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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SH3PXD2A-RB1 (FusionGDB2 ID:81514) |
Fusion Gene Summary for SH3PXD2A-RB1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SH3PXD2A-RB1 | Fusion gene ID: 81514 | Hgene | Tgene | Gene symbol | SH3PXD2A | RB1 | Gene ID | 9644 | 5925 |
| Gene name | SH3 and PX domains 2A | RB transcriptional corepressor 1 | |
| Synonyms | FISH|SH3MD1|TKS5 | OSRC|PPP1R130|RB|p105-Rb|p110-RB1|pRb|pp110 | |
| Cytomap | 10q24.33 | 13q14.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | SH3 and PX domain-containing protein 2ASH3 multiple domains 1adapter protein TKS5adaptor protein TKS5five SH3 domain-containing proteintyrosine kinase substrate with five SH3 domains | retinoblastoma-associated proteinGOS563 exon 17 substitution mutation causes premature stopexon 17 tumor GOS561 substitution mutation causes premature stopprepro-retinoblastoma-associated proteinprotein phosphatase 1, regulatory subunit 130retinoblas | |
| Modification date | 20200313 | 20200329 | |
| UniProtAcc | . | RB1CC1 | |
| Ensembl transtripts involved in fusion gene | ENST00000355946, ENST00000369774, ENST00000427662, ENST00000538130, ENST00000540321, ENST00000315994, | ENST00000484879, ENST00000267163, | |
| Fusion gene scores | * DoF score | 12 X 20 X 12=2880 | 13 X 16 X 11=2288 |
| # samples | 29 | 27 | |
| ** MAII score | log2(29/2880*10)=-3.31194400631474 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(27/2288*10)=-3.08305573972756 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SH3PXD2A [Title/Abstract] AND RB1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SH3PXD2A(105371338)-RB1(49039134), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SH3PXD2A | GO:0006801 | superoxide metabolic process | 19755710 |
| Tgene | RB1 | GO:0043550 | regulation of lipid kinase activity | 16286473 |
| Tgene | RB1 | GO:0045892 | negative regulation of transcription, DNA-templated | 10783144|12065415|19223331 |
| Tgene | RB1 | GO:2000679 | positive regulation of transcription regulatory region DNA binding | 25100735 |
| Fusion gene breakpoints across SH3PXD2A (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across RB1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | OV | TCGA-24-1469-01A | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| ChimerDB4 | OV | TCGA-24-1469 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
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Fusion Gene ORF analysis for SH3PXD2A-RB1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000355946 | ENST00000484879 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| 5CDS-intron | ENST00000355946 | ENST00000484879 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| 5CDS-intron | ENST00000369774 | ENST00000484879 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| 5CDS-intron | ENST00000369774 | ENST00000484879 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| 5CDS-intron | ENST00000427662 | ENST00000484879 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| 5CDS-intron | ENST00000427662 | ENST00000484879 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| 5CDS-intron | ENST00000538130 | ENST00000484879 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| 5CDS-intron | ENST00000538130 | ENST00000484879 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| 5CDS-intron | ENST00000540321 | ENST00000484879 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| 5CDS-intron | ENST00000540321 | ENST00000484879 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| 5UTR-3CDS | ENST00000315994 | ENST00000267163 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| 5UTR-3CDS | ENST00000315994 | ENST00000267163 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| 5UTR-intron | ENST00000315994 | ENST00000484879 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| 5UTR-intron | ENST00000315994 | ENST00000484879 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| In-frame | ENST00000355946 | ENST00000267163 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| In-frame | ENST00000355946 | ENST00000267163 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| In-frame | ENST00000369774 | ENST00000267163 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| In-frame | ENST00000369774 | ENST00000267163 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| In-frame | ENST00000427662 | ENST00000267163 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| In-frame | ENST00000427662 | ENST00000267163 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| In-frame | ENST00000538130 | ENST00000267163 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| In-frame | ENST00000538130 | ENST00000267163 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| In-frame | ENST00000540321 | ENST00000267163 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + |
| In-frame | ENST00000540321 | ENST00000267163 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000427662 | SH3PXD2A | chr10 | 105371338 | - | ENST00000267163 | RB1 | chr13 | 49039134 | + | 3472 | 981 | 87 | 1556 | 489 |
| ENST00000369774 | SH3PXD2A | chr10 | 105371338 | - | ENST00000267163 | RB1 | chr13 | 49039134 | + | 4076 | 1585 | 202 | 2160 | 652 |
| ENST00000355946 | SH3PXD2A | chr10 | 105371338 | - | ENST00000267163 | RB1 | chr13 | 49039134 | + | 3855 | 1364 | 65 | 1939 | 624 |
| ENST00000540321 | SH3PXD2A | chr10 | 105371338 | - | ENST00000267163 | RB1 | chr13 | 49039134 | + | 3411 | 920 | 11 | 1495 | 494 |
| ENST00000538130 | SH3PXD2A | chr10 | 105371338 | - | ENST00000267163 | RB1 | chr13 | 49039134 | + | 3395 | 904 | 52 | 1479 | 475 |
| ENST00000427662 | SH3PXD2A | chr10 | 105371337 | - | ENST00000267163 | RB1 | chr13 | 49039133 | + | 3472 | 981 | 87 | 1556 | 489 |
| ENST00000369774 | SH3PXD2A | chr10 | 105371337 | - | ENST00000267163 | RB1 | chr13 | 49039133 | + | 4076 | 1585 | 202 | 2160 | 652 |
| ENST00000355946 | SH3PXD2A | chr10 | 105371337 | - | ENST00000267163 | RB1 | chr13 | 49039133 | + | 3855 | 1364 | 65 | 1939 | 624 |
| ENST00000540321 | SH3PXD2A | chr10 | 105371337 | - | ENST00000267163 | RB1 | chr13 | 49039133 | + | 3411 | 920 | 11 | 1495 | 494 |
| ENST00000538130 | SH3PXD2A | chr10 | 105371337 | - | ENST00000267163 | RB1 | chr13 | 49039133 | + | 3395 | 904 | 52 | 1479 | 475 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000427662 | ENST00000267163 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + | 0.000275531 | 0.99972445 |
| ENST00000369774 | ENST00000267163 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + | 0.000289757 | 0.99971026 |
| ENST00000355946 | ENST00000267163 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + | 0.000301897 | 0.99969816 |
| ENST00000540321 | ENST00000267163 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + | 0.000196942 | 0.9998031 |
| ENST00000538130 | ENST00000267163 | SH3PXD2A | chr10 | 105371338 | - | RB1 | chr13 | 49039134 | + | 0.000479589 | 0.9995204 |
| ENST00000427662 | ENST00000267163 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + | 0.000275531 | 0.99972445 |
| ENST00000369774 | ENST00000267163 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + | 0.000289757 | 0.99971026 |
| ENST00000355946 | ENST00000267163 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + | 0.000301897 | 0.99969816 |
| ENST00000540321 | ENST00000267163 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + | 0.000196942 | 0.9998031 |
| ENST00000538130 | ENST00000267163 | SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + | 0.000479589 | 0.9995204 |
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Fusion Genomic Features for SH3PXD2A-RB1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + | 0.001203935 | 0.998796 |
| SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + | 0.001203935 | 0.998796 |
| SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + | 0.001203935 | 0.998796 |
| SH3PXD2A | chr10 | 105371337 | - | RB1 | chr13 | 49039133 | + | 0.001203935 | 0.998796 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SH3PXD2A-RB1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:105371338/chr13:49039134) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | RB1 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | 1594 |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000355946 | - | 12 | 14 | 166_225 | 408 | 1106.0 | Domain | SH3 1 |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000355946 | - | 12 | 14 | 266_325 | 408 | 1106.0 | Domain | SH3 2 |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000355946 | - | 12 | 14 | 4_128 | 408 | 1106.0 | Domain | PX |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000369774 | - | 13 | 15 | 166_225 | 436 | 1134.0 | Domain | SH3 1 |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000369774 | - | 13 | 15 | 266_325 | 436 | 1134.0 | Domain | SH3 2 |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000369774 | - | 13 | 15 | 4_128 | 436 | 1134.0 | Domain | PX |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000355946 | - | 12 | 14 | 166_225 | 408 | 1106.0 | Domain | SH3 1 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000355946 | - | 12 | 14 | 266_325 | 408 | 1106.0 | Domain | SH3 2 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000355946 | - | 12 | 14 | 4_128 | 408 | 1106.0 | Domain | PX |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000369774 | - | 13 | 15 | 166_225 | 436 | 1134.0 | Domain | SH3 1 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000369774 | - | 13 | 15 | 266_325 | 436 | 1134.0 | Domain | SH3 2 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000369774 | - | 13 | 15 | 4_128 | 436 | 1134.0 | Domain | PX |
| Tgene | RB1 | chr10:105371337 | chr13:49039133 | ENST00000267163 | 20 | 27 | 860_876 | 737 | 929.0 | Motif | Bipartite nuclear localization signal | |
| Tgene | RB1 | chr10:105371338 | chr13:49039134 | ENST00000267163 | 20 | 27 | 860_876 | 737 | 929.0 | Motif | Bipartite nuclear localization signal |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000355946 | - | 12 | 14 | 917_946 | 408 | 1106.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000369774 | - | 13 | 15 | 917_946 | 436 | 1134.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000355946 | - | 12 | 14 | 917_946 | 408 | 1106.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000369774 | - | 13 | 15 | 917_946 | 436 | 1134.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000355946 | - | 12 | 14 | 634_724 | 408 | 1106.0 | Compositional bias | Note=Ser-rich |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000369774 | - | 13 | 15 | 634_724 | 436 | 1134.0 | Compositional bias | Note=Ser-rich |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000355946 | - | 12 | 14 | 634_724 | 408 | 1106.0 | Compositional bias | Note=Ser-rich |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000369774 | - | 13 | 15 | 634_724 | 436 | 1134.0 | Compositional bias | Note=Ser-rich |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000355946 | - | 12 | 14 | 1072_1133 | 408 | 1106.0 | Domain | SH3 5 |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000355946 | - | 12 | 14 | 448_507 | 408 | 1106.0 | Domain | SH3 3 |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000355946 | - | 12 | 14 | 840_899 | 408 | 1106.0 | Domain | SH3 4 |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000369774 | - | 13 | 15 | 1072_1133 | 436 | 1134.0 | Domain | SH3 5 |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000369774 | - | 13 | 15 | 448_507 | 436 | 1134.0 | Domain | SH3 3 |
| Hgene | SH3PXD2A | chr10:105371337 | chr13:49039133 | ENST00000369774 | - | 13 | 15 | 840_899 | 436 | 1134.0 | Domain | SH3 4 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000355946 | - | 12 | 14 | 1072_1133 | 408 | 1106.0 | Domain | SH3 5 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000355946 | - | 12 | 14 | 448_507 | 408 | 1106.0 | Domain | SH3 3 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000355946 | - | 12 | 14 | 840_899 | 408 | 1106.0 | Domain | SH3 4 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000369774 | - | 13 | 15 | 1072_1133 | 436 | 1134.0 | Domain | SH3 5 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000369774 | - | 13 | 15 | 448_507 | 436 | 1134.0 | Domain | SH3 3 |
| Hgene | SH3PXD2A | chr10:105371338 | chr13:49039134 | ENST00000369774 | - | 13 | 15 | 840_899 | 436 | 1134.0 | Domain | SH3 4 |
| Tgene | RB1 | chr10:105371337 | chr13:49039133 | ENST00000267163 | 20 | 27 | 10_18 | 737 | 929.0 | Compositional bias | Note=Poly-Ala | |
| Tgene | RB1 | chr10:105371337 | chr13:49039133 | ENST00000267163 | 20 | 27 | 20_29 | 737 | 929.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | RB1 | chr10:105371338 | chr13:49039134 | ENST00000267163 | 20 | 27 | 10_18 | 737 | 929.0 | Compositional bias | Note=Poly-Ala | |
| Tgene | RB1 | chr10:105371338 | chr13:49039134 | ENST00000267163 | 20 | 27 | 20_29 | 737 | 929.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | RB1 | chr10:105371337 | chr13:49039133 | ENST00000267163 | 20 | 27 | 373_579 | 737 | 929.0 | Region | Note=Domain A | |
| Tgene | RB1 | chr10:105371337 | chr13:49039133 | ENST00000267163 | 20 | 27 | 373_771 | 737 | 929.0 | Region | Note=Pocket%3B binds T and E1A | |
| Tgene | RB1 | chr10:105371337 | chr13:49039133 | ENST00000267163 | 20 | 27 | 580_639 | 737 | 929.0 | Region | Note=Spacer | |
| Tgene | RB1 | chr10:105371337 | chr13:49039133 | ENST00000267163 | 20 | 27 | 640_771 | 737 | 929.0 | Region | Note=Domain B | |
| Tgene | RB1 | chr10:105371338 | chr13:49039134 | ENST00000267163 | 20 | 27 | 373_579 | 737 | 929.0 | Region | Note=Domain A | |
| Tgene | RB1 | chr10:105371338 | chr13:49039134 | ENST00000267163 | 20 | 27 | 373_771 | 737 | 929.0 | Region | Note=Pocket%3B binds T and E1A | |
| Tgene | RB1 | chr10:105371338 | chr13:49039134 | ENST00000267163 | 20 | 27 | 580_639 | 737 | 929.0 | Region | Note=Spacer | |
| Tgene | RB1 | chr10:105371338 | chr13:49039134 | ENST00000267163 | 20 | 27 | 640_771 | 737 | 929.0 | Region | Note=Domain B |
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Fusion Gene Sequence for SH3PXD2A-RB1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >81514_81514_1_SH3PXD2A-RB1_SH3PXD2A_chr10_105371337_ENST00000355946_RB1_chr13_49039133_ENST00000267163_length(transcript)=3855nt_BP=1364nt CCGGGAGTCCGGGCAGCGTTCGGCGCGCCGGGCCGGGGTGGCGGGCGGCCCCGGGACCCCGGCAGCTGGAGAAGGAGCCGGAGCCCGGCC GGGATGAGAAGGTGACGCCGCCGGGGGCGCCACTCGCTTTGTGGGGGAAGATGCTCGCCTACTGCGTGCAGGATGCCACCGTGGTGGACG TGGAGAAGCGGAGGAACCCCTCCAAGCACTACGTATACATAATCAATGTGACCTGGTCTGACTCCACCTCCCAGACTATCTACCGGAGGT ACAGCAAGTTCTTTGACCTGCAGATGCAGCTTTTGGATAAGTTTCCCATTGAAGGTGGCCAGAAGGACCCCAAGCAAAGGATCATCCCCT TCCTCCCAGGCAAGATCCTCTTCCGCAGAAGCCACATCCGGGACGTAGCTGTGAAGAGACTGAAGCCCATCGATGAATACTGCCGGGCAC TTGTCCGGCTGCCCCCCCACATCTCACAGTGTGACGAAGTCTTCCGGTTCTTCGAGGCTCGACCCGAGGATGTCAACCCTCCAAAAGAGG ACTATGGCAGTTCCAAGAGGAAATCAGTGTGGCTGTCCAGCTGGGCTGAGTCGCCCAAGAAGGACGTGACAGGTGCCGACGCCACCGCCG AGCCCATGATCCTGGAACAGTACGTGGTGGTGTCCAACTATAAGAAGCAGGAGAACTCGGAGCTGAGCCTCCAGGCCGGGGAGGTGGTGG ATGTCATCGAGAAGAACGAGAGCGGCTGGTGGTTCGTGAGCACTTCTGAGGAGCAGGGCTGGGTCCCTGCCACCTACCTGGAGGCCCAGA ATGGTACTCGGGATGACTCCGACATCAACACCTCTAAGACTGGAGAAGAGGAGAAGTATGTCACCGTGCAGCCTTACACCAGCCAAAGCA AGGACGAGATTGGCTTTGAGAAGGGCGTCACAGTGGAGGTGATCCGGAAGAATCTGGAAGGCTGGTGGTATATCAGATACCTGGGCAAAG AGGGCTGGGCGCCAGCATCCTACCTGAAGAAGGCCAAGGATGACCTGCCAACCCGGAAGAAGAACCTGGCCGGCCCAGTGGAGATCATTG GGAACATCATGGAGATCAGCAACCTGCTGAACAAGAAGGCGTCTGGGGACAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATGAGGCCC CCATTGCCAAGAAGGAGATCAGCCTGCCCATCCTCTGCAATGCCTCCAATGGCAGTGCCGTGGGCGTTCCTGACAGGACTGTCTCCAGGC TGGCCCAGGGCTCTCCAGCTGTGGCCAGGATTGCCCCTCAGCGGGCCCAGATCAGCTCCCCGAACCTACGGACAAGACCTCCACCACGCA GAGAATCCAGCCTGACATTCAAACGTGTTTTGATCAAAGAAGAGGAGTATGATTCTATTATAGTATTCTATAACTCGGTCTTCATGCAGA GACTGAAAACAAATATTTTGCAGTATGCTTCCACCAGGCCCCCTACCTTGTCACCAATACCTCACATTCCTCGAAGCCCTTACAAGTTTC CTAGTTCACCCTTACGGATTCCTGGAGGGAACATCTATATTTCACCCCTGAAGAGTCCATATAAAATTTCAGAAGGTCTGCCAACACCAA CAAAAATGACTCCAAGATCAAGAATCTTAGTATCAATTGGTGAATCATTCGGGACTTCTGAGAAGTTCCAGAAAATAAATCAGATGGTAT GTAACAGCGACCGTGTGCTCAAAAGAAGTGCTGAAGGAAGCAACCCTCCTAAACCACTGAAAAAACTACGCTTTGATATTGAAGGATCAG ATGAAGCAGATGGAAGTAAACATCTCCCAGGAGAGTCCAAATTTCAGCAGAAACTGGCAGAAATGACTTCTACTCGAACACGAATGCAAA AGCAGAAAATGAATGATAGCATGGATACCTCAAACAAGGAAGAGAAATGAGGATCTCAGGACCTTGGTGGACACTGTGTACACCTCTGGA TTCATTGTCTCTCACAGATGTGACTGTATAACTTTCCCAGGTTCTGTTTATGGCCACATTTAATATCTTCAGCTCTTTTTGTGGATATAA AATGTGCAGATGCAATTGTTTGGGTGATTCCTAAGCCACTTGAAATGTTAGTCATTGTTATTTATACAAGATTGAAAATCTTGTGTAAAT CCTGCCATTTAAAAAGTTGTAGCAGATTGTTTCCTCTTCCAAAGTAAAATTGCTGTGCTTTATGGATAGTAAGAATGGCCCTAGAGTGGG AGTCCTGATAACCCAGGCCTGTCTGACTACTTTGCCTTCTTTTGTAGCATATAGGTGATGTTTGCTCTTGTTTTTATTAATTTATATGTA TATTTTTTTAATTTAACATGAACACCCTTAGAAAATGTGTCCTATCTATCTTCCAAATGCAATTTGATTGACTGCCCATTCACCAAAATT ATCCTGAACTCTTCTGCAAAAATGGATATTATTAGAAATTAGAAAAAAATTACTAATTTTACACATTAGATTTTATTTTACTATTGGAAT CTGATATACTGTGTGCTTGTTTTATAAAATTTTGCTTTTAATTAAATAAAAGCTGGAAGCAAAGTATAACCATATGATACTATCATACTA CTGAAACAGATTTCATACCTCAGAATGTAAAAGAACTTACTGATTATTTTCTTCATCCAACTTATGTTTTTAAATGAGGATTATTGATAG TACTCTTGGTTTTTATACCATTCAGATCACTGAATTTATAAAGTACCCATCTAGTACTTGAAAAAGTAAAGTGTTCTGCCAGATCTTAGG TATAGAGGACCCTAACACAGTATATCCCAAGTGCACTTTCTAATGTTTCTGGGTCCTGAAGAATTAAGATACAAATTAATTTTACTCCAT AAACAGACTGTTAATTATAGGAGCCTTAATTTTTTTTTCATAGAGATTTGTCTAATTGCATCTCAAAATTATTCTGCCCTCCTTAATTTG GGAAGGTTTGTGTTTTCTCTGGAATGGTACATGTCTTCCATGTATCTTTTGAACTGGCAATTGTCTATTTATCTTTTATTTTTTTAAGTC AGTATGGTCTAACACTGGCATGTTCAAAGCCACATTATTTCTAGTCCAAAATTACAAGTAATCAAGGGTCATTATGGGTTAGGCATTAAT GTTTCTATCTGATTTTGTGCAAAAGCTTCAAATTAAAACAGCTGCATTAGAAAAAGAGGCGCTTCTCCCCTCCCCTACACCTAAAGGTGT ATTTAAACTATCTTGTGTGATTAACTTATTTAGAGATGCTGTAACTTAAAATAGGGGATATTTAAGGTAGCTTCAGCTAGCTTTTAGGAA AATCACTTTGTCTAACTCAGAATTATTTTTAAAAAGAAATCTGGTCTTGTTAGAAAACAAAATTTTATTTTGTGCTCATTTAAGTTTCAA ACTTACTATTTTGACAGTTATTTTGATAACAATGACACTAGAAAACTTGACTCCATTTCATCATTGTTTCTGCATGAATATCATACAAAT CAGTTAGTTTTTAGGTCAAGGGCTTACTATTTCTGGGTCTTTTGCTACTAAGTTCACATTAGAATTAGTGCCAGAATTTTAGGAACTTCA GAGATCGTGTATTGAGATTTCTTAAATAATGCTTCAGATATTATTGCTTTATTGCTTTTTTGTATTGGTTAAAACTGTACATTTAAAATT GCTATGTTACTATTTTCTACAATTAATAGTTTGTCTATTTTAAAATAAATTAGTTGTTAAGAGTCTTAATGGTCTGATGTTGTGTTCTTT >81514_81514_1_SH3PXD2A-RB1_SH3PXD2A_chr10_105371337_ENST00000355946_RB1_chr13_49039133_ENST00000267163_length(amino acids)=624AA_BP=433 MEKEPEPGRDEKVTPPGAPLALWGKMLAYCVQDATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQK DPKQRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKD VTGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEEEKYVT VQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKKNLAGPVEIIGNIMEISNLLNKKASGDKETPP AEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLAQGSPAVARIAPQRAQISSPNLRTRPPPRRESSLTFKRVLIKEEEYDSIIV FYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEK -------------------------------------------------------------- >81514_81514_2_SH3PXD2A-RB1_SH3PXD2A_chr10_105371337_ENST00000369774_RB1_chr13_49039133_ENST00000267163_length(transcript)=4076nt_BP=1585nt GCGAGCGGGCGAGCGCAGCGCGGCGGCCGCGCGGGAGTGAAGGGGCGCGCGGCAGGCCGGCGGGGAGTCCCCCGGGGCGCACGGAGCCCG CGCGCCCTCCGGGACCCTCCCCCGTCCCTGGGCCGGACCTGTGGGCGCCGGGAGTCCGGGCAGCGTTCGGCGCGCCGGGCCGGGGTGGCG GGCGGCCCCGGGACCCCGGCAGCTGGAGAAGGAGCCGGAGCCCGGCCGGGATGAGAAGGTGACGCCGCCGGGGGCGCCACTCGCTTTGTG GGGGAAGATGCTCGCCTACTGCGTGCAGGATGCCACCGTGGTGGACGTGGAGAAGCGGAGGAACCCCTCCAAGCACTACGTATACATAAT CAATGTGACCTGGTCTGACTCCACCTCCCAGACTATCTACCGGAGGTACAGCAAGTTCTTTGACCTGCAGATGCAGCTTTTGGATAAGTT TCCCATTGAAGGTGGCCAGAAGGACCCCAAGCAAAGGATCATCCCCTTCCTCCCAGGCAAGATCCTCTTCCGCAGAAGCCACATCCGGGA CGTAGCTGTGAAGAGACTGAAGCCCATCGATGAATACTGCCGGGCACTTGTCCGGCTGCCCCCCCACATCTCACAGTGTGACGAAGTCTT CCGGTTCTTCGAGGCTCGACCCGAGGATGTCAACCCTCCAAAAGAGGACTATGGCAGTTCCAAGAGGAAATCAGTGTGGCTGTCCAGCTG GGCTGAGTCGCCCAAGAAGGACGTGACAGGTGCCGACGCCACCGCCGAGCCCATGATCCTGGAACAGTACGTGGTGGTGTCCAACTATAA GAAGCAGGAGAACTCGGAGCTGAGCCTCCAGGCCGGGGAGGTGGTGGATGTCATCGAGAAGAACGAGAGCGGCTGGTGGTTCGTGAGCAC TTCTGAGGAGCAGGGCTGGGTCCCTGCCACCTACCTGGAGGCCCAGAATGGTACTCGGGATGACTCCGACATCAACACCTCTAAGACTGG AGAAGTGTCCAAGAGACGCAAGGCCCATCTGCGGCGCCTGGATCGCCGGTGGACCCTGGGCGGGATGGTCAACAGGCAGCACAGCCGAGA GGAGAAGTATGTCACCGTGCAGCCTTACACCAGCCAAAGCAAGGACGAGATTGGCTTTGAGAAGGGCGTCACAGTGGAGGTGATCCGGAA GAATCTGGAAGGCTGGTGGTATATCAGATACCTGGGCAAAGAGGGCTGGGCGCCAGCATCCTACCTGAAGAAGGCCAAGGATGACCTGCC AACCCGGAAGAAGAACCTGGCCGGCCCAGTGGAGATCATTGGGAACATCATGGAGATCAGCAACCTGCTGAACAAGAAGGCGTCTGGGGA CAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATGAGGCCCCCATTGCCAAGAAGGAGATCAGCCTGCCCATCCTCTGCAATGCCTCCAA TGGCAGTGCCGTGGGCGTTCCTGACAGGACTGTCTCCAGGCTGGCCCAGGGCTCTCCAGCTGTGGCCAGGATTGCCCCTCAGCGGGCCCA GATCAGCTCCCCGAACCTACGGACAAGACCTCCACCACGCAGAGAATCCAGCCTGACATTCAAACGTGTTTTGATCAAAGAAGAGGAGTA TGATTCTATTATAGTATTCTATAACTCGGTCTTCATGCAGAGACTGAAAACAAATATTTTGCAGTATGCTTCCACCAGGCCCCCTACCTT GTCACCAATACCTCACATTCCTCGAAGCCCTTACAAGTTTCCTAGTTCACCCTTACGGATTCCTGGAGGGAACATCTATATTTCACCCCT GAAGAGTCCATATAAAATTTCAGAAGGTCTGCCAACACCAACAAAAATGACTCCAAGATCAAGAATCTTAGTATCAATTGGTGAATCATT CGGGACTTCTGAGAAGTTCCAGAAAATAAATCAGATGGTATGTAACAGCGACCGTGTGCTCAAAAGAAGTGCTGAAGGAAGCAACCCTCC TAAACCACTGAAAAAACTACGCTTTGATATTGAAGGATCAGATGAAGCAGATGGAAGTAAACATCTCCCAGGAGAGTCCAAATTTCAGCA GAAACTGGCAGAAATGACTTCTACTCGAACACGAATGCAAAAGCAGAAAATGAATGATAGCATGGATACCTCAAACAAGGAAGAGAAATG AGGATCTCAGGACCTTGGTGGACACTGTGTACACCTCTGGATTCATTGTCTCTCACAGATGTGACTGTATAACTTTCCCAGGTTCTGTTT ATGGCCACATTTAATATCTTCAGCTCTTTTTGTGGATATAAAATGTGCAGATGCAATTGTTTGGGTGATTCCTAAGCCACTTGAAATGTT AGTCATTGTTATTTATACAAGATTGAAAATCTTGTGTAAATCCTGCCATTTAAAAAGTTGTAGCAGATTGTTTCCTCTTCCAAAGTAAAA TTGCTGTGCTTTATGGATAGTAAGAATGGCCCTAGAGTGGGAGTCCTGATAACCCAGGCCTGTCTGACTACTTTGCCTTCTTTTGTAGCA TATAGGTGATGTTTGCTCTTGTTTTTATTAATTTATATGTATATTTTTTTAATTTAACATGAACACCCTTAGAAAATGTGTCCTATCTAT CTTCCAAATGCAATTTGATTGACTGCCCATTCACCAAAATTATCCTGAACTCTTCTGCAAAAATGGATATTATTAGAAATTAGAAAAAAA TTACTAATTTTACACATTAGATTTTATTTTACTATTGGAATCTGATATACTGTGTGCTTGTTTTATAAAATTTTGCTTTTAATTAAATAA AAGCTGGAAGCAAAGTATAACCATATGATACTATCATACTACTGAAACAGATTTCATACCTCAGAATGTAAAAGAACTTACTGATTATTT TCTTCATCCAACTTATGTTTTTAAATGAGGATTATTGATAGTACTCTTGGTTTTTATACCATTCAGATCACTGAATTTATAAAGTACCCA TCTAGTACTTGAAAAAGTAAAGTGTTCTGCCAGATCTTAGGTATAGAGGACCCTAACACAGTATATCCCAAGTGCACTTTCTAATGTTTC TGGGTCCTGAAGAATTAAGATACAAATTAATTTTACTCCATAAACAGACTGTTAATTATAGGAGCCTTAATTTTTTTTTCATAGAGATTT GTCTAATTGCATCTCAAAATTATTCTGCCCTCCTTAATTTGGGAAGGTTTGTGTTTTCTCTGGAATGGTACATGTCTTCCATGTATCTTT TGAACTGGCAATTGTCTATTTATCTTTTATTTTTTTAAGTCAGTATGGTCTAACACTGGCATGTTCAAAGCCACATTATTTCTAGTCCAA AATTACAAGTAATCAAGGGTCATTATGGGTTAGGCATTAATGTTTCTATCTGATTTTGTGCAAAAGCTTCAAATTAAAACAGCTGCATTA GAAAAAGAGGCGCTTCTCCCCTCCCCTACACCTAAAGGTGTATTTAAACTATCTTGTGTGATTAACTTATTTAGAGATGCTGTAACTTAA AATAGGGGATATTTAAGGTAGCTTCAGCTAGCTTTTAGGAAAATCACTTTGTCTAACTCAGAATTATTTTTAAAAAGAAATCTGGTCTTG TTAGAAAACAAAATTTTATTTTGTGCTCATTTAAGTTTCAAACTTACTATTTTGACAGTTATTTTGATAACAATGACACTAGAAAACTTG ACTCCATTTCATCATTGTTTCTGCATGAATATCATACAAATCAGTTAGTTTTTAGGTCAAGGGCTTACTATTTCTGGGTCTTTTGCTACT AAGTTCACATTAGAATTAGTGCCAGAATTTTAGGAACTTCAGAGATCGTGTATTGAGATTTCTTAAATAATGCTTCAGATATTATTGCTT TATTGCTTTTTTGTATTGGTTAAAACTGTACATTTAAAATTGCTATGTTACTATTTTCTACAATTAATAGTTTGTCTATTTTAAAATAAA TTAGTTGTTAAGAGTCTTAATGGTCTGATGTTGTGTTCTTTGTATTAAGTACACTAATGTTCTCTTTTCTGTCTAGGAGAAGATAGATAG >81514_81514_2_SH3PXD2A-RB1_SH3PXD2A_chr10_105371337_ENST00000369774_RB1_chr13_49039133_ENST00000267163_length(amino acids)=652AA_BP=461 MEKEPEPGRDEKVTPPGAPLALWGKMLAYCVQDATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQK DPKQRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKD VTGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEVSKRRK AHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKKNLA GPVEIIGNIMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLAQGSPAVARIAPQRAQISSPNLR TRPPPRRESSLTFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKIS EGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQKLAEMTS -------------------------------------------------------------- >81514_81514_3_SH3PXD2A-RB1_SH3PXD2A_chr10_105371337_ENST00000427662_RB1_chr13_49039133_ENST00000267163_length(transcript)=3472nt_BP=981nt ACATGAGCAGCGGCACCGGGGACCGACCGCAGCCAGCCCGAGGGCGCCCCTGCAGCTGCAGCCCCGCGCTCGCGCCCGGCCCTAACCATG TCTATCTGTTGTTGCTTCTTTTTCAGGGACTATGGCAGTTCCAAGAGGAAATCAGGTGCCGACGCCACCGCCGAGCCCATGATCCTGGAA CAGTACGTGGTGGTGTCCAACTATAAGAAGCAGGAGAACTCGGAGCTGAGCCTCCAGGCCGGGGAGGTGGTGGATGTCATCGAGAAGAAC GAGAGCGGCTGGTGGTTCGTGAGCACTTCTGAGGAGCAGGGCTGGGTCCCTGCCACCTACCTGGAGGCCCAGAATGGTACTCGGGATGAC TCCGACATCAACACCTCTAAGACTGGAGAAGTGTCCAAGAGACGCAAGGCCCATCTGCGGCGCCTGGATCGCCGGTGGACCCTGGGCGGG ATGGTCAACAGGCAGCACAGCCGAGAGGAGAAGTATGTCACCGTGCAGCCTTACACCAGCCAAAGCAAGGACGAGATTGGCTTTGAGAAG GGCGTCACAGTGGAGGTGATCCGGAAGAATCTGGAAGGCTGGTGGTATATCAGATACCTGGGCAAAGAGGGCTGGGCGCCAGCATCCTAC CTGAAGAAGGCCAAGGATGACCTGCCAACCCGGAAGAAGAACCTGGCCGGCCCAGTGGAGATCATTGGGAACATCATGGAGATCAGCAAC CTGCTGAACAAGAAGGCGTCTGGGGACAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATGAGGCCCCCATTGCCAAGAAGGAGATCAGC CTGCCCATCCTCTGCAATGCCTCCAATGGCAGTGCCGTGGGCGTTCCTGACAGGACTGTCTCCAGGCTGGCCCAGGGCTCTCCAGCTGTG GCCAGGATTGCCCCTCAGCGGGCCCAGATCAGCTCCCCGAACCTACGGACAAGACCTCCACCACGCAGAGAATCCAGCCTGACATTCAAA CGTGTTTTGATCAAAGAAGAGGAGTATGATTCTATTATAGTATTCTATAACTCGGTCTTCATGCAGAGACTGAAAACAAATATTTTGCAG TATGCTTCCACCAGGCCCCCTACCTTGTCACCAATACCTCACATTCCTCGAAGCCCTTACAAGTTTCCTAGTTCACCCTTACGGATTCCT GGAGGGAACATCTATATTTCACCCCTGAAGAGTCCATATAAAATTTCAGAAGGTCTGCCAACACCAACAAAAATGACTCCAAGATCAAGA ATCTTAGTATCAATTGGTGAATCATTCGGGACTTCTGAGAAGTTCCAGAAAATAAATCAGATGGTATGTAACAGCGACCGTGTGCTCAAA AGAAGTGCTGAAGGAAGCAACCCTCCTAAACCACTGAAAAAACTACGCTTTGATATTGAAGGATCAGATGAAGCAGATGGAAGTAAACAT CTCCCAGGAGAGTCCAAATTTCAGCAGAAACTGGCAGAAATGACTTCTACTCGAACACGAATGCAAAAGCAGAAAATGAATGATAGCATG GATACCTCAAACAAGGAAGAGAAATGAGGATCTCAGGACCTTGGTGGACACTGTGTACACCTCTGGATTCATTGTCTCTCACAGATGTGA CTGTATAACTTTCCCAGGTTCTGTTTATGGCCACATTTAATATCTTCAGCTCTTTTTGTGGATATAAAATGTGCAGATGCAATTGTTTGG GTGATTCCTAAGCCACTTGAAATGTTAGTCATTGTTATTTATACAAGATTGAAAATCTTGTGTAAATCCTGCCATTTAAAAAGTTGTAGC AGATTGTTTCCTCTTCCAAAGTAAAATTGCTGTGCTTTATGGATAGTAAGAATGGCCCTAGAGTGGGAGTCCTGATAACCCAGGCCTGTC TGACTACTTTGCCTTCTTTTGTAGCATATAGGTGATGTTTGCTCTTGTTTTTATTAATTTATATGTATATTTTTTTAATTTAACATGAAC ACCCTTAGAAAATGTGTCCTATCTATCTTCCAAATGCAATTTGATTGACTGCCCATTCACCAAAATTATCCTGAACTCTTCTGCAAAAAT GGATATTATTAGAAATTAGAAAAAAATTACTAATTTTACACATTAGATTTTATTTTACTATTGGAATCTGATATACTGTGTGCTTGTTTT ATAAAATTTTGCTTTTAATTAAATAAAAGCTGGAAGCAAAGTATAACCATATGATACTATCATACTACTGAAACAGATTTCATACCTCAG AATGTAAAAGAACTTACTGATTATTTTCTTCATCCAACTTATGTTTTTAAATGAGGATTATTGATAGTACTCTTGGTTTTTATACCATTC AGATCACTGAATTTATAAAGTACCCATCTAGTACTTGAAAAAGTAAAGTGTTCTGCCAGATCTTAGGTATAGAGGACCCTAACACAGTAT ATCCCAAGTGCACTTTCTAATGTTTCTGGGTCCTGAAGAATTAAGATACAAATTAATTTTACTCCATAAACAGACTGTTAATTATAGGAG CCTTAATTTTTTTTTCATAGAGATTTGTCTAATTGCATCTCAAAATTATTCTGCCCTCCTTAATTTGGGAAGGTTTGTGTTTTCTCTGGA ATGGTACATGTCTTCCATGTATCTTTTGAACTGGCAATTGTCTATTTATCTTTTATTTTTTTAAGTCAGTATGGTCTAACACTGGCATGT TCAAAGCCACATTATTTCTAGTCCAAAATTACAAGTAATCAAGGGTCATTATGGGTTAGGCATTAATGTTTCTATCTGATTTTGTGCAAA AGCTTCAAATTAAAACAGCTGCATTAGAAAAAGAGGCGCTTCTCCCCTCCCCTACACCTAAAGGTGTATTTAAACTATCTTGTGTGATTA ACTTATTTAGAGATGCTGTAACTTAAAATAGGGGATATTTAAGGTAGCTTCAGCTAGCTTTTAGGAAAATCACTTTGTCTAACTCAGAAT TATTTTTAAAAAGAAATCTGGTCTTGTTAGAAAACAAAATTTTATTTTGTGCTCATTTAAGTTTCAAACTTACTATTTTGACAGTTATTT TGATAACAATGACACTAGAAAACTTGACTCCATTTCATCATTGTTTCTGCATGAATATCATACAAATCAGTTAGTTTTTAGGTCAAGGGC TTACTATTTCTGGGTCTTTTGCTACTAAGTTCACATTAGAATTAGTGCCAGAATTTTAGGAACTTCAGAGATCGTGTATTGAGATTTCTT AAATAATGCTTCAGATATTATTGCTTTATTGCTTTTTTGTATTGGTTAAAACTGTACATTTAAAATTGCTATGTTACTATTTTCTACAAT TAATAGTTTGTCTATTTTAAAATAAATTAGTTGTTAAGAGTCTTAATGGTCTGATGTTGTGTTCTTTGTATTAAGTACACTAATGTTCTC >81514_81514_3_SH3PXD2A-RB1_SH3PXD2A_chr10_105371337_ENST00000427662_RB1_chr13_49039133_ENST00000267163_length(amino acids)=489AA_BP=298 MSICCCFFFRDYGSSKRKSGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRD DSDINTSKTGEVSKRRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPAS YLKKAKDDLPTRKKNLAGPVEIIGNIMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLAQGSPA VARIAPQRAQISSPNLRTRPPPRRESSLTFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRI PGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSK -------------------------------------------------------------- >81514_81514_4_SH3PXD2A-RB1_SH3PXD2A_chr10_105371337_ENST00000538130_RB1_chr13_49039133_ENST00000267163_length(transcript)=3395nt_BP=904nt GAGAAGCTCTCTCCCGCTCTCTCCTCTCCCTCTCCCGCCCGAGGGAGCAGGGCTGCCTTTTCTCTCGGGTGCCGACGCCACCGCCGAGCC CATGATCCTGGAACAGTACGTGGTGGTGTCCAACTATAAGAAGCAGGAGAACTCGGAGCTGAGCCTCCAGGCCGGGGAGGTGGTGGATGT CATCGAGAAGAACGAGAGCGGCTGGTGGTTCGTGAGCACTTCTGAGGAGCAGGGCTGGGTCCCTGCCACCTACCTGGAGGCCCAGAATGG TACTCGGGATGACTCCGACATCAACACCTCTAAGACTGGAGAAGTGTCCAAGAGACGCAAGGCCCATCTGCGGCGCCTGGATCGCCGGTG GACCCTGGGCGGGATGGTCAACAGGCAGCACAGCCGAGAGGAGAAGTATGTCACCGTGCAGCCTTACACCAGCCAAAGCAAGGACGAGAT TGGCTTTGAGAAGGGCGTCACAGTGGAGGTGATCCGGAAGAATCTGGAAGGCTGGTGGTATATCAGATACCTGGGCAAAGAGGGCTGGGC GCCAGCATCCTACCTGAAGAAGGCCAAGGATGACCTGCCAACCCGGAAGAAGAACCTGGCCGGCCCAGTGGAGATCATTGGGAACATCAT GGAGATCAGCAACCTGCTGAACAAGAAGGCGTCTGGGGACAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATGAGGCCCCCATTGCCAA GAAGGAGATCAGCCTGCCCATCCTCTGCAATGCCTCCAATGGCAGTGCCGTGGGCGTTCCTGACAGGACTGTCTCCAGGCTGGCCCAGGG CTCTCCAGCTGTGGCCAGGATTGCCCCTCAGCGGGCCCAGATCAGCTCCCCGAACCTACGGACAAGACCTCCACCACGCAGAGAATCCAG CCTGACATTCAAACGTGTTTTGATCAAAGAAGAGGAGTATGATTCTATTATAGTATTCTATAACTCGGTCTTCATGCAGAGACTGAAAAC AAATATTTTGCAGTATGCTTCCACCAGGCCCCCTACCTTGTCACCAATACCTCACATTCCTCGAAGCCCTTACAAGTTTCCTAGTTCACC CTTACGGATTCCTGGAGGGAACATCTATATTTCACCCCTGAAGAGTCCATATAAAATTTCAGAAGGTCTGCCAACACCAACAAAAATGAC TCCAAGATCAAGAATCTTAGTATCAATTGGTGAATCATTCGGGACTTCTGAGAAGTTCCAGAAAATAAATCAGATGGTATGTAACAGCGA CCGTGTGCTCAAAAGAAGTGCTGAAGGAAGCAACCCTCCTAAACCACTGAAAAAACTACGCTTTGATATTGAAGGATCAGATGAAGCAGA TGGAAGTAAACATCTCCCAGGAGAGTCCAAATTTCAGCAGAAACTGGCAGAAATGACTTCTACTCGAACACGAATGCAAAAGCAGAAAAT GAATGATAGCATGGATACCTCAAACAAGGAAGAGAAATGAGGATCTCAGGACCTTGGTGGACACTGTGTACACCTCTGGATTCATTGTCT CTCACAGATGTGACTGTATAACTTTCCCAGGTTCTGTTTATGGCCACATTTAATATCTTCAGCTCTTTTTGTGGATATAAAATGTGCAGA TGCAATTGTTTGGGTGATTCCTAAGCCACTTGAAATGTTAGTCATTGTTATTTATACAAGATTGAAAATCTTGTGTAAATCCTGCCATTT AAAAAGTTGTAGCAGATTGTTTCCTCTTCCAAAGTAAAATTGCTGTGCTTTATGGATAGTAAGAATGGCCCTAGAGTGGGAGTCCTGATA ACCCAGGCCTGTCTGACTACTTTGCCTTCTTTTGTAGCATATAGGTGATGTTTGCTCTTGTTTTTATTAATTTATATGTATATTTTTTTA ATTTAACATGAACACCCTTAGAAAATGTGTCCTATCTATCTTCCAAATGCAATTTGATTGACTGCCCATTCACCAAAATTATCCTGAACT CTTCTGCAAAAATGGATATTATTAGAAATTAGAAAAAAATTACTAATTTTACACATTAGATTTTATTTTACTATTGGAATCTGATATACT GTGTGCTTGTTTTATAAAATTTTGCTTTTAATTAAATAAAAGCTGGAAGCAAAGTATAACCATATGATACTATCATACTACTGAAACAGA TTTCATACCTCAGAATGTAAAAGAACTTACTGATTATTTTCTTCATCCAACTTATGTTTTTAAATGAGGATTATTGATAGTACTCTTGGT TTTTATACCATTCAGATCACTGAATTTATAAAGTACCCATCTAGTACTTGAAAAAGTAAAGTGTTCTGCCAGATCTTAGGTATAGAGGAC CCTAACACAGTATATCCCAAGTGCACTTTCTAATGTTTCTGGGTCCTGAAGAATTAAGATACAAATTAATTTTACTCCATAAACAGACTG TTAATTATAGGAGCCTTAATTTTTTTTTCATAGAGATTTGTCTAATTGCATCTCAAAATTATTCTGCCCTCCTTAATTTGGGAAGGTTTG TGTTTTCTCTGGAATGGTACATGTCTTCCATGTATCTTTTGAACTGGCAATTGTCTATTTATCTTTTATTTTTTTAAGTCAGTATGGTCT AACACTGGCATGTTCAAAGCCACATTATTTCTAGTCCAAAATTACAAGTAATCAAGGGTCATTATGGGTTAGGCATTAATGTTTCTATCT GATTTTGTGCAAAAGCTTCAAATTAAAACAGCTGCATTAGAAAAAGAGGCGCTTCTCCCCTCCCCTACACCTAAAGGTGTATTTAAACTA TCTTGTGTGATTAACTTATTTAGAGATGCTGTAACTTAAAATAGGGGATATTTAAGGTAGCTTCAGCTAGCTTTTAGGAAAATCACTTTG TCTAACTCAGAATTATTTTTAAAAAGAAATCTGGTCTTGTTAGAAAACAAAATTTTATTTTGTGCTCATTTAAGTTTCAAACTTACTATT TTGACAGTTATTTTGATAACAATGACACTAGAAAACTTGACTCCATTTCATCATTGTTTCTGCATGAATATCATACAAATCAGTTAGTTT TTAGGTCAAGGGCTTACTATTTCTGGGTCTTTTGCTACTAAGTTCACATTAGAATTAGTGCCAGAATTTTAGGAACTTCAGAGATCGTGT ATTGAGATTTCTTAAATAATGCTTCAGATATTATTGCTTTATTGCTTTTTTGTATTGGTTAAAACTGTACATTTAAAATTGCTATGTTAC TATTTTCTACAATTAATAGTTTGTCTATTTTAAAATAAATTAGTTGTTAAGAGTCTTAATGGTCTGATGTTGTGTTCTTTGTATTAAGTA >81514_81514_4_SH3PXD2A-RB1_SH3PXD2A_chr10_105371337_ENST00000538130_RB1_chr13_49039133_ENST00000267163_length(amino acids)=475AA_BP=284 MPFLSGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEVSK RRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKK NLAGPVEIIGNIMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLAQGSPAVARIAPQRAQISSP NLRTRPPPRRESSLTFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPY KISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQKLAE -------------------------------------------------------------- >81514_81514_5_SH3PXD2A-RB1_SH3PXD2A_chr10_105371337_ENST00000540321_RB1_chr13_49039133_ENST00000267163_length(transcript)=3411nt_BP=920nt AGACATTACACATGAACGGGTCGTTCCTGCTCCGGCTCCTGTTTCCTGTAGCGTCCATCCTGCCAGAGACTGTACTGCTTAGGGGTGCCG ACGCCACCGCCGAGCCCATGATCCTGGAACAGTACGTGGTGGTGTCCAACTATAAGAAGCAGGAGAACTCGGAGCTGAGCCTCCAGGCCG GGGAGGTGGTGGATGTCATCGAGAAGAACGAGAGCGGCTGGTGGTTCGTGAGCACTTCTGAGGAGCAGGGCTGGGTCCCTGCCACCTACC TGGAGGCCCAGAATGGTACTCGGGATGACTCCGACATCAACACCTCTAAGACTGGAGAAGTGTCCAAGAGACGCAAGGCCCATCTGCGGC GCCTGGATCGCCGGTGGACCCTGGGCGGGATGGTCAACAGGCAGCACAGCCGAGAGGAGAAGTATGTCACCGTGCAGCCTTACACCAGCC AAAGCAAGGACGAGATTGGCTTTGAGAAGGGCGTCACAGTGGAGGTGATCCGGAAGAATCTGGAAGGCTGGTGGTATATCAGATACCTGG GCAAAGAGGGCTGGGCGCCAGCATCCTACCTGAAGAAGGCCAAGGATGACCTGCCAACCCGGAAGAAGAACCTGGCCGGCCCAGTGGAGA TCATTGGGAACATCATGGAGATCAGCAACCTGCTGAACAAGAAGGCGTCTGGGGACAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATG AGGCCCCCATTGCCAAGAAGGAGATCAGCCTGCCCATCCTCTGCAATGCCTCCAATGGCAGTGCCGTGGGCGTTCCTGACAGGACTGTCT CCAGGCTGGCCCAGGGCTCTCCAGCTGTGGCCAGGATTGCCCCTCAGCGGGCCCAGATCAGCTCCCCGAACCTACGGACAAGACCTCCAC CACGCAGAGAATCCAGCCTGACATTCAAACGTGTTTTGATCAAAGAAGAGGAGTATGATTCTATTATAGTATTCTATAACTCGGTCTTCA TGCAGAGACTGAAAACAAATATTTTGCAGTATGCTTCCACCAGGCCCCCTACCTTGTCACCAATACCTCACATTCCTCGAAGCCCTTACA AGTTTCCTAGTTCACCCTTACGGATTCCTGGAGGGAACATCTATATTTCACCCCTGAAGAGTCCATATAAAATTTCAGAAGGTCTGCCAA CACCAACAAAAATGACTCCAAGATCAAGAATCTTAGTATCAATTGGTGAATCATTCGGGACTTCTGAGAAGTTCCAGAAAATAAATCAGA TGGTATGTAACAGCGACCGTGTGCTCAAAAGAAGTGCTGAAGGAAGCAACCCTCCTAAACCACTGAAAAAACTACGCTTTGATATTGAAG GATCAGATGAAGCAGATGGAAGTAAACATCTCCCAGGAGAGTCCAAATTTCAGCAGAAACTGGCAGAAATGACTTCTACTCGAACACGAA TGCAAAAGCAGAAAATGAATGATAGCATGGATACCTCAAACAAGGAAGAGAAATGAGGATCTCAGGACCTTGGTGGACACTGTGTACACC TCTGGATTCATTGTCTCTCACAGATGTGACTGTATAACTTTCCCAGGTTCTGTTTATGGCCACATTTAATATCTTCAGCTCTTTTTGTGG ATATAAAATGTGCAGATGCAATTGTTTGGGTGATTCCTAAGCCACTTGAAATGTTAGTCATTGTTATTTATACAAGATTGAAAATCTTGT GTAAATCCTGCCATTTAAAAAGTTGTAGCAGATTGTTTCCTCTTCCAAAGTAAAATTGCTGTGCTTTATGGATAGTAAGAATGGCCCTAG AGTGGGAGTCCTGATAACCCAGGCCTGTCTGACTACTTTGCCTTCTTTTGTAGCATATAGGTGATGTTTGCTCTTGTTTTTATTAATTTA TATGTATATTTTTTTAATTTAACATGAACACCCTTAGAAAATGTGTCCTATCTATCTTCCAAATGCAATTTGATTGACTGCCCATTCACC AAAATTATCCTGAACTCTTCTGCAAAAATGGATATTATTAGAAATTAGAAAAAAATTACTAATTTTACACATTAGATTTTATTTTACTAT TGGAATCTGATATACTGTGTGCTTGTTTTATAAAATTTTGCTTTTAATTAAATAAAAGCTGGAAGCAAAGTATAACCATATGATACTATC ATACTACTGAAACAGATTTCATACCTCAGAATGTAAAAGAACTTACTGATTATTTTCTTCATCCAACTTATGTTTTTAAATGAGGATTAT TGATAGTACTCTTGGTTTTTATACCATTCAGATCACTGAATTTATAAAGTACCCATCTAGTACTTGAAAAAGTAAAGTGTTCTGCCAGAT CTTAGGTATAGAGGACCCTAACACAGTATATCCCAAGTGCACTTTCTAATGTTTCTGGGTCCTGAAGAATTAAGATACAAATTAATTTTA CTCCATAAACAGACTGTTAATTATAGGAGCCTTAATTTTTTTTTCATAGAGATTTGTCTAATTGCATCTCAAAATTATTCTGCCCTCCTT AATTTGGGAAGGTTTGTGTTTTCTCTGGAATGGTACATGTCTTCCATGTATCTTTTGAACTGGCAATTGTCTATTTATCTTTTATTTTTT TAAGTCAGTATGGTCTAACACTGGCATGTTCAAAGCCACATTATTTCTAGTCCAAAATTACAAGTAATCAAGGGTCATTATGGGTTAGGC ATTAATGTTTCTATCTGATTTTGTGCAAAAGCTTCAAATTAAAACAGCTGCATTAGAAAAAGAGGCGCTTCTCCCCTCCCCTACACCTAA AGGTGTATTTAAACTATCTTGTGTGATTAACTTATTTAGAGATGCTGTAACTTAAAATAGGGGATATTTAAGGTAGCTTCAGCTAGCTTT TAGGAAAATCACTTTGTCTAACTCAGAATTATTTTTAAAAAGAAATCTGGTCTTGTTAGAAAACAAAATTTTATTTTGTGCTCATTTAAG TTTCAAACTTACTATTTTGACAGTTATTTTGATAACAATGACACTAGAAAACTTGACTCCATTTCATCATTGTTTCTGCATGAATATCAT ACAAATCAGTTAGTTTTTAGGTCAAGGGCTTACTATTTCTGGGTCTTTTGCTACTAAGTTCACATTAGAATTAGTGCCAGAATTTTAGGA ACTTCAGAGATCGTGTATTGAGATTTCTTAAATAATGCTTCAGATATTATTGCTTTATTGCTTTTTTGTATTGGTTAAAACTGTACATTT AAAATTGCTATGTTACTATTTTCTACAATTAATAGTTTGTCTATTTTAAAATAAATTAGTTGTTAAGAGTCTTAATGGTCTGATGTTGTG >81514_81514_5_SH3PXD2A-RB1_SH3PXD2A_chr10_105371337_ENST00000540321_RB1_chr13_49039133_ENST00000267163_length(amino acids)=494AA_BP=303 MNGSFLLRLLFPVASILPETVLLRGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQ NGTRDDSDINTSKTGEVSKRRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEG WAPASYLKKAKDDLPTRKKNLAGPVEIIGNIMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLA QGSPAVARIAPQRAQISSPNLRTRPPPRRESSLTFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPS SPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDE -------------------------------------------------------------- >81514_81514_6_SH3PXD2A-RB1_SH3PXD2A_chr10_105371338_ENST00000355946_RB1_chr13_49039134_ENST00000267163_length(transcript)=3855nt_BP=1364nt CCGGGAGTCCGGGCAGCGTTCGGCGCGCCGGGCCGGGGTGGCGGGCGGCCCCGGGACCCCGGCAGCTGGAGAAGGAGCCGGAGCCCGGCC GGGATGAGAAGGTGACGCCGCCGGGGGCGCCACTCGCTTTGTGGGGGAAGATGCTCGCCTACTGCGTGCAGGATGCCACCGTGGTGGACG TGGAGAAGCGGAGGAACCCCTCCAAGCACTACGTATACATAATCAATGTGACCTGGTCTGACTCCACCTCCCAGACTATCTACCGGAGGT ACAGCAAGTTCTTTGACCTGCAGATGCAGCTTTTGGATAAGTTTCCCATTGAAGGTGGCCAGAAGGACCCCAAGCAAAGGATCATCCCCT TCCTCCCAGGCAAGATCCTCTTCCGCAGAAGCCACATCCGGGACGTAGCTGTGAAGAGACTGAAGCCCATCGATGAATACTGCCGGGCAC TTGTCCGGCTGCCCCCCCACATCTCACAGTGTGACGAAGTCTTCCGGTTCTTCGAGGCTCGACCCGAGGATGTCAACCCTCCAAAAGAGG ACTATGGCAGTTCCAAGAGGAAATCAGTGTGGCTGTCCAGCTGGGCTGAGTCGCCCAAGAAGGACGTGACAGGTGCCGACGCCACCGCCG AGCCCATGATCCTGGAACAGTACGTGGTGGTGTCCAACTATAAGAAGCAGGAGAACTCGGAGCTGAGCCTCCAGGCCGGGGAGGTGGTGG ATGTCATCGAGAAGAACGAGAGCGGCTGGTGGTTCGTGAGCACTTCTGAGGAGCAGGGCTGGGTCCCTGCCACCTACCTGGAGGCCCAGA ATGGTACTCGGGATGACTCCGACATCAACACCTCTAAGACTGGAGAAGAGGAGAAGTATGTCACCGTGCAGCCTTACACCAGCCAAAGCA AGGACGAGATTGGCTTTGAGAAGGGCGTCACAGTGGAGGTGATCCGGAAGAATCTGGAAGGCTGGTGGTATATCAGATACCTGGGCAAAG AGGGCTGGGCGCCAGCATCCTACCTGAAGAAGGCCAAGGATGACCTGCCAACCCGGAAGAAGAACCTGGCCGGCCCAGTGGAGATCATTG GGAACATCATGGAGATCAGCAACCTGCTGAACAAGAAGGCGTCTGGGGACAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATGAGGCCC CCATTGCCAAGAAGGAGATCAGCCTGCCCATCCTCTGCAATGCCTCCAATGGCAGTGCCGTGGGCGTTCCTGACAGGACTGTCTCCAGGC TGGCCCAGGGCTCTCCAGCTGTGGCCAGGATTGCCCCTCAGCGGGCCCAGATCAGCTCCCCGAACCTACGGACAAGACCTCCACCACGCA GAGAATCCAGCCTGACATTCAAACGTGTTTTGATCAAAGAAGAGGAGTATGATTCTATTATAGTATTCTATAACTCGGTCTTCATGCAGA GACTGAAAACAAATATTTTGCAGTATGCTTCCACCAGGCCCCCTACCTTGTCACCAATACCTCACATTCCTCGAAGCCCTTACAAGTTTC CTAGTTCACCCTTACGGATTCCTGGAGGGAACATCTATATTTCACCCCTGAAGAGTCCATATAAAATTTCAGAAGGTCTGCCAACACCAA CAAAAATGACTCCAAGATCAAGAATCTTAGTATCAATTGGTGAATCATTCGGGACTTCTGAGAAGTTCCAGAAAATAAATCAGATGGTAT GTAACAGCGACCGTGTGCTCAAAAGAAGTGCTGAAGGAAGCAACCCTCCTAAACCACTGAAAAAACTACGCTTTGATATTGAAGGATCAG ATGAAGCAGATGGAAGTAAACATCTCCCAGGAGAGTCCAAATTTCAGCAGAAACTGGCAGAAATGACTTCTACTCGAACACGAATGCAAA AGCAGAAAATGAATGATAGCATGGATACCTCAAACAAGGAAGAGAAATGAGGATCTCAGGACCTTGGTGGACACTGTGTACACCTCTGGA TTCATTGTCTCTCACAGATGTGACTGTATAACTTTCCCAGGTTCTGTTTATGGCCACATTTAATATCTTCAGCTCTTTTTGTGGATATAA AATGTGCAGATGCAATTGTTTGGGTGATTCCTAAGCCACTTGAAATGTTAGTCATTGTTATTTATACAAGATTGAAAATCTTGTGTAAAT CCTGCCATTTAAAAAGTTGTAGCAGATTGTTTCCTCTTCCAAAGTAAAATTGCTGTGCTTTATGGATAGTAAGAATGGCCCTAGAGTGGG AGTCCTGATAACCCAGGCCTGTCTGACTACTTTGCCTTCTTTTGTAGCATATAGGTGATGTTTGCTCTTGTTTTTATTAATTTATATGTA TATTTTTTTAATTTAACATGAACACCCTTAGAAAATGTGTCCTATCTATCTTCCAAATGCAATTTGATTGACTGCCCATTCACCAAAATT ATCCTGAACTCTTCTGCAAAAATGGATATTATTAGAAATTAGAAAAAAATTACTAATTTTACACATTAGATTTTATTTTACTATTGGAAT CTGATATACTGTGTGCTTGTTTTATAAAATTTTGCTTTTAATTAAATAAAAGCTGGAAGCAAAGTATAACCATATGATACTATCATACTA CTGAAACAGATTTCATACCTCAGAATGTAAAAGAACTTACTGATTATTTTCTTCATCCAACTTATGTTTTTAAATGAGGATTATTGATAG TACTCTTGGTTTTTATACCATTCAGATCACTGAATTTATAAAGTACCCATCTAGTACTTGAAAAAGTAAAGTGTTCTGCCAGATCTTAGG TATAGAGGACCCTAACACAGTATATCCCAAGTGCACTTTCTAATGTTTCTGGGTCCTGAAGAATTAAGATACAAATTAATTTTACTCCAT AAACAGACTGTTAATTATAGGAGCCTTAATTTTTTTTTCATAGAGATTTGTCTAATTGCATCTCAAAATTATTCTGCCCTCCTTAATTTG GGAAGGTTTGTGTTTTCTCTGGAATGGTACATGTCTTCCATGTATCTTTTGAACTGGCAATTGTCTATTTATCTTTTATTTTTTTAAGTC AGTATGGTCTAACACTGGCATGTTCAAAGCCACATTATTTCTAGTCCAAAATTACAAGTAATCAAGGGTCATTATGGGTTAGGCATTAAT GTTTCTATCTGATTTTGTGCAAAAGCTTCAAATTAAAACAGCTGCATTAGAAAAAGAGGCGCTTCTCCCCTCCCCTACACCTAAAGGTGT ATTTAAACTATCTTGTGTGATTAACTTATTTAGAGATGCTGTAACTTAAAATAGGGGATATTTAAGGTAGCTTCAGCTAGCTTTTAGGAA AATCACTTTGTCTAACTCAGAATTATTTTTAAAAAGAAATCTGGTCTTGTTAGAAAACAAAATTTTATTTTGTGCTCATTTAAGTTTCAA ACTTACTATTTTGACAGTTATTTTGATAACAATGACACTAGAAAACTTGACTCCATTTCATCATTGTTTCTGCATGAATATCATACAAAT CAGTTAGTTTTTAGGTCAAGGGCTTACTATTTCTGGGTCTTTTGCTACTAAGTTCACATTAGAATTAGTGCCAGAATTTTAGGAACTTCA GAGATCGTGTATTGAGATTTCTTAAATAATGCTTCAGATATTATTGCTTTATTGCTTTTTTGTATTGGTTAAAACTGTACATTTAAAATT GCTATGTTACTATTTTCTACAATTAATAGTTTGTCTATTTTAAAATAAATTAGTTGTTAAGAGTCTTAATGGTCTGATGTTGTGTTCTTT >81514_81514_6_SH3PXD2A-RB1_SH3PXD2A_chr10_105371338_ENST00000355946_RB1_chr13_49039134_ENST00000267163_length(amino acids)=624AA_BP=433 MEKEPEPGRDEKVTPPGAPLALWGKMLAYCVQDATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQK DPKQRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKD VTGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEEEKYVT VQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKKNLAGPVEIIGNIMEISNLLNKKASGDKETPP AEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLAQGSPAVARIAPQRAQISSPNLRTRPPPRRESSLTFKRVLIKEEEYDSIIV FYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEK -------------------------------------------------------------- >81514_81514_7_SH3PXD2A-RB1_SH3PXD2A_chr10_105371338_ENST00000369774_RB1_chr13_49039134_ENST00000267163_length(transcript)=4076nt_BP=1585nt GCGAGCGGGCGAGCGCAGCGCGGCGGCCGCGCGGGAGTGAAGGGGCGCGCGGCAGGCCGGCGGGGAGTCCCCCGGGGCGCACGGAGCCCG CGCGCCCTCCGGGACCCTCCCCCGTCCCTGGGCCGGACCTGTGGGCGCCGGGAGTCCGGGCAGCGTTCGGCGCGCCGGGCCGGGGTGGCG GGCGGCCCCGGGACCCCGGCAGCTGGAGAAGGAGCCGGAGCCCGGCCGGGATGAGAAGGTGACGCCGCCGGGGGCGCCACTCGCTTTGTG GGGGAAGATGCTCGCCTACTGCGTGCAGGATGCCACCGTGGTGGACGTGGAGAAGCGGAGGAACCCCTCCAAGCACTACGTATACATAAT CAATGTGACCTGGTCTGACTCCACCTCCCAGACTATCTACCGGAGGTACAGCAAGTTCTTTGACCTGCAGATGCAGCTTTTGGATAAGTT TCCCATTGAAGGTGGCCAGAAGGACCCCAAGCAAAGGATCATCCCCTTCCTCCCAGGCAAGATCCTCTTCCGCAGAAGCCACATCCGGGA CGTAGCTGTGAAGAGACTGAAGCCCATCGATGAATACTGCCGGGCACTTGTCCGGCTGCCCCCCCACATCTCACAGTGTGACGAAGTCTT CCGGTTCTTCGAGGCTCGACCCGAGGATGTCAACCCTCCAAAAGAGGACTATGGCAGTTCCAAGAGGAAATCAGTGTGGCTGTCCAGCTG GGCTGAGTCGCCCAAGAAGGACGTGACAGGTGCCGACGCCACCGCCGAGCCCATGATCCTGGAACAGTACGTGGTGGTGTCCAACTATAA GAAGCAGGAGAACTCGGAGCTGAGCCTCCAGGCCGGGGAGGTGGTGGATGTCATCGAGAAGAACGAGAGCGGCTGGTGGTTCGTGAGCAC TTCTGAGGAGCAGGGCTGGGTCCCTGCCACCTACCTGGAGGCCCAGAATGGTACTCGGGATGACTCCGACATCAACACCTCTAAGACTGG AGAAGTGTCCAAGAGACGCAAGGCCCATCTGCGGCGCCTGGATCGCCGGTGGACCCTGGGCGGGATGGTCAACAGGCAGCACAGCCGAGA GGAGAAGTATGTCACCGTGCAGCCTTACACCAGCCAAAGCAAGGACGAGATTGGCTTTGAGAAGGGCGTCACAGTGGAGGTGATCCGGAA GAATCTGGAAGGCTGGTGGTATATCAGATACCTGGGCAAAGAGGGCTGGGCGCCAGCATCCTACCTGAAGAAGGCCAAGGATGACCTGCC AACCCGGAAGAAGAACCTGGCCGGCCCAGTGGAGATCATTGGGAACATCATGGAGATCAGCAACCTGCTGAACAAGAAGGCGTCTGGGGA CAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATGAGGCCCCCATTGCCAAGAAGGAGATCAGCCTGCCCATCCTCTGCAATGCCTCCAA TGGCAGTGCCGTGGGCGTTCCTGACAGGACTGTCTCCAGGCTGGCCCAGGGCTCTCCAGCTGTGGCCAGGATTGCCCCTCAGCGGGCCCA GATCAGCTCCCCGAACCTACGGACAAGACCTCCACCACGCAGAGAATCCAGCCTGACATTCAAACGTGTTTTGATCAAAGAAGAGGAGTA TGATTCTATTATAGTATTCTATAACTCGGTCTTCATGCAGAGACTGAAAACAAATATTTTGCAGTATGCTTCCACCAGGCCCCCTACCTT GTCACCAATACCTCACATTCCTCGAAGCCCTTACAAGTTTCCTAGTTCACCCTTACGGATTCCTGGAGGGAACATCTATATTTCACCCCT GAAGAGTCCATATAAAATTTCAGAAGGTCTGCCAACACCAACAAAAATGACTCCAAGATCAAGAATCTTAGTATCAATTGGTGAATCATT CGGGACTTCTGAGAAGTTCCAGAAAATAAATCAGATGGTATGTAACAGCGACCGTGTGCTCAAAAGAAGTGCTGAAGGAAGCAACCCTCC TAAACCACTGAAAAAACTACGCTTTGATATTGAAGGATCAGATGAAGCAGATGGAAGTAAACATCTCCCAGGAGAGTCCAAATTTCAGCA GAAACTGGCAGAAATGACTTCTACTCGAACACGAATGCAAAAGCAGAAAATGAATGATAGCATGGATACCTCAAACAAGGAAGAGAAATG AGGATCTCAGGACCTTGGTGGACACTGTGTACACCTCTGGATTCATTGTCTCTCACAGATGTGACTGTATAACTTTCCCAGGTTCTGTTT ATGGCCACATTTAATATCTTCAGCTCTTTTTGTGGATATAAAATGTGCAGATGCAATTGTTTGGGTGATTCCTAAGCCACTTGAAATGTT AGTCATTGTTATTTATACAAGATTGAAAATCTTGTGTAAATCCTGCCATTTAAAAAGTTGTAGCAGATTGTTTCCTCTTCCAAAGTAAAA TTGCTGTGCTTTATGGATAGTAAGAATGGCCCTAGAGTGGGAGTCCTGATAACCCAGGCCTGTCTGACTACTTTGCCTTCTTTTGTAGCA TATAGGTGATGTTTGCTCTTGTTTTTATTAATTTATATGTATATTTTTTTAATTTAACATGAACACCCTTAGAAAATGTGTCCTATCTAT CTTCCAAATGCAATTTGATTGACTGCCCATTCACCAAAATTATCCTGAACTCTTCTGCAAAAATGGATATTATTAGAAATTAGAAAAAAA TTACTAATTTTACACATTAGATTTTATTTTACTATTGGAATCTGATATACTGTGTGCTTGTTTTATAAAATTTTGCTTTTAATTAAATAA AAGCTGGAAGCAAAGTATAACCATATGATACTATCATACTACTGAAACAGATTTCATACCTCAGAATGTAAAAGAACTTACTGATTATTT TCTTCATCCAACTTATGTTTTTAAATGAGGATTATTGATAGTACTCTTGGTTTTTATACCATTCAGATCACTGAATTTATAAAGTACCCA TCTAGTACTTGAAAAAGTAAAGTGTTCTGCCAGATCTTAGGTATAGAGGACCCTAACACAGTATATCCCAAGTGCACTTTCTAATGTTTC TGGGTCCTGAAGAATTAAGATACAAATTAATTTTACTCCATAAACAGACTGTTAATTATAGGAGCCTTAATTTTTTTTTCATAGAGATTT GTCTAATTGCATCTCAAAATTATTCTGCCCTCCTTAATTTGGGAAGGTTTGTGTTTTCTCTGGAATGGTACATGTCTTCCATGTATCTTT TGAACTGGCAATTGTCTATTTATCTTTTATTTTTTTAAGTCAGTATGGTCTAACACTGGCATGTTCAAAGCCACATTATTTCTAGTCCAA AATTACAAGTAATCAAGGGTCATTATGGGTTAGGCATTAATGTTTCTATCTGATTTTGTGCAAAAGCTTCAAATTAAAACAGCTGCATTA GAAAAAGAGGCGCTTCTCCCCTCCCCTACACCTAAAGGTGTATTTAAACTATCTTGTGTGATTAACTTATTTAGAGATGCTGTAACTTAA AATAGGGGATATTTAAGGTAGCTTCAGCTAGCTTTTAGGAAAATCACTTTGTCTAACTCAGAATTATTTTTAAAAAGAAATCTGGTCTTG TTAGAAAACAAAATTTTATTTTGTGCTCATTTAAGTTTCAAACTTACTATTTTGACAGTTATTTTGATAACAATGACACTAGAAAACTTG ACTCCATTTCATCATTGTTTCTGCATGAATATCATACAAATCAGTTAGTTTTTAGGTCAAGGGCTTACTATTTCTGGGTCTTTTGCTACT AAGTTCACATTAGAATTAGTGCCAGAATTTTAGGAACTTCAGAGATCGTGTATTGAGATTTCTTAAATAATGCTTCAGATATTATTGCTT TATTGCTTTTTTGTATTGGTTAAAACTGTACATTTAAAATTGCTATGTTACTATTTTCTACAATTAATAGTTTGTCTATTTTAAAATAAA TTAGTTGTTAAGAGTCTTAATGGTCTGATGTTGTGTTCTTTGTATTAAGTACACTAATGTTCTCTTTTCTGTCTAGGAGAAGATAGATAG >81514_81514_7_SH3PXD2A-RB1_SH3PXD2A_chr10_105371338_ENST00000369774_RB1_chr13_49039134_ENST00000267163_length(amino acids)=652AA_BP=461 MEKEPEPGRDEKVTPPGAPLALWGKMLAYCVQDATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQK DPKQRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKD VTGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEVSKRRK AHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKKNLA GPVEIIGNIMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLAQGSPAVARIAPQRAQISSPNLR TRPPPRRESSLTFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKIS EGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQKLAEMTS -------------------------------------------------------------- >81514_81514_8_SH3PXD2A-RB1_SH3PXD2A_chr10_105371338_ENST00000427662_RB1_chr13_49039134_ENST00000267163_length(transcript)=3472nt_BP=981nt ACATGAGCAGCGGCACCGGGGACCGACCGCAGCCAGCCCGAGGGCGCCCCTGCAGCTGCAGCCCCGCGCTCGCGCCCGGCCCTAACCATG TCTATCTGTTGTTGCTTCTTTTTCAGGGACTATGGCAGTTCCAAGAGGAAATCAGGTGCCGACGCCACCGCCGAGCCCATGATCCTGGAA CAGTACGTGGTGGTGTCCAACTATAAGAAGCAGGAGAACTCGGAGCTGAGCCTCCAGGCCGGGGAGGTGGTGGATGTCATCGAGAAGAAC GAGAGCGGCTGGTGGTTCGTGAGCACTTCTGAGGAGCAGGGCTGGGTCCCTGCCACCTACCTGGAGGCCCAGAATGGTACTCGGGATGAC TCCGACATCAACACCTCTAAGACTGGAGAAGTGTCCAAGAGACGCAAGGCCCATCTGCGGCGCCTGGATCGCCGGTGGACCCTGGGCGGG ATGGTCAACAGGCAGCACAGCCGAGAGGAGAAGTATGTCACCGTGCAGCCTTACACCAGCCAAAGCAAGGACGAGATTGGCTTTGAGAAG GGCGTCACAGTGGAGGTGATCCGGAAGAATCTGGAAGGCTGGTGGTATATCAGATACCTGGGCAAAGAGGGCTGGGCGCCAGCATCCTAC CTGAAGAAGGCCAAGGATGACCTGCCAACCCGGAAGAAGAACCTGGCCGGCCCAGTGGAGATCATTGGGAACATCATGGAGATCAGCAAC CTGCTGAACAAGAAGGCGTCTGGGGACAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATGAGGCCCCCATTGCCAAGAAGGAGATCAGC CTGCCCATCCTCTGCAATGCCTCCAATGGCAGTGCCGTGGGCGTTCCTGACAGGACTGTCTCCAGGCTGGCCCAGGGCTCTCCAGCTGTG GCCAGGATTGCCCCTCAGCGGGCCCAGATCAGCTCCCCGAACCTACGGACAAGACCTCCACCACGCAGAGAATCCAGCCTGACATTCAAA CGTGTTTTGATCAAAGAAGAGGAGTATGATTCTATTATAGTATTCTATAACTCGGTCTTCATGCAGAGACTGAAAACAAATATTTTGCAG TATGCTTCCACCAGGCCCCCTACCTTGTCACCAATACCTCACATTCCTCGAAGCCCTTACAAGTTTCCTAGTTCACCCTTACGGATTCCT GGAGGGAACATCTATATTTCACCCCTGAAGAGTCCATATAAAATTTCAGAAGGTCTGCCAACACCAACAAAAATGACTCCAAGATCAAGA ATCTTAGTATCAATTGGTGAATCATTCGGGACTTCTGAGAAGTTCCAGAAAATAAATCAGATGGTATGTAACAGCGACCGTGTGCTCAAA AGAAGTGCTGAAGGAAGCAACCCTCCTAAACCACTGAAAAAACTACGCTTTGATATTGAAGGATCAGATGAAGCAGATGGAAGTAAACAT CTCCCAGGAGAGTCCAAATTTCAGCAGAAACTGGCAGAAATGACTTCTACTCGAACACGAATGCAAAAGCAGAAAATGAATGATAGCATG GATACCTCAAACAAGGAAGAGAAATGAGGATCTCAGGACCTTGGTGGACACTGTGTACACCTCTGGATTCATTGTCTCTCACAGATGTGA CTGTATAACTTTCCCAGGTTCTGTTTATGGCCACATTTAATATCTTCAGCTCTTTTTGTGGATATAAAATGTGCAGATGCAATTGTTTGG GTGATTCCTAAGCCACTTGAAATGTTAGTCATTGTTATTTATACAAGATTGAAAATCTTGTGTAAATCCTGCCATTTAAAAAGTTGTAGC AGATTGTTTCCTCTTCCAAAGTAAAATTGCTGTGCTTTATGGATAGTAAGAATGGCCCTAGAGTGGGAGTCCTGATAACCCAGGCCTGTC TGACTACTTTGCCTTCTTTTGTAGCATATAGGTGATGTTTGCTCTTGTTTTTATTAATTTATATGTATATTTTTTTAATTTAACATGAAC ACCCTTAGAAAATGTGTCCTATCTATCTTCCAAATGCAATTTGATTGACTGCCCATTCACCAAAATTATCCTGAACTCTTCTGCAAAAAT GGATATTATTAGAAATTAGAAAAAAATTACTAATTTTACACATTAGATTTTATTTTACTATTGGAATCTGATATACTGTGTGCTTGTTTT ATAAAATTTTGCTTTTAATTAAATAAAAGCTGGAAGCAAAGTATAACCATATGATACTATCATACTACTGAAACAGATTTCATACCTCAG AATGTAAAAGAACTTACTGATTATTTTCTTCATCCAACTTATGTTTTTAAATGAGGATTATTGATAGTACTCTTGGTTTTTATACCATTC AGATCACTGAATTTATAAAGTACCCATCTAGTACTTGAAAAAGTAAAGTGTTCTGCCAGATCTTAGGTATAGAGGACCCTAACACAGTAT ATCCCAAGTGCACTTTCTAATGTTTCTGGGTCCTGAAGAATTAAGATACAAATTAATTTTACTCCATAAACAGACTGTTAATTATAGGAG CCTTAATTTTTTTTTCATAGAGATTTGTCTAATTGCATCTCAAAATTATTCTGCCCTCCTTAATTTGGGAAGGTTTGTGTTTTCTCTGGA ATGGTACATGTCTTCCATGTATCTTTTGAACTGGCAATTGTCTATTTATCTTTTATTTTTTTAAGTCAGTATGGTCTAACACTGGCATGT TCAAAGCCACATTATTTCTAGTCCAAAATTACAAGTAATCAAGGGTCATTATGGGTTAGGCATTAATGTTTCTATCTGATTTTGTGCAAA AGCTTCAAATTAAAACAGCTGCATTAGAAAAAGAGGCGCTTCTCCCCTCCCCTACACCTAAAGGTGTATTTAAACTATCTTGTGTGATTA ACTTATTTAGAGATGCTGTAACTTAAAATAGGGGATATTTAAGGTAGCTTCAGCTAGCTTTTAGGAAAATCACTTTGTCTAACTCAGAAT TATTTTTAAAAAGAAATCTGGTCTTGTTAGAAAACAAAATTTTATTTTGTGCTCATTTAAGTTTCAAACTTACTATTTTGACAGTTATTT TGATAACAATGACACTAGAAAACTTGACTCCATTTCATCATTGTTTCTGCATGAATATCATACAAATCAGTTAGTTTTTAGGTCAAGGGC TTACTATTTCTGGGTCTTTTGCTACTAAGTTCACATTAGAATTAGTGCCAGAATTTTAGGAACTTCAGAGATCGTGTATTGAGATTTCTT AAATAATGCTTCAGATATTATTGCTTTATTGCTTTTTTGTATTGGTTAAAACTGTACATTTAAAATTGCTATGTTACTATTTTCTACAAT TAATAGTTTGTCTATTTTAAAATAAATTAGTTGTTAAGAGTCTTAATGGTCTGATGTTGTGTTCTTTGTATTAAGTACACTAATGTTCTC >81514_81514_8_SH3PXD2A-RB1_SH3PXD2A_chr10_105371338_ENST00000427662_RB1_chr13_49039134_ENST00000267163_length(amino acids)=489AA_BP=298 MSICCCFFFRDYGSSKRKSGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRD DSDINTSKTGEVSKRRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPAS YLKKAKDDLPTRKKNLAGPVEIIGNIMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLAQGSPA VARIAPQRAQISSPNLRTRPPPRRESSLTFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRI PGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSK -------------------------------------------------------------- >81514_81514_9_SH3PXD2A-RB1_SH3PXD2A_chr10_105371338_ENST00000538130_RB1_chr13_49039134_ENST00000267163_length(transcript)=3395nt_BP=904nt GAGAAGCTCTCTCCCGCTCTCTCCTCTCCCTCTCCCGCCCGAGGGAGCAGGGCTGCCTTTTCTCTCGGGTGCCGACGCCACCGCCGAGCC CATGATCCTGGAACAGTACGTGGTGGTGTCCAACTATAAGAAGCAGGAGAACTCGGAGCTGAGCCTCCAGGCCGGGGAGGTGGTGGATGT CATCGAGAAGAACGAGAGCGGCTGGTGGTTCGTGAGCACTTCTGAGGAGCAGGGCTGGGTCCCTGCCACCTACCTGGAGGCCCAGAATGG TACTCGGGATGACTCCGACATCAACACCTCTAAGACTGGAGAAGTGTCCAAGAGACGCAAGGCCCATCTGCGGCGCCTGGATCGCCGGTG GACCCTGGGCGGGATGGTCAACAGGCAGCACAGCCGAGAGGAGAAGTATGTCACCGTGCAGCCTTACACCAGCCAAAGCAAGGACGAGAT TGGCTTTGAGAAGGGCGTCACAGTGGAGGTGATCCGGAAGAATCTGGAAGGCTGGTGGTATATCAGATACCTGGGCAAAGAGGGCTGGGC GCCAGCATCCTACCTGAAGAAGGCCAAGGATGACCTGCCAACCCGGAAGAAGAACCTGGCCGGCCCAGTGGAGATCATTGGGAACATCAT GGAGATCAGCAACCTGCTGAACAAGAAGGCGTCTGGGGACAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATGAGGCCCCCATTGCCAA GAAGGAGATCAGCCTGCCCATCCTCTGCAATGCCTCCAATGGCAGTGCCGTGGGCGTTCCTGACAGGACTGTCTCCAGGCTGGCCCAGGG CTCTCCAGCTGTGGCCAGGATTGCCCCTCAGCGGGCCCAGATCAGCTCCCCGAACCTACGGACAAGACCTCCACCACGCAGAGAATCCAG CCTGACATTCAAACGTGTTTTGATCAAAGAAGAGGAGTATGATTCTATTATAGTATTCTATAACTCGGTCTTCATGCAGAGACTGAAAAC AAATATTTTGCAGTATGCTTCCACCAGGCCCCCTACCTTGTCACCAATACCTCACATTCCTCGAAGCCCTTACAAGTTTCCTAGTTCACC CTTACGGATTCCTGGAGGGAACATCTATATTTCACCCCTGAAGAGTCCATATAAAATTTCAGAAGGTCTGCCAACACCAACAAAAATGAC TCCAAGATCAAGAATCTTAGTATCAATTGGTGAATCATTCGGGACTTCTGAGAAGTTCCAGAAAATAAATCAGATGGTATGTAACAGCGA CCGTGTGCTCAAAAGAAGTGCTGAAGGAAGCAACCCTCCTAAACCACTGAAAAAACTACGCTTTGATATTGAAGGATCAGATGAAGCAGA TGGAAGTAAACATCTCCCAGGAGAGTCCAAATTTCAGCAGAAACTGGCAGAAATGACTTCTACTCGAACACGAATGCAAAAGCAGAAAAT GAATGATAGCATGGATACCTCAAACAAGGAAGAGAAATGAGGATCTCAGGACCTTGGTGGACACTGTGTACACCTCTGGATTCATTGTCT CTCACAGATGTGACTGTATAACTTTCCCAGGTTCTGTTTATGGCCACATTTAATATCTTCAGCTCTTTTTGTGGATATAAAATGTGCAGA TGCAATTGTTTGGGTGATTCCTAAGCCACTTGAAATGTTAGTCATTGTTATTTATACAAGATTGAAAATCTTGTGTAAATCCTGCCATTT AAAAAGTTGTAGCAGATTGTTTCCTCTTCCAAAGTAAAATTGCTGTGCTTTATGGATAGTAAGAATGGCCCTAGAGTGGGAGTCCTGATA ACCCAGGCCTGTCTGACTACTTTGCCTTCTTTTGTAGCATATAGGTGATGTTTGCTCTTGTTTTTATTAATTTATATGTATATTTTTTTA ATTTAACATGAACACCCTTAGAAAATGTGTCCTATCTATCTTCCAAATGCAATTTGATTGACTGCCCATTCACCAAAATTATCCTGAACT CTTCTGCAAAAATGGATATTATTAGAAATTAGAAAAAAATTACTAATTTTACACATTAGATTTTATTTTACTATTGGAATCTGATATACT GTGTGCTTGTTTTATAAAATTTTGCTTTTAATTAAATAAAAGCTGGAAGCAAAGTATAACCATATGATACTATCATACTACTGAAACAGA TTTCATACCTCAGAATGTAAAAGAACTTACTGATTATTTTCTTCATCCAACTTATGTTTTTAAATGAGGATTATTGATAGTACTCTTGGT TTTTATACCATTCAGATCACTGAATTTATAAAGTACCCATCTAGTACTTGAAAAAGTAAAGTGTTCTGCCAGATCTTAGGTATAGAGGAC CCTAACACAGTATATCCCAAGTGCACTTTCTAATGTTTCTGGGTCCTGAAGAATTAAGATACAAATTAATTTTACTCCATAAACAGACTG TTAATTATAGGAGCCTTAATTTTTTTTTCATAGAGATTTGTCTAATTGCATCTCAAAATTATTCTGCCCTCCTTAATTTGGGAAGGTTTG TGTTTTCTCTGGAATGGTACATGTCTTCCATGTATCTTTTGAACTGGCAATTGTCTATTTATCTTTTATTTTTTTAAGTCAGTATGGTCT AACACTGGCATGTTCAAAGCCACATTATTTCTAGTCCAAAATTACAAGTAATCAAGGGTCATTATGGGTTAGGCATTAATGTTTCTATCT GATTTTGTGCAAAAGCTTCAAATTAAAACAGCTGCATTAGAAAAAGAGGCGCTTCTCCCCTCCCCTACACCTAAAGGTGTATTTAAACTA TCTTGTGTGATTAACTTATTTAGAGATGCTGTAACTTAAAATAGGGGATATTTAAGGTAGCTTCAGCTAGCTTTTAGGAAAATCACTTTG TCTAACTCAGAATTATTTTTAAAAAGAAATCTGGTCTTGTTAGAAAACAAAATTTTATTTTGTGCTCATTTAAGTTTCAAACTTACTATT TTGACAGTTATTTTGATAACAATGACACTAGAAAACTTGACTCCATTTCATCATTGTTTCTGCATGAATATCATACAAATCAGTTAGTTT TTAGGTCAAGGGCTTACTATTTCTGGGTCTTTTGCTACTAAGTTCACATTAGAATTAGTGCCAGAATTTTAGGAACTTCAGAGATCGTGT ATTGAGATTTCTTAAATAATGCTTCAGATATTATTGCTTTATTGCTTTTTTGTATTGGTTAAAACTGTACATTTAAAATTGCTATGTTAC TATTTTCTACAATTAATAGTTTGTCTATTTTAAAATAAATTAGTTGTTAAGAGTCTTAATGGTCTGATGTTGTGTTCTTTGTATTAAGTA >81514_81514_9_SH3PXD2A-RB1_SH3PXD2A_chr10_105371338_ENST00000538130_RB1_chr13_49039134_ENST00000267163_length(amino acids)=475AA_BP=284 MPFLSGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEVSK RRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKK NLAGPVEIIGNIMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLAQGSPAVARIAPQRAQISSP NLRTRPPPRRESSLTFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPY KISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQKLAE -------------------------------------------------------------- >81514_81514_10_SH3PXD2A-RB1_SH3PXD2A_chr10_105371338_ENST00000540321_RB1_chr13_49039134_ENST00000267163_length(transcript)=3411nt_BP=920nt AGACATTACACATGAACGGGTCGTTCCTGCTCCGGCTCCTGTTTCCTGTAGCGTCCATCCTGCCAGAGACTGTACTGCTTAGGGGTGCCG ACGCCACCGCCGAGCCCATGATCCTGGAACAGTACGTGGTGGTGTCCAACTATAAGAAGCAGGAGAACTCGGAGCTGAGCCTCCAGGCCG GGGAGGTGGTGGATGTCATCGAGAAGAACGAGAGCGGCTGGTGGTTCGTGAGCACTTCTGAGGAGCAGGGCTGGGTCCCTGCCACCTACC TGGAGGCCCAGAATGGTACTCGGGATGACTCCGACATCAACACCTCTAAGACTGGAGAAGTGTCCAAGAGACGCAAGGCCCATCTGCGGC GCCTGGATCGCCGGTGGACCCTGGGCGGGATGGTCAACAGGCAGCACAGCCGAGAGGAGAAGTATGTCACCGTGCAGCCTTACACCAGCC AAAGCAAGGACGAGATTGGCTTTGAGAAGGGCGTCACAGTGGAGGTGATCCGGAAGAATCTGGAAGGCTGGTGGTATATCAGATACCTGG GCAAAGAGGGCTGGGCGCCAGCATCCTACCTGAAGAAGGCCAAGGATGACCTGCCAACCCGGAAGAAGAACCTGGCCGGCCCAGTGGAGA TCATTGGGAACATCATGGAGATCAGCAACCTGCTGAACAAGAAGGCGTCTGGGGACAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATG AGGCCCCCATTGCCAAGAAGGAGATCAGCCTGCCCATCCTCTGCAATGCCTCCAATGGCAGTGCCGTGGGCGTTCCTGACAGGACTGTCT CCAGGCTGGCCCAGGGCTCTCCAGCTGTGGCCAGGATTGCCCCTCAGCGGGCCCAGATCAGCTCCCCGAACCTACGGACAAGACCTCCAC CACGCAGAGAATCCAGCCTGACATTCAAACGTGTTTTGATCAAAGAAGAGGAGTATGATTCTATTATAGTATTCTATAACTCGGTCTTCA TGCAGAGACTGAAAACAAATATTTTGCAGTATGCTTCCACCAGGCCCCCTACCTTGTCACCAATACCTCACATTCCTCGAAGCCCTTACA AGTTTCCTAGTTCACCCTTACGGATTCCTGGAGGGAACATCTATATTTCACCCCTGAAGAGTCCATATAAAATTTCAGAAGGTCTGCCAA CACCAACAAAAATGACTCCAAGATCAAGAATCTTAGTATCAATTGGTGAATCATTCGGGACTTCTGAGAAGTTCCAGAAAATAAATCAGA TGGTATGTAACAGCGACCGTGTGCTCAAAAGAAGTGCTGAAGGAAGCAACCCTCCTAAACCACTGAAAAAACTACGCTTTGATATTGAAG GATCAGATGAAGCAGATGGAAGTAAACATCTCCCAGGAGAGTCCAAATTTCAGCAGAAACTGGCAGAAATGACTTCTACTCGAACACGAA TGCAAAAGCAGAAAATGAATGATAGCATGGATACCTCAAACAAGGAAGAGAAATGAGGATCTCAGGACCTTGGTGGACACTGTGTACACC TCTGGATTCATTGTCTCTCACAGATGTGACTGTATAACTTTCCCAGGTTCTGTTTATGGCCACATTTAATATCTTCAGCTCTTTTTGTGG ATATAAAATGTGCAGATGCAATTGTTTGGGTGATTCCTAAGCCACTTGAAATGTTAGTCATTGTTATTTATACAAGATTGAAAATCTTGT GTAAATCCTGCCATTTAAAAAGTTGTAGCAGATTGTTTCCTCTTCCAAAGTAAAATTGCTGTGCTTTATGGATAGTAAGAATGGCCCTAG AGTGGGAGTCCTGATAACCCAGGCCTGTCTGACTACTTTGCCTTCTTTTGTAGCATATAGGTGATGTTTGCTCTTGTTTTTATTAATTTA TATGTATATTTTTTTAATTTAACATGAACACCCTTAGAAAATGTGTCCTATCTATCTTCCAAATGCAATTTGATTGACTGCCCATTCACC AAAATTATCCTGAACTCTTCTGCAAAAATGGATATTATTAGAAATTAGAAAAAAATTACTAATTTTACACATTAGATTTTATTTTACTAT TGGAATCTGATATACTGTGTGCTTGTTTTATAAAATTTTGCTTTTAATTAAATAAAAGCTGGAAGCAAAGTATAACCATATGATACTATC ATACTACTGAAACAGATTTCATACCTCAGAATGTAAAAGAACTTACTGATTATTTTCTTCATCCAACTTATGTTTTTAAATGAGGATTAT TGATAGTACTCTTGGTTTTTATACCATTCAGATCACTGAATTTATAAAGTACCCATCTAGTACTTGAAAAAGTAAAGTGTTCTGCCAGAT CTTAGGTATAGAGGACCCTAACACAGTATATCCCAAGTGCACTTTCTAATGTTTCTGGGTCCTGAAGAATTAAGATACAAATTAATTTTA CTCCATAAACAGACTGTTAATTATAGGAGCCTTAATTTTTTTTTCATAGAGATTTGTCTAATTGCATCTCAAAATTATTCTGCCCTCCTT AATTTGGGAAGGTTTGTGTTTTCTCTGGAATGGTACATGTCTTCCATGTATCTTTTGAACTGGCAATTGTCTATTTATCTTTTATTTTTT TAAGTCAGTATGGTCTAACACTGGCATGTTCAAAGCCACATTATTTCTAGTCCAAAATTACAAGTAATCAAGGGTCATTATGGGTTAGGC ATTAATGTTTCTATCTGATTTTGTGCAAAAGCTTCAAATTAAAACAGCTGCATTAGAAAAAGAGGCGCTTCTCCCCTCCCCTACACCTAA AGGTGTATTTAAACTATCTTGTGTGATTAACTTATTTAGAGATGCTGTAACTTAAAATAGGGGATATTTAAGGTAGCTTCAGCTAGCTTT TAGGAAAATCACTTTGTCTAACTCAGAATTATTTTTAAAAAGAAATCTGGTCTTGTTAGAAAACAAAATTTTATTTTGTGCTCATTTAAG TTTCAAACTTACTATTTTGACAGTTATTTTGATAACAATGACACTAGAAAACTTGACTCCATTTCATCATTGTTTCTGCATGAATATCAT ACAAATCAGTTAGTTTTTAGGTCAAGGGCTTACTATTTCTGGGTCTTTTGCTACTAAGTTCACATTAGAATTAGTGCCAGAATTTTAGGA ACTTCAGAGATCGTGTATTGAGATTTCTTAAATAATGCTTCAGATATTATTGCTTTATTGCTTTTTTGTATTGGTTAAAACTGTACATTT AAAATTGCTATGTTACTATTTTCTACAATTAATAGTTTGTCTATTTTAAAATAAATTAGTTGTTAAGAGTCTTAATGGTCTGATGTTGTG >81514_81514_10_SH3PXD2A-RB1_SH3PXD2A_chr10_105371338_ENST00000540321_RB1_chr13_49039134_ENST00000267163_length(amino acids)=494AA_BP=303 MNGSFLLRLLFPVASILPETVLLRGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQ NGTRDDSDINTSKTGEVSKRRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEG WAPASYLKKAKDDLPTRKKNLAGPVEIIGNIMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLA QGSPAVARIAPQRAQISSPNLRTRPPPRRESSLTFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPS SPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDE -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SH3PXD2A-RB1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | RB1 | chr10:105371337 | chr13:49039133 | ENST00000267163 | 20 | 27 | 763_928 | 737.0 | 929.0 | LIMD1 | |
| Tgene | RB1 | chr10:105371338 | chr13:49039134 | ENST00000267163 | 20 | 27 | 763_928 | 737.0 | 929.0 | LIMD1 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SH3PXD2A-RB1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SH3PXD2A-RB1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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