FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:SFSWAP-MYO1H (FusionGDB2 ID:81154)

Fusion Gene Summary for SFSWAP-MYO1H

check button Fusion gene summary
Fusion gene informationFusion gene name: SFSWAP-MYO1H
Fusion gene ID: 81154
HgeneTgene
Gene symbol

SFSWAP

MYO1H

Gene ID

6433

283446

Gene namesplicing factor SWAPmyosin IH
SynonymsSFRS8|SWAP-
Cytomap

12q24.33

12q24.11

Type of geneprotein-codingprotein-coding
Descriptionsplicing factor, suppressor of white-apricot homologsplicing factor SWAP homologsplicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila)splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot, Drosophila hounconventional myosin-Ihmyosin-1Hmyosin-Ih
Modification date2020031320200313
UniProtAcc.

Q8N1T3

Ensembl transtripts involved in fusion geneENST00000261674, ENST00000541286, 
ENST00000539506, 		ENST00000542883, 
ENST00000310903, ENST00000431443, 
Fusion gene scores* DoF score7 X 7 X 5=2457 X 7 X 4=196
# samples 87
** MAII scorelog2(8/245*10)=-1.61470984411521
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/196*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SFSWAP [Title/Abstract] AND MYO1H [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSFSWAP(132250853)-MYO1H(109845599), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SFSWAP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MYO1H (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-HW-A5KL-01ASFSWAPchr12

132250853

-MYO1Hchr12

109845599

+
ChimerDB4LGGTCGA-HW-A5KL-01ASFSWAPchr12

132250853

+MYO1Hchr12

109845599

+


Top

Fusion Gene ORF analysis for SFSWAP-MYO1H

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000261674ENST00000542883SFSWAPchr12

132250853

+MYO1Hchr12

109845599

+
5CDS-3UTRENST00000541286ENST00000542883SFSWAPchr12

132250853

+MYO1Hchr12

109845599

+
In-frameENST00000261674ENST00000310903SFSWAPchr12

132250853

+MYO1Hchr12

109845599

+
In-frameENST00000261674ENST00000431443SFSWAPchr12

132250853

+MYO1Hchr12

109845599

+
In-frameENST00000541286ENST00000310903SFSWAPchr12

132250853

+MYO1Hchr12

109845599

+
In-frameENST00000541286ENST00000431443SFSWAPchr12

132250853

+MYO1Hchr12

109845599

+
intron-3CDSENST00000539506ENST00000310903SFSWAPchr12

132250853

+MYO1Hchr12

109845599

+
intron-3CDSENST00000539506ENST00000431443SFSWAPchr12

132250853

+MYO1Hchr12

109845599

+
intron-3UTRENST00000539506ENST00000542883SFSWAPchr12

132250853

+MYO1Hchr12

109845599

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000261674SFSWAPchr12132250853+ENST00000310903MYO1Hchr12109845599+5554228312043641414
ENST00000261674SFSWAPchr12132250853+ENST00000431443MYO1Hchr12109845599+5584228312043941424
ENST00000541286SFSWAPchr12132250853+ENST00000310903MYO1Hchr12109845599+550622357243161414
ENST00000541286SFSWAPchr12132250853+ENST00000431443MYO1Hchr12109845599+553622357243461424

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000261674ENST00000310903SFSWAPchr12132250853+MYO1Hchr12109845599+0.001402880.9985971
ENST00000261674ENST00000431443SFSWAPchr12132250853+MYO1Hchr12109845599+0.0008276610.99917233
ENST00000541286ENST00000310903SFSWAPchr12132250853+MYO1Hchr12109845599+0.0013702620.9986298
ENST00000541286ENST00000431443SFSWAPchr12132250853+MYO1Hchr12109845599+0.0008104680.99918956

Top

Fusion Genomic Features for SFSWAP-MYO1H


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SFSWAPchr12132250853+MYO1Hchr12109845598+0.125165220.8748348
SFSWAPchr12132250853+MYO1Hchr12109845598+0.125165220.8748348

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for SFSWAP-MYO1H


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:132250853/chr12:109845599)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MYO1H

Q8N1T3

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318165_168714952.0Compositional biasNote=Poly-Glu
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318287_290714952.0Compositional biasNote=Poly-Asp
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318382_385714952.0Compositional biasNote=Poly-Pro
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318413_416714952.0Compositional biasNote=Poly-Pro
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318420_424714952.0Compositional biasNote=Poly-Pro
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318434_440714952.0Compositional biasNote=Poly-Thr
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318451_454714952.0Compositional biasNote=Poly-Pro
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318616_619714952.0Compositional biasNote=Poly-Ser
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318660_663714952.0Compositional biasNote=Poly-Ala
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319165_1687141004.0Compositional biasNote=Poly-Glu
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319287_2907141004.0Compositional biasNote=Poly-Asp
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319382_3857141004.0Compositional biasNote=Poly-Pro
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319413_4167141004.0Compositional biasNote=Poly-Pro
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319420_4247141004.0Compositional biasNote=Poly-Pro
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319434_4407141004.0Compositional biasNote=Poly-Thr
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319451_4547141004.0Compositional biasNote=Poly-Pro
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319616_6197141004.0Compositional biasNote=Poly-Ser
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319660_6637141004.0Compositional biasNote=Poly-Ala
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318211_253714952.0RepeatNote=SURP motif 1
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318459_499714952.0RepeatNote=SURP motif 2
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319211_2537141004.0RepeatNote=SURP motif 1
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319459_4997141004.0RepeatNote=SURP motif 2
TgeneMYO1Hchr12:132250853chr12:109845599ENST00000431443731704_7263291033.0DomainIQ 1
TgeneMYO1Hchr12:132250853chr12:109845599ENST00000431443731727_7563291033.0DomainIQ 2
TgeneMYO1Hchr12:132250853chr12:109845599ENST00000431443731855_10293291033.0DomainTH1
TgeneMYO1Hchr12:132250853chr12:109845599ENST00000431443731578_6003291033.0RegionActin-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318754_763714952.0Compositional biasNote=Poly-Lys
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318789_951714952.0Compositional biasNote=Arg/Ser-rich (RS domain)
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000261674+1318850_853714952.0Compositional biasNote=Poly-Lys
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319754_7637141004.0Compositional biasNote=Poly-Lys
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319789_9517141004.0Compositional biasNote=Arg/Ser-rich (RS domain)
HgeneSFSWAPchr12:132250853chr12:109845599ENST00000541286+1319850_8537141004.0Compositional biasNote=Poly-Lys
TgeneMYO1Hchr12:132250853chr12:109845599ENST0000043144373112_7013291033.0DomainMyosin motor
TgeneMYO1Hchr12:132250853chr12:109845599ENST00000431443731105_1123291033.0Nucleotide bindingATP


Top

Fusion Gene Sequence for SFSWAP-MYO1H


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>81154_81154_1_SFSWAP-MYO1H_SFSWAP_chr12_132250853_ENST00000261674_MYO1H_chr12_109845599_ENST00000310903_length(transcript)=5554nt_BP=2283nt
CATTTTGTGGCCCGCTATGGCGGCGGTGTTGAGGTTGGGTACGGGATGCGGGGTCTTTGACTGAAGGGGTAGGCCAAGTGGAGGTATCAG
GGACGTCGCGCGGCACAGAAGAGGACCAGCCTGGACGCCGGGGACGCTGTCATGTACGGCGCGAGCGGGGGCCGCGCCAAACCCGAGAGG
AAAAGCGGCGCGAAGGAGGAGGCCGGGCCAGGCGGTGCCGGCGGTGGGGGCAGCCGAGTGGAGCTCTTGGTTTTCGGCTATGCCTGCAAG
CTGTTCCGGGACGACGAGCGGGCCCTGGCTCAGGAACAGGGACAGCACCTCATCCCCTGGATGGGGGACCACAAGATCCTCATCGACAGA
TATGATGGACGTGGTCACCTGCATGACCTTTCTGAGTACGATGCTGAGTATTCCACGTGGAACAGAGATTATCAGCTGTCTGAAGAGGAG
GCGCGAATAGAGGCCCTGTGTGATGAAGAGAGGTATTTAGCCTTGCATACGGACTTGCTTGAGGAGGAGGCAAGGCAAGAGGAAGAATAC
AAGCGATTGAGTGAAGCACTAGCAGAGGATGGGAGCTACAATGCCGTGGGGTTCACTTACGGTAGCGACTATTACGACCCGTCAGAGCCG
ACGGAGGAGGAGGAGCCTTCCAAACAGAGAGAAAAAAATGAGGCCGAAAATTTAGAGGAAAATGAAGAGCCCTTCGTTGCCCCCTTAGGA
TTGAGCGTCCCGTCTGACGTGGAGTTGCCACCAACCGCTAAAATGCACGCCATCATCGAGCGCACGGCCAGCTTCGTGTGCAGGCAGGGA
GCACAGTTTGAGATCATGCTGAAGGCCAAGCAGGCCCGGAACTCCCAGTTTGACTTTCTGCGCTTCGACCACTACCTCAACCCCTACTAT
AAGTTCATCCAGAAAGCCATGAAAGAGGGACGCTACACTGTCCTGGCAGAAAACAAAAGTGACGAGAAAAAAAAATCAGGAGTCAGCTCT
GACAATGAAGATGATGATGATGAAGAAGATGGGAATTACCTTCATCCCTCTCTCTTTGCCTCCAAGAAGTGTAACCGCCTTGAAGAGCTG
ATGAAGCCCTTGAAGGTAGTGGACCCAGATCATCCCCTCGCAGCACTTGTTCGTAAGGCACAGGCTGACAGTTCCACTCCCACCCCACAC
AACGCAGACGGTGCGCCTGTGCAGCCCTCCCAGGTGGAGTACACGGCAGACTCGACCGTGGCAGCCATGTATTACAGCTACTACATGCTA
CCGGACGGCACTTACTGCCTGGCGCCGCCCCCTCCCGGAATCGACGTGACTACTTACTACAGCACCCTTCCTGCTGGCGTGACCGTGTCT
AACTCCCCTGGAGTGACGACCACCGCCCCACCACCTCCTGGGACCACACCACTACCGCCCCCAACCACAGCAGAGACTAGCAGCGGGGCC
ACCTCCACAACCACCACCACAAGTGCACTTGCCCCCGTGGCCGCCATCATCCCCCCGCCCCCCGACGTCCAGCCCGTGATTGACAAGCTG
GCCGAGTATGTCGCCAGGAACGGCCTGAAGTTCGAGACCAGTGTTCGTGCCAAGAATGATCAAAGATTTGAGTTCCTGCAGCCGTGGCAC
CAGTATAATGCTTATTATGAGTTTAAGAAGCAGTTCTTCCTCCAGAAAGAAGGGGGCGATAGCATGCAGGCTGTGTCTGCACCAGAAGAG
GCTCCCACAGACTCTGCTCCCGAGAAGCCAAGTGATGCTGGGGAGGATGGCGCGCCTGAAGACGCAGCCGAGGTGGGAGCACGGGCAGGC
TCAGGCGGGAAGAAGGAGGCATCGTCCAGTAAGACCGTCCCGGACGGGAAGCTGGTGAAAGCTTCCTTTGCTCCAATAAGCTTTGCAATC
AAGGCCAAAGAAAATGATCTGCTTCCCCTGGAAAAAAATCGTGTTAAGCTAGATGATGACAGTGATGATGATGAAGAAAGCAAAGAAGGC
CAAGAAAGTTCTAGTAGTGCTGCAAACACTAACCCAGCAGTTGCCCCACCCTGTGTAGTTGTTGAGGAGAAGAAGCCTCAACTTACCCAG
GAGGAGCTAGAAGCAAAGCAAGCAAAGCAAAAGCTGGAAGATCGCCTCGCAGCTGCTGCCCGGGAAAAGCTGGCCCAGGCGTCTAAGGAG
TCAAAAGAGAAACAGCTTCAAGCAGAACGTAAAAGGAAAGCGGCGTTATTTTTACAGACCCTCAAAAATCCTCTGCCGGAAGCAGAAGCT
GGGAAAATTGAGGAGAGTCCTTTCAGTGTCGAGGTGATCTGCCCGTTGACACTAGAACTCTCTGTCTACGCTAGAGATGCAATGGCAAAG
GCTGTTTATGGACGAACGTTTACTTGGCTGGTCAACAAAATCAATTCCTCCTTAGTTAACAAGGATTTCACCAGGAAAACTGTAATTGGA
TTACTGGACATCTATGGGTTTGAAGTCTTTGACAAGAATGGTTTTGAACAGTTCTGTATAAATTACTGCAATGAGAAACTCCAGCAACTG
TTAATTGAGAGGACTCTAAAAGCAGAACAGGCAGAATATGAAATGGAAGGCATAGAGTGGGAGCCAATTAAATATTTCAACAACAAGATC
ATCTGTGATTTGGTAGAAGAGAGACATAAAGGAATCATATCTATTCTGGATGAAGAATGCATTCGGCCTGGTCCTGCTACAGACTTGAGT
TTCCTGGAGAAATTGGAAGAGAAAGTGGGCAAACATGCACACTTCGAAACCCGTAAGCTGGCTGGTCCAAAGGGCCGAAAGAGGATTGGC
TGGATGGAGTTCCGACTCCTCCACTATGCAGGAGAGGTCACATACTGCACCAAGGGATTCTTGGAAAAAAACAATGATCTTCTTTACAGA
CATCTGAAAGAAGTGCTGTGCAAGTCCAAGAACATTATCCTGAGGGAATGCTTCCTGCTGGCCGAGTTAGAAAACCGGAGGAGGCCCCCA
ACAGTGGGGACTCAGTTTAAAAACAGTCTGAGCAGCCTTCTAGAAACCCTCATCTCTAAGGAGCCCTCCTACATCCGTTGCATCAAGCCC
AACGACAGGAAAGAACCCAGCAAATTTGATGACTTCCTCATAAGGCATCAGATCAAATACCTGGGGCTGATGGAGCACCTGCGGGTGAGA
CGGGCTGGTTTTGCATACCGAAGGAAATACGAGCATTTCTTGCAAAGGTACAAGTCCTTATGCCCAGACACCTGGCCGCACTGGCACGGG
CCTCCAGCAGAGGGCGTGGAACGGCTGATCAAGTACATCGGCTACAAACCCGAGGAATACAAGTTAGGCAAAACCAAAATATTCATTCGT
TTCCCCAGAACTCTGTTTGCTACCGAAGATGCCTTTGAATTTAGTAAACATCAACTAGTTGCAAGAATCCAAGCCACTTACAAACGCTGC
CTAGGAAGGAGAGAATACGTGAAAAAAAGACAAGCAGCCATCAAACTGGAAGCCCACTGGCGTGGGGCCCTGGCTCGGAAGGCAATCCAA
AGGAGAAAGTGGGCCGTGCGGATTATCAGAAAGTTCATTAAAGGATTCATCAGTCGCAACAAACCCCTCTGTCCTGACAACGAGGAATTT
ATCGTGTTTGTGCGGAAGAATTACATCTTGAATCTCCGGTATCACCTTCCAAAGACTGTCCTGGACAAGAGCTGGCTGAGGCCTCCTGGC
ATCTTGGAAAATGCATCAGATCTGCTCAGGAAAATGTGCGTGAGGAACCTGGTGCAGAAGTACTGCCGCGGGATCACAGCTGAGCGGAAA
GCAATGATGCAGCAAAAGGTAGTTACAAGTGAAATCTTCAGGGGAAGGAAAGACGGCTACACAGAAAGTTTAAATCAACCCTTTGTCAAC
AGTCGGATAGATGAAGGAGACATTAATCCGAAAGTGCTTCAGCTAATTAGCCATGAGAAAATCCAGTATGGTGTCCCGGTCATTAAATAT
GACAGAAAAGGCTTCAAAGCACGGCAGCGGCAACTCATTCTTACTCAGAAAGCAGCTTACGTGGTGGAACTTGCCAAAATCAAGCAGAAA
ATAGAGTACTCAGCTCTCAAAGGTGTCTCCACTAGCAATCTGAGTGATGGAATCTTAGTCATTCATGTTTCACCAGAGGACAGCAAGCAA
AAGGGGGATGCCGTTTTGCAGTGTGGACACGTGTTTGAAGCAGTTACTAAACTCGTCATGCTGGTTAAGAAGGAGAACATTGTCAATGTT
GTTCAAGGAAGTTTACAGTTTTTTATTAGTCCGGGAAAAGAAGGCACAATAGTTTTCGACACTGGACTGGAAGAACAAGTCTATAAAAAT
AAAAATGGACAATTAACAGTGGTGTCAGTCCGGAGGAAGTCCTGATAGAGGATGACGTCTGACCTCTACCATCGCCATTTTTGCTCCAAC
TGAGGAAACTACAGGGGAAGTGGGGATTGGATCCAGTTAGCTACCTCTTCAAGGTACCAGGCCCGCAGCACTAACAGATCACATCTGAAG
AAACTGAGGGGCGTTAGGCCAAAGCCTAATCCCAGCTCCTCAGCTGCCCCATGGCACCTTATTTAAAATGTCACCTTCTGGAAGCAGACC
CCAGGTCACCCGAAGGCGCAATTCTAAACACCCTCGACAGGATCTATGTTCAGTGCGCAGTCCAACGTGTCATTAGAGGGTGGGCAAGAT
TCTCTACCTCTGTCAAGCTGCCCTGAGACATGATGAAATACTGTGTACAGCAAGTTCTCAAATAACATTTCGTTATATGTTGATAAGACA
TCTGATTCCTGGGCAGGGCCACTGTCTGGGTGGAGTCTGTATGTTCTCCCCATGTCTCTGGGTTTCTTCTGGGTGCTCTGGTTTCCTCCC
ACGTCCCCAAGGTGTGTGTGTCAGGTGCACTGGCGTGTCTATGCGGTCCCAGTCTGAGTGAGTGTGGGTGCGTGAGCCCCGTGAGAGGAG
GACATCCTGTCCAGGGTGGGTCCCGCCTTCTGCCCTGAGCTGCTGGGATTGGGCTCTGGCCATCTGCAACCCTGAACGTGCAGGTTGGAG
AACGAATGAATACAAATTTTATTGTAAAATAAAAATGTATATAAAGCATATGAGCACACAAATGGACAATAAATGCCACAGCGCAAAAGC
GTGTAGCGAGCCTGCCACGCTTGTGACTGGGGAGGGGCTCCGTATAATCTCACCTTTGCAAGCGTTTATTTACTGATGTATGCGGCCACC
ACTGTGACCACCATCACTTACCGATTCACCAAAACTTAGGTAATATGGTCTTATTTTTGATTTAATTAAATATACGTGTAGCTCATGTAT
TTCACAGTTTAATATGAGAAGTGCTTTGGTCTTTATTTAGAAATTGGGTGATGTTTTTGTGCCCAGCAACATGCTGTAGGAATTTAACTC
TTGTTTACATCCATTAGCCTCATGGTTTTGCTTCAAGTCTCAGCTTCCAAGAACCTATCGATGACTTACTGTGCATGGTCTGAGACTAAG

>81154_81154_1_SFSWAP-MYO1H_SFSWAP_chr12_132250853_ENST00000261674_MYO1H_chr12_109845599_ENST00000310903_length(amino acids)=1414AA_BP=721
MDAGDAVMYGASGGRAKPERKSGAKEEAGPGGAGGGGSRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDL
SEYDAEYSTWNRDYQLSEEEARIEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQR
EKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEG
RYTVLAENKSDEKKKSGVSSDNEDDDDEEDGNYLHPSLFASKKCNRLEELMKPLKVVDPDHPLAALVRKAQADSSTPTPHNADGAPVQPS
QVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSAL
APVAAIIPPPPDVQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKP
SDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANT
NPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSV
EVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQ
AEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYA
GEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFD
DFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATED
AFEFSKHQLVARIQATYKRCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKNYIL
NLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDINP
KVLQLISHEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQKGDAVLQCGH

--------------------------------------------------------------
>81154_81154_2_SFSWAP-MYO1H_SFSWAP_chr12_132250853_ENST00000261674_MYO1H_chr12_109845599_ENST00000431443_length(transcript)=5584nt_BP=2283nt
CATTTTGTGGCCCGCTATGGCGGCGGTGTTGAGGTTGGGTACGGGATGCGGGGTCTTTGACTGAAGGGGTAGGCCAAGTGGAGGTATCAG
GGACGTCGCGCGGCACAGAAGAGGACCAGCCTGGACGCCGGGGACGCTGTCATGTACGGCGCGAGCGGGGGCCGCGCCAAACCCGAGAGG
AAAAGCGGCGCGAAGGAGGAGGCCGGGCCAGGCGGTGCCGGCGGTGGGGGCAGCCGAGTGGAGCTCTTGGTTTTCGGCTATGCCTGCAAG
CTGTTCCGGGACGACGAGCGGGCCCTGGCTCAGGAACAGGGACAGCACCTCATCCCCTGGATGGGGGACCACAAGATCCTCATCGACAGA
TATGATGGACGTGGTCACCTGCATGACCTTTCTGAGTACGATGCTGAGTATTCCACGTGGAACAGAGATTATCAGCTGTCTGAAGAGGAG
GCGCGAATAGAGGCCCTGTGTGATGAAGAGAGGTATTTAGCCTTGCATACGGACTTGCTTGAGGAGGAGGCAAGGCAAGAGGAAGAATAC
AAGCGATTGAGTGAAGCACTAGCAGAGGATGGGAGCTACAATGCCGTGGGGTTCACTTACGGTAGCGACTATTACGACCCGTCAGAGCCG
ACGGAGGAGGAGGAGCCTTCCAAACAGAGAGAAAAAAATGAGGCCGAAAATTTAGAGGAAAATGAAGAGCCCTTCGTTGCCCCCTTAGGA
TTGAGCGTCCCGTCTGACGTGGAGTTGCCACCAACCGCTAAAATGCACGCCATCATCGAGCGCACGGCCAGCTTCGTGTGCAGGCAGGGA
GCACAGTTTGAGATCATGCTGAAGGCCAAGCAGGCCCGGAACTCCCAGTTTGACTTTCTGCGCTTCGACCACTACCTCAACCCCTACTAT
AAGTTCATCCAGAAAGCCATGAAAGAGGGACGCTACACTGTCCTGGCAGAAAACAAAAGTGACGAGAAAAAAAAATCAGGAGTCAGCTCT
GACAATGAAGATGATGATGATGAAGAAGATGGGAATTACCTTCATCCCTCTCTCTTTGCCTCCAAGAAGTGTAACCGCCTTGAAGAGCTG
ATGAAGCCCTTGAAGGTAGTGGACCCAGATCATCCCCTCGCAGCACTTGTTCGTAAGGCACAGGCTGACAGTTCCACTCCCACCCCACAC
AACGCAGACGGTGCGCCTGTGCAGCCCTCCCAGGTGGAGTACACGGCAGACTCGACCGTGGCAGCCATGTATTACAGCTACTACATGCTA
CCGGACGGCACTTACTGCCTGGCGCCGCCCCCTCCCGGAATCGACGTGACTACTTACTACAGCACCCTTCCTGCTGGCGTGACCGTGTCT
AACTCCCCTGGAGTGACGACCACCGCCCCACCACCTCCTGGGACCACACCACTACCGCCCCCAACCACAGCAGAGACTAGCAGCGGGGCC
ACCTCCACAACCACCACCACAAGTGCACTTGCCCCCGTGGCCGCCATCATCCCCCCGCCCCCCGACGTCCAGCCCGTGATTGACAAGCTG
GCCGAGTATGTCGCCAGGAACGGCCTGAAGTTCGAGACCAGTGTTCGTGCCAAGAATGATCAAAGATTTGAGTTCCTGCAGCCGTGGCAC
CAGTATAATGCTTATTATGAGTTTAAGAAGCAGTTCTTCCTCCAGAAAGAAGGGGGCGATAGCATGCAGGCTGTGTCTGCACCAGAAGAG
GCTCCCACAGACTCTGCTCCCGAGAAGCCAAGTGATGCTGGGGAGGATGGCGCGCCTGAAGACGCAGCCGAGGTGGGAGCACGGGCAGGC
TCAGGCGGGAAGAAGGAGGCATCGTCCAGTAAGACCGTCCCGGACGGGAAGCTGGTGAAAGCTTCCTTTGCTCCAATAAGCTTTGCAATC
AAGGCCAAAGAAAATGATCTGCTTCCCCTGGAAAAAAATCGTGTTAAGCTAGATGATGACAGTGATGATGATGAAGAAAGCAAAGAAGGC
CAAGAAAGTTCTAGTAGTGCTGCAAACACTAACCCAGCAGTTGCCCCACCCTGTGTAGTTGTTGAGGAGAAGAAGCCTCAACTTACCCAG
GAGGAGCTAGAAGCAAAGCAAGCAAAGCAAAAGCTGGAAGATCGCCTCGCAGCTGCTGCCCGGGAAAAGCTGGCCCAGGCGTCTAAGGAG
TCAAAAGAGAAACAGCTTCAAGCAGAACGTAAAAGGAAAGCGGCGTTATTTTTACAGACCCTCAAAAATCCTCTGCCGGAAGCAGAAGCT
GGGAAAATTGAGGAGAGTCCTTTCAGTGTCGAGGTGATCTGCCCGTTGACACTAGAACTCTCTGTCTACGCTAGAGATGCAATGGCAAAG
GCTGTTTATGGACGAACGTTTACTTGGCTGGTCAACAAAATCAATTCCTCCTTAGTTAACAAGGTTGGTCAACGCATTTTGGATCCCTTG
CTCTTGCTCACGTGGAAAACTGTAATTGGATTACTGGACATCTATGGGTTTGAAGTCTTTGACAAGAATGGTTTTGAACAGTTCTGTATA
AATTACTGCAATGAGAAACTCCAGCAACTGTTAATTGAGAGGACTCTAAAAGCAGAACAGGCAGAATATGAAATGGAAGGCATAGAGTGG
GAGCCAATTAAATATTTCAACAACAAGATCATCTGTGATTTGGTAGAAGAGAGACATAAAGGAATCATATCTATTCTGGATGAAGAATGC
ATTCGGCCTGGTCCTGCTACAGACTTGAGTTTCCTGGAGAAATTGGAAGAGAAAGTGGGCAAACATGCACACTTCGAAACCCGTAAGCTG
GCTGGTCCAAAGGGCCGAAAGAGGATTGGCTGGATGGAGTTCCGACTCCTCCACTATGCAGGAGAGGTCACATACTGCACCAAGGGATTC
TTGGAAAAAAACAATGATCTTCTTTACAGACATCTGAAAGAAGTGCTGTGCAAGTCCAAGAACATTATCCTGAGGGAATGCTTCCTGCTG
GCCGAGTTAGAAAACCGGAGGAGGCCCCCAACAGTGGGGACTCAGTTTAAAAACAGTCTGAGCAGCCTTCTAGAAACCCTCATCTCTAAG
GAGCCCTCCTACATCCGTTGCATCAAGCCCAACGACAGGAAAGAACCCAGCAAATTTGATGACTTCCTCATAAGGCATCAGATCAAATAC
CTGGGGCTGATGGAGCACCTGCGGGTGAGACGGGCTGGTTTTGCATACCGAAGGAAATACGAGCATTTCTTGCAAAGGTACAAGTCCTTA
TGCCCAGACACCTGGCCGCACTGGCACGGGCCTCCAGCAGAGGGCGTGGAACGGCTGATCAAGTACATCGGCTACAAACCCGAGGAATAC
AAGTTAGGCAAAACCAAAATATTCATTCGTTTCCCCAGAACTCTGTTTGCTACCGAAGATGCCTTTGAATTTAGTAAACATCAACTAGTT
GCAAGAATCCAAGCCACTTACAAACGCTGCCTAGGAAGGAGAGAATACGTGAAAAAAAGACAAGCAGCCATCAAACTGGAAGCCCACTGG
CGTGGGGCCCTGGCTCGGAAGGCAATCCAAAGGAGAAAGTGGGCCGTGCGGATTATCAGAAAGTTCATTAAAGGATTCATCAGTCGCAAC
AAACCCCTCTGTCCTGACAACGAGGAATTTATCGTGTTTGTGCGGAAGAATTACATCTTGAATCTCCGGTATCACCTTCCAAAGACTGTC
CTGGACAAGAGCTGGCTGAGGCCTCCTGGCATCTTGGAAAATGCATCAGATCTGCTCAGGAAAATGTGCGTGAGGAACCTGGTGCAGAAG
TACTGCCGCGGGATCACAGCTGAGCGGAAAGCAATGATGCAGCAAAAGGTAGTTACAAGTGAAATCTTCAGGGGAAGGAAAGACGGCTAC
ACAGAAAGTTTAAATCAACCCTTTGTCAACAGTCGGATAGATGAAGGAGACATTAATCCGAAAGTGCTTCAGCTAATTAGCCATGAGAAA
ATCCAGTATGGTGTCCCGGTCATTAAATATGACAGAAAAGGCTTCAAAGCACGGCAGCGGCAACTCATTCTTACTCAGAAAGCAGCTTAC
GTGGTGGAACTTGCCAAAATCAAGCAGAAAATAGAGTACTCAGCTCTCAAAGGTGTCTCCACTAGCAATCTGAGTGATGGAATCTTAGTC
ATTCATGTTTCACCAGAGGACAGCAAGCAAAAGGGGGATGCCGTTTTGCAGTGTGGACACGTGTTTGAAGCAGTTACTAAACTCGTCATG
CTGGTTAAGAAGGAGAACATTGTCAATGTTGTTCAAGGAAGTTTACAGTTTTTTATTAGTCCGGGAAAAGAAGGCACAATAGTTTTCGAC
ACTGGACTGGAAGAACAAGTCTATAAAAATAAAAATGGACAATTAACAGTGGTGTCAGTCCGGAGGAAGTCCTGATAGAGGATGACGTCT
GACCTCTACCATCGCCATTTTTGCTCCAACTGAGGAAACTACAGGGGAAGTGGGGATTGGATCCAGTTAGCTACCTCTTCAAGGTACCAG
GCCCGCAGCACTAACAGATCACATCTGAAGAAACTGAGGGGCGTTAGGCCAAAGCCTAATCCCAGCTCCTCAGCTGCCCCATGGCACCTT
ATTTAAAATGTCACCTTCTGGAAGCAGACCCCAGGTCACCCGAAGGCGCAATTCTAAACACCCTCGACAGGATCTATGTTCAGTGCGCAG
TCCAACGTGTCATTAGAGGGTGGGCAAGATTCTCTACCTCTGTCAAGCTGCCCTGAGACATGATGAAATACTGTGTACAGCAAGTTCTCA
AATAACATTTCGTTATATGTTGATAAGACATCTGATTCCTGGGCAGGGCCACTGTCTGGGTGGAGTCTGTATGTTCTCCCCATGTCTCTG
GGTTTCTTCTGGGTGCTCTGGTTTCCTCCCACGTCCCCAAGGTGTGTGTGTCAGGTGCACTGGCGTGTCTATGCGGTCCCAGTCTGAGTG
AGTGTGGGTGCGTGAGCCCCGTGAGAGGAGGACATCCTGTCCAGGGTGGGTCCCGCCTTCTGCCCTGAGCTGCTGGGATTGGGCTCTGGC
CATCTGCAACCCTGAACGTGCAGGTTGGAGAACGAATGAATACAAATTTTATTGTAAAATAAAAATGTATATAAAGCATATGAGCACACA
AATGGACAATAAATGCCACAGCGCAAAAGCGTGTAGCGAGCCTGCCACGCTTGTGACTGGGGAGGGGCTCCGTATAATCTCACCTTTGCA
AGCGTTTATTTACTGATGTATGCGGCCACCACTGTGACCACCATCACTTACCGATTCACCAAAACTTAGGTAATATGGTCTTATTTTTGA
TTTAATTAAATATACGTGTAGCTCATGTATTTCACAGTTTAATATGAGAAGTGCTTTGGTCTTTATTTAGAAATTGGGTGATGTTTTTGT
GCCCAGCAACATGCTGTAGGAATTTAACTCTTGTTTACATCCATTAGCCTCATGGTTTTGCTTCAAGTCTCAGCTTCCAAGAACCTATCG
ATGACTTACTGTGCATGGTCTGAGACTAAGTAAAGGAAATTTCCTAAAGCTGTGAAATTTGAATTTTGCTTTAAATAAATGGAACTCACA

>81154_81154_2_SFSWAP-MYO1H_SFSWAP_chr12_132250853_ENST00000261674_MYO1H_chr12_109845599_ENST00000431443_length(amino acids)=1424AA_BP=721
MDAGDAVMYGASGGRAKPERKSGAKEEAGPGGAGGGGSRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDL
SEYDAEYSTWNRDYQLSEEEARIEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQR
EKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEG
RYTVLAENKSDEKKKSGVSSDNEDDDDEEDGNYLHPSLFASKKCNRLEELMKPLKVVDPDHPLAALVRKAQADSSTPTPHNADGAPVQPS
QVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSAL
APVAAIIPPPPDVQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKP
SDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANT
NPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSV
EVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKVGQRILDPLLLLTWKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQL
LIERTLKAEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRKLAGPKGRKRIG
WMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKP
NDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIR
FPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEF
IVFVRKNYILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVN
SRIDEGDINPKVLQLISHEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQ

--------------------------------------------------------------
>81154_81154_3_SFSWAP-MYO1H_SFSWAP_chr12_132250853_ENST00000541286_MYO1H_chr12_109845599_ENST00000310903_length(transcript)=5506nt_BP=2235nt
CGGGGTCTTTGACTGAAGGGGTAGGCCAAGTGGAGGTATCAGGGACGTCGCGCGGCACAGAAGAGGACCAGCCTGGACGCCGGGGACGCT
GTCATGTACGGCGCGAGCGGGGGCCGCGCCAAACCCGAGAGGAAAAGCGGCGCGAAGGAGGAGGCCGGGCCAGGCGGTGCCGGCGGTGGG
GGCAGCCGAGTGGAGCTCTTGGTTTTCGGCTATGCCTGCAAGCTGTTCCGGGACGACGAGCGGGCCCTGGCTCAGGAACAGGGACAGCAC
CTCATCCCCTGGATGGGGGACCACAAGATCCTCATCGACAGATATGATGGACGTGGTCACCTGCATGACCTTTCTGAGTACGATGCTGAG
TATTCCACGTGGAACAGAGATTATCAGCTGTCTGAAGAGGAGGCGCGAATAGAGGCCCTGTGTGATGAAGAGAGGTATTTAGCCTTGCAT
ACGGACTTGCTTGAGGAGGAGGCAAGGCAAGAGGAAGAATACAAGCGATTGAGTGAAGCACTAGCAGAGGATGGGAGCTACAATGCCGTG
GGGTTCACTTACGGTAGCGACTATTACGACCCGTCAGAGCCGACGGAGGAGGAGGAGCCTTCCAAACAGAGAGAAAAAAATGAGGCCGAA
AATTTAGAGGAAAATGAAGAGCCCTTCGTTGCCCCCTTAGGATTGAGCGTCCCGTCTGACGTGGAGTTGCCACCAACCGCTAAAATGCAC
GCCATCATCGAGCGCACGGCCAGCTTCGTGTGCAGGCAGGGAGCACAGTTTGAGATCATGCTGAAGGCCAAGCAGGCCCGGAACTCCCAG
TTTGACTTTCTGCGCTTCGACCACTACCTCAACCCCTACTATAAGTTCATCCAGAAAGCCATGAAAGAGGGACGCTACACTGTCCTGGCA
GAAAACAAAAGTGACGAGAAAAAAAAATCAGGAGTCAGCTCTGACAATGAAGATGATGATGATGAAGAAGATGGGAATTACCTTCATCCC
TCTCTCTTTGCCTCCAAGAAGTGTAACCGCCTTGAAGAGCTGATGAAGCCCTTGAAGGTAGTGGACCCAGATCATCCCCTCGCAGCACTT
GTTCGTAAGGCACAGGCTGACAGTTCCACTCCCACCCCACACAACGCAGACGGTGCGCCTGTGCAGCCCTCCCAGGTGGAGTACACGGCA
GACTCGACCGTGGCAGCCATGTATTACAGCTACTACATGCTACCGGACGGCACTTACTGCCTGGCGCCGCCCCCTCCCGGAATCGACGTG
ACTACTTACTACAGCACCCTTCCTGCTGGCGTGACCGTGTCTAACTCCCCTGGAGTGACGACCACCGCCCCACCACCTCCTGGGACCACA
CCACTACCGCCCCCAACCACAGCAGAGACTAGCAGCGGGGCCACCTCCACAACCACCACCACAAGTGCACTTGCCCCCGTGGCCGCCATC
ATCCCCCCGCCCCCCGACGTCCAGCCCGTGATTGACAAGCTGGCCGAGTATGTCGCCAGGAACGGCCTGAAGTTCGAGACCAGTGTTCGT
GCCAAGAATGATCAAAGATTTGAGTTCCTGCAGCCGTGGCACCAGTATAATGCTTATTATGAGTTTAAGAAGCAGTTCTTCCTCCAGAAA
GAAGGGGGCGATAGCATGCAGGCTGTGTCTGCACCAGAAGAGGCTCCCACAGACTCTGCTCCCGAGAAGCCAAGTGATGCTGGGGAGGAT
GGCGCGCCTGAAGACGCAGCCGAGGTGGGAGCACGGGCAGGCTCAGGCGGGAAGAAGGAGGCATCGTCCAGTAAGACCGTCCCGGACGGG
AAGCTGGTGAAAGCTTCCTTTGCTCCAATAAGCTTTGCAATCAAGGCCAAAGAAAATGATCTGCTTCCCCTGGAAAAAAATCGTGTTAAG
CTAGATGATGACAGTGATGATGATGAAGAAAGCAAAGAAGGCCAAGAAAGTTCTAGTAGTGCTGCAAACACTAACCCAGCAGTTGCCCCA
CCCTGTGTAGTTGTTGAGGAGAAGAAGCCTCAACTTACCCAGGAGGAGCTAGAAGCAAAGCAAGCAAAGCAAAAGCTGGAAGATCGCCTC
GCAGCTGCTGCCCGGGAAAAGCTGGCCCAGGCGTCTAAGGAGTCAAAAGAGAAACAGCTTCAAGCAGAACGTAAAAGGAAAGCGGCGTTA
TTTTTACAGACCCTCAAAAATCCTCTGCCGGAAGCAGAAGCTGGGAAAATTGAGGAGAGTCCTTTCAGTGTCGAGGTGATCTGCCCGTTG
ACACTAGAACTCTCTGTCTACGCTAGAGATGCAATGGCAAAGGCTGTTTATGGACGAACGTTTACTTGGCTGGTCAACAAAATCAATTCC
TCCTTAGTTAACAAGGATTTCACCAGGAAAACTGTAATTGGATTACTGGACATCTATGGGTTTGAAGTCTTTGACAAGAATGGTTTTGAA
CAGTTCTGTATAAATTACTGCAATGAGAAACTCCAGCAACTGTTAATTGAGAGGACTCTAAAAGCAGAACAGGCAGAATATGAAATGGAA
GGCATAGAGTGGGAGCCAATTAAATATTTCAACAACAAGATCATCTGTGATTTGGTAGAAGAGAGACATAAAGGAATCATATCTATTCTG
GATGAAGAATGCATTCGGCCTGGTCCTGCTACAGACTTGAGTTTCCTGGAGAAATTGGAAGAGAAAGTGGGCAAACATGCACACTTCGAA
ACCCGTAAGCTGGCTGGTCCAAAGGGCCGAAAGAGGATTGGCTGGATGGAGTTCCGACTCCTCCACTATGCAGGAGAGGTCACATACTGC
ACCAAGGGATTCTTGGAAAAAAACAATGATCTTCTTTACAGACATCTGAAAGAAGTGCTGTGCAAGTCCAAGAACATTATCCTGAGGGAA
TGCTTCCTGCTGGCCGAGTTAGAAAACCGGAGGAGGCCCCCAACAGTGGGGACTCAGTTTAAAAACAGTCTGAGCAGCCTTCTAGAAACC
CTCATCTCTAAGGAGCCCTCCTACATCCGTTGCATCAAGCCCAACGACAGGAAAGAACCCAGCAAATTTGATGACTTCCTCATAAGGCAT
CAGATCAAATACCTGGGGCTGATGGAGCACCTGCGGGTGAGACGGGCTGGTTTTGCATACCGAAGGAAATACGAGCATTTCTTGCAAAGG
TACAAGTCCTTATGCCCAGACACCTGGCCGCACTGGCACGGGCCTCCAGCAGAGGGCGTGGAACGGCTGATCAAGTACATCGGCTACAAA
CCCGAGGAATACAAGTTAGGCAAAACCAAAATATTCATTCGTTTCCCCAGAACTCTGTTTGCTACCGAAGATGCCTTTGAATTTAGTAAA
CATCAACTAGTTGCAAGAATCCAAGCCACTTACAAACGCTGCCTAGGAAGGAGAGAATACGTGAAAAAAAGACAAGCAGCCATCAAACTG
GAAGCCCACTGGCGTGGGGCCCTGGCTCGGAAGGCAATCCAAAGGAGAAAGTGGGCCGTGCGGATTATCAGAAAGTTCATTAAAGGATTC
ATCAGTCGCAACAAACCCCTCTGTCCTGACAACGAGGAATTTATCGTGTTTGTGCGGAAGAATTACATCTTGAATCTCCGGTATCACCTT
CCAAAGACTGTCCTGGACAAGAGCTGGCTGAGGCCTCCTGGCATCTTGGAAAATGCATCAGATCTGCTCAGGAAAATGTGCGTGAGGAAC
CTGGTGCAGAAGTACTGCCGCGGGATCACAGCTGAGCGGAAAGCAATGATGCAGCAAAAGGTAGTTACAAGTGAAATCTTCAGGGGAAGG
AAAGACGGCTACACAGAAAGTTTAAATCAACCCTTTGTCAACAGTCGGATAGATGAAGGAGACATTAATCCGAAAGTGCTTCAGCTAATT
AGCCATGAGAAAATCCAGTATGGTGTCCCGGTCATTAAATATGACAGAAAAGGCTTCAAAGCACGGCAGCGGCAACTCATTCTTACTCAG
AAAGCAGCTTACGTGGTGGAACTTGCCAAAATCAAGCAGAAAATAGAGTACTCAGCTCTCAAAGGTGTCTCCACTAGCAATCTGAGTGAT
GGAATCTTAGTCATTCATGTTTCACCAGAGGACAGCAAGCAAAAGGGGGATGCCGTTTTGCAGTGTGGACACGTGTTTGAAGCAGTTACT
AAACTCGTCATGCTGGTTAAGAAGGAGAACATTGTCAATGTTGTTCAAGGAAGTTTACAGTTTTTTATTAGTCCGGGAAAAGAAGGCACA
ATAGTTTTCGACACTGGACTGGAAGAACAAGTCTATAAAAATAAAAATGGACAATTAACAGTGGTGTCAGTCCGGAGGAAGTCCTGATAG
AGGATGACGTCTGACCTCTACCATCGCCATTTTTGCTCCAACTGAGGAAACTACAGGGGAAGTGGGGATTGGATCCAGTTAGCTACCTCT
TCAAGGTACCAGGCCCGCAGCACTAACAGATCACATCTGAAGAAACTGAGGGGCGTTAGGCCAAAGCCTAATCCCAGCTCCTCAGCTGCC
CCATGGCACCTTATTTAAAATGTCACCTTCTGGAAGCAGACCCCAGGTCACCCGAAGGCGCAATTCTAAACACCCTCGACAGGATCTATG
TTCAGTGCGCAGTCCAACGTGTCATTAGAGGGTGGGCAAGATTCTCTACCTCTGTCAAGCTGCCCTGAGACATGATGAAATACTGTGTAC
AGCAAGTTCTCAAATAACATTTCGTTATATGTTGATAAGACATCTGATTCCTGGGCAGGGCCACTGTCTGGGTGGAGTCTGTATGTTCTC
CCCATGTCTCTGGGTTTCTTCTGGGTGCTCTGGTTTCCTCCCACGTCCCCAAGGTGTGTGTGTCAGGTGCACTGGCGTGTCTATGCGGTC
CCAGTCTGAGTGAGTGTGGGTGCGTGAGCCCCGTGAGAGGAGGACATCCTGTCCAGGGTGGGTCCCGCCTTCTGCCCTGAGCTGCTGGGA
TTGGGCTCTGGCCATCTGCAACCCTGAACGTGCAGGTTGGAGAACGAATGAATACAAATTTTATTGTAAAATAAAAATGTATATAAAGCA
TATGAGCACACAAATGGACAATAAATGCCACAGCGCAAAAGCGTGTAGCGAGCCTGCCACGCTTGTGACTGGGGAGGGGCTCCGTATAAT
CTCACCTTTGCAAGCGTTTATTTACTGATGTATGCGGCCACCACTGTGACCACCATCACTTACCGATTCACCAAAACTTAGGTAATATGG
TCTTATTTTTGATTTAATTAAATATACGTGTAGCTCATGTATTTCACAGTTTAATATGAGAAGTGCTTTGGTCTTTATTTAGAAATTGGG
TGATGTTTTTGTGCCCAGCAACATGCTGTAGGAATTTAACTCTTGTTTACATCCATTAGCCTCATGGTTTTGCTTCAAGTCTCAGCTTCC
AAGAACCTATCGATGACTTACTGTGCATGGTCTGAGACTAAGTAAAGGAAATTTCCTAAAGCTGTGAAATTTGAATTTTGCTTTAAATAA

>81154_81154_3_SFSWAP-MYO1H_SFSWAP_chr12_132250853_ENST00000541286_MYO1H_chr12_109845599_ENST00000310903_length(amino acids)=1414AA_BP=721
MDAGDAVMYGASGGRAKPERKSGAKEEAGPGGAGGGGSRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDL
SEYDAEYSTWNRDYQLSEEEARIEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQR
EKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEG
RYTVLAENKSDEKKKSGVSSDNEDDDDEEDGNYLHPSLFASKKCNRLEELMKPLKVVDPDHPLAALVRKAQADSSTPTPHNADGAPVQPS
QVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSAL
APVAAIIPPPPDVQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKP
SDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANT
NPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSV
EVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQ
AEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYA
GEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFD
DFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATED
AFEFSKHQLVARIQATYKRCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKNYIL
NLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDINP
KVLQLISHEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQKGDAVLQCGH

--------------------------------------------------------------
>81154_81154_4_SFSWAP-MYO1H_SFSWAP_chr12_132250853_ENST00000541286_MYO1H_chr12_109845599_ENST00000431443_length(transcript)=5536nt_BP=2235nt
CGGGGTCTTTGACTGAAGGGGTAGGCCAAGTGGAGGTATCAGGGACGTCGCGCGGCACAGAAGAGGACCAGCCTGGACGCCGGGGACGCT
GTCATGTACGGCGCGAGCGGGGGCCGCGCCAAACCCGAGAGGAAAAGCGGCGCGAAGGAGGAGGCCGGGCCAGGCGGTGCCGGCGGTGGG
GGCAGCCGAGTGGAGCTCTTGGTTTTCGGCTATGCCTGCAAGCTGTTCCGGGACGACGAGCGGGCCCTGGCTCAGGAACAGGGACAGCAC
CTCATCCCCTGGATGGGGGACCACAAGATCCTCATCGACAGATATGATGGACGTGGTCACCTGCATGACCTTTCTGAGTACGATGCTGAG
TATTCCACGTGGAACAGAGATTATCAGCTGTCTGAAGAGGAGGCGCGAATAGAGGCCCTGTGTGATGAAGAGAGGTATTTAGCCTTGCAT
ACGGACTTGCTTGAGGAGGAGGCAAGGCAAGAGGAAGAATACAAGCGATTGAGTGAAGCACTAGCAGAGGATGGGAGCTACAATGCCGTG
GGGTTCACTTACGGTAGCGACTATTACGACCCGTCAGAGCCGACGGAGGAGGAGGAGCCTTCCAAACAGAGAGAAAAAAATGAGGCCGAA
AATTTAGAGGAAAATGAAGAGCCCTTCGTTGCCCCCTTAGGATTGAGCGTCCCGTCTGACGTGGAGTTGCCACCAACCGCTAAAATGCAC
GCCATCATCGAGCGCACGGCCAGCTTCGTGTGCAGGCAGGGAGCACAGTTTGAGATCATGCTGAAGGCCAAGCAGGCCCGGAACTCCCAG
TTTGACTTTCTGCGCTTCGACCACTACCTCAACCCCTACTATAAGTTCATCCAGAAAGCCATGAAAGAGGGACGCTACACTGTCCTGGCA
GAAAACAAAAGTGACGAGAAAAAAAAATCAGGAGTCAGCTCTGACAATGAAGATGATGATGATGAAGAAGATGGGAATTACCTTCATCCC
TCTCTCTTTGCCTCCAAGAAGTGTAACCGCCTTGAAGAGCTGATGAAGCCCTTGAAGGTAGTGGACCCAGATCATCCCCTCGCAGCACTT
GTTCGTAAGGCACAGGCTGACAGTTCCACTCCCACCCCACACAACGCAGACGGTGCGCCTGTGCAGCCCTCCCAGGTGGAGTACACGGCA
GACTCGACCGTGGCAGCCATGTATTACAGCTACTACATGCTACCGGACGGCACTTACTGCCTGGCGCCGCCCCCTCCCGGAATCGACGTG
ACTACTTACTACAGCACCCTTCCTGCTGGCGTGACCGTGTCTAACTCCCCTGGAGTGACGACCACCGCCCCACCACCTCCTGGGACCACA
CCACTACCGCCCCCAACCACAGCAGAGACTAGCAGCGGGGCCACCTCCACAACCACCACCACAAGTGCACTTGCCCCCGTGGCCGCCATC
ATCCCCCCGCCCCCCGACGTCCAGCCCGTGATTGACAAGCTGGCCGAGTATGTCGCCAGGAACGGCCTGAAGTTCGAGACCAGTGTTCGT
GCCAAGAATGATCAAAGATTTGAGTTCCTGCAGCCGTGGCACCAGTATAATGCTTATTATGAGTTTAAGAAGCAGTTCTTCCTCCAGAAA
GAAGGGGGCGATAGCATGCAGGCTGTGTCTGCACCAGAAGAGGCTCCCACAGACTCTGCTCCCGAGAAGCCAAGTGATGCTGGGGAGGAT
GGCGCGCCTGAAGACGCAGCCGAGGTGGGAGCACGGGCAGGCTCAGGCGGGAAGAAGGAGGCATCGTCCAGTAAGACCGTCCCGGACGGG
AAGCTGGTGAAAGCTTCCTTTGCTCCAATAAGCTTTGCAATCAAGGCCAAAGAAAATGATCTGCTTCCCCTGGAAAAAAATCGTGTTAAG
CTAGATGATGACAGTGATGATGATGAAGAAAGCAAAGAAGGCCAAGAAAGTTCTAGTAGTGCTGCAAACACTAACCCAGCAGTTGCCCCA
CCCTGTGTAGTTGTTGAGGAGAAGAAGCCTCAACTTACCCAGGAGGAGCTAGAAGCAAAGCAAGCAAAGCAAAAGCTGGAAGATCGCCTC
GCAGCTGCTGCCCGGGAAAAGCTGGCCCAGGCGTCTAAGGAGTCAAAAGAGAAACAGCTTCAAGCAGAACGTAAAAGGAAAGCGGCGTTA
TTTTTACAGACCCTCAAAAATCCTCTGCCGGAAGCAGAAGCTGGGAAAATTGAGGAGAGTCCTTTCAGTGTCGAGGTGATCTGCCCGTTG
ACACTAGAACTCTCTGTCTACGCTAGAGATGCAATGGCAAAGGCTGTTTATGGACGAACGTTTACTTGGCTGGTCAACAAAATCAATTCC
TCCTTAGTTAACAAGGTTGGTCAACGCATTTTGGATCCCTTGCTCTTGCTCACGTGGAAAACTGTAATTGGATTACTGGACATCTATGGG
TTTGAAGTCTTTGACAAGAATGGTTTTGAACAGTTCTGTATAAATTACTGCAATGAGAAACTCCAGCAACTGTTAATTGAGAGGACTCTA
AAAGCAGAACAGGCAGAATATGAAATGGAAGGCATAGAGTGGGAGCCAATTAAATATTTCAACAACAAGATCATCTGTGATTTGGTAGAA
GAGAGACATAAAGGAATCATATCTATTCTGGATGAAGAATGCATTCGGCCTGGTCCTGCTACAGACTTGAGTTTCCTGGAGAAATTGGAA
GAGAAAGTGGGCAAACATGCACACTTCGAAACCCGTAAGCTGGCTGGTCCAAAGGGCCGAAAGAGGATTGGCTGGATGGAGTTCCGACTC
CTCCACTATGCAGGAGAGGTCACATACTGCACCAAGGGATTCTTGGAAAAAAACAATGATCTTCTTTACAGACATCTGAAAGAAGTGCTG
TGCAAGTCCAAGAACATTATCCTGAGGGAATGCTTCCTGCTGGCCGAGTTAGAAAACCGGAGGAGGCCCCCAACAGTGGGGACTCAGTTT
AAAAACAGTCTGAGCAGCCTTCTAGAAACCCTCATCTCTAAGGAGCCCTCCTACATCCGTTGCATCAAGCCCAACGACAGGAAAGAACCC
AGCAAATTTGATGACTTCCTCATAAGGCATCAGATCAAATACCTGGGGCTGATGGAGCACCTGCGGGTGAGACGGGCTGGTTTTGCATAC
CGAAGGAAATACGAGCATTTCTTGCAAAGGTACAAGTCCTTATGCCCAGACACCTGGCCGCACTGGCACGGGCCTCCAGCAGAGGGCGTG
GAACGGCTGATCAAGTACATCGGCTACAAACCCGAGGAATACAAGTTAGGCAAAACCAAAATATTCATTCGTTTCCCCAGAACTCTGTTT
GCTACCGAAGATGCCTTTGAATTTAGTAAACATCAACTAGTTGCAAGAATCCAAGCCACTTACAAACGCTGCCTAGGAAGGAGAGAATAC
GTGAAAAAAAGACAAGCAGCCATCAAACTGGAAGCCCACTGGCGTGGGGCCCTGGCTCGGAAGGCAATCCAAAGGAGAAAGTGGGCCGTG
CGGATTATCAGAAAGTTCATTAAAGGATTCATCAGTCGCAACAAACCCCTCTGTCCTGACAACGAGGAATTTATCGTGTTTGTGCGGAAG
AATTACATCTTGAATCTCCGGTATCACCTTCCAAAGACTGTCCTGGACAAGAGCTGGCTGAGGCCTCCTGGCATCTTGGAAAATGCATCA
GATCTGCTCAGGAAAATGTGCGTGAGGAACCTGGTGCAGAAGTACTGCCGCGGGATCACAGCTGAGCGGAAAGCAATGATGCAGCAAAAG
GTAGTTACAAGTGAAATCTTCAGGGGAAGGAAAGACGGCTACACAGAAAGTTTAAATCAACCCTTTGTCAACAGTCGGATAGATGAAGGA
GACATTAATCCGAAAGTGCTTCAGCTAATTAGCCATGAGAAAATCCAGTATGGTGTCCCGGTCATTAAATATGACAGAAAAGGCTTCAAA
GCACGGCAGCGGCAACTCATTCTTACTCAGAAAGCAGCTTACGTGGTGGAACTTGCCAAAATCAAGCAGAAAATAGAGTACTCAGCTCTC
AAAGGTGTCTCCACTAGCAATCTGAGTGATGGAATCTTAGTCATTCATGTTTCACCAGAGGACAGCAAGCAAAAGGGGGATGCCGTTTTG
CAGTGTGGACACGTGTTTGAAGCAGTTACTAAACTCGTCATGCTGGTTAAGAAGGAGAACATTGTCAATGTTGTTCAAGGAAGTTTACAG
TTTTTTATTAGTCCGGGAAAAGAAGGCACAATAGTTTTCGACACTGGACTGGAAGAACAAGTCTATAAAAATAAAAATGGACAATTAACA
GTGGTGTCAGTCCGGAGGAAGTCCTGATAGAGGATGACGTCTGACCTCTACCATCGCCATTTTTGCTCCAACTGAGGAAACTACAGGGGA
AGTGGGGATTGGATCCAGTTAGCTACCTCTTCAAGGTACCAGGCCCGCAGCACTAACAGATCACATCTGAAGAAACTGAGGGGCGTTAGG
CCAAAGCCTAATCCCAGCTCCTCAGCTGCCCCATGGCACCTTATTTAAAATGTCACCTTCTGGAAGCAGACCCCAGGTCACCCGAAGGCG
CAATTCTAAACACCCTCGACAGGATCTATGTTCAGTGCGCAGTCCAACGTGTCATTAGAGGGTGGGCAAGATTCTCTACCTCTGTCAAGC
TGCCCTGAGACATGATGAAATACTGTGTACAGCAAGTTCTCAAATAACATTTCGTTATATGTTGATAAGACATCTGATTCCTGGGCAGGG
CCACTGTCTGGGTGGAGTCTGTATGTTCTCCCCATGTCTCTGGGTTTCTTCTGGGTGCTCTGGTTTCCTCCCACGTCCCCAAGGTGTGTG
TGTCAGGTGCACTGGCGTGTCTATGCGGTCCCAGTCTGAGTGAGTGTGGGTGCGTGAGCCCCGTGAGAGGAGGACATCCTGTCCAGGGTG
GGTCCCGCCTTCTGCCCTGAGCTGCTGGGATTGGGCTCTGGCCATCTGCAACCCTGAACGTGCAGGTTGGAGAACGAATGAATACAAATT
TTATTGTAAAATAAAAATGTATATAAAGCATATGAGCACACAAATGGACAATAAATGCCACAGCGCAAAAGCGTGTAGCGAGCCTGCCAC
GCTTGTGACTGGGGAGGGGCTCCGTATAATCTCACCTTTGCAAGCGTTTATTTACTGATGTATGCGGCCACCACTGTGACCACCATCACT
TACCGATTCACCAAAACTTAGGTAATATGGTCTTATTTTTGATTTAATTAAATATACGTGTAGCTCATGTATTTCACAGTTTAATATGAG
AAGTGCTTTGGTCTTTATTTAGAAATTGGGTGATGTTTTTGTGCCCAGCAACATGCTGTAGGAATTTAACTCTTGTTTACATCCATTAGC
CTCATGGTTTTGCTTCAAGTCTCAGCTTCCAAGAACCTATCGATGACTTACTGTGCATGGTCTGAGACTAAGTAAAGGAAATTTCCTAAA

>81154_81154_4_SFSWAP-MYO1H_SFSWAP_chr12_132250853_ENST00000541286_MYO1H_chr12_109845599_ENST00000431443_length(amino acids)=1424AA_BP=721
MDAGDAVMYGASGGRAKPERKSGAKEEAGPGGAGGGGSRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDL
SEYDAEYSTWNRDYQLSEEEARIEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQR
EKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEG
RYTVLAENKSDEKKKSGVSSDNEDDDDEEDGNYLHPSLFASKKCNRLEELMKPLKVVDPDHPLAALVRKAQADSSTPTPHNADGAPVQPS
QVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSAL
APVAAIIPPPPDVQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKP
SDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANT
NPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSV
EVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKVGQRILDPLLLLTWKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQL
LIERTLKAEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRKLAGPKGRKRIG
WMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKP
NDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIR
FPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEF
IVFVRKNYILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVN
SRIDEGDINPKVLQLISHEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQ

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SFSWAP-MYO1H


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for SFSWAP-MYO1H


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for SFSWAP-MYO1H


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource