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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SH3GL1-MUM1 (FusionGDB2 ID:81455)

Fusion Gene Summary for SH3GL1-MUM1

check button Fusion gene summary
Fusion gene informationFusion gene name: SH3GL1-MUM1
Fusion gene ID: 81455
HgeneTgene
Gene symbol

SH3GL1

MUM1

Gene ID

6455

84939

Gene nameSH3 domain containing GRB2 like 1, endophilin A2PWWP domain containing 3A, DNA repair factor
SynonymsCNSA1|EEN|SH3D2B|SH3P8EXPAND1|HSPC211|MUM-1|MUM1
Cytomap

19p13.3

19p13.3

Type of geneprotein-codingprotein-coding
Descriptionendophilin-A2EEN fusion partner of MLLSH3 domain protein 2BSH3 domain-containing GRB2-like protein 1SH3-containing Grb-2-like 1 proteinSH3-domain GRB2-like 1endophilin-2extra 11-19 leukemia fusionextra eleven-nineteen leukemia fusion gene proteinPWWP domain-containing DNA repair factor 3APWWP domain-containing protein MUM1melanoma associated antigen (mutated) 1melanoma ubiquitous mutated proteinmutated melanoma-associated antigen 1protein expandere
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000269886, ENST00000417295, 
ENST00000598564, 		ENST00000311401, 
ENST00000344663, ENST00000415183, 
ENST00000591806, ENST00000591453, 
Fusion gene scores* DoF score18 X 9 X 12=194410 X 10 X 4=400
# samples 2210
** MAII scorelog2(22/1944*10)=-3.14345279008112
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/400*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SH3GL1 [Title/Abstract] AND MUM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSH3GL1(4400321)-MUM1(1357008), # samples:1
SH3GL1(4400321)-MUM1(1356323), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SH3GL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MUM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AN-A04A-01ASH3GL1chr19

4400321

-MUM1chr19

1356323

+
ChimerDB4BRCATCGA-AN-A04A-01ASH3GL1chr19

4400321

-MUM1chr19

1357008

+


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Fusion Gene ORF analysis for SH3GL1-MUM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000269886ENST00000311401SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-5UTRENST00000269886ENST00000311401SH3GL1chr19

4400321

-MUM1chr19

1357008

+
5CDS-5UTRENST00000269886ENST00000344663SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-5UTRENST00000269886ENST00000415183SH3GL1chr19

4400321

-MUM1chr19

1357008

+
5CDS-5UTRENST00000269886ENST00000591806SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-5UTRENST00000417295ENST00000311401SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-5UTRENST00000417295ENST00000311401SH3GL1chr19

4400321

-MUM1chr19

1357008

+
5CDS-5UTRENST00000417295ENST00000344663SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-5UTRENST00000417295ENST00000415183SH3GL1chr19

4400321

-MUM1chr19

1357008

+
5CDS-5UTRENST00000417295ENST00000591806SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-5UTRENST00000598564ENST00000311401SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-5UTRENST00000598564ENST00000311401SH3GL1chr19

4400321

-MUM1chr19

1357008

+
5CDS-5UTRENST00000598564ENST00000344663SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-5UTRENST00000598564ENST00000415183SH3GL1chr19

4400321

-MUM1chr19

1357008

+
5CDS-5UTRENST00000598564ENST00000591806SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-intronENST00000269886ENST00000415183SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-intronENST00000269886ENST00000591453SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-intronENST00000269886ENST00000591453SH3GL1chr19

4400321

-MUM1chr19

1357008

+
5CDS-intronENST00000417295ENST00000415183SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-intronENST00000417295ENST00000591453SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-intronENST00000417295ENST00000591453SH3GL1chr19

4400321

-MUM1chr19

1357008

+
5CDS-intronENST00000598564ENST00000415183SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-intronENST00000598564ENST00000591453SH3GL1chr19

4400321

-MUM1chr19

1356323

+
5CDS-intronENST00000598564ENST00000591453SH3GL1chr19

4400321

-MUM1chr19

1357008

+
In-frameENST00000269886ENST00000344663SH3GL1chr19

4400321

-MUM1chr19

1357008

+
In-frameENST00000269886ENST00000591806SH3GL1chr19

4400321

-MUM1chr19

1357008

+
In-frameENST00000417295ENST00000344663SH3GL1chr19

4400321

-MUM1chr19

1357008

+
In-frameENST00000417295ENST00000591806SH3GL1chr19

4400321

-MUM1chr19

1357008

+
In-frameENST00000598564ENST00000344663SH3GL1chr19

4400321

-MUM1chr19

1357008

+
In-frameENST00000598564ENST00000591806SH3GL1chr19

4400321

-MUM1chr19

1357008

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000269886SH3GL1chr194400321-ENST00000344663MUM1chr191357008+41552241792299706
ENST00000269886SH3GL1chr194400321-ENST00000591806MUM1chr191357008+41542241792299706
ENST00000598564SH3GL1chr194400321-ENST00000344663MUM1chr191357008+402695502170706
ENST00000598564SH3GL1chr194400321-ENST00000591806MUM1chr191357008+402595502170706
ENST00000417295SH3GL1chr194400321-ENST00000344663MUM1chr191357008+41332021572277706
ENST00000417295SH3GL1chr194400321-ENST00000591806MUM1chr191357008+41322021572277706

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000269886ENST00000344663SH3GL1chr194400321-MUM1chr191357008+0.0050854630.99491453
ENST00000269886ENST00000591806SH3GL1chr194400321-MUM1chr191357008+0.0050661980.9949338
ENST00000598564ENST00000344663SH3GL1chr194400321-MUM1chr191357008+0.0048361640.9951638
ENST00000598564ENST00000591806SH3GL1chr194400321-MUM1chr191357008+0.0048190150.99518096
ENST00000417295ENST00000344663SH3GL1chr194400321-MUM1chr191357008+0.0051862580.9948138
ENST00000417295ENST00000591806SH3GL1chr194400321-MUM1chr191357008+0.005167790.99483216

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Fusion Genomic Features for SH3GL1-MUM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SH3GL1chr194400320-MUM1chr191356322+0.0001466170.9998534
SH3GL1chr194400320-MUM1chr191357007+2.84E-060.99999714
SH3GL1chr194400320-MUM1chr191356322+0.0001466170.9998534
SH3GL1chr194400320-MUM1chr191357007+2.84E-060.99999714

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SH3GL1-MUM1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:4400321/chr19:1357008)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMUM1chr19:4400321chr19:1357008ENST00000311401014273_3490643.0Compositional biasNote=Pro-rich
TgeneMUM1chr19:4400321chr19:1357008ENST00000311401014411_4720643.0DomainNote=PWWP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000269886-110145_25015369.0Coiled coilOntology_term=ECO:0000255
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000417295-19145_25015321.0Coiled coilOntology_term=ECO:0000255
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000598564-110145_25015305.0Coiled coilOntology_term=ECO:0000255
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000269886-11018_24915369.0DomainBAR
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000269886-110306_36515369.0DomainSH3
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000417295-1918_24915321.0DomainBAR
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000417295-19306_36515321.0DomainSH3
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000598564-11018_24915305.0DomainBAR
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000598564-110306_36515305.0DomainSH3
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000269886-1101_2115369.0RegionMembrane-binding amphipathic helix
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000269886-11060_8715369.0RegionRequired for dimerization upon membrane association
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000417295-191_2115321.0RegionMembrane-binding amphipathic helix
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000417295-1960_8715321.0RegionRequired for dimerization upon membrane association
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000598564-1101_2115305.0RegionMembrane-binding amphipathic helix
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000598564-11060_8715305.0RegionRequired for dimerization upon membrane association


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Fusion Gene Sequence for SH3GL1-MUM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>81455_81455_1_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000269886_MUM1_chr19_1357008_ENST00000344663_length(transcript)=4155nt_BP=224nt
AATATCCTGGCCGCGCGGGCGCGCGAGCGGCTGAGGCGGCGCCGGGGCGGGCGCGGAGCTGGCAAGCGGGTGGCGGAGGCGGCGCCGACG
GGGACTGCTGAGGCGCGCAGAGGGTCGGCGGCGCCCGGGAGCCTGTCGCTGGCGCGGTCCGGGCGGGAGGCTCGGCGGCGGGCGGCAGCA
TGTCGGTGGCGGGGCTGAAGAAGCAGTTCTACAAGGCGAGCCAGGTTTTGGCCCGAACCGCGACTTCAACAAAAAATAAGAGAAGAAAGG
AATATTTTCTAGCTGTGCAAATCCTCTCTCTAGAGGAAAAAATTAAGGTGAAAAGCACTGAAGTTGAGATCCTAGAGAAGTCTCAAATTG
AAGCCATTGCTTCCTCGTTAGCCTCACAGAATGAGGTTCCTGCGGCACCCCTGGAAGAACTGGCCTACAGACGGTCGCTTCGCGTGGCTC
TGGACGTTCTGAGCGAGGGCTCGATTTGGAGTCAAGAAAGCTCTGCAGGGACAGGTAGAGCTGACCGGTCTCTGCGAGGGAAGCCCATGG
AGCATGTCTCCTCGCCCTGTGATTCGAACTCCTCATCTCTTCCCCGCGGAGACGTGTTGGGCAGTTCCAGACCTCACAGGAGGAGGCCAT
GTGTGCAACAAAGCCTGTCAAGTTCGTTCACTTGTGAAAAGGACCCCGAGTGCAAAGTGGACCACAAGAAGGGGCTCAGGAAAAGTGAAA
ACCCAAGAGGCCCGTTGGTCCTCCCAGCTGGAGGTGGTGCCCAAGATGAGAGTGGGTCCAGAATCCACCACAAAAATTGGACTCTTGCAA
GTAAGAGGGGAGGAAACTCAGCGCAGAAGGCTAGCTTGTGCCTGAATGGATCTTCCCTTTCAGAGGACGACACGGAGAGAGACATGGGGA
GCAAAGGAGGCAGCTGGGCAGCCCCGTCCTTGCCCTCCGGGGTCAGGGAGGACGATCCCTGTGCCAACGCTGAGGGACACGACCCCGGTC
TGCCGTTGGGCAGCCTCACTGCGCCCCCAGCCCCTGAGCCCTCGGCCTGCTCAGAGCCTGGAGAATGCCCTGCGAAAAAGAGGCCGCGCC
TGGATGGCAGCCAAAGGCCGCCTGCCGTGCAGCTGGAGCCCATGGCAGCAGGGGCCGCACCATCCCCCGGGCCGGGGCCAGGGCCCAGAG
AGTCTGTGACCCCGCGCAGCACCGCCAGGCTGGGCCCGCCTCCCTCCCACGCCTCTGCGGATGCAACCAGATGTCTTCCTTGCCCGGATT
CCCAGAAGCTGGAGAAAGAGTGCCAGTCTTCCGAAGAGTCCATGGGGTCTAATTCCATGCGTTCTATCCTGGAGGAAGACGAGGAAGACG
AGGAGCCACCAAGAGTCCTTTTATACCACGAACCACGTTCGTTTGAAGTAGGAATGCTAGTCTGGCATAAACATAAAAAATACCCCTTCT
GGCCAGCAGTGGTCAAAAGCGTCAGGCAGAGAGATAAGAAAGCAAGTGTGCTATACATCGAAGGACACATGAACCCGAAAATGAAAGGTT
TCACAGTGTCTCTTAAAAGTTTAAAGCACTTTGATTGTAAAGAGAAACAGACGCTTCTGAATCAAGCCAGGGAGGACTTCAACCAGGACA
TCGGCTGGTGTGTCTCCCTCATCACCGACTACAGGGTCCGGTTAGGCTGCGGGTCTTTTGCTGGCTCTTTCCTGGAATATTACGCGGCTG
ATATAAGCTATCCTGTCCGAAAATCCATCCAGCAGGACGTCTTGGGGACCAAGCTTCCTCAACTGAGCAAGGGGAGCCCCGAGGAGCCCG
TGGTGGGGTGCCCCCTGGGGCAGAGGCAGCCCTGCCGGAAAATGCTCCCCGACCGCTCGCGGGCCGCCCGGGACCGGGCCAACCAGAAGC
TGGTGGAGTACATTGTGAAGGCCAAGGGCGCGGAGAGCCACCTGCGGGCCATCCTAAAGAGCAGGAAGCCATCTCGCTGGCTGCAGACCT
TCCTGAGCTCCAGCCAGTACGTGACCTGTGTGGAGACCTACCTGGAGGATGAGGGGCAGCTGGACCTGGTGGTGAAGTACCTGCAGGGCG
TCTACCAGGAGGTGGGGGCCAAGGTGCTCCAGCGCACCAACGGCGACCGGATCCGGTTCATTCTGGACGTGCTTCTGCCCGAGGCCATCA
TCTGTGCGATCTCTGCGGTGGACGAGGTGGACTACAAGACGGCTGAGGAGAAGTACATCAAGGGGCCTTCGCTGAGCTACCGGGAAAAAG
AAATATTTGACAACCAGCTCCTTGAAGAGCGGAACCGGCGCCGTCGGTGAGGGAGCAGCCGGCTGTGCTGTCAGCGGGGCCTGGCGGTGG
AAGCGCCTCCAGTGTGCATGAGCGTGTCTGAAGATGGGGGGCTCAGGGGGCACGTTTGCGTTTGGACCTGTCTGTGCGTTCTCCTGCGTG
GCAGTCCTGATTTCCATGCTTCTGGAGAATCCATTTCGTTAACACTGAAAGCCAGTTCTCTTTTCCTGGCAGTTTTTTTCATTTTATTTT
TGGCATTTTTTACAAGATACCGTTCGGGAAAGGCTTTTGAAAGGACGGAAGCGTATTCACTGTGCGCCAGTACTCCTGGCTGTGCTGTGG
TTTCTCCCGACGTGCACATCGATCTCGTATGTGTGGCATCTGATATTAAACGGGAGGTTTTAAGAAGCGTCTGCCGTGATCATGGAGCTT
CGGAAGCGGGAATGGTTCTTCCGGGTTTGCTGTTTTGTCTGTTTCCCCCTTGTGTGGTTTCCGCCTGCGACAGTTCCAGAATTTGCTCTC
CCACTCAGTGTGCTCTGCAGCTGTGAGGAAACAGCCTTCGTTAGAGGCGGGAGCAGAGACGAGCCGCTGCTCTGTGTCGTGTTTGCTGTG
GCCGCAGGGAGAGGAGCAGGACACGCACCTTTCCAGGGGCCTCTGTGTCCCGCACTGTGTGTGAGTGGACCGCAGCGCGCAGCCACATGC
CCTGGCTGCCATGGGCCAGACCGCCTCCACCTCCCCCGCCCGCCTGGCCTGTCCTGAGTGCATTTCCCTGCACTGTGTCGTCACTGCACA
GCCAGTCACCGCGGTCTCAGTCATCGGCGCGGATGGCTATGCTGGGGTCCCAGGGTGGCCGCAGCAGTCAGGGTCACTGTGGGAGCCCTG
GGGTGGAGTGACAAACCGCATTGTCCTGTGCCCGCCATGGCAGAAGCGCAGCCTTTGTATGGAGGCCCAACCGCGCTCCCGTCTGGAGAA
GCGGCTTCCGGGGTGTGGCTGCCGGGTCGGCTCTGGTCCACAGCACGGTGCCGGGGCTGCAGGTTGTTGAGGGCTGTGACTCCGTGGGGC
TCAGCCAGGCTCCAGCAGGGTCAGACGTGCTGTTAAGAGCAAAGCCACAGACGATGACTTGTCCATTCTCAGTGGATGCTCCAGGCTGTG
CCTACACAGCAGTGCTGGTGACATGTCCAGGGTTCCAGGGCCCGGTGGCCTGGGAGCTGCTTTCTCCCCACTGGCTGGGCTGCATCTGGC
CCTGGCTGGAGGCCTTGCTTTGAGGGGCTGTGACCCTCTTCCCCCAGGCCCTCCCCAGCCGACGACAGCCACCGGAGAGGAGATCGGAAC
ACGATTGTCTCAGATGCAGGGCGCTGTGCGGGACGAAGCCGCAAGGACTCTCGTATCGGGCCCTTGGGACTCGGGAGGTGCCAGAGGCGG
CGGCTGCTCTGGACCTCGGTGTTCACTGACCTTTGTTTCACTTGCCTCTGCTCGACTCCGAGAGCAGGAAACCCGGCCGTGGCCTGGCAG
CTCCGCCTCCCATGCCCGCACGCTGGGGTCTGTCTTGTCTGGAGCAGTGGGGCACACCCCGGAGGAGGCGGGGGTCAGGGCTGTCGGCCT
TGGCCCCCTGCTGGTCGCTGTTTCGGGGACTCGGGGCGGCCAGTACCACCGCCTGAGGCGGGGCTCAGCAGCGTTGCATGTACGGGCCTC
GTACTGCCTCATGGAAAATCCTCCGGAGCCGCCCTCCATTGTGGGTTCCTGAGAGTAGGACACATTGCCATGGTTTTGTGGGAATCACGC
GCCCCTGATGGAACTTTTCTGCTGTTGTGAAGTACTTTTATCCATTTGCTTCTCTGCTGACCTTGCCAAGTTGTTCGAGGTGGAATTAAA

>81455_81455_1_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000269886_MUM1_chr19_1357008_ENST00000344663_length(amino acids)=706AA_BP=15
MSVAGLKKQFYKASQVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVA
LDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSE
NPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPG
LPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPD
SQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKG
FTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKGSPEEP
VVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQG

--------------------------------------------------------------
>81455_81455_2_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000269886_MUM1_chr19_1357008_ENST00000591806_length(transcript)=4154nt_BP=224nt
AATATCCTGGCCGCGCGGGCGCGCGAGCGGCTGAGGCGGCGCCGGGGCGGGCGCGGAGCTGGCAAGCGGGTGGCGGAGGCGGCGCCGACG
GGGACTGCTGAGGCGCGCAGAGGGTCGGCGGCGCCCGGGAGCCTGTCGCTGGCGCGGTCCGGGCGGGAGGCTCGGCGGCGGGCGGCAGCA
TGTCGGTGGCGGGGCTGAAGAAGCAGTTCTACAAGGCGAGCCAGGTTTTGGCCCGAACCGCGACTTCAACAAAAAATAAGAGAAGAAAGG
AATATTTTCTAGCTGTGCAAATCCTCTCTCTAGAGGAAAAAATTAAGGTGAAAAGCACTGAAGTTGAGATCCTAGAGAAGTCTCAAATTG
AAGCCATTGCTTCCTCGTTAGCCTCACAGAATGAGGTTCCTGCGGCACCCCTGGAAGAACTGGCCTACAGACGGTCGCTTCGCGTGGCTC
TGGACGTTCTGAGCGAGGGCTCGATTTGGAGTCAAGAAAGCTCTGCAGGGACAGGTAGAGCTGACCGGTCTCTGCGAGGGAAGCCCATGG
AGCATGTCTCCTCGCCCTGTGATTCGAACTCCTCATCTCTTCCCCGCGGAGACGTGTTGGGCAGTTCCAGACCTCACAGGAGGAGGCCAT
GTGTGCAACAAAGCCTGTCAAGTTCGTTCACTTGTGAAAAGGACCCCGAGTGCAAAGTGGACCACAAGAAGGGGCTCAGGAAAAGTGAAA
ACCCAAGAGGCCCGTTGGTCCTCCCAGCTGGAGGTGGTGCCCAAGATGAGAGTGGGTCCAGAATCCACCACAAAAATTGGACTCTTGCAA
GTAAGAGGGGAGGAAACTCAGCGCAGAAGGCTAGCTTGTGCCTGAATGGATCTTCCCTTTCAGAGGACGACACGGAGAGAGACATGGGGA
GCAAAGGAGGCAGCTGGGCAGCCCCGTCCTTGCCCTCCGGGGTCAGGGAGGACGATCCCTGTGCCAACGCTGAGGGACACGACCCCGGTC
TGCCGTTGGGCAGCCTCACTGCGCCCCCAGCCCCTGAGCCCTCGGCCTGCTCAGAGCCTGGAGAATGCCCTGCGAAAAAGAGGCCGCGCC
TGGATGGCAGCCAAAGGCCGCCTGCCGTGCAGCTGGAGCCCATGGCAGCAGGGGCCGCACCATCCCCCGGGCCGGGGCCAGGGCCCAGAG
AGTCTGTGACCCCGCGCAGCACCGCCAGGCTGGGCCCGCCTCCCTCCCACGCCTCTGCGGATGCAACCAGATGTCTTCCTTGCCCGGATT
CCCAGAAGCTGGAGAAAGAGTGCCAGTCTTCCGAAGAGTCCATGGGGTCTAATTCCATGCGTTCTATCCTGGAGGAAGACGAGGAAGACG
AGGAGCCACCAAGAGTCCTTTTATACCACGAACCACGTTCGTTTGAAGTAGGAATGCTAGTCTGGCATAAACATAAAAAATACCCCTTCT
GGCCAGCAGTGGTCAAAAGCGTCAGGCAGAGAGATAAGAAAGCAAGTGTGCTATACATCGAAGGACACATGAACCCGAAAATGAAAGGTT
TCACAGTGTCTCTTAAAAGTTTAAAGCACTTTGATTGTAAAGAGAAACAGACGCTTCTGAATCAAGCCAGGGAGGACTTCAACCAGGACA
TCGGCTGGTGTGTCTCCCTCATCACCGACTACAGGGTCCGGTTAGGCTGCGGGTCTTTTGCTGGCTCTTTCCTGGAATATTACGCGGCTG
ATATAAGCTATCCTGTCCGAAAATCCATCCAGCAGGACGTCTTGGGGACCAAGCTTCCTCAACTGAGCAAGGGGAGCCCCGAGGAGCCCG
TGGTGGGGTGCCCCCTGGGGCAGAGGCAGCCCTGCCGGAAAATGCTCCCCGACCGCTCGCGGGCCGCCCGGGACCGGGCCAACCAGAAGC
TGGTGGAGTACATTGTGAAGGCCAAGGGCGCGGAGAGCCACCTGCGGGCCATCCTAAAGAGCAGGAAGCCATCTCGCTGGCTGCAGACCT
TCCTGAGCTCCAGCCAGTACGTGACCTGTGTGGAGACCTACCTGGAGGATGAGGGGCAGCTGGACCTGGTGGTGAAGTACCTGCAGGGCG
TCTACCAGGAGGTGGGGGCCAAGGTGCTCCAGCGCACCAACGGCGACCGGATCCGGTTCATTCTGGACGTGCTTCTGCCCGAGGCCATCA
TCTGTGCGATCTCTGCGGTGGACGAGGTGGACTACAAGACGGCTGAGGAGAAGTACATCAAGGGGCCTTCGCTGAGCTACCGGGAAAAAG
AAATATTTGACAACCAGCTCCTTGAAGAGCGGAACCGGCGCCGTCGGTGAGGGAGCAGCCGGCTGTGCTGTCAGCGGGGCCTGGCGGTGG
AAGCGCCTCCAGTGTGCATGAGCGTGTCTGAAGATGGGGGGCTCAGGGGGCACGTTTGCGTTTGGACCTGTCTGTGCGTTCTCCTGCGTG
GCAGTCCTGATTTCCATGCTTCTGGAGAATCCATTTCGTTAACACTGAAAGCCAGTTCTCTTTTCCTGGCAGTTTTTTTCATTTTATTTT
TGGCATTTTTTACAAGATACCGTTCGGGAAAGGCTTTTGAAAGGACGGAAGCGTATTCACTGTGCGCCAGTACTCCTGGCTGTGCTGTGG
TTTCTCCCGACGTGCACATCGATCTCGTATGTGTGGCATCTGATATTAAACGGGAGGTTTTAAGAAGCGTCTGCCGTGATCATGGAGCTT
CGGAAGCGGGAATGGTTCTTCCGGGTTTGCTGTTTTGTCTGTTTCCCCCTTGTGTGGTTTCCGCCTGCGACAGTTCCAGAATTTGCTCTC
CCACTCAGTGTGCTCTGCAGCTGTGAGGAAACAGCCTTCGTTAGAGGCGGGAGCAGAGACGAGCCGCTGCTCTGTGTCGTGTTTGCTGTG
GCCGCAGGGAGAGGAGCAGGACACGCACCTTTCCAGGGGCCTCTGTGTCCCGCACTGTGTGTGAGTGGACCGCAGCGCGCAGCCACATGC
CCTGGCTGCCATGGGCCAGACCGCCTCCACCTCCCCCGCCCGCCTGGCCTGTCCTGAGTGCATTTCCCTGCACTGTGTCGTCACTGCACA
GCCAGTCACCGCGGTCTCAGTCATCGGCGCGGATGGCTATGCTGGGGTCCCAGGGTGGCCGCAGCAGTCAGGGTCACTGTGGGAGCCCTG
GGGTGGAGTGACAAACCGCATTGTCCTGTGCCCGCCATGGCAGAAGCGCAGCCTTTGTATGGAGGCCCAACCGCGCTCCCGTCTGGAGAA
GCGGCTTCCGGGGTGTGGCTGCCGGGTCGGCTCTGGTCCACAGCACGGTGCCGGGGCTGCAGGTTGTTGAGGGCTGTGACTCCGTGGGGC
TCAGCCAGGCTCCAGCAGGGTCAGACGTGCTGTTAAGAGCAAAGCCACAGACGATGACTTGTCCATTCTCAGTGGATGCTCCAGGCTGTG
CCTACACAGCAGTGCTGGTGACATGTCCAGGGTTCCAGGGCCCGGTGGCCTGGGAGCTGCTTTCTCCCCACTGGCTGGGCTGCATCTGGC
CCTGGCTGGAGGCCTTGCTTTGAGGGGCTGTGACCCTCTTCCCCCAGGCCCTCCCCAGCCGACGACAGCCACCGGAGAGGAGATCGGAAC
ACGATTGTCTCAGATGCAGGGCGCTGTGCGGGACGAAGCCGCAAGGACTCTCGTATCGGGCCCTTGGGACTCGGGAGGTGCCAGAGGCGG
CGGCTGCTCTGGACCTCGGTGTTCACTGACCTTTGTTTCACTTGCCTCTGCTCGACTCCGAGAGCAGGAAACCCGGCCGTGGCCTGGCAG
CTCCGCCTCCCATGCCCGCACGCTGGGGTCTGTCTTGTCTGGAGCAGTGGGGCACACCCCGGAGGAGGCGGGGGTCAGGGCTGTCGGCCT
TGGCCCCCTGCTGGTCGCTGTTTCGGGGACTCGGGGCGGCCAGTACCACCGCCTGAGGCGGGGCTCAGCAGCGTTGCATGTACGGGCCTC
GTACTGCCTCATGGAAAATCCTCCGGAGCCGCCCTCCATTGTGGGTTCCTGAGAGTAGGACACATTGCCATGGTTTTGTGGGAATCACGC
GCCCCTGATGGAACTTTTCTGCTGTTGTGAAGTACTTTTATCCATTTGCTTCTCTGCTGACCTTGCCAAGTTGTTCGAGGTGGAATTAAA

>81455_81455_2_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000269886_MUM1_chr19_1357008_ENST00000591806_length(amino acids)=706AA_BP=15
MSVAGLKKQFYKASQVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVA
LDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSE
NPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPG
LPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPD
SQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKG
FTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKGSPEEP
VVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQG

--------------------------------------------------------------
>81455_81455_3_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000417295_MUM1_chr19_1357008_ENST00000344663_length(transcript)=4133nt_BP=202nt
GCGAGCGGCTGAGGCGGCGCCGGGGCGGGCGCGGAGCTGGCAAGCGGGTGGCGGAGGCGGCGCCGACGGGGACTGCTGAGGCGCGCAGAG
GGTCGGCGGCGCCCGGGAGCCTGTCGCTGGCGCGGTCCGGGCGGGAGGCTCGGCGGCGGGCGGCAGCATGTCGGTGGCGGGGCTGAAGAA
GCAGTTCTACAAGGCGAGCCAGGTTTTGGCCCGAACCGCGACTTCAACAAAAAATAAGAGAAGAAAGGAATATTTTCTAGCTGTGCAAAT
CCTCTCTCTAGAGGAAAAAATTAAGGTGAAAAGCACTGAAGTTGAGATCCTAGAGAAGTCTCAAATTGAAGCCATTGCTTCCTCGTTAGC
CTCACAGAATGAGGTTCCTGCGGCACCCCTGGAAGAACTGGCCTACAGACGGTCGCTTCGCGTGGCTCTGGACGTTCTGAGCGAGGGCTC
GATTTGGAGTCAAGAAAGCTCTGCAGGGACAGGTAGAGCTGACCGGTCTCTGCGAGGGAAGCCCATGGAGCATGTCTCCTCGCCCTGTGA
TTCGAACTCCTCATCTCTTCCCCGCGGAGACGTGTTGGGCAGTTCCAGACCTCACAGGAGGAGGCCATGTGTGCAACAAAGCCTGTCAAG
TTCGTTCACTTGTGAAAAGGACCCCGAGTGCAAAGTGGACCACAAGAAGGGGCTCAGGAAAAGTGAAAACCCAAGAGGCCCGTTGGTCCT
CCCAGCTGGAGGTGGTGCCCAAGATGAGAGTGGGTCCAGAATCCACCACAAAAATTGGACTCTTGCAAGTAAGAGGGGAGGAAACTCAGC
GCAGAAGGCTAGCTTGTGCCTGAATGGATCTTCCCTTTCAGAGGACGACACGGAGAGAGACATGGGGAGCAAAGGAGGCAGCTGGGCAGC
CCCGTCCTTGCCCTCCGGGGTCAGGGAGGACGATCCCTGTGCCAACGCTGAGGGACACGACCCCGGTCTGCCGTTGGGCAGCCTCACTGC
GCCCCCAGCCCCTGAGCCCTCGGCCTGCTCAGAGCCTGGAGAATGCCCTGCGAAAAAGAGGCCGCGCCTGGATGGCAGCCAAAGGCCGCC
TGCCGTGCAGCTGGAGCCCATGGCAGCAGGGGCCGCACCATCCCCCGGGCCGGGGCCAGGGCCCAGAGAGTCTGTGACCCCGCGCAGCAC
CGCCAGGCTGGGCCCGCCTCCCTCCCACGCCTCTGCGGATGCAACCAGATGTCTTCCTTGCCCGGATTCCCAGAAGCTGGAGAAAGAGTG
CCAGTCTTCCGAAGAGTCCATGGGGTCTAATTCCATGCGTTCTATCCTGGAGGAAGACGAGGAAGACGAGGAGCCACCAAGAGTCCTTTT
ATACCACGAACCACGTTCGTTTGAAGTAGGAATGCTAGTCTGGCATAAACATAAAAAATACCCCTTCTGGCCAGCAGTGGTCAAAAGCGT
CAGGCAGAGAGATAAGAAAGCAAGTGTGCTATACATCGAAGGACACATGAACCCGAAAATGAAAGGTTTCACAGTGTCTCTTAAAAGTTT
AAAGCACTTTGATTGTAAAGAGAAACAGACGCTTCTGAATCAAGCCAGGGAGGACTTCAACCAGGACATCGGCTGGTGTGTCTCCCTCAT
CACCGACTACAGGGTCCGGTTAGGCTGCGGGTCTTTTGCTGGCTCTTTCCTGGAATATTACGCGGCTGATATAAGCTATCCTGTCCGAAA
ATCCATCCAGCAGGACGTCTTGGGGACCAAGCTTCCTCAACTGAGCAAGGGGAGCCCCGAGGAGCCCGTGGTGGGGTGCCCCCTGGGGCA
GAGGCAGCCCTGCCGGAAAATGCTCCCCGACCGCTCGCGGGCCGCCCGGGACCGGGCCAACCAGAAGCTGGTGGAGTACATTGTGAAGGC
CAAGGGCGCGGAGAGCCACCTGCGGGCCATCCTAAAGAGCAGGAAGCCATCTCGCTGGCTGCAGACCTTCCTGAGCTCCAGCCAGTACGT
GACCTGTGTGGAGACCTACCTGGAGGATGAGGGGCAGCTGGACCTGGTGGTGAAGTACCTGCAGGGCGTCTACCAGGAGGTGGGGGCCAA
GGTGCTCCAGCGCACCAACGGCGACCGGATCCGGTTCATTCTGGACGTGCTTCTGCCCGAGGCCATCATCTGTGCGATCTCTGCGGTGGA
CGAGGTGGACTACAAGACGGCTGAGGAGAAGTACATCAAGGGGCCTTCGCTGAGCTACCGGGAAAAAGAAATATTTGACAACCAGCTCCT
TGAAGAGCGGAACCGGCGCCGTCGGTGAGGGAGCAGCCGGCTGTGCTGTCAGCGGGGCCTGGCGGTGGAAGCGCCTCCAGTGTGCATGAG
CGTGTCTGAAGATGGGGGGCTCAGGGGGCACGTTTGCGTTTGGACCTGTCTGTGCGTTCTCCTGCGTGGCAGTCCTGATTTCCATGCTTC
TGGAGAATCCATTTCGTTAACACTGAAAGCCAGTTCTCTTTTCCTGGCAGTTTTTTTCATTTTATTTTTGGCATTTTTTACAAGATACCG
TTCGGGAAAGGCTTTTGAAAGGACGGAAGCGTATTCACTGTGCGCCAGTACTCCTGGCTGTGCTGTGGTTTCTCCCGACGTGCACATCGA
TCTCGTATGTGTGGCATCTGATATTAAACGGGAGGTTTTAAGAAGCGTCTGCCGTGATCATGGAGCTTCGGAAGCGGGAATGGTTCTTCC
GGGTTTGCTGTTTTGTCTGTTTCCCCCTTGTGTGGTTTCCGCCTGCGACAGTTCCAGAATTTGCTCTCCCACTCAGTGTGCTCTGCAGCT
GTGAGGAAACAGCCTTCGTTAGAGGCGGGAGCAGAGACGAGCCGCTGCTCTGTGTCGTGTTTGCTGTGGCCGCAGGGAGAGGAGCAGGAC
ACGCACCTTTCCAGGGGCCTCTGTGTCCCGCACTGTGTGTGAGTGGACCGCAGCGCGCAGCCACATGCCCTGGCTGCCATGGGCCAGACC
GCCTCCACCTCCCCCGCCCGCCTGGCCTGTCCTGAGTGCATTTCCCTGCACTGTGTCGTCACTGCACAGCCAGTCACCGCGGTCTCAGTC
ATCGGCGCGGATGGCTATGCTGGGGTCCCAGGGTGGCCGCAGCAGTCAGGGTCACTGTGGGAGCCCTGGGGTGGAGTGACAAACCGCATT
GTCCTGTGCCCGCCATGGCAGAAGCGCAGCCTTTGTATGGAGGCCCAACCGCGCTCCCGTCTGGAGAAGCGGCTTCCGGGGTGTGGCTGC
CGGGTCGGCTCTGGTCCACAGCACGGTGCCGGGGCTGCAGGTTGTTGAGGGCTGTGACTCCGTGGGGCTCAGCCAGGCTCCAGCAGGGTC
AGACGTGCTGTTAAGAGCAAAGCCACAGACGATGACTTGTCCATTCTCAGTGGATGCTCCAGGCTGTGCCTACACAGCAGTGCTGGTGAC
ATGTCCAGGGTTCCAGGGCCCGGTGGCCTGGGAGCTGCTTTCTCCCCACTGGCTGGGCTGCATCTGGCCCTGGCTGGAGGCCTTGCTTTG
AGGGGCTGTGACCCTCTTCCCCCAGGCCCTCCCCAGCCGACGACAGCCACCGGAGAGGAGATCGGAACACGATTGTCTCAGATGCAGGGC
GCTGTGCGGGACGAAGCCGCAAGGACTCTCGTATCGGGCCCTTGGGACTCGGGAGGTGCCAGAGGCGGCGGCTGCTCTGGACCTCGGTGT
TCACTGACCTTTGTTTCACTTGCCTCTGCTCGACTCCGAGAGCAGGAAACCCGGCCGTGGCCTGGCAGCTCCGCCTCCCATGCCCGCACG
CTGGGGTCTGTCTTGTCTGGAGCAGTGGGGCACACCCCGGAGGAGGCGGGGGTCAGGGCTGTCGGCCTTGGCCCCCTGCTGGTCGCTGTT
TCGGGGACTCGGGGCGGCCAGTACCACCGCCTGAGGCGGGGCTCAGCAGCGTTGCATGTACGGGCCTCGTACTGCCTCATGGAAAATCCT
CCGGAGCCGCCCTCCATTGTGGGTTCCTGAGAGTAGGACACATTGCCATGGTTTTGTGGGAATCACGCGCCCCTGATGGAACTTTTCTGC

>81455_81455_3_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000417295_MUM1_chr19_1357008_ENST00000344663_length(amino acids)=706AA_BP=15
MSVAGLKKQFYKASQVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVA
LDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSE
NPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPG
LPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPD
SQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKG
FTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKGSPEEP
VVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQG

--------------------------------------------------------------
>81455_81455_4_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000417295_MUM1_chr19_1357008_ENST00000591806_length(transcript)=4132nt_BP=202nt
GCGAGCGGCTGAGGCGGCGCCGGGGCGGGCGCGGAGCTGGCAAGCGGGTGGCGGAGGCGGCGCCGACGGGGACTGCTGAGGCGCGCAGAG
GGTCGGCGGCGCCCGGGAGCCTGTCGCTGGCGCGGTCCGGGCGGGAGGCTCGGCGGCGGGCGGCAGCATGTCGGTGGCGGGGCTGAAGAA
GCAGTTCTACAAGGCGAGCCAGGTTTTGGCCCGAACCGCGACTTCAACAAAAAATAAGAGAAGAAAGGAATATTTTCTAGCTGTGCAAAT
CCTCTCTCTAGAGGAAAAAATTAAGGTGAAAAGCACTGAAGTTGAGATCCTAGAGAAGTCTCAAATTGAAGCCATTGCTTCCTCGTTAGC
CTCACAGAATGAGGTTCCTGCGGCACCCCTGGAAGAACTGGCCTACAGACGGTCGCTTCGCGTGGCTCTGGACGTTCTGAGCGAGGGCTC
GATTTGGAGTCAAGAAAGCTCTGCAGGGACAGGTAGAGCTGACCGGTCTCTGCGAGGGAAGCCCATGGAGCATGTCTCCTCGCCCTGTGA
TTCGAACTCCTCATCTCTTCCCCGCGGAGACGTGTTGGGCAGTTCCAGACCTCACAGGAGGAGGCCATGTGTGCAACAAAGCCTGTCAAG
TTCGTTCACTTGTGAAAAGGACCCCGAGTGCAAAGTGGACCACAAGAAGGGGCTCAGGAAAAGTGAAAACCCAAGAGGCCCGTTGGTCCT
CCCAGCTGGAGGTGGTGCCCAAGATGAGAGTGGGTCCAGAATCCACCACAAAAATTGGACTCTTGCAAGTAAGAGGGGAGGAAACTCAGC
GCAGAAGGCTAGCTTGTGCCTGAATGGATCTTCCCTTTCAGAGGACGACACGGAGAGAGACATGGGGAGCAAAGGAGGCAGCTGGGCAGC
CCCGTCCTTGCCCTCCGGGGTCAGGGAGGACGATCCCTGTGCCAACGCTGAGGGACACGACCCCGGTCTGCCGTTGGGCAGCCTCACTGC
GCCCCCAGCCCCTGAGCCCTCGGCCTGCTCAGAGCCTGGAGAATGCCCTGCGAAAAAGAGGCCGCGCCTGGATGGCAGCCAAAGGCCGCC
TGCCGTGCAGCTGGAGCCCATGGCAGCAGGGGCCGCACCATCCCCCGGGCCGGGGCCAGGGCCCAGAGAGTCTGTGACCCCGCGCAGCAC
CGCCAGGCTGGGCCCGCCTCCCTCCCACGCCTCTGCGGATGCAACCAGATGTCTTCCTTGCCCGGATTCCCAGAAGCTGGAGAAAGAGTG
CCAGTCTTCCGAAGAGTCCATGGGGTCTAATTCCATGCGTTCTATCCTGGAGGAAGACGAGGAAGACGAGGAGCCACCAAGAGTCCTTTT
ATACCACGAACCACGTTCGTTTGAAGTAGGAATGCTAGTCTGGCATAAACATAAAAAATACCCCTTCTGGCCAGCAGTGGTCAAAAGCGT
CAGGCAGAGAGATAAGAAAGCAAGTGTGCTATACATCGAAGGACACATGAACCCGAAAATGAAAGGTTTCACAGTGTCTCTTAAAAGTTT
AAAGCACTTTGATTGTAAAGAGAAACAGACGCTTCTGAATCAAGCCAGGGAGGACTTCAACCAGGACATCGGCTGGTGTGTCTCCCTCAT
CACCGACTACAGGGTCCGGTTAGGCTGCGGGTCTTTTGCTGGCTCTTTCCTGGAATATTACGCGGCTGATATAAGCTATCCTGTCCGAAA
ATCCATCCAGCAGGACGTCTTGGGGACCAAGCTTCCTCAACTGAGCAAGGGGAGCCCCGAGGAGCCCGTGGTGGGGTGCCCCCTGGGGCA
GAGGCAGCCCTGCCGGAAAATGCTCCCCGACCGCTCGCGGGCCGCCCGGGACCGGGCCAACCAGAAGCTGGTGGAGTACATTGTGAAGGC
CAAGGGCGCGGAGAGCCACCTGCGGGCCATCCTAAAGAGCAGGAAGCCATCTCGCTGGCTGCAGACCTTCCTGAGCTCCAGCCAGTACGT
GACCTGTGTGGAGACCTACCTGGAGGATGAGGGGCAGCTGGACCTGGTGGTGAAGTACCTGCAGGGCGTCTACCAGGAGGTGGGGGCCAA
GGTGCTCCAGCGCACCAACGGCGACCGGATCCGGTTCATTCTGGACGTGCTTCTGCCCGAGGCCATCATCTGTGCGATCTCTGCGGTGGA
CGAGGTGGACTACAAGACGGCTGAGGAGAAGTACATCAAGGGGCCTTCGCTGAGCTACCGGGAAAAAGAAATATTTGACAACCAGCTCCT
TGAAGAGCGGAACCGGCGCCGTCGGTGAGGGAGCAGCCGGCTGTGCTGTCAGCGGGGCCTGGCGGTGGAAGCGCCTCCAGTGTGCATGAG
CGTGTCTGAAGATGGGGGGCTCAGGGGGCACGTTTGCGTTTGGACCTGTCTGTGCGTTCTCCTGCGTGGCAGTCCTGATTTCCATGCTTC
TGGAGAATCCATTTCGTTAACACTGAAAGCCAGTTCTCTTTTCCTGGCAGTTTTTTTCATTTTATTTTTGGCATTTTTTACAAGATACCG
TTCGGGAAAGGCTTTTGAAAGGACGGAAGCGTATTCACTGTGCGCCAGTACTCCTGGCTGTGCTGTGGTTTCTCCCGACGTGCACATCGA
TCTCGTATGTGTGGCATCTGATATTAAACGGGAGGTTTTAAGAAGCGTCTGCCGTGATCATGGAGCTTCGGAAGCGGGAATGGTTCTTCC
GGGTTTGCTGTTTTGTCTGTTTCCCCCTTGTGTGGTTTCCGCCTGCGACAGTTCCAGAATTTGCTCTCCCACTCAGTGTGCTCTGCAGCT
GTGAGGAAACAGCCTTCGTTAGAGGCGGGAGCAGAGACGAGCCGCTGCTCTGTGTCGTGTTTGCTGTGGCCGCAGGGAGAGGAGCAGGAC
ACGCACCTTTCCAGGGGCCTCTGTGTCCCGCACTGTGTGTGAGTGGACCGCAGCGCGCAGCCACATGCCCTGGCTGCCATGGGCCAGACC
GCCTCCACCTCCCCCGCCCGCCTGGCCTGTCCTGAGTGCATTTCCCTGCACTGTGTCGTCACTGCACAGCCAGTCACCGCGGTCTCAGTC
ATCGGCGCGGATGGCTATGCTGGGGTCCCAGGGTGGCCGCAGCAGTCAGGGTCACTGTGGGAGCCCTGGGGTGGAGTGACAAACCGCATT
GTCCTGTGCCCGCCATGGCAGAAGCGCAGCCTTTGTATGGAGGCCCAACCGCGCTCCCGTCTGGAGAAGCGGCTTCCGGGGTGTGGCTGC
CGGGTCGGCTCTGGTCCACAGCACGGTGCCGGGGCTGCAGGTTGTTGAGGGCTGTGACTCCGTGGGGCTCAGCCAGGCTCCAGCAGGGTC
AGACGTGCTGTTAAGAGCAAAGCCACAGACGATGACTTGTCCATTCTCAGTGGATGCTCCAGGCTGTGCCTACACAGCAGTGCTGGTGAC
ATGTCCAGGGTTCCAGGGCCCGGTGGCCTGGGAGCTGCTTTCTCCCCACTGGCTGGGCTGCATCTGGCCCTGGCTGGAGGCCTTGCTTTG
AGGGGCTGTGACCCTCTTCCCCCAGGCCCTCCCCAGCCGACGACAGCCACCGGAGAGGAGATCGGAACACGATTGTCTCAGATGCAGGGC
GCTGTGCGGGACGAAGCCGCAAGGACTCTCGTATCGGGCCCTTGGGACTCGGGAGGTGCCAGAGGCGGCGGCTGCTCTGGACCTCGGTGT
TCACTGACCTTTGTTTCACTTGCCTCTGCTCGACTCCGAGAGCAGGAAACCCGGCCGTGGCCTGGCAGCTCCGCCTCCCATGCCCGCACG
CTGGGGTCTGTCTTGTCTGGAGCAGTGGGGCACACCCCGGAGGAGGCGGGGGTCAGGGCTGTCGGCCTTGGCCCCCTGCTGGTCGCTGTT
TCGGGGACTCGGGGCGGCCAGTACCACCGCCTGAGGCGGGGCTCAGCAGCGTTGCATGTACGGGCCTCGTACTGCCTCATGGAAAATCCT
CCGGAGCCGCCCTCCATTGTGGGTTCCTGAGAGTAGGACACATTGCCATGGTTTTGTGGGAATCACGCGCCCCTGATGGAACTTTTCTGC

>81455_81455_4_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000417295_MUM1_chr19_1357008_ENST00000591806_length(amino acids)=706AA_BP=15
MSVAGLKKQFYKASQVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVA
LDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSE
NPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPG
LPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPD
SQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKG
FTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKGSPEEP
VVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQG

--------------------------------------------------------------
>81455_81455_5_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000598564_MUM1_chr19_1357008_ENST00000344663_length(transcript)=4026nt_BP=95nt
AGCCTGTCGCTGGCGCGGTCCGGGCGGGAGGCTCGGCGGCGGGCGGCAGCATGTCGGTGGCGGGGCTGAAGAAGCAGTTCTACAAGGCGA
GCCAGGTTTTGGCCCGAACCGCGACTTCAACAAAAAATAAGAGAAGAAAGGAATATTTTCTAGCTGTGCAAATCCTCTCTCTAGAGGAAA
AAATTAAGGTGAAAAGCACTGAAGTTGAGATCCTAGAGAAGTCTCAAATTGAAGCCATTGCTTCCTCGTTAGCCTCACAGAATGAGGTTC
CTGCGGCACCCCTGGAAGAACTGGCCTACAGACGGTCGCTTCGCGTGGCTCTGGACGTTCTGAGCGAGGGCTCGATTTGGAGTCAAGAAA
GCTCTGCAGGGACAGGTAGAGCTGACCGGTCTCTGCGAGGGAAGCCCATGGAGCATGTCTCCTCGCCCTGTGATTCGAACTCCTCATCTC
TTCCCCGCGGAGACGTGTTGGGCAGTTCCAGACCTCACAGGAGGAGGCCATGTGTGCAACAAAGCCTGTCAAGTTCGTTCACTTGTGAAA
AGGACCCCGAGTGCAAAGTGGACCACAAGAAGGGGCTCAGGAAAAGTGAAAACCCAAGAGGCCCGTTGGTCCTCCCAGCTGGAGGTGGTG
CCCAAGATGAGAGTGGGTCCAGAATCCACCACAAAAATTGGACTCTTGCAAGTAAGAGGGGAGGAAACTCAGCGCAGAAGGCTAGCTTGT
GCCTGAATGGATCTTCCCTTTCAGAGGACGACACGGAGAGAGACATGGGGAGCAAAGGAGGCAGCTGGGCAGCCCCGTCCTTGCCCTCCG
GGGTCAGGGAGGACGATCCCTGTGCCAACGCTGAGGGACACGACCCCGGTCTGCCGTTGGGCAGCCTCACTGCGCCCCCAGCCCCTGAGC
CCTCGGCCTGCTCAGAGCCTGGAGAATGCCCTGCGAAAAAGAGGCCGCGCCTGGATGGCAGCCAAAGGCCGCCTGCCGTGCAGCTGGAGC
CCATGGCAGCAGGGGCCGCACCATCCCCCGGGCCGGGGCCAGGGCCCAGAGAGTCTGTGACCCCGCGCAGCACCGCCAGGCTGGGCCCGC
CTCCCTCCCACGCCTCTGCGGATGCAACCAGATGTCTTCCTTGCCCGGATTCCCAGAAGCTGGAGAAAGAGTGCCAGTCTTCCGAAGAGT
CCATGGGGTCTAATTCCATGCGTTCTATCCTGGAGGAAGACGAGGAAGACGAGGAGCCACCAAGAGTCCTTTTATACCACGAACCACGTT
CGTTTGAAGTAGGAATGCTAGTCTGGCATAAACATAAAAAATACCCCTTCTGGCCAGCAGTGGTCAAAAGCGTCAGGCAGAGAGATAAGA
AAGCAAGTGTGCTATACATCGAAGGACACATGAACCCGAAAATGAAAGGTTTCACAGTGTCTCTTAAAAGTTTAAAGCACTTTGATTGTA
AAGAGAAACAGACGCTTCTGAATCAAGCCAGGGAGGACTTCAACCAGGACATCGGCTGGTGTGTCTCCCTCATCACCGACTACAGGGTCC
GGTTAGGCTGCGGGTCTTTTGCTGGCTCTTTCCTGGAATATTACGCGGCTGATATAAGCTATCCTGTCCGAAAATCCATCCAGCAGGACG
TCTTGGGGACCAAGCTTCCTCAACTGAGCAAGGGGAGCCCCGAGGAGCCCGTGGTGGGGTGCCCCCTGGGGCAGAGGCAGCCCTGCCGGA
AAATGCTCCCCGACCGCTCGCGGGCCGCCCGGGACCGGGCCAACCAGAAGCTGGTGGAGTACATTGTGAAGGCCAAGGGCGCGGAGAGCC
ACCTGCGGGCCATCCTAAAGAGCAGGAAGCCATCTCGCTGGCTGCAGACCTTCCTGAGCTCCAGCCAGTACGTGACCTGTGTGGAGACCT
ACCTGGAGGATGAGGGGCAGCTGGACCTGGTGGTGAAGTACCTGCAGGGCGTCTACCAGGAGGTGGGGGCCAAGGTGCTCCAGCGCACCA
ACGGCGACCGGATCCGGTTCATTCTGGACGTGCTTCTGCCCGAGGCCATCATCTGTGCGATCTCTGCGGTGGACGAGGTGGACTACAAGA
CGGCTGAGGAGAAGTACATCAAGGGGCCTTCGCTGAGCTACCGGGAAAAAGAAATATTTGACAACCAGCTCCTTGAAGAGCGGAACCGGC
GCCGTCGGTGAGGGAGCAGCCGGCTGTGCTGTCAGCGGGGCCTGGCGGTGGAAGCGCCTCCAGTGTGCATGAGCGTGTCTGAAGATGGGG
GGCTCAGGGGGCACGTTTGCGTTTGGACCTGTCTGTGCGTTCTCCTGCGTGGCAGTCCTGATTTCCATGCTTCTGGAGAATCCATTTCGT
TAACACTGAAAGCCAGTTCTCTTTTCCTGGCAGTTTTTTTCATTTTATTTTTGGCATTTTTTACAAGATACCGTTCGGGAAAGGCTTTTG
AAAGGACGGAAGCGTATTCACTGTGCGCCAGTACTCCTGGCTGTGCTGTGGTTTCTCCCGACGTGCACATCGATCTCGTATGTGTGGCAT
CTGATATTAAACGGGAGGTTTTAAGAAGCGTCTGCCGTGATCATGGAGCTTCGGAAGCGGGAATGGTTCTTCCGGGTTTGCTGTTTTGTC
TGTTTCCCCCTTGTGTGGTTTCCGCCTGCGACAGTTCCAGAATTTGCTCTCCCACTCAGTGTGCTCTGCAGCTGTGAGGAAACAGCCTTC
GTTAGAGGCGGGAGCAGAGACGAGCCGCTGCTCTGTGTCGTGTTTGCTGTGGCCGCAGGGAGAGGAGCAGGACACGCACCTTTCCAGGGG
CCTCTGTGTCCCGCACTGTGTGTGAGTGGACCGCAGCGCGCAGCCACATGCCCTGGCTGCCATGGGCCAGACCGCCTCCACCTCCCCCGC
CCGCCTGGCCTGTCCTGAGTGCATTTCCCTGCACTGTGTCGTCACTGCACAGCCAGTCACCGCGGTCTCAGTCATCGGCGCGGATGGCTA
TGCTGGGGTCCCAGGGTGGCCGCAGCAGTCAGGGTCACTGTGGGAGCCCTGGGGTGGAGTGACAAACCGCATTGTCCTGTGCCCGCCATG
GCAGAAGCGCAGCCTTTGTATGGAGGCCCAACCGCGCTCCCGTCTGGAGAAGCGGCTTCCGGGGTGTGGCTGCCGGGTCGGCTCTGGTCC
ACAGCACGGTGCCGGGGCTGCAGGTTGTTGAGGGCTGTGACTCCGTGGGGCTCAGCCAGGCTCCAGCAGGGTCAGACGTGCTGTTAAGAG
CAAAGCCACAGACGATGACTTGTCCATTCTCAGTGGATGCTCCAGGCTGTGCCTACACAGCAGTGCTGGTGACATGTCCAGGGTTCCAGG
GCCCGGTGGCCTGGGAGCTGCTTTCTCCCCACTGGCTGGGCTGCATCTGGCCCTGGCTGGAGGCCTTGCTTTGAGGGGCTGTGACCCTCT
TCCCCCAGGCCCTCCCCAGCCGACGACAGCCACCGGAGAGGAGATCGGAACACGATTGTCTCAGATGCAGGGCGCTGTGCGGGACGAAGC
CGCAAGGACTCTCGTATCGGGCCCTTGGGACTCGGGAGGTGCCAGAGGCGGCGGCTGCTCTGGACCTCGGTGTTCACTGACCTTTGTTTC
ACTTGCCTCTGCTCGACTCCGAGAGCAGGAAACCCGGCCGTGGCCTGGCAGCTCCGCCTCCCATGCCCGCACGCTGGGGTCTGTCTTGTC
TGGAGCAGTGGGGCACACCCCGGAGGAGGCGGGGGTCAGGGCTGTCGGCCTTGGCCCCCTGCTGGTCGCTGTTTCGGGGACTCGGGGCGG
CCAGTACCACCGCCTGAGGCGGGGCTCAGCAGCGTTGCATGTACGGGCCTCGTACTGCCTCATGGAAAATCCTCCGGAGCCGCCCTCCAT
TGTGGGTTCCTGAGAGTAGGACACATTGCCATGGTTTTGTGGGAATCACGCGCCCCTGATGGAACTTTTCTGCTGTTGTGAAGTACTTTT

>81455_81455_5_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000598564_MUM1_chr19_1357008_ENST00000344663_length(amino acids)=706AA_BP=15
MSVAGLKKQFYKASQVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVA
LDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSE
NPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPG
LPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPD
SQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKG
FTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKGSPEEP
VVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQG

--------------------------------------------------------------
>81455_81455_6_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000598564_MUM1_chr19_1357008_ENST00000591806_length(transcript)=4025nt_BP=95nt
AGCCTGTCGCTGGCGCGGTCCGGGCGGGAGGCTCGGCGGCGGGCGGCAGCATGTCGGTGGCGGGGCTGAAGAAGCAGTTCTACAAGGCGA
GCCAGGTTTTGGCCCGAACCGCGACTTCAACAAAAAATAAGAGAAGAAAGGAATATTTTCTAGCTGTGCAAATCCTCTCTCTAGAGGAAA
AAATTAAGGTGAAAAGCACTGAAGTTGAGATCCTAGAGAAGTCTCAAATTGAAGCCATTGCTTCCTCGTTAGCCTCACAGAATGAGGTTC
CTGCGGCACCCCTGGAAGAACTGGCCTACAGACGGTCGCTTCGCGTGGCTCTGGACGTTCTGAGCGAGGGCTCGATTTGGAGTCAAGAAA
GCTCTGCAGGGACAGGTAGAGCTGACCGGTCTCTGCGAGGGAAGCCCATGGAGCATGTCTCCTCGCCCTGTGATTCGAACTCCTCATCTC
TTCCCCGCGGAGACGTGTTGGGCAGTTCCAGACCTCACAGGAGGAGGCCATGTGTGCAACAAAGCCTGTCAAGTTCGTTCACTTGTGAAA
AGGACCCCGAGTGCAAAGTGGACCACAAGAAGGGGCTCAGGAAAAGTGAAAACCCAAGAGGCCCGTTGGTCCTCCCAGCTGGAGGTGGTG
CCCAAGATGAGAGTGGGTCCAGAATCCACCACAAAAATTGGACTCTTGCAAGTAAGAGGGGAGGAAACTCAGCGCAGAAGGCTAGCTTGT
GCCTGAATGGATCTTCCCTTTCAGAGGACGACACGGAGAGAGACATGGGGAGCAAAGGAGGCAGCTGGGCAGCCCCGTCCTTGCCCTCCG
GGGTCAGGGAGGACGATCCCTGTGCCAACGCTGAGGGACACGACCCCGGTCTGCCGTTGGGCAGCCTCACTGCGCCCCCAGCCCCTGAGC
CCTCGGCCTGCTCAGAGCCTGGAGAATGCCCTGCGAAAAAGAGGCCGCGCCTGGATGGCAGCCAAAGGCCGCCTGCCGTGCAGCTGGAGC
CCATGGCAGCAGGGGCCGCACCATCCCCCGGGCCGGGGCCAGGGCCCAGAGAGTCTGTGACCCCGCGCAGCACCGCCAGGCTGGGCCCGC
CTCCCTCCCACGCCTCTGCGGATGCAACCAGATGTCTTCCTTGCCCGGATTCCCAGAAGCTGGAGAAAGAGTGCCAGTCTTCCGAAGAGT
CCATGGGGTCTAATTCCATGCGTTCTATCCTGGAGGAAGACGAGGAAGACGAGGAGCCACCAAGAGTCCTTTTATACCACGAACCACGTT
CGTTTGAAGTAGGAATGCTAGTCTGGCATAAACATAAAAAATACCCCTTCTGGCCAGCAGTGGTCAAAAGCGTCAGGCAGAGAGATAAGA
AAGCAAGTGTGCTATACATCGAAGGACACATGAACCCGAAAATGAAAGGTTTCACAGTGTCTCTTAAAAGTTTAAAGCACTTTGATTGTA
AAGAGAAACAGACGCTTCTGAATCAAGCCAGGGAGGACTTCAACCAGGACATCGGCTGGTGTGTCTCCCTCATCACCGACTACAGGGTCC
GGTTAGGCTGCGGGTCTTTTGCTGGCTCTTTCCTGGAATATTACGCGGCTGATATAAGCTATCCTGTCCGAAAATCCATCCAGCAGGACG
TCTTGGGGACCAAGCTTCCTCAACTGAGCAAGGGGAGCCCCGAGGAGCCCGTGGTGGGGTGCCCCCTGGGGCAGAGGCAGCCCTGCCGGA
AAATGCTCCCCGACCGCTCGCGGGCCGCCCGGGACCGGGCCAACCAGAAGCTGGTGGAGTACATTGTGAAGGCCAAGGGCGCGGAGAGCC
ACCTGCGGGCCATCCTAAAGAGCAGGAAGCCATCTCGCTGGCTGCAGACCTTCCTGAGCTCCAGCCAGTACGTGACCTGTGTGGAGACCT
ACCTGGAGGATGAGGGGCAGCTGGACCTGGTGGTGAAGTACCTGCAGGGCGTCTACCAGGAGGTGGGGGCCAAGGTGCTCCAGCGCACCA
ACGGCGACCGGATCCGGTTCATTCTGGACGTGCTTCTGCCCGAGGCCATCATCTGTGCGATCTCTGCGGTGGACGAGGTGGACTACAAGA
CGGCTGAGGAGAAGTACATCAAGGGGCCTTCGCTGAGCTACCGGGAAAAAGAAATATTTGACAACCAGCTCCTTGAAGAGCGGAACCGGC
GCCGTCGGTGAGGGAGCAGCCGGCTGTGCTGTCAGCGGGGCCTGGCGGTGGAAGCGCCTCCAGTGTGCATGAGCGTGTCTGAAGATGGGG
GGCTCAGGGGGCACGTTTGCGTTTGGACCTGTCTGTGCGTTCTCCTGCGTGGCAGTCCTGATTTCCATGCTTCTGGAGAATCCATTTCGT
TAACACTGAAAGCCAGTTCTCTTTTCCTGGCAGTTTTTTTCATTTTATTTTTGGCATTTTTTACAAGATACCGTTCGGGAAAGGCTTTTG
AAAGGACGGAAGCGTATTCACTGTGCGCCAGTACTCCTGGCTGTGCTGTGGTTTCTCCCGACGTGCACATCGATCTCGTATGTGTGGCAT
CTGATATTAAACGGGAGGTTTTAAGAAGCGTCTGCCGTGATCATGGAGCTTCGGAAGCGGGAATGGTTCTTCCGGGTTTGCTGTTTTGTC
TGTTTCCCCCTTGTGTGGTTTCCGCCTGCGACAGTTCCAGAATTTGCTCTCCCACTCAGTGTGCTCTGCAGCTGTGAGGAAACAGCCTTC
GTTAGAGGCGGGAGCAGAGACGAGCCGCTGCTCTGTGTCGTGTTTGCTGTGGCCGCAGGGAGAGGAGCAGGACACGCACCTTTCCAGGGG
CCTCTGTGTCCCGCACTGTGTGTGAGTGGACCGCAGCGCGCAGCCACATGCCCTGGCTGCCATGGGCCAGACCGCCTCCACCTCCCCCGC
CCGCCTGGCCTGTCCTGAGTGCATTTCCCTGCACTGTGTCGTCACTGCACAGCCAGTCACCGCGGTCTCAGTCATCGGCGCGGATGGCTA
TGCTGGGGTCCCAGGGTGGCCGCAGCAGTCAGGGTCACTGTGGGAGCCCTGGGGTGGAGTGACAAACCGCATTGTCCTGTGCCCGCCATG
GCAGAAGCGCAGCCTTTGTATGGAGGCCCAACCGCGCTCCCGTCTGGAGAAGCGGCTTCCGGGGTGTGGCTGCCGGGTCGGCTCTGGTCC
ACAGCACGGTGCCGGGGCTGCAGGTTGTTGAGGGCTGTGACTCCGTGGGGCTCAGCCAGGCTCCAGCAGGGTCAGACGTGCTGTTAAGAG
CAAAGCCACAGACGATGACTTGTCCATTCTCAGTGGATGCTCCAGGCTGTGCCTACACAGCAGTGCTGGTGACATGTCCAGGGTTCCAGG
GCCCGGTGGCCTGGGAGCTGCTTTCTCCCCACTGGCTGGGCTGCATCTGGCCCTGGCTGGAGGCCTTGCTTTGAGGGGCTGTGACCCTCT
TCCCCCAGGCCCTCCCCAGCCGACGACAGCCACCGGAGAGGAGATCGGAACACGATTGTCTCAGATGCAGGGCGCTGTGCGGGACGAAGC
CGCAAGGACTCTCGTATCGGGCCCTTGGGACTCGGGAGGTGCCAGAGGCGGCGGCTGCTCTGGACCTCGGTGTTCACTGACCTTTGTTTC
ACTTGCCTCTGCTCGACTCCGAGAGCAGGAAACCCGGCCGTGGCCTGGCAGCTCCGCCTCCCATGCCCGCACGCTGGGGTCTGTCTTGTC
TGGAGCAGTGGGGCACACCCCGGAGGAGGCGGGGGTCAGGGCTGTCGGCCTTGGCCCCCTGCTGGTCGCTGTTTCGGGGACTCGGGGCGG
CCAGTACCACCGCCTGAGGCGGGGCTCAGCAGCGTTGCATGTACGGGCCTCGTACTGCCTCATGGAAAATCCTCCGGAGCCGCCCTCCAT
TGTGGGTTCCTGAGAGTAGGACACATTGCCATGGTTTTGTGGGAATCACGCGCCCCTGATGGAACTTTTCTGCTGTTGTGAAGTACTTTT

>81455_81455_6_SH3GL1-MUM1_SH3GL1_chr19_4400321_ENST00000598564_MUM1_chr19_1357008_ENST00000591806_length(amino acids)=706AA_BP=15
MSVAGLKKQFYKASQVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVA
LDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSE
NPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPG
LPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPD
SQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKG
FTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKGSPEEP
VVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SH3GL1-MUM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000269886-110218_25415.0369.0ARC
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000417295-19218_25415.0321.0ARC
HgeneSH3GL1chr19:4400321chr19:1357008ENST00000598564-110218_25415.0305.0ARC


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SH3GL1-MUM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SH3GL1-MUM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource