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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SGCD-SYNPO (FusionGDB2 ID:81255)

Fusion Gene Summary for SGCD-SYNPO

check button Fusion gene summary
Fusion gene informationFusion gene name: SGCD-SYNPO
Fusion gene ID: 81255
HgeneTgene
Gene symbol

SGCD

SYNPO

Gene ID

6444

11346

Gene namesarcoglycan deltasynaptopodin
Synonyms35DAG|CMD1L|DAGD|LGMDR6|SG-delta|SGCDP|SGD-
Cytomap

5q33.2-q33.3

5q33.1

Type of geneprotein-codingprotein-coding
Descriptiondelta-sarcoglycan35 kDa dystrophin-associated glycoproteindelta-SGdystrophin associated glycoprotein, delta sarcoglycanplacental delta sarcoglycansarcoglycan, delta (35kDa dystrophin-associated glycoprotein)synaptopodin
Modification date2020032820200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000337851, ENST00000435422, 
ENST00000447401, ENST00000517913, 
ENST00000307662, ENST00000519664, 
ENST00000518872, ENST00000522122, 
ENST00000394243, 
Fusion gene scores* DoF score12 X 10 X 6=7204 X 4 X 3=48
# samples 134
** MAII scorelog2(13/720*10)=-2.46948528330122
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SGCD [Title/Abstract] AND SYNPO [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSGCD(156022061)-SYNPO(150027506), # samples:1
Anticipated loss of major functional domain due to fusion event.SGCD-SYNPO seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSYNPO

GO:0098886

modification of dendritic spine

25164660


check buttonFusion gene breakpoints across SGCD (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SYNPO (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-27-1830-01ASGCDchr5

156022061

+SYNPOchr5

150027506

+


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Fusion Gene ORF analysis for SGCD-SYNPO

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000337851ENST00000307662SGCDchr5

156022061

+SYNPOchr5

150027506

+
5CDS-5UTRENST00000337851ENST00000519664SGCDchr5

156022061

+SYNPOchr5

150027506

+
5CDS-5UTRENST00000435422ENST00000307662SGCDchr5

156022061

+SYNPOchr5

150027506

+
5CDS-5UTRENST00000435422ENST00000519664SGCDchr5

156022061

+SYNPOchr5

150027506

+
5CDS-5UTRENST00000447401ENST00000307662SGCDchr5

156022061

+SYNPOchr5

150027506

+
5CDS-5UTRENST00000447401ENST00000519664SGCDchr5

156022061

+SYNPOchr5

150027506

+
5CDS-5UTRENST00000517913ENST00000307662SGCDchr5

156022061

+SYNPOchr5

150027506

+
5CDS-5UTRENST00000517913ENST00000519664SGCDchr5

156022061

+SYNPOchr5

150027506

+
5CDS-intronENST00000337851ENST00000518872SGCDchr5

156022061

+SYNPOchr5

150027506

+
5CDS-intronENST00000435422ENST00000518872SGCDchr5

156022061

+SYNPOchr5

150027506

+
5CDS-intronENST00000447401ENST00000518872SGCDchr5

156022061

+SYNPOchr5

150027506

+
5CDS-intronENST00000517913ENST00000518872SGCDchr5

156022061

+SYNPOchr5

150027506

+
Frame-shiftENST00000337851ENST00000522122SGCDchr5

156022061

+SYNPOchr5

150027506

+
Frame-shiftENST00000435422ENST00000522122SGCDchr5

156022061

+SYNPOchr5

150027506

+
Frame-shiftENST00000447401ENST00000522122SGCDchr5

156022061

+SYNPOchr5

150027506

+
Frame-shiftENST00000517913ENST00000522122SGCDchr5

156022061

+SYNPOchr5

150027506

+
In-frameENST00000337851ENST00000394243SGCDchr5

156022061

+SYNPOchr5

150027506

+
In-frameENST00000435422ENST00000394243SGCDchr5

156022061

+SYNPOchr5

150027506

+
In-frameENST00000447401ENST00000394243SGCDchr5

156022061

+SYNPOchr5

150027506

+
In-frameENST00000517913ENST00000394243SGCDchr5

156022061

+SYNPOchr5

150027506

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000517913SGCDchr5156022061+ENST00000394243SYNPOchr5150027506+71538643623253963
ENST00000435422SGCDchr5156022061+ENST00000394243SYNPOchr5150027506+727598635233751007
ENST00000447401SGCDchr5156022061+ENST00000394243SYNPOchr5150027506+731010215193410963
ENST00000337851SGCDchr5156022061+ENST00000394243SYNPOchr5150027506+731010215193410963

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000517913ENST00000394243SGCDchr5156022061+SYNPOchr5150027506+0.0012486890.9987513
ENST00000435422ENST00000394243SGCDchr5156022061+SYNPOchr5150027506+0.001525020.998475
ENST00000447401ENST00000394243SGCDchr5156022061+SYNPOchr5150027506+0.001723250.9982767
ENST00000337851ENST00000394243SGCDchr5156022061+SYNPOchr5150027506+0.001723250.9982767

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Fusion Genomic Features for SGCD-SYNPO


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SGCDchr5156022061+SYNPOchr5150027505+6.26E-091
SGCDchr5156022061+SYNPOchr5150027505+6.26E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SGCD-SYNPO


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:156022061/chr5:150027506)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSGCDchr5:156022061chr5:150027506ENST00000337851+691_35167291.0Topological domainCytoplasmic
HgeneSGCDchr5:156022061chr5:150027506ENST00000435422+581_35166290.0Topological domainCytoplasmic
HgeneSGCDchr5:156022061chr5:150027506ENST00000447401+681_35167257.0Topological domainCytoplasmic
HgeneSGCDchr5:156022061chr5:150027506ENST00000517913+8101_35167257.0Topological domainCytoplasmic
HgeneSGCDchr5:156022061chr5:150027506ENST00000337851+6936_56167291.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneSGCDchr5:156022061chr5:150027506ENST00000435422+5836_56166290.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneSGCDchr5:156022061chr5:150027506ENST00000447401+6836_56167257.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneSGCDchr5:156022061chr5:150027506ENST00000517913+81036_56167257.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneSYNPOchr5:156022061chr5:150027506ENST0000030766203753_9080904.0Compositional biasNote=Pro-rich
TgeneSYNPOchr5:156022061chr5:150027506ENST0000039424313753_908133930.0Compositional biasNote=Pro-rich
TgeneSYNPOchr5:156022061chr5:150027506ENST0000051966402753_9080686.0Compositional biasNote=Pro-rich
TgeneSYNPOchr5:156022061chr5:150027506ENST0000052212213753_908133930.0Compositional biasNote=Pro-rich
TgeneSYNPOchr5:156022061chr5:150027506ENST0000030766203562_5650904.0MotifNote=PPxY motif
TgeneSYNPOchr5:156022061chr5:150027506ENST0000030766203581_5840904.0MotifNote=PPxY motif
TgeneSYNPOchr5:156022061chr5:150027506ENST0000039424313562_565133930.0MotifNote=PPxY motif
TgeneSYNPOchr5:156022061chr5:150027506ENST0000039424313581_584133930.0MotifNote=PPxY motif
TgeneSYNPOchr5:156022061chr5:150027506ENST0000051966402562_5650686.0MotifNote=PPxY motif
TgeneSYNPOchr5:156022061chr5:150027506ENST0000051966402581_5840686.0MotifNote=PPxY motif
TgeneSYNPOchr5:156022061chr5:150027506ENST0000052212213562_565133930.0MotifNote=PPxY motif
TgeneSYNPOchr5:156022061chr5:150027506ENST0000052212213581_584133930.0MotifNote=PPxY motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSGCDchr5:156022061chr5:150027506ENST00000337851+6957_289167291.0Topological domainExtracellular
HgeneSGCDchr5:156022061chr5:150027506ENST00000435422+5857_289166290.0Topological domainExtracellular
HgeneSGCDchr5:156022061chr5:150027506ENST00000447401+6857_289167257.0Topological domainExtracellular
HgeneSGCDchr5:156022061chr5:150027506ENST00000517913+81057_289167257.0Topological domainExtracellular


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Fusion Gene Sequence for SGCD-SYNPO


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>81255_81255_1_SGCD-SYNPO_SGCD_chr5_156022061_ENST00000337851_SYNPO_chr5_150027506_ENST00000394243_length(transcript)=7310nt_BP=1021nt
AGAGAGGACTTATCTCCAGCATCTAGCACTACAGAGCAGAGGCTGTGTGGAGAATGGCTGAAAAATCAGAATTGGTTGTAGAAGCAGTTT
TCTTTCTGGTTGTGAGTATGAGCCCGGCAGACACCATGAGCGCTGTTGCAGGGGAGTCGGCCTGTGCTTGACACATGTGTTTCCCATTGA
TAGCTGGAGACAGCCCAGTAGCTGTGAGTCGGTCTGACAAAGCCATATTGAAGTACGGAGTACGGTTTCAAAGCAGTCAGAAAAAGAACG
GGAATGCTGTTCAGGAAATTCTTCAGGCATGGGCAGGGACTTGGCTGCAGTTCTGCAGTTGGAAAATCTGACTGGGGCAGCTTCTGAGCG
CAGGCTGGGCCTGCACACACTCAGCGGGCCGAGTGGCCACCTCCTTCAGAGCTGCTCAGCACGCCCTGGGATCGCGGGCGGTTTTCATCG
GCCGGTTTGTGAAACGGACAAGAGAGAGACATTACTGCCGGGAGTGTTGAGTGAAGGGACCAGGTGGAGATGATGCCTCAGGAGCAGTAC
ACTCACCACCGGAGCACCATGCCTGGCTCTGTGGGGCCACAGGTATACAAGGTGGGGATTTATGGCTGGCGGAAACGATGCCTGTATTTC
TTTGTCCTGCTCCTCATGATTTTAATACTGGTGAACTTGGCCATGACCATCTGGATTCTCAAAGTCATGAACTTCACAATTGATGGAATG
GGAAACCTGAGGATCACAGAAAAAGGTCTAAAGCTAGAAGGAGACTCTGAATTCTTACAACCTCTCTACGCCAAAGAAATCCAGTCCCGA
CCAGGTAATGCCCTGTACTTCAAGTCTGCCAGAAATGTTACAGTGAACATTCTCAATGACCAGACTAAAGTGCTAACTCAGCTTATAACA
GGTCCAAAAGCCGTAGAAGCTTATGGTAAAAAATTTGAGGTAAAAACTGTTTCTGGAAAATTGCTCTTCTCTGCAGACAATAATGAAGTG
GTAGTAGGAGCTGAAAGATTACGAGTTTTAGCGTTGGGCCGGAGCACTAGCCTCACGGAGAAGGATCTGAAAGAAGCCAAGGCGCGGAGC
CAGCAGATTGCAGCCCAGCTGACCACCCCTCCCAGCTCCAATTCCCGTGGCGTCCAGCTCTTCAACAGGCGCCGGCAGAGGGTGAACGAG
TTCACCTTGGAGAGCCACGGCCAGAGGGGACAGAAGCCCAGCCAGGAGTCCCTCAGAGTGCTCCCTTCAAGCCTCCCAGGCCATGCACCG
GGGCTCAGCCTGAGTTCCACCTCGCTGCCGGAGCCAGGCCCTCCACGGCACCCCAGTCCCCAGAGCCCCGACAGAGGGGTCCCTGGCCAC
AGCATGGAGGGGTACTCAGAGGAGGCTAGCTTGCTGCGGCACCTGGAGAAGGTGGCCAGTGAGGAGGAAGAGGTACCACTGGTGGTTTAT
CTAAAGGAGAATGCAGCACTGCTGACAGCCAATGGGCTGCACCTGTCCCAAAACCGAGAGGCCCAGCAGTCCTCACCGGCCCCACCTCCA
GCTGAGGTCCACAGCCCAGCTGCAGATGTCAACCAAAACCTTGCCTCGCCCAGTGCCACGCTCACCACACCAACTTCTAACAGCAGCCAC
AATCCGCCAGCCACCGATGTCAATCAGAACCCACCGGCAACTGTTGTCCCACAGAGCCTGCCACTTTCTAGCATCCAACAGAATTCCTCA
GAGGCCCAACTCCCATCTAATGGCACAGGGCCTGCTTCCAAACCCAGCACCCTGTGTGCTGATGGGCAACCCCAGGCACCGGCTGAGGAG
GTGAGATGCAGCACACTCCTAATTGACAAGGTATCAACTCCAGCTACCACCACCAGCACCTTCTCCAGAGAAGCTACGCTCATCCCCAGC
TCCAGGCCCCCAGCCTCAGATTTCATGTCCAGCTCCCTGCTCATTGACATCCAGCCCAACACCCTAGTGGTGTCAGCAGATCAAGAGATG
TCTGGGCGAGCAGCTGCCACCACGCCCACCAAGGTCTACAGTGAGGTCCACTTCACACTGGCCAAGCCCCCATCAGTGGTCAACAGGACG
GCCAGGCCTTTTGGGATCCAGGCGCCAGGGGGCACCAGCCAGATGGAGAGGAGCCCCATGCTAGAGAGACGACATTTTGGGGAGAAGGCC
CCGGCTCCCCAGCCCCCCAGTTTGCCAGACAGGAGCCCCCGGCCACAGAGACACATAATGTCCCGCAGCCCCATGGTGGAAAGGAGGATG
ATGGGGCAGCGAAGCCCGGCCTCAGAGAGACGCCCCTTGGGGAACTTCACTGCACCCCCCACCTACACTGAGACCTTGTCCACAGCCCCT
CTGGCTTCCTGGGTGAGGTCTCCTCCCTCATATTCTGTCCTGTATCCCAGCTCCGACCCCAAGTCTTCTCATCTGAAGGGCCAGGCGGTT
CCTGCCAGCAAGACGGGCATTCTGGAGGAGTCGATGGCCCGCCGGGGCAGCCGCAAATCCATGTTTACTTTCGTGGAGAAGCCCAAGGTG
ACCCCGAATCCAGACTTGCTGGATCTGGTACAGACAGCGGATGAGAAGCGGCGGCAGAGGGACCAGGGGGAGGTAGGCGTGGAGGAGGAG
CCCTTCGCACTGGGGGCCGAGGCCTCCAACTTCCAGCAGGAGCCAGCACCTCGTGACAGGGCCAGCCCCGCGGCGGCGGAGGAGGTGGTA
CCAGAGTGGGCCTCCTGCCTCAAGTCACCCCGCATCCAGGCCAAGCCGAAGCCCAAACCCAACCAGAACCTCTCCGAGGCCTCTGGGAAG
GGAGCTGAGCTCTACGCCCGCCGCCAGTCACGGATGGAGAAATATGTCATCGAGTCTTCAAGCCACACGCCAGAGCTGGCCCGCTGCCCA
TCACCTACCATGTCCCTGCCTTCCTCCTGGAAATACCCCACTAACGCCCCCGGGGCCTTCCGAGTGGCATCCCGAAGCCCAGCCCGGACC
CCGCCTGCCTCCCTCTACCATGGCTACCTGCCTGAGAACGGGGTCCTGCGCCCAGAGCCCACCAAGCAGCCGCCATACCAGCTGCGCCCC
TCGCTCTTTGTCCTCTCACCTATCAAGGAGCCTGCCAAGGTCTCACCAAGAGCTGCCTCGCCCGCCAAGCCCAGCTCCTTGGACCTGGTG
CCCAACCTGCCCAAGGGGGCTCTCCCTCCATCTCCTGCCCTGCCTCGGCCCTCGCGCTCCTCACCGGGCCTCTACACCTCCCCCGGCCAG
GACAGCCTGCAGCCCACTGCCGTGAGCCCTCCTTACGGCGGTGACATCTCCCCCGTGTCTCCCTCCAGGGCGTGGTCTCCCCGAGCCAAG
CAGGCCCCCAGGCCCTCCTTCTCTACCCGGAACGCCGGGATCGAGGCTCAGGTGTGGAAGCCTTCCTTCTGCTTCAAGTAACGAACCCCA
CGGGGGTCCCACTGCCGGTCAAGTTCCCCTCCTTGAGGGCCAGATGGAGAGCAGATGTGGCAGGAAATGGCACAGAGCTGAGTGAGGAGA
ATGGGGAGTCCATGGTTCAAGGTCAGATGCGGCCACCAGCTGGCTTTGTGACCTTGGGCGAGTCGCCTCCCCTCTCTGAGCTGAAGCCGC
CCCTCCCCTACTACAACAGGGGTCGGACTCCATGTCTGAGCGGGGAGGAGGGTCATGGAGAGAGAACTGTCTGGCAGCCCTGATGCGGTA
GAGGGGCATCCTCTGGCCTTTGTGAGCTGTAGGGATGCAGAGTCTGATGCCAGCGTCTTGCTGGGGGAGTGGCCTAGAAGGGGATCCTAA
CAGGGACTTCTGGAGCAGACAGAGCCTGCCAGTGCCTGTGGAGTCAGCCAGCCGAGGGTCTGCCTCCTCAGCTGCCCCAGGGGGGCCTCC
CTCCTGAGGCTCAAGCTCCTGGCGTCTTTCTTCCTGTTGCTGGATTCTCACCTCCATGGGCCTGTCTCTTCTGCCTCTGCCTTCTGGACA
CCGTTTCCTCTCCGCTGCTTCAGAGAGCTTTGCCTCGCCTCCGCCTGCGCTCCCCTCCAGGGTCCTTCTGCTGGCTGCGGACTCGGCCCA
CCACTGCTGTCTGACGCTTTTCTTCCTGCCCCCTCTGAGGCCTGGCTCTGTTTTAGGGAGATCACTGGGCCCAGGCCTCAGCCCCAGTTC
TACCTGGCTTGCTGTCACCGCTCTAGGGGTGGGGGACGTCCCAGGGGATCCCCAGGAGAAGGAGAGCCCTGTAGGGGGCTGTGCAGATGT
GGGTGTGCCACAGGGAGGGTGGCCCCTAGCCATGTATCCATTGGCTGTTTTGGCTTCAGATTCAACCAAGATCTGCCTGACTAAAAGAAG
CCACCTCAGCGCAGTGGAACGGGGCCCAGGGGGAGGCAGGAGAGGAGGGTTCCGGTCCCATGTCACCTTCTCATTTGCTGTGTGACTTTG
GCCCACTCACATTCTCTTTGGGCCTCAGTTTTATCATTTATACAAGGAGGGCTTTTCTAGCTGTAACAATCTGTGAGGATTGAGAGGATA
GGCTGGTGCTTTGAAGAAAGGCCTTGTAAGTGACAAGACAGTCCCCTGGGAAGAAAGAGAAAGGAAATGGGCTATTGCCAAAGGACAGGT
GGCGTTAGATGGCTGTGAGGGTGACCTGGTGAGGGAAGGGTTGGAATGAGCTGCTGCAGGAGGCCAAGGGATGCCTGGGCTGGGCTGGGC
TGGGCTGGCTTAGGCTCAGGATTGCCTGGGGACAGTAGGAGCATGGCAGGAGCTGGGGCAGGTGCATAGCAGTGCAGTGGGAAGGGACAG
AGGAGATCTTAGAATTTTGAGGAAAATCTGGGACTTGAGACCTGGATTCTAACAGACCAACTGCATGTGTGTCTGTAGGTCTCAGTTTCC
ACATTCATACAGTGAGGGTGTTAAGTCAGGTAGCTGGAGACTTCCCATCGCCTCTGACACTTTTGGAGGTGATATGATACAGCCCCCGAC
CAAACCAGGCTTTGTGGGGGGTGAGAGAATACAGACACAAGTGGCAGGATTCAGATGGAAGCTTCGCAAGGCTGGGGGCCGAGGACCACC
CACTTCTCTTTCCCAGCCCTAGTTCTGGGTTCCCCAGTGGGGCAAGGGGTGGTGGAGGCAGTGCCCATGCTGGGCTGAGCCTGCAGTTTT
TGTGAGCTCTGGGCTTGTCTCCATGGGAACAGGGGTGCCTTCTTAGTGAGCTCATTTCACACAGATCGAGGGGGTATGCGTGGGGGAGTT
GTGAGTGAGCTCAGCTCCTTCAGGCCTGGCCTCTCCCAGAACAGAGTGAAGCCCCTGCCCTGGACCCCTGCTCCCTTCTACCCTTGAGGG
CCACCAATGGAAGAGCCCGCCCTTCATTCTGCAGCTCCTGCGGCCAGGCTGAGCTCTGCCCCCAACTTTGTTTTCTCTCATGTTCTCAAT
ACACTCTGCCTCAAATCCGTCTTGCTTCTTTCTTTCTTCCGTGCTGCTAGGGGTCAGGGTTCCCTTCCTCCTGCCTGATTCTAGCCTGGG
AAGTGGAGTGGGCCTGCTCAATTACTGTGTGTGAAAGTGTGGCTGTGTCCTGCGTGCTGCCTGCACCTGCCGTGTGTCTGGTTCTGCACT
GGTACAGACGTGTGCTGGGTTGGAAATGAGGGCTTCCTCTCTACAGCACTCAGGGAGCCAGAACCCTGTGCAAATCGCAACCTTTTGTTC
TTTCCTTCCCTCAGAGTTTGGCCAAAAATACTTTAGAGGATTTTTGGGGAAAATGCACTACCTCTTCTCGTTGAGGTTTGTTTGGGTTCT
TTACAAGTGGAATAGAAATTCCTCTAGCCAGCATTCGCTCTCCAGTTCCCTCAGGTCCCCTCCCTGCTCCCCATTATCTAAATTTGGCCA
TTTCCCACATTTGCCATTGTTTTCACTGTCTGGATCCTAAAAGCATGGAGTTTCTGCCCCTGGTGGGGAGGAAAGAACTGCCATCAAGGG
TCAGGAGAGCTGGGTTCTAGCCCCAGGTCTGCATCTGATTCGTGTGTGACCTCAGACAACCTCTTCCAATCTCTGGGCCTCAGTTTCCCC
TTCTGTGCAGTGAAAGGATTACAGAAGGAGGTCAGAGACCATTTGGTCTCCGACAGTCCAGGTTTGACTGTGTTCTACTTATGTATTCAC
CCCACACATGTGCCCTGCTTTGGGTCTGGGGTTGGGTTGAGTGGATGCTACTTTTTGAATTTTCACCCACCGCATTCCCAAGGAGCTCTG
GTGTGCACGGTGCATTGAGCTCTCTGTCAGAAAGTGAACAGTTCTGATTTCCTGCAGCCTTTTCGTACTGTGCACACCCCCGACTCAAAA
ACATACACACAGAGTCAGTGCCCAGGCATGGCTGTTAGGGTGAGGTCAGGCTCTGGCCCATCTCCAGATGATGGGGATCTGCTTACCACT
GCCCTCAACATTCAATCCCGTTTGAGCCCTTCTGTTTTGTAGTCTTGGCTGAATTGTTATTTCTTCCACTTGTTGGCCTCAGCATTCCCC
TTGTGGCCACCAAAGGCAGAAACAATGCTTTAGAGATTTTTAGGTAGTTATCATAGCTCTCCTGTGCAGCCTACTCTCCTGGCTGAAGAC
CCCAGGTTCCGCTGCCTTGGGTGGTTATTGACTGGCTTGGGTCATGAACTCTAGGCCCTACCTCCCTGCTCAGGGTGGCACTGTGGTCAG
GTGTTGGGTCATGCCAGAGCCCACCCTGATTTGGCATTTGGCCCTAGCCCTCCTCTTCTAGCCCTGGAGCTGGGACCTTCCTCCCAGCTC
CTCTCCCTAAACTGTGGGGTCTGCCTTCTGCGGCCAGCCTGACTGGGATGTTCCACTGGCACAGAGAAGCTCCCAGTGTCTCTGGCTCAT
GTATACACAATTCTGACCCTGGGAAGAAAACAGTGGGATCCCAGGCTGAGCCTTAACTTTCAGCTTGATGACTGGGAGCTTGGATGTCCC
TAGGGAGTCTCTAAGGGTCACTCCAGCATTAGTATCCCATGAAAAATGTCCTGCTCAGGCTGTTGTATAACATTCTTCTTTAGGTTAAAG
GGCTCCAGTTTGGAGTCTGGGCTCATCTAGCAGCTGCTACATTCTGTTTGGATAAAACATACAATTGGTGTCTATTTCCTTTGGATTGGG
AGGAATTAGAAGACTCTCAGTTGGATGAGAGGATGACTGGCTTGGTTATGGCTGATCACTGATTGGATGAAAGAATAAATCTTTGGATGG
TTCTAGATTTTGATCGGGTAGGAAGCATGGAATGGACTGGCTAGCTCTGAACTCTGGTGGATGACTGCTAGTGAATTTGGATTGGATTAA

>81255_81255_1_SGCD-SYNPO_SGCD_chr5_156022061_ENST00000337851_SYNPO_chr5_150027506_ENST00000394243_length(amino acids)=963AA_BP=162
MMPQEQYTHHRSTMPGSVGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLY
AKEIQSRPGNALYFKSARNVTVNILNDQTKVLTQLITGPKAVEAYGKKFEVKTVSGKLLFSADNNEVVVGAERLRVLALGRSTSLTEKDL
KEAKARSQQIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESHGQRGQKPSQESLRVLPSSLPGHAPGLSLSSTSLPEPGPPRHPSPQSP
DRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTT
PTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSR
EATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLER
RHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSS
HLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASP
AAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVA
SRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPG

--------------------------------------------------------------
>81255_81255_2_SGCD-SYNPO_SGCD_chr5_156022061_ENST00000435422_SYNPO_chr5_150027506_ENST00000394243_length(transcript)=7275nt_BP=986nt
GAGCAGAAGAAAGAGAGGACTTATCTCCAGCATCTAGCACTACAGAGCAGAGGCTGTGTGGAGAATGGCTGAAAAATCAGAATTGGTTGT
AGAAGCAGTTTTCTTTCTGGTTGTGAGTATGAGCCCGGCAGACACCATGAGCGCTGTTGCAGGGGAGTCGGCCTGTGCTTGACACATGTG
TTTCCCATTGATAGCTGGAGACAGCCCAGTAGCTGTGAGTCGGTCTGACAAAGCCATATTGAAGTACGGAGTACGGTTTCAAAGCAGTCA
GAAAAAGAACGGGAATGCTGTTCAGGAAATTCTTCAGGCATGGGCAGGGACTTGGCTGCAGTTCTGCAGTTGGAAAATCTGACTGGGGCA
GCTTCTGAGCGCAGGCTGGGCCTGCACACACTCAGCGGGCCGAGTGGCCACCTCCTTCAGAGCTGCTCAGCACGCCCTGGGATCGCGGGC
GGTTTTCATCGGCCGGTTTGTGAAACGGACAAGAGAGATGCCTCAGGAGCAGTACACTCACCACCGGAGCACCATGCCTGGCTCTGTGGG
GCCACAGGTATACAAGGTGGGGATTTATGGCTGGCGGAAACGATGCCTGTATTTCTTTGTCCTGCTCCTCATGATTTTAATACTGGTGAA
CTTGGCCATGACCATCTGGATTCTCAAAGTCATGAACTTCACAATTGATGGAATGGGAAACCTGAGGATCACAGAAAAAGGTCTAAAGCT
AGAAGGAGACTCTGAATTCTTACAACCTCTCTACGCCAAAGAAATCCAGTCCCGACCAGGTAATGCCCTGTACTTCAAGTCTGCCAGAAA
TGTTACAGTGAACATTCTCAATGACCAGACTAAAGTGCTAACTCAGCTTATAACAGGTCCAAAAGCCGTAGAAGCTTATGGTAAAAAATT
TGAGGTAAAAACTGTTTCTGGAAAATTGCTCTTCTCTGCAGACAATAATGAAGTGGTAGTAGGAGCTGAAAGATTACGAGTTTTAGCGTT
GGGCCGGAGCACTAGCCTCACGGAGAAGGATCTGAAAGAAGCCAAGGCGCGGAGCCAGCAGATTGCAGCCCAGCTGACCACCCCTCCCAG
CTCCAATTCCCGTGGCGTCCAGCTCTTCAACAGGCGCCGGCAGAGGGTGAACGAGTTCACCTTGGAGAGCCACGGCCAGAGGGGACAGAA
GCCCAGCCAGGAGTCCCTCAGAGTGCTCCCTTCAAGCCTCCCAGGCCATGCACCGGGGCTCAGCCTGAGTTCCACCTCGCTGCCGGAGCC
AGGCCCTCCACGGCACCCCAGTCCCCAGAGCCCCGACAGAGGGGTCCCTGGCCACAGCATGGAGGGGTACTCAGAGGAGGCTAGCTTGCT
GCGGCACCTGGAGAAGGTGGCCAGTGAGGAGGAAGAGGTACCACTGGTGGTTTATCTAAAGGAGAATGCAGCACTGCTGACAGCCAATGG
GCTGCACCTGTCCCAAAACCGAGAGGCCCAGCAGTCCTCACCGGCCCCACCTCCAGCTGAGGTCCACAGCCCAGCTGCAGATGTCAACCA
AAACCTTGCCTCGCCCAGTGCCACGCTCACCACACCAACTTCTAACAGCAGCCACAATCCGCCAGCCACCGATGTCAATCAGAACCCACC
GGCAACTGTTGTCCCACAGAGCCTGCCACTTTCTAGCATCCAACAGAATTCCTCAGAGGCCCAACTCCCATCTAATGGCACAGGGCCTGC
TTCCAAACCCAGCACCCTGTGTGCTGATGGGCAACCCCAGGCACCGGCTGAGGAGGTGAGATGCAGCACACTCCTAATTGACAAGGTATC
AACTCCAGCTACCACCACCAGCACCTTCTCCAGAGAAGCTACGCTCATCCCCAGCTCCAGGCCCCCAGCCTCAGATTTCATGTCCAGCTC
CCTGCTCATTGACATCCAGCCCAACACCCTAGTGGTGTCAGCAGATCAAGAGATGTCTGGGCGAGCAGCTGCCACCACGCCCACCAAGGT
CTACAGTGAGGTCCACTTCACACTGGCCAAGCCCCCATCAGTGGTCAACAGGACGGCCAGGCCTTTTGGGATCCAGGCGCCAGGGGGCAC
CAGCCAGATGGAGAGGAGCCCCATGCTAGAGAGACGACATTTTGGGGAGAAGGCCCCGGCTCCCCAGCCCCCCAGTTTGCCAGACAGGAG
CCCCCGGCCACAGAGACACATAATGTCCCGCAGCCCCATGGTGGAAAGGAGGATGATGGGGCAGCGAAGCCCGGCCTCAGAGAGACGCCC
CTTGGGGAACTTCACTGCACCCCCCACCTACACTGAGACCTTGTCCACAGCCCCTCTGGCTTCCTGGGTGAGGTCTCCTCCCTCATATTC
TGTCCTGTATCCCAGCTCCGACCCCAAGTCTTCTCATCTGAAGGGCCAGGCGGTTCCTGCCAGCAAGACGGGCATTCTGGAGGAGTCGAT
GGCCCGCCGGGGCAGCCGCAAATCCATGTTTACTTTCGTGGAGAAGCCCAAGGTGACCCCGAATCCAGACTTGCTGGATCTGGTACAGAC
AGCGGATGAGAAGCGGCGGCAGAGGGACCAGGGGGAGGTAGGCGTGGAGGAGGAGCCCTTCGCACTGGGGGCCGAGGCCTCCAACTTCCA
GCAGGAGCCAGCACCTCGTGACAGGGCCAGCCCCGCGGCGGCGGAGGAGGTGGTACCAGAGTGGGCCTCCTGCCTCAAGTCACCCCGCAT
CCAGGCCAAGCCGAAGCCCAAACCCAACCAGAACCTCTCCGAGGCCTCTGGGAAGGGAGCTGAGCTCTACGCCCGCCGCCAGTCACGGAT
GGAGAAATATGTCATCGAGTCTTCAAGCCACACGCCAGAGCTGGCCCGCTGCCCATCACCTACCATGTCCCTGCCTTCCTCCTGGAAATA
CCCCACTAACGCCCCCGGGGCCTTCCGAGTGGCATCCCGAAGCCCAGCCCGGACCCCGCCTGCCTCCCTCTACCATGGCTACCTGCCTGA
GAACGGGGTCCTGCGCCCAGAGCCCACCAAGCAGCCGCCATACCAGCTGCGCCCCTCGCTCTTTGTCCTCTCACCTATCAAGGAGCCTGC
CAAGGTCTCACCAAGAGCTGCCTCGCCCGCCAAGCCCAGCTCCTTGGACCTGGTGCCCAACCTGCCCAAGGGGGCTCTCCCTCCATCTCC
TGCCCTGCCTCGGCCCTCGCGCTCCTCACCGGGCCTCTACACCTCCCCCGGCCAGGACAGCCTGCAGCCCACTGCCGTGAGCCCTCCTTA
CGGCGGTGACATCTCCCCCGTGTCTCCCTCCAGGGCGTGGTCTCCCCGAGCCAAGCAGGCCCCCAGGCCCTCCTTCTCTACCCGGAACGC
CGGGATCGAGGCTCAGGTGTGGAAGCCTTCCTTCTGCTTCAAGTAACGAACCCCACGGGGGTCCCACTGCCGGTCAAGTTCCCCTCCTTG
AGGGCCAGATGGAGAGCAGATGTGGCAGGAAATGGCACAGAGCTGAGTGAGGAGAATGGGGAGTCCATGGTTCAAGGTCAGATGCGGCCA
CCAGCTGGCTTTGTGACCTTGGGCGAGTCGCCTCCCCTCTCTGAGCTGAAGCCGCCCCTCCCCTACTACAACAGGGGTCGGACTCCATGT
CTGAGCGGGGAGGAGGGTCATGGAGAGAGAACTGTCTGGCAGCCCTGATGCGGTAGAGGGGCATCCTCTGGCCTTTGTGAGCTGTAGGGA
TGCAGAGTCTGATGCCAGCGTCTTGCTGGGGGAGTGGCCTAGAAGGGGATCCTAACAGGGACTTCTGGAGCAGACAGAGCCTGCCAGTGC
CTGTGGAGTCAGCCAGCCGAGGGTCTGCCTCCTCAGCTGCCCCAGGGGGGCCTCCCTCCTGAGGCTCAAGCTCCTGGCGTCTTTCTTCCT
GTTGCTGGATTCTCACCTCCATGGGCCTGTCTCTTCTGCCTCTGCCTTCTGGACACCGTTTCCTCTCCGCTGCTTCAGAGAGCTTTGCCT
CGCCTCCGCCTGCGCTCCCCTCCAGGGTCCTTCTGCTGGCTGCGGACTCGGCCCACCACTGCTGTCTGACGCTTTTCTTCCTGCCCCCTC
TGAGGCCTGGCTCTGTTTTAGGGAGATCACTGGGCCCAGGCCTCAGCCCCAGTTCTACCTGGCTTGCTGTCACCGCTCTAGGGGTGGGGG
ACGTCCCAGGGGATCCCCAGGAGAAGGAGAGCCCTGTAGGGGGCTGTGCAGATGTGGGTGTGCCACAGGGAGGGTGGCCCCTAGCCATGT
ATCCATTGGCTGTTTTGGCTTCAGATTCAACCAAGATCTGCCTGACTAAAAGAAGCCACCTCAGCGCAGTGGAACGGGGCCCAGGGGGAG
GCAGGAGAGGAGGGTTCCGGTCCCATGTCACCTTCTCATTTGCTGTGTGACTTTGGCCCACTCACATTCTCTTTGGGCCTCAGTTTTATC
ATTTATACAAGGAGGGCTTTTCTAGCTGTAACAATCTGTGAGGATTGAGAGGATAGGCTGGTGCTTTGAAGAAAGGCCTTGTAAGTGACA
AGACAGTCCCCTGGGAAGAAAGAGAAAGGAAATGGGCTATTGCCAAAGGACAGGTGGCGTTAGATGGCTGTGAGGGTGACCTGGTGAGGG
AAGGGTTGGAATGAGCTGCTGCAGGAGGCCAAGGGATGCCTGGGCTGGGCTGGGCTGGGCTGGCTTAGGCTCAGGATTGCCTGGGGACAG
TAGGAGCATGGCAGGAGCTGGGGCAGGTGCATAGCAGTGCAGTGGGAAGGGACAGAGGAGATCTTAGAATTTTGAGGAAAATCTGGGACT
TGAGACCTGGATTCTAACAGACCAACTGCATGTGTGTCTGTAGGTCTCAGTTTCCACATTCATACAGTGAGGGTGTTAAGTCAGGTAGCT
GGAGACTTCCCATCGCCTCTGACACTTTTGGAGGTGATATGATACAGCCCCCGACCAAACCAGGCTTTGTGGGGGGTGAGAGAATACAGA
CACAAGTGGCAGGATTCAGATGGAAGCTTCGCAAGGCTGGGGGCCGAGGACCACCCACTTCTCTTTCCCAGCCCTAGTTCTGGGTTCCCC
AGTGGGGCAAGGGGTGGTGGAGGCAGTGCCCATGCTGGGCTGAGCCTGCAGTTTTTGTGAGCTCTGGGCTTGTCTCCATGGGAACAGGGG
TGCCTTCTTAGTGAGCTCATTTCACACAGATCGAGGGGGTATGCGTGGGGGAGTTGTGAGTGAGCTCAGCTCCTTCAGGCCTGGCCTCTC
CCAGAACAGAGTGAAGCCCCTGCCCTGGACCCCTGCTCCCTTCTACCCTTGAGGGCCACCAATGGAAGAGCCCGCCCTTCATTCTGCAGC
TCCTGCGGCCAGGCTGAGCTCTGCCCCCAACTTTGTTTTCTCTCATGTTCTCAATACACTCTGCCTCAAATCCGTCTTGCTTCTTTCTTT
CTTCCGTGCTGCTAGGGGTCAGGGTTCCCTTCCTCCTGCCTGATTCTAGCCTGGGAAGTGGAGTGGGCCTGCTCAATTACTGTGTGTGAA
AGTGTGGCTGTGTCCTGCGTGCTGCCTGCACCTGCCGTGTGTCTGGTTCTGCACTGGTACAGACGTGTGCTGGGTTGGAAATGAGGGCTT
CCTCTCTACAGCACTCAGGGAGCCAGAACCCTGTGCAAATCGCAACCTTTTGTTCTTTCCTTCCCTCAGAGTTTGGCCAAAAATACTTTA
GAGGATTTTTGGGGAAAATGCACTACCTCTTCTCGTTGAGGTTTGTTTGGGTTCTTTACAAGTGGAATAGAAATTCCTCTAGCCAGCATT
CGCTCTCCAGTTCCCTCAGGTCCCCTCCCTGCTCCCCATTATCTAAATTTGGCCATTTCCCACATTTGCCATTGTTTTCACTGTCTGGAT
CCTAAAAGCATGGAGTTTCTGCCCCTGGTGGGGAGGAAAGAACTGCCATCAAGGGTCAGGAGAGCTGGGTTCTAGCCCCAGGTCTGCATC
TGATTCGTGTGTGACCTCAGACAACCTCTTCCAATCTCTGGGCCTCAGTTTCCCCTTCTGTGCAGTGAAAGGATTACAGAAGGAGGTCAG
AGACCATTTGGTCTCCGACAGTCCAGGTTTGACTGTGTTCTACTTATGTATTCACCCCACACATGTGCCCTGCTTTGGGTCTGGGGTTGG
GTTGAGTGGATGCTACTTTTTGAATTTTCACCCACCGCATTCCCAAGGAGCTCTGGTGTGCACGGTGCATTGAGCTCTCTGTCAGAAAGT
GAACAGTTCTGATTTCCTGCAGCCTTTTCGTACTGTGCACACCCCCGACTCAAAAACATACACACAGAGTCAGTGCCCAGGCATGGCTGT
TAGGGTGAGGTCAGGCTCTGGCCCATCTCCAGATGATGGGGATCTGCTTACCACTGCCCTCAACATTCAATCCCGTTTGAGCCCTTCTGT
TTTGTAGTCTTGGCTGAATTGTTATTTCTTCCACTTGTTGGCCTCAGCATTCCCCTTGTGGCCACCAAAGGCAGAAACAATGCTTTAGAG
ATTTTTAGGTAGTTATCATAGCTCTCCTGTGCAGCCTACTCTCCTGGCTGAAGACCCCAGGTTCCGCTGCCTTGGGTGGTTATTGACTGG
CTTGGGTCATGAACTCTAGGCCCTACCTCCCTGCTCAGGGTGGCACTGTGGTCAGGTGTTGGGTCATGCCAGAGCCCACCCTGATTTGGC
ATTTGGCCCTAGCCCTCCTCTTCTAGCCCTGGAGCTGGGACCTTCCTCCCAGCTCCTCTCCCTAAACTGTGGGGTCTGCCTTCTGCGGCC
AGCCTGACTGGGATGTTCCACTGGCACAGAGAAGCTCCCAGTGTCTCTGGCTCATGTATACACAATTCTGACCCTGGGAAGAAAACAGTG
GGATCCCAGGCTGAGCCTTAACTTTCAGCTTGATGACTGGGAGCTTGGATGTCCCTAGGGAGTCTCTAAGGGTCACTCCAGCATTAGTAT
CCCATGAAAAATGTCCTGCTCAGGCTGTTGTATAACATTCTTCTTTAGGTTAAAGGGCTCCAGTTTGGAGTCTGGGCTCATCTAGCAGCT
GCTACATTCTGTTTGGATAAAACATACAATTGGTGTCTATTTCCTTTGGATTGGGAGGAATTAGAAGACTCTCAGTTGGATGAGAGGATG
ACTGGCTTGGTTATGGCTGATCACTGATTGGATGAAAGAATAAATCTTTGGATGGTTCTAGATTTTGATCGGGTAGGAAGCATGGAATGG

>81255_81255_2_SGCD-SYNPO_SGCD_chr5_156022061_ENST00000435422_SYNPO_chr5_150027506_ENST00000394243_length(amino acids)=1007AA_BP=206
MGQLLSAGWACTHSAGRVATSFRAAQHALGSRAVFIGRFVKRTREMPQEQYTHHRSTMPGSVGPQVYKVGIYGWRKRCLYFFVLLLMILI
LVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIQSRPGNALYFKSARNVTVNILNDQTKVLTQLITGPKAVEAYG
KKFEVKTVSGKLLFSADNNEVVVGAERLRVLALGRSTSLTEKDLKEAKARSQQIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESHGQR
GQKPSQESLRVLPSSLPGHAPGLSLSSTSLPEPGPPRHPSPQSPDRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLT
ANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGT
GPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTP
TKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASE
RRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDL
VQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQ
SRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIK
EPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFST

--------------------------------------------------------------
>81255_81255_3_SGCD-SYNPO_SGCD_chr5_156022061_ENST00000447401_SYNPO_chr5_150027506_ENST00000394243_length(transcript)=7310nt_BP=1021nt
AGAGAGGACTTATCTCCAGCATCTAGCACTACAGAGCAGAGGCTGTGTGGAGAATGGCTGAAAAATCAGAATTGGTTGTAGAAGCAGTTT
TCTTTCTGGTTGTGAGTATGAGCCCGGCAGACACCATGAGCGCTGTTGCAGGGGAGTCGGCCTGTGCTTGACACATGTGTTTCCCATTGA
TAGCTGGAGACAGCCCAGTAGCTGTGAGTCGGTCTGACAAAGCCATATTGAAGTACGGAGTACGGTTTCAAAGCAGTCAGAAAAAGAACG
GGAATGCTGTTCAGGAAATTCTTCAGGCATGGGCAGGGACTTGGCTGCAGTTCTGCAGTTGGAAAATCTGACTGGGGCAGCTTCTGAGCG
CAGGCTGGGCCTGCACACACTCAGCGGGCCGAGTGGCCACCTCCTTCAGAGCTGCTCAGCACGCCCTGGGATCGCGGGCGGTTTTCATCG
GCCGGTTTGTGAAACGGACAAGAGAGAGACATTACTGCCGGGAGTGTTGAGTGAAGGGACCAGGTGGAGATGATGCCTCAGGAGCAGTAC
ACTCACCACCGGAGCACCATGCCTGGCTCTGTGGGGCCACAGGTATACAAGGTGGGGATTTATGGCTGGCGGAAACGATGCCTGTATTTC
TTTGTCCTGCTCCTCATGATTTTAATACTGGTGAACTTGGCCATGACCATCTGGATTCTCAAAGTCATGAACTTCACAATTGATGGAATG
GGAAACCTGAGGATCACAGAAAAAGGTCTAAAGCTAGAAGGAGACTCTGAATTCTTACAACCTCTCTACGCCAAAGAAATCCAGTCCCGA
CCAGGTAATGCCCTGTACTTCAAGTCTGCCAGAAATGTTACAGTGAACATTCTCAATGACCAGACTAAAGTGCTAACTCAGCTTATAACA
GGTCCAAAAGCCGTAGAAGCTTATGGTAAAAAATTTGAGGTAAAAACTGTTTCTGGAAAATTGCTCTTCTCTGCAGACAATAATGAAGTG
GTAGTAGGAGCTGAAAGATTACGAGTTTTAGCGTTGGGCCGGAGCACTAGCCTCACGGAGAAGGATCTGAAAGAAGCCAAGGCGCGGAGC
CAGCAGATTGCAGCCCAGCTGACCACCCCTCCCAGCTCCAATTCCCGTGGCGTCCAGCTCTTCAACAGGCGCCGGCAGAGGGTGAACGAG
TTCACCTTGGAGAGCCACGGCCAGAGGGGACAGAAGCCCAGCCAGGAGTCCCTCAGAGTGCTCCCTTCAAGCCTCCCAGGCCATGCACCG
GGGCTCAGCCTGAGTTCCACCTCGCTGCCGGAGCCAGGCCCTCCACGGCACCCCAGTCCCCAGAGCCCCGACAGAGGGGTCCCTGGCCAC
AGCATGGAGGGGTACTCAGAGGAGGCTAGCTTGCTGCGGCACCTGGAGAAGGTGGCCAGTGAGGAGGAAGAGGTACCACTGGTGGTTTAT
CTAAAGGAGAATGCAGCACTGCTGACAGCCAATGGGCTGCACCTGTCCCAAAACCGAGAGGCCCAGCAGTCCTCACCGGCCCCACCTCCA
GCTGAGGTCCACAGCCCAGCTGCAGATGTCAACCAAAACCTTGCCTCGCCCAGTGCCACGCTCACCACACCAACTTCTAACAGCAGCCAC
AATCCGCCAGCCACCGATGTCAATCAGAACCCACCGGCAACTGTTGTCCCACAGAGCCTGCCACTTTCTAGCATCCAACAGAATTCCTCA
GAGGCCCAACTCCCATCTAATGGCACAGGGCCTGCTTCCAAACCCAGCACCCTGTGTGCTGATGGGCAACCCCAGGCACCGGCTGAGGAG
GTGAGATGCAGCACACTCCTAATTGACAAGGTATCAACTCCAGCTACCACCACCAGCACCTTCTCCAGAGAAGCTACGCTCATCCCCAGC
TCCAGGCCCCCAGCCTCAGATTTCATGTCCAGCTCCCTGCTCATTGACATCCAGCCCAACACCCTAGTGGTGTCAGCAGATCAAGAGATG
TCTGGGCGAGCAGCTGCCACCACGCCCACCAAGGTCTACAGTGAGGTCCACTTCACACTGGCCAAGCCCCCATCAGTGGTCAACAGGACG
GCCAGGCCTTTTGGGATCCAGGCGCCAGGGGGCACCAGCCAGATGGAGAGGAGCCCCATGCTAGAGAGACGACATTTTGGGGAGAAGGCC
CCGGCTCCCCAGCCCCCCAGTTTGCCAGACAGGAGCCCCCGGCCACAGAGACACATAATGTCCCGCAGCCCCATGGTGGAAAGGAGGATG
ATGGGGCAGCGAAGCCCGGCCTCAGAGAGACGCCCCTTGGGGAACTTCACTGCACCCCCCACCTACACTGAGACCTTGTCCACAGCCCCT
CTGGCTTCCTGGGTGAGGTCTCCTCCCTCATATTCTGTCCTGTATCCCAGCTCCGACCCCAAGTCTTCTCATCTGAAGGGCCAGGCGGTT
CCTGCCAGCAAGACGGGCATTCTGGAGGAGTCGATGGCCCGCCGGGGCAGCCGCAAATCCATGTTTACTTTCGTGGAGAAGCCCAAGGTG
ACCCCGAATCCAGACTTGCTGGATCTGGTACAGACAGCGGATGAGAAGCGGCGGCAGAGGGACCAGGGGGAGGTAGGCGTGGAGGAGGAG
CCCTTCGCACTGGGGGCCGAGGCCTCCAACTTCCAGCAGGAGCCAGCACCTCGTGACAGGGCCAGCCCCGCGGCGGCGGAGGAGGTGGTA
CCAGAGTGGGCCTCCTGCCTCAAGTCACCCCGCATCCAGGCCAAGCCGAAGCCCAAACCCAACCAGAACCTCTCCGAGGCCTCTGGGAAG
GGAGCTGAGCTCTACGCCCGCCGCCAGTCACGGATGGAGAAATATGTCATCGAGTCTTCAAGCCACACGCCAGAGCTGGCCCGCTGCCCA
TCACCTACCATGTCCCTGCCTTCCTCCTGGAAATACCCCACTAACGCCCCCGGGGCCTTCCGAGTGGCATCCCGAAGCCCAGCCCGGACC
CCGCCTGCCTCCCTCTACCATGGCTACCTGCCTGAGAACGGGGTCCTGCGCCCAGAGCCCACCAAGCAGCCGCCATACCAGCTGCGCCCC
TCGCTCTTTGTCCTCTCACCTATCAAGGAGCCTGCCAAGGTCTCACCAAGAGCTGCCTCGCCCGCCAAGCCCAGCTCCTTGGACCTGGTG
CCCAACCTGCCCAAGGGGGCTCTCCCTCCATCTCCTGCCCTGCCTCGGCCCTCGCGCTCCTCACCGGGCCTCTACACCTCCCCCGGCCAG
GACAGCCTGCAGCCCACTGCCGTGAGCCCTCCTTACGGCGGTGACATCTCCCCCGTGTCTCCCTCCAGGGCGTGGTCTCCCCGAGCCAAG
CAGGCCCCCAGGCCCTCCTTCTCTACCCGGAACGCCGGGATCGAGGCTCAGGTGTGGAAGCCTTCCTTCTGCTTCAAGTAACGAACCCCA
CGGGGGTCCCACTGCCGGTCAAGTTCCCCTCCTTGAGGGCCAGATGGAGAGCAGATGTGGCAGGAAATGGCACAGAGCTGAGTGAGGAGA
ATGGGGAGTCCATGGTTCAAGGTCAGATGCGGCCACCAGCTGGCTTTGTGACCTTGGGCGAGTCGCCTCCCCTCTCTGAGCTGAAGCCGC
CCCTCCCCTACTACAACAGGGGTCGGACTCCATGTCTGAGCGGGGAGGAGGGTCATGGAGAGAGAACTGTCTGGCAGCCCTGATGCGGTA
GAGGGGCATCCTCTGGCCTTTGTGAGCTGTAGGGATGCAGAGTCTGATGCCAGCGTCTTGCTGGGGGAGTGGCCTAGAAGGGGATCCTAA
CAGGGACTTCTGGAGCAGACAGAGCCTGCCAGTGCCTGTGGAGTCAGCCAGCCGAGGGTCTGCCTCCTCAGCTGCCCCAGGGGGGCCTCC
CTCCTGAGGCTCAAGCTCCTGGCGTCTTTCTTCCTGTTGCTGGATTCTCACCTCCATGGGCCTGTCTCTTCTGCCTCTGCCTTCTGGACA
CCGTTTCCTCTCCGCTGCTTCAGAGAGCTTTGCCTCGCCTCCGCCTGCGCTCCCCTCCAGGGTCCTTCTGCTGGCTGCGGACTCGGCCCA
CCACTGCTGTCTGACGCTTTTCTTCCTGCCCCCTCTGAGGCCTGGCTCTGTTTTAGGGAGATCACTGGGCCCAGGCCTCAGCCCCAGTTC
TACCTGGCTTGCTGTCACCGCTCTAGGGGTGGGGGACGTCCCAGGGGATCCCCAGGAGAAGGAGAGCCCTGTAGGGGGCTGTGCAGATGT
GGGTGTGCCACAGGGAGGGTGGCCCCTAGCCATGTATCCATTGGCTGTTTTGGCTTCAGATTCAACCAAGATCTGCCTGACTAAAAGAAG
CCACCTCAGCGCAGTGGAACGGGGCCCAGGGGGAGGCAGGAGAGGAGGGTTCCGGTCCCATGTCACCTTCTCATTTGCTGTGTGACTTTG
GCCCACTCACATTCTCTTTGGGCCTCAGTTTTATCATTTATACAAGGAGGGCTTTTCTAGCTGTAACAATCTGTGAGGATTGAGAGGATA
GGCTGGTGCTTTGAAGAAAGGCCTTGTAAGTGACAAGACAGTCCCCTGGGAAGAAAGAGAAAGGAAATGGGCTATTGCCAAAGGACAGGT
GGCGTTAGATGGCTGTGAGGGTGACCTGGTGAGGGAAGGGTTGGAATGAGCTGCTGCAGGAGGCCAAGGGATGCCTGGGCTGGGCTGGGC
TGGGCTGGCTTAGGCTCAGGATTGCCTGGGGACAGTAGGAGCATGGCAGGAGCTGGGGCAGGTGCATAGCAGTGCAGTGGGAAGGGACAG
AGGAGATCTTAGAATTTTGAGGAAAATCTGGGACTTGAGACCTGGATTCTAACAGACCAACTGCATGTGTGTCTGTAGGTCTCAGTTTCC
ACATTCATACAGTGAGGGTGTTAAGTCAGGTAGCTGGAGACTTCCCATCGCCTCTGACACTTTTGGAGGTGATATGATACAGCCCCCGAC
CAAACCAGGCTTTGTGGGGGGTGAGAGAATACAGACACAAGTGGCAGGATTCAGATGGAAGCTTCGCAAGGCTGGGGGCCGAGGACCACC
CACTTCTCTTTCCCAGCCCTAGTTCTGGGTTCCCCAGTGGGGCAAGGGGTGGTGGAGGCAGTGCCCATGCTGGGCTGAGCCTGCAGTTTT
TGTGAGCTCTGGGCTTGTCTCCATGGGAACAGGGGTGCCTTCTTAGTGAGCTCATTTCACACAGATCGAGGGGGTATGCGTGGGGGAGTT
GTGAGTGAGCTCAGCTCCTTCAGGCCTGGCCTCTCCCAGAACAGAGTGAAGCCCCTGCCCTGGACCCCTGCTCCCTTCTACCCTTGAGGG
CCACCAATGGAAGAGCCCGCCCTTCATTCTGCAGCTCCTGCGGCCAGGCTGAGCTCTGCCCCCAACTTTGTTTTCTCTCATGTTCTCAAT
ACACTCTGCCTCAAATCCGTCTTGCTTCTTTCTTTCTTCCGTGCTGCTAGGGGTCAGGGTTCCCTTCCTCCTGCCTGATTCTAGCCTGGG
AAGTGGAGTGGGCCTGCTCAATTACTGTGTGTGAAAGTGTGGCTGTGTCCTGCGTGCTGCCTGCACCTGCCGTGTGTCTGGTTCTGCACT
GGTACAGACGTGTGCTGGGTTGGAAATGAGGGCTTCCTCTCTACAGCACTCAGGGAGCCAGAACCCTGTGCAAATCGCAACCTTTTGTTC
TTTCCTTCCCTCAGAGTTTGGCCAAAAATACTTTAGAGGATTTTTGGGGAAAATGCACTACCTCTTCTCGTTGAGGTTTGTTTGGGTTCT
TTACAAGTGGAATAGAAATTCCTCTAGCCAGCATTCGCTCTCCAGTTCCCTCAGGTCCCCTCCCTGCTCCCCATTATCTAAATTTGGCCA
TTTCCCACATTTGCCATTGTTTTCACTGTCTGGATCCTAAAAGCATGGAGTTTCTGCCCCTGGTGGGGAGGAAAGAACTGCCATCAAGGG
TCAGGAGAGCTGGGTTCTAGCCCCAGGTCTGCATCTGATTCGTGTGTGACCTCAGACAACCTCTTCCAATCTCTGGGCCTCAGTTTCCCC
TTCTGTGCAGTGAAAGGATTACAGAAGGAGGTCAGAGACCATTTGGTCTCCGACAGTCCAGGTTTGACTGTGTTCTACTTATGTATTCAC
CCCACACATGTGCCCTGCTTTGGGTCTGGGGTTGGGTTGAGTGGATGCTACTTTTTGAATTTTCACCCACCGCATTCCCAAGGAGCTCTG
GTGTGCACGGTGCATTGAGCTCTCTGTCAGAAAGTGAACAGTTCTGATTTCCTGCAGCCTTTTCGTACTGTGCACACCCCCGACTCAAAA
ACATACACACAGAGTCAGTGCCCAGGCATGGCTGTTAGGGTGAGGTCAGGCTCTGGCCCATCTCCAGATGATGGGGATCTGCTTACCACT
GCCCTCAACATTCAATCCCGTTTGAGCCCTTCTGTTTTGTAGTCTTGGCTGAATTGTTATTTCTTCCACTTGTTGGCCTCAGCATTCCCC
TTGTGGCCACCAAAGGCAGAAACAATGCTTTAGAGATTTTTAGGTAGTTATCATAGCTCTCCTGTGCAGCCTACTCTCCTGGCTGAAGAC
CCCAGGTTCCGCTGCCTTGGGTGGTTATTGACTGGCTTGGGTCATGAACTCTAGGCCCTACCTCCCTGCTCAGGGTGGCACTGTGGTCAG
GTGTTGGGTCATGCCAGAGCCCACCCTGATTTGGCATTTGGCCCTAGCCCTCCTCTTCTAGCCCTGGAGCTGGGACCTTCCTCCCAGCTC
CTCTCCCTAAACTGTGGGGTCTGCCTTCTGCGGCCAGCCTGACTGGGATGTTCCACTGGCACAGAGAAGCTCCCAGTGTCTCTGGCTCAT
GTATACACAATTCTGACCCTGGGAAGAAAACAGTGGGATCCCAGGCTGAGCCTTAACTTTCAGCTTGATGACTGGGAGCTTGGATGTCCC
TAGGGAGTCTCTAAGGGTCACTCCAGCATTAGTATCCCATGAAAAATGTCCTGCTCAGGCTGTTGTATAACATTCTTCTTTAGGTTAAAG
GGCTCCAGTTTGGAGTCTGGGCTCATCTAGCAGCTGCTACATTCTGTTTGGATAAAACATACAATTGGTGTCTATTTCCTTTGGATTGGG
AGGAATTAGAAGACTCTCAGTTGGATGAGAGGATGACTGGCTTGGTTATGGCTGATCACTGATTGGATGAAAGAATAAATCTTTGGATGG
TTCTAGATTTTGATCGGGTAGGAAGCATGGAATGGACTGGCTAGCTCTGAACTCTGGTGGATGACTGCTAGTGAATTTGGATTGGATTAA

>81255_81255_3_SGCD-SYNPO_SGCD_chr5_156022061_ENST00000447401_SYNPO_chr5_150027506_ENST00000394243_length(amino acids)=963AA_BP=162
MMPQEQYTHHRSTMPGSVGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLY
AKEIQSRPGNALYFKSARNVTVNILNDQTKVLTQLITGPKAVEAYGKKFEVKTVSGKLLFSADNNEVVVGAERLRVLALGRSTSLTEKDL
KEAKARSQQIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESHGQRGQKPSQESLRVLPSSLPGHAPGLSLSSTSLPEPGPPRHPSPQSP
DRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTT
PTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSR
EATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLER
RHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSS
HLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASP
AAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVA
SRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPG

--------------------------------------------------------------
>81255_81255_4_SGCD-SYNPO_SGCD_chr5_156022061_ENST00000517913_SYNPO_chr5_150027506_ENST00000394243_length(transcript)=7153nt_BP=864nt
GTGATATCTATTGAAGCTGGGAGGGTCACAGTATCAGTGAGTGGTCCCCCAATTTCTTCTTGAGCATCGATGAATTAGCAGTGGTGTAAT
ATTGTGGATCTGACTTCATGTGTCACTAAGAACAGGAGATCCAAGACTGCTCTTCTGGGGATGAGACTTGGAAGAAACCTCCATCCTCAG
GGATTTGAAGAAGGTTATACTGGAACCTGTGTGAAGGCTGAGACAACCGTCCCTTTTGTGGTGGCCTGAGGGGATTTTCTTAATCCCAAT
GTTGCCCTGAAATTTATGTCCAGGATTCAAAAAGTTTAGGACTGCTAAGAGACATTACTGCCGGGAGTGTTGAGTGAAGGGACCAGGTGG
AGATGATGCCTCAGGAGCAGTACACTCACCACCGGAGCACCATGCCTGGCTCTGTGGGGCCACAGGTATACAAGGTGGGGATTTATGGCT
GGCGGAAACGATGCCTGTATTTCTTTGTCCTGCTCCTCATGATTTTAATACTGGTGAACTTGGCCATGACCATCTGGATTCTCAAAGTCA
TGAACTTCACAATTGATGGAATGGGAAACCTGAGGATCACAGAAAAAGGTCTAAAGCTAGAAGGAGACTCTGAATTCTTACAACCTCTCT
ACGCCAAAGAAATCCAGTCCCGACCAGGTAATGCCCTGTACTTCAAGTCTGCCAGAAATGTTACAGTGAACATTCTCAATGACCAGACTA
AAGTGCTAACTCAGCTTATAACAGGTCCAAAAGCCGTAGAAGCTTATGGTAAAAAATTTGAGGTAAAAACTGTTTCTGGAAAATTGCTCT
TCTCTGCAGACAATAATGAAGTGGTAGTAGGAGCTGAAAGATTACGAGTTTTAGCGTTGGGCCGGAGCACTAGCCTCACGGAGAAGGATC
TGAAAGAAGCCAAGGCGCGGAGCCAGCAGATTGCAGCCCAGCTGACCACCCCTCCCAGCTCCAATTCCCGTGGCGTCCAGCTCTTCAACA
GGCGCCGGCAGAGGGTGAACGAGTTCACCTTGGAGAGCCACGGCCAGAGGGGACAGAAGCCCAGCCAGGAGTCCCTCAGAGTGCTCCCTT
CAAGCCTCCCAGGCCATGCACCGGGGCTCAGCCTGAGTTCCACCTCGCTGCCGGAGCCAGGCCCTCCACGGCACCCCAGTCCCCAGAGCC
CCGACAGAGGGGTCCCTGGCCACAGCATGGAGGGGTACTCAGAGGAGGCTAGCTTGCTGCGGCACCTGGAGAAGGTGGCCAGTGAGGAGG
AAGAGGTACCACTGGTGGTTTATCTAAAGGAGAATGCAGCACTGCTGACAGCCAATGGGCTGCACCTGTCCCAAAACCGAGAGGCCCAGC
AGTCCTCACCGGCCCCACCTCCAGCTGAGGTCCACAGCCCAGCTGCAGATGTCAACCAAAACCTTGCCTCGCCCAGTGCCACGCTCACCA
CACCAACTTCTAACAGCAGCCACAATCCGCCAGCCACCGATGTCAATCAGAACCCACCGGCAACTGTTGTCCCACAGAGCCTGCCACTTT
CTAGCATCCAACAGAATTCCTCAGAGGCCCAACTCCCATCTAATGGCACAGGGCCTGCTTCCAAACCCAGCACCCTGTGTGCTGATGGGC
AACCCCAGGCACCGGCTGAGGAGGTGAGATGCAGCACACTCCTAATTGACAAGGTATCAACTCCAGCTACCACCACCAGCACCTTCTCCA
GAGAAGCTACGCTCATCCCCAGCTCCAGGCCCCCAGCCTCAGATTTCATGTCCAGCTCCCTGCTCATTGACATCCAGCCCAACACCCTAG
TGGTGTCAGCAGATCAAGAGATGTCTGGGCGAGCAGCTGCCACCACGCCCACCAAGGTCTACAGTGAGGTCCACTTCACACTGGCCAAGC
CCCCATCAGTGGTCAACAGGACGGCCAGGCCTTTTGGGATCCAGGCGCCAGGGGGCACCAGCCAGATGGAGAGGAGCCCCATGCTAGAGA
GACGACATTTTGGGGAGAAGGCCCCGGCTCCCCAGCCCCCCAGTTTGCCAGACAGGAGCCCCCGGCCACAGAGACACATAATGTCCCGCA
GCCCCATGGTGGAAAGGAGGATGATGGGGCAGCGAAGCCCGGCCTCAGAGAGACGCCCCTTGGGGAACTTCACTGCACCCCCCACCTACA
CTGAGACCTTGTCCACAGCCCCTCTGGCTTCCTGGGTGAGGTCTCCTCCCTCATATTCTGTCCTGTATCCCAGCTCCGACCCCAAGTCTT
CTCATCTGAAGGGCCAGGCGGTTCCTGCCAGCAAGACGGGCATTCTGGAGGAGTCGATGGCCCGCCGGGGCAGCCGCAAATCCATGTTTA
CTTTCGTGGAGAAGCCCAAGGTGACCCCGAATCCAGACTTGCTGGATCTGGTACAGACAGCGGATGAGAAGCGGCGGCAGAGGGACCAGG
GGGAGGTAGGCGTGGAGGAGGAGCCCTTCGCACTGGGGGCCGAGGCCTCCAACTTCCAGCAGGAGCCAGCACCTCGTGACAGGGCCAGCC
CCGCGGCGGCGGAGGAGGTGGTACCAGAGTGGGCCTCCTGCCTCAAGTCACCCCGCATCCAGGCCAAGCCGAAGCCCAAACCCAACCAGA
ACCTCTCCGAGGCCTCTGGGAAGGGAGCTGAGCTCTACGCCCGCCGCCAGTCACGGATGGAGAAATATGTCATCGAGTCTTCAAGCCACA
CGCCAGAGCTGGCCCGCTGCCCATCACCTACCATGTCCCTGCCTTCCTCCTGGAAATACCCCACTAACGCCCCCGGGGCCTTCCGAGTGG
CATCCCGAAGCCCAGCCCGGACCCCGCCTGCCTCCCTCTACCATGGCTACCTGCCTGAGAACGGGGTCCTGCGCCCAGAGCCCACCAAGC
AGCCGCCATACCAGCTGCGCCCCTCGCTCTTTGTCCTCTCACCTATCAAGGAGCCTGCCAAGGTCTCACCAAGAGCTGCCTCGCCCGCCA
AGCCCAGCTCCTTGGACCTGGTGCCCAACCTGCCCAAGGGGGCTCTCCCTCCATCTCCTGCCCTGCCTCGGCCCTCGCGCTCCTCACCGG
GCCTCTACACCTCCCCCGGCCAGGACAGCCTGCAGCCCACTGCCGTGAGCCCTCCTTACGGCGGTGACATCTCCCCCGTGTCTCCCTCCA
GGGCGTGGTCTCCCCGAGCCAAGCAGGCCCCCAGGCCCTCCTTCTCTACCCGGAACGCCGGGATCGAGGCTCAGGTGTGGAAGCCTTCCT
TCTGCTTCAAGTAACGAACCCCACGGGGGTCCCACTGCCGGTCAAGTTCCCCTCCTTGAGGGCCAGATGGAGAGCAGATGTGGCAGGAAA
TGGCACAGAGCTGAGTGAGGAGAATGGGGAGTCCATGGTTCAAGGTCAGATGCGGCCACCAGCTGGCTTTGTGACCTTGGGCGAGTCGCC
TCCCCTCTCTGAGCTGAAGCCGCCCCTCCCCTACTACAACAGGGGTCGGACTCCATGTCTGAGCGGGGAGGAGGGTCATGGAGAGAGAAC
TGTCTGGCAGCCCTGATGCGGTAGAGGGGCATCCTCTGGCCTTTGTGAGCTGTAGGGATGCAGAGTCTGATGCCAGCGTCTTGCTGGGGG
AGTGGCCTAGAAGGGGATCCTAACAGGGACTTCTGGAGCAGACAGAGCCTGCCAGTGCCTGTGGAGTCAGCCAGCCGAGGGTCTGCCTCC
TCAGCTGCCCCAGGGGGGCCTCCCTCCTGAGGCTCAAGCTCCTGGCGTCTTTCTTCCTGTTGCTGGATTCTCACCTCCATGGGCCTGTCT
CTTCTGCCTCTGCCTTCTGGACACCGTTTCCTCTCCGCTGCTTCAGAGAGCTTTGCCTCGCCTCCGCCTGCGCTCCCCTCCAGGGTCCTT
CTGCTGGCTGCGGACTCGGCCCACCACTGCTGTCTGACGCTTTTCTTCCTGCCCCCTCTGAGGCCTGGCTCTGTTTTAGGGAGATCACTG
GGCCCAGGCCTCAGCCCCAGTTCTACCTGGCTTGCTGTCACCGCTCTAGGGGTGGGGGACGTCCCAGGGGATCCCCAGGAGAAGGAGAGC
CCTGTAGGGGGCTGTGCAGATGTGGGTGTGCCACAGGGAGGGTGGCCCCTAGCCATGTATCCATTGGCTGTTTTGGCTTCAGATTCAACC
AAGATCTGCCTGACTAAAAGAAGCCACCTCAGCGCAGTGGAACGGGGCCCAGGGGGAGGCAGGAGAGGAGGGTTCCGGTCCCATGTCACC
TTCTCATTTGCTGTGTGACTTTGGCCCACTCACATTCTCTTTGGGCCTCAGTTTTATCATTTATACAAGGAGGGCTTTTCTAGCTGTAAC
AATCTGTGAGGATTGAGAGGATAGGCTGGTGCTTTGAAGAAAGGCCTTGTAAGTGACAAGACAGTCCCCTGGGAAGAAAGAGAAAGGAAA
TGGGCTATTGCCAAAGGACAGGTGGCGTTAGATGGCTGTGAGGGTGACCTGGTGAGGGAAGGGTTGGAATGAGCTGCTGCAGGAGGCCAA
GGGATGCCTGGGCTGGGCTGGGCTGGGCTGGCTTAGGCTCAGGATTGCCTGGGGACAGTAGGAGCATGGCAGGAGCTGGGGCAGGTGCAT
AGCAGTGCAGTGGGAAGGGACAGAGGAGATCTTAGAATTTTGAGGAAAATCTGGGACTTGAGACCTGGATTCTAACAGACCAACTGCATG
TGTGTCTGTAGGTCTCAGTTTCCACATTCATACAGTGAGGGTGTTAAGTCAGGTAGCTGGAGACTTCCCATCGCCTCTGACACTTTTGGA
GGTGATATGATACAGCCCCCGACCAAACCAGGCTTTGTGGGGGGTGAGAGAATACAGACACAAGTGGCAGGATTCAGATGGAAGCTTCGC
AAGGCTGGGGGCCGAGGACCACCCACTTCTCTTTCCCAGCCCTAGTTCTGGGTTCCCCAGTGGGGCAAGGGGTGGTGGAGGCAGTGCCCA
TGCTGGGCTGAGCCTGCAGTTTTTGTGAGCTCTGGGCTTGTCTCCATGGGAACAGGGGTGCCTTCTTAGTGAGCTCATTTCACACAGATC
GAGGGGGTATGCGTGGGGGAGTTGTGAGTGAGCTCAGCTCCTTCAGGCCTGGCCTCTCCCAGAACAGAGTGAAGCCCCTGCCCTGGACCC
CTGCTCCCTTCTACCCTTGAGGGCCACCAATGGAAGAGCCCGCCCTTCATTCTGCAGCTCCTGCGGCCAGGCTGAGCTCTGCCCCCAACT
TTGTTTTCTCTCATGTTCTCAATACACTCTGCCTCAAATCCGTCTTGCTTCTTTCTTTCTTCCGTGCTGCTAGGGGTCAGGGTTCCCTTC
CTCCTGCCTGATTCTAGCCTGGGAAGTGGAGTGGGCCTGCTCAATTACTGTGTGTGAAAGTGTGGCTGTGTCCTGCGTGCTGCCTGCACC
TGCCGTGTGTCTGGTTCTGCACTGGTACAGACGTGTGCTGGGTTGGAAATGAGGGCTTCCTCTCTACAGCACTCAGGGAGCCAGAACCCT
GTGCAAATCGCAACCTTTTGTTCTTTCCTTCCCTCAGAGTTTGGCCAAAAATACTTTAGAGGATTTTTGGGGAAAATGCACTACCTCTTC
TCGTTGAGGTTTGTTTGGGTTCTTTACAAGTGGAATAGAAATTCCTCTAGCCAGCATTCGCTCTCCAGTTCCCTCAGGTCCCCTCCCTGC
TCCCCATTATCTAAATTTGGCCATTTCCCACATTTGCCATTGTTTTCACTGTCTGGATCCTAAAAGCATGGAGTTTCTGCCCCTGGTGGG
GAGGAAAGAACTGCCATCAAGGGTCAGGAGAGCTGGGTTCTAGCCCCAGGTCTGCATCTGATTCGTGTGTGACCTCAGACAACCTCTTCC
AATCTCTGGGCCTCAGTTTCCCCTTCTGTGCAGTGAAAGGATTACAGAAGGAGGTCAGAGACCATTTGGTCTCCGACAGTCCAGGTTTGA
CTGTGTTCTACTTATGTATTCACCCCACACATGTGCCCTGCTTTGGGTCTGGGGTTGGGTTGAGTGGATGCTACTTTTTGAATTTTCACC
CACCGCATTCCCAAGGAGCTCTGGTGTGCACGGTGCATTGAGCTCTCTGTCAGAAAGTGAACAGTTCTGATTTCCTGCAGCCTTTTCGTA
CTGTGCACACCCCCGACTCAAAAACATACACACAGAGTCAGTGCCCAGGCATGGCTGTTAGGGTGAGGTCAGGCTCTGGCCCATCTCCAG
ATGATGGGGATCTGCTTACCACTGCCCTCAACATTCAATCCCGTTTGAGCCCTTCTGTTTTGTAGTCTTGGCTGAATTGTTATTTCTTCC
ACTTGTTGGCCTCAGCATTCCCCTTGTGGCCACCAAAGGCAGAAACAATGCTTTAGAGATTTTTAGGTAGTTATCATAGCTCTCCTGTGC
AGCCTACTCTCCTGGCTGAAGACCCCAGGTTCCGCTGCCTTGGGTGGTTATTGACTGGCTTGGGTCATGAACTCTAGGCCCTACCTCCCT
GCTCAGGGTGGCACTGTGGTCAGGTGTTGGGTCATGCCAGAGCCCACCCTGATTTGGCATTTGGCCCTAGCCCTCCTCTTCTAGCCCTGG
AGCTGGGACCTTCCTCCCAGCTCCTCTCCCTAAACTGTGGGGTCTGCCTTCTGCGGCCAGCCTGACTGGGATGTTCCACTGGCACAGAGA
AGCTCCCAGTGTCTCTGGCTCATGTATACACAATTCTGACCCTGGGAAGAAAACAGTGGGATCCCAGGCTGAGCCTTAACTTTCAGCTTG
ATGACTGGGAGCTTGGATGTCCCTAGGGAGTCTCTAAGGGTCACTCCAGCATTAGTATCCCATGAAAAATGTCCTGCTCAGGCTGTTGTA
TAACATTCTTCTTTAGGTTAAAGGGCTCCAGTTTGGAGTCTGGGCTCATCTAGCAGCTGCTACATTCTGTTTGGATAAAACATACAATTG
GTGTCTATTTCCTTTGGATTGGGAGGAATTAGAAGACTCTCAGTTGGATGAGAGGATGACTGGCTTGGTTATGGCTGATCACTGATTGGA
TGAAAGAATAAATCTTTGGATGGTTCTAGATTTTGATCGGGTAGGAAGCATGGAATGGACTGGCTAGCTCTGAACTCTGGTGGATGACTG

>81255_81255_4_SGCD-SYNPO_SGCD_chr5_156022061_ENST00000517913_SYNPO_chr5_150027506_ENST00000394243_length(amino acids)=963AA_BP=162
MMPQEQYTHHRSTMPGSVGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLY
AKEIQSRPGNALYFKSARNVTVNILNDQTKVLTQLITGPKAVEAYGKKFEVKTVSGKLLFSADNNEVVVGAERLRVLALGRSTSLTEKDL
KEAKARSQQIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESHGQRGQKPSQESLRVLPSSLPGHAPGLSLSSTSLPEPGPPRHPSPQSP
DRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTT
PTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSR
EATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLER
RHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSS
HLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASP
AAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVA
SRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SGCD-SYNPO


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SGCD-SYNPO


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SGCD-SYNPO


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource