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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SHROOM2-FRMPD4 (FusionGDB2 ID:81760) |
Fusion Gene Summary for SHROOM2-FRMPD4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SHROOM2-FRMPD4 | Fusion gene ID: 81760 | Hgene | Tgene | Gene symbol | SHROOM2 | FRMPD4 | Gene ID | 357 | 9758 |
| Gene name | shroom family member 2 | FERM and PDZ domain containing 4 | |
| Synonyms | APXL|HSAPXL | MRX104|PDZD10|PDZK10 | |
| Cytomap | Xp22.2 | Xp22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein Shroom2APX homolog of Xenopusapical-like protein | FERM and PDZ domain-containing protein 4PDZ domain-containing protein 10PSD-95-interacting FERM and PDZ domain proteinPSD-95-interacting regulator of spine morphogenesisPreso | |
| Modification date | 20200313 | 20200320 | |
| UniProtAcc | . | Q14CM0 | |
| Ensembl transtripts involved in fusion gene | ENST00000380913, ENST00000418909, ENST00000493668, | ENST00000380682, | |
| Fusion gene scores | * DoF score | 9 X 9 X 4=324 | 10 X 10 X 3=300 |
| # samples | 9 | 10 | |
| ** MAII score | log2(9/324*10)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/300*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SHROOM2 [Title/Abstract] AND FRMPD4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SHROOM2(9907406)-FRMPD4(12725588), # samples:1 SHROOM2(9912953)-FRMPD4(12724945), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SHROOM2 | GO:0000902 | cell morphogenesis | 16684770 |
| Fusion gene breakpoints across SHROOM2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across FRMPD4 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BLCA | TCGA-XF-AAMQ-01A | SHROOM2 | chrX | 9907406 | + | FRMPD4 | chrX | 12725588 | + |
| ChimerDB4 | BLCA | TCGA-XF-AAMQ-01A | SHROOM2 | chrX | 9912953 | - | FRMPD4 | chrX | 12724945 | + |
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Fusion Gene ORF analysis for SHROOM2-FRMPD4 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000380913 | ENST00000380682 | SHROOM2 | chrX | 9907406 | + | FRMPD4 | chrX | 12725588 | + |
| In-frame | ENST00000380913 | ENST00000380682 | SHROOM2 | chrX | 9912953 | - | FRMPD4 | chrX | 12724945 | + |
| In-frame | ENST00000418909 | ENST00000380682 | SHROOM2 | chrX | 9907406 | + | FRMPD4 | chrX | 12725588 | + |
| In-frame | ENST00000418909 | ENST00000380682 | SHROOM2 | chrX | 9912953 | - | FRMPD4 | chrX | 12724945 | + |
| intron-3CDS | ENST00000493668 | ENST00000380682 | SHROOM2 | chrX | 9907406 | + | FRMPD4 | chrX | 12725588 | + |
| intron-3CDS | ENST00000493668 | ENST00000380682 | SHROOM2 | chrX | 9912953 | - | FRMPD4 | chrX | 12724945 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000380913 | SHROOM2 | chrX | 9907406 | + | ENST00000380682 | FRMPD4 | chrX | 12725588 | + | 11073 | 4401 | 42 | 7082 | 2346 |
| ENST00000418909 | SHROOM2 | chrX | 9907406 | + | ENST00000380682 | FRMPD4 | chrX | 12725588 | + | 8308 | 1636 | 46 | 4317 | 1423 |
| ENST00000380913 | SHROOM2 | chrX | 9912953 | - | ENST00000380682 | FRMPD4 | chrX | 12724945 | + | 11436 | 4674 | 42 | 7445 | 2467 |
| ENST00000418909 | SHROOM2 | chrX | 9912953 | - | ENST00000380682 | FRMPD4 | chrX | 12724945 | + | 8671 | 1909 | 46 | 4680 | 1544 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000380913 | ENST00000380682 | SHROOM2 | chrX | 9907406 | + | FRMPD4 | chrX | 12725588 | + | 0.001230466 | 0.99876946 |
| ENST00000418909 | ENST00000380682 | SHROOM2 | chrX | 9907406 | + | FRMPD4 | chrX | 12725588 | + | 0.00153626 | 0.99846375 |
| ENST00000380913 | ENST00000380682 | SHROOM2 | chrX | 9912953 | - | FRMPD4 | chrX | 12724945 | + | 0.001329768 | 0.9986702 |
| ENST00000418909 | ENST00000380682 | SHROOM2 | chrX | 9912953 | - | FRMPD4 | chrX | 12724945 | + | 0.00169161 | 0.9983084 |
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Fusion Genomic Features for SHROOM2-FRMPD4 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| SHROOM2 | chrX | 9907406 | + | FRMPD4 | chrX | 12725587 | + | 1.55E-12 | 1 |
| SHROOM2 | chrX | 9907406 | + | FRMPD4 | chrX | 12725587 | + | 1.55E-12 | 1 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SHROOM2-FRMPD4 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:9907406/chrX:12725588) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | FRMPD4 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol 4,5-bisphosphate. {ECO:0000269|PubMed:19118189}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SHROOM2 | chrX:9907406 | chrX:12725588 | ENST00000380913 | + | 8 | 10 | 1065_1068 | 1437 | 1617.0 | Compositional bias | Note=Poly-Pro |
| Hgene | SHROOM2 | chrX:9907406 | chrX:12725588 | ENST00000380913 | + | 8 | 10 | 150_153 | 1437 | 1617.0 | Compositional bias | Note=Poly-Ser |
| Hgene | SHROOM2 | chrX:9907406 | chrX:12725588 | ENST00000380913 | + | 8 | 10 | 314_320 | 1437 | 1617.0 | Compositional bias | Note=Poly-Pro |
| Hgene | SHROOM2 | chrX:9907406 | chrX:12725588 | ENST00000380913 | + | 8 | 10 | 343_346 | 1437 | 1617.0 | Compositional bias | Note=Poly-Ala |
| Hgene | SHROOM2 | chrX:9912953 | chrX:12724945 | ENST00000380913 | - | 9 | 10 | 1065_1068 | 1528 | 1617.0 | Compositional bias | Note=Poly-Pro |
| Hgene | SHROOM2 | chrX:9912953 | chrX:12724945 | ENST00000380913 | - | 9 | 10 | 150_153 | 1528 | 1617.0 | Compositional bias | Note=Poly-Ser |
| Hgene | SHROOM2 | chrX:9912953 | chrX:12724945 | ENST00000380913 | - | 9 | 10 | 314_320 | 1528 | 1617.0 | Compositional bias | Note=Poly-Pro |
| Hgene | SHROOM2 | chrX:9912953 | chrX:12724945 | ENST00000380913 | - | 9 | 10 | 343_346 | 1528 | 1617.0 | Compositional bias | Note=Poly-Ala |
| Hgene | SHROOM2 | chrX:9907406 | chrX:12725588 | ENST00000380913 | + | 8 | 10 | 26_108 | 1437 | 1617.0 | Domain | PDZ |
| Hgene | SHROOM2 | chrX:9907406 | chrX:12725588 | ENST00000380913 | + | 8 | 10 | 684_773 | 1437 | 1617.0 | Domain | ASD1 |
| Hgene | SHROOM2 | chrX:9912953 | chrX:12724945 | ENST00000380913 | - | 9 | 10 | 26_108 | 1528 | 1617.0 | Domain | PDZ |
| Hgene | SHROOM2 | chrX:9912953 | chrX:12724945 | ENST00000380913 | - | 9 | 10 | 684_773 | 1528 | 1617.0 | Domain | ASD1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SHROOM2 | chrX:9907406 | chrX:12725588 | ENST00000380913 | + | 8 | 10 | 1317_1611 | 1437 | 1617.0 | Domain | ASD2 |
| Hgene | SHROOM2 | chrX:9912953 | chrX:12724945 | ENST00000380913 | - | 9 | 10 | 1317_1611 | 1528 | 1617.0 | Domain | ASD2 |
| Tgene | FRMPD4 | chrX:9907406 | chrX:12725588 | ENST00000380682 | 11 | 17 | 204_519 | 429 | 1323.0 | Domain | FERM | |
| Tgene | FRMPD4 | chrX:9907406 | chrX:12725588 | ENST00000380682 | 11 | 17 | 33_66 | 429 | 1323.0 | Domain | WW | |
| Tgene | FRMPD4 | chrX:9907406 | chrX:12725588 | ENST00000380682 | 11 | 17 | 78_155 | 429 | 1323.0 | Domain | PDZ | |
| Tgene | FRMPD4 | chrX:9912953 | chrX:12724945 | ENST00000380682 | 10 | 17 | 204_519 | 399 | 1323.0 | Domain | FERM | |
| Tgene | FRMPD4 | chrX:9912953 | chrX:12724945 | ENST00000380682 | 10 | 17 | 33_66 | 399 | 1323.0 | Domain | WW | |
| Tgene | FRMPD4 | chrX:9912953 | chrX:12724945 | ENST00000380682 | 10 | 17 | 78_155 | 399 | 1323.0 | Domain | PDZ |
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Fusion Gene Sequence for SHROOM2-FRMPD4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >81760_81760_1_SHROOM2-FRMPD4_SHROOM2_chrX_9907406_ENST00000380913_FRMPD4_chrX_12725588_ENST00000380682_length(transcript)=11073nt_BP=4401nt TCTGCGGCGCTCGGAGCCTCCCTTGCGATCCCACGGCCGGGACTGCCCGGAGTGCATGGGCGCGGGCCAGGGACGCTGAGCGGTCGCGCC ATGGAGGGCGCCGAGCCCCGCGCGCGGCCCGAGCGCCTGGCCGAGGCCGAGACGCGGGCGGCGGACGGCGGGCGCCTGGTGGAGGTGCAG CTGAGCGGCGGCGCCCCGTGGGGCTTCACCCTGAAGGGCGGCCGCGAGCACGGCGAGCCGCTGGTCATCACCAAGATTGAAGAGGGCAGT AAAGCCGCGGCGGTCGACAAGTTACTGGCTGGAGATGAGATCGTCGGCATCAATGACATTGGTCTCTCAGGGTTTAGACAGGAAGCGATT TGCCTGGTGAAGGGGTCCCATAAGACCCTGAAGCTGGTCGTCAAAAGGAGGAGCGAGCTGGGCTGGAGGCCTCACTCCTGGCATGCCACC AAGTTCTCTGACAGCCACCCCGAGCTAGCGGCCTCCCCATTCACCTCCACCAGCGGCTGTCCTTCCTGGTCCGGCCGACACCACGCGAGT TCTTCCTCCCACGACCTGTCCAGTTCCTGGGAGCAGACGAACCTACAGCGCACCTTAGATCACTTCAGCTCCTTGGGGAGCGTTGACAGC CTGGACCACCCCTCCAGTCGCCTCTCGGTGGCCAAGTCCAACAGCAGCATCGACCACCTGGGCAGCCACAGCAAGCGCGACTCGGCCTAC GGCTCCTTCTCCACCAGCTCTAGCACTCCTGACCACACCTTGTCCAAAGCCGACACGTCCTCCGCAGAGAACATCCTCTACACTGTGGGC CTCTGGGAGGCTCCCAGGCAGGGTGGCCGGCAGGCCCAGGCCGCAGGCGACCCTCAGGGCTCGGAGGAGAAGCTCAGTTGTTTCCCGCCC AGGGTCCCCGGTGACAGCGGCAAAGGCCCCAGGCCAGAGTACAATGCCGAGCCCAAGCTGGCTGCCCCTGGGAGGTCCAATTTTGGGCCA GTCTGGTATGTTCCCGATAAGAAGAAAGCACCATCATCCCCACCTCCTCCCCCTCCCCCTCTCCGCAGTGACAGCTTTGCTGCCACCAAG AGCCACGAGAAGGCCCAGGGCCCTGTGTTCTCAGAGGCGGCTGCGGCACAGCACTTTACGGCCCTGGCCCAGGCTCAGCCTCGTGGTGAC CGGAGACCAGAGCTCACCGATCGGCCTTGGAGGTCAGCACACCCGGGGAGCCTCGGGAAGGGATCGGGAGGCCCGGGCTGCCCACAGGAG GCCCACGCAGACGGCAGCTGGCCGCCCTCCAAGGATGGAGCTTCCAGTAGGCTGCAGGCCTCTCTGTCCAGCTCAGATGTGCGCTTCCCT CAGTCTCCTCATAGCGGCCGACACCCTCCCCTATACAGCGACCACAGCCCCCTCTGTGCTGACAGCCTTGGGCAGGAGCCAGGGGCTGCC AGCTTCCAGAACGACAGCCCTCCTCAGGTGAGGGGGCTCAGCAGCTGTGACCAGAAGCTGGGGAGCGGCTGGCAGGGTCCCCGGCCCTGT GTGCAGGGAGACCTGCAAGCAGCACAGCTCTGGGCGGGATGCTGGCCTTCTGACACAGCCCTTGGAGCCCTCGAGAGTCTTCCCCCACCC ACGGTGGGCCAGAGCCCACGCCATCACCTACCTCAGCCTGAGGGTCCTCCGGATGCCCGCGAGACAGGACGGTGTTACCCGCTGGACAAA GGGGCCGAGGGCTGCTCCGCGGGAGCCCAGGAGCCTCCCAGGGCCAGCCGTGCAGAAAAAGCCAGCCAGAGGCTGGCAGCCAGCATCACG TGGGCAGATGGGGAGAGCAGCAGGATCTGCCCGCAGGAGACGCCCCTGTTGCACTCCCTGACCCAGGAGGGGAAGCGCCGGCCTGAGAGC AGTCCAGAGGACAGCGCCACCAGACCGCCACCGTTCGACGCCCACGTGGGCAAGCCCACCCGAAGAAGCGACCGCTTTGCCACCACCCTG CGGAATGAGATCCAGATGCATAGAGCCAAGCTGCAGAAGAGCCGGAGCACAGTGGCTCTGACTGCAGCAGGGGAGGCGGAGGATGGCACC GGCCGCTGGAGGGCCGGGTTGGGAGGTGGCACCCAGGAAGGACCCCTCGCTGGCACCTATAAAGACCACCTGAAAGAGGCCCAAGCCCGG GTCCTGAGGGCCACGTCCTTCAAGCGCCGCGACTTGGACCCCAACCCAGGAGACCTATACCCGGAGTCACTGGAACACCGGATGGGGGAT CCAGACACTGTCCCCCACTTCTGGGAGGCAGGCCTGGCCCAGCCACCCTCATCTACAAGTGGCGGGCCCCACCCGCCCCGCATCGGAGGC CGGAGACGGTTCACAGCTGAGCAGAAATTGAAGTCCTACTCGGAACCTGAGAAGATGAACGAGGTGGGCCTCACGAGGGGCTACAGTCCT CACCAGCACCCCAGGACATCTGAGGATACTGTGGGCACGTTTGCTGACAGGTGGAAGTTTTTTGAGGAAACGAGCAAACCTGTTCCCCAG AGGCCTGCCCAGAAGCAAGCTCTTCACGGAATCCCGAGAGACAAGCCAGAGAGGCCGCGGACAGCGGGCCGCACATGTGAGGGCACGGAG CCCTGGTCGCGCACCACCTCCCTTGGGGACAGCCTCAACGCTCACAGCGCAGCGGAGAAGGCAGGGACTTCAGACCTGCCGCGGAGGCTC GGCACCTTTGCAGAGTATCAGGCCTCTTGGAAGGAACAGAGGAAACCTCTGGAGGCCAGGAGCTCTGGGCGCTGCCACTCAGCGGATGAC ATCCTGGATGTGAGCCTGGACCCACAGGAGAGGCCGCAGCACGTTCATGGGAGGTCCCGGTCTTCACCGTCCACAGACCACTACAAGCAG GAAGCTTCTGTCGAACTGCGAAGGCAGGCAGGGGACCCCGGCGAGCCCAGAGAAGAGCTTCCCTCCGCAGTCCGGGCCGAGGAGGGACAG TCCACGCCGAGACAAGCAGATGCCCAGTGTCGGGAAGGCAGCCCAGGATCACAGCAGCACCCACCGAGTCAGAAGGCACCGAACCCACCC ACATTCTCTGAACTATCTCACTGCCGGGGAGCCCCAGAGCTGCCCCGGGAGGGCCGGGGCCGAGCGGGAACCCTACCTCGAGATTATAGA TACTCGGAGGAGAGCACCCCAGCAGACTTGGGACCCCGAGCCCAGAGCCCTGGCTCACCCCTGCATGCTCGAGGACAAGACTCGTGGCCA GTGAGCTCAGCCCTGCTCTCCAAGAGGCCAGCCCCACAGAGGCCACCGCCACCCAAGCGCGAGCCCAGGAGATACAGGGCCACAGACGGC GCACCTGCTGACGCCCCCGTGGGCGTCCTCGGCAGGCCCTTCCCAACGCCATCCCCTGCGTCCCTGGATGTGTATGTGGCCCGCCTGTCC CTCTCCCACAGCCCCTCTGTGTTCAGCAGTGCCCAGCCCCAGGACACCCCGAAGGCCACTGTCTGTGAGCGTGGAAGCCAGCATGTGAGC GGGGACGCATCACGTCCTCTGCCAGAAGCACTGCTCCCTCCCAAGCAGCAGCACCTGCGCCTGCAGACGGCCACCATGGAGACCTCGCGC TCCCCCTCGCCCCAGTTCGCCCCCCAGAAACTGACGGACAAACCTCCCCTGCTCATCCAGGATGAGGATTCAACCAGAATTGAGCGGGTG ATGGACAACAACACCACGGTGAAGATGGTGCCCATCAAGATCGTGCACTCGGAGAGCCAGCCAGAGAAGGAGAGCCGCCAGAGCCTGGCA TGCCCCGCCGAGCCACCTGCCCTGCCCCACGGGCTGGAGAAAGACCAGATCAAGACGCTGAGCACATCTGAGCAGTTCTACTCGCGCTTC TGTCTGTACACGCGGCAGGGTGCTGAGCCCGAGGCCCCACATAGGGCCCAGCCGGCTGAGCCCCAGCCCCTGGGCACCCAGGTGCCCCCC GAGAAAGACCGCTGCACCTCCCCTCCAGGGCTCAGCTACATGAAGGCCAAAGAGAAGACTGTGGAAGACCTGAAGTCGGAGGAGCTGGCC AGGGAGATCGTGGGGAAGGATAAGTCCCTGGCCGACATCCTGGATCCCAGTGTGAAGATCAAAACCACTATGGACTTGATGGAAGGCATC TTCCCCAAAGACGAGCACCTCCTGGAAGAAGCCCAGCAACGGAGGAAGCTGCTCCCCAAAATCCCCTCTCCTAGAAGCACAGAGGAGAGG AAAGAGGAGCCCAGCGTGCCTGCGGCCGTGTCCCTGGCCACCAATTCTACCTACTACAGCACGTCGGCCCCCAAGGCGGAGCTGCTGATC AAGATGAAGGACCTGCAGGAGCAGCAGGAGCACGAAGAGGATTCGGGAAGCGACTTGGACCACGACCTGTCGGTGAAGAAGCAGGCAGAA AAGCGCTCGGAAGTGACTCTCCTGGTTGGGCCCCGGTATGGCATAAGCCATGTCATCAACACCAAAACCAATCTGGTGGCTCTTTTAGCC GACTTTAGCCACGTCAACAGGATCGAAATGTTTTCCGAGGAGGAGAGCTTGGTGCGGGTAGAACTCCACGTGCTAGATGTGAAGCCTATC ACGCTTCTGATGGAATCCTCAGATGCCATGAACCTGGCCTGCTTGACGGCTGGATACTACCGGCTGCTTGTTGATTCCAGGAGGTCGATA TTTAACATGGCCAACAAGAAAAACACAGCGACCCAGGAAACAGGACCTGAAAACAAGGGGAAGCATAACCTCCTTGGCCCAGATTGGAAC TGTATACCCCAAATGACCACCTTTATTGGCGAAGGGGAACAAGAAGCCCAGATAACATACATAGATTCAAAGCAGAAGACGGTGGAGATC ACAGACAGCACCATGTGTCCAAAAGAGCACCGGCACTTGTACATAGACAATGCCTATAGTTCAGATGGACTTAACCAGCAGCTGAGCCAG CCCGGGGAGGCCCCCTGTGAGGCAGACTACAGAAGTCTAGCTCAGCGGTCCCTATTGACCCTCTCAGGACCAGAAACTCTGAAGAAAGCA CAGGAATCTCCGAGAGGAGCTAAAGTGTCCTTTATTTTTGGAGACTTCGCCTTGGATGATGGTATTAGTCCCCCAACCCTTGGCTATGAA ACGCTACTAGATGAGGGTCCTGAAATGCTGGAGAAGCAGAGAAATCTCTACATTGGCAGTGCCAATGACATGAAGGGCCTGGATCTCACT CCAGAGGCAGAGGGCATCCAGTTTGTGGAAAATTCTGTTTATGCAAACATAGGCGATGTGAAGAGCTTCCAGGCCGCGGAGGGGATCGAG GAACCCCTCTTGCATGACATCTGTTATGCAGAAAACACTGATGACGCGGAGGACGAGGACGAGGTGAGCTGCGAGGAGGACCTCGTGGTG GGGGAGATGAACCAGCCGGCCATCCTCAACCTGTCTGGGTCAAGCGATGACATCATTGACCTCACATCCCTGCCCCCTCCAGAAGGTGAT GACAATGAGGATGACTTCCTGTTGCGTTCCTTGAACATGGCCATTGCCGCACCCCCACCTGGCTTTAGAGACAGTTCAGATGAAGAGGAC TCTCAGAGCCAGGCAGCTTCCTTCCCCGAGGACAAGGAGAAAGGCAGCAGCCTGCAAAATGATGAGATCCCCGTGTCCCTCATTGACGCT GTGCCCACCAGCGCCGAAGGCAAGTGTGAGAAGGGACTGGATAATGCCGTCGTCTCCACGCTGGGAGCTCTAGAGGCTCTATCCGTGTCA GAAGAACAGCAGACCAGTGACAATTCAGGTGTAGCCATCTTGCGGGCTTATAGTCCTGAGTCTTCGTCAGACTCGGGCAATGAAACTAAC TCTTCTGAAATGACTGAGAGTTCTGAACTGGCCACAGCACAAAAACAGTCAGAAAACCTCTCCCGCATGTTCTTGGCCACTCACGAAGGC TACCACCCCCTTGCAGAAGAGCAGACCGAGTTCCCGGCCTCCAAGACCCCCGCTGGGGGCTTGCCTCCAAAGTCCTCGCACGCCCTGGCT GCTAGGCCAGCAACCGACCTCCCGCCCAAAGTTGTGCCTTCCAAGCAGTTACTTCACTCAGACCACATGGAGATGGAGCCTGAAACTATG GAGACTAAGTCGGTCACTGACTATTTTAGCAAACTGCACATGGGGTCGGTGGCATACTCCTGCACTAGCAAAAGGAAAAGCAAGCTGGCC GATGGTGAGGGGAAGGCACCCCCTAATGGGAACACAACAGGAAAAAAACAGCAGGGGACCAAAACGGCAGAGATGGAGGAGGAGGCCAGT GGTAAATTTGGTACTGTGTCTTCACGAGACAGTCAACACCTGAGCACTTTTAATCTGGAGAGAACTGCCTTTCGCAAGGACAGTCAAAGA TGGTATGTGGCCACTGAAGGTGGGATGGCTGAAAAAAGTGGATTAGAAGCAGCAACAGGGAAAACCTTTCCAAGAGCTTCTGGTCTTGGG GCAAGGGAGGCCGAAGGGAAGGAAGAAGGAGCTCCTGATGGAGAAACCAGTGATGGCTCAGGACTTGGTCAAGGGGACCGCTTCTTAACT GACGTGACCTGTGCATCTTCAGCCAAAGACTTAGATAACCCAGAGGACGCTGACTCGTCCACCTGCGACCATCCTTCCAAGCTTCCTGAG GCTGATGAGAGTGTGGCCCGCCTTTGTGACTACCACTTGGCCAAGCGGATGTCATCACTGCAAAGCGAGGGCCATTTTTCTCTGCAGAGC TCCCAAGGCTCTTCAGTGGATGCAGGCTGTGGCACAGGCAGCAGTGGCAGTGCCTGTGCCACACCCGTGGAGTCGCCGCTCTGCCCCTCC CTGGGGAAGCACTTGATTCCTGACGCTTCTGGGAAAGGCGTGAATTACATTCCTTCAGAGGAGAGAGCCCCTGGGCTTCCCAACCACGGA GCCACCTTTAAGGAACTGCACCCACAGACAGAAGGGATGTGTCCACGGATGACAGTGCCTGCTCTGCACACAGCCATTAACACCGAACCC CTGTTTGGCACATTGAGAGATGGATGCCATCGGCTCCCCAAGATTAAGGAAACCACAGTGTAGCTTTGACAGAGCCTGGGAAGGAGAGAC GAGGAGGCATGCCTTCAGCTTGGTCTCAACATCCTGAAGCTGATCCCATCCTGCTACCATCAAACATTCACTCGGAATCAAAGGTGCCAA TTCCAAATCAAGACCCTAATGATTTCTCCCAAGCAAATCAGGCATACGGAGAGGCTGTGAGCTGGCGGCCACCGGATCTGAGAGGGGGGA GCCTCAGGACACCTCCCAGCCAGAAGGCTCTGAGACATAGCAGCAGTATCCTCTCCGGATCTGTCGATTTGGAGACCTTCCGAGAGAGAA CCAAGGGTGCAGTCAGCTTAAAGTGTCCAGGCATCACAGAAGCACAGGAGGCCAGTTCTGAAAGGCGAGCAGAACTCCCCCTGGGGAGGA AGCTCACCAAAAGTTTTTCCCAAAGCTCAATGCACTTGAGCTCTGAGGGGAGGTTTCACAAAAGGTCCCCAGTGGCTCATAAAGACTCAA AGCTGTATAGGACATTACCCTTGCGGAAGCTGGAGGGCAGCAATTGGAGATGCCGGGGACCCTTCAGCTATTGCTTCCTGAACCGAGGGC AGGATGAAGATGGTGAGGAAGAAGAGGAGAGGGGAGAGGCCACCGTCCAGGTCTCTTGCCTCTATAGACCACAGATGACTCAAGCCATGC CAGAACCAAGCAGCCCATGCCTGGCTGTGGCGATTCAGAAGCAACGAGGGGAGCTATCCAGAGGGTCAGTGCTGAAGGTCTGGGCAGAAG ACCTGCGAGACCCAGATGACTTGGACTTCAGCAACCTGGCTTTTGATGCCCGGATTGCAAGAATAAATGCCCTAAAGGAGAGCACATATG CAATGCCTGATGGGTTCCTTGCAGCCCAAAATGATGCCAATGAGCTGCTCTGTCTCGTCAGGGCAACCAAGGAGAAGAGGGAGGAGTCAC GCCCTGAAGCGTACGACCTTACACTTTCTCAGTACAAGCAACTGTTATCCATTGAGTCCAGACAGTTGGGAAGTGCCTGTAGGAAAATGG CGATGGCTGAGAAAAGCCCGGAGGAGATGCTCCTAGCTATGACTTCCAGCTTTCAAGTGCTCTGTTGCCTAACAGAAGCTTGCATGCGAT TAGTTAAAGTCGTGAACTCAGAAACACAGCGGCAGGAAATTGTAGGGAAGATCGATGAAGTGGTCATAAATTACATTTGTCTACTGAAAG CTGCCGAAGCAGCCACTGGAAAGAACCCTGGGGACCCTAATGTTGGACTCTCGGCGCGACACTCAACCACCATGGCCGCTCTCGTAAGCA CACTGACACGTTCTCTCAAGAGGCTTTTAAACAAATAAATATGGAAGTCACGTCATAATCTACCTTTGCAAAGCCATACATGAACTTTTA TTTACTTTGTGTGTATGATGAACAGATGTCTCCTTTCTTCTCTCTGTATATTTTGTTATTTTATATAAAATAGGAGATAAAAGTCACATT GATGAAATGTTGAAATGTACTAATCAGATGTATTCTGTTTATATTATACATATATATACACGTAAAAGAAATATCCAAGAAAGTGATGAC ATTTGGCTATTTTTCATATAGTTAAAACTCCAGGTATATGATGTGAAATTTTAAATTCTACCATGTTAGAGCAAAACAATGAATCCTATC CCCTTTCTTTCCAAGTAGCTACTTGGAAACCATATCATTCATATTTAGAAGTAAAACACAAAACAAAAAAGAGAGAGAAAAGAAAAGAAA TCACAATGTATATAAAACAGTACTTATGTTTTAAAATTATGATTTTTAAGCATTGGAAATAGCAAAAAGACATTTAAAATTCAAGAAGCT ATTATGAATTACTAGAGAATATATCTGTAATAAATTAATTTTTTGCTCATAGTATTTGGTTACTGGATGCTTTCTTCCAAGAATCCCACA TATTTAATTTGGGTTTTTGCTACTGGGGCTACAAATTGGTGGGGATGGATTCTACTGTGTCAGCACAAATGCTCTTCACAGTGGTTCTAG CATTTAAAAAACTTCCCGGGGAGAAGAACAGAGGGGATGATGGGCAGTTTCCTAGGTAACACCTAGAGTTATAGAATATCTCATTACATA AAATGTATGGAATTAATAATACCAAAATTAATTATTTGATGGAAAGATCTGCTTTGACTAAATGTCAAAAATCTGCAAACCAAAGACATT ATCTTCCCCTCATCCCAACTCAACTACGAAACTTAAAATTCCCTTTAGAGTGATAGGACATTTAGTAAAGTATTTGCAAACTTAAAAAAA GGAACATTTAATGATCATCAAAATTAAGTACAGATTCAGTAATGTAGACCAGACCACACACCAGCACCTGTGAGTCTCATCTCAGATCAC AGCTCTCAGCATAGGGCTTCATGCATCACCGCCTCTACAGAGGCTAAGGCTGCCAGTCAAATTTGGAATTATAGCGTAGTACTGGGACAA AATCTCAAATCTTGGATGTTCCAGAAAATCAGGGAGAGATGGCTACTGTAATCATGGGAGCCATGAGTAAATAGTTAAGTATTTATTAAA TAAATACTTAATCTGGATTGGCTGATAAAAATATGAAATCTGAAAAAAAAAAGAAAGAAATGGAAGTGGTATATTTGACCAGTTCAAGTG AAACCAATGGAATGCAAAGAACTTTCCAGGACTGTCACATCTCTAAAAGTACCCTGCAGTCATAAAATAAAATCGATATGTATATATGTA TTTCCTGGGTCATTCAGTGCTCAAGTTACATGCACTCCTACTTAGACAGGTGGCTCCTTAAGAACATGATGGGAGTACACCAGGTGCAAA TATTTCTACTTTTGTAGCCTGCTGAGAAGGAGTCATAACACAGTCCACAATTGCAATCTCTCTCTAGTCAGCCATTCCACAGGGACTCAA CAACAAAAGCCGCACGTGGTTATGGATGGCAGCAAAGGAAAGGAGTTTAGGTGTGTGTTATTATAAATAATGTTTAACTAAATAATAAAA CATTATTTCATTACAATTATAATTATAAATATTGGTGTTTTGATATTGAGAGATATTAGTGGTGTTTACTGTGGAAAATCTTAGTAAATA TCATTCTGTGTACTAAAATCCTAACCTATTAATAGGATGTGTGCCCTATGTCAGACAGTGTGCTAAGCATATTAACTATATTATCTCATT TAATCATCACAACAATCTGCTGGTTTGGACACTATTCTCTCTGGAGGCAATATGGATGAGTTCTTACGGATATGGGGTTTGGGGTCAGAA ACATCTTGATTAAAATTTTGACTCTGCCATTTTCTAGCCCTTTTATGTTGGGAAAGCTACTTTTTCTAGTCTCAATTTCCTCATAATAAA ATGAAAATCAATTATAAGATCGATTTCCATAGGGTTGTCATGAGTTTTGAGTAAAAATGTGTATGTAAAGTTCTTACCACAATACCTGGC AGAGAGTAAGTATTCAATTAATGTTAGCTATTATTATCATCATAATCGTTGTGTTAAATATATTGCCCAAGATAATATGTGGGGGAATGT TTGTTTTATATGCATATTGTATCCTGACTGTGTGCAGAACACATTATGTGTATTGCATATATGTAAAAGAAGTGTACAAGGAAGTGGCCA TCCTTGTTCAAGTTACGTATCTAGTTAGAACAACTTCCCAGTCCATTGGAGTTCTTTGAGAAGCCTCAGGGAAGTAGCTCTGGGTCCTTC TAATCAACCTCCCATTACTGCGCCAGTAAGTTTCTGTTTCTTATAAATAAACTCTTTGCTATTCAGAAAACCTCAAGGGGCCCCCACATT CACTAAGCATGGGGCTCCTAACTGGGGTCCAGGTCCATAGAGTGTAGGAAGAACATATTAGAACAATACTTGTGCTTATTTTTATCTAGC TTTTTTATGTTTGTGTATGTTTTATAATGGCATAATAGTACAATGGTACATGTACATAATTTTAAATAAATAAATGAATGAATGAATAAA >81760_81760_1_SHROOM2-FRMPD4_SHROOM2_chrX_9907406_ENST00000380913_FRMPD4_chrX_12725588_ENST00000380682_length(amino acids)=2346AA_BP=1 MPGVHGRGPGTLSGRAMEGAEPRARPERLAEAETRAADGGRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEI VGINDIGLSGFRQEAICLVKGSHKTLKLVVKRRSELGWRPHSWHATKFSDSHPELAASPFTSTSGCPSWSGRHHASSSSHDLSSSWEQTN LQRTLDHFSSLGSVDSLDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSSTPDHTLSKADTSSAENILYTVGLWEAPRQGGRQAQA AGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAA AAQHFTALAQAQPRGDRRPELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVRFPQSPHSGRHPPLYSD HSPLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPCVQGDLQAAQLWAGCWPSDTALGALESLPPPTVGQSPRHHLPQPE GPPDARETGRCYPLDKGAEGCSAGAQEPPRASRAEKASQRLAASITWADGESSRICPQETPLLHSLTQEGKRRPESSPEDSATRPPPFDA HVGKPTRRSDRFATTLRNEIQMHRAKLQKSRSTVALTAAGEAEDGTGRWRAGLGGGTQEGPLAGTYKDHLKEAQARVLRATSFKRRDLDP NPGDLYPESLEHRMGDPDTVPHFWEAGLAQPPSSTSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSPHQHPRTSEDTVGTF ADRWKFFEETSKPVPQRPAQKQALHGIPRDKPERPRTAGRTCEGTEPWSRTTSLGDSLNAHSAAEKAGTSDLPRRLGTFAEYQASWKEQR KPLEARSSGRCHSADDILDVSLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQSTPRQADAQCREGS PGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQR PPPPKREPRRYRATDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALLPP KQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEK DQIKTLSTSEQFYSRFCLYTRQGAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELAREIVGKDKSLADIL DPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLLPKIPSPRSTEERKEEPSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEED SGSDLDHDLSVKKQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFSEEESLVRVELHVLDVKPITLLMESSDAMNLAC LTAGYYRLLVDSRRSIFNMANKKNTATQETGPENKGKHNLLGPDWNCIPQMTTFIGEGEQEAQITYIDSKQKTVEITDSTMCPKEHRHLY IDNAYSSDGLNQQLSQPGEAPCEADYRSLAQRSLLTLSGPETLKKAQESPRGAKVSFIFGDFALDDGISPPTLGYETLLDEGPEMLEKQR NLYIGSANDMKGLDLTPEAEGIQFVENSVYANIGDVKSFQAAEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVGEMNQPAILNLSGS SDDIIDLTSLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDSQSQAASFPEDKEKGSSLQNDEIPVSLIDAVPTSAEGKCEKGLD NAVVSTLGALEALSVSEEQQTSDNSGVAILRAYSPESSSDSGNETNSSEMTESSELATAQKQSENLSRMFLATHEGYHPLAEEQTEFPAS KTPAGGLPPKSSHALAARPATDLPPKVVPSKQLLHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLADGEGKAPPNGNTTG KKQQGTKTAEMEEEASGKFGTVSSRDSQHLSTFNLERTAFRKDSQRWYVATEGGMAEKSGLEAATGKTFPRASGLGAREAEGKEEGAPDG ETSDGSGLGQGDRFLTDVTCASSAKDLDNPEDADSSTCDHPSKLPEADESVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDAGCGTGS SGSACATPVESPLCPSLGKHLIPDASGKGVNYIPSEERAPGLPNHGATFKELHPQTEGMCPRMTVPALHTAINTEPLFGTLRDGCHRLPK -------------------------------------------------------------- >81760_81760_2_SHROOM2-FRMPD4_SHROOM2_chrX_9907406_ENST00000418909_FRMPD4_chrX_12725588_ENST00000380682_length(transcript)=8308nt_BP=1636nt AAATGCAAGCGGAGCCTTGAGCCGTGGAGGTGAAGGTTGACGGAGCCTGCGTGAGCTTGCCCATCAACAAGACAGCAGGCACAGACAGGC CAGCTGTTGTGAGCTTGGCTTTAGGACTCCATTCAGTAGGCAGGAGGAGAGCTGCAGCAGAGGCGGGCTGTGGGTCCCTGAAGCACATCG CTGCCTTCACAGCTGGGCGAACTCCCATCCAGCACGACAAGCAGATGCCCAGTGTCGGGAAGGCAGCCCAGGATCACAGCAGCACCCACC GAGTCAGAAGGCACCGAACCCACCCACATTCTCTGAACTATCTCACTGCCGGGGAGCCCCAGAGCTGCCCCGGGAGGGCCGGGGCCGAGC GGGAACCCTACCTCGAGATTATAGATACTCGGAGGAGAGCACCCCAGCAGACTTGGGACCCCGAGCCCAGAGCCCTGGCTCACCCCTGCA TGCTCGAGGACAAGACTCGTGGCCAGTGAGCTCAGCCCTGCTCTCCAAGAGGCCAGCCCCACAGAGGCCACCGCCACCCAAGCGCGAGCC CAGGAGATACAGGGCCACAGACGGCGCACCTGCTGACGCCCCCGTGGGCGTCCTCGGCAGGCCCTTCCCAACGCCATCCCCTGCGTCCCT GGATGTGTATGTGGCCCGCCTGTCCCTCTCCCACAGCCCCTCTGTGTTCAGCAGTGCCCAGCCCCAGGACACCCCGAAGGCCACTGTCTG TGAGCGTGGAAGCCAGCATGTGAGCGGGGACGCATCACGTCCTCTGCCAGAAGCACTGCTCCCTCCCAAGCAGCAGCACCTGCGCCTGCA GACGGCCACCATGGAGACCTCGCGCTCCCCCTCGCCCCAGTTCGCCCCCCAGAAACTGACGGACAAACCTCCCCTGCTCATCCAGGATGA GGATTCAACCAGAATTGAGCGGGTGATGGACAACAACACCACGGTGAAGATGGTGCCCATCAAGATCGTGCACTCGGAGAGCCAGCCAGA GAAGGAGAGCCGCCAGAGCCTGGCATGCCCCGCCGAGCCACCTGCCCTGCCCCACGGGCTGGAGAAAGACCAGATCAAGACGCTGAGCAC ATCTGAGCAGTTCTACTCGCGCTTCTGTCTGTACACGCGGCAGGGTGCTGAGCCCGAGGCCCCACATAGGGCCCAGCCGGCTGAGCCCCA GCCCCTGGGCACCCAGGTGCCCCCCGAGAAAGACCGCTGCACCTCCCCTCCAGGGCTCAGCTACATGAAGGCCAAAGAGAAGACTGTGGA AGACCTGAAGTCGGAGGAGCTGGCCAGGGAGATCGTGGGGAAGGATAAGTCCCTGGCCGACATCCTGGATCCCAGTGTGAAGATCAAAAC CACTATGGACTTGATGGAAGGCATCTTCCCCAAAGACGAGCACCTCCTGGAAGAAGCCCAGCAACGGAGGAAGCTGCTCCCCAAAATCCC CTCTCCTAGAAGCACAGAGGAGAGGAAAGAGGAGCCCAGCGTGCCTGCGGCCGTGTCCCTGGCCACCAATTCTACCTACTACAGCACGTC GGCCCCCAAGGCGGAGCTGCTGATCAAGATGAAGGACCTGCAGGAGCAGCAGGAGCACGAAGAGGATTCGGGAAGCGACTTGGACCACGA CCTGTCGGTGAAGAAGCAGGCAGAAAAGCGCTCGGAAGTGACTCTCCTGGTTGGGCCCCGGTATGGCATAAGCCATGTCATCAACACCAA AACCAATCTGGTGGCTCTTTTAGCCGACTTTAGCCACGTCAACAGGATCGAAATGTTTTCCGAGGAGGAGAGCTTGGTGCGGGTAGAACT CCACGTGCTAGATGTGAAGCCTATCACGCTTCTGATGGAATCCTCAGATGCCATGAACCTGGCCTGCTTGACGGCTGGATACTACCGGCT GCTTGTTGATTCCAGGAGGTCGATATTTAACATGGCCAACAAGAAAAACACAGCGACCCAGGAAACAGGACCTGAAAACAAGGGGAAGCA TAACCTCCTTGGCCCAGATTGGAACTGTATACCCCAAATGACCACCTTTATTGGCGAAGGGGAACAAGAAGCCCAGATAACATACATAGA TTCAAAGCAGAAGACGGTGGAGATCACAGACAGCACCATGTGTCCAAAAGAGCACCGGCACTTGTACATAGACAATGCCTATAGTTCAGA TGGACTTAACCAGCAGCTGAGCCAGCCCGGGGAGGCCCCCTGTGAGGCAGACTACAGAAGTCTAGCTCAGCGGTCCCTATTGACCCTCTC AGGACCAGAAACTCTGAAGAAAGCACAGGAATCTCCGAGAGGAGCTAAAGTGTCCTTTATTTTTGGAGACTTCGCCTTGGATGATGGTAT TAGTCCCCCAACCCTTGGCTATGAAACGCTACTAGATGAGGGTCCTGAAATGCTGGAGAAGCAGAGAAATCTCTACATTGGCAGTGCCAA TGACATGAAGGGCCTGGATCTCACTCCAGAGGCAGAGGGCATCCAGTTTGTGGAAAATTCTGTTTATGCAAACATAGGCGATGTGAAGAG CTTCCAGGCCGCGGAGGGGATCGAGGAACCCCTCTTGCATGACATCTGTTATGCAGAAAACACTGATGACGCGGAGGACGAGGACGAGGT GAGCTGCGAGGAGGACCTCGTGGTGGGGGAGATGAACCAGCCGGCCATCCTCAACCTGTCTGGGTCAAGCGATGACATCATTGACCTCAC ATCCCTGCCCCCTCCAGAAGGTGATGACAATGAGGATGACTTCCTGTTGCGTTCCTTGAACATGGCCATTGCCGCACCCCCACCTGGCTT TAGAGACAGTTCAGATGAAGAGGACTCTCAGAGCCAGGCAGCTTCCTTCCCCGAGGACAAGGAGAAAGGCAGCAGCCTGCAAAATGATGA GATCCCCGTGTCCCTCATTGACGCTGTGCCCACCAGCGCCGAAGGCAAGTGTGAGAAGGGACTGGATAATGCCGTCGTCTCCACGCTGGG AGCTCTAGAGGCTCTATCCGTGTCAGAAGAACAGCAGACCAGTGACAATTCAGGTGTAGCCATCTTGCGGGCTTATAGTCCTGAGTCTTC GTCAGACTCGGGCAATGAAACTAACTCTTCTGAAATGACTGAGAGTTCTGAACTGGCCACAGCACAAAAACAGTCAGAAAACCTCTCCCG CATGTTCTTGGCCACTCACGAAGGCTACCACCCCCTTGCAGAAGAGCAGACCGAGTTCCCGGCCTCCAAGACCCCCGCTGGGGGCTTGCC TCCAAAGTCCTCGCACGCCCTGGCTGCTAGGCCAGCAACCGACCTCCCGCCCAAAGTTGTGCCTTCCAAGCAGTTACTTCACTCAGACCA CATGGAGATGGAGCCTGAAACTATGGAGACTAAGTCGGTCACTGACTATTTTAGCAAACTGCACATGGGGTCGGTGGCATACTCCTGCAC TAGCAAAAGGAAAAGCAAGCTGGCCGATGGTGAGGGGAAGGCACCCCCTAATGGGAACACAACAGGAAAAAAACAGCAGGGGACCAAAAC GGCAGAGATGGAGGAGGAGGCCAGTGGTAAATTTGGTACTGTGTCTTCACGAGACAGTCAACACCTGAGCACTTTTAATCTGGAGAGAAC TGCCTTTCGCAAGGACAGTCAAAGATGGTATGTGGCCACTGAAGGTGGGATGGCTGAAAAAAGTGGATTAGAAGCAGCAACAGGGAAAAC CTTTCCAAGAGCTTCTGGTCTTGGGGCAAGGGAGGCCGAAGGGAAGGAAGAAGGAGCTCCTGATGGAGAAACCAGTGATGGCTCAGGACT TGGTCAAGGGGACCGCTTCTTAACTGACGTGACCTGTGCATCTTCAGCCAAAGACTTAGATAACCCAGAGGACGCTGACTCGTCCACCTG CGACCATCCTTCCAAGCTTCCTGAGGCTGATGAGAGTGTGGCCCGCCTTTGTGACTACCACTTGGCCAAGCGGATGTCATCACTGCAAAG CGAGGGCCATTTTTCTCTGCAGAGCTCCCAAGGCTCTTCAGTGGATGCAGGCTGTGGCACAGGCAGCAGTGGCAGTGCCTGTGCCACACC CGTGGAGTCGCCGCTCTGCCCCTCCCTGGGGAAGCACTTGATTCCTGACGCTTCTGGGAAAGGCGTGAATTACATTCCTTCAGAGGAGAG AGCCCCTGGGCTTCCCAACCACGGAGCCACCTTTAAGGAACTGCACCCACAGACAGAAGGGATGTGTCCACGGATGACAGTGCCTGCTCT GCACACAGCCATTAACACCGAACCCCTGTTTGGCACATTGAGAGATGGATGCCATCGGCTCCCCAAGATTAAGGAAACCACAGTGTAGCT TTGACAGAGCCTGGGAAGGAGAGACGAGGAGGCATGCCTTCAGCTTGGTCTCAACATCCTGAAGCTGATCCCATCCTGCTACCATCAAAC ATTCACTCGGAATCAAAGGTGCCAATTCCAAATCAAGACCCTAATGATTTCTCCCAAGCAAATCAGGCATACGGAGAGGCTGTGAGCTGG CGGCCACCGGATCTGAGAGGGGGGAGCCTCAGGACACCTCCCAGCCAGAAGGCTCTGAGACATAGCAGCAGTATCCTCTCCGGATCTGTC GATTTGGAGACCTTCCGAGAGAGAACCAAGGGTGCAGTCAGCTTAAAGTGTCCAGGCATCACAGAAGCACAGGAGGCCAGTTCTGAAAGG CGAGCAGAACTCCCCCTGGGGAGGAAGCTCACCAAAAGTTTTTCCCAAAGCTCAATGCACTTGAGCTCTGAGGGGAGGTTTCACAAAAGG TCCCCAGTGGCTCATAAAGACTCAAAGCTGTATAGGACATTACCCTTGCGGAAGCTGGAGGGCAGCAATTGGAGATGCCGGGGACCCTTC AGCTATTGCTTCCTGAACCGAGGGCAGGATGAAGATGGTGAGGAAGAAGAGGAGAGGGGAGAGGCCACCGTCCAGGTCTCTTGCCTCTAT AGACCACAGATGACTCAAGCCATGCCAGAACCAAGCAGCCCATGCCTGGCTGTGGCGATTCAGAAGCAACGAGGGGAGCTATCCAGAGGG TCAGTGCTGAAGGTCTGGGCAGAAGACCTGCGAGACCCAGATGACTTGGACTTCAGCAACCTGGCTTTTGATGCCCGGATTGCAAGAATA AATGCCCTAAAGGAGAGCACATATGCAATGCCTGATGGGTTCCTTGCAGCCCAAAATGATGCCAATGAGCTGCTCTGTCTCGTCAGGGCA ACCAAGGAGAAGAGGGAGGAGTCACGCCCTGAAGCGTACGACCTTACACTTTCTCAGTACAAGCAACTGTTATCCATTGAGTCCAGACAG TTGGGAAGTGCCTGTAGGAAAATGGCGATGGCTGAGAAAAGCCCGGAGGAGATGCTCCTAGCTATGACTTCCAGCTTTCAAGTGCTCTGT TGCCTAACAGAAGCTTGCATGCGATTAGTTAAAGTCGTGAACTCAGAAACACAGCGGCAGGAAATTGTAGGGAAGATCGATGAAGTGGTC ATAAATTACATTTGTCTACTGAAAGCTGCCGAAGCAGCCACTGGAAAGAACCCTGGGGACCCTAATGTTGGACTCTCGGCGCGACACTCA ACCACCATGGCCGCTCTCGTAAGCACACTGACACGTTCTCTCAAGAGGCTTTTAAACAAATAAATATGGAAGTCACGTCATAATCTACCT TTGCAAAGCCATACATGAACTTTTATTTACTTTGTGTGTATGATGAACAGATGTCTCCTTTCTTCTCTCTGTATATTTTGTTATTTTATA TAAAATAGGAGATAAAAGTCACATTGATGAAATGTTGAAATGTACTAATCAGATGTATTCTGTTTATATTATACATATATATACACGTAA AAGAAATATCCAAGAAAGTGATGACATTTGGCTATTTTTCATATAGTTAAAACTCCAGGTATATGATGTGAAATTTTAAATTCTACCATG TTAGAGCAAAACAATGAATCCTATCCCCTTTCTTTCCAAGTAGCTACTTGGAAACCATATCATTCATATTTAGAAGTAAAACACAAAACA AAAAAGAGAGAGAAAAGAAAAGAAATCACAATGTATATAAAACAGTACTTATGTTTTAAAATTATGATTTTTAAGCATTGGAAATAGCAA AAAGACATTTAAAATTCAAGAAGCTATTATGAATTACTAGAGAATATATCTGTAATAAATTAATTTTTTGCTCATAGTATTTGGTTACTG GATGCTTTCTTCCAAGAATCCCACATATTTAATTTGGGTTTTTGCTACTGGGGCTACAAATTGGTGGGGATGGATTCTACTGTGTCAGCA CAAATGCTCTTCACAGTGGTTCTAGCATTTAAAAAACTTCCCGGGGAGAAGAACAGAGGGGATGATGGGCAGTTTCCTAGGTAACACCTA GAGTTATAGAATATCTCATTACATAAAATGTATGGAATTAATAATACCAAAATTAATTATTTGATGGAAAGATCTGCTTTGACTAAATGT CAAAAATCTGCAAACCAAAGACATTATCTTCCCCTCATCCCAACTCAACTACGAAACTTAAAATTCCCTTTAGAGTGATAGGACATTTAG TAAAGTATTTGCAAACTTAAAAAAAGGAACATTTAATGATCATCAAAATTAAGTACAGATTCAGTAATGTAGACCAGACCACACACCAGC ACCTGTGAGTCTCATCTCAGATCACAGCTCTCAGCATAGGGCTTCATGCATCACCGCCTCTACAGAGGCTAAGGCTGCCAGTCAAATTTG GAATTATAGCGTAGTACTGGGACAAAATCTCAAATCTTGGATGTTCCAGAAAATCAGGGAGAGATGGCTACTGTAATCATGGGAGCCATG AGTAAATAGTTAAGTATTTATTAAATAAATACTTAATCTGGATTGGCTGATAAAAATATGAAATCTGAAAAAAAAAAGAAAGAAATGGAA GTGGTATATTTGACCAGTTCAAGTGAAACCAATGGAATGCAAAGAACTTTCCAGGACTGTCACATCTCTAAAAGTACCCTGCAGTCATAA AATAAAATCGATATGTATATATGTATTTCCTGGGTCATTCAGTGCTCAAGTTACATGCACTCCTACTTAGACAGGTGGCTCCTTAAGAAC ATGATGGGAGTACACCAGGTGCAAATATTTCTACTTTTGTAGCCTGCTGAGAAGGAGTCATAACACAGTCCACAATTGCAATCTCTCTCT AGTCAGCCATTCCACAGGGACTCAACAACAAAAGCCGCACGTGGTTATGGATGGCAGCAAAGGAAAGGAGTTTAGGTGTGTGTTATTATA AATAATGTTTAACTAAATAATAAAACATTATTTCATTACAATTATAATTATAAATATTGGTGTTTTGATATTGAGAGATATTAGTGGTGT TTACTGTGGAAAATCTTAGTAAATATCATTCTGTGTACTAAAATCCTAACCTATTAATAGGATGTGTGCCCTATGTCAGACAGTGTGCTA AGCATATTAACTATATTATCTCATTTAATCATCACAACAATCTGCTGGTTTGGACACTATTCTCTCTGGAGGCAATATGGATGAGTTCTT ACGGATATGGGGTTTGGGGTCAGAAACATCTTGATTAAAATTTTGACTCTGCCATTTTCTAGCCCTTTTATGTTGGGAAAGCTACTTTTT CTAGTCTCAATTTCCTCATAATAAAATGAAAATCAATTATAAGATCGATTTCCATAGGGTTGTCATGAGTTTTGAGTAAAAATGTGTATG TAAAGTTCTTACCACAATACCTGGCAGAGAGTAAGTATTCAATTAATGTTAGCTATTATTATCATCATAATCGTTGTGTTAAATATATTG CCCAAGATAATATGTGGGGGAATGTTTGTTTTATATGCATATTGTATCCTGACTGTGTGCAGAACACATTATGTGTATTGCATATATGTA AAAGAAGTGTACAAGGAAGTGGCCATCCTTGTTCAAGTTACGTATCTAGTTAGAACAACTTCCCAGTCCATTGGAGTTCTTTGAGAAGCC TCAGGGAAGTAGCTCTGGGTCCTTCTAATCAACCTCCCATTACTGCGCCAGTAAGTTTCTGTTTCTTATAAATAAACTCTTTGCTATTCA GAAAACCTCAAGGGGCCCCCACATTCACTAAGCATGGGGCTCCTAACTGGGGTCCAGGTCCATAGAGTGTAGGAAGAACATATTAGAACA ATACTTGTGCTTATTTTTATCTAGCTTTTTTATGTTTGTGTATGTTTTATAATGGCATAATAGTACAATGGTACATGTACATAATTTTAA >81760_81760_2_SHROOM2-FRMPD4_SHROOM2_chrX_9907406_ENST00000418909_FRMPD4_chrX_12725588_ENST00000380682_length(amino acids)=1423AA_BP=1 MRELAHQQDSRHRQASCCELGFRTPFSRQEESCSRGGLWVPEAHRCLHSWANSHPARQADAQCREGSPGSQQHPPSQKAPNPPTFSELSH CRGAPELPREGRGRAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDGAPADAPV GVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFA PQKLTDKPPLLIQDEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRFCLYTRQG AEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHL LEEAQQRRKLLPKIPSPRSTEERKEEPSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEEDSGSDLDHDLSVKKQAEKRSEVTL LVGPRYGISHVINTKTNLVALLADFSHVNRIEMFSEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKK NTATQETGPENKGKHNLLGPDWNCIPQMTTFIGEGEQEAQITYIDSKQKTVEITDSTMCPKEHRHLYIDNAYSSDGLNQQLSQPGEAPCE ADYRSLAQRSLLTLSGPETLKKAQESPRGAKVSFIFGDFALDDGISPPTLGYETLLDEGPEMLEKQRNLYIGSANDMKGLDLTPEAEGIQ FVENSVYANIGDVKSFQAAEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVGEMNQPAILNLSGSSDDIIDLTSLPPPEGDDNEDDFL LRSLNMAIAAPPPGFRDSSDEEDSQSQAASFPEDKEKGSSLQNDEIPVSLIDAVPTSAEGKCEKGLDNAVVSTLGALEALSVSEEQQTSD NSGVAILRAYSPESSSDSGNETNSSEMTESSELATAQKQSENLSRMFLATHEGYHPLAEEQTEFPASKTPAGGLPPKSSHALAARPATDL PPKVVPSKQLLHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLADGEGKAPPNGNTTGKKQQGTKTAEMEEEASGKFGTVS SRDSQHLSTFNLERTAFRKDSQRWYVATEGGMAEKSGLEAATGKTFPRASGLGAREAEGKEEGAPDGETSDGSGLGQGDRFLTDVTCASS AKDLDNPEDADSSTCDHPSKLPEADESVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDAGCGTGSSGSACATPVESPLCPSLGKHLIP -------------------------------------------------------------- >81760_81760_3_SHROOM2-FRMPD4_SHROOM2_chrX_9912953_ENST00000380913_FRMPD4_chrX_12724945_ENST00000380682_length(transcript)=11436nt_BP=4674nt TCTGCGGCGCTCGGAGCCTCCCTTGCGATCCCACGGCCGGGACTGCCCGGAGTGCATGGGCGCGGGCCAGGGACGCTGAGCGGTCGCGCC ATGGAGGGCGCCGAGCCCCGCGCGCGGCCCGAGCGCCTGGCCGAGGCCGAGACGCGGGCGGCGGACGGCGGGCGCCTGGTGGAGGTGCAG CTGAGCGGCGGCGCCCCGTGGGGCTTCACCCTGAAGGGCGGCCGCGAGCACGGCGAGCCGCTGGTCATCACCAAGATTGAAGAGGGCAGT AAAGCCGCGGCGGTCGACAAGTTACTGGCTGGAGATGAGATCGTCGGCATCAATGACATTGGTCTCTCAGGGTTTAGACAGGAAGCGATT TGCCTGGTGAAGGGGTCCCATAAGACCCTGAAGCTGGTCGTCAAAAGGAGGAGCGAGCTGGGCTGGAGGCCTCACTCCTGGCATGCCACC AAGTTCTCTGACAGCCACCCCGAGCTAGCGGCCTCCCCATTCACCTCCACCAGCGGCTGTCCTTCCTGGTCCGGCCGACACCACGCGAGT TCTTCCTCCCACGACCTGTCCAGTTCCTGGGAGCAGACGAACCTACAGCGCACCTTAGATCACTTCAGCTCCTTGGGGAGCGTTGACAGC CTGGACCACCCCTCCAGTCGCCTCTCGGTGGCCAAGTCCAACAGCAGCATCGACCACCTGGGCAGCCACAGCAAGCGCGACTCGGCCTAC GGCTCCTTCTCCACCAGCTCTAGCACTCCTGACCACACCTTGTCCAAAGCCGACACGTCCTCCGCAGAGAACATCCTCTACACTGTGGGC CTCTGGGAGGCTCCCAGGCAGGGTGGCCGGCAGGCCCAGGCCGCAGGCGACCCTCAGGGCTCGGAGGAGAAGCTCAGTTGTTTCCCGCCC AGGGTCCCCGGTGACAGCGGCAAAGGCCCCAGGCCAGAGTACAATGCCGAGCCCAAGCTGGCTGCCCCTGGGAGGTCCAATTTTGGGCCA GTCTGGTATGTTCCCGATAAGAAGAAAGCACCATCATCCCCACCTCCTCCCCCTCCCCCTCTCCGCAGTGACAGCTTTGCTGCCACCAAG AGCCACGAGAAGGCCCAGGGCCCTGTGTTCTCAGAGGCGGCTGCGGCACAGCACTTTACGGCCCTGGCCCAGGCTCAGCCTCGTGGTGAC CGGAGACCAGAGCTCACCGATCGGCCTTGGAGGTCAGCACACCCGGGGAGCCTCGGGAAGGGATCGGGAGGCCCGGGCTGCCCACAGGAG GCCCACGCAGACGGCAGCTGGCCGCCCTCCAAGGATGGAGCTTCCAGTAGGCTGCAGGCCTCTCTGTCCAGCTCAGATGTGCGCTTCCCT CAGTCTCCTCATAGCGGCCGACACCCTCCCCTATACAGCGACCACAGCCCCCTCTGTGCTGACAGCCTTGGGCAGGAGCCAGGGGCTGCC AGCTTCCAGAACGACAGCCCTCCTCAGGTGAGGGGGCTCAGCAGCTGTGACCAGAAGCTGGGGAGCGGCTGGCAGGGTCCCCGGCCCTGT GTGCAGGGAGACCTGCAAGCAGCACAGCTCTGGGCGGGATGCTGGCCTTCTGACACAGCCCTTGGAGCCCTCGAGAGTCTTCCCCCACCC ACGGTGGGCCAGAGCCCACGCCATCACCTACCTCAGCCTGAGGGTCCTCCGGATGCCCGCGAGACAGGACGGTGTTACCCGCTGGACAAA GGGGCCGAGGGCTGCTCCGCGGGAGCCCAGGAGCCTCCCAGGGCCAGCCGTGCAGAAAAAGCCAGCCAGAGGCTGGCAGCCAGCATCACG TGGGCAGATGGGGAGAGCAGCAGGATCTGCCCGCAGGAGACGCCCCTGTTGCACTCCCTGACCCAGGAGGGGAAGCGCCGGCCTGAGAGC AGTCCAGAGGACAGCGCCACCAGACCGCCACCGTTCGACGCCCACGTGGGCAAGCCCACCCGAAGAAGCGACCGCTTTGCCACCACCCTG CGGAATGAGATCCAGATGCATAGAGCCAAGCTGCAGAAGAGCCGGAGCACAGTGGCTCTGACTGCAGCAGGGGAGGCGGAGGATGGCACC GGCCGCTGGAGGGCCGGGTTGGGAGGTGGCACCCAGGAAGGACCCCTCGCTGGCACCTATAAAGACCACCTGAAAGAGGCCCAAGCCCGG GTCCTGAGGGCCACGTCCTTCAAGCGCCGCGACTTGGACCCCAACCCAGGAGACCTATACCCGGAGTCACTGGAACACCGGATGGGGGAT CCAGACACTGTCCCCCACTTCTGGGAGGCAGGCCTGGCCCAGCCACCCTCATCTACAAGTGGCGGGCCCCACCCGCCCCGCATCGGAGGC CGGAGACGGTTCACAGCTGAGCAGAAATTGAAGTCCTACTCGGAACCTGAGAAGATGAACGAGGTGGGCCTCACGAGGGGCTACAGTCCT CACCAGCACCCCAGGACATCTGAGGATACTGTGGGCACGTTTGCTGACAGGTGGAAGTTTTTTGAGGAAACGAGCAAACCTGTTCCCCAG AGGCCTGCCCAGAAGCAAGCTCTTCACGGAATCCCGAGAGACAAGCCAGAGAGGCCGCGGACAGCGGGCCGCACATGTGAGGGCACGGAG CCCTGGTCGCGCACCACCTCCCTTGGGGACAGCCTCAACGCTCACAGCGCAGCGGAGAAGGCAGGGACTTCAGACCTGCCGCGGAGGCTC GGCACCTTTGCAGAGTATCAGGCCTCTTGGAAGGAACAGAGGAAACCTCTGGAGGCCAGGAGCTCTGGGCGCTGCCACTCAGCGGATGAC ATCCTGGATGTGAGCCTGGACCCACAGGAGAGGCCGCAGCACGTTCATGGGAGGTCCCGGTCTTCACCGTCCACAGACCACTACAAGCAG GAAGCTTCTGTCGAACTGCGAAGGCAGGCAGGGGACCCCGGCGAGCCCAGAGAAGAGCTTCCCTCCGCAGTCCGGGCCGAGGAGGGACAG TCCACGCCGAGACAAGCAGATGCCCAGTGTCGGGAAGGCAGCCCAGGATCACAGCAGCACCCACCGAGTCAGAAGGCACCGAACCCACCC ACATTCTCTGAACTATCTCACTGCCGGGGAGCCCCAGAGCTGCCCCGGGAGGGCCGGGGCCGAGCGGGAACCCTACCTCGAGATTATAGA TACTCGGAGGAGAGCACCCCAGCAGACTTGGGACCCCGAGCCCAGAGCCCTGGCTCACCCCTGCATGCTCGAGGACAAGACTCGTGGCCA GTGAGCTCAGCCCTGCTCTCCAAGAGGCCAGCCCCACAGAGGCCACCGCCACCCAAGCGCGAGCCCAGGAGATACAGGGCCACAGACGGC GCACCTGCTGACGCCCCCGTGGGCGTCCTCGGCAGGCCCTTCCCAACGCCATCCCCTGCGTCCCTGGATGTGTATGTGGCCCGCCTGTCC CTCTCCCACAGCCCCTCTGTGTTCAGCAGTGCCCAGCCCCAGGACACCCCGAAGGCCACTGTCTGTGAGCGTGGAAGCCAGCATGTGAGC GGGGACGCATCACGTCCTCTGCCAGAAGCACTGCTCCCTCCCAAGCAGCAGCACCTGCGCCTGCAGACGGCCACCATGGAGACCTCGCGC TCCCCCTCGCCCCAGTTCGCCCCCCAGAAACTGACGGACAAACCTCCCCTGCTCATCCAGGATGAGGATTCAACCAGAATTGAGCGGGTG ATGGACAACAACACCACGGTGAAGATGGTGCCCATCAAGATCGTGCACTCGGAGAGCCAGCCAGAGAAGGAGAGCCGCCAGAGCCTGGCA TGCCCCGCCGAGCCACCTGCCCTGCCCCACGGGCTGGAGAAAGACCAGATCAAGACGCTGAGCACATCTGAGCAGTTCTACTCGCGCTTC TGTCTGTACACGCGGCAGGGTGCTGAGCCCGAGGCCCCACATAGGGCCCAGCCGGCTGAGCCCCAGCCCCTGGGCACCCAGGTGCCCCCC GAGAAAGACCGCTGCACCTCCCCTCCAGGGCTCAGCTACATGAAGGCCAAAGAGAAGACTGTGGAAGACCTGAAGTCGGAGGAGCTGGCC AGGGAGATCGTGGGGAAGGATAAGTCCCTGGCCGACATCCTGGATCCCAGTGTGAAGATCAAAACCACTATGGACTTGATGGAAGGCATC TTCCCCAAAGACGAGCACCTCCTGGAAGAAGCCCAGCAACGGAGGAAGCTGCTCCCCAAAATCCCCTCTCCTAGAAGCACAGAGGAGAGG AAAGAGGAGCCCAGCGTGCCTGCGGCCGTGTCCCTGGCCACCAATTCTACCTACTACAGCACGTCGGCCCCCAAGGCGGAGCTGCTGATC AAGATGAAGGACCTGCAGGAGCAGCAGGAGCACGAAGAGGATTCGGGAAGCGACTTGGACCACGACCTGTCGGTGAAGAAGCAGGAGCTC ATCGAGAGCATCAGCCGCAAGCTGCAGGTGCTCCGGGAGGCCCGCGAGAGCCTGCTGGAGGACGTGCAGGCCAACACCGTGCTGGGGGCC GAGGTGGAGGCCATCGTGAAAGGCGTCTGCAAGCCCAGCGAGTTTGACAAGTTCCGGATGTTCATTGGAGACCTGGACAAAGTGGTGAAC CTCCTGCTGTCGCTGTCAGGCCGCCTGGCCCGGGTGGAGAATGCCCTCAATAATTTGGACGACGGCGCTTCTCCCGGTGATCGGCTCTCT GCACTACAAGCCAAGGTCCATTATCTCAAGTTCCTCAGTGACCTACGATTGTATGGGGGCCGTGTGTTCAAGGCAACATTAGTGCAGGCA GAAAAGCGCTCGGAAGTGACTCTCCTGGTTGGGCCCCGGTATGGCATAAGCCATGTCATCAACACCAAAACCAATCTGGTGGCTCTTTTA GCCGACTTTAGCCACGTCAACAGGATCGAAATGTTTTCCGAGGAGGAGAGCTTGGTGCGGGTAGAACTCCACGTGCTAGATGTGAAGCCT ATCACGCTTCTGATGGAATCCTCAGATGCCATGAACCTGGCCTGCTTGACGGCTGGATACTACCGGCTGCTTGTTGATTCCAGGAGGTCG ATATTTAACATGGCCAACAAGAAAAACACAGCGACCCAGGAAACAGGACCTGAAAACAAGGGGAAGCATAACCTCCTTGGCCCAGATTGG AACTGTATACCCCAAATGACCACCTTTATTGGCGAAGGGGAACAAGAAGCCCAGATAACATACATAGATTCAAAGCAGAAGACGGTGGAG ATCACAGACAGCACCATGTGTCCAAAAGAGCACCGGCACTTGTACATAGACAATGCCTATAGTTCAGATGGACTTAACCAGCAGCTGAGC CAGCCCGGGGAGGCCCCCTGTGAGGCAGACTACAGAAGTCTAGCTCAGCGGTCCCTATTGACCCTCTCAGGACCAGAAACTCTGAAGAAA GCACAGGAATCTCCGAGAGGAGCTAAAGTGTCCTTTATTTTTGGAGACTTCGCCTTGGATGATGGTATTAGTCCCCCAACCCTTGGCTAT GAAACGCTACTAGATGAGGGTCCTGAAATGCTGGAGAAGCAGAGAAATCTCTACATTGGCAGTGCCAATGACATGAAGGGCCTGGATCTC ACTCCAGAGGCAGAGGGCATCCAGTTTGTGGAAAATTCTGTTTATGCAAACATAGGCGATGTGAAGAGCTTCCAGGCCGCGGAGGGGATC GAGGAACCCCTCTTGCATGACATCTGTTATGCAGAAAACACTGATGACGCGGAGGACGAGGACGAGGTGAGCTGCGAGGAGGACCTCGTG GTGGGGGAGATGAACCAGCCGGCCATCCTCAACCTGTCTGGGTCAAGCGATGACATCATTGACCTCACATCCCTGCCCCCTCCAGAAGGT GATGACAATGAGGATGACTTCCTGTTGCGTTCCTTGAACATGGCCATTGCCGCACCCCCACCTGGCTTTAGAGACAGTTCAGATGAAGAG GACTCTCAGAGCCAGGCAGCTTCCTTCCCCGAGGACAAGGAGAAAGGCAGCAGCCTGCAAAATGATGAGATCCCCGTGTCCCTCATTGAC GCTGTGCCCACCAGCGCCGAAGGCAAGTGTGAGAAGGGACTGGATAATGCCGTCGTCTCCACGCTGGGAGCTCTAGAGGCTCTATCCGTG TCAGAAGAACAGCAGACCAGTGACAATTCAGGTGTAGCCATCTTGCGGGCTTATAGTCCTGAGTCTTCGTCAGACTCGGGCAATGAAACT AACTCTTCTGAAATGACTGAGAGTTCTGAACTGGCCACAGCACAAAAACAGTCAGAAAACCTCTCCCGCATGTTCTTGGCCACTCACGAA GGCTACCACCCCCTTGCAGAAGAGCAGACCGAGTTCCCGGCCTCCAAGACCCCCGCTGGGGGCTTGCCTCCAAAGTCCTCGCACGCCCTG GCTGCTAGGCCAGCAACCGACCTCCCGCCCAAAGTTGTGCCTTCCAAGCAGTTACTTCACTCAGACCACATGGAGATGGAGCCTGAAACT ATGGAGACTAAGTCGGTCACTGACTATTTTAGCAAACTGCACATGGGGTCGGTGGCATACTCCTGCACTAGCAAAAGGAAAAGCAAGCTG GCCGATGGTGAGGGGAAGGCACCCCCTAATGGGAACACAACAGGAAAAAAACAGCAGGGGACCAAAACGGCAGAGATGGAGGAGGAGGCC AGTGGTAAATTTGGTACTGTGTCTTCACGAGACAGTCAACACCTGAGCACTTTTAATCTGGAGAGAACTGCCTTTCGCAAGGACAGTCAA AGATGGTATGTGGCCACTGAAGGTGGGATGGCTGAAAAAAGTGGATTAGAAGCAGCAACAGGGAAAACCTTTCCAAGAGCTTCTGGTCTT GGGGCAAGGGAGGCCGAAGGGAAGGAAGAAGGAGCTCCTGATGGAGAAACCAGTGATGGCTCAGGACTTGGTCAAGGGGACCGCTTCTTA ACTGACGTGACCTGTGCATCTTCAGCCAAAGACTTAGATAACCCAGAGGACGCTGACTCGTCCACCTGCGACCATCCTTCCAAGCTTCCT GAGGCTGATGAGAGTGTGGCCCGCCTTTGTGACTACCACTTGGCCAAGCGGATGTCATCACTGCAAAGCGAGGGCCATTTTTCTCTGCAG AGCTCCCAAGGCTCTTCAGTGGATGCAGGCTGTGGCACAGGCAGCAGTGGCAGTGCCTGTGCCACACCCGTGGAGTCGCCGCTCTGCCCC TCCCTGGGGAAGCACTTGATTCCTGACGCTTCTGGGAAAGGCGTGAATTACATTCCTTCAGAGGAGAGAGCCCCTGGGCTTCCCAACCAC GGAGCCACCTTTAAGGAACTGCACCCACAGACAGAAGGGATGTGTCCACGGATGACAGTGCCTGCTCTGCACACAGCCATTAACACCGAA CCCCTGTTTGGCACATTGAGAGATGGATGCCATCGGCTCCCCAAGATTAAGGAAACCACAGTGTAGCTTTGACAGAGCCTGGGAAGGAGA GACGAGGAGGCATGCCTTCAGCTTGGTCTCAACATCCTGAAGCTGATCCCATCCTGCTACCATCAAACATTCACTCGGAATCAAAGGTGC CAATTCCAAATCAAGACCCTAATGATTTCTCCCAAGCAAATCAGGCATACGGAGAGGCTGTGAGCTGGCGGCCACCGGATCTGAGAGGGG GGAGCCTCAGGACACCTCCCAGCCAGAAGGCTCTGAGACATAGCAGCAGTATCCTCTCCGGATCTGTCGATTTGGAGACCTTCCGAGAGA GAACCAAGGGTGCAGTCAGCTTAAAGTGTCCAGGCATCACAGAAGCACAGGAGGCCAGTTCTGAAAGGCGAGCAGAACTCCCCCTGGGGA GGAAGCTCACCAAAAGTTTTTCCCAAAGCTCAATGCACTTGAGCTCTGAGGGGAGGTTTCACAAAAGGTCCCCAGTGGCTCATAAAGACT CAAAGCTGTATAGGACATTACCCTTGCGGAAGCTGGAGGGCAGCAATTGGAGATGCCGGGGACCCTTCAGCTATTGCTTCCTGAACCGAG GGCAGGATGAAGATGGTGAGGAAGAAGAGGAGAGGGGAGAGGCCACCGTCCAGGTCTCTTGCCTCTATAGACCACAGATGACTCAAGCCA TGCCAGAACCAAGCAGCCCATGCCTGGCTGTGGCGATTCAGAAGCAACGAGGGGAGCTATCCAGAGGGTCAGTGCTGAAGGTCTGGGCAG AAGACCTGCGAGACCCAGATGACTTGGACTTCAGCAACCTGGCTTTTGATGCCCGGATTGCAAGAATAAATGCCCTAAAGGAGAGCACAT ATGCAATGCCTGATGGGTTCCTTGCAGCCCAAAATGATGCCAATGAGCTGCTCTGTCTCGTCAGGGCAACCAAGGAGAAGAGGGAGGAGT CACGCCCTGAAGCGTACGACCTTACACTTTCTCAGTACAAGCAACTGTTATCCATTGAGTCCAGACAGTTGGGAAGTGCCTGTAGGAAAA TGGCGATGGCTGAGAAAAGCCCGGAGGAGATGCTCCTAGCTATGACTTCCAGCTTTCAAGTGCTCTGTTGCCTAACAGAAGCTTGCATGC GATTAGTTAAAGTCGTGAACTCAGAAACACAGCGGCAGGAAATTGTAGGGAAGATCGATGAAGTGGTCATAAATTACATTTGTCTACTGA AAGCTGCCGAAGCAGCCACTGGAAAGAACCCTGGGGACCCTAATGTTGGACTCTCGGCGCGACACTCAACCACCATGGCCGCTCTCGTAA GCACACTGACACGTTCTCTCAAGAGGCTTTTAAACAAATAAATATGGAAGTCACGTCATAATCTACCTTTGCAAAGCCATACATGAACTT TTATTTACTTTGTGTGTATGATGAACAGATGTCTCCTTTCTTCTCTCTGTATATTTTGTTATTTTATATAAAATAGGAGATAAAAGTCAC ATTGATGAAATGTTGAAATGTACTAATCAGATGTATTCTGTTTATATTATACATATATATACACGTAAAAGAAATATCCAAGAAAGTGAT GACATTTGGCTATTTTTCATATAGTTAAAACTCCAGGTATATGATGTGAAATTTTAAATTCTACCATGTTAGAGCAAAACAATGAATCCT ATCCCCTTTCTTTCCAAGTAGCTACTTGGAAACCATATCATTCATATTTAGAAGTAAAACACAAAACAAAAAAGAGAGAGAAAAGAAAAG AAATCACAATGTATATAAAACAGTACTTATGTTTTAAAATTATGATTTTTAAGCATTGGAAATAGCAAAAAGACATTTAAAATTCAAGAA GCTATTATGAATTACTAGAGAATATATCTGTAATAAATTAATTTTTTGCTCATAGTATTTGGTTACTGGATGCTTTCTTCCAAGAATCCC ACATATTTAATTTGGGTTTTTGCTACTGGGGCTACAAATTGGTGGGGATGGATTCTACTGTGTCAGCACAAATGCTCTTCACAGTGGTTC TAGCATTTAAAAAACTTCCCGGGGAGAAGAACAGAGGGGATGATGGGCAGTTTCCTAGGTAACACCTAGAGTTATAGAATATCTCATTAC ATAAAATGTATGGAATTAATAATACCAAAATTAATTATTTGATGGAAAGATCTGCTTTGACTAAATGTCAAAAATCTGCAAACCAAAGAC ATTATCTTCCCCTCATCCCAACTCAACTACGAAACTTAAAATTCCCTTTAGAGTGATAGGACATTTAGTAAAGTATTTGCAAACTTAAAA AAAGGAACATTTAATGATCATCAAAATTAAGTACAGATTCAGTAATGTAGACCAGACCACACACCAGCACCTGTGAGTCTCATCTCAGAT CACAGCTCTCAGCATAGGGCTTCATGCATCACCGCCTCTACAGAGGCTAAGGCTGCCAGTCAAATTTGGAATTATAGCGTAGTACTGGGA CAAAATCTCAAATCTTGGATGTTCCAGAAAATCAGGGAGAGATGGCTACTGTAATCATGGGAGCCATGAGTAAATAGTTAAGTATTTATT AAATAAATACTTAATCTGGATTGGCTGATAAAAATATGAAATCTGAAAAAAAAAAGAAAGAAATGGAAGTGGTATATTTGACCAGTTCAA GTGAAACCAATGGAATGCAAAGAACTTTCCAGGACTGTCACATCTCTAAAAGTACCCTGCAGTCATAAAATAAAATCGATATGTATATAT GTATTTCCTGGGTCATTCAGTGCTCAAGTTACATGCACTCCTACTTAGACAGGTGGCTCCTTAAGAACATGATGGGAGTACACCAGGTGC AAATATTTCTACTTTTGTAGCCTGCTGAGAAGGAGTCATAACACAGTCCACAATTGCAATCTCTCTCTAGTCAGCCATTCCACAGGGACT CAACAACAAAAGCCGCACGTGGTTATGGATGGCAGCAAAGGAAAGGAGTTTAGGTGTGTGTTATTATAAATAATGTTTAACTAAATAATA AAACATTATTTCATTACAATTATAATTATAAATATTGGTGTTTTGATATTGAGAGATATTAGTGGTGTTTACTGTGGAAAATCTTAGTAA ATATCATTCTGTGTACTAAAATCCTAACCTATTAATAGGATGTGTGCCCTATGTCAGACAGTGTGCTAAGCATATTAACTATATTATCTC ATTTAATCATCACAACAATCTGCTGGTTTGGACACTATTCTCTCTGGAGGCAATATGGATGAGTTCTTACGGATATGGGGTTTGGGGTCA GAAACATCTTGATTAAAATTTTGACTCTGCCATTTTCTAGCCCTTTTATGTTGGGAAAGCTACTTTTTCTAGTCTCAATTTCCTCATAAT AAAATGAAAATCAATTATAAGATCGATTTCCATAGGGTTGTCATGAGTTTTGAGTAAAAATGTGTATGTAAAGTTCTTACCACAATACCT GGCAGAGAGTAAGTATTCAATTAATGTTAGCTATTATTATCATCATAATCGTTGTGTTAAATATATTGCCCAAGATAATATGTGGGGGAA TGTTTGTTTTATATGCATATTGTATCCTGACTGTGTGCAGAACACATTATGTGTATTGCATATATGTAAAAGAAGTGTACAAGGAAGTGG CCATCCTTGTTCAAGTTACGTATCTAGTTAGAACAACTTCCCAGTCCATTGGAGTTCTTTGAGAAGCCTCAGGGAAGTAGCTCTGGGTCC TTCTAATCAACCTCCCATTACTGCGCCAGTAAGTTTCTGTTTCTTATAAATAAACTCTTTGCTATTCAGAAAACCTCAAGGGGCCCCCAC ATTCACTAAGCATGGGGCTCCTAACTGGGGTCCAGGTCCATAGAGTGTAGGAAGAACATATTAGAACAATACTTGTGCTTATTTTTATCT AGCTTTTTTATGTTTGTGTATGTTTTATAATGGCATAATAGTACAATGGTACATGTACATAATTTTAAATAAATAAATGAATGAATGAAT >81760_81760_3_SHROOM2-FRMPD4_SHROOM2_chrX_9912953_ENST00000380913_FRMPD4_chrX_12724945_ENST00000380682_length(amino acids)=2467AA_BP=1544 MPGVHGRGPGTLSGRAMEGAEPRARPERLAEAETRAADGGRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEI VGINDIGLSGFRQEAICLVKGSHKTLKLVVKRRSELGWRPHSWHATKFSDSHPELAASPFTSTSGCPSWSGRHHASSSSHDLSSSWEQTN LQRTLDHFSSLGSVDSLDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSSTPDHTLSKADTSSAENILYTVGLWEAPRQGGRQAQA AGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAA AAQHFTALAQAQPRGDRRPELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVRFPQSPHSGRHPPLYSD HSPLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPCVQGDLQAAQLWAGCWPSDTALGALESLPPPTVGQSPRHHLPQPE GPPDARETGRCYPLDKGAEGCSAGAQEPPRASRAEKASQRLAASITWADGESSRICPQETPLLHSLTQEGKRRPESSPEDSATRPPPFDA HVGKPTRRSDRFATTLRNEIQMHRAKLQKSRSTVALTAAGEAEDGTGRWRAGLGGGTQEGPLAGTYKDHLKEAQARVLRATSFKRRDLDP NPGDLYPESLEHRMGDPDTVPHFWEAGLAQPPSSTSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSPHQHPRTSEDTVGTF ADRWKFFEETSKPVPQRPAQKQALHGIPRDKPERPRTAGRTCEGTEPWSRTTSLGDSLNAHSAAEKAGTSDLPRRLGTFAEYQASWKEQR KPLEARSSGRCHSADDILDVSLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQSTPRQADAQCREGS PGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQR PPPPKREPRRYRATDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALLPP KQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEK DQIKTLSTSEQFYSRFCLYTRQGAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELAREIVGKDKSLADIL DPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLLPKIPSPRSTEERKEEPSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEED SGSDLDHDLSVKKQELIESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEFDKFRMFIGDLDKVVNLLLSLSGRLARVEN ALNNLDDGASPGDRLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFSE EESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNTATQETGPENKGKHNLLGPDWNCIPQMTTFIGEGE QEAQITYIDSKQKTVEITDSTMCPKEHRHLYIDNAYSSDGLNQQLSQPGEAPCEADYRSLAQRSLLTLSGPETLKKAQESPRGAKVSFIF GDFALDDGISPPTLGYETLLDEGPEMLEKQRNLYIGSANDMKGLDLTPEAEGIQFVENSVYANIGDVKSFQAAEGIEEPLLHDICYAENT DDAEDEDEVSCEEDLVVGEMNQPAILNLSGSSDDIIDLTSLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDSQSQAASFPEDKE KGSSLQNDEIPVSLIDAVPTSAEGKCEKGLDNAVVSTLGALEALSVSEEQQTSDNSGVAILRAYSPESSSDSGNETNSSEMTESSELATA QKQSENLSRMFLATHEGYHPLAEEQTEFPASKTPAGGLPPKSSHALAARPATDLPPKVVPSKQLLHSDHMEMEPETMETKSVTDYFSKLH MGSVAYSCTSKRKSKLADGEGKAPPNGNTTGKKQQGTKTAEMEEEASGKFGTVSSRDSQHLSTFNLERTAFRKDSQRWYVATEGGMAEKS GLEAATGKTFPRASGLGAREAEGKEEGAPDGETSDGSGLGQGDRFLTDVTCASSAKDLDNPEDADSSTCDHPSKLPEADESVARLCDYHL AKRMSSLQSEGHFSLQSSQGSSVDAGCGTGSSGSACATPVESPLCPSLGKHLIPDASGKGVNYIPSEERAPGLPNHGATFKELHPQTEGM -------------------------------------------------------------- >81760_81760_4_SHROOM2-FRMPD4_SHROOM2_chrX_9912953_ENST00000418909_FRMPD4_chrX_12724945_ENST00000380682_length(transcript)=8671nt_BP=1909nt AAATGCAAGCGGAGCCTTGAGCCGTGGAGGTGAAGGTTGACGGAGCCTGCGTGAGCTTGCCCATCAACAAGACAGCAGGCACAGACAGGC CAGCTGTTGTGAGCTTGGCTTTAGGACTCCATTCAGTAGGCAGGAGGAGAGCTGCAGCAGAGGCGGGCTGTGGGTCCCTGAAGCACATCG CTGCCTTCACAGCTGGGCGAACTCCCATCCAGCACGACAAGCAGATGCCCAGTGTCGGGAAGGCAGCCCAGGATCACAGCAGCACCCACC GAGTCAGAAGGCACCGAACCCACCCACATTCTCTGAACTATCTCACTGCCGGGGAGCCCCAGAGCTGCCCCGGGAGGGCCGGGGCCGAGC GGGAACCCTACCTCGAGATTATAGATACTCGGAGGAGAGCACCCCAGCAGACTTGGGACCCCGAGCCCAGAGCCCTGGCTCACCCCTGCA TGCTCGAGGACAAGACTCGTGGCCAGTGAGCTCAGCCCTGCTCTCCAAGAGGCCAGCCCCACAGAGGCCACCGCCACCCAAGCGCGAGCC CAGGAGATACAGGGCCACAGACGGCGCACCTGCTGACGCCCCCGTGGGCGTCCTCGGCAGGCCCTTCCCAACGCCATCCCCTGCGTCCCT GGATGTGTATGTGGCCCGCCTGTCCCTCTCCCACAGCCCCTCTGTGTTCAGCAGTGCCCAGCCCCAGGACACCCCGAAGGCCACTGTCTG TGAGCGTGGAAGCCAGCATGTGAGCGGGGACGCATCACGTCCTCTGCCAGAAGCACTGCTCCCTCCCAAGCAGCAGCACCTGCGCCTGCA GACGGCCACCATGGAGACCTCGCGCTCCCCCTCGCCCCAGTTCGCCCCCCAGAAACTGACGGACAAACCTCCCCTGCTCATCCAGGATGA GGATTCAACCAGAATTGAGCGGGTGATGGACAACAACACCACGGTGAAGATGGTGCCCATCAAGATCGTGCACTCGGAGAGCCAGCCAGA GAAGGAGAGCCGCCAGAGCCTGGCATGCCCCGCCGAGCCACCTGCCCTGCCCCACGGGCTGGAGAAAGACCAGATCAAGACGCTGAGCAC ATCTGAGCAGTTCTACTCGCGCTTCTGTCTGTACACGCGGCAGGGTGCTGAGCCCGAGGCCCCACATAGGGCCCAGCCGGCTGAGCCCCA GCCCCTGGGCACCCAGGTGCCCCCCGAGAAAGACCGCTGCACCTCCCCTCCAGGGCTCAGCTACATGAAGGCCAAAGAGAAGACTGTGGA AGACCTGAAGTCGGAGGAGCTGGCCAGGGAGATCGTGGGGAAGGATAAGTCCCTGGCCGACATCCTGGATCCCAGTGTGAAGATCAAAAC CACTATGGACTTGATGGAAGGCATCTTCCCCAAAGACGAGCACCTCCTGGAAGAAGCCCAGCAACGGAGGAAGCTGCTCCCCAAAATCCC CTCTCCTAGAAGCACAGAGGAGAGGAAAGAGGAGCCCAGCGTGCCTGCGGCCGTGTCCCTGGCCACCAATTCTACCTACTACAGCACGTC GGCCCCCAAGGCGGAGCTGCTGATCAAGATGAAGGACCTGCAGGAGCAGCAGGAGCACGAAGAGGATTCGGGAAGCGACTTGGACCACGA CCTGTCGGTGAAGAAGCAGGAGCTCATCGAGAGCATCAGCCGCAAGCTGCAGGTGCTCCGGGAGGCCCGCGAGAGCCTGCTGGAGGACGT GCAGGCCAACACCGTGCTGGGGGCCGAGGTGGAGGCCATCGTGAAAGGCGTCTGCAAGCCCAGCGAGTTTGACAAGTTCCGGATGTTCAT TGGAGACCTGGACAAAGTGGTGAACCTCCTGCTGTCGCTGTCAGGCCGCCTGGCCCGGGTGGAGAATGCCCTCAATAATTTGGACGACGG CGCTTCTCCCGGTGATCGGCTCTCTGCACTACAAGCCAAGGTCCATTATCTCAAGTTCCTCAGTGACCTACGATTGTATGGGGGCCGTGT GTTCAAGGCAACATTAGTGCAGGCAGAAAAGCGCTCGGAAGTGACTCTCCTGGTTGGGCCCCGGTATGGCATAAGCCATGTCATCAACAC CAAAACCAATCTGGTGGCTCTTTTAGCCGACTTTAGCCACGTCAACAGGATCGAAATGTTTTCCGAGGAGGAGAGCTTGGTGCGGGTAGA ACTCCACGTGCTAGATGTGAAGCCTATCACGCTTCTGATGGAATCCTCAGATGCCATGAACCTGGCCTGCTTGACGGCTGGATACTACCG GCTGCTTGTTGATTCCAGGAGGTCGATATTTAACATGGCCAACAAGAAAAACACAGCGACCCAGGAAACAGGACCTGAAAACAAGGGGAA GCATAACCTCCTTGGCCCAGATTGGAACTGTATACCCCAAATGACCACCTTTATTGGCGAAGGGGAACAAGAAGCCCAGATAACATACAT AGATTCAAAGCAGAAGACGGTGGAGATCACAGACAGCACCATGTGTCCAAAAGAGCACCGGCACTTGTACATAGACAATGCCTATAGTTC AGATGGACTTAACCAGCAGCTGAGCCAGCCCGGGGAGGCCCCCTGTGAGGCAGACTACAGAAGTCTAGCTCAGCGGTCCCTATTGACCCT CTCAGGACCAGAAACTCTGAAGAAAGCACAGGAATCTCCGAGAGGAGCTAAAGTGTCCTTTATTTTTGGAGACTTCGCCTTGGATGATGG TATTAGTCCCCCAACCCTTGGCTATGAAACGCTACTAGATGAGGGTCCTGAAATGCTGGAGAAGCAGAGAAATCTCTACATTGGCAGTGC CAATGACATGAAGGGCCTGGATCTCACTCCAGAGGCAGAGGGCATCCAGTTTGTGGAAAATTCTGTTTATGCAAACATAGGCGATGTGAA GAGCTTCCAGGCCGCGGAGGGGATCGAGGAACCCCTCTTGCATGACATCTGTTATGCAGAAAACACTGATGACGCGGAGGACGAGGACGA GGTGAGCTGCGAGGAGGACCTCGTGGTGGGGGAGATGAACCAGCCGGCCATCCTCAACCTGTCTGGGTCAAGCGATGACATCATTGACCT CACATCCCTGCCCCCTCCAGAAGGTGATGACAATGAGGATGACTTCCTGTTGCGTTCCTTGAACATGGCCATTGCCGCACCCCCACCTGG CTTTAGAGACAGTTCAGATGAAGAGGACTCTCAGAGCCAGGCAGCTTCCTTCCCCGAGGACAAGGAGAAAGGCAGCAGCCTGCAAAATGA TGAGATCCCCGTGTCCCTCATTGACGCTGTGCCCACCAGCGCCGAAGGCAAGTGTGAGAAGGGACTGGATAATGCCGTCGTCTCCACGCT GGGAGCTCTAGAGGCTCTATCCGTGTCAGAAGAACAGCAGACCAGTGACAATTCAGGTGTAGCCATCTTGCGGGCTTATAGTCCTGAGTC TTCGTCAGACTCGGGCAATGAAACTAACTCTTCTGAAATGACTGAGAGTTCTGAACTGGCCACAGCACAAAAACAGTCAGAAAACCTCTC CCGCATGTTCTTGGCCACTCACGAAGGCTACCACCCCCTTGCAGAAGAGCAGACCGAGTTCCCGGCCTCCAAGACCCCCGCTGGGGGCTT GCCTCCAAAGTCCTCGCACGCCCTGGCTGCTAGGCCAGCAACCGACCTCCCGCCCAAAGTTGTGCCTTCCAAGCAGTTACTTCACTCAGA CCACATGGAGATGGAGCCTGAAACTATGGAGACTAAGTCGGTCACTGACTATTTTAGCAAACTGCACATGGGGTCGGTGGCATACTCCTG CACTAGCAAAAGGAAAAGCAAGCTGGCCGATGGTGAGGGGAAGGCACCCCCTAATGGGAACACAACAGGAAAAAAACAGCAGGGGACCAA AACGGCAGAGATGGAGGAGGAGGCCAGTGGTAAATTTGGTACTGTGTCTTCACGAGACAGTCAACACCTGAGCACTTTTAATCTGGAGAG AACTGCCTTTCGCAAGGACAGTCAAAGATGGTATGTGGCCACTGAAGGTGGGATGGCTGAAAAAAGTGGATTAGAAGCAGCAACAGGGAA AACCTTTCCAAGAGCTTCTGGTCTTGGGGCAAGGGAGGCCGAAGGGAAGGAAGAAGGAGCTCCTGATGGAGAAACCAGTGATGGCTCAGG ACTTGGTCAAGGGGACCGCTTCTTAACTGACGTGACCTGTGCATCTTCAGCCAAAGACTTAGATAACCCAGAGGACGCTGACTCGTCCAC CTGCGACCATCCTTCCAAGCTTCCTGAGGCTGATGAGAGTGTGGCCCGCCTTTGTGACTACCACTTGGCCAAGCGGATGTCATCACTGCA AAGCGAGGGCCATTTTTCTCTGCAGAGCTCCCAAGGCTCTTCAGTGGATGCAGGCTGTGGCACAGGCAGCAGTGGCAGTGCCTGTGCCAC ACCCGTGGAGTCGCCGCTCTGCCCCTCCCTGGGGAAGCACTTGATTCCTGACGCTTCTGGGAAAGGCGTGAATTACATTCCTTCAGAGGA GAGAGCCCCTGGGCTTCCCAACCACGGAGCCACCTTTAAGGAACTGCACCCACAGACAGAAGGGATGTGTCCACGGATGACAGTGCCTGC TCTGCACACAGCCATTAACACCGAACCCCTGTTTGGCACATTGAGAGATGGATGCCATCGGCTCCCCAAGATTAAGGAAACCACAGTGTA GCTTTGACAGAGCCTGGGAAGGAGAGACGAGGAGGCATGCCTTCAGCTTGGTCTCAACATCCTGAAGCTGATCCCATCCTGCTACCATCA AACATTCACTCGGAATCAAAGGTGCCAATTCCAAATCAAGACCCTAATGATTTCTCCCAAGCAAATCAGGCATACGGAGAGGCTGTGAGC TGGCGGCCACCGGATCTGAGAGGGGGGAGCCTCAGGACACCTCCCAGCCAGAAGGCTCTGAGACATAGCAGCAGTATCCTCTCCGGATCT GTCGATTTGGAGACCTTCCGAGAGAGAACCAAGGGTGCAGTCAGCTTAAAGTGTCCAGGCATCACAGAAGCACAGGAGGCCAGTTCTGAA AGGCGAGCAGAACTCCCCCTGGGGAGGAAGCTCACCAAAAGTTTTTCCCAAAGCTCAATGCACTTGAGCTCTGAGGGGAGGTTTCACAAA AGGTCCCCAGTGGCTCATAAAGACTCAAAGCTGTATAGGACATTACCCTTGCGGAAGCTGGAGGGCAGCAATTGGAGATGCCGGGGACCC TTCAGCTATTGCTTCCTGAACCGAGGGCAGGATGAAGATGGTGAGGAAGAAGAGGAGAGGGGAGAGGCCACCGTCCAGGTCTCTTGCCTC TATAGACCACAGATGACTCAAGCCATGCCAGAACCAAGCAGCCCATGCCTGGCTGTGGCGATTCAGAAGCAACGAGGGGAGCTATCCAGA GGGTCAGTGCTGAAGGTCTGGGCAGAAGACCTGCGAGACCCAGATGACTTGGACTTCAGCAACCTGGCTTTTGATGCCCGGATTGCAAGA ATAAATGCCCTAAAGGAGAGCACATATGCAATGCCTGATGGGTTCCTTGCAGCCCAAAATGATGCCAATGAGCTGCTCTGTCTCGTCAGG GCAACCAAGGAGAAGAGGGAGGAGTCACGCCCTGAAGCGTACGACCTTACACTTTCTCAGTACAAGCAACTGTTATCCATTGAGTCCAGA CAGTTGGGAAGTGCCTGTAGGAAAATGGCGATGGCTGAGAAAAGCCCGGAGGAGATGCTCCTAGCTATGACTTCCAGCTTTCAAGTGCTC TGTTGCCTAACAGAAGCTTGCATGCGATTAGTTAAAGTCGTGAACTCAGAAACACAGCGGCAGGAAATTGTAGGGAAGATCGATGAAGTG GTCATAAATTACATTTGTCTACTGAAAGCTGCCGAAGCAGCCACTGGAAAGAACCCTGGGGACCCTAATGTTGGACTCTCGGCGCGACAC TCAACCACCATGGCCGCTCTCGTAAGCACACTGACACGTTCTCTCAAGAGGCTTTTAAACAAATAAATATGGAAGTCACGTCATAATCTA CCTTTGCAAAGCCATACATGAACTTTTATTTACTTTGTGTGTATGATGAACAGATGTCTCCTTTCTTCTCTCTGTATATTTTGTTATTTT ATATAAAATAGGAGATAAAAGTCACATTGATGAAATGTTGAAATGTACTAATCAGATGTATTCTGTTTATATTATACATATATATACACG TAAAAGAAATATCCAAGAAAGTGATGACATTTGGCTATTTTTCATATAGTTAAAACTCCAGGTATATGATGTGAAATTTTAAATTCTACC ATGTTAGAGCAAAACAATGAATCCTATCCCCTTTCTTTCCAAGTAGCTACTTGGAAACCATATCATTCATATTTAGAAGTAAAACACAAA ACAAAAAAGAGAGAGAAAAGAAAAGAAATCACAATGTATATAAAACAGTACTTATGTTTTAAAATTATGATTTTTAAGCATTGGAAATAG CAAAAAGACATTTAAAATTCAAGAAGCTATTATGAATTACTAGAGAATATATCTGTAATAAATTAATTTTTTGCTCATAGTATTTGGTTA CTGGATGCTTTCTTCCAAGAATCCCACATATTTAATTTGGGTTTTTGCTACTGGGGCTACAAATTGGTGGGGATGGATTCTACTGTGTCA GCACAAATGCTCTTCACAGTGGTTCTAGCATTTAAAAAACTTCCCGGGGAGAAGAACAGAGGGGATGATGGGCAGTTTCCTAGGTAACAC CTAGAGTTATAGAATATCTCATTACATAAAATGTATGGAATTAATAATACCAAAATTAATTATTTGATGGAAAGATCTGCTTTGACTAAA TGTCAAAAATCTGCAAACCAAAGACATTATCTTCCCCTCATCCCAACTCAACTACGAAACTTAAAATTCCCTTTAGAGTGATAGGACATT TAGTAAAGTATTTGCAAACTTAAAAAAAGGAACATTTAATGATCATCAAAATTAAGTACAGATTCAGTAATGTAGACCAGACCACACACC AGCACCTGTGAGTCTCATCTCAGATCACAGCTCTCAGCATAGGGCTTCATGCATCACCGCCTCTACAGAGGCTAAGGCTGCCAGTCAAAT TTGGAATTATAGCGTAGTACTGGGACAAAATCTCAAATCTTGGATGTTCCAGAAAATCAGGGAGAGATGGCTACTGTAATCATGGGAGCC ATGAGTAAATAGTTAAGTATTTATTAAATAAATACTTAATCTGGATTGGCTGATAAAAATATGAAATCTGAAAAAAAAAAGAAAGAAATG GAAGTGGTATATTTGACCAGTTCAAGTGAAACCAATGGAATGCAAAGAACTTTCCAGGACTGTCACATCTCTAAAAGTACCCTGCAGTCA TAAAATAAAATCGATATGTATATATGTATTTCCTGGGTCATTCAGTGCTCAAGTTACATGCACTCCTACTTAGACAGGTGGCTCCTTAAG AACATGATGGGAGTACACCAGGTGCAAATATTTCTACTTTTGTAGCCTGCTGAGAAGGAGTCATAACACAGTCCACAATTGCAATCTCTC TCTAGTCAGCCATTCCACAGGGACTCAACAACAAAAGCCGCACGTGGTTATGGATGGCAGCAAAGGAAAGGAGTTTAGGTGTGTGTTATT ATAAATAATGTTTAACTAAATAATAAAACATTATTTCATTACAATTATAATTATAAATATTGGTGTTTTGATATTGAGAGATATTAGTGG TGTTTACTGTGGAAAATCTTAGTAAATATCATTCTGTGTACTAAAATCCTAACCTATTAATAGGATGTGTGCCCTATGTCAGACAGTGTG CTAAGCATATTAACTATATTATCTCATTTAATCATCACAACAATCTGCTGGTTTGGACACTATTCTCTCTGGAGGCAATATGGATGAGTT CTTACGGATATGGGGTTTGGGGTCAGAAACATCTTGATTAAAATTTTGACTCTGCCATTTTCTAGCCCTTTTATGTTGGGAAAGCTACTT TTTCTAGTCTCAATTTCCTCATAATAAAATGAAAATCAATTATAAGATCGATTTCCATAGGGTTGTCATGAGTTTTGAGTAAAAATGTGT ATGTAAAGTTCTTACCACAATACCTGGCAGAGAGTAAGTATTCAATTAATGTTAGCTATTATTATCATCATAATCGTTGTGTTAAATATA TTGCCCAAGATAATATGTGGGGGAATGTTTGTTTTATATGCATATTGTATCCTGACTGTGTGCAGAACACATTATGTGTATTGCATATAT GTAAAAGAAGTGTACAAGGAAGTGGCCATCCTTGTTCAAGTTACGTATCTAGTTAGAACAACTTCCCAGTCCATTGGAGTTCTTTGAGAA GCCTCAGGGAAGTAGCTCTGGGTCCTTCTAATCAACCTCCCATTACTGCGCCAGTAAGTTTCTGTTTCTTATAAATAAACTCTTTGCTAT TCAGAAAACCTCAAGGGGCCCCCACATTCACTAAGCATGGGGCTCCTAACTGGGGTCCAGGTCCATAGAGTGTAGGAAGAACATATTAGA ACAATACTTGTGCTTATTTTTATCTAGCTTTTTTATGTTTGTGTATGTTTTATAATGGCATAATAGTACAATGGTACATGTACATAATTT >81760_81760_4_SHROOM2-FRMPD4_SHROOM2_chrX_9912953_ENST00000418909_FRMPD4_chrX_12724945_ENST00000380682_length(amino acids)=1544AA_BP=621 MRELAHQQDSRHRQASCCELGFRTPFSRQEESCSRGGLWVPEAHRCLHSWANSHPARQADAQCREGSPGSQQHPPSQKAPNPPTFSELSH CRGAPELPREGRGRAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDGAPADAPV GVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFA PQKLTDKPPLLIQDEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRFCLYTRQG AEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHL LEEAQQRRKLLPKIPSPRSTEERKEEPSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEEDSGSDLDHDLSVKKQELIESISRK LQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEFDKFRMFIGDLDKVVNLLLSLSGRLARVENALNNLDDGASPGDRLSALQAKVH YLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFSEEESLVRVELHVLDVKPITLLMES SDAMNLACLTAGYYRLLVDSRRSIFNMANKKNTATQETGPENKGKHNLLGPDWNCIPQMTTFIGEGEQEAQITYIDSKQKTVEITDSTMC PKEHRHLYIDNAYSSDGLNQQLSQPGEAPCEADYRSLAQRSLLTLSGPETLKKAQESPRGAKVSFIFGDFALDDGISPPTLGYETLLDEG PEMLEKQRNLYIGSANDMKGLDLTPEAEGIQFVENSVYANIGDVKSFQAAEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVGEMNQP AILNLSGSSDDIIDLTSLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDSQSQAASFPEDKEKGSSLQNDEIPVSLIDAVPTSAE GKCEKGLDNAVVSTLGALEALSVSEEQQTSDNSGVAILRAYSPESSSDSGNETNSSEMTESSELATAQKQSENLSRMFLATHEGYHPLAE EQTEFPASKTPAGGLPPKSSHALAARPATDLPPKVVPSKQLLHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLADGEGKA PPNGNTTGKKQQGTKTAEMEEEASGKFGTVSSRDSQHLSTFNLERTAFRKDSQRWYVATEGGMAEKSGLEAATGKTFPRASGLGAREAEG KEEGAPDGETSDGSGLGQGDRFLTDVTCASSAKDLDNPEDADSSTCDHPSKLPEADESVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSV DAGCGTGSSGSACATPVESPLCPSLGKHLIPDASGKGVNYIPSEERAPGLPNHGATFKELHPQTEGMCPRMTVPALHTAINTEPLFGTLR -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SHROOM2-FRMPD4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SHROOM2-FRMPD4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SHROOM2-FRMPD4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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