCCTCGTGCGCGCCGCGTCGCCGTGGAGACGAGGGCGGGCCCGCGCGAGACTGGCGTCTAGAGGCGCGCGAAGCGCTGAGGCGGGC
GTGGACCGCGCGGGAGTTAAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCC
CAGTTAGAAGGGGAAGATAAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTG
ATTAAGCAGAGAATGGAGAAGAAGGTTGATTCCAGGTATTTTAAGGATGGTGCAGTTAAGAAACCTTATTCTGCAAAGACACTGTCCAAC
AAGAAGTCTTCTGCATCCTTTGGGATCCGGAGGGAGTTACCTAGTACCAGTCATCTAGTGCAGTATCGTGGCACACATACTTGTACCCGA
CAGGGCCGGTTAAGAGAACTGCGCATCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAGTGGTGG
GTTTTCCAGCACGAGTGGAAACTCTGTGTTCGAGCTGACTGTCACTACAGGTATTACCTGTACAACCTGATGTTCCAGACGTGGAAGACC
TATGTGCGTCAGCAGCAGGAGATGAGGAACAAGTACATTAGAGCCGAGGTTCATGATGCAAAGCAAAAGATGCGACAGGCCTGGAAGTCC
TGGTTGATCTACGTGGTTGTTCGTAGGACCAAACTTCAGATGCAGACTACAGCTCTGGAGTTTAGGCAACGGATTATCTTACGGGTGTGG
TGGAGCACGTGGAGGCAGCGACTAGGACAGGTCCGTGTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGCCTCCAG
GTGCAGGCTTGGTCACAGTGGCGGGAACAGCTCCTGTATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACATCATCAGCAC
TGGCAAAAACGGAGATTTCTAAAGGCCTGGCTTGAATACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAGCGATTC
CATCATGTCACTGTGCTCCAGATATACTTCTGTGACTGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCCCAGGTG
GAGAAACTGGCCAGGAAGATGGCCCTGCGGCGCGCCTTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCTGCCCAGTTT
GAGATGGCAGAAGAGCACCACAGGCACAGCCAGCTGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAGAAAAAGGAA
AGAGAGCTGCTCCCCTTACTGCATGCTGCCTGGGACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGGCTACAGTATACT
CAGAAGAGGCGGTACAAGCAGCTGCTACAGGCCAGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCACACATGGAAC
AGACTCTGGCGATGGCGCCACCAGGAAAATGTCCTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCACCTTCGGGATGAA
CGGGACATATGTTTTCAGAAAAATAAGGCAGCCAAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGCTCTGTGATA
GGCAAATATGTGGACAGCAGAGGGATTCTTAGGAGCCAGTCAGAGGAGGAGGAGGAGGTGTTTGGCATCCCAAGGAGAAGCTCCCTGGGC
CTGAGTGGATATCCCCTAACAGAAGAGGAGCCAGGAACCGGGGAGCCAGGGCCTGGGGGTCCGTACCCCCGGCCGCTCCGCAGAATCATC
TCCGTTGAAGAAGACCCCCTGCCCCAGCTCCTGGATGGTGGCTTTGAGCAACCCCTGAGCAAATGCTCAGAAGAGGAAGAGGTCTCTGAC
CAGGGGGTACAGGGACAAATCCCGGAGGCCCCACCCTTGAAACTCACCCCCACATCCCCCCGAGGGCAGCCTGTTGGAAAAGAAGCCCTG
TGTAAGGAGGAAAGCTCTCCCTCTGCCCCTGACCGGCTCTTCAAGATTGTGTTCGTGGGCAATTCCGCGGTGGGGAAGACATCCTTCCTG
AGGAGATTCTGTGAGGACCGGTTCTCCCCAGGCATGGCGGCCACTGTGGGCATTGATTACCGTGTGAAGACGTTGAATGTGGACAACTCT
CAGGTGGCCCTGCAGCTGTGGGACACGGCTGGGCAGGAGAGGTACCGGTGCATCACCCAGCAGTTCTTCAGAAAGGCAGATGGTGTCATC
GTCATGTACGATCTCACAGACAAGCAGTCGTTCCTGTCGGTCCGGCGGTGGCTGAGCAGCGTGGAGGAAGCTGTGGGAGACCGGGTGCCT
GTTCTTCTGCTGGGTAATAAGCTTGACAACGAGAAGGAGCGGGAAGTCCCCCGGGGCCTCGGAGAGCAGCTTGCCACGGAGAACAATCTG
ATCTTCTATGAATGCAGCGCCTACTCTGGTCACAACACCAAAGAGTCCCTGCTCCATCTGGCCAGGTTCCTCAAGGAGCAAGAAGACACA

>81084_81084_13_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000540643_EFCAB4B_chr12_3753806_ENST00000440314_length(amino acids)=818AA_BP=458
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCTRQGRLRELRIRF
YYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTK
LQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWL
EYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQ
LLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENV
LSARATRFHRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRGILRSQSEEEEEVFGIPRRSSLGLSGYPLTEEEP
GTGEPGPGGPYPRPLRRIISVEEDPLPQLLDGGFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEESSPSAPD
RLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSF
LSVRRWLSSVEEAVGDRVPVLLLGNKLDNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQVGHP

--------------------------------------------------------------
>81084_81084_14_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000540643_EFCAB4B_chr12_3753806_ENST00000444507_length(transcript)=2310nt_BP=1772nt
AGCAAGCTGAGCTCAGAGCGAAGCTGGCGAGCCAAGGAGATAAAGAACCCTCGGTGGGGATGCCCAGAGGGTGCATGCTCCACGCCCCTC
GAAACCGATTCTCATTGCTGCTGCTGCAAAGCAACCCGAAGTGCGCCACCTACCCGACTGAGGCTGCGCAAGCCCCGGGGTCTGGGCGGG
GTGGTCCTCGTGCGCGCCGCGTCGCCGTGGAGACGAGGGCGGGCCCGCGCGAGACTGGCGTCTAGAGGCGCGCGAAGCGCTGAGGCGGGC
GTGGACCGCGCGGGAGTTAAGAAGCAGGTCCCGGATCGCCGTATACCGCCGGGTTTTCTCCCAACGTCAGGCCCGATGGCTCGGCTTCCC
CAGTTAGAAGGGGAAGATAAAAGACTTTGATTCATGAAGAATCTGCTCACTGAGAAGTGTATATCAAGCCACAATTTCCATCAAAAAGTG
ATTAAGCAGAGAATGGAGAAGAAGGTTGATTCCAGGTATTTTAAGGATGGTGCAGTTAAGAAACCTTATTCTGCAAAGACACTGTCCAAC
AAGAAGTCTTCTGCATCCTTTGGGATCCGGAGGGAGTTACCTAGTACCAGTCATCTAGTGCAGTATCGTGGCACACATACTTGTACCCGA
CAGGGCCGGTTAAGAGAACTGCGCATCAGATTTTACTATGAGCAGCGATTACTACGGAAGGTCTTCGAAGAATGGAAAGAGGAGTGGTGG
GTTTTCCAGCACGAGTGGAAACTCTGTGTTCGAGCTGACTGTCACTACAGGTATTACCTGTACAACCTGATGTTCCAGACGTGGAAGACC
TATGTGCGTCAGCAGCAGGAGATGAGGAACAAGTACATTAGAGCCGAGGTTCATGATGCAAAGCAAAAGATGCGACAGGCCTGGAAGTCC
TGGTTGATCTACGTGGTTGTTCGTAGGACCAAACTTCAGATGCAGACTACAGCTCTGGAGTTTAGGCAACGGATTATCTTACGGGTGTGG
TGGAGCACGTGGAGGCAGCGACTAGGACAGGTCCGTGTGAGCCGTGCCCTCCATGCCTCTGCTTTGAAGCACAGGGCCCTGAGCCTCCAG
GTGCAGGCTTGGTCACAGTGGCGGGAACAGCTCCTGTATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACATCATCAGCAC
TGGCAAAAACGGAGATTTCTAAAGGCCTGGCTTGAATACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGAGATGGCTGAGCGATTC
CATCATGTCACTGTGCTCCAGATATACTTCTGTGACTGGCAGCAGGCCTGGGAGCGGAGGGAGAGCTTGTACGCTCACCATGCCCAGGTG
GAGAAACTGGCCAGGAAGATGGCCCTGCGGCGCGCCTTTACTCACTGGAAACACTACATGCTGCTGTGTGCAGAAGAAGCTGCCCAGTTT
GAGATGGCAGAAGAGCACCACAGGCACAGCCAGCTGCTGCTGCACAGGTTCTGGAACCTCTGGCGGTCTCAGATTGAGCAGAAAAAGGAA
AGAGAGCTGCTCCCCTTACTGCATGCTGCCTGGGACCACTACAGAATAGCACTGCTGTGCAAATGTATCGAATTGTGGCTACAGTATACT
CAGAAGAGGCGGTACAAGCAGCTGCTACAGGCCAGAGCGGATGGTCATTTCCAGCAGAGAGCCCTGCCTGCTGCCTTCCACACATGGAAC
AGACTCTGGCGATGGCGCCACCAGGAAAATGTCCTCAGTGCAAGAGCAACACGTTTCCACAGGGAAAGGAACAAGCACCTTCGGGATGAA
CGGGACATATGTTTTCAGAAAAATAAGGCAGCCAAGGCAAACACAGCTGCTTCCAGGGCAAGTTGGAAAAAGAGATCTGGCTCTGTGATA
GGCAAATATGTGGACAGCAGAGGGATTCTTAGGAGATGGCCACAGAGAGATAGAGGCATCCCGACTCTTCAGTATCAGACCCAGAGAGAC
CTTGAAGACTGCAAGCATGAAATGAAAAAGATATGCAAAGCGGAAGTGACTCTGGAGATGTAAATCAGCTCATCAGTAAAACCTTTGGGC
CTGATCATCATGAATTCTTGTTCTAAATAGCTGAATAATGAGATACAATTTGGGAGCCAAATCTCTGCAATAGTGGTTGGCCTGTTGGTT
CCTCAGAATGGAATGGATTGATTGATTGATTCAGCAGACGTTTACTGATTACCTACTGTGTACCAGACATTCTTTTGAGTTCTGTAAAGC

>81084_81084_14_SFI1-EFCAB4B_SFI1_chr22_31985563_ENST00000540643_EFCAB4B_chr12_3753806_ENST00000444507_length(amino acids)=549AA_BP=458
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCTRQGRLRELRIRF
YYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTK
LQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWL
EYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQ
LLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENV
LSARATRFHRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRGILRRWPQRDRGIPTLQYQTQRDLEDCKHEMKKI

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Top

Fusion Gene PPI Analysis for SFI1-EFCAB4B

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000400288	-	15	33	111_130	514.6666666666666	1243.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000400288	-	15	33	475_494	514.6666666666666	1243.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000400289	-	13	31	111_130	432.6666666666667	1161.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000414585	-	11	29	111_130	361.6666666666667	989.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000432498	-	14	32	111_130	483.6666666666667	1212.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000443326	-	13	31	111_130	432.6666666666667	1161.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000540643	-	13	31	111_130	459.6666666666667	1188.0	CETN2

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000400288	-	15	33	641_660	514.6666666666666	1243.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000400289	-	13	31	475_494	432.6666666666667	1161.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000400289	-	13	31	641_660	432.6666666666667	1161.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000414585	-	11	29	475_494	361.6666666666667	989.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000414585	-	11	29	641_660	361.6666666666667	989.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000432498	-	14	32	475_494	483.6666666666667	1212.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000432498	-	14	32	641_660	483.6666666666667	1212.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000443326	-	13	31	475_494	432.6666666666667	1161.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000443326	-	13	31	641_660	432.6666666666667	1161.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000540643	-	13	31	475_494	459.6666666666667	1188.0	CETN2
Hgene	SFI1	chr22:31985563	chr12:3753806	ENST00000540643	-	13	31	641_660	459.6666666666667	1188.0	CETN2

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for SFI1-EFCAB4B

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for SFI1-EFCAB4B

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source