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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SKA2-HEATR6 (FusionGDB2 ID:82033) |
Fusion Gene Summary for SKA2-HEATR6 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SKA2-HEATR6 | Fusion gene ID: 82033 | Hgene | Tgene | Gene symbol | SKA2 | HEATR6 | Gene ID | 348235 | 63897 |
| Gene name | spindle and kinetochore associated complex subunit 2 | HEAT repeat containing 6 | |
| Synonyms | FAM33A | ABC1 | |
| Cytomap | 17q22 | 17q23.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | spindle and kinetochore-associated protein 2family with sequence similarity 33, member Aspindle and KT (kinetochore) associated 2 | HEAT repeat-containing protein 6amplified in breast cancer 1amplified in breast cancer protein 1 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | Q6AI08 | |
| Ensembl transtripts involved in fusion gene | ENST00000330137, ENST00000437036, ENST00000578105, ENST00000580541, ENST00000581068, ENST00000583380, ENST00000583927, | ENST00000585712, ENST00000184956, ENST00000585976, | |
| Fusion gene scores | * DoF score | 13 X 10 X 5=650 | 11 X 10 X 6=660 |
| # samples | 14 | 12 | |
| ** MAII score | log2(14/650*10)=-2.21501289097085 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/660*10)=-2.4594316186373 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SKA2 [Title/Abstract] AND HEATR6 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SKA2(57232317)-HEATR6(58137457), # samples:1 SKA2(57232491)-HEATR6(58137457), # samples:1 SKA2(57232492)-HEATR6(58137457), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SKA2 | GO:0031110 | regulation of microtubule polymerization or depolymerization | 19289083 |
| Fusion gene breakpoints across SKA2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across HEATR6 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SARC | TCGA-DX-A3M1-01A | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| ChimerDB4 | SARC | TCGA-DX-A3M1-01A | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| ChimerDB4 | SARC | TCGA-DX-A3M1 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
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Fusion Gene ORF analysis for SKA2-HEATR6 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000330137 | ENST00000585712 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| 5CDS-intron | ENST00000330137 | ENST00000585712 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| 5CDS-intron | ENST00000437036 | ENST00000585712 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| 5CDS-intron | ENST00000578105 | ENST00000585712 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| 5CDS-intron | ENST00000578105 | ENST00000585712 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| 5CDS-intron | ENST00000580541 | ENST00000585712 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| 5CDS-intron | ENST00000581068 | ENST00000585712 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| 5CDS-intron | ENST00000581068 | ENST00000585712 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| 5CDS-intron | ENST00000583380 | ENST00000585712 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| 5CDS-intron | ENST00000583380 | ENST00000585712 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| 5UTR-3CDS | ENST00000583927 | ENST00000184956 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| 5UTR-3CDS | ENST00000583927 | ENST00000184956 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| 5UTR-3CDS | ENST00000583927 | ENST00000585976 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| 5UTR-3CDS | ENST00000583927 | ENST00000585976 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| 5UTR-intron | ENST00000583927 | ENST00000585712 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| 5UTR-intron | ENST00000583927 | ENST00000585712 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000330137 | ENST00000184956 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000330137 | ENST00000184956 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000330137 | ENST00000585976 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000330137 | ENST00000585976 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000437036 | ENST00000184956 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000437036 | ENST00000585976 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000578105 | ENST00000184956 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000578105 | ENST00000184956 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000578105 | ENST00000585976 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000578105 | ENST00000585976 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000580541 | ENST00000184956 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000580541 | ENST00000585976 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000581068 | ENST00000184956 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000581068 | ENST00000184956 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000581068 | ENST00000585976 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000581068 | ENST00000585976 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000583380 | ENST00000184956 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000583380 | ENST00000184956 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000583380 | ENST00000585976 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| In-frame | ENST00000583380 | ENST00000585976 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000330137 | ENST00000184956 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000330137 | ENST00000585976 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000437036 | ENST00000184956 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000437036 | ENST00000184956 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000437036 | ENST00000585976 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000437036 | ENST00000585976 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000578105 | ENST00000184956 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000578105 | ENST00000585976 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000580541 | ENST00000184956 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000580541 | ENST00000184956 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000580541 | ENST00000585976 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000580541 | ENST00000585976 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000581068 | ENST00000184956 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000581068 | ENST00000585976 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000583380 | ENST00000184956 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000583380 | ENST00000585976 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000583927 | ENST00000184956 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-3CDS | ENST00000583927 | ENST00000585976 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-intron | ENST00000330137 | ENST00000585712 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-intron | ENST00000437036 | ENST00000585712 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| intron-intron | ENST00000437036 | ENST00000585712 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| intron-intron | ENST00000578105 | ENST00000585712 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-intron | ENST00000580541 | ENST00000585712 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - |
| intron-intron | ENST00000580541 | ENST00000585712 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - |
| intron-intron | ENST00000581068 | ENST00000585712 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-intron | ENST00000583380 | ENST00000585712 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| intron-intron | ENST00000583927 | ENST00000585712 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000580541 | SKA2 | chr17 | 57232317 | - | ENST00000184956 | HEATR6 | chr17 | 58137457 | - | 2728 | 229 | 79 | 2358 | 759 |
| ENST00000580541 | SKA2 | chr17 | 57232317 | - | ENST00000585976 | HEATR6 | chr17 | 58137457 | - | 2094 | 229 | 79 | 2022 | 647 |
| ENST00000437036 | SKA2 | chr17 | 57232317 | - | ENST00000184956 | HEATR6 | chr17 | 58137457 | - | 2738 | 239 | 89 | 2368 | 759 |
| ENST00000437036 | SKA2 | chr17 | 57232317 | - | ENST00000585976 | HEATR6 | chr17 | 58137457 | - | 2104 | 239 | 89 | 2032 | 647 |
| ENST00000330137 | SKA2 | chr17 | 57232491 | - | ENST00000184956 | HEATR6 | chr17 | 58137457 | - | 2638 | 139 | 106 | 2268 | 720 |
| ENST00000330137 | SKA2 | chr17 | 57232491 | - | ENST00000585976 | HEATR6 | chr17 | 58137457 | - | 2004 | 139 | 106 | 1932 | 608 |
| ENST00000578105 | SKA2 | chr17 | 57232491 | - | ENST00000184956 | HEATR6 | chr17 | 58137457 | - | 2553 | 54 | 21 | 2183 | 720 |
| ENST00000578105 | SKA2 | chr17 | 57232491 | - | ENST00000585976 | HEATR6 | chr17 | 58137457 | - | 1919 | 54 | 21 | 1847 | 608 |
| ENST00000581068 | SKA2 | chr17 | 57232491 | - | ENST00000184956 | HEATR6 | chr17 | 58137457 | - | 2617 | 118 | 85 | 2247 | 720 |
| ENST00000581068 | SKA2 | chr17 | 57232491 | - | ENST00000585976 | HEATR6 | chr17 | 58137457 | - | 1983 | 118 | 85 | 1911 | 608 |
| ENST00000583380 | SKA2 | chr17 | 57232491 | - | ENST00000184956 | HEATR6 | chr17 | 58137457 | - | 2543 | 44 | 11 | 2173 | 720 |
| ENST00000583380 | SKA2 | chr17 | 57232491 | - | ENST00000585976 | HEATR6 | chr17 | 58137457 | - | 1909 | 44 | 11 | 1837 | 608 |
| ENST00000330137 | SKA2 | chr17 | 57232492 | - | ENST00000184956 | HEATR6 | chr17 | 58137457 | - | 2638 | 139 | 106 | 2268 | 720 |
| ENST00000330137 | SKA2 | chr17 | 57232492 | - | ENST00000585976 | HEATR6 | chr17 | 58137457 | - | 2004 | 139 | 106 | 1932 | 608 |
| ENST00000578105 | SKA2 | chr17 | 57232492 | - | ENST00000184956 | HEATR6 | chr17 | 58137457 | - | 2553 | 54 | 21 | 2183 | 720 |
| ENST00000578105 | SKA2 | chr17 | 57232492 | - | ENST00000585976 | HEATR6 | chr17 | 58137457 | - | 1919 | 54 | 21 | 1847 | 608 |
| ENST00000581068 | SKA2 | chr17 | 57232492 | - | ENST00000184956 | HEATR6 | chr17 | 58137457 | - | 2617 | 118 | 85 | 2247 | 720 |
| ENST00000581068 | SKA2 | chr17 | 57232492 | - | ENST00000585976 | HEATR6 | chr17 | 58137457 | - | 1983 | 118 | 85 | 1911 | 608 |
| ENST00000583380 | SKA2 | chr17 | 57232492 | - | ENST00000184956 | HEATR6 | chr17 | 58137457 | - | 2543 | 44 | 11 | 2173 | 720 |
| ENST00000583380 | SKA2 | chr17 | 57232492 | - | ENST00000585976 | HEATR6 | chr17 | 58137457 | - | 1909 | 44 | 11 | 1837 | 608 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000580541 | ENST00000184956 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - | 0.005469174 | 0.99453086 |
| ENST00000580541 | ENST00000585976 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - | 0.008180525 | 0.9918195 |
| ENST00000437036 | ENST00000184956 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - | 0.005435038 | 0.9945649 |
| ENST00000437036 | ENST00000585976 | SKA2 | chr17 | 57232317 | - | HEATR6 | chr17 | 58137457 | - | 0.008111094 | 0.99188894 |
| ENST00000330137 | ENST00000184956 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - | 0.002289119 | 0.9977108 |
| ENST00000330137 | ENST00000585976 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - | 0.003559738 | 0.99644023 |
| ENST00000578105 | ENST00000184956 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - | 0.00228555 | 0.9977144 |
| ENST00000578105 | ENST00000585976 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - | 0.003643826 | 0.99635625 |
| ENST00000581068 | ENST00000184956 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - | 0.002371061 | 0.997629 |
| ENST00000581068 | ENST00000585976 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - | 0.003693278 | 0.9963068 |
| ENST00000583380 | ENST00000184956 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - | 0.002351534 | 0.9976484 |
| ENST00000583380 | ENST00000585976 | SKA2 | chr17 | 57232491 | - | HEATR6 | chr17 | 58137457 | - | 0.003772979 | 0.996227 |
| ENST00000330137 | ENST00000184956 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - | 0.002289119 | 0.9977108 |
| ENST00000330137 | ENST00000585976 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - | 0.003559738 | 0.99644023 |
| ENST00000578105 | ENST00000184956 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - | 0.00228555 | 0.9977144 |
| ENST00000578105 | ENST00000585976 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - | 0.003643826 | 0.99635625 |
| ENST00000581068 | ENST00000184956 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - | 0.002371061 | 0.997629 |
| ENST00000581068 | ENST00000585976 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - | 0.003693278 | 0.9963068 |
| ENST00000583380 | ENST00000184956 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - | 0.002351534 | 0.9976484 |
| ENST00000583380 | ENST00000585976 | SKA2 | chr17 | 57232492 | - | HEATR6 | chr17 | 58137457 | - | 0.003772979 | 0.996227 |
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Fusion Genomic Features for SKA2-HEATR6 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SKA2-HEATR6 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:57232317/chr17:58137457) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | HEATR6 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Amplification-dependent oncogene. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | HEATR6 | chr17:57232317 | chr17:58137457 | ENST00000184956 | 8 | 20 | 515_552 | 472 | 1182.0 | Repeat | Note=HEAT 3 | |
| Tgene | HEATR6 | chr17:57232317 | chr17:58137457 | ENST00000184956 | 8 | 20 | 558_595 | 472 | 1182.0 | Repeat | Note=HEAT 4 | |
| Tgene | HEATR6 | chr17:57232491 | chr17:58137457 | ENST00000184956 | 8 | 20 | 515_552 | 472 | 1182.0 | Repeat | Note=HEAT 3 | |
| Tgene | HEATR6 | chr17:57232491 | chr17:58137457 | ENST00000184956 | 8 | 20 | 558_595 | 472 | 1182.0 | Repeat | Note=HEAT 4 | |
| Tgene | HEATR6 | chr17:57232492 | chr17:58137457 | ENST00000184956 | 8 | 20 | 515_552 | 472 | 1182.0 | Repeat | Note=HEAT 3 | |
| Tgene | HEATR6 | chr17:57232492 | chr17:58137457 | ENST00000184956 | 8 | 20 | 558_595 | 472 | 1182.0 | Repeat | Note=HEAT 4 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | HEATR6 | chr17:57232317 | chr17:58137457 | ENST00000184956 | 8 | 20 | 315_325 | 472 | 1182.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | HEATR6 | chr17:57232317 | chr17:58137457 | ENST00000184956 | 8 | 20 | 330_335 | 472 | 1182.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | HEATR6 | chr17:57232317 | chr17:58137457 | ENST00000184956 | 8 | 20 | 383_390 | 472 | 1182.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | HEATR6 | chr17:57232491 | chr17:58137457 | ENST00000184956 | 8 | 20 | 315_325 | 472 | 1182.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | HEATR6 | chr17:57232491 | chr17:58137457 | ENST00000184956 | 8 | 20 | 330_335 | 472 | 1182.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | HEATR6 | chr17:57232491 | chr17:58137457 | ENST00000184956 | 8 | 20 | 383_390 | 472 | 1182.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | HEATR6 | chr17:57232492 | chr17:58137457 | ENST00000184956 | 8 | 20 | 315_325 | 472 | 1182.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | HEATR6 | chr17:57232492 | chr17:58137457 | ENST00000184956 | 8 | 20 | 330_335 | 472 | 1182.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | HEATR6 | chr17:57232492 | chr17:58137457 | ENST00000184956 | 8 | 20 | 383_390 | 472 | 1182.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | HEATR6 | chr17:57232317 | chr17:58137457 | ENST00000184956 | 8 | 20 | 159_198 | 472 | 1182.0 | Repeat | Note=HEAT 1 | |
| Tgene | HEATR6 | chr17:57232317 | chr17:58137457 | ENST00000184956 | 8 | 20 | 452_490 | 472 | 1182.0 | Repeat | Note=HEAT 2 | |
| Tgene | HEATR6 | chr17:57232491 | chr17:58137457 | ENST00000184956 | 8 | 20 | 159_198 | 472 | 1182.0 | Repeat | Note=HEAT 1 | |
| Tgene | HEATR6 | chr17:57232491 | chr17:58137457 | ENST00000184956 | 8 | 20 | 452_490 | 472 | 1182.0 | Repeat | Note=HEAT 2 | |
| Tgene | HEATR6 | chr17:57232492 | chr17:58137457 | ENST00000184956 | 8 | 20 | 159_198 | 472 | 1182.0 | Repeat | Note=HEAT 1 | |
| Tgene | HEATR6 | chr17:57232492 | chr17:58137457 | ENST00000184956 | 8 | 20 | 452_490 | 472 | 1182.0 | Repeat | Note=HEAT 2 |
Top |
Fusion Gene Sequence for SKA2-HEATR6 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >82033_82033_1_SKA2-HEATR6_SKA2_chr17_57232317_ENST00000437036_HEATR6_chr17_58137457_ENST00000184956_length(transcript)=2738nt_BP=239nt GCCGCGGTCTGCGGAATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGGTGAGTGCAAAGTGAAGGAGATCTAC TGGGTAGTTTATTTTTCCCCCATGGCCTCGGAGGTGGGGCACAATTTGGAGTCGCCGGAAACTCCGGGCGGCGGAGGCTGGACCAGAGTC GAGTTCCCTCCTCCTGCACCAAAGGGAGCCGCCACCGTCTGGTGTCTAAACCGCCTCGGACACGTGCCTGTGCTCTGCAAGTTTTATCTG CCATCTTGGAAGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCG CTTGCAGCATTAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCC TTGCAAATTTAGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCC ACAAAGATGTTAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTC TGCAACAGCCATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAG GACCCTCTCTGGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTAC TGCCCAAGGAGGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTAC AGGTATTGACTCTTCTGGCAAGGGGCTACTTTTCAATGACTCAAGCCTACTTGATGGAGCTTGGAGAGGTGATTTGCAAGTGCATGGGGG AAGCAGATCCATCCATTCAGCTTCATGGAGCAAAGCTTCTGGAAGAACTGGGCACAGGCTTAATACAGCAGTATAAACCAGACTCCACTG CAGCACCTGATCAGAGAGCACCAGTCTTCTTGGTGGTGATGTTCTGGACTATGATGCTGAACGGTCCTTTACCCAGAGCCCTGCAGAATT CAGAACACCCAACTCTCCAGGCGAGCGCCTGTGATGCCCTGTCTTCCATCTTGCCAGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGA TGCTGTGCATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGC TTTTTCCCTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTC GAGCCAAAGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCT CTGGTCTCCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTG GAAATTTGCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTA CTGTTCTAACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGA CAGCCCCATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTG CCCTTTCCGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGA GTGAAGACACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGG CCAGTGCCTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAG GAGCAGAGGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCC AGGCACCAACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAG GGGCACTCCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATA AGATCTGTGGGATTTCATCTTAGGGGCAGAAACAATCCGTTCACTATTTATTTAGAATGACTTAGCAGCCATTTAAATTTTCACAGAGGG CTCAACCACCTTTGGAGTGACTCCATAGCACTGGCCATGGTCAGGGTTGTTGGAACATCTGACCTGTGCATCCAGGAGCCGAGGAGTCAG GTTGTAATACAGGCCAAGCAGACGGGCTTTGAGGGCATTTAGTCTCAGAAAAAAAAAATGTAGAAGGATTTCGGAATTAGAATTTTGTGT >82033_82033_1_SKA2-HEATR6_SKA2_chr17_57232317_ENST00000437036_HEATR6_chr17_58137457_ENST00000184956_length(amino acids)=759AA_BP=50 MGSLFFPHGLGGGAQFGVAGNSGRRRLDQSRVPSSCTKGSRHRLVSKPPRTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMI ACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAPYDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLL LQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSVSSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAL QVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLHGAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQN SEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNV RAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALIS TVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQK SEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSI -------------------------------------------------------------- >82033_82033_2_SKA2-HEATR6_SKA2_chr17_57232317_ENST00000437036_HEATR6_chr17_58137457_ENST00000585976_length(transcript)=2104nt_BP=239nt GCCGCGGTCTGCGGAATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGGTGAGTGCAAAGTGAAGGAGATCTAC TGGGTAGTTTATTTTTCCCCCATGGCCTCGGAGGTGGGGCACAATTTGGAGTCGCCGGAAACTCCGGGCGGCGGAGGCTGGACCAGAGTC GAGTTCCCTCCTCCTGCACCAAAGGGAGCCGCCACCGTCTGGTGTCTAAACCGCCTCGGACACGTGCCTGTGCTCTGCAAGTTTTATCTG CCATCTTGGAAGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCG CTTGCAGCATTAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCC TTGCAAATTTAGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCC ACAAAGATGTTAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTC TGCAACAGCCATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAG GACCCTCTCTGGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTAC TGCCCAAGGAGGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTCA GCAATCTGCCGAATGACAGGCAGATGCTGTGCATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTT CACGGGCCCTGGGAGTCTATGTGCTTTTTCCCTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCAC TTGAAGACAAGTCTCTGAATGTTCGAGCCAAAGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAG ACCCAAGTTTCCAGGAAGAGTTCTCTGGTCTCCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAA AAAGCAATGCAGTCCGGGCCCTTGGAAATTTGCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGG AGTCTATCCAGGCCCTAATTTCTACTGTTCTAACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTA AAAATCCTGCCCTTCCTTTAGGGACAGCCCCATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCA AAGTGCGCATCAGATCTGCAGCTGCCCTTTCCGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATG CATTGGTCACCGCTTTACAGAAGAGTGAAGACACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGG CACTGATTCACCTCTTGAGCTTGGCCAGTGCCTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCT ATATTCTACAGTTTTTAAAATCAGGAGCAGAGGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGG CCCTTAAACACATGGGCAGCATCCAGGCACCAACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTT GTTTTGACTCATCTGGATCACAAGGGGCACTCCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAG >82033_82033_2_SKA2-HEATR6_SKA2_chr17_57232317_ENST00000437036_HEATR6_chr17_58137457_ENST00000585976_length(amino acids)=647AA_BP=50 MGSLFFPHGLGGGAQFGVAGNSGRRRLDQSRVPSSCTKGSRHRLVSKPPRTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMI ACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAPYDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLL LQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSVSSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAF SNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETP DPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVF KNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQ ALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAV -------------------------------------------------------------- >82033_82033_3_SKA2-HEATR6_SKA2_chr17_57232317_ENST00000580541_HEATR6_chr17_58137457_ENST00000184956_length(transcript)=2728nt_BP=229nt GCGGAATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGGTGAGTGCAAAGTGAAGGAGATCTACTGGGTAGTTT ATTTTTCCCCCATGGCCTCGGAGGTGGGGCACAATTTGGAGTCGCCGGAAACTCCGGGCGGCGGAGGCTGGACCAGAGTCGAGTTCCCTC CTCCTGCACCAAAGGGAGCCGCCACCGTCTGGTGTCTAAACCGCCTCGGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGA AGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCAT TAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTT AGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGT TAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCC ATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCT GGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGA GGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTACAGGTATTGAC TCTTCTGGCAAGGGGCTACTTTTCAATGACTCAAGCCTACTTGATGGAGCTTGGAGAGGTGATTTGCAAGTGCATGGGGGAAGCAGATCC ATCCATTCAGCTTCATGGAGCAAAGCTTCTGGAAGAACTGGGCACAGGCTTAATACAGCAGTATAAACCAGACTCCACTGCAGCACCTGA TCAGAGAGCACCAGTCTTCTTGGTGGTGATGTTCTGGACTATGATGCTGAACGGTCCTTTACCCAGAGCCCTGCAGAATTCAGAACACCC AACTCTCCAGGCGAGCGCCTGTGATGCCCTGTCTTCCATCTTGCCAGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGATGCTGTGCAT CACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGCTTTTTCCCTG TCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTCGAGCCAAAGC AGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCTCTGGTCTCCT GCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTGGAAATTTGCT TCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTACTGTTCTAAC AGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGACAGCCCCATG GACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTGCCCTTTCCGT CCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGAGTGAAGACAC CATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGGCCAGTGCCTC GGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAGGAGCAGAGGG AGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCCAGGCACCAAC TGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAGGGGCACTCCC AGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATAAGATCTGTGG GATTTCATCTTAGGGGCAGAAACAATCCGTTCACTATTTATTTAGAATGACTTAGCAGCCATTTAAATTTTCACAGAGGGCTCAACCACC TTTGGAGTGACTCCATAGCACTGGCCATGGTCAGGGTTGTTGGAACATCTGACCTGTGCATCCAGGAGCCGAGGAGTCAGGTTGTAATAC AGGCCAAGCAGACGGGCTTTGAGGGCATTTAGTCTCAGAAAAAAAAAATGTAGAAGGATTTCGGAATTAGAATTTTGTGTATTGTATCTG >82033_82033_3_SKA2-HEATR6_SKA2_chr17_57232317_ENST00000580541_HEATR6_chr17_58137457_ENST00000184956_length(amino acids)=759AA_BP=50 MGSLFFPHGLGGGAQFGVAGNSGRRRLDQSRVPSSCTKGSRHRLVSKPPRTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMI ACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAPYDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLL LQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSVSSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAL QVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLHGAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQN SEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNV RAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALIS TVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQK SEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSI -------------------------------------------------------------- >82033_82033_4_SKA2-HEATR6_SKA2_chr17_57232317_ENST00000580541_HEATR6_chr17_58137457_ENST00000585976_length(transcript)=2094nt_BP=229nt GCGGAATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGGTGAGTGCAAAGTGAAGGAGATCTACTGGGTAGTTT ATTTTTCCCCCATGGCCTCGGAGGTGGGGCACAATTTGGAGTCGCCGGAAACTCCGGGCGGCGGAGGCTGGACCAGAGTCGAGTTCCCTC CTCCTGCACCAAAGGGAGCCGCCACCGTCTGGTGTCTAAACCGCCTCGGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGA AGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCAT TAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTT AGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGT TAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCC ATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCT GGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGA GGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTCAGCAATCTGCC GAATGACAGGCAGATGCTGTGCATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCT GGGAGTCTATGTGCTTTTTCCCTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAA GTCTCTGAATGTTCGAGCCAAAGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTT CCAGGAAGAGTTCTCTGGTCTCCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGC AGTCCGGGCCCTTGGAAATTTGCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCA GGCCCTAATTTCTACTGTTCTAACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGC CCTTCCTTTAGGGACAGCCCCATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCAT CAGATCTGCAGCTGCCCTTTCCGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCAC CGCTTTACAGAAGAGTGAAGACACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCA CCTCTTGAGCTTGGCCAGTGCCTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACA GTTTTTAAAATCAGGAGCAGAGGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACA CATGGGCAGCATCCAGGCACCAACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTC ATCTGGATCACAAGGGGCACTCCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACC >82033_82033_4_SKA2-HEATR6_SKA2_chr17_57232317_ENST00000580541_HEATR6_chr17_58137457_ENST00000585976_length(amino acids)=647AA_BP=50 MGSLFFPHGLGGGAQFGVAGNSGRRRLDQSRVPSSCTKGSRHRLVSKPPRTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMI ACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAPYDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLL LQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSVSSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAF SNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETP DPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVF KNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQ ALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAV -------------------------------------------------------------- >82033_82033_5_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000330137_HEATR6_chr17_58137457_ENST00000184956_length(transcript)=2638nt_BP=139nt AATGAGTGCGAGATGTTGAGTGACAGCTGTCCAATGGAGGCCCTCCGTGCTAGTACGGCTTGCGGCTTAAGCGCCGCCGCGGTCTGCGGA ATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGA AGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCAT TAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTT AGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGT TAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCC ATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCT GGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGA GGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTACAGGTATTGAC TCTTCTGGCAAGGGGCTACTTTTCAATGACTCAAGCCTACTTGATGGAGCTTGGAGAGGTGATTTGCAAGTGCATGGGGGAAGCAGATCC ATCCATTCAGCTTCATGGAGCAAAGCTTCTGGAAGAACTGGGCACAGGCTTAATACAGCAGTATAAACCAGACTCCACTGCAGCACCTGA TCAGAGAGCACCAGTCTTCTTGGTGGTGATGTTCTGGACTATGATGCTGAACGGTCCTTTACCCAGAGCCCTGCAGAATTCAGAACACCC AACTCTCCAGGCGAGCGCCTGTGATGCCCTGTCTTCCATCTTGCCAGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGATGCTGTGCAT CACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGCTTTTTCCCTG TCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTCGAGCCAAAGC AGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCTCTGGTCTCCT GCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTGGAAATTTGCT TCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTACTGTTCTAAC AGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGACAGCCCCATG GACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTGCCCTTTCCGT CCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGAGTGAAGACAC CATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGGCCAGTGCCTC GGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAGGAGCAGAGGG AGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCCAGGCACCAAC TGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAGGGGCACTCCC AGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATAAGATCTGTGG GATTTCATCTTAGGGGCAGAAACAATCCGTTCACTATTTATTTAGAATGACTTAGCAGCCATTTAAATTTTCACAGAGGGCTCAACCACC TTTGGAGTGACTCCATAGCACTGGCCATGGTCAGGGTTGTTGGAACATCTGACCTGTGCATCCAGGAGCCGAGGAGTCAGGTTGTAATAC AGGCCAAGCAGACGGGCTTTGAGGGCATTTAGTCTCAGAAAAAAAAAATGTAGAAGGATTTCGGAATTAGAATTTTGTGTATTGTATCTG >82033_82033_5_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000330137_HEATR6_chr17_58137457_ENST00000184956_length(amino acids)=720AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLH GAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLG LNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKML RSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAY NALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCM KETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ -------------------------------------------------------------- >82033_82033_6_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000330137_HEATR6_chr17_58137457_ENST00000585976_length(transcript)=2004nt_BP=139nt AATGAGTGCGAGATGTTGAGTGACAGCTGTCCAATGGAGGCCCTCCGTGCTAGTACGGCTTGCGGCTTAAGCGCCGCCGCGGTCTGCGGA ATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGA AGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCAT TAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTT AGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGT TAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCC ATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCT GGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGA GGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTCAGCAATCTGCC GAATGACAGGCAGATGCTGTGCATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCT GGGAGTCTATGTGCTTTTTCCCTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAA GTCTCTGAATGTTCGAGCCAAAGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTT CCAGGAAGAGTTCTCTGGTCTCCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGC AGTCCGGGCCCTTGGAAATTTGCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCA GGCCCTAATTTCTACTGTTCTAACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGC CCTTCCTTTAGGGACAGCCCCATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCAT CAGATCTGCAGCTGCCCTTTCCGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCAC CGCTTTACAGAAGAGTGAAGACACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCA CCTCTTGAGCTTGGCCAGTGCCTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACA GTTTTTAAAATCAGGAGCAGAGGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACA CATGGGCAGCATCCAGGCACCAACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTC ATCTGGATCACAAGGGGCACTCCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACC >82033_82033_6_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000330137_HEATR6_chr17_58137457_ENST00000585976_length(amino acids)=608AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVL FPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALG NLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAA LSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSG -------------------------------------------------------------- >82033_82033_7_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000578105_HEATR6_chr17_58137457_ENST00000184956_length(transcript)=2553nt_BP=54nt GCGGAATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATC TTGGAAGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGC AGCATTAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCA AATTTAGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAA GATGTTAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAA CAGCCATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCC TCTCTGGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCC AAGGAGGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTACAGGTA TTGACTCTTCTGGCAAGGGGCTACTTTTCAATGACTCAAGCCTACTTGATGGAGCTTGGAGAGGTGATTTGCAAGTGCATGGGGGAAGCA GATCCATCCATTCAGCTTCATGGAGCAAAGCTTCTGGAAGAACTGGGCACAGGCTTAATACAGCAGTATAAACCAGACTCCACTGCAGCA CCTGATCAGAGAGCACCAGTCTTCTTGGTGGTGATGTTCTGGACTATGATGCTGAACGGTCCTTTACCCAGAGCCCTGCAGAATTCAGAA CACCCAACTCTCCAGGCGAGCGCCTGTGATGCCCTGTCTTCCATCTTGCCAGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGATGCTG TGCATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGCTTTTT CCCTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTCGAGCC AAAGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCTCTGGT CTCCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTGGAAAT TTGCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTACTGTT CTAACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGACAGCC CCATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTGCCCTT TCCGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGAGTGAA GACACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGGCCAGT GCCTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAGGAGCA GAGGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCCAGGCA CCAACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAGGGGCA CTCCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATAAGATC TGTGGGATTTCATCTTAGGGGCAGAAACAATCCGTTCACTATTTATTTAGAATGACTTAGCAGCCATTTAAATTTTCACAGAGGGCTCAA CCACCTTTGGAGTGACTCCATAGCACTGGCCATGGTCAGGGTTGTTGGAACATCTGACCTGTGCATCCAGGAGCCGAGGAGTCAGGTTGT AATACAGGCCAAGCAGACGGGCTTTGAGGGCATTTAGTCTCAGAAAAAAAAAATGTAGAAGGATTTCGGAATTAGAATTTTGTGTATTGT >82033_82033_7_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000578105_HEATR6_chr17_58137457_ENST00000184956_length(amino acids)=720AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLH GAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLG LNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKML RSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAY NALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCM KETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ -------------------------------------------------------------- >82033_82033_8_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000578105_HEATR6_chr17_58137457_ENST00000585976_length(transcript)=1919nt_BP=54nt GCGGAATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATC TTGGAAGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGC AGCATTAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCA AATTTAGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAA GATGTTAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAA CAGCCATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCC TCTCTGGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCC AAGGAGGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTCAGCAAT CTGCCGAATGACAGGCAGATGCTGTGCATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGG GCCCTGGGAGTCTATGTGCTTTTTCCCTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAA GACAAGTCTCTGAATGTTCGAGCCAAAGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCA AGTTTCCAGGAAGAGTTCTCTGGTCTCCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGC AATGCAGTCCGGGCCCTTGGAAATTTGCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCT ATCCAGGCCCTAATTTCTACTGTTCTAACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAAT CCTGCCCTTCCTTTAGGGACAGCCCCATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTG CGCATCAGATCTGCAGCTGCCCTTTCCGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTG GTCACCGCTTTACAGAAGAGTGAAGACACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTG ATTCACCTCTTGAGCTTGGCCAGTGCCTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATT CTACAGTTTTTAAAATCAGGAGCAGAGGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTT AAACACATGGGCAGCATCCAGGCACCAACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTT GACTCATCTGGATCACAAGGGGCACTCCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGA >82033_82033_8_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000578105_HEATR6_chr17_58137457_ENST00000585976_length(amino acids)=608AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVL FPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALG NLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAA LSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSG -------------------------------------------------------------- >82033_82033_9_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000581068_HEATR6_chr17_58137457_ENST00000184956_length(transcript)=2617nt_BP=118nt GACAGCTGTCCAATGGAGGCCCTCCGTGCTAGTACGGCTTGCGGCTTAAGCGCCGCCGCGGTCTGCGGAATGTCAACTATTCAACATGGA GGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGAAGGCTCAAAGCAGTTTCTTTC TGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCATTAGAGAGTTGCACAGATGTCT TTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTTAGTATCAAATGCACCTTATGA TCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGTTAATGTTCGTGTGTCAAGTCT CACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCCATGTTCTTCTGGACTCGGTAA TAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCTGGAAGAAACGTCAGTTAGCTC ACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGAGGATTCCTGTTCAGGTAGCGA TGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTACAGGTATTGACTCTTCTGGCAAGGGGCTACTT TTCAATGACTCAAGCCTACTTGATGGAGCTTGGAGAGGTGATTTGCAAGTGCATGGGGGAAGCAGATCCATCCATTCAGCTTCATGGAGC AAAGCTTCTGGAAGAACTGGGCACAGGCTTAATACAGCAGTATAAACCAGACTCCACTGCAGCACCTGATCAGAGAGCACCAGTCTTCTT GGTGGTGATGTTCTGGACTATGATGCTGAACGGTCCTTTACCCAGAGCCCTGCAGAATTCAGAACACCCAACTCTCCAGGCGAGCGCCTG TGATGCCCTGTCTTCCATCTTGCCAGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGATGCTGTGCATCACAGTGCTGCTCGGGCTGAA TGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGCTTTTTCCCTGTCTCAGACAGGATGTCATATT TGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTCGAGCCAAAGCAGCCTGGTCCCTGGGCAACCT GACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCTCTGGTCTCCTGCTCTTGAAAATGTTACGATC AGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTGGAAATTTGCTTCATTTTCTGCAACCCTCTCA TATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTACTGTTCTAACAGAAGCTGCCATGAAAGTCCG ATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGACAGCCCCATGGACCTCCCAGGCCTACAATGC CCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTGCCCTTTCCGTCCCGGGGAAGAGAGAGCAGTA CGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGAGTGAAGACACCATAGACTTTTTGGAATTCAA GTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGGCCAGTGCCTCGGACCTCCCTTGTATGAAAGA AACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAGGAGCAGAGGGAGATGACACTGGAGCACCCCA CAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCCAGGCACCAACTGGAGACACAGCCAGAAGGGC CATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAGGGGCACTCCCAGGGTTAACAAATCAGTGAAG ATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATAAGATCTGTGGGATTTCATCTTAGGGGCAGAA ACAATCCGTTCACTATTTATTTAGAATGACTTAGCAGCCATTTAAATTTTCACAGAGGGCTCAACCACCTTTGGAGTGACTCCATAGCAC TGGCCATGGTCAGGGTTGTTGGAACATCTGACCTGTGCATCCAGGAGCCGAGGAGTCAGGTTGTAATACAGGCCAAGCAGACGGGCTTTG AGGGCATTTAGTCTCAGAAAAAAAAAATGTAGAAGGATTTCGGAATTAGAATTTTGTGTATTGTATCTGTAGTTTTGTAATAAACTAACG >82033_82033_9_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000581068_HEATR6_chr17_58137457_ENST00000184956_length(amino acids)=720AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLH GAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLG LNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKML RSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAY NALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCM KETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ -------------------------------------------------------------- >82033_82033_10_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000581068_HEATR6_chr17_58137457_ENST00000585976_length(transcript)=1983nt_BP=118nt GACAGCTGTCCAATGGAGGCCCTCCGTGCTAGTACGGCTTGCGGCTTAAGCGCCGCCGCGGTCTGCGGAATGTCAACTATTCAACATGGA GGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGAAGGCTCAAAGCAGTTTCTTTC TGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCATTAGAGAGTTGCACAGATGTCT TTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTTAGTATCAAATGCACCTTATGA TCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGTTAATGTTCGTGTGTCAAGTCT CACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCCATGTTCTTCTGGACTCGGTAA TAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCTGGAAGAAACGTCAGTTAGCTC ACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGAGGATTCCTGTTCAGGTAGCGA TGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGATGCTGTG CATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGCTTTTTCC CTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTCGAGCCAA AGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCTCTGGTCT CCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTGGAAATTT GCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTACTGTTCT AACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGACAGCCCC ATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTGCCCTTTC CGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGAGTGAAGA CACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGGCCAGTGC CTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAGGAGCAGA GGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCCAGGCACC AACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAGGGGCACT CCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATAAGATCTG >82033_82033_10_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000581068_HEATR6_chr17_58137457_ENST00000585976_length(amino acids)=608AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVL FPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALG NLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAA LSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSG -------------------------------------------------------------- >82033_82033_11_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000583380_HEATR6_chr17_58137457_ENST00000184956_length(transcript)=2543nt_BP=44nt AACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGAAGGCT CAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCATTAGAG AGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTTAGTAT CAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGTTAATG TTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCCATGTT CTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCTGGAAG AAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGAGGATT CCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTACAGGTATTGACTCTTC TGGCAAGGGGCTACTTTTCAATGACTCAAGCCTACTTGATGGAGCTTGGAGAGGTGATTTGCAAGTGCATGGGGGAAGCAGATCCATCCA TTCAGCTTCATGGAGCAAAGCTTCTGGAAGAACTGGGCACAGGCTTAATACAGCAGTATAAACCAGACTCCACTGCAGCACCTGATCAGA GAGCACCAGTCTTCTTGGTGGTGATGTTCTGGACTATGATGCTGAACGGTCCTTTACCCAGAGCCCTGCAGAATTCAGAACACCCAACTC TCCAGGCGAGCGCCTGTGATGCCCTGTCTTCCATCTTGCCAGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGATGCTGTGCATCACAG TGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGCTTTTTCCCTGTCTCA GACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTCGAGCCAAAGCAGCCT GGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCTCTGGTCTCCTGCTCT TGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTGGAAATTTGCTTCATT TTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTACTGTTCTAACAGAAG CTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGACAGCCCCATGGACCT CCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTGCCCTTTCCGTCCCGG GGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGAGTGAAGACACCATAG ACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGGCCAGTGCCTCGGACC TCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAGGAGCAGAGGGAGATG ACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCCAGGCACCAACTGGAG ACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAGGGGCACTCCCAGGGT TAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATAAGATCTGTGGGATTT CATCTTAGGGGCAGAAACAATCCGTTCACTATTTATTTAGAATGACTTAGCAGCCATTTAAATTTTCACAGAGGGCTCAACCACCTTTGG AGTGACTCCATAGCACTGGCCATGGTCAGGGTTGTTGGAACATCTGACCTGTGCATCCAGGAGCCGAGGAGTCAGGTTGTAATACAGGCC AAGCAGACGGGCTTTGAGGGCATTTAGTCTCAGAAAAAAAAAATGTAGAAGGATTTCGGAATTAGAATTTTGTGTATTGTATCTGTAGTT >82033_82033_11_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000583380_HEATR6_chr17_58137457_ENST00000184956_length(amino acids)=720AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLH GAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLG LNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKML RSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAY NALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCM KETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ -------------------------------------------------------------- >82033_82033_12_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000583380_HEATR6_chr17_58137457_ENST00000585976_length(transcript)=1909nt_BP=44nt AACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGAAGGCT CAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCATTAGAG AGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTTAGTAT CAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGTTAATG TTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCCATGTT CTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCTGGAAG AAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGAGGATT CCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTCAGCAATCTGCCGAATG ACAGGCAGATGCTGTGCATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAG TCTATGTGCTTTTTCCCTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTC TGAATGTTCGAGCCAAAGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGG AAGAGTTCTCTGGTCTCCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCC GGGCCCTTGGAAATTTGCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCC TAATTTCTACTGTTCTAACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTC CTTTAGGGACAGCCCCATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGAT CTGCAGCTGCCCTTTCCGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTT TACAGAAGAGTGAAGACACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCT TGAGCTTGGCCAGTGCCTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTT TAAAATCAGGAGCAGAGGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGG GCAGCATCCAGGCACCAACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTG GATCACAAGGGGCACTCCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGC >82033_82033_12_SKA2-HEATR6_SKA2_chr17_57232491_ENST00000583380_HEATR6_chr17_58137457_ENST00000585976_length(amino acids)=608AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVL FPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALG NLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAA LSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSG -------------------------------------------------------------- >82033_82033_13_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000330137_HEATR6_chr17_58137457_ENST00000184956_length(transcript)=2638nt_BP=139nt AATGAGTGCGAGATGTTGAGTGACAGCTGTCCAATGGAGGCCCTCCGTGCTAGTACGGCTTGCGGCTTAAGCGCCGCCGCGGTCTGCGGA ATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGA AGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCAT TAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTT AGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGT TAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCC ATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCT GGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGA GGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTACAGGTATTGAC TCTTCTGGCAAGGGGCTACTTTTCAATGACTCAAGCCTACTTGATGGAGCTTGGAGAGGTGATTTGCAAGTGCATGGGGGAAGCAGATCC ATCCATTCAGCTTCATGGAGCAAAGCTTCTGGAAGAACTGGGCACAGGCTTAATACAGCAGTATAAACCAGACTCCACTGCAGCACCTGA TCAGAGAGCACCAGTCTTCTTGGTGGTGATGTTCTGGACTATGATGCTGAACGGTCCTTTACCCAGAGCCCTGCAGAATTCAGAACACCC AACTCTCCAGGCGAGCGCCTGTGATGCCCTGTCTTCCATCTTGCCAGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGATGCTGTGCAT CACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGCTTTTTCCCTG TCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTCGAGCCAAAGC AGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCTCTGGTCTCCT GCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTGGAAATTTGCT TCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTACTGTTCTAAC AGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGACAGCCCCATG GACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTGCCCTTTCCGT CCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGAGTGAAGACAC CATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGGCCAGTGCCTC GGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAGGAGCAGAGGG AGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCCAGGCACCAAC TGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAGGGGCACTCCC AGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATAAGATCTGTGG GATTTCATCTTAGGGGCAGAAACAATCCGTTCACTATTTATTTAGAATGACTTAGCAGCCATTTAAATTTTCACAGAGGGCTCAACCACC TTTGGAGTGACTCCATAGCACTGGCCATGGTCAGGGTTGTTGGAACATCTGACCTGTGCATCCAGGAGCCGAGGAGTCAGGTTGTAATAC AGGCCAAGCAGACGGGCTTTGAGGGCATTTAGTCTCAGAAAAAAAAAATGTAGAAGGATTTCGGAATTAGAATTTTGTGTATTGTATCTG >82033_82033_13_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000330137_HEATR6_chr17_58137457_ENST00000184956_length(amino acids)=720AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLH GAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLG LNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKML RSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAY NALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCM KETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ -------------------------------------------------------------- >82033_82033_14_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000330137_HEATR6_chr17_58137457_ENST00000585976_length(transcript)=2004nt_BP=139nt AATGAGTGCGAGATGTTGAGTGACAGCTGTCCAATGGAGGCCCTCCGTGCTAGTACGGCTTGCGGCTTAAGCGCCGCCGCGGTCTGCGGA ATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGA AGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCAT TAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTT AGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGT TAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCC ATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCT GGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGA GGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTCAGCAATCTGCC GAATGACAGGCAGATGCTGTGCATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCT GGGAGTCTATGTGCTTTTTCCCTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAA GTCTCTGAATGTTCGAGCCAAAGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTT CCAGGAAGAGTTCTCTGGTCTCCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGC AGTCCGGGCCCTTGGAAATTTGCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCA GGCCCTAATTTCTACTGTTCTAACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGC CCTTCCTTTAGGGACAGCCCCATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCAT CAGATCTGCAGCTGCCCTTTCCGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCAC CGCTTTACAGAAGAGTGAAGACACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCA CCTCTTGAGCTTGGCCAGTGCCTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACA GTTTTTAAAATCAGGAGCAGAGGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACA CATGGGCAGCATCCAGGCACCAACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTC ATCTGGATCACAAGGGGCACTCCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACC >82033_82033_14_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000330137_HEATR6_chr17_58137457_ENST00000585976_length(amino acids)=608AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVL FPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALG NLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAA LSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSG -------------------------------------------------------------- >82033_82033_15_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000578105_HEATR6_chr17_58137457_ENST00000184956_length(transcript)=2553nt_BP=54nt GCGGAATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATC TTGGAAGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGC AGCATTAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCA AATTTAGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAA GATGTTAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAA CAGCCATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCC TCTCTGGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCC AAGGAGGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTACAGGTA TTGACTCTTCTGGCAAGGGGCTACTTTTCAATGACTCAAGCCTACTTGATGGAGCTTGGAGAGGTGATTTGCAAGTGCATGGGGGAAGCA GATCCATCCATTCAGCTTCATGGAGCAAAGCTTCTGGAAGAACTGGGCACAGGCTTAATACAGCAGTATAAACCAGACTCCACTGCAGCA CCTGATCAGAGAGCACCAGTCTTCTTGGTGGTGATGTTCTGGACTATGATGCTGAACGGTCCTTTACCCAGAGCCCTGCAGAATTCAGAA CACCCAACTCTCCAGGCGAGCGCCTGTGATGCCCTGTCTTCCATCTTGCCAGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGATGCTG TGCATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGCTTTTT CCCTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTCGAGCC AAAGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCTCTGGT CTCCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTGGAAAT TTGCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTACTGTT CTAACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGACAGCC CCATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTGCCCTT TCCGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGAGTGAA GACACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGGCCAGT GCCTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAGGAGCA GAGGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCCAGGCA CCAACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAGGGGCA CTCCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATAAGATC TGTGGGATTTCATCTTAGGGGCAGAAACAATCCGTTCACTATTTATTTAGAATGACTTAGCAGCCATTTAAATTTTCACAGAGGGCTCAA CCACCTTTGGAGTGACTCCATAGCACTGGCCATGGTCAGGGTTGTTGGAACATCTGACCTGTGCATCCAGGAGCCGAGGAGTCAGGTTGT AATACAGGCCAAGCAGACGGGCTTTGAGGGCATTTAGTCTCAGAAAAAAAAAATGTAGAAGGATTTCGGAATTAGAATTTTGTGTATTGT >82033_82033_15_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000578105_HEATR6_chr17_58137457_ENST00000184956_length(amino acids)=720AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLH GAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLG LNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKML RSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAY NALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCM KETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ -------------------------------------------------------------- >82033_82033_16_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000578105_HEATR6_chr17_58137457_ENST00000585976_length(transcript)=1919nt_BP=54nt GCGGAATGTCAACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATC TTGGAAGGCTCAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGC AGCATTAGAGAGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCA AATTTAGTATCAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAA GATGTTAATGTTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAA CAGCCATGTTCTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCC TCTCTGGAAGAAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCC AAGGAGGATTCCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTCAGCAAT CTGCCGAATGACAGGCAGATGCTGTGCATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGG GCCCTGGGAGTCTATGTGCTTTTTCCCTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAA GACAAGTCTCTGAATGTTCGAGCCAAAGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCA AGTTTCCAGGAAGAGTTCTCTGGTCTCCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGC AATGCAGTCCGGGCCCTTGGAAATTTGCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCT ATCCAGGCCCTAATTTCTACTGTTCTAACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAAT CCTGCCCTTCCTTTAGGGACAGCCCCATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTG CGCATCAGATCTGCAGCTGCCCTTTCCGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTG GTCACCGCTTTACAGAAGAGTGAAGACACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTG ATTCACCTCTTGAGCTTGGCCAGTGCCTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATT CTACAGTTTTTAAAATCAGGAGCAGAGGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTT AAACACATGGGCAGCATCCAGGCACCAACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTT GACTCATCTGGATCACAAGGGGCACTCCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGA >82033_82033_16_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000578105_HEATR6_chr17_58137457_ENST00000585976_length(amino acids)=608AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVL FPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALG NLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAA LSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSG -------------------------------------------------------------- >82033_82033_17_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000581068_HEATR6_chr17_58137457_ENST00000184956_length(transcript)=2617nt_BP=118nt GACAGCTGTCCAATGGAGGCCCTCCGTGCTAGTACGGCTTGCGGCTTAAGCGCCGCCGCGGTCTGCGGAATGTCAACTATTCAACATGGA GGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGAAGGCTCAAAGCAGTTTCTTTC TGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCATTAGAGAGTTGCACAGATGTCT TTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTTAGTATCAAATGCACCTTATGA TCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGTTAATGTTCGTGTGTCAAGTCT CACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCCATGTTCTTCTGGACTCGGTAA TAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCTGGAAGAAACGTCAGTTAGCTC ACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGAGGATTCCTGTTCAGGTAGCGA TGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTACAGGTATTGACTCTTCTGGCAAGGGGCTACTT TTCAATGACTCAAGCCTACTTGATGGAGCTTGGAGAGGTGATTTGCAAGTGCATGGGGGAAGCAGATCCATCCATTCAGCTTCATGGAGC AAAGCTTCTGGAAGAACTGGGCACAGGCTTAATACAGCAGTATAAACCAGACTCCACTGCAGCACCTGATCAGAGAGCACCAGTCTTCTT GGTGGTGATGTTCTGGACTATGATGCTGAACGGTCCTTTACCCAGAGCCCTGCAGAATTCAGAACACCCAACTCTCCAGGCGAGCGCCTG TGATGCCCTGTCTTCCATCTTGCCAGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGATGCTGTGCATCACAGTGCTGCTCGGGCTGAA TGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGCTTTTTCCCTGTCTCAGACAGGATGTCATATT TGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTCGAGCCAAAGCAGCCTGGTCCCTGGGCAACCT GACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCTCTGGTCTCCTGCTCTTGAAAATGTTACGATC AGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTGGAAATTTGCTTCATTTTCTGCAACCCTCTCA TATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTACTGTTCTAACAGAAGCTGCCATGAAAGTCCG ATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGACAGCCCCATGGACCTCCCAGGCCTACAATGC CCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTGCCCTTTCCGTCCCGGGGAAGAGAGAGCAGTA CGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGAGTGAAGACACCATAGACTTTTTGGAATTCAA GTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGGCCAGTGCCTCGGACCTCCCTTGTATGAAAGA AACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAGGAGCAGAGGGAGATGACACTGGAGCACCCCA CAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCCAGGCACCAACTGGAGACACAGCCAGAAGGGC CATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAGGGGCACTCCCAGGGTTAACAAATCAGTGAAG ATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATAAGATCTGTGGGATTTCATCTTAGGGGCAGAA ACAATCCGTTCACTATTTATTTAGAATGACTTAGCAGCCATTTAAATTTTCACAGAGGGCTCAACCACCTTTGGAGTGACTCCATAGCAC TGGCCATGGTCAGGGTTGTTGGAACATCTGACCTGTGCATCCAGGAGCCGAGGAGTCAGGTTGTAATACAGGCCAAGCAGACGGGCTTTG AGGGCATTTAGTCTCAGAAAAAAAAAATGTAGAAGGATTTCGGAATTAGAATTTTGTGTATTGTATCTGTAGTTTTGTAATAAACTAACG >82033_82033_17_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000581068_HEATR6_chr17_58137457_ENST00000184956_length(amino acids)=720AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLH GAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLG LNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKML RSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAY NALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCM KETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ -------------------------------------------------------------- >82033_82033_18_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000581068_HEATR6_chr17_58137457_ENST00000585976_length(transcript)=1983nt_BP=118nt GACAGCTGTCCAATGGAGGCCCTCCGTGCTAGTACGGCTTGCGGCTTAAGCGCCGCCGCGGTCTGCGGAATGTCAACTATTCAACATGGA GGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGAAGGCTCAAAGCAGTTTCTTTC TGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCATTAGAGAGTTGCACAGATGTCT TTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTTAGTATCAAATGCACCTTATGA TCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGTTAATGTTCGTGTGTCAAGTCT CACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCCATGTTCTTCTGGACTCGGTAA TAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCTGGAAGAAACGTCAGTTAGCTC ACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGAGGATTCCTGTTCAGGTAGCGA TGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGATGCTGTG CATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGCTTTTTCC CTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTCGAGCCAA AGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCTCTGGTCT CCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTGGAAATTT GCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTACTGTTCT AACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGACAGCCCC ATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTGCCCTTTC CGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGAGTGAAGA CACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGGCCAGTGC CTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAGGAGCAGA GGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCCAGGCACC AACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAGGGGCACT CCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATAAGATCTG >82033_82033_18_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000581068_HEATR6_chr17_58137457_ENST00000585976_length(amino acids)=608AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVL FPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALG NLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAA LSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSG -------------------------------------------------------------- >82033_82033_19_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000583380_HEATR6_chr17_58137457_ENST00000184956_length(transcript)=2543nt_BP=44nt AACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGAAGGCT CAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCATTAGAG AGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTTAGTAT CAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGTTAATG TTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCCATGTT CTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCTGGAAG AAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGAGGATT CCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTACAGGTATTGACTCTTC TGGCAAGGGGCTACTTTTCAATGACTCAAGCCTACTTGATGGAGCTTGGAGAGGTGATTTGCAAGTGCATGGGGGAAGCAGATCCATCCA TTCAGCTTCATGGAGCAAAGCTTCTGGAAGAACTGGGCACAGGCTTAATACAGCAGTATAAACCAGACTCCACTGCAGCACCTGATCAGA GAGCACCAGTCTTCTTGGTGGTGATGTTCTGGACTATGATGCTGAACGGTCCTTTACCCAGAGCCCTGCAGAATTCAGAACACCCAACTC TCCAGGCGAGCGCCTGTGATGCCCTGTCTTCCATCTTGCCAGAGGCCTTCAGCAATCTGCCGAATGACAGGCAGATGCTGTGCATCACAG TGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAGTCTATGTGCTTTTTCCCTGTCTCA GACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTCTGAATGTTCGAGCCAAAGCAGCCT GGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGGAAGAGTTCTCTGGTCTCCTGCTCT TGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCCGGGCCCTTGGAAATTTGCTTCATT TTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCCTAATTTCTACTGTTCTAACAGAAG CTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTCCTTTAGGGACAGCCCCATGGACCT CCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGATCTGCAGCTGCCCTTTCCGTCCCGG GGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTTTACAGAAGAGTGAAGACACCATAG ACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCTTGAGCTTGGCCAGTGCCTCGGACC TCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTTTAAAATCAGGAGCAGAGGGAGATG ACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGGGCAGCATCCAGGCACCAACTGGAG ACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTGGATCACAAGGGGCACTCCCAGGGT TAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGCTTGAGCATAAGATCTGTGGGATTT CATCTTAGGGGCAGAAACAATCCGTTCACTATTTATTTAGAATGACTTAGCAGCCATTTAAATTTTCACAGAGGGCTCAACCACCTTTGG AGTGACTCCATAGCACTGGCCATGGTCAGGGTTGTTGGAACATCTGACCTGTGCATCCAGGAGCCGAGGAGTCAGGTTGTAATACAGGCC AAGCAGACGGGCTTTGAGGGCATTTAGTCTCAGAAAAAAAAAATGTAGAAGGATTTCGGAATTAGAATTTTGTGTATTGTATCTGTAGTT >82033_82033_19_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000583380_HEATR6_chr17_58137457_ENST00000184956_length(amino acids)=720AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLH GAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLG LNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKML RSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAY NALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCM KETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ -------------------------------------------------------------- >82033_82033_20_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000583380_HEATR6_chr17_58137457_ENST00000585976_length(transcript)=1909nt_BP=44nt AACTATTCAACATGGAGGCGGAGGTCGATAAGCTGGAACTGATGACACGTGCCTGTGCTCTGCAAGTTTTATCTGCCATCTTGGAAGGCT CAAAGCAGTTTCTTTCTGTTGCTGAAGATACCAGTGACCACAGAAGGGCTTTTACCCCCTTCTCCGTAATGATCGCTTGCAGCATTAGAG AGTTGCACAGATGTCTTTTGTTAGCTTTGGTGGCGGAGTCATCCTCACAGACCGTTACTCAGATAATTAAGTGCCTTGCAAATTTAGTAT CAAATGCACCTTATGATCGTCTAAAACTCAGCCTGCTGACCAAAGTCTGGAACCAGATAAAGCCTTATATTCGCCACAAAGATGTTAATG TTCGTGTGTCAAGTCTCACACTCTTGGGAGCTATAGTGTCCACCCACGCACCTTTACCTGAAGTCCAACTACTTCTGCAACAGCCATGTT CTTCTGGACTCGGTAATAGCAATTCAGCAACCCCTCACCTCAGCCCTCCTGATTGGTGGAAGAAAGCCCCTGCAGGACCCTCTCTGGAAG AAACGTCAGTTAGCTCACCTAAGGGGTCTTCAGAGCCCTGCTGGCTCATTCGACTCTGCATTTCCATTGTCGTACTGCCCAAGGAGGATT CCTGTTCAGGTAGCGATGCTGGCTCTGCAGCAGGAAGCACCTACGAACCATCCCCCATGCGACTGGAGGCCTTCAGCAATCTGCCGAATG ACAGGCAGATGCTGTGCATCACAGTGCTGCTCGGGCTGAATGACAGCAAGAATCGCTTAGTGAAAGCTGCAACTTCACGGGCCCTGGGAG TCTATGTGCTTTTTCCCTGTCTCAGACAGGATGTCATATTTGTTGCAGACGCAGCAAATGCAATATTGATGTCACTTGAAGACAAGTCTC TGAATGTTCGAGCCAAAGCAGCCTGGTCCCTGGGCAACCTGACAGACACTCTGATTGTCAACATGGAAACACCAGACCCAAGTTTCCAGG AAGAGTTCTCTGGTCTCCTGCTCTTGAAAATGTTACGATCAGCTATAGAAGCATCCAAGGATAAAGACAAGGTAAAAAGCAATGCAGTCC GGGCCCTTGGAAATTTGCTTCATTTTCTGCAACCCTCTCATATAGAAAAACCCACATTTGCAGAAATCATTGAGGAGTCTATCCAGGCCC TAATTTCTACTGTTCTAACAGAAGCTGCCATGAAAGTCCGATGGAATGCTTGTTATGCAATGGGAAATGTATTTAAAAATCCTGCCCTTC CTTTAGGGACAGCCCCATGGACCTCCCAGGCCTACAATGCCCTGACATCGGTCGTGACATCATGCAAGAACTTCAAAGTGCGCATCAGAT CTGCAGCTGCCCTTTCCGTCCCGGGGAAGAGAGAGCAGTACGGGTCTGTTGACCAGTATGCTCGGATCTGGAATGCATTGGTCACCGCTT TACAGAAGAGTGAAGACACCATAGACTTTTTGGAATTCAAGTACTGTGTCAGCCTACGGACCCAAATCTGCCAGGCACTGATTCACCTCT TGAGCTTGGCCAGTGCCTCGGACCTCCCTTGTATGAAAGAAACCCTTGAACTGAGTGGGAATATGGTCCAGTCCTATATTCTACAGTTTT TAAAATCAGGAGCAGAGGGAGATGACACTGGAGCACCCCACAGCCCACAGGAAAGAGACCAGATGGTCAGAATGGCCCTTAAACACATGG GCAGCATCCAGGCACCAACTGGAGACACAGCCAGAAGGGCCATCATGGGCTTTTTAGAAGAGATCCTGGCCGTTTGTTTTGACTCATCTG GATCACAAGGGGCACTCCCAGGGTTAACAAATCAGTGAAGATCCCACCATACTTTCTAGATGTCGAAGGCGGCAGTAGGAAGACCTGAGC >82033_82033_20_SKA2-HEATR6_SKA2_chr17_57232492_ENST00000583380_HEATR6_chr17_58137457_ENST00000585976_length(amino acids)=608AA_BP=11 MEAEVDKLELMTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAP YDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSV SSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVL FPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALG NLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAA LSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSG -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SKA2-HEATR6 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SKA2-HEATR6 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SKA2-HEATR6 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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