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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SGSM2-EIF2B4 (FusionGDB2 ID:81354)

Fusion Gene Summary for SGSM2-EIF2B4

check button Fusion gene summary
Fusion gene informationFusion gene name: SGSM2-EIF2B4
Fusion gene ID: 81354
HgeneTgene
Gene symbol

SGSM2

EIF2B4

Gene ID

9905

8890

Gene namesmall G protein signaling modulator 2eukaryotic translation initiation factor 2B subunit delta
SynonymsRUTBC1EIF-2B|EIF2B|EIF2Bdelta
Cytomap

17p13.3

2p23.3

Type of geneprotein-codingprotein-coding
Descriptionsmall G protein signaling modulator 2RUN and TBC1 domain containing 1small G protein signaling modulator 2 proteintranslation initiation factor eIF-2B subunit deltaeIF-2B GDP-GTP exchange factor subunit deltaeukaryotic translation initiation factor 2B subunit 4 deltaeukaryotic translation initiation factor 2B, subunit 4 delta, 67kDatranslation initiation factor e
Modification date2020031320200313
UniProtAcc.

Q9UI10

Ensembl transtripts involved in fusion geneENST00000268989, ENST00000426855, 
ENST00000574563, 		ENST00000347454, 
ENST00000445933, ENST00000451130, 
ENST00000493344, 
Fusion gene scores* DoF score6 X 5 X 5=1502 X 2 X 1=4
# samples 62
** MAII scorelog2(6/150*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/4*10)=2.32192809488736
Context

PubMed: SGSM2 [Title/Abstract] AND EIF2B4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSGSM2(2276807)-EIF2B4(27591330), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneEIF2B4

GO:0006413

translational initiation

16289705

TgeneEIF2B4

GO:0050852

T cell receptor signaling pathway

8626696


check buttonFusion gene breakpoints across SGSM2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EIF2B4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-FS-A1YX-06ASGSM2chr17

2276807

+EIF2B4chr2

27591330

-


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Fusion Gene ORF analysis for SGSM2-EIF2B4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000268989ENST00000347454SGSM2chr17

2276807

+EIF2B4chr2

27591330

-
In-frameENST00000268989ENST00000445933SGSM2chr17

2276807

+EIF2B4chr2

27591330

-
In-frameENST00000268989ENST00000451130SGSM2chr17

2276807

+EIF2B4chr2

27591330

-
In-frameENST00000268989ENST00000493344SGSM2chr17

2276807

+EIF2B4chr2

27591330

-
In-frameENST00000426855ENST00000347454SGSM2chr17

2276807

+EIF2B4chr2

27591330

-
In-frameENST00000426855ENST00000445933SGSM2chr17

2276807

+EIF2B4chr2

27591330

-
In-frameENST00000426855ENST00000451130SGSM2chr17

2276807

+EIF2B4chr2

27591330

-
In-frameENST00000426855ENST00000493344SGSM2chr17

2276807

+EIF2B4chr2

27591330

-
In-frameENST00000574563ENST00000347454SGSM2chr17

2276807

+EIF2B4chr2

27591330

-
In-frameENST00000574563ENST00000445933SGSM2chr17

2276807

+EIF2B4chr2

27591330

-
In-frameENST00000574563ENST00000451130SGSM2chr17

2276807

+EIF2B4chr2

27591330

-
In-frameENST00000574563ENST00000493344SGSM2chr17

2276807

+EIF2B4chr2

27591330

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000268989SGSM2chr172276807+ENST00000347454EIF2B4chr227591330-3399227717733501057
ENST00000268989SGSM2chr172276807+ENST00000445933EIF2B4chr227591330-3370227717733501057
ENST00000268989SGSM2chr172276807+ENST00000451130EIF2B4chr227591330-3352227717733501057
ENST00000268989SGSM2chr172276807+ENST00000493344EIF2B4chr227591330-3352227717733501057
ENST00000426855SGSM2chr172276807+ENST00000347454EIF2B4chr227591330-3262214017532131012
ENST00000426855SGSM2chr172276807+ENST00000445933EIF2B4chr227591330-3233214017532131012
ENST00000426855SGSM2chr172276807+ENST00000451130EIF2B4chr227591330-3215214017532131013
ENST00000426855SGSM2chr172276807+ENST00000493344EIF2B4chr227591330-3215214017532131013
ENST00000574563SGSM2chr172276807+ENST00000347454EIF2B4chr227591330-315420326731051012
ENST00000574563SGSM2chr172276807+ENST00000445933EIF2B4chr227591330-312520326731051012
ENST00000574563SGSM2chr172276807+ENST00000451130EIF2B4chr227591330-310720326731051013
ENST00000574563SGSM2chr172276807+ENST00000493344EIF2B4chr227591330-310720326731051013

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000268989ENST00000347454SGSM2chr172276807+EIF2B4chr227591330-0.0045919580.995408
ENST00000268989ENST00000445933SGSM2chr172276807+EIF2B4chr227591330-0.0047000540.99529994
ENST00000268989ENST00000451130SGSM2chr172276807+EIF2B4chr227591330-0.0049927580.9950073
ENST00000268989ENST00000493344SGSM2chr172276807+EIF2B4chr227591330-0.0049927580.9950073
ENST00000426855ENST00000347454SGSM2chr172276807+EIF2B4chr227591330-0.0054933780.99450666
ENST00000426855ENST00000445933SGSM2chr172276807+EIF2B4chr227591330-0.0055925150.99440753
ENST00000426855ENST00000451130SGSM2chr172276807+EIF2B4chr227591330-0.0059470930.99405295
ENST00000426855ENST00000493344SGSM2chr172276807+EIF2B4chr227591330-0.0059470930.99405295
ENST00000574563ENST00000347454SGSM2chr172276807+EIF2B4chr227591330-0.0047025730.9952975
ENST00000574563ENST00000445933SGSM2chr172276807+EIF2B4chr227591330-0.0048112480.9951887
ENST00000574563ENST00000451130SGSM2chr172276807+EIF2B4chr227591330-0.0051177240.99488235
ENST00000574563ENST00000493344SGSM2chr172276807+EIF2B4chr227591330-0.0051177240.99488235

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Fusion Genomic Features for SGSM2-EIF2B4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SGSM2-EIF2B4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:2276807/chr2:27591330)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EIF2B4

Q9UI10

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSGSM2chr17:2276807chr2:27591330ENST00000268989+172434_1917001052.0DomainRUN
HgeneSGSM2chr17:2276807chr2:27591330ENST00000426855+162334_1916551007.0DomainRUN
HgeneSGSM2chr17:2276807chr2:27591330ENST00000574563+162334_191655988.0DomainRUN

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSGSM2chr17:2276807chr2:27591330ENST00000268989+1724566_9397001052.0DomainRab-GAP TBC
HgeneSGSM2chr17:2276807chr2:27591330ENST00000426855+1623566_9396551007.0DomainRab-GAP TBC
HgeneSGSM2chr17:2276807chr2:27591330ENST00000574563+1623566_939655988.0DomainRab-GAP TBC


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Fusion Gene Sequence for SGSM2-EIF2B4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>81354_81354_1_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000268989_EIF2B4_chr2_27591330_ENST00000347454_length(transcript)=3399nt_BP=2277nt
GGAAGATGGCTGCGGAGCCGAGCACCGGGCAGTGGCTGCGGCGGCGGCGGCGGCGGCGGGCCGGGAGCGCGGCGGGCGGGGGCTCCGCCT
TGCGCGTGGGGCGCTGAGCCGAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATG
GGCAGCGCAGAGGACGCAGTCAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAG
TTTGTGCATGAAGACAGCAGCCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGC
TTCCTGCGCAGTGACAAGATGGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAG
CTGCAGCAACAAGCAGAGGGCAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCC
CTCAGCCCTCAGGCCTTGAAACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAAC
TGCAGCAAGTACTACGAGAAGGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTG
GAATACACTAAGCTCAAGACAGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCT
ACTCGCCAGGACTCCCCTGCAAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCC
TGTGCCCGCGAGTGTGTGGAGTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAG
GATATGGAGGCGGTCCCTGGCTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGG
ACTCTGGGGGACTCCGAGCTGGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCAC
CAGCAAAAGAGCGGTGGCACGCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTG
TCCTTTCTGTCCTGTCTGGAGAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTC
CCCAAGCTACGGAAACGAAGCAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATC
TACCCCGGCCACAGGCACGAGCACATCACTATTAACTACCACCACCTAGCGGCCAGCCGCGCGGCCTCGGTGGACGATGATGAGGAAGAG
GAGGATAAACTGCACGCGATGCTCTCAATGATCTGCTCGCGGAACCTCACAGCTCCCAATCCGATGAAAGACGCTGGTGACATGATCGAG
ATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCTGTGCAGTCAGGGCTCCTCCTGCCTCTCCTGCTCCTCCAGCAGC
TCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTTGCCGCTCAGGCTACTGTGTGAGAGTATGAAGAGGCAGATCGTG
TCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCACGGTGCGGACCCACCTGTCGGCGCTGGTGCACCATAGCGTTATC
CCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGTGTGGAGCAAGTATCAGAAGGACAAAAAGAACTACAAAGAGCTG
GAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCGCAAGGACGTCTGGCCCTTTCTGCTTGGCCACTACAAGTTCGGC
ATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAGGTACCAGCAGGTGTTGGCAGAGTGGAAGGCCTGCGAGGTGGTG
GTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTTCTCCTCAGGCAGCAGCATCGACAGCCACGTGCAGCGCCTCATC
CACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTATGGATCCAAAGTCAGTCTCTTCTCTCACCTACCCCAGTACAGC
AGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGATCCACCCAGCCATGGTGCGACTCGGCCTGCAGTACTCCCAGGGC
CTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTTGCAGCAGGTGATTCAGGATTACACAACACCGCCTAATGAAGAA
CTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCTGACTCAGTGCCGTCCCCTGTCAGCGAGCATGCACAACGCCATC
AAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGAAGAGGAGGCCAAGTCAGAACTTCGAGCAGCCATTGATCGGTAT
GTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGCTTACCAGAAGATCAGTAATGGAGATGTGATCCTGGTATATGGA
TGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGGCCGGCGGTTTCGGGTGGTAGTGGTGGACAGCCGGCCATGGCTG
GAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGCCTCCTACCTGCTGATTCCTGCAGCCTCCTATGTGCTCCCAGAG
GTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTCTGTGATGTCACGGGTAGGGACAGCACAGTTAGCCCTGGTGGCT
CGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTTCTGTGAGCGTGTGCAGACTGATGCCTTTGTCTCTAATGAGCTA
GATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCTGGCTAACTGGCAGAACCACGCATCCCTACGGTTGTTGAATCTA
GTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGAGCTGGGGATGATCCCTTGCAGTTCTGTACCTGTTGTTCTACGA

>81354_81354_1_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000268989_EIF2B4_chr2_27591330_ENST00000347454_length(amino acids)=1057AA_BP=700
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHITINYHHLAASRAASVDDDEE
EEDKLHAMLSMICSRNLTAPNPMKDAGDMIEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQI
VSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKF
GMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQY
SRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNA
IKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPW
LEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNE

--------------------------------------------------------------
>81354_81354_2_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000268989_EIF2B4_chr2_27591330_ENST00000445933_length(transcript)=3370nt_BP=2277nt
GGAAGATGGCTGCGGAGCCGAGCACCGGGCAGTGGCTGCGGCGGCGGCGGCGGCGGCGGGCCGGGAGCGCGGCGGGCGGGGGCTCCGCCT
TGCGCGTGGGGCGCTGAGCCGAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATG
GGCAGCGCAGAGGACGCAGTCAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAG
TTTGTGCATGAAGACAGCAGCCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGC
TTCCTGCGCAGTGACAAGATGGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAG
CTGCAGCAACAAGCAGAGGGCAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCC
CTCAGCCCTCAGGCCTTGAAACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAAC
TGCAGCAAGTACTACGAGAAGGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTG
GAATACACTAAGCTCAAGACAGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCT
ACTCGCCAGGACTCCCCTGCAAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCC
TGTGCCCGCGAGTGTGTGGAGTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAG
GATATGGAGGCGGTCCCTGGCTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGG
ACTCTGGGGGACTCCGAGCTGGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCAC
CAGCAAAAGAGCGGTGGCACGCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTG
TCCTTTCTGTCCTGTCTGGAGAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTC
CCCAAGCTACGGAAACGAAGCAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATC
TACCCCGGCCACAGGCACGAGCACATCACTATTAACTACCACCACCTAGCGGCCAGCCGCGCGGCCTCGGTGGACGATGATGAGGAAGAG
GAGGATAAACTGCACGCGATGCTCTCAATGATCTGCTCGCGGAACCTCACAGCTCCCAATCCGATGAAAGACGCTGGTGACATGATCGAG
ATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCTGTGCAGTCAGGGCTCCTCCTGCCTCTCCTGCTCCTCCAGCAGC
TCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTTGCCGCTCAGGCTACTGTGTGAGAGTATGAAGAGGCAGATCGTG
TCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCACGGTGCGGACCCACCTGTCGGCGCTGGTGCACCATAGCGTTATC
CCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGTGTGGAGCAAGTATCAGAAGGACAAAAAGAACTACAAAGAGCTG
GAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCGCAAGGACGTCTGGCCCTTTCTGCTTGGCCACTACAAGTTCGGC
ATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAGGTACCAGCAGGTGTTGGCAGAGTGGAAGGCCTGCGAGGTGGTG
GTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTTCTCCTCAGGCAGCAGCATCGACAGCCACGTGCAGCGCCTCATC
CACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTATGGATCCAAAGTCAGTCTCTTCTCTCACCTACCCCAGTACAGC
AGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGATCCACCCAGCCATGGTGCGACTCGGCCTGCAGTACTCCCAGGGC
CTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTTGCAGCAGGTGATTCAGGATTACACAACACCGCCTAATGAAGAA
CTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCTGACTCAGTGCCGTCCCCTGTCAGCGAGCATGCACAACGCCATC
AAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGAAGAGGAGGCCAAGTCAGAACTTCGAGCAGCCATTGATCGGTAT
GTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGCTTACCAGAAGATCAGTAATGGAGATGTGATCCTGGTATATGGA
TGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGGCCGGCGGTTTCGGGTGGTAGTGGTGGACAGCCGGCCATGGCTG
GAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGCCTCCTACCTGCTGATTCCTGCAGCCTCCTATGTGCTCCCAGAG
GTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTCTGTGATGTCACGGGTAGGGACAGCACAGTTAGCCCTGGTGGCT
CGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTTCTGTGAGCGTGTGCAGACTGATGCCTTTGTCTCTAATGAGCTA
GATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCTGGCTAACTGGCAGAACCACGCATCCCTACGGTTGTTGAATCTA
GTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGAGCTGGGGATGATCCCTTGCAGTTCTGTACCTGTTGTTCTACGA

>81354_81354_2_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000268989_EIF2B4_chr2_27591330_ENST00000445933_length(amino acids)=1057AA_BP=700
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHITINYHHLAASRAASVDDDEE
EEDKLHAMLSMICSRNLTAPNPMKDAGDMIEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQI
VSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKF
GMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQY
SRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNA
IKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPW
LEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNE

--------------------------------------------------------------
>81354_81354_3_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000268989_EIF2B4_chr2_27591330_ENST00000451130_length(transcript)=3352nt_BP=2277nt
GGAAGATGGCTGCGGAGCCGAGCACCGGGCAGTGGCTGCGGCGGCGGCGGCGGCGGCGGGCCGGGAGCGCGGCGGGCGGGGGCTCCGCCT
TGCGCGTGGGGCGCTGAGCCGAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATG
GGCAGCGCAGAGGACGCAGTCAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAG
TTTGTGCATGAAGACAGCAGCCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGC
TTCCTGCGCAGTGACAAGATGGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAG
CTGCAGCAACAAGCAGAGGGCAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCC
CTCAGCCCTCAGGCCTTGAAACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAAC
TGCAGCAAGTACTACGAGAAGGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTG
GAATACACTAAGCTCAAGACAGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCT
ACTCGCCAGGACTCCCCTGCAAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCC
TGTGCCCGCGAGTGTGTGGAGTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAG
GATATGGAGGCGGTCCCTGGCTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGG
ACTCTGGGGGACTCCGAGCTGGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCAC
CAGCAAAAGAGCGGTGGCACGCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTG
TCCTTTCTGTCCTGTCTGGAGAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTC
CCCAAGCTACGGAAACGAAGCAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATC
TACCCCGGCCACAGGCACGAGCACATCACTATTAACTACCACCACCTAGCGGCCAGCCGCGCGGCCTCGGTGGACGATGATGAGGAAGAG
GAGGATAAACTGCACGCGATGCTCTCAATGATCTGCTCGCGGAACCTCACAGCTCCCAATCCGATGAAAGACGCTGGTGACATGATCGAG
ATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCTGTGCAGTCAGGGCTCCTCCTGCCTCTCCTGCTCCTCCAGCAGC
TCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTTGCCGCTCAGGCTACTGTGTGAGAGTATGAAGAGGCAGATCGTG
TCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCACGGTGCGGACCCACCTGTCGGCGCTGGTGCACCATAGCGTTATC
CCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGTGTGGAGCAAGTATCAGAAGGACAAAAAGAACTACAAAGAGCTG
GAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCGCAAGGACGTCTGGCCCTTTCTGCTTGGCCACTACAAGTTCGGC
ATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAGGTACCAGCAGGTGTTGGCAGAGTGGAAGGCCTGCGAGGTGGTG
GTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTTCTCCTCAGGCAGCAGCATCGACAGCCACGTGCAGCGCCTCATC
CACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTATGGATCCAAAGTCAGTCTCTTCTCTCACCTACCCCAGTACAGC
AGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGATCCACCCAGCCATGGTGCGACTCGGCCTGCAGTACTCCCAGGGC
CTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTTGCAGCAGGTGATTCAGGATTACACAACACCGCCTAATGAAGAA
CTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCTGACTCAGTGCCGTCCCCTGTCAGCGAGCATGCACAACGCCATC
AAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGAAGAGGAGGCCAAGTCAGAACTTCGAGCAGCCATTGATCGGTAT
GTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGCTTACCAGAAGATCAGTAATGGAGATGTGATCCTGGTATATGGA
TGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGGCCGGCGGTTTCGGGTGGTAGTGGTGGACAGCCGGCCATGGCTG
GAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGCCTCCTACCTGCTGATTCCTGCAGCCTCCTATGTGCTCCCAGAG
GTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTCTGTGATGTCACGGGTAGGGACAGCACAGTTAGCCCTGGTGGCT
CGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTTCTGTGAGCGTGTGCAGACTGATGCCTTTGTCTCTAATGAGCTA
GATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCTGGCTAACTGGCAGAACCACGCATCCCTACGGTTGTTGAATCTA
GTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGAGCTGGGGATGATCCCTTGCAGTTCTGTACCTGTTGTTCTACGA

>81354_81354_3_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000268989_EIF2B4_chr2_27591330_ENST00000451130_length(amino acids)=1057AA_BP=700
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHITINYHHLAASRAASVDDDEE
EEDKLHAMLSMICSRNLTAPNPMKDAGDMIEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQI
VSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKF
GMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQY
SRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNA
IKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPW
LEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNE

--------------------------------------------------------------
>81354_81354_4_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000268989_EIF2B4_chr2_27591330_ENST00000493344_length(transcript)=3352nt_BP=2277nt
GGAAGATGGCTGCGGAGCCGAGCACCGGGCAGTGGCTGCGGCGGCGGCGGCGGCGGCGGGCCGGGAGCGCGGCGGGCGGGGGCTCCGCCT
TGCGCGTGGGGCGCTGAGCCGAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATG
GGCAGCGCAGAGGACGCAGTCAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAG
TTTGTGCATGAAGACAGCAGCCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGC
TTCCTGCGCAGTGACAAGATGGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAG
CTGCAGCAACAAGCAGAGGGCAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCC
CTCAGCCCTCAGGCCTTGAAACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAAC
TGCAGCAAGTACTACGAGAAGGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTG
GAATACACTAAGCTCAAGACAGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCT
ACTCGCCAGGACTCCCCTGCAAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCC
TGTGCCCGCGAGTGTGTGGAGTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAG
GATATGGAGGCGGTCCCTGGCTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGG
ACTCTGGGGGACTCCGAGCTGGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCAC
CAGCAAAAGAGCGGTGGCACGCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTG
TCCTTTCTGTCCTGTCTGGAGAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTC
CCCAAGCTACGGAAACGAAGCAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATC
TACCCCGGCCACAGGCACGAGCACATCACTATTAACTACCACCACCTAGCGGCCAGCCGCGCGGCCTCGGTGGACGATGATGAGGAAGAG
GAGGATAAACTGCACGCGATGCTCTCAATGATCTGCTCGCGGAACCTCACAGCTCCCAATCCGATGAAAGACGCTGGTGACATGATCGAG
ATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCTGTGCAGTCAGGGCTCCTCCTGCCTCTCCTGCTCCTCCAGCAGC
TCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTTGCCGCTCAGGCTACTGTGTGAGAGTATGAAGAGGCAGATCGTG
TCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCACGGTGCGGACCCACCTGTCGGCGCTGGTGCACCATAGCGTTATC
CCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGTGTGGAGCAAGTATCAGAAGGACAAAAAGAACTACAAAGAGCTG
GAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCGCAAGGACGTCTGGCCCTTTCTGCTTGGCCACTACAAGTTCGGC
ATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAGGTACCAGCAGGTGTTGGCAGAGTGGAAGGCCTGCGAGGTGGTG
GTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTTCTCCTCAGGCAGCAGCATCGACAGCCACGTGCAGCGCCTCATC
CACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTATGGATCCAAAGTCAGTCTCTTCTCTCACCTACCCCAGTACAGC
AGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGATCCACCCAGCCATGGTGCGACTCGGCCTGCAGTACTCCCAGGGC
CTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTTGCAGCAGGTGATTCAGGATTACACAACACCGCCTAATGAAGAA
CTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCTGACTCAGTGCCGTCCCCTGTCAGCGAGCATGCACAACGCCATC
AAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGAAGAGGAGGCCAAGTCAGAACTTCGAGCAGCCATTGATCGGTAT
GTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGCTTACCAGAAGATCAGTAATGGAGATGTGATCCTGGTATATGGA
TGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGGCCGGCGGTTTCGGGTGGTAGTGGTGGACAGCCGGCCATGGCTG
GAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGCCTCCTACCTGCTGATTCCTGCAGCCTCCTATGTGCTCCCAGAG
GTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTCTGTGATGTCACGGGTAGGGACAGCACAGTTAGCCCTGGTGGCT
CGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTTCTGTGAGCGTGTGCAGACTGATGCCTTTGTCTCTAATGAGCTA
GATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCTGGCTAACTGGCAGAACCACGCATCCCTACGGTTGTTGAATCTA
GTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGAGCTGGGGATGATCCCTTGCAGTTCTGTACCTGTTGTTCTACGA

>81354_81354_4_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000268989_EIF2B4_chr2_27591330_ENST00000493344_length(amino acids)=1057AA_BP=700
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHITINYHHLAASRAASVDDDEE
EEDKLHAMLSMICSRNLTAPNPMKDAGDMIEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQI
VSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKF
GMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQY
SRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNA
IKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPW
LEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNE

--------------------------------------------------------------
>81354_81354_5_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000426855_EIF2B4_chr2_27591330_ENST00000347454_length(transcript)=3262nt_BP=2140nt
AAGATGGCTGCGGAGCCGAGCACCGGGCAGTGGCTGCGGCGGCGGCGGCGGCGGCGGGCCGGGAGCGCGGCGGGCGGGGGCTCCGCCTTG
CGCGTGGGGCGCTGAGCCGAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATGGG
CAGCGCAGAGGACGCAGTCAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAGTT
TGTGCATGAAGACAGCAGCCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGCTT
CCTGCGCAGTGACAAGATGGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAGCT
GCAGCAACAAGCAGAGGGCAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCCCT
CAGCCCTCAGGCCTTGAAACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAACTG
CAGCAAGTACTACGAGAAGGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTGGA
ATACACTAAGCTCAAGACAGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCTAC
TCGCCAGGACTCCCCTGCAAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCCTG
TGCCCGCGAGTGTGTGGAGTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAGGA
TATGGAGGCGGTCCCTGGCTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGGAC
TCTGGGGGACTCCGAGCTGGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCACCA
GCAAAAGAGCGGTGGCACGCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTGTC
CTTTCTGTCCTGTCTGGAGAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTCCC
CAAGCTACGGAAACGAAGCAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATCTA
CCCCGGCCACAGGCACGAGCACAACGCTGGTGACATGATCGAGATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCT
GTGCAGTCAGGGCTCCTCCTGCCTCTCCTGCTCCTCCAGCAGCTCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTT
GCCGCTCAGGCTACTGTGTGAGAGTATGAAGAGGCAGATCGTGTCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCAC
GGTGCGGACCCACCTGTCGGCGCTGGTGCACCATAGCGTTATCCCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGT
GTGGAGCAAGTATCAGAAGGACAAAAAGAACTACAAAGAGCTGGAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCG
CAAGGACGTCTGGCCCTTTCTGCTTGGCCACTACAAGTTCGGCATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAG
GTACCAGCAGGTGTTGGCAGAGTGGAAGGCCTGCGAGGTGGTGGTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTT
CTCCTCAGGCAGCAGCATCGACAGCCACGTGCAGCGCCTCATCCACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTA
TGGATCCAAAGTCAGTCTCTTCTCTCACCTACCCCAGTACAGCAGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGAT
CCACCCAGCCATGGTGCGACTCGGCCTGCAGTACTCCCAGGGCCTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTT
GCAGCAGGTGATTCAGGATTACACAACACCGCCTAATGAAGAACTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCT
GACTCAGTGCCGTCCCCTGTCAGCGAGCATGCACAACGCCATCAAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGA
AGAGGAGGCCAAGTCAGAACTTCGAGCAGCCATTGATCGGTATGTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGC
TTACCAGAAGATCAGTAATGGAGATGTGATCCTGGTATATGGATGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGG
CCGGCGGTTTCGGGTGGTAGTGGTGGACAGCCGGCCATGGCTGGAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGC
CTCCTACCTGCTGATTCCTGCAGCCTCCTATGTGCTCCCAGAGGTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTC
TGTGATGTCACGGGTAGGGACAGCACAGTTAGCCCTGGTGGCTCGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTT
CTGTGAGCGTGTGCAGACTGATGCCTTTGTCTCTAATGAGCTAGATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCT
GGCTAACTGGCAGAACCACGCATCCCTACGGTTGTTGAATCTAGTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGA
GCTGGGGATGATCCCTTGCAGTTCTGTACCTGTTGTTCTACGAGTCAAGAGCAGTGACCAGTGACGGGGGAAACACAGGGTTAATAAATG

>81354_81354_5_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000426855_EIF2B4_chr2_27591330_ENST00000347454_length(amino acids)=1012AA_BP=655
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDMIEMQGFGPSLPAWHLE
PLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK
DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRT
KFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLR
ALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISR
FAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLAN
GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVI

--------------------------------------------------------------
>81354_81354_6_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000426855_EIF2B4_chr2_27591330_ENST00000445933_length(transcript)=3233nt_BP=2140nt
AAGATGGCTGCGGAGCCGAGCACCGGGCAGTGGCTGCGGCGGCGGCGGCGGCGGCGGGCCGGGAGCGCGGCGGGCGGGGGCTCCGCCTTG
CGCGTGGGGCGCTGAGCCGAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATGGG
CAGCGCAGAGGACGCAGTCAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAGTT
TGTGCATGAAGACAGCAGCCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGCTT
CCTGCGCAGTGACAAGATGGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAGCT
GCAGCAACAAGCAGAGGGCAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCCCT
CAGCCCTCAGGCCTTGAAACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAACTG
CAGCAAGTACTACGAGAAGGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTGGA
ATACACTAAGCTCAAGACAGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCTAC
TCGCCAGGACTCCCCTGCAAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCCTG
TGCCCGCGAGTGTGTGGAGTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAGGA
TATGGAGGCGGTCCCTGGCTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGGAC
TCTGGGGGACTCCGAGCTGGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCACCA
GCAAAAGAGCGGTGGCACGCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTGTC
CTTTCTGTCCTGTCTGGAGAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTCCC
CAAGCTACGGAAACGAAGCAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATCTA
CCCCGGCCACAGGCACGAGCACAACGCTGGTGACATGATCGAGATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCT
GTGCAGTCAGGGCTCCTCCTGCCTCTCCTGCTCCTCCAGCAGCTCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTT
GCCGCTCAGGCTACTGTGTGAGAGTATGAAGAGGCAGATCGTGTCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCAC
GGTGCGGACCCACCTGTCGGCGCTGGTGCACCATAGCGTTATCCCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGT
GTGGAGCAAGTATCAGAAGGACAAAAAGAACTACAAAGAGCTGGAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCG
CAAGGACGTCTGGCCCTTTCTGCTTGGCCACTACAAGTTCGGCATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAG
GTACCAGCAGGTGTTGGCAGAGTGGAAGGCCTGCGAGGTGGTGGTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTT
CTCCTCAGGCAGCAGCATCGACAGCCACGTGCAGCGCCTCATCCACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTA
TGGATCCAAAGTCAGTCTCTTCTCTCACCTACCCCAGTACAGCAGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGAT
CCACCCAGCCATGGTGCGACTCGGCCTGCAGTACTCCCAGGGCCTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTT
GCAGCAGGTGATTCAGGATTACACAACACCGCCTAATGAAGAACTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCT
GACTCAGTGCCGTCCCCTGTCAGCGAGCATGCACAACGCCATCAAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGA
AGAGGAGGCCAAGTCAGAACTTCGAGCAGCCATTGATCGGTATGTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGC
TTACCAGAAGATCAGTAATGGAGATGTGATCCTGGTATATGGATGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGG
CCGGCGGTTTCGGGTGGTAGTGGTGGACAGCCGGCCATGGCTGGAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGC
CTCCTACCTGCTGATTCCTGCAGCCTCCTATGTGCTCCCAGAGGTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTC
TGTGATGTCACGGGTAGGGACAGCACAGTTAGCCCTGGTGGCTCGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTT
CTGTGAGCGTGTGCAGACTGATGCCTTTGTCTCTAATGAGCTAGATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCT
GGCTAACTGGCAGAACCACGCATCCCTACGGTTGTTGAATCTAGTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGA

>81354_81354_6_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000426855_EIF2B4_chr2_27591330_ENST00000445933_length(amino acids)=1012AA_BP=655
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDMIEMQGFGPSLPAWHLE
PLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK
DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRT
KFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLR
ALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISR
FAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLAN
GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVI

--------------------------------------------------------------
>81354_81354_7_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000426855_EIF2B4_chr2_27591330_ENST00000451130_length(transcript)=3215nt_BP=2140nt
AAGATGGCTGCGGAGCCGAGCACCGGGCAGTGGCTGCGGCGGCGGCGGCGGCGGCGGGCCGGGAGCGCGGCGGGCGGGGGCTCCGCCTTG
CGCGTGGGGCGCTGAGCCGAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATGGG
CAGCGCAGAGGACGCAGTCAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAGTT
TGTGCATGAAGACAGCAGCCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGCTT
CCTGCGCAGTGACAAGATGGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAGCT
GCAGCAACAAGCAGAGGGCAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCCCT
CAGCCCTCAGGCCTTGAAACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAACTG
CAGCAAGTACTACGAGAAGGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTGGA
ATACACTAAGCTCAAGACAGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCTAC
TCGCCAGGACTCCCCTGCAAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCCTG
TGCCCGCGAGTGTGTGGAGTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAGGA
TATGGAGGCGGTCCCTGGCTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGGAC
TCTGGGGGACTCCGAGCTGGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCACCA
GCAAAAGAGCGGTGGCACGCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTGTC
CTTTCTGTCCTGTCTGGAGAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTCCC
CAAGCTACGGAAACGAAGCAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATCTA
CCCCGGCCACAGGCACGAGCACAACGCTGGTGACATGATCGAGATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCT
GTGCAGTCAGGGCTCCTCCTGCCTCTCCTGCTCCTCCAGCAGCTCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTT
GCCGCTCAGGCTACTGTGTGAGAGTATGAAGAGGCAGATCGTGTCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCAC
GGTGCGGACCCACCTGTCGGCGCTGGTGCACCATAGCGTTATCCCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGT
GTGGAGCAAGTATCAGAAGGACAAAAAGAACTACAAAGAGCTGGAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCG
CAAGGACGTCTGGCCCTTTCTGCTTGGCCACTACAAGTTCGGCATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAG
GTACCAGCAGGTGTTGGCAGAGTGGAAGGCCTGCGAGGTGGTGGTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTT
CTCCTCAGGCAGCAGCATCGACAGCCACGTGCAGCGCCTCATCCACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTA
TGGATCCAAAGTCAGTCTCTTCTCTCACCTACCCCAGTACAGCAGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGAT
CCACCCAGCCATGGTGCGACTCGGCCTGCAGTACTCCCAGGGCCTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTT
GCAGCAGGTGATTCAGGATTACACAACACCGCCTAATGAAGAACTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCT
GACTCAGTGCCGTCCCCTGTCAGCGAGCATGCACAACGCCATCAAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGA
AGAGGAGGCCAAGTCAGAACTTCGAGCAGCCATTGATCGGTATGTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGC
TTACCAGAAGATCAGTAATGGAGATGTGATCCTGGTATATGGATGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGG
CCGGCGGTTTCGGGTGGTAGTGGTGGACAGCCGGCCATGGCTGGAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGC
CTCCTACCTGCTGATTCCTGCAGCCTCCTATGTGCTCCCAGAGGTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTC
TGTGATGTCACGGGTAGGGACAGCACAGTTAGCCCTGGTGGCTCGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTT
CTGTGAGCGTGTGCAGACTGATGCCTTTGTCTCTAATGAGCTAGATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCT
GGCTAACTGGCAGAACCACGCATCCCTACGGTTGTTGAATCTAGTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGA

>81354_81354_7_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000426855_EIF2B4_chr2_27591330_ENST00000451130_length(amino acids)=1013AA_BP=655
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDMIEMQGFGPSLPAWHLE
PLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK
DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRT
KFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLR
ALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISR
FAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLAN
GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVI

--------------------------------------------------------------
>81354_81354_8_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000426855_EIF2B4_chr2_27591330_ENST00000493344_length(transcript)=3215nt_BP=2140nt
AAGATGGCTGCGGAGCCGAGCACCGGGCAGTGGCTGCGGCGGCGGCGGCGGCGGCGGGCCGGGAGCGCGGCGGGCGGGGGCTCCGCCTTG
CGCGTGGGGCGCTGAGCCGAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATGGG
CAGCGCAGAGGACGCAGTCAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAGTT
TGTGCATGAAGACAGCAGCCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGCTT
CCTGCGCAGTGACAAGATGGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAGCT
GCAGCAACAAGCAGAGGGCAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCCCT
CAGCCCTCAGGCCTTGAAACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAACTG
CAGCAAGTACTACGAGAAGGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTGGA
ATACACTAAGCTCAAGACAGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCTAC
TCGCCAGGACTCCCCTGCAAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCCTG
TGCCCGCGAGTGTGTGGAGTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAGGA
TATGGAGGCGGTCCCTGGCTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGGAC
TCTGGGGGACTCCGAGCTGGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCACCA
GCAAAAGAGCGGTGGCACGCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTGTC
CTTTCTGTCCTGTCTGGAGAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTCCC
CAAGCTACGGAAACGAAGCAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATCTA
CCCCGGCCACAGGCACGAGCACAACGCTGGTGACATGATCGAGATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCT
GTGCAGTCAGGGCTCCTCCTGCCTCTCCTGCTCCTCCAGCAGCTCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTT
GCCGCTCAGGCTACTGTGTGAGAGTATGAAGAGGCAGATCGTGTCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCAC
GGTGCGGACCCACCTGTCGGCGCTGGTGCACCATAGCGTTATCCCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGT
GTGGAGCAAGTATCAGAAGGACAAAAAGAACTACAAAGAGCTGGAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCG
CAAGGACGTCTGGCCCTTTCTGCTTGGCCACTACAAGTTCGGCATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAG
GTACCAGCAGGTGTTGGCAGAGTGGAAGGCCTGCGAGGTGGTGGTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTT
CTCCTCAGGCAGCAGCATCGACAGCCACGTGCAGCGCCTCATCCACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTA
TGGATCCAAAGTCAGTCTCTTCTCTCACCTACCCCAGTACAGCAGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGAT
CCACCCAGCCATGGTGCGACTCGGCCTGCAGTACTCCCAGGGCCTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTT
GCAGCAGGTGATTCAGGATTACACAACACCGCCTAATGAAGAACTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCT
GACTCAGTGCCGTCCCCTGTCAGCGAGCATGCACAACGCCATCAAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGA
AGAGGAGGCCAAGTCAGAACTTCGAGCAGCCATTGATCGGTATGTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGC
TTACCAGAAGATCAGTAATGGAGATGTGATCCTGGTATATGGATGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGG
CCGGCGGTTTCGGGTGGTAGTGGTGGACAGCCGGCCATGGCTGGAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGC
CTCCTACCTGCTGATTCCTGCAGCCTCCTATGTGCTCCCAGAGGTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTC
TGTGATGTCACGGGTAGGGACAGCACAGTTAGCCCTGGTGGCTCGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTT
CTGTGAGCGTGTGCAGACTGATGCCTTTGTCTCTAATGAGCTAGATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCT
GGCTAACTGGCAGAACCACGCATCCCTACGGTTGTTGAATCTAGTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGA

>81354_81354_8_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000426855_EIF2B4_chr2_27591330_ENST00000493344_length(amino acids)=1013AA_BP=655
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDMIEMQGFGPSLPAWHLE
PLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK
DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRT
KFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLR
ALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISR
FAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLAN
GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVI

--------------------------------------------------------------
>81354_81354_9_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000574563_EIF2B4_chr2_27591330_ENST00000347454_length(transcript)=3154nt_BP=2032nt
GAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATGGGCAGCGCAGAGGACGCAGT
CAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAGTTTGTGCATGAAGACAGCAG
CCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGCTTCCTGCGCAGTGACAAGAT
GGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAGCTGCAGCAACAAGCAGAGGG
CAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCCCTCAGCCCTCAGGCCTTGAA
ACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAACTGCAGCAAGTACTACGAGAA
GGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTGGAATACACTAAGCTCAAGAC
AGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCTACTCGCCAGGACTCCCCTGC
AAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCCTGTGCCCGCGAGTGTGTGGA
GTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAGGATATGGAGGCGGTCCCTGG
CTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGGACTCTGGGGGACTCCGAGCT
GGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCACCAGCAAAAGAGCGGTGGCAC
GCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTGTCCTTTCTGTCCTGTCTGGA
GAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTCCCCAAGCTACGGAAACGAAG
CAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATCTACCCCGGCCACAGGCACGA
GCACAACGCTGGTGACATGATCGAGATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCTGTGCAGTCAGGGCTCCTC
CTGCCTCTCCTGCTCCTCCAGCAGCTCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTTGCCGCTCAGGCTACTGTG
TGAGAGTATGAAGAGGCAGATCGTGTCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCACGGTGCGGACCCACCTGTC
GGCGCTGGTGCACCATAGCGTTATCCCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGTGTGGAGCAAGTATCAGAA
GGACAAAAAGAACTACAAAGAGCTGGAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCGCAAGGACGTCTGGCCCTT
TCTGCTTGGCCACTACAAGTTCGGCATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAGGTACCAGCAGGTGTTGGC
AGAGTGGAAGGCCTGCGAGGTGGTGGTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTTCTCCTCAGGCAGCAGCAT
CGACAGCCACGTGCAGCGCCTCATCCACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTATGGATCCAAAGTCAGTCT
CTTCTCTCACCTACCCCAGTACAGCAGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGATCCACCCAGCCATGGTGCG
ACTCGGCCTGCAGTACTCCCAGGGCCTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTTGCAGCAGGTGATTCAGGA
TTACACAACACCGCCTAATGAAGAACTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCTGACTCAGTGCCGTCCCCT
GTCAGCGAGCATGCACAACGCCATCAAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGAAGAGGAGGCCAAGTCAGA
ACTTCGAGCAGCCATTGATCGGTATGTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGCTTACCAGAAGATCAGTAA
TGGAGATGTGATCCTGGTATATGGATGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGGCCGGCGGTTTCGGGTGGT
AGTGGTGGACAGCCGGCCATGGCTGGAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGCCTCCTACCTGCTGATTCC
TGCAGCCTCCTATGTGCTCCCAGAGGTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTCTGTGATGTCACGGGTAGG
GACAGCACAGTTAGCCCTGGTGGCTCGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTTCTGTGAGCGTGTGCAGAC
TGATGCCTTTGTCTCTAATGAGCTAGATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCTGGCTAACTGGCAGAACCA
CGCATCCCTACGGTTGTTGAATCTAGTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGAGCTGGGGATGATCCCTTG
CAGTTCTGTACCTGTTGTTCTACGAGTCAAGAGCAGTGACCAGTGACGGGGGAAACACAGGGTTAATAAATGCCATACTCCCTACCCTCA

>81354_81354_9_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000574563_EIF2B4_chr2_27591330_ENST00000347454_length(amino acids)=1012AA_BP=655
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDMIEMQGFGPSLPAWHLE
PLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK
DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRT
KFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLR
ALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISR
FAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLAN
GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVI

--------------------------------------------------------------
>81354_81354_10_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000574563_EIF2B4_chr2_27591330_ENST00000445933_length(transcript)=3125nt_BP=2032nt
GAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATGGGCAGCGCAGAGGACGCAGT
CAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAGTTTGTGCATGAAGACAGCAG
CCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGCTTCCTGCGCAGTGACAAGAT
GGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAGCTGCAGCAACAAGCAGAGGG
CAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCCCTCAGCCCTCAGGCCTTGAA
ACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAACTGCAGCAAGTACTACGAGAA
GGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTGGAATACACTAAGCTCAAGAC
AGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCTACTCGCCAGGACTCCCCTGC
AAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCCTGTGCCCGCGAGTGTGTGGA
GTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAGGATATGGAGGCGGTCCCTGG
CTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGGACTCTGGGGGACTCCGAGCT
GGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCACCAGCAAAAGAGCGGTGGCAC
GCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTGTCCTTTCTGTCCTGTCTGGA
GAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTCCCCAAGCTACGGAAACGAAG
CAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATCTACCCCGGCCACAGGCACGA
GCACAACGCTGGTGACATGATCGAGATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCTGTGCAGTCAGGGCTCCTC
CTGCCTCTCCTGCTCCTCCAGCAGCTCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTTGCCGCTCAGGCTACTGTG
TGAGAGTATGAAGAGGCAGATCGTGTCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCACGGTGCGGACCCACCTGTC
GGCGCTGGTGCACCATAGCGTTATCCCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGTGTGGAGCAAGTATCAGAA
GGACAAAAAGAACTACAAAGAGCTGGAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCGCAAGGACGTCTGGCCCTT
TCTGCTTGGCCACTACAAGTTCGGCATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAGGTACCAGCAGGTGTTGGC
AGAGTGGAAGGCCTGCGAGGTGGTGGTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTTCTCCTCAGGCAGCAGCAT
CGACAGCCACGTGCAGCGCCTCATCCACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTATGGATCCAAAGTCAGTCT
CTTCTCTCACCTACCCCAGTACAGCAGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGATCCACCCAGCCATGGTGCG
ACTCGGCCTGCAGTACTCCCAGGGCCTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTTGCAGCAGGTGATTCAGGA
TTACACAACACCGCCTAATGAAGAACTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCTGACTCAGTGCCGTCCCCT
GTCAGCGAGCATGCACAACGCCATCAAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGAAGAGGAGGCCAAGTCAGA
ACTTCGAGCAGCCATTGATCGGTATGTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGCTTACCAGAAGATCAGTAA
TGGAGATGTGATCCTGGTATATGGATGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGGCCGGCGGTTTCGGGTGGT
AGTGGTGGACAGCCGGCCATGGCTGGAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGCCTCCTACCTGCTGATTCC
TGCAGCCTCCTATGTGCTCCCAGAGGTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTCTGTGATGTCACGGGTAGG
GACAGCACAGTTAGCCCTGGTGGCTCGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTTCTGTGAGCGTGTGCAGAC
TGATGCCTTTGTCTCTAATGAGCTAGATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCTGGCTAACTGGCAGAACCA
CGCATCCCTACGGTTGTTGAATCTAGTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGAGCTGGGGATGATCCCTTG

>81354_81354_10_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000574563_EIF2B4_chr2_27591330_ENST00000445933_length(amino acids)=1012AA_BP=655
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDMIEMQGFGPSLPAWHLE
PLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK
DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRT
KFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLR
ALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISR
FAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLAN
GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVI

--------------------------------------------------------------
>81354_81354_11_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000574563_EIF2B4_chr2_27591330_ENST00000451130_length(transcript)=3107nt_BP=2032nt
GAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATGGGCAGCGCAGAGGACGCAGT
CAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAGTTTGTGCATGAAGACAGCAG
CCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGCTTCCTGCGCAGTGACAAGAT
GGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAGCTGCAGCAACAAGCAGAGGG
CAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCCCTCAGCCCTCAGGCCTTGAA
ACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAACTGCAGCAAGTACTACGAGAA
GGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTGGAATACACTAAGCTCAAGAC
AGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCTACTCGCCAGGACTCCCCTGC
AAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCCTGTGCCCGCGAGTGTGTGGA
GTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAGGATATGGAGGCGGTCCCTGG
CTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGGACTCTGGGGGACTCCGAGCT
GGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCACCAGCAAAAGAGCGGTGGCAC
GCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTGTCCTTTCTGTCCTGTCTGGA
GAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTCCCCAAGCTACGGAAACGAAG
CAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATCTACCCCGGCCACAGGCACGA
GCACAACGCTGGTGACATGATCGAGATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCTGTGCAGTCAGGGCTCCTC
CTGCCTCTCCTGCTCCTCCAGCAGCTCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTTGCCGCTCAGGCTACTGTG
TGAGAGTATGAAGAGGCAGATCGTGTCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCACGGTGCGGACCCACCTGTC
GGCGCTGGTGCACCATAGCGTTATCCCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGTGTGGAGCAAGTATCAGAA
GGACAAAAAGAACTACAAAGAGCTGGAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCGCAAGGACGTCTGGCCCTT
TCTGCTTGGCCACTACAAGTTCGGCATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAGGTACCAGCAGGTGTTGGC
AGAGTGGAAGGCCTGCGAGGTGGTGGTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTTCTCCTCAGGCAGCAGCAT
CGACAGCCACGTGCAGCGCCTCATCCACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTATGGATCCAAAGTCAGTCT
CTTCTCTCACCTACCCCAGTACAGCAGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGATCCACCCAGCCATGGTGCG
ACTCGGCCTGCAGTACTCCCAGGGCCTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTTGCAGCAGGTGATTCAGGA
TTACACAACACCGCCTAATGAAGAACTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCTGACTCAGTGCCGTCCCCT
GTCAGCGAGCATGCACAACGCCATCAAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGAAGAGGAGGCCAAGTCAGA
ACTTCGAGCAGCCATTGATCGGTATGTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGCTTACCAGAAGATCAGTAA
TGGAGATGTGATCCTGGTATATGGATGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGGCCGGCGGTTTCGGGTGGT
AGTGGTGGACAGCCGGCCATGGCTGGAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGCCTCCTACCTGCTGATTCC
TGCAGCCTCCTATGTGCTCCCAGAGGTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTCTGTGATGTCACGGGTAGG
GACAGCACAGTTAGCCCTGGTGGCTCGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTTCTGTGAGCGTGTGCAGAC
TGATGCCTTTGTCTCTAATGAGCTAGATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCTGGCTAACTGGCAGAACCA
CGCATCCCTACGGTTGTTGAATCTAGTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGAGCTGGGGATGATCCCTTG

>81354_81354_11_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000574563_EIF2B4_chr2_27591330_ENST00000451130_length(amino acids)=1013AA_BP=655
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDMIEMQGFGPSLPAWHLE
PLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK
DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRT
KFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLR
ALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISR
FAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLAN
GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVI

--------------------------------------------------------------
>81354_81354_12_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000574563_EIF2B4_chr2_27591330_ENST00000493344_length(transcript)=3107nt_BP=2032nt
GAGAGGCGCGGAGGCGGCGAGGGCGCGGGGGCTCTGAGGACCGCTCGGCGCCGCCTCCTGCCACACCATGGGCAGCGCAGAGGACGCAGT
CAAAGAGAAACTGCTGTGGAACGTGAAGAAGGAGGTGAAGCAAATCATGGAGGAGGCTGTCACCAGGAAGTTTGTGCATGAAGACAGCAG
CCACATCATTGCTTTATGTGGTGCAGTGGAGGCTTGCCTCTTGCATCAGCTGAGACGCCGTGCCGCTGGCTTCCTGCGCAGTGACAAGAT
GGCAGCCCTGTTCACCAAGGTGGGGAAGACGTGCCCAGTGGCGGGGGAGATTTGCCACAAGGTACAGGAGCTGCAGCAACAAGCAGAGGG
CAGGAAACCCTCAGGGGTCAGCCAGGAGGCCCTGCGGAGACAGGGCTCAGCCAGCGGGAAGGCCCCGGCCCTCAGCCCTCAGGCCTTGAA
ACACGTATGGGTACGCACGGCGCTCATCGAGAAAGTTCTGGACAAGGTCGTGCAATACCTGGCGGAAAACTGCAGCAAGTACTACGAGAA
GGAGGCACTGCTGGCAGACCCTGTGTTCGGCCCGATCCTGGCCTCTCTTCTAGTGGGACCCTGTGCCTTGGAATACACTAAGCTCAAGAC
AGCCGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTCCAGCGGCACCGCATCCGGGGTCCACCTACTCGCCAGGACTCCCCTGC
AAAGCGCCCAGCCCTGGGGATCCGGAAACGGCACTCAAGCGGCAGCGCGTCGGAGGACAGGCTGGCTGCCTGTGCCCGCGAGTGTGTGGA
GTCCCTGCACCAGAACTCACGGACGCGGCTGCTCTATGGCAAGAACCACGTGCTGGTGCAGCCGAAGGAGGATATGGAGGCGGTCCCTGG
CTACCTCTCCCTGCACCAGTCTGCAGAGAGCCTGACTCTGAAGTGGACCCCCAACCAGCTCATGAATGGGACTCTGGGGGACTCCGAGCT
GGAAAAGAGCGTTTACTGGGACTATGCCCTCGTGGTGCCCTTCAGCCAGGTCGTGTGCATCCACTGCCACCAGCAAAAGAGCGGTGGCAC
GCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCGCCGCTGCATTTCCCACAGGGAGGACACCTGCTGTCCTTTCTGTCCTGTCTGGA
GAATGGGCTGCTGCCTCGGGGACAGCTAGAGCCCCCGCTGTGGACCCAGCAAGGGAAGGGGAAAGTGTTCCCCAAGCTACGGAAACGAAG
CAGCATTCGCTCCGTGGATATGGAGGAGATGGGCACGGGGCGGGCCACCGACTATGTGTTCCGGATCATCTACCCCGGCCACAGGCACGA
GCACAACGCTGGTGACATGATCGAGATGCAGGGCTTTGGGCCCAGCCTGCCAGCCTGGCACCTGGAGCCCCTGTGCAGTCAGGGCTCCTC
CTGCCTCTCCTGCTCCTCCAGCAGCTCCCCACATGCAACCCCCAGCCACTGTAGCTGCATCCCCGACCGGTTGCCGCTCAGGCTACTGTG
TGAGAGTATGAAGAGGCAGATCGTGTCCCGGGCCTTCTACGGCTGGCTGGCACACTGCCGCCACCTGTCCACGGTGCGGACCCACCTGTC
GGCGCTGGTGCACCATAGCGTTATCCCACCTGACCGGCCCCCGGGGGCCTCCGCGGGCCTCACCAAGGACGTGTGGAGCAAGTATCAGAA
GGACAAAAAGAACTACAAAGAGCTGGAGCTGCTGCGGCAAGTTTACTACGGAGGCATAGAGCACGAGATCCGCAAGGACGTCTGGCCCTT
TCTGCTTGGCCACTACAAGTTCGGCATGAGCAAGAAGGAGATGGAGCAGGTGGACGCAGTGGTGGCAGCAAGGTACCAGCAGGTGTTGGC
AGAGTGGAAGGCCTGCGAGGTGGTGGTGAGGCAGCGGGAGCGGGAGGCCCACCCAGCCACACGCACCAAGTTCTCCTCAGGCAGCAGCAT
CGACAGCCACGTGCAGCGCCTCATCCACCGAGACTCCACCATCAGCAACGATGTTCCTACACGAAAGGATTATGGATCCAAAGTCAGTCT
CTTCTCTCACCTACCCCAGTACAGCAGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCCTCTGTGATCCACCCAGCCATGGTGCG
ACTCGGCCTGCAGTACTCCCAGGGCCTGGTCAGTGGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTTGCAGCAGGTGATTCAGGA
TTACACAACACCGCCTAATGAAGAACTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATGAGCTTCCTGACTCAGTGCCGTCCCCT
GTCAGCGAGCATGCACAACGCCATCAAGTTCCTTAACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGAAGAGGAGGCCAAGTCAGA
ACTTCGAGCAGCCATTGATCGGTATGTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCACGCTTTGCTTACCAGAAGATCAGTAA
TGGAGATGTGATCCTGGTATATGGATGCTCATCTCTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGGCCGGCGGTTTCGGGTGGT
AGTGGTGGACAGCCGGCCATGGCTGGAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGTGTCCCAGCCTCCTACCTGCTGATTCC
TGCAGCCTCCTATGTGCTCCCAGAGGTTTCCAAGGTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTCTGTGATGTCACGGGTAGG
GACAGCACAGTTAGCCCTGGTGGCTCGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACATACAAGTTCTGTGAGCGTGTGCAGAC
TGATGCCTTTGTCTCTAATGAGCTAGATGACCCTGATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCTGGCTAACTGGCAGAACCA
CGCATCCCTACGGTTGTTGAATCTAGTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTGATCACGGAGCTGGGGATGATCCCTTG

>81354_81354_12_SGSM2-EIF2B4_SGSM2_chr17_2276807_ENST00000574563_EIF2B4_chr2_27591330_ENST00000493344_length(amino acids)=1013AA_BP=655
MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEICHKVQ
ELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA
LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNSRTRLLYGKNHVLVQPK
EDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL
LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDMIEMQGFGPSLPAWHLE
PLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK
DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPATRT
KFSSGSSIDSHVQRLIHRDSTISNDVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLR
ALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISR
FAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLAN
GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SGSM2-EIF2B4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SGSM2-EIF2B4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SGSM2-EIF2B4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource