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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SIM2-GRIK1 (FusionGDB2 ID:81900) |
Fusion Gene Summary for SIM2-GRIK1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SIM2-GRIK1 | Fusion gene ID: 81900 | Hgene | Tgene | Gene symbol | SIM2 | GRIK1 | Gene ID | 6493 | 2897 |
| Gene name | SIM bHLH transcription factor 2 | glutamate ionotropic receptor kainate type subunit 1 | |
| Synonyms | HMC13F06|HMC29C01|SIM|bHLHe15 | EAA3|EEA3|GLR5|GLUR5|GluK1|gluR-5 | |
| Cytomap | 21q22.13 | 21q21.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | single-minded homolog 2class E basic helix-loop-helix protein 15single-minded family bHLH transcription factor 2transcription factor SIM2 | glutamate receptor ionotropic, kainate 1excitatory amino acid receptor 3glutamate receptor 5 | |
| Modification date | 20200320 | 20200320 | |
| UniProtAcc | . | P39086 | |
| Ensembl transtripts involved in fusion gene | ENST00000460783, ENST00000290399, ENST00000430056, | ENST00000309434, ENST00000327783, ENST00000389124, ENST00000389125, ENST00000399907, ENST00000399909, ENST00000399913, ENST00000399914, ENST00000535441, ENST00000472429, | |
| Fusion gene scores | * DoF score | 3 X 2 X 3=18 | 12 X 9 X 6=648 |
| # samples | 4 | 12 | |
| ** MAII score | log2(4/18*10)=1.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(12/648*10)=-2.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SIM2 [Title/Abstract] AND GRIK1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SIM2(38072221)-GRIK1(31066382), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across SIM2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across GRIK1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LIHC | TCGA-RC-A6M3-01A | SIM2 | chr21 | 38072221 | - | GRIK1 | chr21 | 31066382 | - |
| ChimerDB4 | LIHC | TCGA-RC-A6M3-01A | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
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Fusion Gene ORF analysis for SIM2-GRIK1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000460783 | ENST00000309434 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| 3UTR-3CDS | ENST00000460783 | ENST00000327783 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| 3UTR-3CDS | ENST00000460783 | ENST00000389124 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| 3UTR-3CDS | ENST00000460783 | ENST00000389125 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| 3UTR-3CDS | ENST00000460783 | ENST00000399907 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| 3UTR-3CDS | ENST00000460783 | ENST00000399909 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| 3UTR-3CDS | ENST00000460783 | ENST00000399913 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| 3UTR-3CDS | ENST00000460783 | ENST00000399914 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| 3UTR-3CDS | ENST00000460783 | ENST00000535441 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| 3UTR-5UTR | ENST00000460783 | ENST00000472429 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| 5CDS-5UTR | ENST00000290399 | ENST00000472429 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| 5CDS-5UTR | ENST00000430056 | ENST00000472429 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000290399 | ENST00000309434 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000290399 | ENST00000327783 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000290399 | ENST00000389124 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000290399 | ENST00000389125 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000290399 | ENST00000399907 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000290399 | ENST00000399909 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000290399 | ENST00000399913 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000290399 | ENST00000399914 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000290399 | ENST00000535441 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000430056 | ENST00000309434 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000430056 | ENST00000327783 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000430056 | ENST00000389124 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000430056 | ENST00000389125 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000430056 | ENST00000399907 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000430056 | ENST00000399909 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000430056 | ENST00000399913 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000430056 | ENST00000399914 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| In-frame | ENST00000430056 | ENST00000535441 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000290399 | SIM2 | chr21 | 38072221 | + | ENST00000327783 | GRIK1 | chr21 | 31066382 | - | 3817 | 788 | 613 | 3519 | 968 |
| ENST00000290399 | SIM2 | chr21 | 38072221 | + | ENST00000389125 | GRIK1 | chr21 | 31066382 | - | 3685 | 788 | 613 | 3387 | 924 |
| ENST00000290399 | SIM2 | chr21 | 38072221 | + | ENST00000399913 | GRIK1 | chr21 | 31066382 | - | 3730 | 788 | 613 | 3432 | 939 |
| ENST00000290399 | SIM2 | chr21 | 38072221 | + | ENST00000399914 | GRIK1 | chr21 | 31066382 | - | 3772 | 788 | 613 | 3474 | 953 |
| ENST00000290399 | SIM2 | chr21 | 38072221 | + | ENST00000535441 | GRIK1 | chr21 | 31066382 | - | 3439 | 788 | 613 | 3438 | 942 |
| ENST00000290399 | SIM2 | chr21 | 38072221 | + | ENST00000389124 | GRIK1 | chr21 | 31066382 | - | 3350 | 788 | 613 | 3285 | 890 |
| ENST00000290399 | SIM2 | chr21 | 38072221 | + | ENST00000399907 | GRIK1 | chr21 | 31066382 | - | 3730 | 788 | 613 | 3426 | 937 |
| ENST00000290399 | SIM2 | chr21 | 38072221 | + | ENST00000399909 | GRIK1 | chr21 | 31066382 | - | 3685 | 788 | 613 | 3381 | 922 |
| ENST00000290399 | SIM2 | chr21 | 38072221 | + | ENST00000309434 | GRIK1 | chr21 | 31066382 | - | 3433 | 788 | 613 | 3432 | 940 |
| ENST00000430056 | SIM2 | chr21 | 38072221 | + | ENST00000327783 | GRIK1 | chr21 | 31066382 | - | 3260 | 231 | 56 | 2962 | 968 |
| ENST00000430056 | SIM2 | chr21 | 38072221 | + | ENST00000389125 | GRIK1 | chr21 | 31066382 | - | 3128 | 231 | 56 | 2830 | 924 |
| ENST00000430056 | SIM2 | chr21 | 38072221 | + | ENST00000399913 | GRIK1 | chr21 | 31066382 | - | 3173 | 231 | 56 | 2875 | 939 |
| ENST00000430056 | SIM2 | chr21 | 38072221 | + | ENST00000399914 | GRIK1 | chr21 | 31066382 | - | 3215 | 231 | 56 | 2917 | 953 |
| ENST00000430056 | SIM2 | chr21 | 38072221 | + | ENST00000535441 | GRIK1 | chr21 | 31066382 | - | 2882 | 231 | 56 | 2881 | 942 |
| ENST00000430056 | SIM2 | chr21 | 38072221 | + | ENST00000389124 | GRIK1 | chr21 | 31066382 | - | 2793 | 231 | 56 | 2728 | 890 |
| ENST00000430056 | SIM2 | chr21 | 38072221 | + | ENST00000399907 | GRIK1 | chr21 | 31066382 | - | 3173 | 231 | 56 | 2869 | 937 |
| ENST00000430056 | SIM2 | chr21 | 38072221 | + | ENST00000399909 | GRIK1 | chr21 | 31066382 | - | 3128 | 231 | 56 | 2824 | 922 |
| ENST00000430056 | SIM2 | chr21 | 38072221 | + | ENST00000309434 | GRIK1 | chr21 | 31066382 | - | 2876 | 231 | 56 | 2875 | 940 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000290399 | ENST00000327783 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.001465306 | 0.9985347 |
| ENST00000290399 | ENST00000389125 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.001598476 | 0.9984016 |
| ENST00000290399 | ENST00000399913 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.001462795 | 0.9985372 |
| ENST00000290399 | ENST00000399914 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.001388497 | 0.99861145 |
| ENST00000290399 | ENST00000535441 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.002689552 | 0.9973105 |
| ENST00000290399 | ENST00000389124 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.003558856 | 0.9964412 |
| ENST00000290399 | ENST00000399907 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.001567464 | 0.9984326 |
| ENST00000290399 | ENST00000399909 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.001680275 | 0.9983197 |
| ENST00000290399 | ENST00000309434 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.002210595 | 0.9977894 |
| ENST00000430056 | ENST00000327783 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.000434778 | 0.9995652 |
| ENST00000430056 | ENST00000389125 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.000627834 | 0.9993722 |
| ENST00000430056 | ENST00000399913 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.000552447 | 0.9994475 |
| ENST00000430056 | ENST00000399914 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.000454187 | 0.99954575 |
| ENST00000430056 | ENST00000535441 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.00102782 | 0.9989722 |
| ENST00000430056 | ENST00000389124 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.001522738 | 0.9984773 |
| ENST00000430056 | ENST00000399907 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.000665867 | 0.99933416 |
| ENST00000430056 | ENST00000399909 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.000743056 | 0.9992569 |
| ENST00000430056 | ENST00000309434 | SIM2 | chr21 | 38072221 | + | GRIK1 | chr21 | 31066382 | - | 0.000923387 | 0.9990766 |
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Fusion Genomic Features for SIM2-GRIK1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SIM2-GRIK1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:38072221/chr21:31066382) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | GRIK1 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000290399 | + | 1 | 11 | 1_53 | 58 | 668.0 | Domain | bHLH |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000430056 | + | 1 | 10 | 1_53 | 58 | 571.0 | Domain | bHLH |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000389125 | 0 | 16 | 531_533 | 39 | 906.0 | Region | Glutamate binding | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000389125 | 0 | 16 | 704_705 | 39 | 906.0 | Region | Glutamate binding | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000399907 | 0 | 17 | 531_533 | 39 | 919.0 | Region | Glutamate binding | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000399907 | 0 | 17 | 704_705 | 39 | 919.0 | Region | Glutamate binding | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000389125 | 0 | 16 | 598_653 | 39 | 906.0 | Topological domain | Cytoplasmic | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000389125 | 0 | 16 | 675_834 | 39 | 906.0 | Topological domain | Extracellular | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000389125 | 0 | 16 | 856_918 | 39 | 906.0 | Topological domain | Cytoplasmic | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000399907 | 0 | 17 | 598_653 | 39 | 919.0 | Topological domain | Cytoplasmic | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000399907 | 0 | 17 | 675_834 | 39 | 919.0 | Topological domain | Extracellular | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000399907 | 0 | 17 | 856_918 | 39 | 919.0 | Topological domain | Cytoplasmic | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000389125 | 0 | 16 | 577_597 | 39 | 906.0 | Transmembrane | Helical | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000389125 | 0 | 16 | 654_674 | 39 | 906.0 | Transmembrane | Helical | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000389125 | 0 | 16 | 835_855 | 39 | 906.0 | Transmembrane | Helical | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000399907 | 0 | 17 | 577_597 | 39 | 919.0 | Transmembrane | Helical | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000399907 | 0 | 17 | 654_674 | 39 | 919.0 | Transmembrane | Helical | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000399907 | 0 | 17 | 835_855 | 39 | 919.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000290399 | + | 1 | 11 | 218_288 | 58 | 668.0 | Domain | PAS 2 |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000290399 | + | 1 | 11 | 292_335 | 58 | 668.0 | Domain | Note=PAC |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000290399 | + | 1 | 11 | 336_667 | 58 | 668.0 | Domain | Single-minded C-terminal |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000290399 | + | 1 | 11 | 77_149 | 58 | 668.0 | Domain | PAS 1 |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000430056 | + | 1 | 10 | 218_288 | 58 | 571.0 | Domain | PAS 2 |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000430056 | + | 1 | 10 | 292_335 | 58 | 571.0 | Domain | Note=PAC |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000430056 | + | 1 | 10 | 336_667 | 58 | 571.0 | Domain | Single-minded C-terminal |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000430056 | + | 1 | 10 | 77_149 | 58 | 571.0 | Domain | PAS 1 |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000290399 | + | 1 | 11 | 367_386 | 58 | 668.0 | Motif | Nuclear localization signal |
| Hgene | SIM2 | chr21:38072221 | chr21:31066382 | ENST00000430056 | + | 1 | 10 | 367_386 | 58 | 571.0 | Motif | Nuclear localization signal |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000389125 | 0 | 16 | 31_576 | 39 | 906.0 | Topological domain | Extracellular | |
| Tgene | GRIK1 | chr21:38072221 | chr21:31066382 | ENST00000399907 | 0 | 17 | 31_576 | 39 | 919.0 | Topological domain | Extracellular |
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Fusion Gene Sequence for SIM2-GRIK1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >81900_81900_1_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000309434_length(transcript)=3433nt_BP=788nt CCGCACGTGGACAGCGGAGGTGCTGCGCCTAGCCACACATCGCGGGCTCCGGCGCTGCGTCTCCAGGCACAGGGAGCCGCCAGGAAGGGC AGGAGAGCGCGCCCGGGCCAGGGCCCGGCCCCAGCCGCCTGCGACTCGCTCCCCTCCGCTGGGCTCCCGCTCCATGGCTCCGCGGCCACC GCCGCCCCTGTCGCCCTCCGGTCCGGAGGGGCCTTGCCGCAGCCGGTTCGAGCACTCGACGAAGGAGTAAGCAGCGCCTCCGCCTCCGCG CCGGCCGCCCCCACCCCCCAGGAAGGCCGAGGCAGGAGAGGCAGGAGGGAGGAAACAGGAGCGAGCAGGAACGGGGCTCCGGTTGCTGCA GGACGGTCCAGCCCGGAGGAGGCTGCGCTCCGGGCAGCGGCGGGCGGCGCCGCCGGGTTGCTCGGAGCTCAGGCCCGGCGGCTGCGGGGA GGCGTCTCGGAACCCCGGGAGGCCCCCCGCACCTGCCCGCGGCCCACTCCGCGGACTCACCTGGCTCCCGGCTCCCCCTTCCCCATCCCC GCCGCCGCAGCCCGAGCGGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAA GAATGCGGCCAAGACCAGGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCA GCTGGACAAAGCGTCCATCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGA AAATGAGCCTGTTAATGTTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATT AACCTATGACATCCAGAGAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCT CTTTGGCCCTTCCCATAGCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACA CCCCTCGGTGGACAACAAAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTA TTACAACTGGAAAACAGTGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAA TATTAAAATCAAAATCCGCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGT GATATTTGATTGTTCACATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTT CACAACCCTGGACTTATTTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAA CCCTCACGTGTCATCCATCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGAT GACAACTGAAGCGGCTCTGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCA GTGCCATAGACATAAGCCATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCAACTGCCCGGTGGGATGGCTTGACTGGGCA TATCACCTTTAATAAAACCAATGGCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGG CGAAGTGTCTAAACACTTGTATAAAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGA CAAGTCCAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATC TGATAAGCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGA TGTTAAACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGC TGACCTGGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCAT TCTCTACCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGC CTGCTTGGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGA CGTGGTGGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGC TCTATCGACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGAC AGTAGAGAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAAC AATGACCTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAA CAGTGATGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTG CAACCTCACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTAT TGCTATTCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAA AGAAGCCAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGG AGAATTCATATACAAATCACGGAAGAATAATGATATTGAACAGGCTTTTTGTTTCTTTTATGGACTGCAATGTAAGCAAACCCATCCAAC CAACTCCACTTCTGGAACTACTTTATCTACGGATTTAGAATGTGGTAAATTAATTCGAGAGGAGAGAGGGATTCGAAAACAGTCCTCAGT >81900_81900_1_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000309434_length(amino acids)=940AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEATARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNM TDSNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKE LIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHP CNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGA VRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPY RDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQC -------------------------------------------------------------- >81900_81900_2_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000327783_length(transcript)=3817nt_BP=788nt CCGCACGTGGACAGCGGAGGTGCTGCGCCTAGCCACACATCGCGGGCTCCGGCGCTGCGTCTCCAGGCACAGGGAGCCGCCAGGAAGGGC AGGAGAGCGCGCCCGGGCCAGGGCCCGGCCCCAGCCGCCTGCGACTCGCTCCCCTCCGCTGGGCTCCCGCTCCATGGCTCCGCGGCCACC GCCGCCCCTGTCGCCCTCCGGTCCGGAGGGGCCTTGCCGCAGCCGGTTCGAGCACTCGACGAAGGAGTAAGCAGCGCCTCCGCCTCCGCG CCGGCCGCCCCCACCCCCCAGGAAGGCCGAGGCAGGAGAGGCAGGAGGGAGGAAACAGGAGCGAGCAGGAACGGGGCTCCGGTTGCTGCA GGACGGTCCAGCCCGGAGGAGGCTGCGCTCCGGGCAGCGGCGGGCGGCGCCGCCGGGTTGCTCGGAGCTCAGGCCCGGCGGCTGCGGGGA GGCGTCTCGGAACCCCGGGAGGCCCCCCGCACCTGCCCGCGGCCCACTCCGCGGACTCACCTGGCTCCCGGCTCCCCCTTCCCCATCCCC GCCGCCGCAGCCCGAGCGGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAA GAATGCGGCCAAGACCAGGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCA GCTGGACAAAGCGTCCATCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGA AAATGAGCCTGTTAATGTTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATT AACCTATGACATCCAGAGAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCT CTTTGGCCCTTCCCATAGCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACA CCCCTCGGTGGACAACAAAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTA TTACAACTGGAAAACAGTGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAA TATTAAAATCAAAATCCGCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGT GATATTTGATTGTTCACATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTT CACAACCCTGGACTTATTTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAA CCCTCACGTGTCATCCATCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGAT GACAACTGAAGCGGCTCTGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCA GTGCCATAGACATAAGCCATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCAC CTTTAATAAAACCAATGGCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGGCGAAGT GTCTAAACACTTGTATAAAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTC CAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAA GCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAA ACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCT GGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTA CCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTT GGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGT GGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATC GACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGA GAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGAC CTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGA TGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCT CACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTAT TCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGC CAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATT CATATACAAATCACGGAAGAATAATGATATTGAACAGAAAGGAAAGTCATCAAGAATTAGATTTTATTTTAGGAACAAAGTAAGGTTTCA TGGGAGAAAAAAACAAAGCCTTGGTGTAGAGAAGTGTCTCTCTTTCAACGCTATCATGGAAGAACTGGGAATCTCACTGAAGAATCAGAA AAAAATAAAGAAAAAGTCAAGAACTAAGGGGAAATCTTCCTTCACAAGTATCCTTACTTGTCATCAGAGACGAACTCAGAGAAAAGAGAC TGTGGCGTGATCCAAGGAAACGCCTGTAGGAAGAAAAAGGATGCATTCCCTACAGATTTTTGGAGAAAGGATTTCTGAGGAGTGTGTGAT GTGTTTCCATATATCTATATCCATAACTCTGATTATGAATACAGATATAAGAAATACAAAAGTTTAAAAAGCTCACATAGATATGACTTG GGAAGTGACACCAGTTCTTTTAAAATAAATTTGTATGCTCAATTATTTTGCATTTTTTCTTTTTCCCCAATAAATTGTTGTGTGTGCTTT >81900_81900_2_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000327783_length(amino acids)=968AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTD SNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELI DHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCN PDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVR DGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRD KITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQKGKSSRIRFYFR -------------------------------------------------------------- >81900_81900_3_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000389124_length(transcript)=3350nt_BP=788nt CCGCACGTGGACAGCGGAGGTGCTGCGCCTAGCCACACATCGCGGGCTCCGGCGCTGCGTCTCCAGGCACAGGGAGCCGCCAGGAAGGGC AGGAGAGCGCGCCCGGGCCAGGGCCCGGCCCCAGCCGCCTGCGACTCGCTCCCCTCCGCTGGGCTCCCGCTCCATGGCTCCGCGGCCACC GCCGCCCCTGTCGCCCTCCGGTCCGGAGGGGCCTTGCCGCAGCCGGTTCGAGCACTCGACGAAGGAGTAAGCAGCGCCTCCGCCTCCGCG CCGGCCGCCCCCACCCCCCAGGAAGGCCGAGGCAGGAGAGGCAGGAGGGAGGAAACAGGAGCGAGCAGGAACGGGGCTCCGGTTGCTGCA GGACGGTCCAGCCCGGAGGAGGCTGCGCTCCGGGCAGCGGCGGGCGGCGCCGCCGGGTTGCTCGGAGCTCAGGCCCGGCGGCTGCGGGGA GGCGTCTCGGAACCCCGGGAGGCCCCCCGCACCTGCCCGCGGCCCACTCCGCGGACTCACCTGGCTCCCGGCTCCCCCTTCCCCATCCCC GCCGCCGCAGCCCGAGCGGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAA GAATGCGGCCAAGACCAGGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCA GCTGGACAAAGCGTCCATCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGA AAATGAGCCTGTTAATGTTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATT AACCTATGACATCCAGAGAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCT CTTTGGCCCTTCCCATAGCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACA CCCCTCGGTGGACAACAAAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTA TTACAACTGGAAAACAGTGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAA TATTAAAATCAAAATCCGCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGT GATATTTGATTGTTCACATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTT CACAACCCTGGACTTATTTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAA CCCTCACGTGTCATCCATCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGAT GACAACTGAAGCGGCTCTGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCA GTGCCATAGACATAAGCCATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCAC CTTTAATAAAACCAATGGCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGGCGAAGT GTCTAAACACTTGTATAAAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTC CAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAA GCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAA ACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCT GGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTA CCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTT GGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGT GGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATC GACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGA GAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGAC CTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGA TGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCT CACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTAT TCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGC CAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATT CATATACAAATCACGGAAGAATAATGATATTGAACAGCATTACTGAAGTGTCCGTATGCCTTGATAATCCTATCAATGTTTGGATCATCT >81900_81900_3_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000389124_length(amino acids)=890AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTD SNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELI DHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCN PDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVR DGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRD -------------------------------------------------------------- >81900_81900_4_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000389125_length(transcript)=3685nt_BP=788nt CCGCACGTGGACAGCGGAGGTGCTGCGCCTAGCCACACATCGCGGGCTCCGGCGCTGCGTCTCCAGGCACAGGGAGCCGCCAGGAAGGGC AGGAGAGCGCGCCCGGGCCAGGGCCCGGCCCCAGCCGCCTGCGACTCGCTCCCCTCCGCTGGGCTCCCGCTCCATGGCTCCGCGGCCACC GCCGCCCCTGTCGCCCTCCGGTCCGGAGGGGCCTTGCCGCAGCCGGTTCGAGCACTCGACGAAGGAGTAAGCAGCGCCTCCGCCTCCGCG CCGGCCGCCCCCACCCCCCAGGAAGGCCGAGGCAGGAGAGGCAGGAGGGAGGAAACAGGAGCGAGCAGGAACGGGGCTCCGGTTGCTGCA GGACGGTCCAGCCCGGAGGAGGCTGCGCTCCGGGCAGCGGCGGGCGGCGCCGCCGGGTTGCTCGGAGCTCAGGCCCGGCGGCTGCGGGGA GGCGTCTCGGAACCCCGGGAGGCCCCCCGCACCTGCCCGCGGCCCACTCCGCGGACTCACCTGGCTCCCGGCTCCCCCTTCCCCATCCCC GCCGCCGCAGCCCGAGCGGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAA GAATGCGGCCAAGACCAGGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCA GCTGGACAAAGCGTCCATCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGA AAATGAGCCTGTTAATGTTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATT AACCTATGACATCCAGAGAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCT CTTTGGCCCTTCCCATAGCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACA CCCCTCGGTGGACAACAAAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTA TTACAACTGGAAAACAGTGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAA TATTAAAATCAAAATCCGCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGT GATATTTGATTGTTCACATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTT CACAACCCTGGACTTATTTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAA CCCTCACGTGTCATCCATCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGAT GACAACTGAAGCGGCTCTGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCA GTGCCATAGACATAAGCCATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCAC CTTTAATAAAACCAATGGCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGATTGGGATTTGGAA TTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCAC CACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCT GTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGA GTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCAT TGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAA CCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTA CGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGG AGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCAT CATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCA AACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGC TTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGAT GGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGG AACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAA GTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCT GGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAATCACGGAAGAATAATGATATTGAACAGTGTCTCTC TTTCAACGCTATCATGGAAGAACTGGGAATCTCACTGAAGAATCAGAAAAAAATAAAGAAAAAGTCAAGAACTAAGGGGAAATCTTCCTT CACAAGTATCCTTACTTGTCATCAGAGACGAACTCAGAGAAAAGAGACTGTGGCGTGATCCAAGGAAACGCCTGTAGGAAGAAAAAGGAT GCATTCCCTACAGATTTTTGGAGAAAGGATTTCTGAGGAGTGTGTGATGTGTTTCCATATATCTATATCCATAACTCTGATTATGAATAC AGATATAAGAAATACAAAAGTTTAAAAAGCTCACATAGATATGACTTGGGAAGTGACACCAGTTCTTTTAAAATAAATTTGTATGCTCAA >81900_81900_4_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000389125_length(amino acids)=924AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLAN RTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITY VREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNS FWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKIST YEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKL HMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQCLSFNAIMEELGISLKNQKKIKKKSRT -------------------------------------------------------------- >81900_81900_5_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000399907_length(transcript)=3730nt_BP=788nt CCGCACGTGGACAGCGGAGGTGCTGCGCCTAGCCACACATCGCGGGCTCCGGCGCTGCGTCTCCAGGCACAGGGAGCCGCCAGGAAGGGC AGGAGAGCGCGCCCGGGCCAGGGCCCGGCCCCAGCCGCCTGCGACTCGCTCCCCTCCGCTGGGCTCCCGCTCCATGGCTCCGCGGCCACC GCCGCCCCTGTCGCCCTCCGGTCCGGAGGGGCCTTGCCGCAGCCGGTTCGAGCACTCGACGAAGGAGTAAGCAGCGCCTCCGCCTCCGCG CCGGCCGCCCCCACCCCCCAGGAAGGCCGAGGCAGGAGAGGCAGGAGGGAGGAAACAGGAGCGAGCAGGAACGGGGCTCCGGTTGCTGCA GGACGGTCCAGCCCGGAGGAGGCTGCGCTCCGGGCAGCGGCGGGCGGCGCCGCCGGGTTGCTCGGAGCTCAGGCCCGGCGGCTGCGGGGA GGCGTCTCGGAACCCCGGGAGGCCCCCCGCACCTGCCCGCGGCCCACTCCGCGGACTCACCTGGCTCCCGGCTCCCCCTTCCCCATCCCC GCCGCCGCAGCCCGAGCGGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAA GAATGCGGCCAAGACCAGGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCA GCTGGACAAAGCGTCCATCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGA AAATGAGCCTGTTAATGTTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATT AACCTATGACATCCAGAGAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCT CTTTGGCCCTTCCCATAGCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACA CCCCTCGGTGGACAACAAAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTA TTACAACTGGAAAACAGTGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAA TATTAAAATCAAAATCCGCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGT GATATTTGATTGTTCACATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTT CACAACCCTGGACTTATTTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAA CCCTCACGTGTCATCCATCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGAT GACAACTGAAGCGGCTCTGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCA GTGCCATAGACATAAGCCATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCAC CTTTAATAAAACCAATGGCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGGCGAAGT GTCTAAACACTTGTATAAAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTC CAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAA GCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAA ACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCT GGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTA CCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTT GGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGT GGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATC GACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGA GAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGAC CTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGA TGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCT CACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTAT TCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGC CAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATT CATATACAAATCACGGAAGAATAATGATATTGAACAGGCTTTTTGTTTCTTTTATGGACTGCAATGTAAGCAAACCCATCCAACCAACTC CACTTCTGGAACTACTTTATCTACGGATTTAGAATGTGGTAAATTAATTCGAGAGGAGAGAGGGATTCGAAAACAGTCCTCAGTTCATAC TGTGTAATCAGTTTAAAAAAAAAAAAAAAGATGTGCCCAGTAGAAAATGTTTTTGCTAATTGGTGTTGTTGATATTTGTATTTGCTAAGC ATAAATAGCCACAATTCTCTATTCCTTTAGGATAGCAAAACTCATGTATTCTAGACATTGAAATGAATACACTGGAAAGATACTTGCACT GTATGTTGAAGCAGGGGCATATTAGGGGTATAAAGACTTCTAGAAATGTGTATTTACAGGAATCTTCTCTGTCCCACTCATCATCTTAGT >81900_81900_5_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000399907_length(amino acids)=937AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTD SNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELI DHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCN PDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVR DGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRD KITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQCKQ -------------------------------------------------------------- >81900_81900_6_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000399909_length(transcript)=3685nt_BP=788nt CCGCACGTGGACAGCGGAGGTGCTGCGCCTAGCCACACATCGCGGGCTCCGGCGCTGCGTCTCCAGGCACAGGGAGCCGCCAGGAAGGGC AGGAGAGCGCGCCCGGGCCAGGGCCCGGCCCCAGCCGCCTGCGACTCGCTCCCCTCCGCTGGGCTCCCGCTCCATGGCTCCGCGGCCACC GCCGCCCCTGTCGCCCTCCGGTCCGGAGGGGCCTTGCCGCAGCCGGTTCGAGCACTCGACGAAGGAGTAAGCAGCGCCTCCGCCTCCGCG CCGGCCGCCCCCACCCCCCAGGAAGGCCGAGGCAGGAGAGGCAGGAGGGAGGAAACAGGAGCGAGCAGGAACGGGGCTCCGGTTGCTGCA GGACGGTCCAGCCCGGAGGAGGCTGCGCTCCGGGCAGCGGCGGGCGGCGCCGCCGGGTTGCTCGGAGCTCAGGCCCGGCGGCTGCGGGGA GGCGTCTCGGAACCCCGGGAGGCCCCCCGCACCTGCCCGCGGCCCACTCCGCGGACTCACCTGGCTCCCGGCTCCCCCTTCCCCATCCCC GCCGCCGCAGCCCGAGCGGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAA GAATGCGGCCAAGACCAGGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCA GCTGGACAAAGCGTCCATCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGA AAATGAGCCTGTTAATGTTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATT AACCTATGACATCCAGAGAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCT CTTTGGCCCTTCCCATAGCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACA CCCCTCGGTGGACAACAAAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTA TTACAACTGGAAAACAGTGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAA TATTAAAATCAAAATCCGCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGT GATATTTGATTGTTCACATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTT CACAACCCTGGACTTATTTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAA CCCTCACGTGTCATCCATCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGAT GACAACTGAAGCGGCTCTGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCA GTGCCATAGACATAAGCCATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCAC CTTTAATAAAACCAATGGCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGATTGGGATTTGGAA TTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCAC CACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCT GTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGA GTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCAT TGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAA CCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTA CGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGG AGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCAT CATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCA AACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGC TTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGAT GGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGG AACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAA GTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCT GGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAATCACGGAAGAATAATGATATTGAACAGGCTTTTTG TTTCTTTTATGGACTGCAATGTAAGCAAACCCATCCAACCAACTCCACTTCTGGAACTACTTTATCTACGGATTTAGAATGTGGTAAATT AATTCGAGAGGAGAGAGGGATTCGAAAACAGTCCTCAGTTCATACTGTGTAATCAGTTTAAAAAAAAAAAAAAAGATGTGCCCAGTAGAA AATGTTTTTGCTAATTGGTGTTGTTGATATTTGTATTTGCTAAGCATAAATAGCCACAATTCTCTATTCCTTTAGGATAGCAAAACTCAT GTATTCTAGACATTGAAATGAATACACTGGAAAGATACTTGCACTGTATGTTGAAGCAGGGGCATATTAGGGGTATAAAGACTTCTAGAA >81900_81900_6_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000399909_length(amino acids)=922AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLAN RTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITY VREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNS FWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKIST YEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKL HMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQCKQTHPTNSTSGTTLSTD -------------------------------------------------------------- >81900_81900_7_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000399913_length(transcript)=3730nt_BP=788nt CCGCACGTGGACAGCGGAGGTGCTGCGCCTAGCCACACATCGCGGGCTCCGGCGCTGCGTCTCCAGGCACAGGGAGCCGCCAGGAAGGGC AGGAGAGCGCGCCCGGGCCAGGGCCCGGCCCCAGCCGCCTGCGACTCGCTCCCCTCCGCTGGGCTCCCGCTCCATGGCTCCGCGGCCACC GCCGCCCCTGTCGCCCTCCGGTCCGGAGGGGCCTTGCCGCAGCCGGTTCGAGCACTCGACGAAGGAGTAAGCAGCGCCTCCGCCTCCGCG CCGGCCGCCCCCACCCCCCAGGAAGGCCGAGGCAGGAGAGGCAGGAGGGAGGAAACAGGAGCGAGCAGGAACGGGGCTCCGGTTGCTGCA GGACGGTCCAGCCCGGAGGAGGCTGCGCTCCGGGCAGCGGCGGGCGGCGCCGCCGGGTTGCTCGGAGCTCAGGCCCGGCGGCTGCGGGGA GGCGTCTCGGAACCCCGGGAGGCCCCCCGCACCTGCCCGCGGCCCACTCCGCGGACTCACCTGGCTCCCGGCTCCCCCTTCCCCATCCCC GCCGCCGCAGCCCGAGCGGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAA GAATGCGGCCAAGACCAGGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCA GCTGGACAAAGCGTCCATCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGA AAATGAGCCTGTTAATGTTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATT AACCTATGACATCCAGAGAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCT CTTTGGCCCTTCCCATAGCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACA CCCCTCGGTGGACAACAAAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTA TTACAACTGGAAAACAGTGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAA TATTAAAATCAAAATCCGCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGT GATATTTGATTGTTCACATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTT CACAACCCTGGACTTATTTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAA CCCTCACGTGTCATCCATCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGAT GACAACTGAAGCGGCTCTGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCA GTGCCATAGACATAAGCCATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCAC CTTTAATAAAACCAATGGCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGGCGAAGT GTCTAAACACTTGTATAAAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTC CAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAA GCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAA ACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCT GGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTA CCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTT GGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGT GGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATC GACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGA GAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGAC CTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGA TGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCT CACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTAT TCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGC CAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATT CATATACAAATCACGGAAGAATAATGATATTGAACAGTGTCTCTCTTTCAACGCTATCATGGAAGAACTGGGAATCTCACTGAAGAATCA GAAAAAAATAAAGAAAAAGTCAAGAACTAAGGGGAAATCTTCCTTCACAAGTATCCTTACTTGTCATCAGAGACGAACTCAGAGAAAAGA GACTGTGGCGTGATCCAAGGAAACGCCTGTAGGAAGAAAAAGGATGCATTCCCTACAGATTTTTGGAGAAAGGATTTCTGAGGAGTGTGT GATGTGTTTCCATATATCTATATCCATAACTCTGATTATGAATACAGATATAAGAAATACAAAAGTTTAAAAAGCTCACATAGATATGAC TTGGGAAGTGACACCAGTTCTTTTAAAATAAATTTGTATGCTCAATTATTTTGCATTTTTTCTTTTTCCCCAATAAATTGTTGTGTGTGC >81900_81900_7_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000399913_length(amino acids)=939AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTD SNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELI DHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCN PDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVR DGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRD KITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQCLSFNAIMEELG -------------------------------------------------------------- >81900_81900_8_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000399914_length(transcript)=3772nt_BP=788nt CCGCACGTGGACAGCGGAGGTGCTGCGCCTAGCCACACATCGCGGGCTCCGGCGCTGCGTCTCCAGGCACAGGGAGCCGCCAGGAAGGGC AGGAGAGCGCGCCCGGGCCAGGGCCCGGCCCCAGCCGCCTGCGACTCGCTCCCCTCCGCTGGGCTCCCGCTCCATGGCTCCGCGGCCACC GCCGCCCCTGTCGCCCTCCGGTCCGGAGGGGCCTTGCCGCAGCCGGTTCGAGCACTCGACGAAGGAGTAAGCAGCGCCTCCGCCTCCGCG CCGGCCGCCCCCACCCCCCAGGAAGGCCGAGGCAGGAGAGGCAGGAGGGAGGAAACAGGAGCGAGCAGGAACGGGGCTCCGGTTGCTGCA GGACGGTCCAGCCCGGAGGAGGCTGCGCTCCGGGCAGCGGCGGGCGGCGCCGCCGGGTTGCTCGGAGCTCAGGCCCGGCGGCTGCGGGGA GGCGTCTCGGAACCCCGGGAGGCCCCCCGCACCTGCCCGCGGCCCACTCCGCGGACTCACCTGGCTCCCGGCTCCCCCTTCCCCATCCCC GCCGCCGCAGCCCGAGCGGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAA GAATGCGGCCAAGACCAGGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCA GCTGGACAAAGCGTCCATCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGA AAATGAGCCTGTTAATGTTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATT AACCTATGACATCCAGAGAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCT CTTTGGCCCTTCCCATAGCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACA CCCCTCGGTGGACAACAAAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTA TTACAACTGGAAAACAGTGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAA TATTAAAATCAAAATCCGCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGT GATATTTGATTGTTCACATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTT CACAACCCTGGACTTATTTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAA CCCTCACGTGTCATCCATCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGAT GACAACTGAAGCGGCTCTGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCA GTGCCATAGACATAAGCCATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCAC CTTTAATAAAACCAATGGCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGATTGGGATTTGGAA TTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCAC CACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCT GTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGA GTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCAT TGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAA CCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTA CGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGG AGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCAT CATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCA AACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGC TTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGAT GGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGG AACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAA GTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCT GGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAATCACGGAAGAATAATGATATTGAACAGAAAGGAAA GTCATCAAGAATTAGATTTTATTTTAGGAACAAAGTAAGGTTTCATGGGAGAAAAAAACAAAGCCTTGGTGTAGAGAAGTGTCTCTCTTT CAACGCTATCATGGAAGAACTGGGAATCTCACTGAAGAATCAGAAAAAAATAAAGAAAAAGTCAAGAACTAAGGGGAAATCTTCCTTCAC AAGTATCCTTACTTGTCATCAGAGACGAACTCAGAGAAAAGAGACTGTGGCGTGATCCAAGGAAACGCCTGTAGGAAGAAAAAGGATGCA TTCCCTACAGATTTTTGGAGAAAGGATTTCTGAGGAGTGTGTGATGTGTTTCCATATATCTATATCCATAACTCTGATTATGAATACAGA TATAAGAAATACAAAAGTTTAAAAAGCTCACATAGATATGACTTGGGAAGTGACACCAGTTCTTTTAAAATAAATTTGTATGCTCAATTA >81900_81900_8_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000399914_length(amino acids)=953AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLAN RTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITY VREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNS FWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKIST YEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKL HMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQKGKSSRIRFYFRNKVRFHGRKKQSLGV -------------------------------------------------------------- >81900_81900_9_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000535441_length(transcript)=3439nt_BP=788nt CCGCACGTGGACAGCGGAGGTGCTGCGCCTAGCCACACATCGCGGGCTCCGGCGCTGCGTCTCCAGGCACAGGGAGCCGCCAGGAAGGGC AGGAGAGCGCGCCCGGGCCAGGGCCCGGCCCCAGCCGCCTGCGACTCGCTCCCCTCCGCTGGGCTCCCGCTCCATGGCTCCGCGGCCACC GCCGCCCCTGTCGCCCTCCGGTCCGGAGGGGCCTTGCCGCAGCCGGTTCGAGCACTCGACGAAGGAGTAAGCAGCGCCTCCGCCTCCGCG CCGGCCGCCCCCACCCCCCAGGAAGGCCGAGGCAGGAGAGGCAGGAGGGAGGAAACAGGAGCGAGCAGGAACGGGGCTCCGGTTGCTGCA GGACGGTCCAGCCCGGAGGAGGCTGCGCTCCGGGCAGCGGCGGGCGGCGCCGCCGGGTTGCTCGGAGCTCAGGCCCGGCGGCTGCGGGGA GGCGTCTCGGAACCCCGGGAGGCCCCCCGCACCTGCCCGCGGCCCACTCCGCGGACTCACCTGGCTCCCGGCTCCCCCTTCCCCATCCCC GCCGCCGCAGCCCGAGCGGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAA GAATGCGGCCAAGACCAGGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCA GCTGGACAAAGCGTCCATCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGA AAATGAGCCTGTTAATGTTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATT AACCTATGACATCCAGAGAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCT CTTTGGCCCTTCCCATAGCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACA CCCCTCGGTGGACAACAAAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTA TTACAACTGGAAAACAGTGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAA TATTAAAATCAAAATCCGCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGT GATATTTGATTGTTCACATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTT CACAACCCTGGACTTATTTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAA CCCTCACGTGTCATCCATCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGAT GACAACTGAAGCGGCTCTGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCA GTGCCATAGACATAAGCCATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCAACTGCCCGGTGGGATGGCTTGACTGGGCA TATCACCTTTAATAAAACCAATGGCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGG CGAAGTGTCTAAACACTTGTATAAAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGA CAAGTCCAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATC TGATAAGCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGA TGTTAAACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGC TGACCTGGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCAT TCTCTACCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGC CTGCTTGGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGA CGTGGTGGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGC TCTATCGACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGAC AGTAGAGAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAAC AATGACCTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAA CAGTGATGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTG CAACCTCACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTAT TGCTATTCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAA AGAAGCCAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGG AGAATTCATATACAAATCACGGAAGAATAATGATATTGAACAGTGTCTCTCTTTCAACGCTATCATGGAAGAACTGGGAATCTCACTGAA GAATCAGAAAAAAATAAAGAAAAAGTCAAGAACTAAGGGGAAATCTTCCTTCACAAGTATCCTTACTTGTCATCAGAGACGAACTCAGAG >81900_81900_9_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000290399_GRIK1_chr21_31066382_ENST00000535441_length(amino acids)=942AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEATARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNM TDSNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKE LIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHP CNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGA VRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPY RDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQCLSFNAIMEE -------------------------------------------------------------- >81900_81900_10_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000309434_length(transcript)=2876nt_BP=231nt GGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAAGAATGCGGCCAAGACCA GGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCAGCTGGACAAAGCGTCCA TCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGAAAATGAGCCTGTTAATG TTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATTAACCTATGACATCCAGA GAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCTCTTTGGCCCTTCCCATA GCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACACCCCTCGGTGGACAACA AAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTATTACAACTGGAAAACAG TGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAATATTAAAATCAAAATCC GCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGTGATATTTGATTGTTCAC ATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTTCACAACCCTGGACTTAT TTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAACCCTCACGTGTCATCCA TCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGATGACAACTGAAGCGGCTC TGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCAGTGCCATAGACATAAGC CATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCAACTGCCCGGTGGGATGGCTTGACTGGGCATATCACCTTTAATAAAA CCAATGGCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGGCGAAGTGTCTAAACACT TGTATAAAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCA CTGATTCATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATG GAAATGACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCG ATGGCAAATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTC CTCTTACCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCA ATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCT GTGTACTCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATT TTACTTTACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAG TTGGAGGGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAAT CCCCCATAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGA AATCAAAAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCC AGAGAGTGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCG GGGGCCTCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCC AAGAAGAAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGG GAGTGGAAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAAT CACGGAAGAATAATGATATTGAACAGGCTTTTTGTTTCTTTTATGGACTGCAATGTAAGCAAACCCATCCAACCAACTCCACTTCTGGAA >81900_81900_10_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000309434_length(amino acids)=940AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEATARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNM TDSNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKE LIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHP CNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGA VRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPY RDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQC -------------------------------------------------------------- >81900_81900_11_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000327783_length(transcript)=3260nt_BP=231nt GGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAAGAATGCGGCCAAGACCA GGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCAGCTGGACAAAGCGTCCA TCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGAAAATGAGCCTGTTAATG TTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATTAACCTATGACATCCAGA GAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCTCTTTGGCCCTTCCCATA GCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACACCCCTCGGTGGACAACA AAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTATTACAACTGGAAAACAG TGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAATATTAAAATCAAAATCC GCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGTGATATTTGATTGTTCAC ATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTTCACAACCCTGGACTTAT TTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAACCCTCACGTGTCATCCA TCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGATGACAACTGAAGCGGCTC TGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCAGTGCCATAGACATAAGC CATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCACCTTTAATAAAACCAATG GCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGGCGAAGTGTCTAAACACTTGTATA AAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCACTGATT CATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATGGAAATG ACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCGATGGCA AATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTCCTCTTA CCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCAATGGTA CCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCTGTGTAC TCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACTT TACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAGTTGGAG GGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAATCCCCCA TAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGAAATCAA AAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCCAGAGAG TGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCGGGGGCC TCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCCAAGAAG AAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGGGAGTGG AAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAATCACGGA AGAATAATGATATTGAACAGAAAGGAAAGTCATCAAGAATTAGATTTTATTTTAGGAACAAAGTAAGGTTTCATGGGAGAAAAAAACAAA GCCTTGGTGTAGAGAAGTGTCTCTCTTTCAACGCTATCATGGAAGAACTGGGAATCTCACTGAAGAATCAGAAAAAAATAAAGAAAAAGT CAAGAACTAAGGGGAAATCTTCCTTCACAAGTATCCTTACTTGTCATCAGAGACGAACTCAGAGAAAAGAGACTGTGGCGTGATCCAAGG AAACGCCTGTAGGAAGAAAAAGGATGCATTCCCTACAGATTTTTGGAGAAAGGATTTCTGAGGAGTGTGTGATGTGTTTCCATATATCTA TATCCATAACTCTGATTATGAATACAGATATAAGAAATACAAAAGTTTAAAAAGCTCACATAGATATGACTTGGGAAGTGACACCAGTTC TTTTAAAATAAATTTGTATGCTCAATTATTTTGCATTTTTTCTTTTTCCCCAATAAATTGTTGTGTGTGCTTTCTAAATAATAATAAAAC >81900_81900_11_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000327783_length(amino acids)=968AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTD SNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELI DHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCN PDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVR DGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRD KITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQKGKSSRIRFYFR -------------------------------------------------------------- >81900_81900_12_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000389124_length(transcript)=2793nt_BP=231nt GGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAAGAATGCGGCCAAGACCA GGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCAGCTGGACAAAGCGTCCA TCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGAAAATGAGCCTGTTAATG TTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATTAACCTATGACATCCAGA GAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCTCTTTGGCCCTTCCCATA GCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACACCCCTCGGTGGACAACA AAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTATTACAACTGGAAAACAG TGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAATATTAAAATCAAAATCC GCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGTGATATTTGATTGTTCAC ATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTTCACAACCCTGGACTTAT TTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAACCCTCACGTGTCATCCA TCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGATGACAACTGAAGCGGCTC TGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCAGTGCCATAGACATAAGC CATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCACCTTTAATAAAACCAATG GCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGGCGAAGTGTCTAAACACTTGTATA AAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCACTGATT CATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATGGAAATG ACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCGATGGCA AATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTCCTCTTA CCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCAATGGTA CCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCTGTGTAC TCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACTT TACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAGTTGGAG GGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAATCCCCCA TAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGAAATCAA AAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCCAGAGAG TGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCGGGGGCC TCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCCAAGAAG AAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGGGAGTGG AAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAATCACGGA AGAATAATGATATTGAACAGCATTACTGAAGTGTCCGTATGCCTTGATAATCCTATCAATGTTTGGATCATCTCAGTGGGGGAAATGACT >81900_81900_12_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000389124_length(amino acids)=890AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTD SNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELI DHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCN PDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVR DGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRD -------------------------------------------------------------- >81900_81900_13_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000389125_length(transcript)=3128nt_BP=231nt GGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAAGAATGCGGCCAAGACCA GGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCAGCTGGACAAAGCGTCCA TCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGAAAATGAGCCTGTTAATG TTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATTAACCTATGACATCCAGA GAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCTCTTTGGCCCTTCCCATA GCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACACCCCTCGGTGGACAACA AAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTATTACAACTGGAAAACAG TGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAATATTAAAATCAAAATCC GCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGTGATATTTGATTGTTCAC ATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTTCACAACCCTGGACTTAT TTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAACCCTCACGTGTCATCCA TCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGATGACAACTGAAGCGGCTC TGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCAGTGCCATAGACATAAGC CATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCACCTTTAATAAAACCAATG GCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGATTGGGATTTGGAATTCCAACAGTGGGCTTA ACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAAC CCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAA ACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTA AAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCT TCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATA TTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCC ACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAG GATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGG CCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATG GGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGC AGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTG AGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTC CTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATG GCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCC TTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAATCACGGAAGAATAATGATATTGAACAGTGTCTCTCTTTCAACGCTATCATGG AAGAACTGGGAATCTCACTGAAGAATCAGAAAAAAATAAAGAAAAAGTCAAGAACTAAGGGGAAATCTTCCTTCACAAGTATCCTTACTT GTCATCAGAGACGAACTCAGAGAAAAGAGACTGTGGCGTGATCCAAGGAAACGCCTGTAGGAAGAAAAAGGATGCATTCCCTACAGATTT TTGGAGAAAGGATTTCTGAGGAGTGTGTGATGTGTTTCCATATATCTATATCCATAACTCTGATTATGAATACAGATATAAGAAATACAA AAGTTTAAAAAGCTCACATAGATATGACTTGGGAAGTGACACCAGTTCTTTTAAAATAAATTTGTATGCTCAATTATTTTGCATTTTTTC >81900_81900_13_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000389125_length(amino acids)=924AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLAN RTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITY VREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNS FWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKIST YEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKL HMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQCLSFNAIMEELGISLKNQKKIKKKSRT -------------------------------------------------------------- >81900_81900_14_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000399907_length(transcript)=3173nt_BP=231nt GGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAAGAATGCGGCCAAGACCA GGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCAGCTGGACAAAGCGTCCA TCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGAAAATGAGCCTGTTAATG TTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATTAACCTATGACATCCAGA GAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCTCTTTGGCCCTTCCCATA GCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACACCCCTCGGTGGACAACA AAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTATTACAACTGGAAAACAG TGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAATATTAAAATCAAAATCC GCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGTGATATTTGATTGTTCAC ATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTTCACAACCCTGGACTTAT TTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAACCCTCACGTGTCATCCA TCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGATGACAACTGAAGCGGCTC TGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCAGTGCCATAGACATAAGC CATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCACCTTTAATAAAACCAATG GCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGGCGAAGTGTCTAAACACTTGTATA AAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCACTGATT CATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATGGAAATG ACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCGATGGCA AATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTCCTCTTA CCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCAATGGTA CCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCTGTGTAC TCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACTT TACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAGTTGGAG GGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAATCCCCCA TAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGAAATCAA AAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCCAGAGAG TGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCGGGGGCC TCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCCAAGAAG AAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGGGAGTGG AAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAATCACGGA AGAATAATGATATTGAACAGGCTTTTTGTTTCTTTTATGGACTGCAATGTAAGCAAACCCATCCAACCAACTCCACTTCTGGAACTACTT TATCTACGGATTTAGAATGTGGTAAATTAATTCGAGAGGAGAGAGGGATTCGAAAACAGTCCTCAGTTCATACTGTGTAATCAGTTTAAA AAAAAAAAAAAAGATGTGCCCAGTAGAAAATGTTTTTGCTAATTGGTGTTGTTGATATTTGTATTTGCTAAGCATAAATAGCCACAATTC TCTATTCCTTTAGGATAGCAAAACTCATGTATTCTAGACATTGAAATGAATACACTGGAAAGATACTTGCACTGTATGTTGAAGCAGGGG CATATTAGGGGTATAAAGACTTCTAGAAATGTGTATTTACAGGAATCTTCTCTGTCCCACTCATCATCTTAGTTCTATCTTCATGCATTA >81900_81900_14_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000399907_length(amino acids)=937AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTD SNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELI DHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCN PDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVR DGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRD KITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQCKQ -------------------------------------------------------------- >81900_81900_15_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000399909_length(transcript)=3128nt_BP=231nt GGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAAGAATGCGGCCAAGACCA GGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCAGCTGGACAAAGCGTCCA TCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGAAAATGAGCCTGTTAATG TTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATTAACCTATGACATCCAGA GAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCTCTTTGGCCCTTCCCATA GCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACACCCCTCGGTGGACAACA AAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTATTACAACTGGAAAACAG TGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAATATTAAAATCAAAATCC GCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGTGATATTTGATTGTTCAC ATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTTCACAACCCTGGACTTAT TTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAACCCTCACGTGTCATCCA TCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGATGACAACTGAAGCGGCTC TGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCAGTGCCATAGACATAAGC CATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCACCTTTAATAAAACCAATG GCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGATTGGGATTTGGAATTCCAACAGTGGGCTTA ACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAAC CCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAA ACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTA AAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCT TCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATA TTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCC ACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAG GATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGG CCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATG GGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGC AGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTG AGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTC CTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATG GCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCC TTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAATCACGGAAGAATAATGATATTGAACAGGCTTTTTGTTTCTTTTATGGACTGC AATGTAAGCAAACCCATCCAACCAACTCCACTTCTGGAACTACTTTATCTACGGATTTAGAATGTGGTAAATTAATTCGAGAGGAGAGAG GGATTCGAAAACAGTCCTCAGTTCATACTGTGTAATCAGTTTAAAAAAAAAAAAAAAGATGTGCCCAGTAGAAAATGTTTTTGCTAATTG GTGTTGTTGATATTTGTATTTGCTAAGCATAAATAGCCACAATTCTCTATTCCTTTAGGATAGCAAAACTCATGTATTCTAGACATTGAA ATGAATACACTGGAAAGATACTTGCACTGTATGTTGAAGCAGGGGCATATTAGGGGTATAAAGACTTCTAGAAATGTGTATTTACAGGAA >81900_81900_15_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000399909_length(amino acids)=922AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLAN RTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITY VREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNS FWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKIST YEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKL HMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQCKQTHPTNSTSGTTLSTD -------------------------------------------------------------- >81900_81900_16_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000399913_length(transcript)=3173nt_BP=231nt GGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAAGAATGCGGCCAAGACCA GGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCAGCTGGACAAAGCGTCCA TCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGAAAATGAGCCTGTTAATG TTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATTAACCTATGACATCCAGA GAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCTCTTTGGCCCTTCCCATA GCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACACCCCTCGGTGGACAACA AAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTATTACAACTGGAAAACAG TGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAATATTAAAATCAAAATCC GCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGTGATATTTGATTGTTCAC ATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTTCACAACCCTGGACTTAT TTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAACCCTCACGTGTCATCCA TCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGATGACAACTGAAGCGGCTC TGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCAGTGCCATAGACATAAGC CATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCACCTTTAATAAAACCAATG GCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGGCGAAGTGTCTAAACACTTGTATA AAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCACTGATT CATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATGGAAATG ACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCGATGGCA AATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTCCTCTTA CCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCAATGGTA CCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCTGTGTAC TCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACTT TACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAGTTGGAG GGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAATCCCCCA TAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGAAATCAA AAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCCAGAGAG TGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCGGGGGCC TCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCCAAGAAG AAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGGGAGTGG AAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAATCACGGA AGAATAATGATATTGAACAGTGTCTCTCTTTCAACGCTATCATGGAAGAACTGGGAATCTCACTGAAGAATCAGAAAAAAATAAAGAAAA AGTCAAGAACTAAGGGGAAATCTTCCTTCACAAGTATCCTTACTTGTCATCAGAGACGAACTCAGAGAAAAGAGACTGTGGCGTGATCCA AGGAAACGCCTGTAGGAAGAAAAAGGATGCATTCCCTACAGATTTTTGGAGAAAGGATTTCTGAGGAGTGTGTGATGTGTTTCCATATAT CTATATCCATAACTCTGATTATGAATACAGATATAAGAAATACAAAAGTTTAAAAAGCTCACATAGATATGACTTGGGAAGTGACACCAG TTCTTTTAAAATAAATTTGTATGCTCAATTATTTTGCATTTTTTCTTTTTCCCCAATAAATTGTTGTGTGTGCTTTCTAAATAATAATAA >81900_81900_16_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000399913_length(amino acids)=939AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTD SNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELI DHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCN PDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVR DGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRD KITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQCLSFNAIMEELG -------------------------------------------------------------- >81900_81900_17_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000399914_length(transcript)=3215nt_BP=231nt GGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAAGAATGCGGCCAAGACCA GGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCAGCTGGACAAAGCGTCCA TCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGAAAATGAGCCTGTTAATG TTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATTAACCTATGACATCCAGA GAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCTCTTTGGCCCTTCCCATA GCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACACCCCTCGGTGGACAACA AAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTATTACAACTGGAAAACAG TGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAATATTAAAATCAAAATCC GCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGTGATATTTGATTGTTCAC ATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTTCACAACCCTGGACTTAT TTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAACCCTCACGTGTCATCCA TCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGATGACAACTGAAGCGGCTC TGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCAGTGCCATAGACATAAGC CATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCCCGGTGGGATGGCTTGACTGGGCATATCACCTTTAATAAAACCAATG GCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGATTGGGATTTGGAATTCCAACAGTGGGCTTA ACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCACTGATTCATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAAC CCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATGGAAATGACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAA ACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCGATGGCAAATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTA AAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTCCTCTTACCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCT TCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCAATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATA TTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCTGTGTACTCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCC ACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACTTTACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAG GATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAGTTGGAGGGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGG CCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAATCCCCCATAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATG GGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGAAATCAAAAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGC AGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCCAGAGAGTGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTG AGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCGGGGGCCTCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTC CTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCCAAGAAGAAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATG GCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGGGAGTGGAAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCC TTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAATCACGGAAGAATAATGATATTGAACAGAAAGGAAAGTCATCAAGAATTAGAT TTTATTTTAGGAACAAAGTAAGGTTTCATGGGAGAAAAAAACAAAGCCTTGGTGTAGAGAAGTGTCTCTCTTTCAACGCTATCATGGAAG AACTGGGAATCTCACTGAAGAATCAGAAAAAAATAAAGAAAAAGTCAAGAACTAAGGGGAAATCTTCCTTCACAAGTATCCTTACTTGTC ATCAGAGACGAACTCAGAGAAAAGAGACTGTGGCGTGATCCAAGGAAACGCCTGTAGGAAGAAAAAGGATGCATTCCCTACAGATTTTTG GAGAAAGGATTTCTGAGGAGTGTGTGATGTGTTTCCATATATCTATATCCATAACTCTGATTATGAATACAGATATAAGAAATACAAAAG TTTAAAAAGCTCACATAGATATGACTTGGGAAGTGACACCAGTTCTTTTAAAATAAATTTGTATGCTCAATTATTTTGCATTTTTTCTTT >81900_81900_17_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000399914_length(amino acids)=953AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLAN RTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITY VREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNS FWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKIST YEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKL HMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQKGKSSRIRFYFRNKVRFHGRKKQSLGV -------------------------------------------------------------- >81900_81900_18_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000535441_length(transcript)=2882nt_BP=231nt GGGGCTCCGCGGGCCTGGAGCACGGCCGGGTCTAATATGCCCGGAGCCGAGGCGCGATGAAGGAGAAGTCCAAGAATGCGGCCAAGACCA GGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCAGCTGGACAAAGCGTCCA TCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGAGGGATTTTTGAAACAGTGGAAAATGAGCCTGTTAATG TTGAAGAATTAGCTTTCAAGTTTGCAGTCACCAGCATTAACAGAAACCGAACCCTGATGCCTAACACCACATTAACCTATGACATCCAGA GAATTAACCTTTTTGATAGTTTTGAAGCCTCGCGGAGAGCATGTGACCAGCTGGCTCTTGGTGTGGCTGCTCTCTTTGGCCCTTCCCATA GCTCCTCCGTCAGTGCTGTGCAGTCTATTTGCAATGCTCTCGAAGTTCCACACATACAGACCCGCTGGAAACACCCCTCGGTGGACAACA AAGATTTGTTTTACATCAACCTTTACCCAGATTATGCAGCTATCAGCAGGGCGATCCTGGATCTGGTCCTCTATTACAACTGGAAAACAG TGACAGTGGTGTATGAAGACAGCACAGGTCTAATTCGTCTACAAGAGCTCATCAAAGCTCCCTCCAGATATAATATTAAAATCAAAATCC GCCAGCTGCCCTCTGGGAATAAAGATGCCAAGCCTTTACTCAAGGAGATGAAGAAAGGCAAGGAGTTCTATGTGATATTTGATTGTTCAC ATGAAACAGCCGCTGAAATCCTTAAGCAGATTCTGTTCATGGGCATGATGACCGAGTACTATCACTACTTTTTCACAACCCTGGACTTAT TTGCTTTGGATCTGGAACTCTATAGGTACAGTGGCGTAAACATGACCGGGTTTCGGCTGCTTAACATTGACAACCCTCACGTGTCATCCA TCATTGAGAAGTGGTCCATGGAGAGACTGCAGGCCCCACCCAGGCCCGAGACTGGCCTTTTGGATGGCATGATGACAACTGAAGCGGCTC TGATGTACGATGCTGTGTACATGGTGGCCATTGCCTCGCACCGGGCATCCCAGCTGACCGTCAGCTCCCTGCAGTGCCATAGACATAAGC CATGGCGCCTCGGACCCAGATTTATGAACCTGATCAAAGAGGCAACTGCCCGGTGGGATGGCTTGACTGGGCATATCACCTTTAATAAAA CCAATGGCTTGAGGAAGGATTTTGATCTGGACATTATTAGTCTCAAAGAGGAAGGAACTGAAAAGGCTGCTGGCGAAGTGTCTAAACACT TGTATAAAGTGTGGAAGAAGATTGGGATTTGGAATTCCAACAGTGGGCTTAACATGACGGACAGCAACAAAGACAAGTCCAGCAATATCA CTGATTCATTGGCCAACAGAACACTCATTGTCACCACCATTCTGGAAGAACCCTATGTTATGTACAGGAAATCTGATAAGCCTCTATATG GAAATGACAGATTTGAAGGATATTGCCTAGACCTGTTGAAAGAATTGTCAAACATCCTGGGTTTCATTTATGATGTTAAACTAGTTCCCG ATGGCAAATATGGGGCCCAGAATGACAAAGGGGAGTGGAACGGGATGGTTAAAGAACTCATAGATCACAGGGCTGACCTGGCAGTGGCTC CTCTTACCATCACCTACGTGCGGGAGAAAGTCATTGACTTCTCCAAACCCTTCATGACCCTAGGCATCAGCATTCTCTACCGGAAGCCCA ATGGTACCAATCCAGGCGTTTTCTCCTTCCTCAACCCCCTGTCTCCAGATATTTGGATGTATGTGCTCTTAGCCTGCTTGGGAGTCAGCT GTGTACTCTTTGTGATTGCAAGGTTTACACCCTACGAGTGGTATAACCCCCACCCATGCAACCCTGACTCAGACGTGGTGGAAAACAATT TTACTTTACTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGATCAGAGCTGATGCCCAAAGCTCTATCGACCAGAATAG TTGGAGGGATATGGTGGTTTTTCACCCTAATCATCATTTCATCCTACACGGCCAATCTGGCTGCCTTCTTGACAGTAGAGAGAATGGAAT CCCCCATAGATTCGGCAGATGATCTGGCAAAGCAAACCAAGATAGAATATGGGGCGGTTAGAGATGGATCAACAATGACCTTCTTCAAGA AATCAAAAATCTCCACCTATGAGAAGATGTGGGCTTTCATGAGCAGCAGGCAGCAGACCGCCCTGGTAAGAAACAGTGATGAGGGGATCC AGAGAGTGCTCACCACAGACTACGCGCTGCTGATGGAGTCCACCAGCATTGAGTATGTGACGCAGAGAAACTGCAACCTCACTCAGATCG GGGGCCTCATTGACTCCAAAGGTTACGGAGTGGGAACACCTATTGGTTCTCCTTACCGGGATAAAATTACTATTGCTATTCTTCAACTCC AAGAAGAAGGGAAGCTGCATATGATGAAAGAGAAGTGGTGGCGTGGGAATGGCTGCCCCGAGGAAGACAACAAAGAAGCCAGTGCCCTGG GAGTGGAAAATATTGGAGGCATCTTCATTGTTCTGGCTGCCGGACTGGTCCTTTCTGTATTTGTAGCTATTGGAGAATTCATATACAAAT CACGGAAGAATAATGATATTGAACAGTGTCTCTCTTTCAACGCTATCATGGAAGAACTGGGAATCTCACTGAAGAATCAGAAAAAAATAA AGAAAAAGTCAAGAACTAAGGGGAAATCTTCCTTCACAAGTATCCTTACTTGTCATCAGAGACGAACTCAGAGAAAAGAGACTGTGGCGT >81900_81900_18_SIM2-GRIK1_SIM2_chr21_38072221_ENST00000430056_GRIK1_chr21_31066382_ENST00000535441_length(amino acids)=942AA_BP=58 MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGGIFETVENEPVNVEELAFKFAVTSINRNRTL MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAI LDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTE YYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQL TVSSLQCHRHKPWRLGPRFMNLIKEATARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNM TDSNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKE LIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHP CNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGA VRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPY RDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQCLSFNAIMEE -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SIM2-GRIK1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SIM2-GRIK1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SIM2-GRIK1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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