FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:ATP6V1G1-TNC (FusionGDB2 ID:8200)

Fusion Gene Summary for ATP6V1G1-TNC

check button Fusion gene summary
Fusion gene informationFusion gene name: ATP6V1G1-TNC
Fusion gene ID: 8200
HgeneTgene
Gene symbol

ATP6V1G1

TNC

Gene ID

9550

7134

Gene nameATPase H+ transporting V1 subunit G1troponin C1, slow skeletal and cardiac type
SynonymsATP6G|ATP6G1|ATP6GL|ATP6J|Vma10CMD1Z|CMH13|TN-C|TNC|TNNC
Cytomap

9q32

3p21.1

Type of geneprotein-codingprotein-coding
DescriptionV-type proton ATPase subunit G 1ATPase, H+ transporting, lysosomal (vacuolar proton pump), member JATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1V-ATPase 13 kDa subunit 1V-ATPase subunit G 1vacuolar ATP synthase subunit M16vacuolar H(+)-ATPtroponin C, slow skeletal and cardiac musclescardiac troponin Cslow twitch skeletal/cardiac muscle troponin Ctroponin C type 1 (slow)
Modification date2020031320200313
UniProtAcc

O75348

.
Ensembl transtripts involved in fusion geneENST00000473413, ENST00000374050, 
ENST00000340094, ENST00000341037, 
ENST00000345230, ENST00000346706, 
ENST00000350763, ENST00000423613, 
ENST00000535648, ENST00000537320, 
ENST00000542877, ENST00000481475, 
Fusion gene scores* DoF score7 X 6 X 3=1268 X 8 X 4=256
# samples 711
** MAII scorelog2(7/126*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/256*10)=-1.21864028647534
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATP6V1G1 [Title/Abstract] AND TNC [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATP6V1G1(117350200)-TNC(117783546), # samples:1
Anticipated loss of major functional domain due to fusion event.ATP6V1G1-TNC seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ATP6V1G1-TNC seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ATP6V1G1-TNC seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTNC

GO:0006937

regulation of muscle contraction

18092822

TgeneTNC

GO:0060048

cardiac muscle contraction

25771144


check buttonFusion gene breakpoints across ATP6V1G1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TNC (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AO-A0JE-01AATP6V1G1chr9

117350200

+TNCchr9

117783546

-


Top

Fusion Gene ORF analysis for ATP6V1G1-TNC

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000473413ENST00000340094ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
3UTR-3CDSENST00000473413ENST00000341037ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
3UTR-3CDSENST00000473413ENST00000345230ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
3UTR-3CDSENST00000473413ENST00000346706ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
3UTR-3CDSENST00000473413ENST00000350763ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
3UTR-3CDSENST00000473413ENST00000423613ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
3UTR-3CDSENST00000473413ENST00000535648ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
3UTR-3CDSENST00000473413ENST00000537320ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
3UTR-3CDSENST00000473413ENST00000542877ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
3UTR-intronENST00000473413ENST00000481475ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
5CDS-intronENST00000374050ENST00000481475ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
Frame-shiftENST00000374050ENST00000340094ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
Frame-shiftENST00000374050ENST00000341037ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
Frame-shiftENST00000374050ENST00000345230ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
Frame-shiftENST00000374050ENST00000346706ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
Frame-shiftENST00000374050ENST00000350763ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
Frame-shiftENST00000374050ENST00000535648ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
Frame-shiftENST00000374050ENST00000537320ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
Frame-shiftENST00000374050ENST00000542877ATP6V1G1chr9

117350200

+TNCchr9

117783546

-
In-frameENST00000374050ENST00000423613ATP6V1G1chr9

117350200

+TNCchr9

117783546

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000374050ATP6V1G1chr9117350200+ENST00000423613TNCchr9117783546-4971757028571

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000374050ENST00000423613ATP6V1G1chr9117350200+TNCchr9117783546-0.437742650.5622574

Top

Fusion Genomic Features for ATP6V1G1-TNC


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for ATP6V1G1-TNC


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:117350200/chr9:117783546)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATP6V1G1

O75348

.
FUNCTION: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). {ECO:0000269|PubMed:28296633}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTNCchr9:117350200chr9:117783546ENST0000034009422241802_188818011838.0DomainFibronectin type-III 14
TgeneTNCchr9:117350200chr9:117783546ENST0000034009422241889_197718011838.0DomainFibronectin type-III 15
TgeneTNCchr9:117350200chr9:117783546ENST0000034009422241975_219018011838.0DomainFibrinogen C-terminal
TgeneTNCchr9:117350200chr9:117783546ENST0000034523019211533_162115281565.0DomainFibronectin type-III 11
TgeneTNCchr9:117350200chr9:117783546ENST0000034523019211622_171115281565.0DomainFibronectin type-III 12
TgeneTNCchr9:117350200chr9:117783546ENST0000034523019211712_180115281565.0DomainFibronectin type-III 13
TgeneTNCchr9:117350200chr9:117783546ENST0000034523019211802_188815281565.0DomainFibronectin type-III 14
TgeneTNCchr9:117350200chr9:117783546ENST0000034523019211889_197715281565.0DomainFibronectin type-III 15
TgeneTNCchr9:117350200chr9:117783546ENST0000034523019211975_219015281565.0DomainFibrinogen C-terminal
TgeneTNCchr9:117350200chr9:117783546ENST0000034670620221622_171116191656.0DomainFibronectin type-III 12
TgeneTNCchr9:117350200chr9:117783546ENST0000034670620221712_180116191656.0DomainFibronectin type-III 13
TgeneTNCchr9:117350200chr9:117783546ENST0000034670620221802_188816191656.0DomainFibronectin type-III 14
TgeneTNCchr9:117350200chr9:117783546ENST0000034670620221889_197716191656.0DomainFibronectin type-III 15
TgeneTNCchr9:117350200chr9:117783546ENST0000034670620221975_219016191656.0DomainFibrinogen C-terminal
TgeneTNCchr9:117350200chr9:117783546ENST0000053564821231712_180117101747.0DomainFibronectin type-III 13
TgeneTNCchr9:117350200chr9:117783546ENST0000053564821231802_188817101747.0DomainFibronectin type-III 14
TgeneTNCchr9:117350200chr9:117783546ENST0000053564821231889_197717101747.0DomainFibronectin type-III 15
TgeneTNCchr9:117350200chr9:117783546ENST0000053564821231975_219017101747.0DomainFibrinogen C-terminal
TgeneTNCchr9:117350200chr9:117783546ENST0000053732018201533_162115281565.0DomainFibronectin type-III 11
TgeneTNCchr9:117350200chr9:117783546ENST0000053732018201622_171115281565.0DomainFibronectin type-III 12
TgeneTNCchr9:117350200chr9:117783546ENST0000053732018201712_180115281565.0DomainFibronectin type-III 13
TgeneTNCchr9:117350200chr9:117783546ENST0000053732018201802_188815281565.0DomainFibronectin type-III 14
TgeneTNCchr9:117350200chr9:117783546ENST0000053732018201889_197715281565.0DomainFibronectin type-III 15
TgeneTNCchr9:117350200chr9:117783546ENST0000053732018201975_219015281565.0DomainFibrinogen C-terminal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224118_14518011838.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921118_14515281565.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022118_14516191656.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628118_14521652202.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123118_14517101747.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820118_14515281565.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr9:117350200chr9:117783546ENST0000034009422241076_116518011838.0DomainFibronectin type-III 6
TgeneTNCchr9:117350200chr9:117783546ENST0000034009422241167_125618011838.0DomainFibronectin type-III 7
TgeneTNCchr9:117350200chr9:117783546ENST0000034009422241258_135018011838.0DomainFibronectin type-III 8
TgeneTNCchr9:117350200chr9:117783546ENST0000034009422241351_143918011838.0DomainFibronectin type-III 9
TgeneTNCchr9:117350200chr9:117783546ENST0000034009422241440_153118011838.0DomainFibronectin type-III 10
TgeneTNCchr9:117350200chr9:117783546ENST0000034009422241533_162118011838.0DomainFibronectin type-III 11
TgeneTNCchr9:117350200chr9:117783546ENST0000034009422241622_171118011838.0DomainFibronectin type-III 12
TgeneTNCchr9:117350200chr9:117783546ENST0000034009422241712_180118011838.0DomainFibronectin type-III 13
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224174_18618011838.0DomainEGF-like 1%3B incomplete
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224186_21718011838.0DomainEGF-like 2
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224217_24818011838.0DomainEGF-like 3
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224248_28018011838.0DomainEGF-like 4
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224280_31118011838.0DomainEGF-like 5
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224311_34218011838.0DomainEGF-like 6
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224342_37318011838.0DomainEGF-like 7
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224373_40418011838.0DomainEGF-like 8
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224404_43518011838.0DomainEGF-like 9
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224435_46618011838.0DomainEGF-like 10
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224466_49718011838.0DomainEGF-like 11
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224497_52818011838.0DomainEGF-like 12
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224528_55918011838.0DomainEGF-like 13
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224559_59018011838.0DomainEGF-like 14
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224590_62118011838.0DomainEGF-like 15
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224625_71518011838.0DomainFibronectin type-III 1
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224716_80418011838.0DomainFibronectin type-III 2
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224805_89418011838.0DomainFibronectin type-III 3
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224895_99018011838.0DomainFibronectin type-III 4
TgeneTNCchr9:117350200chr9:117783546ENST000003400942224991_107518011838.0DomainFibronectin type-III 5
TgeneTNCchr9:117350200chr9:117783546ENST0000034523019211076_116515281565.0DomainFibronectin type-III 6
TgeneTNCchr9:117350200chr9:117783546ENST0000034523019211167_125615281565.0DomainFibronectin type-III 7
TgeneTNCchr9:117350200chr9:117783546ENST0000034523019211258_135015281565.0DomainFibronectin type-III 8
TgeneTNCchr9:117350200chr9:117783546ENST0000034523019211351_143915281565.0DomainFibronectin type-III 9
TgeneTNCchr9:117350200chr9:117783546ENST0000034523019211440_153115281565.0DomainFibronectin type-III 10
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921174_18615281565.0DomainEGF-like 1%3B incomplete
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921186_21715281565.0DomainEGF-like 2
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921217_24815281565.0DomainEGF-like 3
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921248_28015281565.0DomainEGF-like 4
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921280_31115281565.0DomainEGF-like 5
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921311_34215281565.0DomainEGF-like 6
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921342_37315281565.0DomainEGF-like 7
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921373_40415281565.0DomainEGF-like 8
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921404_43515281565.0DomainEGF-like 9
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921435_46615281565.0DomainEGF-like 10
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921466_49715281565.0DomainEGF-like 11
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921497_52815281565.0DomainEGF-like 12
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921528_55915281565.0DomainEGF-like 13
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921559_59015281565.0DomainEGF-like 14
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921590_62115281565.0DomainEGF-like 15
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921625_71515281565.0DomainFibronectin type-III 1
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921716_80415281565.0DomainFibronectin type-III 2
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921805_89415281565.0DomainFibronectin type-III 3
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921895_99015281565.0DomainFibronectin type-III 4
TgeneTNCchr9:117350200chr9:117783546ENST000003452301921991_107515281565.0DomainFibronectin type-III 5
TgeneTNCchr9:117350200chr9:117783546ENST0000034670620221076_116516191656.0DomainFibronectin type-III 6
TgeneTNCchr9:117350200chr9:117783546ENST0000034670620221167_125616191656.0DomainFibronectin type-III 7
TgeneTNCchr9:117350200chr9:117783546ENST0000034670620221258_135016191656.0DomainFibronectin type-III 8
TgeneTNCchr9:117350200chr9:117783546ENST0000034670620221351_143916191656.0DomainFibronectin type-III 9
TgeneTNCchr9:117350200chr9:117783546ENST0000034670620221440_153116191656.0DomainFibronectin type-III 10
TgeneTNCchr9:117350200chr9:117783546ENST0000034670620221533_162116191656.0DomainFibronectin type-III 11
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022174_18616191656.0DomainEGF-like 1%3B incomplete
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022186_21716191656.0DomainEGF-like 2
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022217_24816191656.0DomainEGF-like 3
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022248_28016191656.0DomainEGF-like 4
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022280_31116191656.0DomainEGF-like 5
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022311_34216191656.0DomainEGF-like 6
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022342_37316191656.0DomainEGF-like 7
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022373_40416191656.0DomainEGF-like 8
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022404_43516191656.0DomainEGF-like 9
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022435_46616191656.0DomainEGF-like 10
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022466_49716191656.0DomainEGF-like 11
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022497_52816191656.0DomainEGF-like 12
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022528_55916191656.0DomainEGF-like 13
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022559_59016191656.0DomainEGF-like 14
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022590_62116191656.0DomainEGF-like 15
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022625_71516191656.0DomainFibronectin type-III 1
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022716_80416191656.0DomainFibronectin type-III 2
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022805_89416191656.0DomainFibronectin type-III 3
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022895_99016191656.0DomainFibronectin type-III 4
TgeneTNCchr9:117350200chr9:117783546ENST000003467062022991_107516191656.0DomainFibronectin type-III 5
TgeneTNCchr9:117350200chr9:117783546ENST0000035076326281076_116521652202.0DomainFibronectin type-III 6
TgeneTNCchr9:117350200chr9:117783546ENST0000035076326281167_125621652202.0DomainFibronectin type-III 7
TgeneTNCchr9:117350200chr9:117783546ENST0000035076326281258_135021652202.0DomainFibronectin type-III 8
TgeneTNCchr9:117350200chr9:117783546ENST0000035076326281351_143921652202.0DomainFibronectin type-III 9
TgeneTNCchr9:117350200chr9:117783546ENST0000035076326281440_153121652202.0DomainFibronectin type-III 10
TgeneTNCchr9:117350200chr9:117783546ENST0000035076326281533_162121652202.0DomainFibronectin type-III 11
TgeneTNCchr9:117350200chr9:117783546ENST0000035076326281622_171121652202.0DomainFibronectin type-III 12
TgeneTNCchr9:117350200chr9:117783546ENST0000035076326281712_180121652202.0DomainFibronectin type-III 13
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628174_18621652202.0DomainEGF-like 1%3B incomplete
TgeneTNCchr9:117350200chr9:117783546ENST0000035076326281802_188821652202.0DomainFibronectin type-III 14
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628186_21721652202.0DomainEGF-like 2
TgeneTNCchr9:117350200chr9:117783546ENST0000035076326281889_197721652202.0DomainFibronectin type-III 15
TgeneTNCchr9:117350200chr9:117783546ENST0000035076326281975_219021652202.0DomainFibrinogen C-terminal
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628217_24821652202.0DomainEGF-like 3
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628248_28021652202.0DomainEGF-like 4
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628280_31121652202.0DomainEGF-like 5
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628311_34221652202.0DomainEGF-like 6
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628342_37321652202.0DomainEGF-like 7
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628373_40421652202.0DomainEGF-like 8
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628404_43521652202.0DomainEGF-like 9
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628435_46621652202.0DomainEGF-like 10
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628466_49721652202.0DomainEGF-like 11
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628497_52821652202.0DomainEGF-like 12
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628528_55921652202.0DomainEGF-like 13
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628559_59021652202.0DomainEGF-like 14
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628590_62121652202.0DomainEGF-like 15
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628625_71521652202.0DomainFibronectin type-III 1
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628716_80421652202.0DomainFibronectin type-III 2
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628805_89421652202.0DomainFibronectin type-III 3
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628895_99021652202.0DomainFibronectin type-III 4
TgeneTNCchr9:117350200chr9:117783546ENST000003507632628991_107521652202.0DomainFibronectin type-III 5
TgeneTNCchr9:117350200chr9:117783546ENST0000053564821231076_116517101747.0DomainFibronectin type-III 6
TgeneTNCchr9:117350200chr9:117783546ENST0000053564821231167_125617101747.0DomainFibronectin type-III 7
TgeneTNCchr9:117350200chr9:117783546ENST0000053564821231258_135017101747.0DomainFibronectin type-III 8
TgeneTNCchr9:117350200chr9:117783546ENST0000053564821231351_143917101747.0DomainFibronectin type-III 9
TgeneTNCchr9:117350200chr9:117783546ENST0000053564821231440_153117101747.0DomainFibronectin type-III 10
TgeneTNCchr9:117350200chr9:117783546ENST0000053564821231533_162117101747.0DomainFibronectin type-III 11
TgeneTNCchr9:117350200chr9:117783546ENST0000053564821231622_171117101747.0DomainFibronectin type-III 12
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123174_18617101747.0DomainEGF-like 1%3B incomplete
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123186_21717101747.0DomainEGF-like 2
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123217_24817101747.0DomainEGF-like 3
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123248_28017101747.0DomainEGF-like 4
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123280_31117101747.0DomainEGF-like 5
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123311_34217101747.0DomainEGF-like 6
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123342_37317101747.0DomainEGF-like 7
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123373_40417101747.0DomainEGF-like 8
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123404_43517101747.0DomainEGF-like 9
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123435_46617101747.0DomainEGF-like 10
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123466_49717101747.0DomainEGF-like 11
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123497_52817101747.0DomainEGF-like 12
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123528_55917101747.0DomainEGF-like 13
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123559_59017101747.0DomainEGF-like 14
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123590_62117101747.0DomainEGF-like 15
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123625_71517101747.0DomainFibronectin type-III 1
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123716_80417101747.0DomainFibronectin type-III 2
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123805_89417101747.0DomainFibronectin type-III 3
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123895_99017101747.0DomainFibronectin type-III 4
TgeneTNCchr9:117350200chr9:117783546ENST000005356482123991_107517101747.0DomainFibronectin type-III 5
TgeneTNCchr9:117350200chr9:117783546ENST0000053732018201076_116515281565.0DomainFibronectin type-III 6
TgeneTNCchr9:117350200chr9:117783546ENST0000053732018201167_125615281565.0DomainFibronectin type-III 7
TgeneTNCchr9:117350200chr9:117783546ENST0000053732018201258_135015281565.0DomainFibronectin type-III 8
TgeneTNCchr9:117350200chr9:117783546ENST0000053732018201351_143915281565.0DomainFibronectin type-III 9
TgeneTNCchr9:117350200chr9:117783546ENST0000053732018201440_153115281565.0DomainFibronectin type-III 10
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820174_18615281565.0DomainEGF-like 1%3B incomplete
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820186_21715281565.0DomainEGF-like 2
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820217_24815281565.0DomainEGF-like 3
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820248_28015281565.0DomainEGF-like 4
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820280_31115281565.0DomainEGF-like 5
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820311_34215281565.0DomainEGF-like 6
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820342_37315281565.0DomainEGF-like 7
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820373_40415281565.0DomainEGF-like 8
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820404_43515281565.0DomainEGF-like 9
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820435_46615281565.0DomainEGF-like 10
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820466_49715281565.0DomainEGF-like 11
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820497_52815281565.0DomainEGF-like 12
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820528_55915281565.0DomainEGF-like 13
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820559_59015281565.0DomainEGF-like 14
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820590_62115281565.0DomainEGF-like 15
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820625_71515281565.0DomainFibronectin type-III 1
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820716_80415281565.0DomainFibronectin type-III 2
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820805_89415281565.0DomainFibronectin type-III 3
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820895_99015281565.0DomainFibronectin type-III 4
TgeneTNCchr9:117350200chr9:117783546ENST000005373201820991_107515281565.0DomainFibronectin type-III 5


Top

Fusion Gene Sequence for ATP6V1G1-TNC


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8200_8200_1_ATP6V1G1-TNC_ATP6V1G1_chr9_117350200_ENST00000374050_TNC_chr9_117783546_ENST00000423613_length(transcript)=497nt_BP=175nt
GCAAGCGCAGATTGTGGGCGGCTGTGTCAGCTGACCCAAGGGGCCTTCGAGGTGCCTTAGGCCGCTTGCCTTGCTCTCAGAATCGCTGCC
GCCATGGCTAGTCAGTCTCAGGGGATTCAGCAGCTGCTGCAGGCCGAGAAGCGGGCAGCCGAGAAGGTGTCCGAGGCCCGCAAAAGGCGT
TAACTGGTTCCACTGGAAGGGCCACGAACACTCAATCCAGTTTGCTGAGATGAAGCTGAGACCAAGCAACTTCAGAAATCTTGAAGGCAG
GCGCAAACGGGCATAAATTCCAGGGACCACTGGGTGAGAGAGGAATAAGGCCCAGAGCGAGGAAAGGATTTTACCAAAGCATCAATACAA
CCAGCCCAACCATCGGTCCACACCTGGGCATTTGGTGAGAGTCAAAGCTGACCATGGATCCCTGGGGCCAACGGCAACAGCATGGGCCTC

>8200_8200_1_ATP6V1G1-TNC_ATP6V1G1_chr9_117350200_ENST00000374050_TNC_chr9_117783546_ENST00000423613_length(amino acids)=71AA_BP=35

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ATP6V1G1-TNC


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for ATP6V1G1-TNC


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for ATP6V1G1-TNC


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource