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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SHROOM4-ARID3A (FusionGDB2 ID:81796)

Fusion Gene Summary for SHROOM4-ARID3A

check button Fusion gene summary
Fusion gene informationFusion gene name: SHROOM4-ARID3A
Fusion gene ID: 81796
HgeneTgene
Gene symbol

SHROOM4

ARID3A

Gene ID

57477

1820

Gene nameshroom family member 4AT-rich interaction domain 3A
SynonymsSHAP|shrm4BRIGHT|DRIL1|DRIL3|E2FBP1
Cytomap

Xp11.22

19p13.3

Type of geneprotein-codingprotein-coding
Descriptionprotein Shroom4second homolog of apical proteinAT-rich interactive domain-containing protein 3AARID domain-containing 3AARID domain-containing protein 3AAT rich interactive domain 3A (BRIGHT- like) proteinAT rich interactive domain 3A (BRIGHT-like)B-cell regulator of IgH transcriptionE2F-binding
Modification date2020031320200313
UniProtAcc.

Q99856

Ensembl transtripts involved in fusion geneENST00000289292, ENST00000376020, 
ENST00000460112, ENST00000483955, 
ENST00000592216, ENST00000263620, 
Fusion gene scores* DoF score6 X 4 X 6=1448 X 9 X 5=360
# samples 710
** MAII scorelog2(7/144*10)=-1.04064198449735
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/360*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SHROOM4 [Title/Abstract] AND ARID3A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSHROOM4(50556902)-ARID3A(960092), # samples:4
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSHROOM4

GO:0000902

cell morphogenesis

16684770

HgeneSHROOM4

GO:0007420

brain development

16249884

HgeneSHROOM4

GO:0050890

cognition

16249884


check buttonFusion gene breakpoints across SHROOM4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARID3A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCECTCGA-BK-A0CC-01ASHROOM4chrX

50556902

-ARID3Achr19

960092

+
ChimerDB4UCECTCGA-BK-A0CC-01BSHROOM4chrX

50556902

-ARID3Achr19

960092

+
ChimerDB4UCECTCGA-BK-A0CCSHROOM4chrX

50556901

-ARID3Achr19

960091

+


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Fusion Gene ORF analysis for SHROOM4-ARID3A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000289292ENST00000592216SHROOM4chrX

50556902

-ARID3Achr19

960092

+
5CDS-intronENST00000289292ENST00000592216SHROOM4chrX

50556901

-ARID3Achr19

960091

+
5CDS-intronENST00000376020ENST00000592216SHROOM4chrX

50556902

-ARID3Achr19

960092

+
5CDS-intronENST00000376020ENST00000592216SHROOM4chrX

50556901

-ARID3Achr19

960091

+
In-frameENST00000289292ENST00000263620SHROOM4chrX

50556902

-ARID3Achr19

960092

+
In-frameENST00000289292ENST00000263620SHROOM4chrX

50556901

-ARID3Achr19

960091

+
In-frameENST00000376020ENST00000263620SHROOM4chrX

50556902

-ARID3Achr19

960092

+
In-frameENST00000376020ENST00000263620SHROOM4chrX

50556901

-ARID3Achr19

960091

+
intron-3CDSENST00000460112ENST00000263620SHROOM4chrX

50556902

-ARID3Achr19

960092

+
intron-3CDSENST00000460112ENST00000263620SHROOM4chrX

50556901

-ARID3Achr19

960091

+
intron-3CDSENST00000483955ENST00000263620SHROOM4chrX

50556902

-ARID3Achr19

960092

+
intron-3CDSENST00000483955ENST00000263620SHROOM4chrX

50556901

-ARID3Achr19

960091

+
intron-intronENST00000460112ENST00000592216SHROOM4chrX

50556902

-ARID3Achr19

960092

+
intron-intronENST00000460112ENST00000592216SHROOM4chrX

50556901

-ARID3Achr19

960091

+
intron-intronENST00000483955ENST00000592216SHROOM4chrX

50556902

-ARID3Achr19

960092

+
intron-intronENST00000483955ENST00000592216SHROOM4chrX

50556901

-ARID3Achr19

960091

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000376020SHROOM4chrX50556902-ENST00000263620ARID3Achr19960092+5106143261231401
ENST00000289292SHROOM4chrX50556902-ENST00000263620ARID3Achr19960092+53644012841489401
ENST00000376020SHROOM4chrX50556901-ENST00000263620ARID3Achr19960091+5106143261231401
ENST00000289292SHROOM4chrX50556901-ENST00000263620ARID3Achr19960091+53644012841489401

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000376020ENST00000263620SHROOM4chrX50556902-ARID3Achr19960092+0.0024555230.99754447
ENST00000289292ENST00000263620SHROOM4chrX50556902-ARID3Achr19960092+0.0026123330.9973877
ENST00000376020ENST00000263620SHROOM4chrX50556901-ARID3Achr19960091+0.0024555230.99754447
ENST00000289292ENST00000263620SHROOM4chrX50556901-ARID3Achr19960091+0.0026123330.9973877

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Fusion Genomic Features for SHROOM4-ARID3A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SHROOM4chrX50556901-ARID3Achr19960091+1.26E-050.9999875
SHROOM4chrX50556901-ARID3Achr19960091+1.26E-050.9999875
SHROOM4chrX50556901-ARID3Achr19960091+1.26E-050.9999875
SHROOM4chrX50556901-ARID3Achr19960091+1.26E-050.9999875
SHROOM4chrX50556901-ARID3Achr19960091+1.26E-050.9999875
SHROOM4chrX50556901-ARID3Achr19960091+1.26E-050.9999875

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SHROOM4-ARID3A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:50556902/chr19:960092)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ARID3A

Q99856

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. {ECO:0000269|PubMed:11812999, ECO:0000269|PubMed:12692263}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARID3AchrX:50556901chr19:960091ENST0000026362029424_445231594.0Compositional biasNote=Ala-rich
TgeneARID3AchrX:50556901chr19:960091ENST0000026362029550_579231594.0Compositional biasNote=Gly-rich
TgeneARID3AchrX:50556902chr19:960092ENST0000026362029424_445231594.0Compositional biasNote=Ala-rich
TgeneARID3AchrX:50556902chr19:960092ENST0000026362029550_579231594.0Compositional biasNote=Gly-rich
TgeneARID3AchrX:50556901chr19:960091ENST0000026362029238_330231594.0DomainARID
TgeneARID3AchrX:50556901chr19:960091ENST0000026362029444_541231594.0DomainREKLES
TgeneARID3AchrX:50556902chr19:960092ENST0000026362029238_330231594.0DomainARID
TgeneARID3AchrX:50556902chr19:960092ENST0000026362029444_541231594.0DomainREKLES
TgeneARID3AchrX:50556901chr19:960091ENST0000026362029445_488231594.0RegionImportant for nuclear localization
TgeneARID3AchrX:50556901chr19:960091ENST0000026362029490_513231594.0RegionNote=Homodimerization
TgeneARID3AchrX:50556901chr19:960091ENST0000026362029537_557231594.0RegionImportant for cytoplasmic localization
TgeneARID3AchrX:50556902chr19:960092ENST0000026362029445_488231594.0RegionImportant for nuclear localization
TgeneARID3AchrX:50556902chr19:960092ENST0000026362029490_513231594.0RegionNote=Homodimerization
TgeneARID3AchrX:50556902chr19:960092ENST0000026362029537_557231594.0RegionImportant for cytoplasmic localization

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSHROOM4chrX:50556901chr19:960091ENST00000289292-1101382_1488391898.0Coiled coilOntology_term=ECO:0000255
HgeneSHROOM4chrX:50556901chr19:960091ENST00000376020-191382_1488391494.0Coiled coilOntology_term=ECO:0000255
HgeneSHROOM4chrX:50556901chr19:960091ENST00000460112-181382_148801378.0Coiled coilOntology_term=ECO:0000255
HgeneSHROOM4chrX:50556902chr19:960092ENST00000289292-1101382_1488391898.0Coiled coilOntology_term=ECO:0000255
HgeneSHROOM4chrX:50556902chr19:960092ENST00000376020-191382_1488391494.0Coiled coilOntology_term=ECO:0000255
HgeneSHROOM4chrX:50556902chr19:960092ENST00000460112-181382_148801378.0Coiled coilOntology_term=ECO:0000255
HgeneSHROOM4chrX:50556901chr19:960091ENST00000289292-1101100_1107391898.0Compositional biasNote=Poly-Pro
HgeneSHROOM4chrX:50556901chr19:960091ENST00000289292-1101119_1135391898.0Compositional biasNote=Gln-rich
HgeneSHROOM4chrX:50556901chr19:960091ENST00000289292-1101136_1181391898.0Compositional biasNote=Glu-rich
HgeneSHROOM4chrX:50556901chr19:960091ENST00000289292-110871_937391898.0Compositional biasNote=Cys-rich
HgeneSHROOM4chrX:50556901chr19:960091ENST00000376020-191100_1107391494.0Compositional biasNote=Poly-Pro
HgeneSHROOM4chrX:50556901chr19:960091ENST00000376020-191119_1135391494.0Compositional biasNote=Gln-rich
HgeneSHROOM4chrX:50556901chr19:960091ENST00000376020-191136_1181391494.0Compositional biasNote=Glu-rich
HgeneSHROOM4chrX:50556901chr19:960091ENST00000376020-19871_937391494.0Compositional biasNote=Cys-rich
HgeneSHROOM4chrX:50556901chr19:960091ENST00000460112-181100_110701378.0Compositional biasNote=Poly-Pro
HgeneSHROOM4chrX:50556901chr19:960091ENST00000460112-181119_113501378.0Compositional biasNote=Gln-rich
HgeneSHROOM4chrX:50556901chr19:960091ENST00000460112-181136_118101378.0Compositional biasNote=Glu-rich
HgeneSHROOM4chrX:50556901chr19:960091ENST00000460112-18871_93701378.0Compositional biasNote=Cys-rich
HgeneSHROOM4chrX:50556902chr19:960092ENST00000289292-1101100_1107391898.0Compositional biasNote=Poly-Pro
HgeneSHROOM4chrX:50556902chr19:960092ENST00000289292-1101119_1135391898.0Compositional biasNote=Gln-rich
HgeneSHROOM4chrX:50556902chr19:960092ENST00000289292-1101136_1181391898.0Compositional biasNote=Glu-rich
HgeneSHROOM4chrX:50556902chr19:960092ENST00000289292-110871_937391898.0Compositional biasNote=Cys-rich
HgeneSHROOM4chrX:50556902chr19:960092ENST00000376020-191100_1107391494.0Compositional biasNote=Poly-Pro
HgeneSHROOM4chrX:50556902chr19:960092ENST00000376020-191119_1135391494.0Compositional biasNote=Gln-rich
HgeneSHROOM4chrX:50556902chr19:960092ENST00000376020-191136_1181391494.0Compositional biasNote=Glu-rich
HgeneSHROOM4chrX:50556902chr19:960092ENST00000376020-19871_937391494.0Compositional biasNote=Cys-rich
HgeneSHROOM4chrX:50556902chr19:960092ENST00000460112-181100_110701378.0Compositional biasNote=Poly-Pro
HgeneSHROOM4chrX:50556902chr19:960092ENST00000460112-181119_113501378.0Compositional biasNote=Gln-rich
HgeneSHROOM4chrX:50556902chr19:960092ENST00000460112-181136_118101378.0Compositional biasNote=Glu-rich
HgeneSHROOM4chrX:50556902chr19:960092ENST00000460112-18871_93701378.0Compositional biasNote=Cys-rich
HgeneSHROOM4chrX:50556901chr19:960091ENST00000289292-11010_92391898.0DomainPDZ
HgeneSHROOM4chrX:50556901chr19:960091ENST00000289292-1101213_1492391898.0DomainASD2
HgeneSHROOM4chrX:50556901chr19:960091ENST00000376020-1910_92391494.0DomainPDZ
HgeneSHROOM4chrX:50556901chr19:960091ENST00000376020-191213_1492391494.0DomainASD2
HgeneSHROOM4chrX:50556901chr19:960091ENST00000460112-1810_9201378.0DomainPDZ
HgeneSHROOM4chrX:50556901chr19:960091ENST00000460112-181213_149201378.0DomainASD2
HgeneSHROOM4chrX:50556902chr19:960092ENST00000289292-11010_92391898.0DomainPDZ
HgeneSHROOM4chrX:50556902chr19:960092ENST00000289292-1101213_1492391898.0DomainASD2
HgeneSHROOM4chrX:50556902chr19:960092ENST00000376020-1910_92391494.0DomainPDZ
HgeneSHROOM4chrX:50556902chr19:960092ENST00000376020-191213_1492391494.0DomainASD2
HgeneSHROOM4chrX:50556902chr19:960092ENST00000460112-1810_9201378.0DomainPDZ
HgeneSHROOM4chrX:50556902chr19:960092ENST00000460112-181213_149201378.0DomainASD2
TgeneARID3AchrX:50556901chr19:960091ENST000002636202967_70231594.0Compositional biasNote=Poly-Ala
TgeneARID3AchrX:50556901chr19:960091ENST000002636202989_157231594.0Compositional biasNote=Glu-rich
TgeneARID3AchrX:50556902chr19:960092ENST000002636202967_70231594.0Compositional biasNote=Poly-Ala
TgeneARID3AchrX:50556902chr19:960092ENST000002636202989_157231594.0Compositional biasNote=Glu-rich
TgeneARID3AchrX:50556901chr19:960091ENST0000026362029119_156231594.0RegionNote=Acidic
TgeneARID3AchrX:50556902chr19:960092ENST0000026362029119_156231594.0RegionNote=Acidic


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Fusion Gene Sequence for SHROOM4-ARID3A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>81796_81796_1_SHROOM4-ARID3A_SHROOM4_chrX_50556901_ENST00000289292_ARID3A_chr19_960091_ENST00000263620_length(transcript)=5364nt_BP=401nt
CCGTTTTCTTGTCCATTACGCGCTATCCCTCCGCCTCTCCTTCTTTCTTTTCTTTTCTTTTTTTCCCTTCTCCTTTTCCCCCCTCTCTCC
CCCTTTCTCCAGCTCCGTGTCATTTCCTCCTTGCGCTCGCTCGCTGCCTGAGCGTCTCCAGCCGGGAGAGTAGGCGGAGCAGGGCGGTGC
GGGGTGGCGTAGAGCTGGAGGGCGATGGTGGCGGAGCTGCTGGGGGCGGAGGCAACGTAGCCCCCTCGGAAAAGGAGCCCGGCGGCGCCT
GAGCCCAGCCGAGGATGGAGAACCGGCCTGGGTCCTTCCAGTACGTCCCTGTGCAGCTGCAAGGGGGGGCACCCTGGGGCTTCACCCTTA
AGGGGGGTCTGGAACACTGTGAGCCGCTCACAGTGTCTAAGCTCTACGAACTCGACGGGGACCCCAAGAGGAAGGAATTCCTGGATGACT
TGTTCAGCTTCATGCAGAAGCGAGGGACACCTGTGAACCGCATCCCCATCATGGCCAAACAGGTCCTTGACCTGTTCATGCTGTACGTGC
TGGTGACGGAGAAGGGCGGCCTCGTGGAGGTCATCAACAAGAAGCTGTGGCGTGAGATCACCAAGGGCCTCAACCTGCCCACGTCCATCA
CCAGTGCAGCCTTCACCCTGCGGACCCAATACATGAAGTACCTGTACCCCTACGAGTGTGAGAAGCGGGGCCTCAGTAACCCCAATGAGC
TCCAGGCAGCCATAGACAGCAACCGACGGGAGGGCCGGCGCCAGAGCTTTGGTGGCTCCCTCTTTGCCTACTCGCCAGGCGGGGCACACG
GCATGCTCTCCTCACCCAAGCTACCCGTGTCCTCCCTGGGCCTGGCCGCAAGCACCAATGGCAGCTCCATCACCCCCGCCCCTAAGATCA
AGAAAGAGGAGGACTCAGCCATCCCCATCACAGTCCCTGGCCGCCTGCCTGTGTCCCTGGCGGGCCACCCTGTGGTGGCAGCCCAGGCAG
CAGCTGTGCAAGCAGCAGCCGCCCAAGCAGCTGTGGCCGCACAGGCAGCTGCCCTGGAACAGCTGCGGGAGAAGCTGGAGTCTGCAGAGC
CTCCGGAGAAGAAGATGGCCCTGGTGGCCGATGAGCAGCAACGGCTGATGCAACGTGCACTCCAGCAGAACTTCCTGGCCATGGCGGCCC
AGCTGCCCATGAGCATTCGGATCAACAGCCAAGCCTCCGAAAGCCGCCAGGACTCTGCTGTGAACCTGACGGGCACCAACGGCAGCAACA
GCATCAGCATGTCGGTGGAGATCAACGGCATCATGTACACAGGAGTTCTGTTTGCTCAGCCGCCGGCCCCCACGCCAACCTCTGCTCCCA
ACAAAGGAGGCGGCGGCGGCGGCGGCAGCAGCAGCAACGCAGGCGGCCGGGGAGGAAACACCGGAACCAGCGGCGGCCAGGCTGGGCCAG
CGGGGCTGTCCACACCCTCCACATCTACCTCAAATAACTCGTTGCCTTAACCGCATCACTCCCCACCCGCCACCCACCCTGGAGCCCGCC
GGCCTGGGCAGGGGGTCCAGGTGGGCCACACAGGGGCCAGGATGGCGGAAGATACGGGTGGGGAGGGAAGATATCCAGAAAGGAGCCACA
GCTGACGCCAAAAAGAAAAGAAAAAAGATATATATATATATATATATATATACACGTATATATATAAAGAGAATTTAATAAAACAGGGGA
AAACCAAGGAACACTTGAATTTCTCAGGTTTTGGACATTCAGAGAGATGAATTGTGAGAACAGCAAAGAAATCCATCAGAAAAACAGAAA
GAGGCAGACGTTTCCCAGGGCGTTCAGGCAGCCCTGATGGACCGAAGGCTCTGGTGTCTGGTTTGGCCCCACAGCAGTGTGGGCCGATCC
TGTTTACCTCATACATCCCTGCACTGTGTGTTTTCATTTTTGTCTGCTTTAGTTCTCTTTTATTTTCTATTCACCACACACTCACCACTC
CCAGCTTCTCGTGTCCAGTGAAACCCCTGAACCAAGATCACTGAATTTTTGTTTTTTTCTTGTTGCTTTGGGAAATTTTTTTTTCTCTGT
AGGGTTTTTAAGAGGTTTCGGGGGTTTTGTTGTGTAAATATTCTATTTTATTCTTGGGGGGATCAAACCTTAGGAAAAGGATATCTATAT
ATCTATATAGCTATATATTTGTGTTCCTTCAGGGAAACTGGTCTTGAAAAAGCAAGAAAAAAAAGCAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAACTCACCTTTTTATTTTTCCCATGACCAATTTGGGTCCCTTTGTCCATTTCTGGGGGTGCGTTGGGCAGCTGTGAGCCCAGCACA
TCGGATCCCTGGGGCTAGAGCCGCGGAGCCAATGAACTCAGGTGCTATGGGCCGGGCTGGGGCAGAGGGTGCATGCTGGGGTCCCACCGG
CCAGGGGCCCCTGACAGTGAATTGCTGACTGTGATATTCCACGATGCTTTTGCTTGTGCCGTGCTTGTCTGCTGGGCTCTCGAGTCAGGG
GCCTGGAAATTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTTGCTCTTGTCGCCCAGGCTGGAGTGAGTGCAATGGTGCGATCTTGGCT
CACTGCAACCTGCACCTCCCAGGTGCAAGCGATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGATTACAGGCGCCCGCCACCACGCCCAG
TTAATTTTTGTATTTTTAGTAGAGATGGGGGTTTTGCCATGTTGGTCAGGCTGATCTCGAACTCCTGACCTCAGGTGATCTGCCCGCCTT
GGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCGCCACGCTGGCCCGGTCTGGAAATCTTATCTAAAAAGTAGCAAGTGCTGGAAAAA
GGGCCTGGGGGGCGGGGGTGGTTCTTGTCGAAGCCCCCAGGCTCCTGTCTCAGGGATGAATGTGGCGTCTCATTGGGATTCTTCTCTTGC
CCGAAAGGGCTGCTTTTGAGGACTATCAATACTGGGGAGTGGGGGTGAAGCCGGACCTCACTCAGGGTGAGGATTTCAGGGCCCCGGCAT
CCTGAACACCCCCCACACCCCAACATTCTCCTCGCTCTGTCCCTTCCTCTTCTCCCAACCCCTTTTGTGCTGGGGCTGCGAGCTCCCCGA
GTTCTGCGGTGACTAAATCGAGGCCGAGAAGGGAGGCTGCCCCCCACCACCCTGTGGGTCAGTACCCCTCCCCCTGGCTTGGAGAAAGTG
GGGTCACCGCAGCTGAGCTGGGGGGTTATTTTGGCTGGAGCTGCTGGAGCAGAAAGGCTGGGTCTGAAATGCCCAGCAGGGTCTGGGGAC
TTCGTTGGACCCGCGTGGTGTTGGGCGGGGCTGTCGTGTCCTACACGGGAGCTCTGGGCTTTCATTTCTCTTGGGGTGCAGTGGGGATTA
ACTCAGCTATTCCCAGGGTAAGCCTGGGTCTCTAATTGGGCCCTGGGAGCCCTGTTAGGCCACCGGCATGGGGGCTTGGTGAGGAAGGGG
ACTCCCCAGCTCCCCCCACTCCCAACCACCTCCCCATTGCCTTGGAGACCCCTGGGGAGGGGGCTGGGGGGCTTCTGAGCCCCTGAGTCT
AGGTTCACTTTCCCGTCGGGCTGTGGGAGGGGACTGTCACTTTCCTGTGTCTTTGGGGAGGGGACCCCCACTTCCTTCTCGGATCTCAGG
GCCGTGGACACACACCCCCTTTCCAGGAGGGGGTGGTGGGCGTCTAGGTTTTCCTTGTCCCTTCCTGGGGCCAGCACCGTAGCAGCACAA
TCACCCCGGGAAGGGGGTGTCTGTTTGCCTCCAGACACAATCGGGCCCCACTCGCAGAACCACCTGGACTCTGTCCGTGTCTGTCCCCCG
GCCTCCAGGGCTCCTCTCCCGGGACCCCCGTCCCACGCCTGGGCCCCGCGCCGGGGGAAGCGCCTGCTGCCTATCTCTGTCTACCTCAGG
TCTGACTTTTGATGCCAAAATCTGAGCCCCTGGGGTGCCTCTCCCCCGCCTCCCGTGCACCAGGGTCTGCAGCAGCCACTGGGGCCTGGC
TGCCTGCTGCATCTGGCGGCCCTGGACCCCTGGGGCCCCCGTGCACCTGCCCACCTCGGAGCCTGGGGAGGGGCCGTGCAGGGTCGAGGG
CTGGGTCGTCTCCCTCGGGCTGCGTGTGTGTGTCGGGAATCCTGCGTGTCGTGTCTGTGGGCGATCCGGCCTCCCGGCGGTGGGTGGACC
TGGATTCTAACTCAGAGGACTTGAGCCTGCTGTTAACTCCGATGATTGTAGGGACAGGCGGGGTGGGTGGGGGGTGGGCGCGAGGCTGGG
TCCCGGCCCAGGAGAAGGAAGTCGCTGAAGGCAGTGGCCATGCTGGCCGTGGAAATGGGAGGCGGTTGCAGAGGGTCTATGGGGCCCGGT
CCTGGATACTCGGCAGGAAGCCGTGTCTGCAGAGGCTCCTCCCTGCCTCAGGTGGCCCCGTTCAACCCCAGCCGTGCCCATCTCCTGCCA
CCGCCTGTCGGTGGGGGTTTAAATTCGGTGTGGCTTTCTGGGGTGCAGCTCAGCACCCCCCCTTATGCAGACTGGGAGGGGGTCGGGCAG
TCCCCTCAGCCACGAGGACCCTGGATGGGTTCTAGTTCACTTGGGACCGTGGGGCCTGGCTGCGTACTGAGTGGGTGCCCCACAGTCAAG
GCCAACGGGGGCTCCCCCTGCTCTGAGATGTTGGGAGAAAGGCGGCTTCTGGAACCTTCCGTGGGACCCGTAAGTGGCTGTCCAGAAAGG
CGGGAGGGTGGGCACGGGGCACGGGGGGCAGCTGGGGTCGTTGTTAAGGGTCACGCATCTGTACAGTTGAATTTCCTTTCTCTTATCATG
TTTTACCCACCTTGTCCCTTTTTTCCCCAATTGTGCTTTTGCATTTTTTTCCTTGGCAAATGTAAACTCAGCCTTTCATTCATGACGTGT
GAAATTTCAGTTTCTCTGGAGTTTGTCAGACGGCGTGGGAACCACGCCTGAAACTCAGGTAATAGGAGGAAAAAAAAAAAAACTTAAAAA
AATTTTTAAAAAACATAAAACTACTCTCTACCTCTGGCTGGGCCCAGCCTGTCTCGCCCTGGCCGCGGCAGGGTGGCCTGTAACAATTTC
AGTTTTCGCAGAACATTCAGGTATTAAAAGGAAAAAAAAAAAAAAAGACAAAAAGACCAAAAAAAAAAAAAAGTGTGATTTTGAAATTTA
AAAGAACACTGAAAGTTTACATTTTATAGTAACATTATTATGCAGATTGTATTTAAACTTCAGAAATATTTAAGACGATTGTAACCCTGT

>81796_81796_1_SHROOM4-ARID3A_SHROOM4_chrX_50556901_ENST00000289292_ARID3A_chr19_960091_ENST00000263620_length(amino acids)=401AA_BP=37
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEK
GGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAIDSNRREGRRQSFGGSLFAYSPGGAHGMLSS
PKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKK
MALVADEQQRLMQRALQQNFLAMAAQLPMSIRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGG

--------------------------------------------------------------
>81796_81796_2_SHROOM4-ARID3A_SHROOM4_chrX_50556901_ENST00000376020_ARID3A_chr19_960091_ENST00000263620_length(transcript)=5106nt_BP=143nt
CCGGCGGCGCCTGAGCCCAGCCGAGGATGGAGAACCGGCCTGGGTCCTTCCAGTACGTCCCTGTGCAGCTGCAAGGGGGGGCACCCTGGG
GCTTCACCCTTAAGGGGGGTCTGGAACACTGTGAGCCGCTCACAGTGTCTAAGCTCTACGAACTCGACGGGGACCCCAAGAGGAAGGAAT
TCCTGGATGACTTGTTCAGCTTCATGCAGAAGCGAGGGACACCTGTGAACCGCATCCCCATCATGGCCAAACAGGTCCTTGACCTGTTCA
TGCTGTACGTGCTGGTGACGGAGAAGGGCGGCCTCGTGGAGGTCATCAACAAGAAGCTGTGGCGTGAGATCACCAAGGGCCTCAACCTGC
CCACGTCCATCACCAGTGCAGCCTTCACCCTGCGGACCCAATACATGAAGTACCTGTACCCCTACGAGTGTGAGAAGCGGGGCCTCAGTA
ACCCCAATGAGCTCCAGGCAGCCATAGACAGCAACCGACGGGAGGGCCGGCGCCAGAGCTTTGGTGGCTCCCTCTTTGCCTACTCGCCAG
GCGGGGCACACGGCATGCTCTCCTCACCCAAGCTACCCGTGTCCTCCCTGGGCCTGGCCGCAAGCACCAATGGCAGCTCCATCACCCCCG
CCCCTAAGATCAAGAAAGAGGAGGACTCAGCCATCCCCATCACAGTCCCTGGCCGCCTGCCTGTGTCCCTGGCGGGCCACCCTGTGGTGG
CAGCCCAGGCAGCAGCTGTGCAAGCAGCAGCCGCCCAAGCAGCTGTGGCCGCACAGGCAGCTGCCCTGGAACAGCTGCGGGAGAAGCTGG
AGTCTGCAGAGCCTCCGGAGAAGAAGATGGCCCTGGTGGCCGATGAGCAGCAACGGCTGATGCAACGTGCACTCCAGCAGAACTTCCTGG
CCATGGCGGCCCAGCTGCCCATGAGCATTCGGATCAACAGCCAAGCCTCCGAAAGCCGCCAGGACTCTGCTGTGAACCTGACGGGCACCA
ACGGCAGCAACAGCATCAGCATGTCGGTGGAGATCAACGGCATCATGTACACAGGAGTTCTGTTTGCTCAGCCGCCGGCCCCCACGCCAA
CCTCTGCTCCCAACAAAGGAGGCGGCGGCGGCGGCGGCAGCAGCAGCAACGCAGGCGGCCGGGGAGGAAACACCGGAACCAGCGGCGGCC
AGGCTGGGCCAGCGGGGCTGTCCACACCCTCCACATCTACCTCAAATAACTCGTTGCCTTAACCGCATCACTCCCCACCCGCCACCCACC
CTGGAGCCCGCCGGCCTGGGCAGGGGGTCCAGGTGGGCCACACAGGGGCCAGGATGGCGGAAGATACGGGTGGGGAGGGAAGATATCCAG
AAAGGAGCCACAGCTGACGCCAAAAAGAAAAGAAAAAAGATATATATATATATATATATATATACACGTATATATATAAAGAGAATTTAA
TAAAACAGGGGAAAACCAAGGAACACTTGAATTTCTCAGGTTTTGGACATTCAGAGAGATGAATTGTGAGAACAGCAAAGAAATCCATCA
GAAAAACAGAAAGAGGCAGACGTTTCCCAGGGCGTTCAGGCAGCCCTGATGGACCGAAGGCTCTGGTGTCTGGTTTGGCCCCACAGCAGT
GTGGGCCGATCCTGTTTACCTCATACATCCCTGCACTGTGTGTTTTCATTTTTGTCTGCTTTAGTTCTCTTTTATTTTCTATTCACCACA
CACTCACCACTCCCAGCTTCTCGTGTCCAGTGAAACCCCTGAACCAAGATCACTGAATTTTTGTTTTTTTCTTGTTGCTTTGGGAAATTT
TTTTTTCTCTGTAGGGTTTTTAAGAGGTTTCGGGGGTTTTGTTGTGTAAATATTCTATTTTATTCTTGGGGGGATCAAACCTTAGGAAAA
GGATATCTATATATCTATATAGCTATATATTTGTGTTCCTTCAGGGAAACTGGTCTTGAAAAAGCAAGAAAAAAAAGCAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAACTCACCTTTTTATTTTTCCCATGACCAATTTGGGTCCCTTTGTCCATTTCTGGGGGTGCGTTGGGCAGCTGT
GAGCCCAGCACATCGGATCCCTGGGGCTAGAGCCGCGGAGCCAATGAACTCAGGTGCTATGGGCCGGGCTGGGGCAGAGGGTGCATGCTG
GGGTCCCACCGGCCAGGGGCCCCTGACAGTGAATTGCTGACTGTGATATTCCACGATGCTTTTGCTTGTGCCGTGCTTGTCTGCTGGGCT
CTCGAGTCAGGGGCCTGGAAATTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTTGCTCTTGTCGCCCAGGCTGGAGTGAGTGCAATGGT
GCGATCTTGGCTCACTGCAACCTGCACCTCCCAGGTGCAAGCGATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGATTACAGGCGCCCGC
CACCACGCCCAGTTAATTTTTGTATTTTTAGTAGAGATGGGGGTTTTGCCATGTTGGTCAGGCTGATCTCGAACTCCTGACCTCAGGTGA
TCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCGCCACGCTGGCCCGGTCTGGAAATCTTATCTAAAAAGTAGCAA
GTGCTGGAAAAAGGGCCTGGGGGGCGGGGGTGGTTCTTGTCGAAGCCCCCAGGCTCCTGTCTCAGGGATGAATGTGGCGTCTCATTGGGA
TTCTTCTCTTGCCCGAAAGGGCTGCTTTTGAGGACTATCAATACTGGGGAGTGGGGGTGAAGCCGGACCTCACTCAGGGTGAGGATTTCA
GGGCCCCGGCATCCTGAACACCCCCCACACCCCAACATTCTCCTCGCTCTGTCCCTTCCTCTTCTCCCAACCCCTTTTGTGCTGGGGCTG
CGAGCTCCCCGAGTTCTGCGGTGACTAAATCGAGGCCGAGAAGGGAGGCTGCCCCCCACCACCCTGTGGGTCAGTACCCCTCCCCCTGGC
TTGGAGAAAGTGGGGTCACCGCAGCTGAGCTGGGGGGTTATTTTGGCTGGAGCTGCTGGAGCAGAAAGGCTGGGTCTGAAATGCCCAGCA
GGGTCTGGGGACTTCGTTGGACCCGCGTGGTGTTGGGCGGGGCTGTCGTGTCCTACACGGGAGCTCTGGGCTTTCATTTCTCTTGGGGTG
CAGTGGGGATTAACTCAGCTATTCCCAGGGTAAGCCTGGGTCTCTAATTGGGCCCTGGGAGCCCTGTTAGGCCACCGGCATGGGGGCTTG
GTGAGGAAGGGGACTCCCCAGCTCCCCCCACTCCCAACCACCTCCCCATTGCCTTGGAGACCCCTGGGGAGGGGGCTGGGGGGCTTCTGA
GCCCCTGAGTCTAGGTTCACTTTCCCGTCGGGCTGTGGGAGGGGACTGTCACTTTCCTGTGTCTTTGGGGAGGGGACCCCCACTTCCTTC
TCGGATCTCAGGGCCGTGGACACACACCCCCTTTCCAGGAGGGGGTGGTGGGCGTCTAGGTTTTCCTTGTCCCTTCCTGGGGCCAGCACC
GTAGCAGCACAATCACCCCGGGAAGGGGGTGTCTGTTTGCCTCCAGACACAATCGGGCCCCACTCGCAGAACCACCTGGACTCTGTCCGT
GTCTGTCCCCCGGCCTCCAGGGCTCCTCTCCCGGGACCCCCGTCCCACGCCTGGGCCCCGCGCCGGGGGAAGCGCCTGCTGCCTATCTCT
GTCTACCTCAGGTCTGACTTTTGATGCCAAAATCTGAGCCCCTGGGGTGCCTCTCCCCCGCCTCCCGTGCACCAGGGTCTGCAGCAGCCA
CTGGGGCCTGGCTGCCTGCTGCATCTGGCGGCCCTGGACCCCTGGGGCCCCCGTGCACCTGCCCACCTCGGAGCCTGGGGAGGGGCCGTG
CAGGGTCGAGGGCTGGGTCGTCTCCCTCGGGCTGCGTGTGTGTGTCGGGAATCCTGCGTGTCGTGTCTGTGGGCGATCCGGCCTCCCGGC
GGTGGGTGGACCTGGATTCTAACTCAGAGGACTTGAGCCTGCTGTTAACTCCGATGATTGTAGGGACAGGCGGGGTGGGTGGGGGGTGGG
CGCGAGGCTGGGTCCCGGCCCAGGAGAAGGAAGTCGCTGAAGGCAGTGGCCATGCTGGCCGTGGAAATGGGAGGCGGTTGCAGAGGGTCT
ATGGGGCCCGGTCCTGGATACTCGGCAGGAAGCCGTGTCTGCAGAGGCTCCTCCCTGCCTCAGGTGGCCCCGTTCAACCCCAGCCGTGCC
CATCTCCTGCCACCGCCTGTCGGTGGGGGTTTAAATTCGGTGTGGCTTTCTGGGGTGCAGCTCAGCACCCCCCCTTATGCAGACTGGGAG
GGGGTCGGGCAGTCCCCTCAGCCACGAGGACCCTGGATGGGTTCTAGTTCACTTGGGACCGTGGGGCCTGGCTGCGTACTGAGTGGGTGC
CCCACAGTCAAGGCCAACGGGGGCTCCCCCTGCTCTGAGATGTTGGGAGAAAGGCGGCTTCTGGAACCTTCCGTGGGACCCGTAAGTGGC
TGTCCAGAAAGGCGGGAGGGTGGGCACGGGGCACGGGGGGCAGCTGGGGTCGTTGTTAAGGGTCACGCATCTGTACAGTTGAATTTCCTT
TCTCTTATCATGTTTTACCCACCTTGTCCCTTTTTTCCCCAATTGTGCTTTTGCATTTTTTTCCTTGGCAAATGTAAACTCAGCCTTTCA
TTCATGACGTGTGAAATTTCAGTTTCTCTGGAGTTTGTCAGACGGCGTGGGAACCACGCCTGAAACTCAGGTAATAGGAGGAAAAAAAAA
AAAACTTAAAAAAATTTTTAAAAAACATAAAACTACTCTCTACCTCTGGCTGGGCCCAGCCTGTCTCGCCCTGGCCGCGGCAGGGTGGCC
TGTAACAATTTCAGTTTTCGCAGAACATTCAGGTATTAAAAGGAAAAAAAAAAAAAAAGACAAAAAGACCAAAAAAAAAAAAAAGTGTGA
TTTTGAAATTTAAAAGAACACTGAAAGTTTACATTTTATAGTAACATTATTATGCAGATTGTATTTAAACTTCAGAAATATTTAAGACGA

>81796_81796_2_SHROOM4-ARID3A_SHROOM4_chrX_50556901_ENST00000376020_ARID3A_chr19_960091_ENST00000263620_length(amino acids)=401AA_BP=37
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEK
GGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAIDSNRREGRRQSFGGSLFAYSPGGAHGMLSS
PKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKK
MALVADEQQRLMQRALQQNFLAMAAQLPMSIRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGG

--------------------------------------------------------------
>81796_81796_3_SHROOM4-ARID3A_SHROOM4_chrX_50556902_ENST00000289292_ARID3A_chr19_960092_ENST00000263620_length(transcript)=5364nt_BP=401nt
CCGTTTTCTTGTCCATTACGCGCTATCCCTCCGCCTCTCCTTCTTTCTTTTCTTTTCTTTTTTTCCCTTCTCCTTTTCCCCCCTCTCTCC
CCCTTTCTCCAGCTCCGTGTCATTTCCTCCTTGCGCTCGCTCGCTGCCTGAGCGTCTCCAGCCGGGAGAGTAGGCGGAGCAGGGCGGTGC
GGGGTGGCGTAGAGCTGGAGGGCGATGGTGGCGGAGCTGCTGGGGGCGGAGGCAACGTAGCCCCCTCGGAAAAGGAGCCCGGCGGCGCCT
GAGCCCAGCCGAGGATGGAGAACCGGCCTGGGTCCTTCCAGTACGTCCCTGTGCAGCTGCAAGGGGGGGCACCCTGGGGCTTCACCCTTA
AGGGGGGTCTGGAACACTGTGAGCCGCTCACAGTGTCTAAGCTCTACGAACTCGACGGGGACCCCAAGAGGAAGGAATTCCTGGATGACT
TGTTCAGCTTCATGCAGAAGCGAGGGACACCTGTGAACCGCATCCCCATCATGGCCAAACAGGTCCTTGACCTGTTCATGCTGTACGTGC
TGGTGACGGAGAAGGGCGGCCTCGTGGAGGTCATCAACAAGAAGCTGTGGCGTGAGATCACCAAGGGCCTCAACCTGCCCACGTCCATCA
CCAGTGCAGCCTTCACCCTGCGGACCCAATACATGAAGTACCTGTACCCCTACGAGTGTGAGAAGCGGGGCCTCAGTAACCCCAATGAGC
TCCAGGCAGCCATAGACAGCAACCGACGGGAGGGCCGGCGCCAGAGCTTTGGTGGCTCCCTCTTTGCCTACTCGCCAGGCGGGGCACACG
GCATGCTCTCCTCACCCAAGCTACCCGTGTCCTCCCTGGGCCTGGCCGCAAGCACCAATGGCAGCTCCATCACCCCCGCCCCTAAGATCA
AGAAAGAGGAGGACTCAGCCATCCCCATCACAGTCCCTGGCCGCCTGCCTGTGTCCCTGGCGGGCCACCCTGTGGTGGCAGCCCAGGCAG
CAGCTGTGCAAGCAGCAGCCGCCCAAGCAGCTGTGGCCGCACAGGCAGCTGCCCTGGAACAGCTGCGGGAGAAGCTGGAGTCTGCAGAGC
CTCCGGAGAAGAAGATGGCCCTGGTGGCCGATGAGCAGCAACGGCTGATGCAACGTGCACTCCAGCAGAACTTCCTGGCCATGGCGGCCC
AGCTGCCCATGAGCATTCGGATCAACAGCCAAGCCTCCGAAAGCCGCCAGGACTCTGCTGTGAACCTGACGGGCACCAACGGCAGCAACA
GCATCAGCATGTCGGTGGAGATCAACGGCATCATGTACACAGGAGTTCTGTTTGCTCAGCCGCCGGCCCCCACGCCAACCTCTGCTCCCA
ACAAAGGAGGCGGCGGCGGCGGCGGCAGCAGCAGCAACGCAGGCGGCCGGGGAGGAAACACCGGAACCAGCGGCGGCCAGGCTGGGCCAG
CGGGGCTGTCCACACCCTCCACATCTACCTCAAATAACTCGTTGCCTTAACCGCATCACTCCCCACCCGCCACCCACCCTGGAGCCCGCC
GGCCTGGGCAGGGGGTCCAGGTGGGCCACACAGGGGCCAGGATGGCGGAAGATACGGGTGGGGAGGGAAGATATCCAGAAAGGAGCCACA
GCTGACGCCAAAAAGAAAAGAAAAAAGATATATATATATATATATATATATACACGTATATATATAAAGAGAATTTAATAAAACAGGGGA
AAACCAAGGAACACTTGAATTTCTCAGGTTTTGGACATTCAGAGAGATGAATTGTGAGAACAGCAAAGAAATCCATCAGAAAAACAGAAA
GAGGCAGACGTTTCCCAGGGCGTTCAGGCAGCCCTGATGGACCGAAGGCTCTGGTGTCTGGTTTGGCCCCACAGCAGTGTGGGCCGATCC
TGTTTACCTCATACATCCCTGCACTGTGTGTTTTCATTTTTGTCTGCTTTAGTTCTCTTTTATTTTCTATTCACCACACACTCACCACTC
CCAGCTTCTCGTGTCCAGTGAAACCCCTGAACCAAGATCACTGAATTTTTGTTTTTTTCTTGTTGCTTTGGGAAATTTTTTTTTCTCTGT
AGGGTTTTTAAGAGGTTTCGGGGGTTTTGTTGTGTAAATATTCTATTTTATTCTTGGGGGGATCAAACCTTAGGAAAAGGATATCTATAT
ATCTATATAGCTATATATTTGTGTTCCTTCAGGGAAACTGGTCTTGAAAAAGCAAGAAAAAAAAGCAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAACTCACCTTTTTATTTTTCCCATGACCAATTTGGGTCCCTTTGTCCATTTCTGGGGGTGCGTTGGGCAGCTGTGAGCCCAGCACA
TCGGATCCCTGGGGCTAGAGCCGCGGAGCCAATGAACTCAGGTGCTATGGGCCGGGCTGGGGCAGAGGGTGCATGCTGGGGTCCCACCGG
CCAGGGGCCCCTGACAGTGAATTGCTGACTGTGATATTCCACGATGCTTTTGCTTGTGCCGTGCTTGTCTGCTGGGCTCTCGAGTCAGGG
GCCTGGAAATTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTTGCTCTTGTCGCCCAGGCTGGAGTGAGTGCAATGGTGCGATCTTGGCT
CACTGCAACCTGCACCTCCCAGGTGCAAGCGATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGATTACAGGCGCCCGCCACCACGCCCAG
TTAATTTTTGTATTTTTAGTAGAGATGGGGGTTTTGCCATGTTGGTCAGGCTGATCTCGAACTCCTGACCTCAGGTGATCTGCCCGCCTT
GGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCGCCACGCTGGCCCGGTCTGGAAATCTTATCTAAAAAGTAGCAAGTGCTGGAAAAA
GGGCCTGGGGGGCGGGGGTGGTTCTTGTCGAAGCCCCCAGGCTCCTGTCTCAGGGATGAATGTGGCGTCTCATTGGGATTCTTCTCTTGC
CCGAAAGGGCTGCTTTTGAGGACTATCAATACTGGGGAGTGGGGGTGAAGCCGGACCTCACTCAGGGTGAGGATTTCAGGGCCCCGGCAT
CCTGAACACCCCCCACACCCCAACATTCTCCTCGCTCTGTCCCTTCCTCTTCTCCCAACCCCTTTTGTGCTGGGGCTGCGAGCTCCCCGA
GTTCTGCGGTGACTAAATCGAGGCCGAGAAGGGAGGCTGCCCCCCACCACCCTGTGGGTCAGTACCCCTCCCCCTGGCTTGGAGAAAGTG
GGGTCACCGCAGCTGAGCTGGGGGGTTATTTTGGCTGGAGCTGCTGGAGCAGAAAGGCTGGGTCTGAAATGCCCAGCAGGGTCTGGGGAC
TTCGTTGGACCCGCGTGGTGTTGGGCGGGGCTGTCGTGTCCTACACGGGAGCTCTGGGCTTTCATTTCTCTTGGGGTGCAGTGGGGATTA
ACTCAGCTATTCCCAGGGTAAGCCTGGGTCTCTAATTGGGCCCTGGGAGCCCTGTTAGGCCACCGGCATGGGGGCTTGGTGAGGAAGGGG
ACTCCCCAGCTCCCCCCACTCCCAACCACCTCCCCATTGCCTTGGAGACCCCTGGGGAGGGGGCTGGGGGGCTTCTGAGCCCCTGAGTCT
AGGTTCACTTTCCCGTCGGGCTGTGGGAGGGGACTGTCACTTTCCTGTGTCTTTGGGGAGGGGACCCCCACTTCCTTCTCGGATCTCAGG
GCCGTGGACACACACCCCCTTTCCAGGAGGGGGTGGTGGGCGTCTAGGTTTTCCTTGTCCCTTCCTGGGGCCAGCACCGTAGCAGCACAA
TCACCCCGGGAAGGGGGTGTCTGTTTGCCTCCAGACACAATCGGGCCCCACTCGCAGAACCACCTGGACTCTGTCCGTGTCTGTCCCCCG
GCCTCCAGGGCTCCTCTCCCGGGACCCCCGTCCCACGCCTGGGCCCCGCGCCGGGGGAAGCGCCTGCTGCCTATCTCTGTCTACCTCAGG
TCTGACTTTTGATGCCAAAATCTGAGCCCCTGGGGTGCCTCTCCCCCGCCTCCCGTGCACCAGGGTCTGCAGCAGCCACTGGGGCCTGGC
TGCCTGCTGCATCTGGCGGCCCTGGACCCCTGGGGCCCCCGTGCACCTGCCCACCTCGGAGCCTGGGGAGGGGCCGTGCAGGGTCGAGGG
CTGGGTCGTCTCCCTCGGGCTGCGTGTGTGTGTCGGGAATCCTGCGTGTCGTGTCTGTGGGCGATCCGGCCTCCCGGCGGTGGGTGGACC
TGGATTCTAACTCAGAGGACTTGAGCCTGCTGTTAACTCCGATGATTGTAGGGACAGGCGGGGTGGGTGGGGGGTGGGCGCGAGGCTGGG
TCCCGGCCCAGGAGAAGGAAGTCGCTGAAGGCAGTGGCCATGCTGGCCGTGGAAATGGGAGGCGGTTGCAGAGGGTCTATGGGGCCCGGT
CCTGGATACTCGGCAGGAAGCCGTGTCTGCAGAGGCTCCTCCCTGCCTCAGGTGGCCCCGTTCAACCCCAGCCGTGCCCATCTCCTGCCA
CCGCCTGTCGGTGGGGGTTTAAATTCGGTGTGGCTTTCTGGGGTGCAGCTCAGCACCCCCCCTTATGCAGACTGGGAGGGGGTCGGGCAG
TCCCCTCAGCCACGAGGACCCTGGATGGGTTCTAGTTCACTTGGGACCGTGGGGCCTGGCTGCGTACTGAGTGGGTGCCCCACAGTCAAG
GCCAACGGGGGCTCCCCCTGCTCTGAGATGTTGGGAGAAAGGCGGCTTCTGGAACCTTCCGTGGGACCCGTAAGTGGCTGTCCAGAAAGG
CGGGAGGGTGGGCACGGGGCACGGGGGGCAGCTGGGGTCGTTGTTAAGGGTCACGCATCTGTACAGTTGAATTTCCTTTCTCTTATCATG
TTTTACCCACCTTGTCCCTTTTTTCCCCAATTGTGCTTTTGCATTTTTTTCCTTGGCAAATGTAAACTCAGCCTTTCATTCATGACGTGT
GAAATTTCAGTTTCTCTGGAGTTTGTCAGACGGCGTGGGAACCACGCCTGAAACTCAGGTAATAGGAGGAAAAAAAAAAAAACTTAAAAA
AATTTTTAAAAAACATAAAACTACTCTCTACCTCTGGCTGGGCCCAGCCTGTCTCGCCCTGGCCGCGGCAGGGTGGCCTGTAACAATTTC
AGTTTTCGCAGAACATTCAGGTATTAAAAGGAAAAAAAAAAAAAAAGACAAAAAGACCAAAAAAAAAAAAAAGTGTGATTTTGAAATTTA
AAAGAACACTGAAAGTTTACATTTTATAGTAACATTATTATGCAGATTGTATTTAAACTTCAGAAATATTTAAGACGATTGTAACCCTGT

>81796_81796_3_SHROOM4-ARID3A_SHROOM4_chrX_50556902_ENST00000289292_ARID3A_chr19_960092_ENST00000263620_length(amino acids)=401AA_BP=37
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEK
GGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAIDSNRREGRRQSFGGSLFAYSPGGAHGMLSS
PKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKK
MALVADEQQRLMQRALQQNFLAMAAQLPMSIRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGG

--------------------------------------------------------------
>81796_81796_4_SHROOM4-ARID3A_SHROOM4_chrX_50556902_ENST00000376020_ARID3A_chr19_960092_ENST00000263620_length(transcript)=5106nt_BP=143nt
CCGGCGGCGCCTGAGCCCAGCCGAGGATGGAGAACCGGCCTGGGTCCTTCCAGTACGTCCCTGTGCAGCTGCAAGGGGGGGCACCCTGGG
GCTTCACCCTTAAGGGGGGTCTGGAACACTGTGAGCCGCTCACAGTGTCTAAGCTCTACGAACTCGACGGGGACCCCAAGAGGAAGGAAT
TCCTGGATGACTTGTTCAGCTTCATGCAGAAGCGAGGGACACCTGTGAACCGCATCCCCATCATGGCCAAACAGGTCCTTGACCTGTTCA
TGCTGTACGTGCTGGTGACGGAGAAGGGCGGCCTCGTGGAGGTCATCAACAAGAAGCTGTGGCGTGAGATCACCAAGGGCCTCAACCTGC
CCACGTCCATCACCAGTGCAGCCTTCACCCTGCGGACCCAATACATGAAGTACCTGTACCCCTACGAGTGTGAGAAGCGGGGCCTCAGTA
ACCCCAATGAGCTCCAGGCAGCCATAGACAGCAACCGACGGGAGGGCCGGCGCCAGAGCTTTGGTGGCTCCCTCTTTGCCTACTCGCCAG
GCGGGGCACACGGCATGCTCTCCTCACCCAAGCTACCCGTGTCCTCCCTGGGCCTGGCCGCAAGCACCAATGGCAGCTCCATCACCCCCG
CCCCTAAGATCAAGAAAGAGGAGGACTCAGCCATCCCCATCACAGTCCCTGGCCGCCTGCCTGTGTCCCTGGCGGGCCACCCTGTGGTGG
CAGCCCAGGCAGCAGCTGTGCAAGCAGCAGCCGCCCAAGCAGCTGTGGCCGCACAGGCAGCTGCCCTGGAACAGCTGCGGGAGAAGCTGG
AGTCTGCAGAGCCTCCGGAGAAGAAGATGGCCCTGGTGGCCGATGAGCAGCAACGGCTGATGCAACGTGCACTCCAGCAGAACTTCCTGG
CCATGGCGGCCCAGCTGCCCATGAGCATTCGGATCAACAGCCAAGCCTCCGAAAGCCGCCAGGACTCTGCTGTGAACCTGACGGGCACCA
ACGGCAGCAACAGCATCAGCATGTCGGTGGAGATCAACGGCATCATGTACACAGGAGTTCTGTTTGCTCAGCCGCCGGCCCCCACGCCAA
CCTCTGCTCCCAACAAAGGAGGCGGCGGCGGCGGCGGCAGCAGCAGCAACGCAGGCGGCCGGGGAGGAAACACCGGAACCAGCGGCGGCC
AGGCTGGGCCAGCGGGGCTGTCCACACCCTCCACATCTACCTCAAATAACTCGTTGCCTTAACCGCATCACTCCCCACCCGCCACCCACC
CTGGAGCCCGCCGGCCTGGGCAGGGGGTCCAGGTGGGCCACACAGGGGCCAGGATGGCGGAAGATACGGGTGGGGAGGGAAGATATCCAG
AAAGGAGCCACAGCTGACGCCAAAAAGAAAAGAAAAAAGATATATATATATATATATATATATACACGTATATATATAAAGAGAATTTAA
TAAAACAGGGGAAAACCAAGGAACACTTGAATTTCTCAGGTTTTGGACATTCAGAGAGATGAATTGTGAGAACAGCAAAGAAATCCATCA
GAAAAACAGAAAGAGGCAGACGTTTCCCAGGGCGTTCAGGCAGCCCTGATGGACCGAAGGCTCTGGTGTCTGGTTTGGCCCCACAGCAGT
GTGGGCCGATCCTGTTTACCTCATACATCCCTGCACTGTGTGTTTTCATTTTTGTCTGCTTTAGTTCTCTTTTATTTTCTATTCACCACA
CACTCACCACTCCCAGCTTCTCGTGTCCAGTGAAACCCCTGAACCAAGATCACTGAATTTTTGTTTTTTTCTTGTTGCTTTGGGAAATTT
TTTTTTCTCTGTAGGGTTTTTAAGAGGTTTCGGGGGTTTTGTTGTGTAAATATTCTATTTTATTCTTGGGGGGATCAAACCTTAGGAAAA
GGATATCTATATATCTATATAGCTATATATTTGTGTTCCTTCAGGGAAACTGGTCTTGAAAAAGCAAGAAAAAAAAGCAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAACTCACCTTTTTATTTTTCCCATGACCAATTTGGGTCCCTTTGTCCATTTCTGGGGGTGCGTTGGGCAGCTGT
GAGCCCAGCACATCGGATCCCTGGGGCTAGAGCCGCGGAGCCAATGAACTCAGGTGCTATGGGCCGGGCTGGGGCAGAGGGTGCATGCTG
GGGTCCCACCGGCCAGGGGCCCCTGACAGTGAATTGCTGACTGTGATATTCCACGATGCTTTTGCTTGTGCCGTGCTTGTCTGCTGGGCT
CTCGAGTCAGGGGCCTGGAAATTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTTGCTCTTGTCGCCCAGGCTGGAGTGAGTGCAATGGT
GCGATCTTGGCTCACTGCAACCTGCACCTCCCAGGTGCAAGCGATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGATTACAGGCGCCCGC
CACCACGCCCAGTTAATTTTTGTATTTTTAGTAGAGATGGGGGTTTTGCCATGTTGGTCAGGCTGATCTCGAACTCCTGACCTCAGGTGA
TCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCGCCACGCTGGCCCGGTCTGGAAATCTTATCTAAAAAGTAGCAA
GTGCTGGAAAAAGGGCCTGGGGGGCGGGGGTGGTTCTTGTCGAAGCCCCCAGGCTCCTGTCTCAGGGATGAATGTGGCGTCTCATTGGGA
TTCTTCTCTTGCCCGAAAGGGCTGCTTTTGAGGACTATCAATACTGGGGAGTGGGGGTGAAGCCGGACCTCACTCAGGGTGAGGATTTCA
GGGCCCCGGCATCCTGAACACCCCCCACACCCCAACATTCTCCTCGCTCTGTCCCTTCCTCTTCTCCCAACCCCTTTTGTGCTGGGGCTG
CGAGCTCCCCGAGTTCTGCGGTGACTAAATCGAGGCCGAGAAGGGAGGCTGCCCCCCACCACCCTGTGGGTCAGTACCCCTCCCCCTGGC
TTGGAGAAAGTGGGGTCACCGCAGCTGAGCTGGGGGGTTATTTTGGCTGGAGCTGCTGGAGCAGAAAGGCTGGGTCTGAAATGCCCAGCA
GGGTCTGGGGACTTCGTTGGACCCGCGTGGTGTTGGGCGGGGCTGTCGTGTCCTACACGGGAGCTCTGGGCTTTCATTTCTCTTGGGGTG
CAGTGGGGATTAACTCAGCTATTCCCAGGGTAAGCCTGGGTCTCTAATTGGGCCCTGGGAGCCCTGTTAGGCCACCGGCATGGGGGCTTG
GTGAGGAAGGGGACTCCCCAGCTCCCCCCACTCCCAACCACCTCCCCATTGCCTTGGAGACCCCTGGGGAGGGGGCTGGGGGGCTTCTGA
GCCCCTGAGTCTAGGTTCACTTTCCCGTCGGGCTGTGGGAGGGGACTGTCACTTTCCTGTGTCTTTGGGGAGGGGACCCCCACTTCCTTC
TCGGATCTCAGGGCCGTGGACACACACCCCCTTTCCAGGAGGGGGTGGTGGGCGTCTAGGTTTTCCTTGTCCCTTCCTGGGGCCAGCACC
GTAGCAGCACAATCACCCCGGGAAGGGGGTGTCTGTTTGCCTCCAGACACAATCGGGCCCCACTCGCAGAACCACCTGGACTCTGTCCGT
GTCTGTCCCCCGGCCTCCAGGGCTCCTCTCCCGGGACCCCCGTCCCACGCCTGGGCCCCGCGCCGGGGGAAGCGCCTGCTGCCTATCTCT
GTCTACCTCAGGTCTGACTTTTGATGCCAAAATCTGAGCCCCTGGGGTGCCTCTCCCCCGCCTCCCGTGCACCAGGGTCTGCAGCAGCCA
CTGGGGCCTGGCTGCCTGCTGCATCTGGCGGCCCTGGACCCCTGGGGCCCCCGTGCACCTGCCCACCTCGGAGCCTGGGGAGGGGCCGTG
CAGGGTCGAGGGCTGGGTCGTCTCCCTCGGGCTGCGTGTGTGTGTCGGGAATCCTGCGTGTCGTGTCTGTGGGCGATCCGGCCTCCCGGC
GGTGGGTGGACCTGGATTCTAACTCAGAGGACTTGAGCCTGCTGTTAACTCCGATGATTGTAGGGACAGGCGGGGTGGGTGGGGGGTGGG
CGCGAGGCTGGGTCCCGGCCCAGGAGAAGGAAGTCGCTGAAGGCAGTGGCCATGCTGGCCGTGGAAATGGGAGGCGGTTGCAGAGGGTCT
ATGGGGCCCGGTCCTGGATACTCGGCAGGAAGCCGTGTCTGCAGAGGCTCCTCCCTGCCTCAGGTGGCCCCGTTCAACCCCAGCCGTGCC
CATCTCCTGCCACCGCCTGTCGGTGGGGGTTTAAATTCGGTGTGGCTTTCTGGGGTGCAGCTCAGCACCCCCCCTTATGCAGACTGGGAG
GGGGTCGGGCAGTCCCCTCAGCCACGAGGACCCTGGATGGGTTCTAGTTCACTTGGGACCGTGGGGCCTGGCTGCGTACTGAGTGGGTGC
CCCACAGTCAAGGCCAACGGGGGCTCCCCCTGCTCTGAGATGTTGGGAGAAAGGCGGCTTCTGGAACCTTCCGTGGGACCCGTAAGTGGC
TGTCCAGAAAGGCGGGAGGGTGGGCACGGGGCACGGGGGGCAGCTGGGGTCGTTGTTAAGGGTCACGCATCTGTACAGTTGAATTTCCTT
TCTCTTATCATGTTTTACCCACCTTGTCCCTTTTTTCCCCAATTGTGCTTTTGCATTTTTTTCCTTGGCAAATGTAAACTCAGCCTTTCA
TTCATGACGTGTGAAATTTCAGTTTCTCTGGAGTTTGTCAGACGGCGTGGGAACCACGCCTGAAACTCAGGTAATAGGAGGAAAAAAAAA
AAAACTTAAAAAAATTTTTAAAAAACATAAAACTACTCTCTACCTCTGGCTGGGCCCAGCCTGTCTCGCCCTGGCCGCGGCAGGGTGGCC
TGTAACAATTTCAGTTTTCGCAGAACATTCAGGTATTAAAAGGAAAAAAAAAAAAAAAGACAAAAAGACCAAAAAAAAAAAAAAGTGTGA
TTTTGAAATTTAAAAGAACACTGAAAGTTTACATTTTATAGTAACATTATTATGCAGATTGTATTTAAACTTCAGAAATATTTAAGACGA

>81796_81796_4_SHROOM4-ARID3A_SHROOM4_chrX_50556902_ENST00000376020_ARID3A_chr19_960092_ENST00000263620_length(amino acids)=401AA_BP=37
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEK
GGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAIDSNRREGRRQSFGGSLFAYSPGGAHGMLSS
PKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKK
MALVADEQQRLMQRALQQNFLAMAAQLPMSIRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGG

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Fusion Gene PPI Analysis for SHROOM4-ARID3A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SHROOM4-ARID3A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SHROOM4-ARID3A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource