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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SFMBT1-RFT1 (FusionGDB2 ID:81100)

Fusion Gene Summary for SFMBT1-RFT1

check button Fusion gene summary
Fusion gene informationFusion gene name: SFMBT1-RFT1
Fusion gene ID: 81100
HgeneTgene
Gene symbol

SFMBT1

RFT1

Gene ID

51460

91869

Gene nameScm like with four mbt domains 1RFT1 homolog
SynonymsRU1|SFMBT|hSFMBTCDG1N
Cytomap

3p21.1

3p21.1

Type of geneprotein-codingprotein-coding
Descriptionscm-like with four MBT domains protein 1Scm-related gene containing four mbt domainsScm-related gene product containing four mbt domainsrenal ubiquitous protein 1protein RFT1 homologRFT1, requiring fifty three 1 homologcongenital disorder of glycosylation 1Nputative endoplasmic reticulum multispan transmembrane protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000296295, ENST00000358080, 
ENST00000394750, ENST00000394752, 
ENST00000470575, 		ENST00000296292, 
ENST00000394738, 
Fusion gene scores* DoF score18 X 15 X 11=29705 X 6 X 3=90
# samples 228
** MAII scorelog2(22/2970*10)=-3.75488750216347
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/90*10)=-0.169925001442312
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SFMBT1 [Title/Abstract] AND RFT1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSFMBT1(52977369)-RFT1(53133502), # samples:2
Anticipated loss of major functional domain due to fusion event.SFMBT1-RFT1 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
SFMBT1-RFT1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
SFMBT1-RFT1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
SFMBT1-RFT1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSFMBT1

GO:0045892

negative regulation of transcription, DNA-templated

23592795


check buttonFusion gene breakpoints across SFMBT1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RFT1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A4S3-01ASFMBT1chr3

53077152

-RFT1chr3

53160010

-
ChimerDB4BRCATCGA-A8-A07L-01ASFMBT1chr3

53079832

-RFT1chr3

53140885

-
ChimerDB4BRCATCGA-A8-A07L-01ASFMBT1chr3

53080476

-RFT1chr3

53140885

-
ChimerDB4LIHCTCGA-XR-A8TG-01ASFMBT1chr3

52977369

-RFT1chr3

53133502

-


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Fusion Gene ORF analysis for SFMBT1-RFT1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000296295ENST00000296292SFMBT1chr3

53079832

-RFT1chr3

53140885

-
5UTR-3CDSENST00000296295ENST00000394738SFMBT1chr3

53079832

-RFT1chr3

53140885

-
5UTR-3CDSENST00000358080ENST00000296292SFMBT1chr3

53077152

-RFT1chr3

53160010

-
5UTR-3CDSENST00000358080ENST00000296292SFMBT1chr3

53079832

-RFT1chr3

53140885

-
5UTR-3CDSENST00000358080ENST00000394738SFMBT1chr3

53077152

-RFT1chr3

53160010

-
5UTR-3CDSENST00000358080ENST00000394738SFMBT1chr3

53079832

-RFT1chr3

53140885

-
5UTR-3CDSENST00000394750ENST00000296292SFMBT1chr3

53077152

-RFT1chr3

53160010

-
5UTR-3CDSENST00000394750ENST00000394738SFMBT1chr3

53077152

-RFT1chr3

53160010

-
5UTR-3CDSENST00000394752ENST00000296292SFMBT1chr3

53079832

-RFT1chr3

53140885

-
5UTR-3CDSENST00000394752ENST00000394738SFMBT1chr3

53079832

-RFT1chr3

53140885

-
5UTR-3CDSENST00000470575ENST00000296292SFMBT1chr3

53077152

-RFT1chr3

53160010

-
5UTR-3CDSENST00000470575ENST00000394738SFMBT1chr3

53077152

-RFT1chr3

53160010

-
Frame-shiftENST00000358080ENST00000296292SFMBT1chr3

52977369

-RFT1chr3

53133502

-
Frame-shiftENST00000358080ENST00000394738SFMBT1chr3

52977369

-RFT1chr3

53133502

-
Frame-shiftENST00000394750ENST00000296292SFMBT1chr3

52977369

-RFT1chr3

53133502

-
Frame-shiftENST00000394750ENST00000394738SFMBT1chr3

52977369

-RFT1chr3

53133502

-
In-frameENST00000296295ENST00000296292SFMBT1chr3

52977369

-RFT1chr3

53133502

-
In-frameENST00000296295ENST00000394738SFMBT1chr3

52977369

-RFT1chr3

53133502

-
In-frameENST00000394752ENST00000296292SFMBT1chr3

52977369

-RFT1chr3

53133502

-
In-frameENST00000394752ENST00000394738SFMBT1chr3

52977369

-RFT1chr3

53133502

-
intron-3CDSENST00000296295ENST00000296292SFMBT1chr3

53077152

-RFT1chr3

53160010

-
intron-3CDSENST00000296295ENST00000296292SFMBT1chr3

53080476

-RFT1chr3

53140885

-
intron-3CDSENST00000296295ENST00000394738SFMBT1chr3

53077152

-RFT1chr3

53160010

-
intron-3CDSENST00000296295ENST00000394738SFMBT1chr3

53080476

-RFT1chr3

53140885

-
intron-3CDSENST00000358080ENST00000296292SFMBT1chr3

53080476

-RFT1chr3

53140885

-
intron-3CDSENST00000358080ENST00000394738SFMBT1chr3

53080476

-RFT1chr3

53140885

-
intron-3CDSENST00000394750ENST00000296292SFMBT1chr3

53079832

-RFT1chr3

53140885

-
intron-3CDSENST00000394750ENST00000296292SFMBT1chr3

53080476

-RFT1chr3

53140885

-
intron-3CDSENST00000394750ENST00000394738SFMBT1chr3

53079832

-RFT1chr3

53140885

-
intron-3CDSENST00000394750ENST00000394738SFMBT1chr3

53080476

-RFT1chr3

53140885

-
intron-3CDSENST00000394752ENST00000296292SFMBT1chr3

53077152

-RFT1chr3

53160010

-
intron-3CDSENST00000394752ENST00000296292SFMBT1chr3

53080476

-RFT1chr3

53140885

-
intron-3CDSENST00000394752ENST00000394738SFMBT1chr3

53077152

-RFT1chr3

53160010

-
intron-3CDSENST00000394752ENST00000394738SFMBT1chr3

53080476

-RFT1chr3

53140885

-
intron-3CDSENST00000470575ENST00000296292SFMBT1chr3

53079832

-RFT1chr3

53140885

-
intron-3CDSENST00000470575ENST00000296292SFMBT1chr3

53080476

-RFT1chr3

53140885

-
intron-3CDSENST00000470575ENST00000296292SFMBT1chr3

52977369

-RFT1chr3

53133502

-
intron-3CDSENST00000470575ENST00000394738SFMBT1chr3

53079832

-RFT1chr3

53140885

-
intron-3CDSENST00000470575ENST00000394738SFMBT1chr3

53080476

-RFT1chr3

53140885

-
intron-3CDSENST00000470575ENST00000394738SFMBT1chr3

52977369

-RFT1chr3

53133502

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394752SFMBT1chr352977369-ENST00000296292RFT1chr353133502-46917473441270308
ENST00000394752SFMBT1chr352977369-ENST00000394738RFT1chr353133502-15097473441270308
ENST00000296295SFMBT1chr352977369-ENST00000296292RFT1chr353133502-46777333301256308
ENST00000296295SFMBT1chr352977369-ENST00000394738RFT1chr353133502-14957333301256308

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394752ENST00000296292SFMBT1chr352977369-RFT1chr353133502-0.0094887470.99051124
ENST00000394752ENST00000394738SFMBT1chr352977369-RFT1chr353133502-0.0115393370.98846066
ENST00000296295ENST00000296292SFMBT1chr352977369-RFT1chr353133502-0.0095193550.9904806
ENST00000296295ENST00000394738SFMBT1chr352977369-RFT1chr353133502-0.0115917450.98840827

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Fusion Genomic Features for SFMBT1-RFT1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SFMBT1-RFT1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:52977369/chr3:53133502)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000296295-42034_42121824.0RegionNote=Antigenic epitope
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000358080-52234_42121867.0RegionNote=Antigenic epitope
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394750-52234_42121867.0RegionNote=Antigenic epitope
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394752-42134_42121867.0RegionNote=Antigenic epitope
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000296295-42020_120121824.0RepeatNote=MBT 1
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000358080-52220_120121867.0RepeatNote=MBT 1
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394750-52220_120121867.0RepeatNote=MBT 1
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394752-42120_120121867.0RepeatNote=MBT 1
TgeneRFT1chr3:52977369chr3:53133502ENST00000296292913376_396367542.0TransmembraneHelical
TgeneRFT1chr3:52977369chr3:53133502ENST00000296292913404_423367542.0TransmembraneHelical
TgeneRFT1chr3:52977369chr3:53133502ENST00000296292913428_450367542.0TransmembraneHelical
TgeneRFT1chr3:52977369chr3:53133502ENST00000296292913470_490367542.0TransmembraneHelical
TgeneRFT1chr3:52977369chr3:53133502ENST00000296292913499_519367542.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000296295-420796_864121824.0DomainNote=SAM
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000358080-522796_864121867.0DomainNote=SAM
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394750-522796_864121867.0DomainNote=SAM
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394752-421796_864121867.0DomainNote=SAM
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000296295-420128_232121824.0RepeatNote=MBT 2
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000296295-420242_348121824.0RepeatNote=MBT 3
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000296295-420356_453121824.0RepeatNote=MBT 4
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000358080-522128_232121867.0RepeatNote=MBT 2
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000358080-522242_348121867.0RepeatNote=MBT 3
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000358080-522356_453121867.0RepeatNote=MBT 4
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394750-522128_232121867.0RepeatNote=MBT 2
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394750-522242_348121867.0RepeatNote=MBT 3
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394750-522356_453121867.0RepeatNote=MBT 4
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394752-421128_232121867.0RepeatNote=MBT 2
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394752-421242_348121867.0RepeatNote=MBT 3
HgeneSFMBT1chr3:52977369chr3:53133502ENST00000394752-421356_453121867.0RepeatNote=MBT 4
TgeneRFT1chr3:52977369chr3:53133502ENST00000296292913123_143367542.0TransmembraneHelical
TgeneRFT1chr3:52977369chr3:53133502ENST00000296292913155_174367542.0TransmembraneHelical
TgeneRFT1chr3:52977369chr3:53133502ENST0000029629291316_36367542.0TransmembraneHelical
TgeneRFT1chr3:52977369chr3:53133502ENST00000296292913187_207367542.0TransmembraneHelical
TgeneRFT1chr3:52977369chr3:53133502ENST00000296292913335_355367542.0TransmembraneHelical
TgeneRFT1chr3:52977369chr3:53133502ENST0000029629291342_62367542.0TransmembraneHelical
TgeneRFT1chr3:52977369chr3:53133502ENST0000029629291385_105367542.0TransmembraneHelical


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Fusion Gene Sequence for SFMBT1-RFT1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>81100_81100_1_SFMBT1-RFT1_SFMBT1_chr3_52977369_ENST00000296295_RFT1_chr3_53133502_ENST00000296292_length(transcript)=4677nt_BP=733nt
CGCGGAGCGCCGCCGCCGCCTCCGCCGGAGCGCGGGTGGAGGGGGGCGGGGAGAGCTGCCGGCCGCCCCGCTCCGCCGAACCCAGCAGGA
AGGAGGGCGCGAGCGGGCGAGCGCGGGCAGCACGGGAGGAAAAAGCTTCCGCGCGGGGGAGCGAAAAGACGGAAAGAAAGAAAGAAAACG
AGCGCGAGAGGGGGAAAAGCGAGCGATCGAGCGAGCGCGCGCGCGAAAACTCCGGGCAGCACTTTCATTTGGACCCGTGGATACCCATTG
AACAGATGCTTGAAACCTGCAAGTAATCTTCAGATCCTAGCAGAACCATAGGCCTTTCCTTTGTTTTGGGAGGATATAGCCTGCCTATAT
GCTGTGGAAATGAACGGGGAGCAGCAGCTTGATGCAGATGCCGGCTCTGGTATGGAAGAGGTAGAATTAAGCTGGGAAGATTATCTAGAA
GAAACAGGGTCCACAGCAGTTCCCTATGGGTCTTTTAAACATGTGGACACACGTTTGCAAAATGGATTTGCTCCTGGGATGAAGCTGGAG
GTGGCTGTGAGAACAGATCCTGAGACCTACTGGGTTGCCACCGTTATCACTACCTGTGAGCAGTTGCTCCTTCTCCGCTATGATGGCTAT
GGGGAGGATCGGAGAGCAGATTTCTGGTGTGACATCAGGAAGGCTGATCTCTACCCCATTGGGTGGTGTGAGCAGAATAAGAAGACCCTT
GAAGCCCCAGAAGGTCCTGTTTTGCTGCGTTCCTACTGTCTCTATGTTCTCCTGCTTGCCATCAATGGAGTGACAGAGTGTTTCACATTT
GCTGCCATGAGCAAAGAGGAGGTCGACAGGTACAATTTTGTGATGCTGGCCCTGTCCTCCTCATTCCTGGTGTTATCCTATCTCTTGACC
CGTTGGTGTGGCAGCGTGGGCTTCATCTTGGCCAACTGCTTTAACATGGGCATTCGGATCACGCAGAGCCTTTGCTTCATCCACCGCTAC
TACCGAAGGAGCCCCCACAGGCCCCTGGCTGGCCTGCACCTATCGCCAGTCCTGCTCGGGACATTTGCCCTCAGTGGTGGGGTTACTGCT
GTTTCGGAGGTATTCCTCTGCTGTGAGCAGGGCTGGCCAGCCAGACTGGCACACATTGCTGTGGGGGCCTTCTGTCTGGGAGCAACTCTC
GGGACAGCATTCCTCACAGAGACCAAGCTGATCCATTTCCTCAGGACTCAGTTAGGTGTGCCCAGACGCACTGACAAAATGACATGACTT
CAGGGAAGCCTGGACACCCGAGGCACCTGGACCAGCTATGGGTAGTTCTGTGGGTGGAACACATTCTGTGTAAGAGCCCCACTGAGGGCT
CTGCAGCGGAGTGACAGCAACCCCAGAGATGAGGCACCAGAGAGTGCCACTGCATGAGACACCTGTGACCATTCGAAGTCTGAAATGCGG
GGGGGGAGTTTCATTTTTAAGTGAAGACCAAAAGCCCTTTAAAAATAATAGTTTTTTATCATTTTATAGTAATCAGCATTTTCTCTTTTA
CTAATATACTCATTCCTTTTGCGTATGATTGGCCTTTGGAGCTACATGCTCCAACAAACTATATCTTAATTGTTAACTGTTAATAATTAT
CTGGCCCAGAAAAAGAGATGCAGTGATTTTACCCTTCACAGGAATATTGAACTTCTTCTGTAAAAGAGAGAGAGAAACCTCTCTCTCTCA
TGCACCACATGGAAACAGAGTGTGGCCCTGAAGTTGTGGCTTTCTTTGTGTCAAAACTGTGGTCTGAGTTTTTAGAGAAGGAAAAATGCT
ACTCAGTGAGAAATCCAAGAAATGAAACCAGGAAGGTTTTCAGATCACATTTCCCAGAGTGAGTTCGGGAGAATCTTGCCTGTCGTGATC
ACACTGTTCCCCGCCGCCCCAGGTCAGCACATACTTGACCCAGAGTGGGCTCTCAGGATTTGTTGATTGAAGGGTGGGTGAAAGCTGGCT
GGAGACTCCTGGCCTGGCCACCTGCAAGAGGCGGACTTTGAAGAAAACTGTGATCCAGTTGAGCCACTTTGTCCCTGAGGGGAATGCTGC
TTTGCAGCTTTCTGTAACTTCTCACATGGGAATTGCACTGGTGACAGATAAGGTTTAACAGATGTACTTTTTTATCCTCAGAATAAGACA
AGGCAAACTCTATATGGCTAGTATTACTGAGTCAGGTCCCTCCCGTTGACCCATTAATTCCAGCATTGATCAATACAACCAAATTCCAGC
CCCAGGACAAGAGTGGCAGGCATGGGGGCCTGGTACTCCAGGCTACAGTGTGAGCCCAGGTGTTCTGCACCTTGCAGCCTGCACACTGCA
GGTGAAATCATGAGCAGTGTTCTGGAGTGTGAAGTGTTTTTATTTTTTTGTTAATGTATTAATTCCTTTTAGATATTAACCCCCCTCAGA
ACTATATGCACAAACTATAACTTGGATGTTAATAATCCTGTCACTCAGTGCCCCAAACCTTCTGTGTCTACACCTAGAGAGAGGGCCAGT
AAGGGCAACTCCTATCATGCATTAAAATGCATGTATTTAAATCTGCTTGCCCAGAGCCAGTACCCAGGGGCTAAGGATTAAGACCTGTCA
GTACACCAAGACTGGGGCCCAGTCACCTGGCAGGTTTTTATCTACTCAGAGGGAGAATGCTTTGCACTAAGTGGGAGAAAAGCAGCTAAA
TGCAAGGTGTCCTGAGCAATTAGAGGACCTCCAAAGCATGGCCTCAGTCATGCCTTCATCGGGCAAGGTCAGGCCAGCTCAGAAAAATGG
ATGGTCCCATAGGGTCAAGTGGAGCACACACGGAAGGCAGTCCTCCTTCCCTCCCATGTCCTTTCTCTGTCCCTGGCATCCACAGAAAGG
GACCTTCAGTCCTCATGAGCTGCTTCTCTGCAGCTGCTGATCACCCTCCCGGAACCCTGCACCTATCCCGTGCCCACCTGACCCCAGACT
CAAGCATGATCCTCATTCTACCTGCCTCGGAATCACCTGGATTGCAAGTCAGAACATGGCTTCCCAGGACCCACTCCAGGCCTTCAGGGT
CTGTGTCTCCCAGGAGGAGGGCTCTGAGATTGGCTTTTCTGGCAAGCCCACGTGGCTTTGATGCCACCAAGGTTGGCATGCCCCATTGTC
TTCCTTCGTGACAGGCCCAGGACCATCATGCTCATGCTCACAGTGCCTGTTCTCTGCTCCAGGAACAGAGCTGCTGCTCTACAAGCAGCC
TTGTGACTCCGGGGTCTCTGGGAGCAGGACTCCCCAGGCTTGTGCTCTCTCAGCTTGAGAGAGGCTCTATGTCTGAAGGCAGTGCTCACT
CTCTCATCCCTCCCCTGCTGTTCGCCCAGTGCTGCTGTCAGGGCCAGCTCCTCTTGAAAGACAGCCAGCCGCAAAGGCAGCCCAGGGCTT
CTTCCGGTGTCCTGCTTCCCTGTATCTAGGGAGAGTTGTACATGTGGCTGCGTGTTTTCCCAGGACTAGCCCTGCCGCCTGGGCTGTCAG
CACTTTGGCAGCAGGTCCTCTGTGGTTCTCTGCCTCTGGTGCCTCCCTAAAGCTCAGCTGGACCTGACCAGGCCTCTGGCATTTCCCCTG
CTGGACCCCCTAGAGCCACAGCTGTGCCTCAGGGAGCTTGCATACATGTGGGCCAGCCTGCCTCACTTTACCCAAGTGGATTTGGGGAGC
AGAAATCATACTTTTGGCTTTCAATACCACTTATAGTGAGGCTACTTCTCCATGGAAACAAGTCTCTGAGGCACAACCTTTATGAAAGGA
AGGAGCATTCGTTGGTGAGAAGAACAGTATCGCTGACTTCCTGTGCTCCTCTGGCCACAGGTAACTGTTGGTCACTTCAGATTTGGCTTG
GGGTCTCTCAGTGAGGAGCTGCTGCTGTGCTGTTTAATGCTTACCTGATGGCAACTTCTGGCTCTGGAACCGCTACTCTGCCCTGTTCCC
AGCCACTTCCCAACCTGATTCAAGCAGGGCCCCTCCTTCCTCCTGTCTTTATTTATTTATTTATTGAGACAGAGTCTCACTCTGTCGCCC
AGGCTGGAGTGCAGTAGCGCGATCTCGGCTCACTGCGAGCTCTGCCTCCTGGGTTCAAGCGATTCTCTTGCCTCAGCCTCCTGAGTAGCT
GGGGCTACAGGCGCCTGCCACCACACCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATATTGGCCAGGCTGGTCTTGAA
CTCCTGACCTTGTGATCCGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCTCCTGGCCTATTCTTTTCTTTTC
AGAGACAAGGTCTCACTCTCTCCTCTCGCCCAGGCTGGAGTGCAGTGGTGTCATCATAGCTCATTGCAGCCTCAAACTCCTGGGCTCAAG
CAATCCTCCCACCTCAGCCTCCTGAGTAGCTGGGATCACAGGTGTGTGCTACCTCACCCAGCTAATTTCTAATTTTTTTTTGTAGAGACT
GGATCTCACTGTTGCCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAAGTGCTGGGATTCCAGACCAGCCATTTTTT

>81100_81100_1_SFMBT1-RFT1_SFMBT1_chr3_52977369_ENST00000296295_RFT1_chr3_53133502_ENST00000296292_length(amino acids)=308AA_BP=134
MFWEDIACLYAVEMNGEQQLDADAGSGMEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPETYWVATVITTCE
QLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSS
SFLVLSYLLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGGVTAVSEVFLCCEQGWPARLAHIA

--------------------------------------------------------------
>81100_81100_2_SFMBT1-RFT1_SFMBT1_chr3_52977369_ENST00000296295_RFT1_chr3_53133502_ENST00000394738_length(transcript)=1495nt_BP=733nt
CGCGGAGCGCCGCCGCCGCCTCCGCCGGAGCGCGGGTGGAGGGGGGCGGGGAGAGCTGCCGGCCGCCCCGCTCCGCCGAACCCAGCAGGA
AGGAGGGCGCGAGCGGGCGAGCGCGGGCAGCACGGGAGGAAAAAGCTTCCGCGCGGGGGAGCGAAAAGACGGAAAGAAAGAAAGAAAACG
AGCGCGAGAGGGGGAAAAGCGAGCGATCGAGCGAGCGCGCGCGCGAAAACTCCGGGCAGCACTTTCATTTGGACCCGTGGATACCCATTG
AACAGATGCTTGAAACCTGCAAGTAATCTTCAGATCCTAGCAGAACCATAGGCCTTTCCTTTGTTTTGGGAGGATATAGCCTGCCTATAT
GCTGTGGAAATGAACGGGGAGCAGCAGCTTGATGCAGATGCCGGCTCTGGTATGGAAGAGGTAGAATTAAGCTGGGAAGATTATCTAGAA
GAAACAGGGTCCACAGCAGTTCCCTATGGGTCTTTTAAACATGTGGACACACGTTTGCAAAATGGATTTGCTCCTGGGATGAAGCTGGAG
GTGGCTGTGAGAACAGATCCTGAGACCTACTGGGTTGCCACCGTTATCACTACCTGTGAGCAGTTGCTCCTTCTCCGCTATGATGGCTAT
GGGGAGGATCGGAGAGCAGATTTCTGGTGTGACATCAGGAAGGCTGATCTCTACCCCATTGGGTGGTGTGAGCAGAATAAGAAGACCCTT
GAAGCCCCAGAAGGTCCTGTTTTGCTGCGTTCCTACTGTCTCTATGTTCTCCTGCTTGCCATCAATGGAGTGACAGAGTGTTTCACATTT
GCTGCCATGAGCAAAGAGGAGGTCGACAGGTACAATTTTGTGATGCTGGCCCTGTCCTCCTCATTCCTGGTGTTATCCTATCTCTTGACC
CGTTGGTGTGGCAGCGTGGGCTTCATCTTGGCCAACTGCTTTAACATGGGCATTCGGATCACGCAGAGCCTTTGCTTCATCCACCGCTAC
TACCGAAGGAGCCCCCACAGGCCCCTGGCTGGCCTGCACCTATCGCCAGTCCTGCTCGGGACATTTGCCCTCAGTGGTGGGGTTACTGCT
GTTTCGGAGGTATTCCTCTGCTGTGAGCAGGGCTGGCCAGCCAGACTGGCACACATTGCTGTGGGGGCCTTCTGTCTGGGAGCAACTCTC
GGGACAGCATTCCTCACAGAGACCAAGCTGATCCATTTCCTCAGGACTCAGTTAGGTGTGCCCAGACGCACTGACAAAATGACATGACTT
CAGGGAAGCCTGGACACCCGAGGCACCTGGACCAGCTATGGGTAGTTCTGTGGGTGGAACACATTCTGTGTAAGAGCCCCACTGAGGGCT
CTGCAGCGGAGTGACAGCAACCCCAGAGATGAGGCACCAGAGAGTGCCACTGCATGAGACACCTGTGACCATTCGAAGTCTGAAATGCGG

>81100_81100_2_SFMBT1-RFT1_SFMBT1_chr3_52977369_ENST00000296295_RFT1_chr3_53133502_ENST00000394738_length(amino acids)=308AA_BP=134
MFWEDIACLYAVEMNGEQQLDADAGSGMEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPETYWVATVITTCE
QLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSS
SFLVLSYLLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGGVTAVSEVFLCCEQGWPARLAHIA

--------------------------------------------------------------
>81100_81100_3_SFMBT1-RFT1_SFMBT1_chr3_52977369_ENST00000394752_RFT1_chr3_53133502_ENST00000296292_length(transcript)=4691nt_BP=747nt
GGAATGAGTCGGAGCGCGGAGCGCCGCCGCCGCCTCCGCCGGAGCGCGGGTGGAGGGGGGCGGGGAGAGCTGCCGGCCGCCCCGCTCCGC
CGAACCCAGCAGGAAGGAGGGCGCGAGCGGGCGAGCGCGGGCAGCACGGGAGGAAAAAGCTTCCGCGCGGGGGAGCGAAAAGACGGAAAG
AAAGAAAGAAAACGAGCGCGAGAGGGGGAAAAGCGAGCGATCGAGCGAGCGCGCGCGCGAAAACTCCGGGCAGCACTTTCATTTGGACCC
GTGGATACCCATTGAACAGATGCTTGAAACCTGCAAGTAATCTTCAGATCCTAGCAGAACCATAGGCCTTTCCTTTGTTTTGGGAGGATA
TAGCCTGCCTATATGCTGTGGAAATGAACGGGGAGCAGCAGCTTGATGCAGATGCCGGCTCTGGTATGGAAGAGGTAGAATTAAGCTGGG
AAGATTATCTAGAAGAAACAGGGTCCACAGCAGTTCCCTATGGGTCTTTTAAACATGTGGACACACGTTTGCAAAATGGATTTGCTCCTG
GGATGAAGCTGGAGGTGGCTGTGAGAACAGATCCTGAGACCTACTGGGTTGCCACCGTTATCACTACCTGTGAGCAGTTGCTCCTTCTCC
GCTATGATGGCTATGGGGAGGATCGGAGAGCAGATTTCTGGTGTGACATCAGGAAGGCTGATCTCTACCCCATTGGGTGGTGTGAGCAGA
ATAAGAAGACCCTTGAAGCCCCAGAAGGTCCTGTTTTGCTGCGTTCCTACTGTCTCTATGTTCTCCTGCTTGCCATCAATGGAGTGACAG
AGTGTTTCACATTTGCTGCCATGAGCAAAGAGGAGGTCGACAGGTACAATTTTGTGATGCTGGCCCTGTCCTCCTCATTCCTGGTGTTAT
CCTATCTCTTGACCCGTTGGTGTGGCAGCGTGGGCTTCATCTTGGCCAACTGCTTTAACATGGGCATTCGGATCACGCAGAGCCTTTGCT
TCATCCACCGCTACTACCGAAGGAGCCCCCACAGGCCCCTGGCTGGCCTGCACCTATCGCCAGTCCTGCTCGGGACATTTGCCCTCAGTG
GTGGGGTTACTGCTGTTTCGGAGGTATTCCTCTGCTGTGAGCAGGGCTGGCCAGCCAGACTGGCACACATTGCTGTGGGGGCCTTCTGTC
TGGGAGCAACTCTCGGGACAGCATTCCTCACAGAGACCAAGCTGATCCATTTCCTCAGGACTCAGTTAGGTGTGCCCAGACGCACTGACA
AAATGACATGACTTCAGGGAAGCCTGGACACCCGAGGCACCTGGACCAGCTATGGGTAGTTCTGTGGGTGGAACACATTCTGTGTAAGAG
CCCCACTGAGGGCTCTGCAGCGGAGTGACAGCAACCCCAGAGATGAGGCACCAGAGAGTGCCACTGCATGAGACACCTGTGACCATTCGA
AGTCTGAAATGCGGGGGGGGAGTTTCATTTTTAAGTGAAGACCAAAAGCCCTTTAAAAATAATAGTTTTTTATCATTTTATAGTAATCAG
CATTTTCTCTTTTACTAATATACTCATTCCTTTTGCGTATGATTGGCCTTTGGAGCTACATGCTCCAACAAACTATATCTTAATTGTTAA
CTGTTAATAATTATCTGGCCCAGAAAAAGAGATGCAGTGATTTTACCCTTCACAGGAATATTGAACTTCTTCTGTAAAAGAGAGAGAGAA
ACCTCTCTCTCTCATGCACCACATGGAAACAGAGTGTGGCCCTGAAGTTGTGGCTTTCTTTGTGTCAAAACTGTGGTCTGAGTTTTTAGA
GAAGGAAAAATGCTACTCAGTGAGAAATCCAAGAAATGAAACCAGGAAGGTTTTCAGATCACATTTCCCAGAGTGAGTTCGGGAGAATCT
TGCCTGTCGTGATCACACTGTTCCCCGCCGCCCCAGGTCAGCACATACTTGACCCAGAGTGGGCTCTCAGGATTTGTTGATTGAAGGGTG
GGTGAAAGCTGGCTGGAGACTCCTGGCCTGGCCACCTGCAAGAGGCGGACTTTGAAGAAAACTGTGATCCAGTTGAGCCACTTTGTCCCT
GAGGGGAATGCTGCTTTGCAGCTTTCTGTAACTTCTCACATGGGAATTGCACTGGTGACAGATAAGGTTTAACAGATGTACTTTTTTATC
CTCAGAATAAGACAAGGCAAACTCTATATGGCTAGTATTACTGAGTCAGGTCCCTCCCGTTGACCCATTAATTCCAGCATTGATCAATAC
AACCAAATTCCAGCCCCAGGACAAGAGTGGCAGGCATGGGGGCCTGGTACTCCAGGCTACAGTGTGAGCCCAGGTGTTCTGCACCTTGCA
GCCTGCACACTGCAGGTGAAATCATGAGCAGTGTTCTGGAGTGTGAAGTGTTTTTATTTTTTTGTTAATGTATTAATTCCTTTTAGATAT
TAACCCCCCTCAGAACTATATGCACAAACTATAACTTGGATGTTAATAATCCTGTCACTCAGTGCCCCAAACCTTCTGTGTCTACACCTA
GAGAGAGGGCCAGTAAGGGCAACTCCTATCATGCATTAAAATGCATGTATTTAAATCTGCTTGCCCAGAGCCAGTACCCAGGGGCTAAGG
ATTAAGACCTGTCAGTACACCAAGACTGGGGCCCAGTCACCTGGCAGGTTTTTATCTACTCAGAGGGAGAATGCTTTGCACTAAGTGGGA
GAAAAGCAGCTAAATGCAAGGTGTCCTGAGCAATTAGAGGACCTCCAAAGCATGGCCTCAGTCATGCCTTCATCGGGCAAGGTCAGGCCA
GCTCAGAAAAATGGATGGTCCCATAGGGTCAAGTGGAGCACACACGGAAGGCAGTCCTCCTTCCCTCCCATGTCCTTTCTCTGTCCCTGG
CATCCACAGAAAGGGACCTTCAGTCCTCATGAGCTGCTTCTCTGCAGCTGCTGATCACCCTCCCGGAACCCTGCACCTATCCCGTGCCCA
CCTGACCCCAGACTCAAGCATGATCCTCATTCTACCTGCCTCGGAATCACCTGGATTGCAAGTCAGAACATGGCTTCCCAGGACCCACTC
CAGGCCTTCAGGGTCTGTGTCTCCCAGGAGGAGGGCTCTGAGATTGGCTTTTCTGGCAAGCCCACGTGGCTTTGATGCCACCAAGGTTGG
CATGCCCCATTGTCTTCCTTCGTGACAGGCCCAGGACCATCATGCTCATGCTCACAGTGCCTGTTCTCTGCTCCAGGAACAGAGCTGCTG
CTCTACAAGCAGCCTTGTGACTCCGGGGTCTCTGGGAGCAGGACTCCCCAGGCTTGTGCTCTCTCAGCTTGAGAGAGGCTCTATGTCTGA
AGGCAGTGCTCACTCTCTCATCCCTCCCCTGCTGTTCGCCCAGTGCTGCTGTCAGGGCCAGCTCCTCTTGAAAGACAGCCAGCCGCAAAG
GCAGCCCAGGGCTTCTTCCGGTGTCCTGCTTCCCTGTATCTAGGGAGAGTTGTACATGTGGCTGCGTGTTTTCCCAGGACTAGCCCTGCC
GCCTGGGCTGTCAGCACTTTGGCAGCAGGTCCTCTGTGGTTCTCTGCCTCTGGTGCCTCCCTAAAGCTCAGCTGGACCTGACCAGGCCTC
TGGCATTTCCCCTGCTGGACCCCCTAGAGCCACAGCTGTGCCTCAGGGAGCTTGCATACATGTGGGCCAGCCTGCCTCACTTTACCCAAG
TGGATTTGGGGAGCAGAAATCATACTTTTGGCTTTCAATACCACTTATAGTGAGGCTACTTCTCCATGGAAACAAGTCTCTGAGGCACAA
CCTTTATGAAAGGAAGGAGCATTCGTTGGTGAGAAGAACAGTATCGCTGACTTCCTGTGCTCCTCTGGCCACAGGTAACTGTTGGTCACT
TCAGATTTGGCTTGGGGTCTCTCAGTGAGGAGCTGCTGCTGTGCTGTTTAATGCTTACCTGATGGCAACTTCTGGCTCTGGAACCGCTAC
TCTGCCCTGTTCCCAGCCACTTCCCAACCTGATTCAAGCAGGGCCCCTCCTTCCTCCTGTCTTTATTTATTTATTTATTGAGACAGAGTC
TCACTCTGTCGCCCAGGCTGGAGTGCAGTAGCGCGATCTCGGCTCACTGCGAGCTCTGCCTCCTGGGTTCAAGCGATTCTCTTGCCTCAG
CCTCCTGAGTAGCTGGGGCTACAGGCGCCTGCCACCACACCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATATTGGCC
AGGCTGGTCTTGAACTCCTGACCTTGTGATCCGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCTCCTGGCCT
ATTCTTTTCTTTTCAGAGACAAGGTCTCACTCTCTCCTCTCGCCCAGGCTGGAGTGCAGTGGTGTCATCATAGCTCATTGCAGCCTCAAA
CTCCTGGGCTCAAGCAATCCTCCCACCTCAGCCTCCTGAGTAGCTGGGATCACAGGTGTGTGCTACCTCACCCAGCTAATTTCTAATTTT
TTTTTGTAGAGACTGGATCTCACTGTTGCCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAAGTGCTGGGATTCCAG
ACCAGCCATTTTTTTTCCTTAATCATGCATTCCTGTTGCTAGTTTCACATCAGTCCCCTGGTTTAATAAGAAATAAAATATTTTCTTCAC

>81100_81100_3_SFMBT1-RFT1_SFMBT1_chr3_52977369_ENST00000394752_RFT1_chr3_53133502_ENST00000296292_length(amino acids)=308AA_BP=134
MFWEDIACLYAVEMNGEQQLDADAGSGMEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPETYWVATVITTCE
QLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSS
SFLVLSYLLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGGVTAVSEVFLCCEQGWPARLAHIA

--------------------------------------------------------------
>81100_81100_4_SFMBT1-RFT1_SFMBT1_chr3_52977369_ENST00000394752_RFT1_chr3_53133502_ENST00000394738_length(transcript)=1509nt_BP=747nt
GGAATGAGTCGGAGCGCGGAGCGCCGCCGCCGCCTCCGCCGGAGCGCGGGTGGAGGGGGGCGGGGAGAGCTGCCGGCCGCCCCGCTCCGC
CGAACCCAGCAGGAAGGAGGGCGCGAGCGGGCGAGCGCGGGCAGCACGGGAGGAAAAAGCTTCCGCGCGGGGGAGCGAAAAGACGGAAAG
AAAGAAAGAAAACGAGCGCGAGAGGGGGAAAAGCGAGCGATCGAGCGAGCGCGCGCGCGAAAACTCCGGGCAGCACTTTCATTTGGACCC
GTGGATACCCATTGAACAGATGCTTGAAACCTGCAAGTAATCTTCAGATCCTAGCAGAACCATAGGCCTTTCCTTTGTTTTGGGAGGATA
TAGCCTGCCTATATGCTGTGGAAATGAACGGGGAGCAGCAGCTTGATGCAGATGCCGGCTCTGGTATGGAAGAGGTAGAATTAAGCTGGG
AAGATTATCTAGAAGAAACAGGGTCCACAGCAGTTCCCTATGGGTCTTTTAAACATGTGGACACACGTTTGCAAAATGGATTTGCTCCTG
GGATGAAGCTGGAGGTGGCTGTGAGAACAGATCCTGAGACCTACTGGGTTGCCACCGTTATCACTACCTGTGAGCAGTTGCTCCTTCTCC
GCTATGATGGCTATGGGGAGGATCGGAGAGCAGATTTCTGGTGTGACATCAGGAAGGCTGATCTCTACCCCATTGGGTGGTGTGAGCAGA
ATAAGAAGACCCTTGAAGCCCCAGAAGGTCCTGTTTTGCTGCGTTCCTACTGTCTCTATGTTCTCCTGCTTGCCATCAATGGAGTGACAG
AGTGTTTCACATTTGCTGCCATGAGCAAAGAGGAGGTCGACAGGTACAATTTTGTGATGCTGGCCCTGTCCTCCTCATTCCTGGTGTTAT
CCTATCTCTTGACCCGTTGGTGTGGCAGCGTGGGCTTCATCTTGGCCAACTGCTTTAACATGGGCATTCGGATCACGCAGAGCCTTTGCT
TCATCCACCGCTACTACCGAAGGAGCCCCCACAGGCCCCTGGCTGGCCTGCACCTATCGCCAGTCCTGCTCGGGACATTTGCCCTCAGTG
GTGGGGTTACTGCTGTTTCGGAGGTATTCCTCTGCTGTGAGCAGGGCTGGCCAGCCAGACTGGCACACATTGCTGTGGGGGCCTTCTGTC
TGGGAGCAACTCTCGGGACAGCATTCCTCACAGAGACCAAGCTGATCCATTTCCTCAGGACTCAGTTAGGTGTGCCCAGACGCACTGACA
AAATGACATGACTTCAGGGAAGCCTGGACACCCGAGGCACCTGGACCAGCTATGGGTAGTTCTGTGGGTGGAACACATTCTGTGTAAGAG
CCCCACTGAGGGCTCTGCAGCGGAGTGACAGCAACCCCAGAGATGAGGCACCAGAGAGTGCCACTGCATGAGACACCTGTGACCATTCGA

>81100_81100_4_SFMBT1-RFT1_SFMBT1_chr3_52977369_ENST00000394752_RFT1_chr3_53133502_ENST00000394738_length(amino acids)=308AA_BP=134
MFWEDIACLYAVEMNGEQQLDADAGSGMEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPETYWVATVITTCE
QLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSS
SFLVLSYLLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGGVTAVSEVFLCCEQGWPARLAHIA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SFMBT1-RFT1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SFMBT1-RFT1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SFMBT1-RFT1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource