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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SGCD-LCP2 (FusionGDB2 ID:81250)

Fusion Gene Summary for SGCD-LCP2

check button Fusion gene summary
Fusion gene informationFusion gene name: SGCD-LCP2
Fusion gene ID: 81250
HgeneTgene
Gene symbol

SGCD

LCP2

Gene ID

6444

3937

Gene namesarcoglycan deltalymphocyte cytosolic protein 2
Synonyms35DAG|CMD1L|DAGD|LGMDR6|SG-delta|SGCDP|SGDSLP-76|SLP76
Cytomap

5q33.2-q33.3

5q35.1

Type of geneprotein-codingprotein-coding
Descriptiondelta-sarcoglycan35 kDa dystrophin-associated glycoproteindelta-SGdystrophin associated glycoprotein, delta sarcoglycanplacental delta sarcoglycansarcoglycan, delta (35kDa dystrophin-associated glycoprotein)lymphocyte cytosolic protein 276 kDa tyrosine phosphoproteinSH2 domain-containing leukocyte protein of 76 kDaSLP-76 tyrosine phosphoprotein
Modification date2020032820200327
UniProtAcc.

Q13094

Ensembl transtripts involved in fusion geneENST00000337851, ENST00000435422, 
ENST00000447401, ENST00000517913, 
ENST00000046794, ENST00000521416, 
Fusion gene scores* DoF score12 X 10 X 6=7202 X 3 X 2=12
# samples 133
** MAII scorelog2(13/720*10)=-2.46948528330122
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/12*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: SGCD [Title/Abstract] AND LCP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSGCD(155771687)-LCP2(169724729), # samples:2
SGCD(155771687)-LCP2(169720376), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneLCP2

GO:0050852

T cell receptor signaling pathway

20551903


check buttonFusion gene breakpoints across SGCD (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LCP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CQ-6221-01ASGCDchr5

155771687

-LCP2chr5

169720376

-
ChimerDB4HNSCTCGA-CQ-6221-01ASGCDchr5

155771687

+LCP2chr5

169724729

-
ChimerDB4HNSCTCGA-CQ-6221SGCDchr5

155771687

+LCP2chr5

169720376

-
ChimerDB4HNSCTCGA-CQ-6221SGCDchr5

155771687

+LCP2chr5

169724729

-


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Fusion Gene ORF analysis for SGCD-LCP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000337851ENST00000046794SGCDchr5

155771687

+LCP2chr5

169724729

-
5CDS-5UTRENST00000435422ENST00000046794SGCDchr5

155771687

+LCP2chr5

169724729

-
5CDS-5UTRENST00000447401ENST00000046794SGCDchr5

155771687

+LCP2chr5

169724729

-
5CDS-5UTRENST00000517913ENST00000046794SGCDchr5

155771687

+LCP2chr5

169724729

-
5CDS-intronENST00000337851ENST00000521416SGCDchr5

155771687

+LCP2chr5

169724729

-
5CDS-intronENST00000337851ENST00000521416SGCDchr5

155771687

+LCP2chr5

169720376

-
5CDS-intronENST00000435422ENST00000521416SGCDchr5

155771687

+LCP2chr5

169724729

-
5CDS-intronENST00000435422ENST00000521416SGCDchr5

155771687

+LCP2chr5

169720376

-
5CDS-intronENST00000447401ENST00000521416SGCDchr5

155771687

+LCP2chr5

169724729

-
5CDS-intronENST00000447401ENST00000521416SGCDchr5

155771687

+LCP2chr5

169720376

-
5CDS-intronENST00000517913ENST00000521416SGCDchr5

155771687

+LCP2chr5

169724729

-
5CDS-intronENST00000517913ENST00000521416SGCDchr5

155771687

+LCP2chr5

169720376

-
In-frameENST00000337851ENST00000046794SGCDchr5

155771687

+LCP2chr5

169720376

-
In-frameENST00000435422ENST00000046794SGCDchr5

155771687

+LCP2chr5

169720376

-
In-frameENST00000447401ENST00000046794SGCDchr5

155771687

+LCP2chr5

169720376

-
In-frameENST00000517913ENST00000046794SGCDchr5

155771687

+LCP2chr5

169720376

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000517913SGCDchr5155771687+ENST00000046794LCP2chr5169720376-45385543622077571
ENST00000435422SGCDchr5155771687+ENST00000046794LCP2chr5169720376-46606763522199615
ENST00000447401SGCDchr5155771687+ENST00000046794LCP2chr5169720376-46957115192234571
ENST00000337851SGCDchr5155771687+ENST00000046794LCP2chr5169720376-46957115192234571

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000517913ENST00000046794SGCDchr5155771687+LCP2chr5169720376-0.0009282960.9990717
ENST00000435422ENST00000046794SGCDchr5155771687+LCP2chr5169720376-0.0006596970.99934024
ENST00000447401ENST00000046794SGCDchr5155771687+LCP2chr5169720376-0.0012158250.99878424
ENST00000337851ENST00000046794SGCDchr5155771687+LCP2chr5169720376-0.0012158250.99878424

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Fusion Genomic Features for SGCD-LCP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SGCD-LCP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:155771687/chr5:169724729)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.LCP2

Q13094

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Involved in T-cell antigen receptor mediated signaling.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSGCDchr5:155771687chr5:169720376ENST00000337851+391_3564291.0Topological domainCytoplasmic
HgeneSGCDchr5:155771687chr5:169720376ENST00000435422+281_3563290.0Topological domainCytoplasmic
HgeneSGCDchr5:155771687chr5:169720376ENST00000447401+381_3564257.0Topological domainCytoplasmic
HgeneSGCDchr5:155771687chr5:169720376ENST00000517913+5101_3564257.0Topological domainCytoplasmic
HgeneSGCDchr5:155771687chr5:169720376ENST00000337851+3936_5664291.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneSGCDchr5:155771687chr5:169720376ENST00000435422+2836_5663290.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneSGCDchr5:155771687chr5:169720376ENST00000447401+3836_5664257.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneSGCDchr5:155771687chr5:169720376ENST00000517913+51036_5664257.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneLCP2chr5:155771687chr5:169720376ENST00000046794021133_13626534.0Compositional biasNote=Poly-Glu
TgeneLCP2chr5:155771687chr5:169720376ENST00000046794021198_20126534.0Compositional biasNote=Poly-Pro
TgeneLCP2chr5:155771687chr5:169720376ENST00000046794021422_53026534.0DomainSH2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSGCDchr5:155771687chr5:169720376ENST00000337851+3957_28964291.0Topological domainExtracellular
HgeneSGCDchr5:155771687chr5:169720376ENST00000435422+2857_28963290.0Topological domainExtracellular
HgeneSGCDchr5:155771687chr5:169720376ENST00000447401+3857_28964257.0Topological domainExtracellular
HgeneSGCDchr5:155771687chr5:169720376ENST00000517913+51057_28964257.0Topological domainExtracellular
TgeneLCP2chr5:155771687chr5:169720376ENST0000004679402115_8126534.0DomainNote=SAM


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Fusion Gene Sequence for SGCD-LCP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>81250_81250_1_SGCD-LCP2_SGCD_chr5_155771687_ENST00000337851_LCP2_chr5_169720376_ENST00000046794_length(transcript)=4695nt_BP=711nt
AGAGAGGACTTATCTCCAGCATCTAGCACTACAGAGCAGAGGCTGTGTGGAGAATGGCTGAAAAATCAGAATTGGTTGTAGAAGCAGTTT
TCTTTCTGGTTGTGAGTATGAGCCCGGCAGACACCATGAGCGCTGTTGCAGGGGAGTCGGCCTGTGCTTGACACATGTGTTTCCCATTGA
TAGCTGGAGACAGCCCAGTAGCTGTGAGTCGGTCTGACAAAGCCATATTGAAGTACGGAGTACGGTTTCAAAGCAGTCAGAAAAAGAACG
GGAATGCTGTTCAGGAAATTCTTCAGGCATGGGCAGGGACTTGGCTGCAGTTCTGCAGTTGGAAAATCTGACTGGGGCAGCTTCTGAGCG
CAGGCTGGGCCTGCACACACTCAGCGGGCCGAGTGGCCACCTCCTTCAGAGCTGCTCAGCACGCCCTGGGATCGCGGGCGGTTTTCATCG
GCCGGTTTGTGAAACGGACAAGAGAGAGACATTACTGCCGGGAGTGTTGAGTGAAGGGACCAGGTGGAGATGATGCCTCAGGAGCAGTAC
ACTCACCACCGGAGCACCATGCCTGGCTCTGTGGGGCCACAGGTATACAAGGTGGGGATTTATGGCTGGCGGAAACGATGCCTGTATTTC
TTTGTCCTGCTCCTCATGATTTTAATACTGGTGAACTTGGCCATGACCATCTGGATTCTCAAAGTCATGAACTTCACAATTCTCAACTAT
AAGGACTGTGAGAAGGCAGTGAAGAAGTACCACATCGATGGGGCTCGCTTCTTGAACCTGACAGAAAATGACATCCAGAAGTTCCCCAAG
CTCCGGGTGCCGATTCTCAGTAAGTTAAGTCAGGAAATCAACAAGAACGAAGAGAGGAGGAGCATCTTCACACGCAAACCCCAAGTCCCG
CGGTTTCCTGAAGAGACAGAAAGCCACGAAGAGGACAATGGGGGCTGGTCGTCCTTTGAAGAAGACGATTATGAAAGTCCCAATGATGAC
CAGGATGGGGAGGATGATGGAGACTATGAGTCCCCCAATGAGGAGGAAGAGGCACCCGTGGAAGATGACGCGGATTATGAGCCGCCACCC
TCCAATGACGAGGAAGCTCTGCAGAACTCCATCCTGCCTGCCAAGCCTTTCCCCAACTCCAACTCCATGTACATCGACCGGCCCCCCTCT
GGGAAAACCCCCCAGCAGCCTCCTGTGCCCCCCCAGAGACCGATGGCCGCCCTCCCGCCCCCACCAGCCGGCCGGAATCACTCGCCACTG
CCCCCACCCCAGACCAACCACGAAGAACCCAGCAGAAGCAGAAACCACAAAACGGCAAAGCTCCCTGCTCCTTCAATAGACAGAAGCACG
AAACCTCCCCTAGATCGTTCATTAGCTCCGTTTGATAGAGAACCCTTCACACTAGGAAAGAAACCACCATTTTCTGACAAGCCCTCGATT
CCAGCGGGAAGGTCACTCGGGGAGCATTTACCCAAGATTCAAAAGCCTCCTTTACCACCGACCACGGAAAGACATGAAAGGAGCAGCCCC
CTGCCAGGGAAGAAGCCACCTGTGCCAAAGCATGGATGGGGACCAGACAGAAGAGAGAATGATGAAGATGATGTGCATCAGAGACCTTTG
CCCCAGCCAGCACTACTTCCTATGAGCTCCAACACTTTCCCTTCAAGATCTACTAAGCCAAGTCCCATGAACCCTCTCCCATCCTCTCAC
ATGCCTGGAGCATTCTCAGAAAGTAACAGCAGTTTTCCACAGAGTGCCTCCCTGCCACCATACTTCTCTCAAGGCCCTAGCAACAGACCA
CCTATCAGAGCCGAAGGCAGAAACTTCCCCTTGCCACTTCCAAACAAACCTCGGCCCCCATCCCCCGCGGAGGAAGAGAATTCATTAAAT
GAAGAGTGGTACGTTTCTTATATTACCCGACCAGAGGCAGAAGCTGCTCTTAGAAAGATAAACCAGGATGGCACATTTCTGGTCAGAGAC
AGCTCTAAAAAAACAACAACCAATCCATATGTCCTCATGGTGTTGTACAAAGATAAAGTTTACAACATCCAGATCCGTTATCAGAAGGAA
AGTCAAGTTTACTTGTTGGGAACTGGACTCCGAGGGAAAGAGGACTTTCTGTCTGTGTCAGATATTATTGACTACTTCAGGAAAATGCCA
CTTCTGCTCATTGATGGGAAAAACCGAGGTTCCAGATACCAGTGCACATTAACGCATGCTGCAGGGTACCCATAGCAAGTTATAGCCGAG
CAAATGAACCGTCCTCCTGCCTCTGTTGCCAACACGAGATCAATCAGCCTTGGTCAATGGACAAACACTTAGGACTGAACTGAACCCCTC
CCCATGAACACAAGGGTTTTATCCTTTCCTTTAAAAACAGTGTTTGAAATGAAGACTGTCAACTATCCCATAATTTATTTATTCTTCTTC
AATGTTTGTAAAGTGCATGAGTCATGTTCACACTTGAAGTCTAGTAGTGCACTGTAATAATTCATTTTTTAAAAGATTATTTAATGCCCA
TTTCAAAATACAGTAGTTTACACAGCTACAGAAACAATTTGGGGCAAGTTTTAAAACACTGAAACAGTAATAGTTATTGGTGTCACATAA
AACTGATTTGTTTTTTACAGCCAAACCTCTGTCAGTCAGAGGCATTCATTAGTTTTATACATGTAATTTGAAAATCACTAAACCTCGTTT
TCTCAGCAGCAATAATTTAAGAGGCTTCAAAAATATAATTTCACTCTTATTTAGTATTTTTTCCTGGGGGCATTTTTACGTAATTTTTTT
ATGAAAAGACAAATGCATGTTGAGATAACTTCTGGGATTAAAATAGTCTTTTGCTTTACTTTTTTGGTTTCCTAAAACAACTTTATTGAC
TTTTAGTCCATACTGTTATATTTTTGTCTTAAAGAAAATTTAAACTACAAATACCAAAAGAAAACATTTTAAATTTAGGGATGAGACTTT
GGTGTATCGTGGGTCTAGGTTTAATGAACACATCTGGGGTTAAGTTGGCATTTCTTCACATCTCCACACCCACACCAACCATCACAGCCC
CCCACCAACCTTCTCCCAACCCCAAAAGCATTGTCCAGGGATATAGATTTTACCAAAGGCTTCCTGGGAAGACGAGGGAGCAACACTTTA
GATTAAATGTGATCAGACTTTCCTATTAGATATGGCTCTTCTGTCTCTTGTTATCCCCCTGACAGCTCTGCCATAAAGTCCCTTCTCCTC
ATCCTTCCCAAACAGGCTGTATAAGTGCTTTGAGGTAATTAAACTCTTTCCTCCAGTTTACAAATATCACTTAACAAAAAATATAGGCAT
TCAGCCAGATTAAAAAACTGGTATTCAGCCAAATAGTGACAATCAGTTGTTCTTCAAGTTTTTCCCTTTGGGACCTTGGTTGTTATTGCA
CAACTTTTATTAGCAACAATTTTTGGCGTCTCTGCTTAATCTACAAGTTTTCGAAATGGAAAAGAGTATCTTGCAGCTTCATTTTCATGA
GCTAATAAAAGGGGTATTGGAAGGAATCTAAGAAGTCACCATTTTAAAACTGATGATATGTTAAAATAAGGAGTATGCAGAAGGTAGAGA
CTTTTAACTGATGATAAAAATGGTGTTTCACAAAATCTCATCCTTAACAACCAGAAGTTCTCAGTTTAGGGTCCAAAACTTGGGAGTTTA
AGGCTGAAAACCCTGCATTCATTTACACGTCTACACAACGGGCTATTCAGCAAGTATTTACTTAGTGGCTCTTCTGTGTTAAACAAGTGA
GCTAGGTACAAGGTAGTAAGGATAGCATACACCATAGGTTCTAGTATCGAGTAAGCTCCACTTGTCTTGCTTTGCCGTATTCTATCTTTA
CAATTCAAAAATATCTAAAATGAAGGACCTGATAGATTTCAAAGCAACTATTTGGTAGCGAATCATGTTTATAAAACAAACCAAAGCTCA
TTTTAAGTCTATTAGTGGAAAGTGCCATCAGGATTAAGATGTTCTGTTCCATGGCTATGACTGAAATCAATGTTGGGAAGCTAATGTTTT
CATGACTAGCATTCTCTCTCTGTTCAAGCACCGACAACTCCTTTTGGCTGGGCCTTGCCTCTTTTGGCCACAGACCTTCTATATGACCCC
AGGTGCATCAGTCACAGTTGCTCAGAACCCTGCTCAGTGATAAACATCTTACTAAAGCTGGGTCAATCAGGGTCACTCTCTGGAATGTTA
AACATGAAGCCTGAGACAAGATCTCTCTTTTATCTGGGGTCCCCAAAGGCAATGCTGTACACTTGGAGCTGCCTGCTGCCCTGCAACTAC
TCCCATTTACCAATTATCTGGAAGAACCAGTCTACAATAGAAGACAACGAGGCCAACACACAAAAACACAGTAAAAGTATGGACAAATTA
GTGGGATCCCTGAAATCTATTCCAACTATGTGCTTCCAAGTCACATGACTCAATAAATGCTTCAGCTGGTTGAGTTGTGCTTGGCGTTCA
CTACCAGGAGAGTTCTGATTAATAAAAACTCATTCCATCAATTAATAATTTAGTAGCTCTCTTTCAACCTGAGCCAAATTCAAGCATAAG
CTAAAGGATAAGCAGTGACCCATGGCCAATTTCCTATGTCATACACTTGCCATTAGTGACGTAAGTTAAGCCATTCTTCAAAACATTAAA

>81250_81250_1_SGCD-LCP2_SGCD_chr5_155771687_ENST00000337851_LCP2_chr5_169720376_ENST00000046794_length(amino acids)=571AA_BP=64
MMPQEQYTHHRSTMPGSVGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTILNYKDCEKAVKKYHIDGARFLNLTEN
DIQKFPKLRVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDD
ADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPA
PSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDED
DVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPA
EEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDII

--------------------------------------------------------------
>81250_81250_2_SGCD-LCP2_SGCD_chr5_155771687_ENST00000435422_LCP2_chr5_169720376_ENST00000046794_length(transcript)=4660nt_BP=676nt
GAGCAGAAGAAAGAGAGGACTTATCTCCAGCATCTAGCACTACAGAGCAGAGGCTGTGTGGAGAATGGCTGAAAAATCAGAATTGGTTGT
AGAAGCAGTTTTCTTTCTGGTTGTGAGTATGAGCCCGGCAGACACCATGAGCGCTGTTGCAGGGGAGTCGGCCTGTGCTTGACACATGTG
TTTCCCATTGATAGCTGGAGACAGCCCAGTAGCTGTGAGTCGGTCTGACAAAGCCATATTGAAGTACGGAGTACGGTTTCAAAGCAGTCA
GAAAAAGAACGGGAATGCTGTTCAGGAAATTCTTCAGGCATGGGCAGGGACTTGGCTGCAGTTCTGCAGTTGGAAAATCTGACTGGGGCA
GCTTCTGAGCGCAGGCTGGGCCTGCACACACTCAGCGGGCCGAGTGGCCACCTCCTTCAGAGCTGCTCAGCACGCCCTGGGATCGCGGGC
GGTTTTCATCGGCCGGTTTGTGAAACGGACAAGAGAGATGCCTCAGGAGCAGTACACTCACCACCGGAGCACCATGCCTGGCTCTGTGGG
GCCACAGGTATACAAGGTGGGGATTTATGGCTGGCGGAAACGATGCCTGTATTTCTTTGTCCTGCTCCTCATGATTTTAATACTGGTGAA
CTTGGCCATGACCATCTGGATTCTCAAAGTCATGAACTTCACAATTCTCAACTATAAGGACTGTGAGAAGGCAGTGAAGAAGTACCACAT
CGATGGGGCTCGCTTCTTGAACCTGACAGAAAATGACATCCAGAAGTTCCCCAAGCTCCGGGTGCCGATTCTCAGTAAGTTAAGTCAGGA
AATCAACAAGAACGAAGAGAGGAGGAGCATCTTCACACGCAAACCCCAAGTCCCGCGGTTTCCTGAAGAGACAGAAAGCCACGAAGAGGA
CAATGGGGGCTGGTCGTCCTTTGAAGAAGACGATTATGAAAGTCCCAATGATGACCAGGATGGGGAGGATGATGGAGACTATGAGTCCCC
CAATGAGGAGGAAGAGGCACCCGTGGAAGATGACGCGGATTATGAGCCGCCACCCTCCAATGACGAGGAAGCTCTGCAGAACTCCATCCT
GCCTGCCAAGCCTTTCCCCAACTCCAACTCCATGTACATCGACCGGCCCCCCTCTGGGAAAACCCCCCAGCAGCCTCCTGTGCCCCCCCA
GAGACCGATGGCCGCCCTCCCGCCCCCACCAGCCGGCCGGAATCACTCGCCACTGCCCCCACCCCAGACCAACCACGAAGAACCCAGCAG
AAGCAGAAACCACAAAACGGCAAAGCTCCCTGCTCCTTCAATAGACAGAAGCACGAAACCTCCCCTAGATCGTTCATTAGCTCCGTTTGA
TAGAGAACCCTTCACACTAGGAAAGAAACCACCATTTTCTGACAAGCCCTCGATTCCAGCGGGAAGGTCACTCGGGGAGCATTTACCCAA
GATTCAAAAGCCTCCTTTACCACCGACCACGGAAAGACATGAAAGGAGCAGCCCCCTGCCAGGGAAGAAGCCACCTGTGCCAAAGCATGG
ATGGGGACCAGACAGAAGAGAGAATGATGAAGATGATGTGCATCAGAGACCTTTGCCCCAGCCAGCACTACTTCCTATGAGCTCCAACAC
TTTCCCTTCAAGATCTACTAAGCCAAGTCCCATGAACCCTCTCCCATCCTCTCACATGCCTGGAGCATTCTCAGAAAGTAACAGCAGTTT
TCCACAGAGTGCCTCCCTGCCACCATACTTCTCTCAAGGCCCTAGCAACAGACCACCTATCAGAGCCGAAGGCAGAAACTTCCCCTTGCC
ACTTCCAAACAAACCTCGGCCCCCATCCCCCGCGGAGGAAGAGAATTCATTAAATGAAGAGTGGTACGTTTCTTATATTACCCGACCAGA
GGCAGAAGCTGCTCTTAGAAAGATAAACCAGGATGGCACATTTCTGGTCAGAGACAGCTCTAAAAAAACAACAACCAATCCATATGTCCT
CATGGTGTTGTACAAAGATAAAGTTTACAACATCCAGATCCGTTATCAGAAGGAAAGTCAAGTTTACTTGTTGGGAACTGGACTCCGAGG
GAAAGAGGACTTTCTGTCTGTGTCAGATATTATTGACTACTTCAGGAAAATGCCACTTCTGCTCATTGATGGGAAAAACCGAGGTTCCAG
ATACCAGTGCACATTAACGCATGCTGCAGGGTACCCATAGCAAGTTATAGCCGAGCAAATGAACCGTCCTCCTGCCTCTGTTGCCAACAC
GAGATCAATCAGCCTTGGTCAATGGACAAACACTTAGGACTGAACTGAACCCCTCCCCATGAACACAAGGGTTTTATCCTTTCCTTTAAA
AACAGTGTTTGAAATGAAGACTGTCAACTATCCCATAATTTATTTATTCTTCTTCAATGTTTGTAAAGTGCATGAGTCATGTTCACACTT
GAAGTCTAGTAGTGCACTGTAATAATTCATTTTTTAAAAGATTATTTAATGCCCATTTCAAAATACAGTAGTTTACACAGCTACAGAAAC
AATTTGGGGCAAGTTTTAAAACACTGAAACAGTAATAGTTATTGGTGTCACATAAAACTGATTTGTTTTTTACAGCCAAACCTCTGTCAG
TCAGAGGCATTCATTAGTTTTATACATGTAATTTGAAAATCACTAAACCTCGTTTTCTCAGCAGCAATAATTTAAGAGGCTTCAAAAATA
TAATTTCACTCTTATTTAGTATTTTTTCCTGGGGGCATTTTTACGTAATTTTTTTATGAAAAGACAAATGCATGTTGAGATAACTTCTGG
GATTAAAATAGTCTTTTGCTTTACTTTTTTGGTTTCCTAAAACAACTTTATTGACTTTTAGTCCATACTGTTATATTTTTGTCTTAAAGA
AAATTTAAACTACAAATACCAAAAGAAAACATTTTAAATTTAGGGATGAGACTTTGGTGTATCGTGGGTCTAGGTTTAATGAACACATCT
GGGGTTAAGTTGGCATTTCTTCACATCTCCACACCCACACCAACCATCACAGCCCCCCACCAACCTTCTCCCAACCCCAAAAGCATTGTC
CAGGGATATAGATTTTACCAAAGGCTTCCTGGGAAGACGAGGGAGCAACACTTTAGATTAAATGTGATCAGACTTTCCTATTAGATATGG
CTCTTCTGTCTCTTGTTATCCCCCTGACAGCTCTGCCATAAAGTCCCTTCTCCTCATCCTTCCCAAACAGGCTGTATAAGTGCTTTGAGG
TAATTAAACTCTTTCCTCCAGTTTACAAATATCACTTAACAAAAAATATAGGCATTCAGCCAGATTAAAAAACTGGTATTCAGCCAAATA
GTGACAATCAGTTGTTCTTCAAGTTTTTCCCTTTGGGACCTTGGTTGTTATTGCACAACTTTTATTAGCAACAATTTTTGGCGTCTCTGC
TTAATCTACAAGTTTTCGAAATGGAAAAGAGTATCTTGCAGCTTCATTTTCATGAGCTAATAAAAGGGGTATTGGAAGGAATCTAAGAAG
TCACCATTTTAAAACTGATGATATGTTAAAATAAGGAGTATGCAGAAGGTAGAGACTTTTAACTGATGATAAAAATGGTGTTTCACAAAA
TCTCATCCTTAACAACCAGAAGTTCTCAGTTTAGGGTCCAAAACTTGGGAGTTTAAGGCTGAAAACCCTGCATTCATTTACACGTCTACA
CAACGGGCTATTCAGCAAGTATTTACTTAGTGGCTCTTCTGTGTTAAACAAGTGAGCTAGGTACAAGGTAGTAAGGATAGCATACACCAT
AGGTTCTAGTATCGAGTAAGCTCCACTTGTCTTGCTTTGCCGTATTCTATCTTTACAATTCAAAAATATCTAAAATGAAGGACCTGATAG
ATTTCAAAGCAACTATTTGGTAGCGAATCATGTTTATAAAACAAACCAAAGCTCATTTTAAGTCTATTAGTGGAAAGTGCCATCAGGATT
AAGATGTTCTGTTCCATGGCTATGACTGAAATCAATGTTGGGAAGCTAATGTTTTCATGACTAGCATTCTCTCTCTGTTCAAGCACCGAC
AACTCCTTTTGGCTGGGCCTTGCCTCTTTTGGCCACAGACCTTCTATATGACCCCAGGTGCATCAGTCACAGTTGCTCAGAACCCTGCTC
AGTGATAAACATCTTACTAAAGCTGGGTCAATCAGGGTCACTCTCTGGAATGTTAAACATGAAGCCTGAGACAAGATCTCTCTTTTATCT
GGGGTCCCCAAAGGCAATGCTGTACACTTGGAGCTGCCTGCTGCCCTGCAACTACTCCCATTTACCAATTATCTGGAAGAACCAGTCTAC
AATAGAAGACAACGAGGCCAACACACAAAAACACAGTAAAAGTATGGACAAATTAGTGGGATCCCTGAAATCTATTCCAACTATGTGCTT
CCAAGTCACATGACTCAATAAATGCTTCAGCTGGTTGAGTTGTGCTTGGCGTTCACTACCAGGAGAGTTCTGATTAATAAAAACTCATTC
CATCAATTAATAATTTAGTAGCTCTCTTTCAACCTGAGCCAAATTCAAGCATAAGCTAAAGGATAAGCAGTGACCCATGGCCAATTTCCT

>81250_81250_2_SGCD-LCP2_SGCD_chr5_155771687_ENST00000435422_LCP2_chr5_169720376_ENST00000046794_length(amino acids)=615AA_BP=108
MGQLLSAGWACTHSAGRVATSFRAAQHALGSRAVFIGRFVKRTREMPQEQYTHHRSTMPGSVGPQVYKVGIYGWRKRCLYFFVLLLMILI
LVNLAMTIWILKVMNFTILNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKLRVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESH
EEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPV
PPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEH
LPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESN
SSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNP

--------------------------------------------------------------
>81250_81250_3_SGCD-LCP2_SGCD_chr5_155771687_ENST00000447401_LCP2_chr5_169720376_ENST00000046794_length(transcript)=4695nt_BP=711nt
AGAGAGGACTTATCTCCAGCATCTAGCACTACAGAGCAGAGGCTGTGTGGAGAATGGCTGAAAAATCAGAATTGGTTGTAGAAGCAGTTT
TCTTTCTGGTTGTGAGTATGAGCCCGGCAGACACCATGAGCGCTGTTGCAGGGGAGTCGGCCTGTGCTTGACACATGTGTTTCCCATTGA
TAGCTGGAGACAGCCCAGTAGCTGTGAGTCGGTCTGACAAAGCCATATTGAAGTACGGAGTACGGTTTCAAAGCAGTCAGAAAAAGAACG
GGAATGCTGTTCAGGAAATTCTTCAGGCATGGGCAGGGACTTGGCTGCAGTTCTGCAGTTGGAAAATCTGACTGGGGCAGCTTCTGAGCG
CAGGCTGGGCCTGCACACACTCAGCGGGCCGAGTGGCCACCTCCTTCAGAGCTGCTCAGCACGCCCTGGGATCGCGGGCGGTTTTCATCG
GCCGGTTTGTGAAACGGACAAGAGAGAGACATTACTGCCGGGAGTGTTGAGTGAAGGGACCAGGTGGAGATGATGCCTCAGGAGCAGTAC
ACTCACCACCGGAGCACCATGCCTGGCTCTGTGGGGCCACAGGTATACAAGGTGGGGATTTATGGCTGGCGGAAACGATGCCTGTATTTC
TTTGTCCTGCTCCTCATGATTTTAATACTGGTGAACTTGGCCATGACCATCTGGATTCTCAAAGTCATGAACTTCACAATTCTCAACTAT
AAGGACTGTGAGAAGGCAGTGAAGAAGTACCACATCGATGGGGCTCGCTTCTTGAACCTGACAGAAAATGACATCCAGAAGTTCCCCAAG
CTCCGGGTGCCGATTCTCAGTAAGTTAAGTCAGGAAATCAACAAGAACGAAGAGAGGAGGAGCATCTTCACACGCAAACCCCAAGTCCCG
CGGTTTCCTGAAGAGACAGAAAGCCACGAAGAGGACAATGGGGGCTGGTCGTCCTTTGAAGAAGACGATTATGAAAGTCCCAATGATGAC
CAGGATGGGGAGGATGATGGAGACTATGAGTCCCCCAATGAGGAGGAAGAGGCACCCGTGGAAGATGACGCGGATTATGAGCCGCCACCC
TCCAATGACGAGGAAGCTCTGCAGAACTCCATCCTGCCTGCCAAGCCTTTCCCCAACTCCAACTCCATGTACATCGACCGGCCCCCCTCT
GGGAAAACCCCCCAGCAGCCTCCTGTGCCCCCCCAGAGACCGATGGCCGCCCTCCCGCCCCCACCAGCCGGCCGGAATCACTCGCCACTG
CCCCCACCCCAGACCAACCACGAAGAACCCAGCAGAAGCAGAAACCACAAAACGGCAAAGCTCCCTGCTCCTTCAATAGACAGAAGCACG
AAACCTCCCCTAGATCGTTCATTAGCTCCGTTTGATAGAGAACCCTTCACACTAGGAAAGAAACCACCATTTTCTGACAAGCCCTCGATT
CCAGCGGGAAGGTCACTCGGGGAGCATTTACCCAAGATTCAAAAGCCTCCTTTACCACCGACCACGGAAAGACATGAAAGGAGCAGCCCC
CTGCCAGGGAAGAAGCCACCTGTGCCAAAGCATGGATGGGGACCAGACAGAAGAGAGAATGATGAAGATGATGTGCATCAGAGACCTTTG
CCCCAGCCAGCACTACTTCCTATGAGCTCCAACACTTTCCCTTCAAGATCTACTAAGCCAAGTCCCATGAACCCTCTCCCATCCTCTCAC
ATGCCTGGAGCATTCTCAGAAAGTAACAGCAGTTTTCCACAGAGTGCCTCCCTGCCACCATACTTCTCTCAAGGCCCTAGCAACAGACCA
CCTATCAGAGCCGAAGGCAGAAACTTCCCCTTGCCACTTCCAAACAAACCTCGGCCCCCATCCCCCGCGGAGGAAGAGAATTCATTAAAT
GAAGAGTGGTACGTTTCTTATATTACCCGACCAGAGGCAGAAGCTGCTCTTAGAAAGATAAACCAGGATGGCACATTTCTGGTCAGAGAC
AGCTCTAAAAAAACAACAACCAATCCATATGTCCTCATGGTGTTGTACAAAGATAAAGTTTACAACATCCAGATCCGTTATCAGAAGGAA
AGTCAAGTTTACTTGTTGGGAACTGGACTCCGAGGGAAAGAGGACTTTCTGTCTGTGTCAGATATTATTGACTACTTCAGGAAAATGCCA
CTTCTGCTCATTGATGGGAAAAACCGAGGTTCCAGATACCAGTGCACATTAACGCATGCTGCAGGGTACCCATAGCAAGTTATAGCCGAG
CAAATGAACCGTCCTCCTGCCTCTGTTGCCAACACGAGATCAATCAGCCTTGGTCAATGGACAAACACTTAGGACTGAACTGAACCCCTC
CCCATGAACACAAGGGTTTTATCCTTTCCTTTAAAAACAGTGTTTGAAATGAAGACTGTCAACTATCCCATAATTTATTTATTCTTCTTC
AATGTTTGTAAAGTGCATGAGTCATGTTCACACTTGAAGTCTAGTAGTGCACTGTAATAATTCATTTTTTAAAAGATTATTTAATGCCCA
TTTCAAAATACAGTAGTTTACACAGCTACAGAAACAATTTGGGGCAAGTTTTAAAACACTGAAACAGTAATAGTTATTGGTGTCACATAA
AACTGATTTGTTTTTTACAGCCAAACCTCTGTCAGTCAGAGGCATTCATTAGTTTTATACATGTAATTTGAAAATCACTAAACCTCGTTT
TCTCAGCAGCAATAATTTAAGAGGCTTCAAAAATATAATTTCACTCTTATTTAGTATTTTTTCCTGGGGGCATTTTTACGTAATTTTTTT
ATGAAAAGACAAATGCATGTTGAGATAACTTCTGGGATTAAAATAGTCTTTTGCTTTACTTTTTTGGTTTCCTAAAACAACTTTATTGAC
TTTTAGTCCATACTGTTATATTTTTGTCTTAAAGAAAATTTAAACTACAAATACCAAAAGAAAACATTTTAAATTTAGGGATGAGACTTT
GGTGTATCGTGGGTCTAGGTTTAATGAACACATCTGGGGTTAAGTTGGCATTTCTTCACATCTCCACACCCACACCAACCATCACAGCCC
CCCACCAACCTTCTCCCAACCCCAAAAGCATTGTCCAGGGATATAGATTTTACCAAAGGCTTCCTGGGAAGACGAGGGAGCAACACTTTA
GATTAAATGTGATCAGACTTTCCTATTAGATATGGCTCTTCTGTCTCTTGTTATCCCCCTGACAGCTCTGCCATAAAGTCCCTTCTCCTC
ATCCTTCCCAAACAGGCTGTATAAGTGCTTTGAGGTAATTAAACTCTTTCCTCCAGTTTACAAATATCACTTAACAAAAAATATAGGCAT
TCAGCCAGATTAAAAAACTGGTATTCAGCCAAATAGTGACAATCAGTTGTTCTTCAAGTTTTTCCCTTTGGGACCTTGGTTGTTATTGCA
CAACTTTTATTAGCAACAATTTTTGGCGTCTCTGCTTAATCTACAAGTTTTCGAAATGGAAAAGAGTATCTTGCAGCTTCATTTTCATGA
GCTAATAAAAGGGGTATTGGAAGGAATCTAAGAAGTCACCATTTTAAAACTGATGATATGTTAAAATAAGGAGTATGCAGAAGGTAGAGA
CTTTTAACTGATGATAAAAATGGTGTTTCACAAAATCTCATCCTTAACAACCAGAAGTTCTCAGTTTAGGGTCCAAAACTTGGGAGTTTA
AGGCTGAAAACCCTGCATTCATTTACACGTCTACACAACGGGCTATTCAGCAAGTATTTACTTAGTGGCTCTTCTGTGTTAAACAAGTGA
GCTAGGTACAAGGTAGTAAGGATAGCATACACCATAGGTTCTAGTATCGAGTAAGCTCCACTTGTCTTGCTTTGCCGTATTCTATCTTTA
CAATTCAAAAATATCTAAAATGAAGGACCTGATAGATTTCAAAGCAACTATTTGGTAGCGAATCATGTTTATAAAACAAACCAAAGCTCA
TTTTAAGTCTATTAGTGGAAAGTGCCATCAGGATTAAGATGTTCTGTTCCATGGCTATGACTGAAATCAATGTTGGGAAGCTAATGTTTT
CATGACTAGCATTCTCTCTCTGTTCAAGCACCGACAACTCCTTTTGGCTGGGCCTTGCCTCTTTTGGCCACAGACCTTCTATATGACCCC
AGGTGCATCAGTCACAGTTGCTCAGAACCCTGCTCAGTGATAAACATCTTACTAAAGCTGGGTCAATCAGGGTCACTCTCTGGAATGTTA
AACATGAAGCCTGAGACAAGATCTCTCTTTTATCTGGGGTCCCCAAAGGCAATGCTGTACACTTGGAGCTGCCTGCTGCCCTGCAACTAC
TCCCATTTACCAATTATCTGGAAGAACCAGTCTACAATAGAAGACAACGAGGCCAACACACAAAAACACAGTAAAAGTATGGACAAATTA
GTGGGATCCCTGAAATCTATTCCAACTATGTGCTTCCAAGTCACATGACTCAATAAATGCTTCAGCTGGTTGAGTTGTGCTTGGCGTTCA
CTACCAGGAGAGTTCTGATTAATAAAAACTCATTCCATCAATTAATAATTTAGTAGCTCTCTTTCAACCTGAGCCAAATTCAAGCATAAG
CTAAAGGATAAGCAGTGACCCATGGCCAATTTCCTATGTCATACACTTGCCATTAGTGACGTAAGTTAAGCCATTCTTCAAAACATTAAA

>81250_81250_3_SGCD-LCP2_SGCD_chr5_155771687_ENST00000447401_LCP2_chr5_169720376_ENST00000046794_length(amino acids)=571AA_BP=64
MMPQEQYTHHRSTMPGSVGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTILNYKDCEKAVKKYHIDGARFLNLTEN
DIQKFPKLRVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDD
ADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPA
PSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDED
DVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPA
EEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDII

--------------------------------------------------------------
>81250_81250_4_SGCD-LCP2_SGCD_chr5_155771687_ENST00000517913_LCP2_chr5_169720376_ENST00000046794_length(transcript)=4538nt_BP=554nt
GTGATATCTATTGAAGCTGGGAGGGTCACAGTATCAGTGAGTGGTCCCCCAATTTCTTCTTGAGCATCGATGAATTAGCAGTGGTGTAAT
ATTGTGGATCTGACTTCATGTGTCACTAAGAACAGGAGATCCAAGACTGCTCTTCTGGGGATGAGACTTGGAAGAAACCTCCATCCTCAG
GGATTTGAAGAAGGTTATACTGGAACCTGTGTGAAGGCTGAGACAACCGTCCCTTTTGTGGTGGCCTGAGGGGATTTTCTTAATCCCAAT
GTTGCCCTGAAATTTATGTCCAGGATTCAAAAAGTTTAGGACTGCTAAGAGACATTACTGCCGGGAGTGTTGAGTGAAGGGACCAGGTGG
AGATGATGCCTCAGGAGCAGTACACTCACCACCGGAGCACCATGCCTGGCTCTGTGGGGCCACAGGTATACAAGGTGGGGATTTATGGCT
GGCGGAAACGATGCCTGTATTTCTTTGTCCTGCTCCTCATGATTTTAATACTGGTGAACTTGGCCATGACCATCTGGATTCTCAAAGTCA
TGAACTTCACAATTCTCAACTATAAGGACTGTGAGAAGGCAGTGAAGAAGTACCACATCGATGGGGCTCGCTTCTTGAACCTGACAGAAA
ATGACATCCAGAAGTTCCCCAAGCTCCGGGTGCCGATTCTCAGTAAGTTAAGTCAGGAAATCAACAAGAACGAAGAGAGGAGGAGCATCT
TCACACGCAAACCCCAAGTCCCGCGGTTTCCTGAAGAGACAGAAAGCCACGAAGAGGACAATGGGGGCTGGTCGTCCTTTGAAGAAGACG
ATTATGAAAGTCCCAATGATGACCAGGATGGGGAGGATGATGGAGACTATGAGTCCCCCAATGAGGAGGAAGAGGCACCCGTGGAAGATG
ACGCGGATTATGAGCCGCCACCCTCCAATGACGAGGAAGCTCTGCAGAACTCCATCCTGCCTGCCAAGCCTTTCCCCAACTCCAACTCCA
TGTACATCGACCGGCCCCCCTCTGGGAAAACCCCCCAGCAGCCTCCTGTGCCCCCCCAGAGACCGATGGCCGCCCTCCCGCCCCCACCAG
CCGGCCGGAATCACTCGCCACTGCCCCCACCCCAGACCAACCACGAAGAACCCAGCAGAAGCAGAAACCACAAAACGGCAAAGCTCCCTG
CTCCTTCAATAGACAGAAGCACGAAACCTCCCCTAGATCGTTCATTAGCTCCGTTTGATAGAGAACCCTTCACACTAGGAAAGAAACCAC
CATTTTCTGACAAGCCCTCGATTCCAGCGGGAAGGTCACTCGGGGAGCATTTACCCAAGATTCAAAAGCCTCCTTTACCACCGACCACGG
AAAGACATGAAAGGAGCAGCCCCCTGCCAGGGAAGAAGCCACCTGTGCCAAAGCATGGATGGGGACCAGACAGAAGAGAGAATGATGAAG
ATGATGTGCATCAGAGACCTTTGCCCCAGCCAGCACTACTTCCTATGAGCTCCAACACTTTCCCTTCAAGATCTACTAAGCCAAGTCCCA
TGAACCCTCTCCCATCCTCTCACATGCCTGGAGCATTCTCAGAAAGTAACAGCAGTTTTCCACAGAGTGCCTCCCTGCCACCATACTTCT
CTCAAGGCCCTAGCAACAGACCACCTATCAGAGCCGAAGGCAGAAACTTCCCCTTGCCACTTCCAAACAAACCTCGGCCCCCATCCCCCG
CGGAGGAAGAGAATTCATTAAATGAAGAGTGGTACGTTTCTTATATTACCCGACCAGAGGCAGAAGCTGCTCTTAGAAAGATAAACCAGG
ATGGCACATTTCTGGTCAGAGACAGCTCTAAAAAAACAACAACCAATCCATATGTCCTCATGGTGTTGTACAAAGATAAAGTTTACAACA
TCCAGATCCGTTATCAGAAGGAAAGTCAAGTTTACTTGTTGGGAACTGGACTCCGAGGGAAAGAGGACTTTCTGTCTGTGTCAGATATTA
TTGACTACTTCAGGAAAATGCCACTTCTGCTCATTGATGGGAAAAACCGAGGTTCCAGATACCAGTGCACATTAACGCATGCTGCAGGGT
ACCCATAGCAAGTTATAGCCGAGCAAATGAACCGTCCTCCTGCCTCTGTTGCCAACACGAGATCAATCAGCCTTGGTCAATGGACAAACA
CTTAGGACTGAACTGAACCCCTCCCCATGAACACAAGGGTTTTATCCTTTCCTTTAAAAACAGTGTTTGAAATGAAGACTGTCAACTATC
CCATAATTTATTTATTCTTCTTCAATGTTTGTAAAGTGCATGAGTCATGTTCACACTTGAAGTCTAGTAGTGCACTGTAATAATTCATTT
TTTAAAAGATTATTTAATGCCCATTTCAAAATACAGTAGTTTACACAGCTACAGAAACAATTTGGGGCAAGTTTTAAAACACTGAAACAG
TAATAGTTATTGGTGTCACATAAAACTGATTTGTTTTTTACAGCCAAACCTCTGTCAGTCAGAGGCATTCATTAGTTTTATACATGTAAT
TTGAAAATCACTAAACCTCGTTTTCTCAGCAGCAATAATTTAAGAGGCTTCAAAAATATAATTTCACTCTTATTTAGTATTTTTTCCTGG
GGGCATTTTTACGTAATTTTTTTATGAAAAGACAAATGCATGTTGAGATAACTTCTGGGATTAAAATAGTCTTTTGCTTTACTTTTTTGG
TTTCCTAAAACAACTTTATTGACTTTTAGTCCATACTGTTATATTTTTGTCTTAAAGAAAATTTAAACTACAAATACCAAAAGAAAACAT
TTTAAATTTAGGGATGAGACTTTGGTGTATCGTGGGTCTAGGTTTAATGAACACATCTGGGGTTAAGTTGGCATTTCTTCACATCTCCAC
ACCCACACCAACCATCACAGCCCCCCACCAACCTTCTCCCAACCCCAAAAGCATTGTCCAGGGATATAGATTTTACCAAAGGCTTCCTGG
GAAGACGAGGGAGCAACACTTTAGATTAAATGTGATCAGACTTTCCTATTAGATATGGCTCTTCTGTCTCTTGTTATCCCCCTGACAGCT
CTGCCATAAAGTCCCTTCTCCTCATCCTTCCCAAACAGGCTGTATAAGTGCTTTGAGGTAATTAAACTCTTTCCTCCAGTTTACAAATAT
CACTTAACAAAAAATATAGGCATTCAGCCAGATTAAAAAACTGGTATTCAGCCAAATAGTGACAATCAGTTGTTCTTCAAGTTTTTCCCT
TTGGGACCTTGGTTGTTATTGCACAACTTTTATTAGCAACAATTTTTGGCGTCTCTGCTTAATCTACAAGTTTTCGAAATGGAAAAGAGT
ATCTTGCAGCTTCATTTTCATGAGCTAATAAAAGGGGTATTGGAAGGAATCTAAGAAGTCACCATTTTAAAACTGATGATATGTTAAAAT
AAGGAGTATGCAGAAGGTAGAGACTTTTAACTGATGATAAAAATGGTGTTTCACAAAATCTCATCCTTAACAACCAGAAGTTCTCAGTTT
AGGGTCCAAAACTTGGGAGTTTAAGGCTGAAAACCCTGCATTCATTTACACGTCTACACAACGGGCTATTCAGCAAGTATTTACTTAGTG
GCTCTTCTGTGTTAAACAAGTGAGCTAGGTACAAGGTAGTAAGGATAGCATACACCATAGGTTCTAGTATCGAGTAAGCTCCACTTGTCT
TGCTTTGCCGTATTCTATCTTTACAATTCAAAAATATCTAAAATGAAGGACCTGATAGATTTCAAAGCAACTATTTGGTAGCGAATCATG
TTTATAAAACAAACCAAAGCTCATTTTAAGTCTATTAGTGGAAAGTGCCATCAGGATTAAGATGTTCTGTTCCATGGCTATGACTGAAAT
CAATGTTGGGAAGCTAATGTTTTCATGACTAGCATTCTCTCTCTGTTCAAGCACCGACAACTCCTTTTGGCTGGGCCTTGCCTCTTTTGG
CCACAGACCTTCTATATGACCCCAGGTGCATCAGTCACAGTTGCTCAGAACCCTGCTCAGTGATAAACATCTTACTAAAGCTGGGTCAAT
CAGGGTCACTCTCTGGAATGTTAAACATGAAGCCTGAGACAAGATCTCTCTTTTATCTGGGGTCCCCAAAGGCAATGCTGTACACTTGGA
GCTGCCTGCTGCCCTGCAACTACTCCCATTTACCAATTATCTGGAAGAACCAGTCTACAATAGAAGACAACGAGGCCAACACACAAAAAC
ACAGTAAAAGTATGGACAAATTAGTGGGATCCCTGAAATCTATTCCAACTATGTGCTTCCAAGTCACATGACTCAATAAATGCTTCAGCT
GGTTGAGTTGTGCTTGGCGTTCACTACCAGGAGAGTTCTGATTAATAAAAACTCATTCCATCAATTAATAATTTAGTAGCTCTCTTTCAA
CCTGAGCCAAATTCAAGCATAAGCTAAAGGATAAGCAGTGACCCATGGCCAATTTCCTATGTCATACACTTGCCATTAGTGACGTAAGTT

>81250_81250_4_SGCD-LCP2_SGCD_chr5_155771687_ENST00000517913_LCP2_chr5_169720376_ENST00000046794_length(amino acids)=571AA_BP=64
MMPQEQYTHHRSTMPGSVGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTILNYKDCEKAVKKYHIDGARFLNLTEN
DIQKFPKLRVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDD
ADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPA
PSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDED
DVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPA
EEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDII

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SGCD-LCP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SGCD-LCP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SGCD-LCP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource