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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SHC1-EFNA3 (FusionGDB2 ID:81637)

Fusion Gene Summary for SHC1-EFNA3

check button Fusion gene summary
Fusion gene informationFusion gene name: SHC1-EFNA3
Fusion gene ID: 81637
HgeneTgene
Gene symbol

SHC1

EFNA3

Gene ID

6464

1944

Gene nameSHC adaptor protein 1ephrin A3
SynonymsSHC|SHCAEFL2|EPLG3|Ehk1-L|LERK3
Cytomap

1q21.3

1q21.3

Type of geneprotein-codingprotein-coding
DescriptionSHC-transforming protein 1SH2 domain protein C1SHC (Src homology 2 domain containing) transforming protein 1SHC-transforming protein 3SHC-transforming protein Aephrin-A3EFL-2EHK1 ligandLERK-3eph-related receptor tyrosine kinase ligand 3ligand of eph-related kinase 3
Modification date2020032720200313
UniProtAcc.

P52797

Ensembl transtripts involved in fusion geneENST00000368445, ENST00000368449, 
ENST00000368450, ENST00000368453, 
ENST00000448116, ENST00000606391, 
ENST00000490667, 		ENST00000498667, 
ENST00000368408, ENST00000418360, 
ENST00000505139, ENST00000556931, 
Fusion gene scores* DoF score12 X 13 X 8=12482 X 1 X 2=4
# samples 152
** MAII scorelog2(15/1248*10)=-3.05658352836637
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/4*10)=2.32192809488736
Context

PubMed: SHC1 [Title/Abstract] AND EFNA3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSHC1(154938019)-EFNA3(155057567), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSHC1

GO:0000165

MAPK cascade

14676841

HgeneSHC1

GO:0000187

activation of MAPK activity

14676841

HgeneSHC1

GO:0071363

cellular response to growth factor stimulus

20010870

TgeneEFNA3

GO:0016525

negative regulation of angiogenesis

18417479


check buttonFusion gene breakpoints across SHC1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EFNA3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CR-7390-01ASHC1chr1

154938019

-EFNA3chr1

155057567

+
ChimerDB4HNSCTCGA-CR-7390SHC1chr1

154938019

-EFNA3chr1

155057567

+


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Fusion Gene ORF analysis for SHC1-EFNA3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000368445ENST00000498667SHC1chr1

154938019

-EFNA3chr1

155057567

+
5CDS-intronENST00000368449ENST00000498667SHC1chr1

154938019

-EFNA3chr1

155057567

+
5CDS-intronENST00000368450ENST00000498667SHC1chr1

154938019

-EFNA3chr1

155057567

+
5CDS-intronENST00000368453ENST00000498667SHC1chr1

154938019

-EFNA3chr1

155057567

+
5CDS-intronENST00000448116ENST00000498667SHC1chr1

154938019

-EFNA3chr1

155057567

+
5CDS-intronENST00000606391ENST00000498667SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000368445ENST00000368408SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000368445ENST00000418360SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000368445ENST00000505139SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000368445ENST00000556931SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000368449ENST00000368408SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000368449ENST00000418360SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000368449ENST00000505139SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000368449ENST00000556931SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000448116ENST00000368408SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000448116ENST00000418360SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000448116ENST00000505139SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000448116ENST00000556931SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000606391ENST00000368408SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000606391ENST00000418360SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000606391ENST00000505139SHC1chr1

154938019

-EFNA3chr1

155057567

+
Frame-shiftENST00000606391ENST00000556931SHC1chr1

154938019

-EFNA3chr1

155057567

+
In-frameENST00000368450ENST00000368408SHC1chr1

154938019

-EFNA3chr1

155057567

+
In-frameENST00000368450ENST00000418360SHC1chr1

154938019

-EFNA3chr1

155057567

+
In-frameENST00000368450ENST00000505139SHC1chr1

154938019

-EFNA3chr1

155057567

+
In-frameENST00000368450ENST00000556931SHC1chr1

154938019

-EFNA3chr1

155057567

+
In-frameENST00000368453ENST00000368408SHC1chr1

154938019

-EFNA3chr1

155057567

+
In-frameENST00000368453ENST00000418360SHC1chr1

154938019

-EFNA3chr1

155057567

+
In-frameENST00000368453ENST00000505139SHC1chr1

154938019

-EFNA3chr1

155057567

+
In-frameENST00000368453ENST00000556931SHC1chr1

154938019

-EFNA3chr1

155057567

+
intron-3CDSENST00000490667ENST00000368408SHC1chr1

154938019

-EFNA3chr1

155057567

+
intron-3CDSENST00000490667ENST00000418360SHC1chr1

154938019

-EFNA3chr1

155057567

+
intron-3CDSENST00000490667ENST00000505139SHC1chr1

154938019

-EFNA3chr1

155057567

+
intron-3CDSENST00000490667ENST00000556931SHC1chr1

154938019

-EFNA3chr1

155057567

+
intron-intronENST00000490667ENST00000498667SHC1chr1

154938019

-EFNA3chr1

155057567

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000368450SHC1chr1154938019-ENST00000556931EFNA3chr1155057567+227314251261892588
ENST00000368450SHC1chr1154938019-ENST00000505139EFNA3chr1155057567+227814251261892588
ENST00000368450SHC1chr1154938019-ENST00000368408EFNA3chr1155057567+300914251261892588
ENST00000368450SHC1chr1154938019-ENST00000418360EFNA3chr1155057567+229914251261814562
ENST00000368453SHC1chr1154938019-ENST00000556931EFNA3chr1155057567+227614281261895589
ENST00000368453SHC1chr1154938019-ENST00000505139EFNA3chr1155057567+228114281261895589
ENST00000368453SHC1chr1154938019-ENST00000368408EFNA3chr1155057567+301214281261895589
ENST00000368453SHC1chr1154938019-ENST00000418360EFNA3chr1155057567+230214281261817563

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000368450ENST00000556931SHC1chr1154938019-EFNA3chr1155057567+0.0814276560.9185723
ENST00000368450ENST00000505139SHC1chr1154938019-EFNA3chr1155057567+0.079703090.92029697
ENST00000368450ENST00000368408SHC1chr1154938019-EFNA3chr1155057567+0.0523875650.9476124
ENST00000368450ENST00000418360SHC1chr1154938019-EFNA3chr1155057567+0.078540320.92145973
ENST00000368453ENST00000556931SHC1chr1154938019-EFNA3chr1155057567+0.08821520.9117848
ENST00000368453ENST00000505139SHC1chr1154938019-EFNA3chr1155057567+0.086802880.91319716
ENST00000368453ENST00000368408SHC1chr1154938019-EFNA3chr1155057567+0.0565825780.9434174
ENST00000368453ENST00000418360SHC1chr1154938019-EFNA3chr1155057567+0.08409240.91590756

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Fusion Genomic Features for SHC1-EFNA3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SHC1chr1154938018-EFNA3chr1155057566+3.73E-060.9999963
SHC1chr1154938018-EFNA3chr1155057566+3.73E-060.9999963
SHC1chr1154938018-EFNA3chr1155057566+3.73E-060.9999963
SHC1chr1154938018-EFNA3chr1155057566+3.73E-060.9999963

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SHC1-EFNA3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:154938019/chr1:155057567)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EFNA3

P52797

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSHC1chr1:154938019chr1:155057567ENST00000368445-1112411_474541584.0Compositional biasNote=Pro-rich
HgeneSHC1chr1:154938019chr1:155057567ENST00000448116-1112411_474542585.0Compositional biasNote=Pro-rich
HgeneSHC1chr1:154938019chr1:155057567ENST00000368445-1112156_339541584.0DomainPID
HgeneSHC1chr1:154938019chr1:155057567ENST00000368450-1213156_339431474.0DomainPID
HgeneSHC1chr1:154938019chr1:155057567ENST00000368453-1213156_339432475.0DomainPID
HgeneSHC1chr1:154938019chr1:155057567ENST00000448116-1112156_339542585.0DomainPID
HgeneSHC1chr1:154938019chr1:155057567ENST00000368445-1112340_487541584.0RegionNote=CH1
HgeneSHC1chr1:154938019chr1:155057567ENST00000448116-1112340_487542585.0RegionNote=CH1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSHC1chr1:154938019chr1:155057567ENST00000368450-1213411_474431474.0Compositional biasNote=Pro-rich
HgeneSHC1chr1:154938019chr1:155057567ENST00000368453-1213411_474432475.0Compositional biasNote=Pro-rich
HgeneSHC1chr1:154938019chr1:155057567ENST00000368445-1112488_579541584.0DomainSH2
HgeneSHC1chr1:154938019chr1:155057567ENST00000368450-1213488_579431474.0DomainSH2
HgeneSHC1chr1:154938019chr1:155057567ENST00000368453-1213488_579432475.0DomainSH2
HgeneSHC1chr1:154938019chr1:155057567ENST00000448116-1112488_579542585.0DomainSH2
HgeneSHC1chr1:154938019chr1:155057567ENST00000368450-1213340_487431474.0RegionNote=CH1
HgeneSHC1chr1:154938019chr1:155057567ENST00000368453-1213340_487432475.0RegionNote=CH1
TgeneEFNA3chr1:154938019chr1:155057567ENST000003684080530_16942239.0DomainEphrin RBD


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Fusion Gene Sequence for SHC1-EFNA3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>81637_81637_1_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368450_EFNA3_chr1_155057567_ENST00000368408_length(transcript)=3009nt_BP=1425nt
GAGTGTAATAAAGTTTCTCCAGGGAGGCAGGGCCCGGGGAGAAAGTTGGAGCGGTAACCTAAGCTGGCAGTGGCGTGATCCGGCACCAAA
TCGGCCCGCGGTGCGGTGCGGAGACTCCATGAGGCCCTGGACATGAACAAGCTGAGTGGAGGCGGCGGGCGCAGGACTCGGGTGGAAGGG
GGCCAGCTTGGGGGCGAGGAGTGGACCCGCCACGGGAGCTTTGTCAATAAGCCCACGCGGGGCTGGCTGCATCCCAACGACAAAGTCATG
GGACCCGGGGTTTCCTACTTGGTTCGGTACATGGGTTGTGTGGAGGTCCTCCAGTCAATGCGTGCCCTGGACTTCAACACCCGGACTCAG
GTCACCAGGGAGGCCATCAGTCTGGTGTGTGAGGCTGTGCCGGGTGCTAAGGGGGCGACAAGGAGGAGAAAGCCCTGTAGCCGCCCGCTC
AGCTCTATCCTGGGGAGGAGTAACCTGAAATTTGCTGGAATGCCAATCACTCTCACCGTCTCCACCAGCAGCCTCAACCTCATGGCCGCA
GACTGCAAACAGATCATCGCCAACCACCACATGCAATCTATCTCATTTGCATCCGGCGGGGATCCGGACACAGCCGAGTATGTCGCCTAT
GTTGCCAAAGACCCTGTGAATCAGAGAGCCTGCCACATTCTGGAGTGTCCCGAAGGGCTTGCCCAGGATGTCATCAGCACCATTGGCCAG
GCCTTCGAGTTGCGCTTCAAACAATACCTCAGGAACCCACCCAAACTGGTCACCCCTCATGACAGGATGGCTGGCTTTGATGGCTCAGCA
TGGGATGAGGAGGAGGAAGAGCCACCTGACCATCAGTACTATAATGACTTCCCGGGGAAGGAACCCCCCTTGGGGGGGGTGGTAGACATG
AGGCTTCGGGAAGGAGCCGCTCCAGGGGCTGCTCGACCCACTGCACCCAATGCCCAGACCCCCAGCCACTTGGGAGCTACATTGCCTGTA
GGACAGCCTGTTGGGGGAGATCCAGAAGTCCGCAAACAGATGCCACCTCCACCACCCTGTCCAGGCAGAGAGCTTTTTGATGATCCCTCC
TATGTCAACGTCCAGAACCTAGACAAGGCCCGGCAAGCAGTGGGTGGTGCTGGGCCCCCCAATCCTGCTATCAATGGCAGTGCACCCCGG
GACCTGTTTGACATGAAGCCCTTCGAAGATGCTCTTCGCGTGCCTCCACCTCCCCAGTCGGTGTCCATGGCTGAGCAGCTCCGAGGGGAG
CCCTGGTTCCATGGGAAGCTGAGCCGGCGGGAGGCTGAGGCACTGCTGCAGCTCAATGGGGACTTCCTGGTACGGGAGAGCACGACCACA
CCTGGCCAGTATGTGCTCACTGGCTTGCAGAGTGGGCAGCCTAAGCATTTGCTACTGGTGGACCCTGAGGGTGTGCCTGCGGCGAGAGGG
CTACACCGTGCAGGTGAACGTGAACGACTATCTGGATATTTACTGCCCGCACTACAACAGCTCGGGGGTGGGCCCCGGGGCGGGACCGGG
GCCCGGAGGCGGGGCAGAGCAGTACGTGCTGTACATGGTGAGCCGCAACGGCTACCGCACCTGCAACGCCAGCCAGGGCTTCAAGCGCTG
GGAGTGCAACCGGCCGCACGCCCCGCACAGCCCCATCAAGTTCTCGGAGAAGTTCCAGCGCTACAGCGCCTTCTCTCTGGGCTACGAGTT
CCACGCCGGCCACGAGTACTACTACATCTCCACGCCCACTCACAACCTGCACTGGAAGTGTCTGAGGATGAAGGTGTTCGTCTGCTGCGC
CTCCACATCGCACTCCGGGGAGAAGCCGGTCCCCACTCTCCCCCAGTTCACCATGGGCCCCAATGTGAAGATCAACGTGCTGGAAGACTT
TGAGGGAGAGAACCCTCAGGTGCCCAAGCTTGAGAAGAGCATCAGCGGGACCAGCCCCAAACGGGAACACCTGCCCCTGGCCGTGGGCAT
CGCCTTCTTCCTCATGACGTTCTTGGCCTCCTAGCTCTGCCCCCTCCCCTGGGGGGGGAGAGATGGGGCGGGGCTTGGAAGGAGCAGGGA
GCCTTTGGCCTCTCCAAGGGAAGCCTAGTGGGCCTAGACCCCTCCTCCCATGGCTAGAAGTGGGGCCTGCACCATACATCTGTGTCCGCC
CCCTCTACCCCTTCCCCCCACGTAGGGCACTGTAGTGGACCAAGCACGGGGACAGCCATGGGTCCCGGGCGGCCTTGTGGCTCTGGTAAT
GTTTGGTACCAAACTTGGGGGCCAAAAAGGGCAGTGCTCAGGACTCCCTGGCCCCTGGTACCTTTCCCTGACTCCTGGTGCCCTCTCCCT
TTGTCCCCCCAGAGAGACATATGCCCCCAGAGAGAGCAAATCGAAGCGTGGGAGGCACCCCCATTGCTCTCCTCCAGGGGCAGAACATGG
GGAGGGGACTAGATGGGCAAGGGGCAGCACTGCCTGCTGCTTCCTTCCCCTGTTTACAGCAATAAGCACGTCCTCCTCCCCCACTCCCAC
TTCCAGGATTGTGGTTTGGATTGAAACCAAGTTTACAAGTAGACACCCCTGGGGGGGCGGGCAGTGGACAAGGATGGCAAGGGGTGGGCA
TTGGGGTGCCAGGCAGGCATGTACAGACTCTATATCTCTATATATAATGTACAGACAGACAGAGTCCCTTCCCTCTTTAACCCCCTGACC
TTTCTTGACTTCCCCTTCAGCTTCAGACCCCTTCCCCACCAGGCTAGGCCCCCCACACCTGGGGGACCCCCTGGCCCCTCTTTTGTCTTC
TGTGAAGACAGGACCTATGCAACGCACAGACACTTTTGGAGACCGTAAAACAACAACGCCCCCTCCCTTCCAGCCCTGAGCCGGGAACCA
TCTCCCAGGACCTTGCCCTGCTCACCCTATGTGGTCCCACCTATCCTCCTGGGCCTTTTTCAAGTGCTTTGGCTGTGACTTTCATACTCT

>81637_81637_1_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368450_EFNA3_chr1_155057567_ENST00000368408_length(amino acids)=588AA_BP=433
MDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEA
VPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACH
ILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAAR
PTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDAL
RVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVPAARGLHRAGERERLSG
YLLPALQQLGGGPRGGTGARRRGRAVRAVHGEPQRLPHLQRQPGLQALGVQPAARPAQPHQVLGEVPALQRLLSGLRVPRRPRVLLHLHA

--------------------------------------------------------------
>81637_81637_2_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368450_EFNA3_chr1_155057567_ENST00000418360_length(transcript)=2299nt_BP=1425nt
GAGTGTAATAAAGTTTCTCCAGGGAGGCAGGGCCCGGGGAGAAAGTTGGAGCGGTAACCTAAGCTGGCAGTGGCGTGATCCGGCACCAAA
TCGGCCCGCGGTGCGGTGCGGAGACTCCATGAGGCCCTGGACATGAACAAGCTGAGTGGAGGCGGCGGGCGCAGGACTCGGGTGGAAGGG
GGCCAGCTTGGGGGCGAGGAGTGGACCCGCCACGGGAGCTTTGTCAATAAGCCCACGCGGGGCTGGCTGCATCCCAACGACAAAGTCATG
GGACCCGGGGTTTCCTACTTGGTTCGGTACATGGGTTGTGTGGAGGTCCTCCAGTCAATGCGTGCCCTGGACTTCAACACCCGGACTCAG
GTCACCAGGGAGGCCATCAGTCTGGTGTGTGAGGCTGTGCCGGGTGCTAAGGGGGCGACAAGGAGGAGAAAGCCCTGTAGCCGCCCGCTC
AGCTCTATCCTGGGGAGGAGTAACCTGAAATTTGCTGGAATGCCAATCACTCTCACCGTCTCCACCAGCAGCCTCAACCTCATGGCCGCA
GACTGCAAACAGATCATCGCCAACCACCACATGCAATCTATCTCATTTGCATCCGGCGGGGATCCGGACACAGCCGAGTATGTCGCCTAT
GTTGCCAAAGACCCTGTGAATCAGAGAGCCTGCCACATTCTGGAGTGTCCCGAAGGGCTTGCCCAGGATGTCATCAGCACCATTGGCCAG
GCCTTCGAGTTGCGCTTCAAACAATACCTCAGGAACCCACCCAAACTGGTCACCCCTCATGACAGGATGGCTGGCTTTGATGGCTCAGCA
TGGGATGAGGAGGAGGAAGAGCCACCTGACCATCAGTACTATAATGACTTCCCGGGGAAGGAACCCCCCTTGGGGGGGGTGGTAGACATG
AGGCTTCGGGAAGGAGCCGCTCCAGGGGCTGCTCGACCCACTGCACCCAATGCCCAGACCCCCAGCCACTTGGGAGCTACATTGCCTGTA
GGACAGCCTGTTGGGGGAGATCCAGAAGTCCGCAAACAGATGCCACCTCCACCACCCTGTCCAGGCAGAGAGCTTTTTGATGATCCCTCC
TATGTCAACGTCCAGAACCTAGACAAGGCCCGGCAAGCAGTGGGTGGTGCTGGGCCCCCCAATCCTGCTATCAATGGCAGTGCACCCCGG
GACCTGTTTGACATGAAGCCCTTCGAAGATGCTCTTCGCGTGCCTCCACCTCCCCAGTCGGTGTCCATGGCTGAGCAGCTCCGAGGGGAG
CCCTGGTTCCATGGGAAGCTGAGCCGGCGGGAGGCTGAGGCACTGCTGCAGCTCAATGGGGACTTCCTGGTACGGGAGAGCACGACCACA
CCTGGCCAGTATGTGCTCACTGGCTTGCAGAGTGGGCAGCCTAAGCATTTGCTACTGGTGGACCCTGAGGGTGTGCCTGCGGCGAGAGGG
CTACACCGTGCAGGTGAACGTGAACGACTATCTGGATATTTACTGCCCGCACTACAACAGCTCGGGGGTGGGCCCCGGGGCGGGACCGGG
GCCCGGAGGCGGGGCAGAGCAGTACGTGCTGTACATGGTGAGCCGCAACGGCTACCGCACCTGCAACGCCAGCCAGGGCTTCAAGCGCTG
GGAGTGCAACCGGCCGCACGCCCCGCACAGCCCCATCAAGTTCTCGGAGAAGTTCCAGCGCTACAGCGCCTTCTCTCTGGGCTACGAGTT
CCACGCCGGCCACGAGTACTACTACATCTCCACGCCCACTCACAACCTGCACTGGAAGTGTCTGAGGATGAAGGTGTTCGTCTGCTGCGC
CTCCAAAGACTTTGAGGGAGAGAACCCTCAGGTGCCCAAGCTTGAGAAGAGCATCAGCGGGACCAGCCCCAAACGGGAACACCTGCCCCT
GGCCGTGGGCATCGCCTTCTTCCTCATGACGTTCTTGGCCTCCTAGCTCTGCCCCCTCCCCTGGGGGGGGAGAGATGGGGCGGGGCTTGG
AAGGAGCAGGGAGCCTTTGGCCTCTCCAAGGGAAGCCTAGTGGGCCTAGACCCCTCCTCCCATGGCTAGAAGTGGGGCCTGCACCATACA
TCTGTGTCCGCCCCCTCTACCCCTTCCCCCCACGTAGGGCACTGTAGTGGACCAAGCACGGGGACAGCCATGGGTCCCGGGCGGCCTTGT
GGCTCTGGTAATGTTTGGTACCAAACTTGGGGGCCAAAAAGGGCAGTGCTCAGGACTCCCTGGCCCCTGGTACCTTTCCCTGACTCCTGG

>81637_81637_2_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368450_EFNA3_chr1_155057567_ENST00000418360_length(amino acids)=562AA_BP=433
MDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEA
VPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACH
ILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAAR
PTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDAL
RVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVPAARGLHRAGERERLSG
YLLPALQQLGGGPRGGTGARRRGRAVRAVHGEPQRLPHLQRQPGLQALGVQPAARPAQPHQVLGEVPALQRLLSGLRVPRRPRVLLHLHA

--------------------------------------------------------------
>81637_81637_3_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368450_EFNA3_chr1_155057567_ENST00000505139_length(transcript)=2278nt_BP=1425nt
GAGTGTAATAAAGTTTCTCCAGGGAGGCAGGGCCCGGGGAGAAAGTTGGAGCGGTAACCTAAGCTGGCAGTGGCGTGATCCGGCACCAAA
TCGGCCCGCGGTGCGGTGCGGAGACTCCATGAGGCCCTGGACATGAACAAGCTGAGTGGAGGCGGCGGGCGCAGGACTCGGGTGGAAGGG
GGCCAGCTTGGGGGCGAGGAGTGGACCCGCCACGGGAGCTTTGTCAATAAGCCCACGCGGGGCTGGCTGCATCCCAACGACAAAGTCATG
GGACCCGGGGTTTCCTACTTGGTTCGGTACATGGGTTGTGTGGAGGTCCTCCAGTCAATGCGTGCCCTGGACTTCAACACCCGGACTCAG
GTCACCAGGGAGGCCATCAGTCTGGTGTGTGAGGCTGTGCCGGGTGCTAAGGGGGCGACAAGGAGGAGAAAGCCCTGTAGCCGCCCGCTC
AGCTCTATCCTGGGGAGGAGTAACCTGAAATTTGCTGGAATGCCAATCACTCTCACCGTCTCCACCAGCAGCCTCAACCTCATGGCCGCA
GACTGCAAACAGATCATCGCCAACCACCACATGCAATCTATCTCATTTGCATCCGGCGGGGATCCGGACACAGCCGAGTATGTCGCCTAT
GTTGCCAAAGACCCTGTGAATCAGAGAGCCTGCCACATTCTGGAGTGTCCCGAAGGGCTTGCCCAGGATGTCATCAGCACCATTGGCCAG
GCCTTCGAGTTGCGCTTCAAACAATACCTCAGGAACCCACCCAAACTGGTCACCCCTCATGACAGGATGGCTGGCTTTGATGGCTCAGCA
TGGGATGAGGAGGAGGAAGAGCCACCTGACCATCAGTACTATAATGACTTCCCGGGGAAGGAACCCCCCTTGGGGGGGGTGGTAGACATG
AGGCTTCGGGAAGGAGCCGCTCCAGGGGCTGCTCGACCCACTGCACCCAATGCCCAGACCCCCAGCCACTTGGGAGCTACATTGCCTGTA
GGACAGCCTGTTGGGGGAGATCCAGAAGTCCGCAAACAGATGCCACCTCCACCACCCTGTCCAGGCAGAGAGCTTTTTGATGATCCCTCC
TATGTCAACGTCCAGAACCTAGACAAGGCCCGGCAAGCAGTGGGTGGTGCTGGGCCCCCCAATCCTGCTATCAATGGCAGTGCACCCCGG
GACCTGTTTGACATGAAGCCCTTCGAAGATGCTCTTCGCGTGCCTCCACCTCCCCAGTCGGTGTCCATGGCTGAGCAGCTCCGAGGGGAG
CCCTGGTTCCATGGGAAGCTGAGCCGGCGGGAGGCTGAGGCACTGCTGCAGCTCAATGGGGACTTCCTGGTACGGGAGAGCACGACCACA
CCTGGCCAGTATGTGCTCACTGGCTTGCAGAGTGGGCAGCCTAAGCATTTGCTACTGGTGGACCCTGAGGGTGTGCCTGCGGCGAGAGGG
CTACACCGTGCAGGTGAACGTGAACGACTATCTGGATATTTACTGCCCGCACTACAACAGCTCGGGGGTGGGCCCCGGGGCGGGACCGGG
GCCCGGAGGCGGGGCAGAGCAGTACGTGCTGTACATGGTGAGCCGCAACGGCTACCGCACCTGCAACGCCAGCCAGGGCTTCAAGCGCTG
GGAGTGCAACCGGCCGCACGCCCCGCACAGCCCCATCAAGTTCTCGGAGAAGTTCCAGCGCTACAGCGCCTTCTCTCTGGGCTACGAGTT
CCACGCCGGCCACGAGTACTACTACATCTCCACGCCCACTCACAACCTGCACTGGAAGTGTCTGAGGATGAAGGTGTTCGTCTGCTGCGC
CTCCACATCGCACTCCGGGGAGAAGCCGGTCCCCACTCTCCCCCAGTTCACCATGGGCCCCAATGTGAAGATCAACGTGCTGGAAGACTT
TGAGGGAGAGAACCCTCAGGTGCCCAAGCTTGAGAAGAGCATCAGCGGGACCAGCCCCAAACGGGAACACCTGCCCCTGGCCGTGGGCAT
CGCCTTCTTCCTCATGACGTTCTTGGCCTCCTAGCTCTGCCCCCTCCCCTGGGGGGGGAGAGATGGGGCGGGGCTTGGAAGGAGCAGGGA
GCCTTTGGCCTCTCCAAGGGAAGCCTAGTGGGCCTAGACCCCTCCTCCCATGGCTAGAAGTGGGGCCTGCACCATACATCTGTGTCCGCC
CCCTCTACCCCTTCCCCCCACGTAGGGCACTGTAGTGGACCAAGCACGGGGACAGCCATGGGTCCCGGGCGGCCTTGTGGCTCTGGTAAT

>81637_81637_3_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368450_EFNA3_chr1_155057567_ENST00000505139_length(amino acids)=588AA_BP=433
MDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEA
VPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACH
ILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAAR
PTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDAL
RVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVPAARGLHRAGERERLSG
YLLPALQQLGGGPRGGTGARRRGRAVRAVHGEPQRLPHLQRQPGLQALGVQPAARPAQPHQVLGEVPALQRLLSGLRVPRRPRVLLHLHA

--------------------------------------------------------------
>81637_81637_4_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368450_EFNA3_chr1_155057567_ENST00000556931_length(transcript)=2273nt_BP=1425nt
GAGTGTAATAAAGTTTCTCCAGGGAGGCAGGGCCCGGGGAGAAAGTTGGAGCGGTAACCTAAGCTGGCAGTGGCGTGATCCGGCACCAAA
TCGGCCCGCGGTGCGGTGCGGAGACTCCATGAGGCCCTGGACATGAACAAGCTGAGTGGAGGCGGCGGGCGCAGGACTCGGGTGGAAGGG
GGCCAGCTTGGGGGCGAGGAGTGGACCCGCCACGGGAGCTTTGTCAATAAGCCCACGCGGGGCTGGCTGCATCCCAACGACAAAGTCATG
GGACCCGGGGTTTCCTACTTGGTTCGGTACATGGGTTGTGTGGAGGTCCTCCAGTCAATGCGTGCCCTGGACTTCAACACCCGGACTCAG
GTCACCAGGGAGGCCATCAGTCTGGTGTGTGAGGCTGTGCCGGGTGCTAAGGGGGCGACAAGGAGGAGAAAGCCCTGTAGCCGCCCGCTC
AGCTCTATCCTGGGGAGGAGTAACCTGAAATTTGCTGGAATGCCAATCACTCTCACCGTCTCCACCAGCAGCCTCAACCTCATGGCCGCA
GACTGCAAACAGATCATCGCCAACCACCACATGCAATCTATCTCATTTGCATCCGGCGGGGATCCGGACACAGCCGAGTATGTCGCCTAT
GTTGCCAAAGACCCTGTGAATCAGAGAGCCTGCCACATTCTGGAGTGTCCCGAAGGGCTTGCCCAGGATGTCATCAGCACCATTGGCCAG
GCCTTCGAGTTGCGCTTCAAACAATACCTCAGGAACCCACCCAAACTGGTCACCCCTCATGACAGGATGGCTGGCTTTGATGGCTCAGCA
TGGGATGAGGAGGAGGAAGAGCCACCTGACCATCAGTACTATAATGACTTCCCGGGGAAGGAACCCCCCTTGGGGGGGGTGGTAGACATG
AGGCTTCGGGAAGGAGCCGCTCCAGGGGCTGCTCGACCCACTGCACCCAATGCCCAGACCCCCAGCCACTTGGGAGCTACATTGCCTGTA
GGACAGCCTGTTGGGGGAGATCCAGAAGTCCGCAAACAGATGCCACCTCCACCACCCTGTCCAGGCAGAGAGCTTTTTGATGATCCCTCC
TATGTCAACGTCCAGAACCTAGACAAGGCCCGGCAAGCAGTGGGTGGTGCTGGGCCCCCCAATCCTGCTATCAATGGCAGTGCACCCCGG
GACCTGTTTGACATGAAGCCCTTCGAAGATGCTCTTCGCGTGCCTCCACCTCCCCAGTCGGTGTCCATGGCTGAGCAGCTCCGAGGGGAG
CCCTGGTTCCATGGGAAGCTGAGCCGGCGGGAGGCTGAGGCACTGCTGCAGCTCAATGGGGACTTCCTGGTACGGGAGAGCACGACCACA
CCTGGCCAGTATGTGCTCACTGGCTTGCAGAGTGGGCAGCCTAAGCATTTGCTACTGGTGGACCCTGAGGGTGTGCCTGCGGCGAGAGGG
CTACACCGTGCAGGTGAACGTGAACGACTATCTGGATATTTACTGCCCGCACTACAACAGCTCGGGGGTGGGCCCCGGGGCGGGACCGGG
GCCCGGAGGCGGGGCAGAGCAGTACGTGCTGTACATGGTGAGCCGCAACGGCTACCGCACCTGCAACGCCAGCCAGGGCTTCAAGCGCTG
GGAGTGCAACCGGCCGCACGCCCCGCACAGCCCCATCAAGTTCTCGGAGAAGTTCCAGCGCTACAGCGCCTTCTCTCTGGGCTACGAGTT
CCACGCCGGCCACGAGTACTACTACATCTCCACGCCCACTCACAACCTGCACTGGAAGTGTCTGAGGATGAAGGTGTTCGTCTGCTGCGC
CTCCACATCGCACTCCGGGGAGAAGCCGGTCCCCACTCTCCCCCAGTTCACCATGGGCCCCAATGTGAAGATCAACGTGCTGGAAGACTT
TGAGGGAGAGAACCCTCAGGTGCCCAAGCTTGAGAAGAGCATCAGCGGGACCAGCCCCAAACGGGAACACCTGCCCCTGGCCGTGGGCAT
CGCCTTCTTCCTCATGACGTTCTTGGCCTCCTAGCTCTGCCCCCTCCCCTGGGGGGGGAGAGATGGGGCGGGGCTTGGAAGGAGCAGGGA
GCCTTTGGCCTCTCCAAGGGAAGCCTAGTGGGCCTAGACCCCTCCTCCCATGGCTAGAAGTGGGGCCTGCACCATACATCTGTGTCCGCC
CCCTCTACCCCTTCCCCCCACGTAGGGCACTGTAGTGGACCAAGCACGGGGACAGCCATGGGTCCCGGGCGGCCTTGTGGCTCTGGTAAT

>81637_81637_4_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368450_EFNA3_chr1_155057567_ENST00000556931_length(amino acids)=588AA_BP=433
MDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEA
VPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACH
ILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAAR
PTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDAL
RVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVPAARGLHRAGERERLSG
YLLPALQQLGGGPRGGTGARRRGRAVRAVHGEPQRLPHLQRQPGLQALGVQPAARPAQPHQVLGEVPALQRLLSGLRVPRRPRVLLHLHA

--------------------------------------------------------------
>81637_81637_5_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368453_EFNA3_chr1_155057567_ENST00000368408_length(transcript)=3012nt_BP=1428nt
GAGTGTAATAAAGTTTCTCCAGGGAGGCAGGGCCCGGGGAGAAAGTTGGAGCGGTAACCTAAGCTGGCAGTGGCGTGATCCGGCACCAAA
TCGGCCCGCGGTGCGGTGCGGAGACTCCATGAGGCCCTGGACATGAACAAGCTGAGTGGAGGCGGCGGGCGCAGGACTCGGGTGGAAGGG
GGCCAGCTTGGGGGCGAGGAGTGGACCCGCCACGGGAGCTTTGTCAATAAGCCCACGCGGGGCTGGCTGCATCCCAACGACAAAGTCATG
GGACCCGGGGTTTCCTACTTGGTTCGGTACATGGGTTGTGTGGAGGTCCTCCAGTCAATGCGTGCCCTGGACTTCAACACCCGGACTCAG
GTCACCAGGGAGGCCATCAGTCTGGTGTGTGAGGCTGTGCCGGGTGCTAAGGGGGCGACAAGGAGGAGAAAGCCCTGTAGCCGCCCGCTC
AGCTCTATCCTGGGGAGGAGTAACCTGAAATTTGCTGGAATGCCAATCACTCTCACCGTCTCCACCAGCAGCCTCAACCTCATGGCCGCA
GACTGCAAACAGATCATCGCCAACCACCACATGCAATCTATCTCATTTGCATCCGGCGGGGATCCGGACACAGCCGAGTATGTCGCCTAT
GTTGCCAAAGACCCTGTGAATCAGAGAGCCTGCCACATTCTGGAGTGTCCCGAAGGGCTTGCCCAGGATGTCATCAGCACCATTGGCCAG
GCCTTCGAGTTGCGCTTCAAACAATACCTCAGGAACCCACCCAAACTGGTCACCCCTCATGACAGGATGGCTGGCTTTGATGGCTCAGCA
TGGGATGAGGAGGAGGAAGAGCCACCTGACCATCAGTACTATAATGACTTCCCGGGGAAGGAACCCCCCTTGGGGGGGGTGGTAGACATG
AGGCTTCGGGAAGGAGCCGCTCCAGGGGCTGCTCGACCCACTGCACCCAATGCCCAGACCCCCAGCCACTTGGGAGCTACATTGCCTGTA
GGACAGCCTGTTGGGGGAGATCCAGAAGTCCGCAAACAGATGCCACCTCCACCACCCTGTCCAGCAGGCAGAGAGCTTTTTGATGATCCC
TCCTATGTCAACGTCCAGAACCTAGACAAGGCCCGGCAAGCAGTGGGTGGTGCTGGGCCCCCCAATCCTGCTATCAATGGCAGTGCACCC
CGGGACCTGTTTGACATGAAGCCCTTCGAAGATGCTCTTCGCGTGCCTCCACCTCCCCAGTCGGTGTCCATGGCTGAGCAGCTCCGAGGG
GAGCCCTGGTTCCATGGGAAGCTGAGCCGGCGGGAGGCTGAGGCACTGCTGCAGCTCAATGGGGACTTCCTGGTACGGGAGAGCACGACC
ACACCTGGCCAGTATGTGCTCACTGGCTTGCAGAGTGGGCAGCCTAAGCATTTGCTACTGGTGGACCCTGAGGGTGTGCCTGCGGCGAGA
GGGCTACACCGTGCAGGTGAACGTGAACGACTATCTGGATATTTACTGCCCGCACTACAACAGCTCGGGGGTGGGCCCCGGGGCGGGACC
GGGGCCCGGAGGCGGGGCAGAGCAGTACGTGCTGTACATGGTGAGCCGCAACGGCTACCGCACCTGCAACGCCAGCCAGGGCTTCAAGCG
CTGGGAGTGCAACCGGCCGCACGCCCCGCACAGCCCCATCAAGTTCTCGGAGAAGTTCCAGCGCTACAGCGCCTTCTCTCTGGGCTACGA
GTTCCACGCCGGCCACGAGTACTACTACATCTCCACGCCCACTCACAACCTGCACTGGAAGTGTCTGAGGATGAAGGTGTTCGTCTGCTG
CGCCTCCACATCGCACTCCGGGGAGAAGCCGGTCCCCACTCTCCCCCAGTTCACCATGGGCCCCAATGTGAAGATCAACGTGCTGGAAGA
CTTTGAGGGAGAGAACCCTCAGGTGCCCAAGCTTGAGAAGAGCATCAGCGGGACCAGCCCCAAACGGGAACACCTGCCCCTGGCCGTGGG
CATCGCCTTCTTCCTCATGACGTTCTTGGCCTCCTAGCTCTGCCCCCTCCCCTGGGGGGGGAGAGATGGGGCGGGGCTTGGAAGGAGCAG
GGAGCCTTTGGCCTCTCCAAGGGAAGCCTAGTGGGCCTAGACCCCTCCTCCCATGGCTAGAAGTGGGGCCTGCACCATACATCTGTGTCC
GCCCCCTCTACCCCTTCCCCCCACGTAGGGCACTGTAGTGGACCAAGCACGGGGACAGCCATGGGTCCCGGGCGGCCTTGTGGCTCTGGT
AATGTTTGGTACCAAACTTGGGGGCCAAAAAGGGCAGTGCTCAGGACTCCCTGGCCCCTGGTACCTTTCCCTGACTCCTGGTGCCCTCTC
CCTTTGTCCCCCCAGAGAGACATATGCCCCCAGAGAGAGCAAATCGAAGCGTGGGAGGCACCCCCATTGCTCTCCTCCAGGGGCAGAACA
TGGGGAGGGGACTAGATGGGCAAGGGGCAGCACTGCCTGCTGCTTCCTTCCCCTGTTTACAGCAATAAGCACGTCCTCCTCCCCCACTCC
CACTTCCAGGATTGTGGTTTGGATTGAAACCAAGTTTACAAGTAGACACCCCTGGGGGGGCGGGCAGTGGACAAGGATGGCAAGGGGTGG
GCATTGGGGTGCCAGGCAGGCATGTACAGACTCTATATCTCTATATATAATGTACAGACAGACAGAGTCCCTTCCCTCTTTAACCCCCTG
ACCTTTCTTGACTTCCCCTTCAGCTTCAGACCCCTTCCCCACCAGGCTAGGCCCCCCACACCTGGGGGACCCCCTGGCCCCTCTTTTGTC
TTCTGTGAAGACAGGACCTATGCAACGCACAGACACTTTTGGAGACCGTAAAACAACAACGCCCCCTCCCTTCCAGCCCTGAGCCGGGAA
CCATCTCCCAGGACCTTGCCCTGCTCACCCTATGTGGTCCCACCTATCCTCCTGGGCCTTTTTCAAGTGCTTTGGCTGTGACTTTCATAC

>81637_81637_5_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368453_EFNA3_chr1_155057567_ENST00000368408_length(amino acids)=589AA_BP=434
MDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEA
VPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACH
ILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAAR
PTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDA
LRVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVPAARGLHRAGERERLS
GYLLPALQQLGGGPRGGTGARRRGRAVRAVHGEPQRLPHLQRQPGLQALGVQPAARPAQPHQVLGEVPALQRLLSGLRVPRRPRVLLHLH

--------------------------------------------------------------
>81637_81637_6_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368453_EFNA3_chr1_155057567_ENST00000418360_length(transcript)=2302nt_BP=1428nt
GAGTGTAATAAAGTTTCTCCAGGGAGGCAGGGCCCGGGGAGAAAGTTGGAGCGGTAACCTAAGCTGGCAGTGGCGTGATCCGGCACCAAA
TCGGCCCGCGGTGCGGTGCGGAGACTCCATGAGGCCCTGGACATGAACAAGCTGAGTGGAGGCGGCGGGCGCAGGACTCGGGTGGAAGGG
GGCCAGCTTGGGGGCGAGGAGTGGACCCGCCACGGGAGCTTTGTCAATAAGCCCACGCGGGGCTGGCTGCATCCCAACGACAAAGTCATG
GGACCCGGGGTTTCCTACTTGGTTCGGTACATGGGTTGTGTGGAGGTCCTCCAGTCAATGCGTGCCCTGGACTTCAACACCCGGACTCAG
GTCACCAGGGAGGCCATCAGTCTGGTGTGTGAGGCTGTGCCGGGTGCTAAGGGGGCGACAAGGAGGAGAAAGCCCTGTAGCCGCCCGCTC
AGCTCTATCCTGGGGAGGAGTAACCTGAAATTTGCTGGAATGCCAATCACTCTCACCGTCTCCACCAGCAGCCTCAACCTCATGGCCGCA
GACTGCAAACAGATCATCGCCAACCACCACATGCAATCTATCTCATTTGCATCCGGCGGGGATCCGGACACAGCCGAGTATGTCGCCTAT
GTTGCCAAAGACCCTGTGAATCAGAGAGCCTGCCACATTCTGGAGTGTCCCGAAGGGCTTGCCCAGGATGTCATCAGCACCATTGGCCAG
GCCTTCGAGTTGCGCTTCAAACAATACCTCAGGAACCCACCCAAACTGGTCACCCCTCATGACAGGATGGCTGGCTTTGATGGCTCAGCA
TGGGATGAGGAGGAGGAAGAGCCACCTGACCATCAGTACTATAATGACTTCCCGGGGAAGGAACCCCCCTTGGGGGGGGTGGTAGACATG
AGGCTTCGGGAAGGAGCCGCTCCAGGGGCTGCTCGACCCACTGCACCCAATGCCCAGACCCCCAGCCACTTGGGAGCTACATTGCCTGTA
GGACAGCCTGTTGGGGGAGATCCAGAAGTCCGCAAACAGATGCCACCTCCACCACCCTGTCCAGCAGGCAGAGAGCTTTTTGATGATCCC
TCCTATGTCAACGTCCAGAACCTAGACAAGGCCCGGCAAGCAGTGGGTGGTGCTGGGCCCCCCAATCCTGCTATCAATGGCAGTGCACCC
CGGGACCTGTTTGACATGAAGCCCTTCGAAGATGCTCTTCGCGTGCCTCCACCTCCCCAGTCGGTGTCCATGGCTGAGCAGCTCCGAGGG
GAGCCCTGGTTCCATGGGAAGCTGAGCCGGCGGGAGGCTGAGGCACTGCTGCAGCTCAATGGGGACTTCCTGGTACGGGAGAGCACGACC
ACACCTGGCCAGTATGTGCTCACTGGCTTGCAGAGTGGGCAGCCTAAGCATTTGCTACTGGTGGACCCTGAGGGTGTGCCTGCGGCGAGA
GGGCTACACCGTGCAGGTGAACGTGAACGACTATCTGGATATTTACTGCCCGCACTACAACAGCTCGGGGGTGGGCCCCGGGGCGGGACC
GGGGCCCGGAGGCGGGGCAGAGCAGTACGTGCTGTACATGGTGAGCCGCAACGGCTACCGCACCTGCAACGCCAGCCAGGGCTTCAAGCG
CTGGGAGTGCAACCGGCCGCACGCCCCGCACAGCCCCATCAAGTTCTCGGAGAAGTTCCAGCGCTACAGCGCCTTCTCTCTGGGCTACGA
GTTCCACGCCGGCCACGAGTACTACTACATCTCCACGCCCACTCACAACCTGCACTGGAAGTGTCTGAGGATGAAGGTGTTCGTCTGCTG
CGCCTCCAAAGACTTTGAGGGAGAGAACCCTCAGGTGCCCAAGCTTGAGAAGAGCATCAGCGGGACCAGCCCCAAACGGGAACACCTGCC
CCTGGCCGTGGGCATCGCCTTCTTCCTCATGACGTTCTTGGCCTCCTAGCTCTGCCCCCTCCCCTGGGGGGGGAGAGATGGGGCGGGGCT
TGGAAGGAGCAGGGAGCCTTTGGCCTCTCCAAGGGAAGCCTAGTGGGCCTAGACCCCTCCTCCCATGGCTAGAAGTGGGGCCTGCACCAT
ACATCTGTGTCCGCCCCCTCTACCCCTTCCCCCCACGTAGGGCACTGTAGTGGACCAAGCACGGGGACAGCCATGGGTCCCGGGCGGCCT
TGTGGCTCTGGTAATGTTTGGTACCAAACTTGGGGGCCAAAAAGGGCAGTGCTCAGGACTCCCTGGCCCCTGGTACCTTTCCCTGACTCC

>81637_81637_6_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368453_EFNA3_chr1_155057567_ENST00000418360_length(amino acids)=563AA_BP=434
MDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEA
VPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACH
ILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAAR
PTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDA
LRVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVPAARGLHRAGERERLS
GYLLPALQQLGGGPRGGTGARRRGRAVRAVHGEPQRLPHLQRQPGLQALGVQPAARPAQPHQVLGEVPALQRLLSGLRVPRRPRVLLHLH

--------------------------------------------------------------
>81637_81637_7_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368453_EFNA3_chr1_155057567_ENST00000505139_length(transcript)=2281nt_BP=1428nt
GAGTGTAATAAAGTTTCTCCAGGGAGGCAGGGCCCGGGGAGAAAGTTGGAGCGGTAACCTAAGCTGGCAGTGGCGTGATCCGGCACCAAA
TCGGCCCGCGGTGCGGTGCGGAGACTCCATGAGGCCCTGGACATGAACAAGCTGAGTGGAGGCGGCGGGCGCAGGACTCGGGTGGAAGGG
GGCCAGCTTGGGGGCGAGGAGTGGACCCGCCACGGGAGCTTTGTCAATAAGCCCACGCGGGGCTGGCTGCATCCCAACGACAAAGTCATG
GGACCCGGGGTTTCCTACTTGGTTCGGTACATGGGTTGTGTGGAGGTCCTCCAGTCAATGCGTGCCCTGGACTTCAACACCCGGACTCAG
GTCACCAGGGAGGCCATCAGTCTGGTGTGTGAGGCTGTGCCGGGTGCTAAGGGGGCGACAAGGAGGAGAAAGCCCTGTAGCCGCCCGCTC
AGCTCTATCCTGGGGAGGAGTAACCTGAAATTTGCTGGAATGCCAATCACTCTCACCGTCTCCACCAGCAGCCTCAACCTCATGGCCGCA
GACTGCAAACAGATCATCGCCAACCACCACATGCAATCTATCTCATTTGCATCCGGCGGGGATCCGGACACAGCCGAGTATGTCGCCTAT
GTTGCCAAAGACCCTGTGAATCAGAGAGCCTGCCACATTCTGGAGTGTCCCGAAGGGCTTGCCCAGGATGTCATCAGCACCATTGGCCAG
GCCTTCGAGTTGCGCTTCAAACAATACCTCAGGAACCCACCCAAACTGGTCACCCCTCATGACAGGATGGCTGGCTTTGATGGCTCAGCA
TGGGATGAGGAGGAGGAAGAGCCACCTGACCATCAGTACTATAATGACTTCCCGGGGAAGGAACCCCCCTTGGGGGGGGTGGTAGACATG
AGGCTTCGGGAAGGAGCCGCTCCAGGGGCTGCTCGACCCACTGCACCCAATGCCCAGACCCCCAGCCACTTGGGAGCTACATTGCCTGTA
GGACAGCCTGTTGGGGGAGATCCAGAAGTCCGCAAACAGATGCCACCTCCACCACCCTGTCCAGCAGGCAGAGAGCTTTTTGATGATCCC
TCCTATGTCAACGTCCAGAACCTAGACAAGGCCCGGCAAGCAGTGGGTGGTGCTGGGCCCCCCAATCCTGCTATCAATGGCAGTGCACCC
CGGGACCTGTTTGACATGAAGCCCTTCGAAGATGCTCTTCGCGTGCCTCCACCTCCCCAGTCGGTGTCCATGGCTGAGCAGCTCCGAGGG
GAGCCCTGGTTCCATGGGAAGCTGAGCCGGCGGGAGGCTGAGGCACTGCTGCAGCTCAATGGGGACTTCCTGGTACGGGAGAGCACGACC
ACACCTGGCCAGTATGTGCTCACTGGCTTGCAGAGTGGGCAGCCTAAGCATTTGCTACTGGTGGACCCTGAGGGTGTGCCTGCGGCGAGA
GGGCTACACCGTGCAGGTGAACGTGAACGACTATCTGGATATTTACTGCCCGCACTACAACAGCTCGGGGGTGGGCCCCGGGGCGGGACC
GGGGCCCGGAGGCGGGGCAGAGCAGTACGTGCTGTACATGGTGAGCCGCAACGGCTACCGCACCTGCAACGCCAGCCAGGGCTTCAAGCG
CTGGGAGTGCAACCGGCCGCACGCCCCGCACAGCCCCATCAAGTTCTCGGAGAAGTTCCAGCGCTACAGCGCCTTCTCTCTGGGCTACGA
GTTCCACGCCGGCCACGAGTACTACTACATCTCCACGCCCACTCACAACCTGCACTGGAAGTGTCTGAGGATGAAGGTGTTCGTCTGCTG
CGCCTCCACATCGCACTCCGGGGAGAAGCCGGTCCCCACTCTCCCCCAGTTCACCATGGGCCCCAATGTGAAGATCAACGTGCTGGAAGA
CTTTGAGGGAGAGAACCCTCAGGTGCCCAAGCTTGAGAAGAGCATCAGCGGGACCAGCCCCAAACGGGAACACCTGCCCCTGGCCGTGGG
CATCGCCTTCTTCCTCATGACGTTCTTGGCCTCCTAGCTCTGCCCCCTCCCCTGGGGGGGGAGAGATGGGGCGGGGCTTGGAAGGAGCAG
GGAGCCTTTGGCCTCTCCAAGGGAAGCCTAGTGGGCCTAGACCCCTCCTCCCATGGCTAGAAGTGGGGCCTGCACCATACATCTGTGTCC
GCCCCCTCTACCCCTTCCCCCCACGTAGGGCACTGTAGTGGACCAAGCACGGGGACAGCCATGGGTCCCGGGCGGCCTTGTGGCTCTGGT

>81637_81637_7_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368453_EFNA3_chr1_155057567_ENST00000505139_length(amino acids)=589AA_BP=434
MDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEA
VPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACH
ILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAAR
PTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDA
LRVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVPAARGLHRAGERERLS
GYLLPALQQLGGGPRGGTGARRRGRAVRAVHGEPQRLPHLQRQPGLQALGVQPAARPAQPHQVLGEVPALQRLLSGLRVPRRPRVLLHLH

--------------------------------------------------------------
>81637_81637_8_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368453_EFNA3_chr1_155057567_ENST00000556931_length(transcript)=2276nt_BP=1428nt
GAGTGTAATAAAGTTTCTCCAGGGAGGCAGGGCCCGGGGAGAAAGTTGGAGCGGTAACCTAAGCTGGCAGTGGCGTGATCCGGCACCAAA
TCGGCCCGCGGTGCGGTGCGGAGACTCCATGAGGCCCTGGACATGAACAAGCTGAGTGGAGGCGGCGGGCGCAGGACTCGGGTGGAAGGG
GGCCAGCTTGGGGGCGAGGAGTGGACCCGCCACGGGAGCTTTGTCAATAAGCCCACGCGGGGCTGGCTGCATCCCAACGACAAAGTCATG
GGACCCGGGGTTTCCTACTTGGTTCGGTACATGGGTTGTGTGGAGGTCCTCCAGTCAATGCGTGCCCTGGACTTCAACACCCGGACTCAG
GTCACCAGGGAGGCCATCAGTCTGGTGTGTGAGGCTGTGCCGGGTGCTAAGGGGGCGACAAGGAGGAGAAAGCCCTGTAGCCGCCCGCTC
AGCTCTATCCTGGGGAGGAGTAACCTGAAATTTGCTGGAATGCCAATCACTCTCACCGTCTCCACCAGCAGCCTCAACCTCATGGCCGCA
GACTGCAAACAGATCATCGCCAACCACCACATGCAATCTATCTCATTTGCATCCGGCGGGGATCCGGACACAGCCGAGTATGTCGCCTAT
GTTGCCAAAGACCCTGTGAATCAGAGAGCCTGCCACATTCTGGAGTGTCCCGAAGGGCTTGCCCAGGATGTCATCAGCACCATTGGCCAG
GCCTTCGAGTTGCGCTTCAAACAATACCTCAGGAACCCACCCAAACTGGTCACCCCTCATGACAGGATGGCTGGCTTTGATGGCTCAGCA
TGGGATGAGGAGGAGGAAGAGCCACCTGACCATCAGTACTATAATGACTTCCCGGGGAAGGAACCCCCCTTGGGGGGGGTGGTAGACATG
AGGCTTCGGGAAGGAGCCGCTCCAGGGGCTGCTCGACCCACTGCACCCAATGCCCAGACCCCCAGCCACTTGGGAGCTACATTGCCTGTA
GGACAGCCTGTTGGGGGAGATCCAGAAGTCCGCAAACAGATGCCACCTCCACCACCCTGTCCAGCAGGCAGAGAGCTTTTTGATGATCCC
TCCTATGTCAACGTCCAGAACCTAGACAAGGCCCGGCAAGCAGTGGGTGGTGCTGGGCCCCCCAATCCTGCTATCAATGGCAGTGCACCC
CGGGACCTGTTTGACATGAAGCCCTTCGAAGATGCTCTTCGCGTGCCTCCACCTCCCCAGTCGGTGTCCATGGCTGAGCAGCTCCGAGGG
GAGCCCTGGTTCCATGGGAAGCTGAGCCGGCGGGAGGCTGAGGCACTGCTGCAGCTCAATGGGGACTTCCTGGTACGGGAGAGCACGACC
ACACCTGGCCAGTATGTGCTCACTGGCTTGCAGAGTGGGCAGCCTAAGCATTTGCTACTGGTGGACCCTGAGGGTGTGCCTGCGGCGAGA
GGGCTACACCGTGCAGGTGAACGTGAACGACTATCTGGATATTTACTGCCCGCACTACAACAGCTCGGGGGTGGGCCCCGGGGCGGGACC
GGGGCCCGGAGGCGGGGCAGAGCAGTACGTGCTGTACATGGTGAGCCGCAACGGCTACCGCACCTGCAACGCCAGCCAGGGCTTCAAGCG
CTGGGAGTGCAACCGGCCGCACGCCCCGCACAGCCCCATCAAGTTCTCGGAGAAGTTCCAGCGCTACAGCGCCTTCTCTCTGGGCTACGA
GTTCCACGCCGGCCACGAGTACTACTACATCTCCACGCCCACTCACAACCTGCACTGGAAGTGTCTGAGGATGAAGGTGTTCGTCTGCTG
CGCCTCCACATCGCACTCCGGGGAGAAGCCGGTCCCCACTCTCCCCCAGTTCACCATGGGCCCCAATGTGAAGATCAACGTGCTGGAAGA
CTTTGAGGGAGAGAACCCTCAGGTGCCCAAGCTTGAGAAGAGCATCAGCGGGACCAGCCCCAAACGGGAACACCTGCCCCTGGCCGTGGG
CATCGCCTTCTTCCTCATGACGTTCTTGGCCTCCTAGCTCTGCCCCCTCCCCTGGGGGGGGAGAGATGGGGCGGGGCTTGGAAGGAGCAG
GGAGCCTTTGGCCTCTCCAAGGGAAGCCTAGTGGGCCTAGACCCCTCCTCCCATGGCTAGAAGTGGGGCCTGCACCATACATCTGTGTCC
GCCCCCTCTACCCCTTCCCCCCACGTAGGGCACTGTAGTGGACCAAGCACGGGGACAGCCATGGGTCCCGGGCGGCCTTGTGGCTCTGGT

>81637_81637_8_SHC1-EFNA3_SHC1_chr1_154938019_ENST00000368453_EFNA3_chr1_155057567_ENST00000556931_length(amino acids)=589AA_BP=434
MDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEA
VPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACH
ILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAAR
PTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDA
LRVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVPAARGLHRAGERERLS
GYLLPALQQLGGGPRGGTGARRRGRAVRAVHGEPQRLPHLQRQPGLQALGVQPAARPAQPHQVLGEVPALQRLLSGLRVPRRPRVLLHLH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SHC1-EFNA3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SHC1-EFNA3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SHC1-EFNA3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource