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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SKAP2-KIAA1244 (FusionGDB2 ID:82078) |
Fusion Gene Summary for SKAP2-KIAA1244 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SKAP2-KIAA1244 | Fusion gene ID: 82078 | Hgene | Tgene | Gene symbol | SKAP2 | KIAA1244 | Gene ID | 8935 | 57221 |
| Gene name | src kinase associated phosphoprotein 2 | ARFGEF family member 3 | |
| Synonyms | PRAP|RA70|SAPS|SCAP2|SKAP-HOM|SKAP55R | A7322|BIG3|C6orf92|KIAA1244|PPP1R33|dJ171N11.1 | |
| Cytomap | 7p15.2 | 6q23.3-q24.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | src kinase-associated phosphoprotein 2Fyn-associated phosphoprotein SKAP55 homologuePyk2/RAFTK-associated proteinSKAP-55HOMSKAP55 homologretinoic acid-induced protein 70src family-associated phosphoprotein 2src kinase-associated phosphoprotein of 5 | brefeldin A-inhibited guanine nucleotide-exchange protein 3protein phosphatase 1, regulatory subunit 33 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000539623, ENST00000345317, ENST00000489977, | ENST00000251691, | |
| Fusion gene scores | * DoF score | 8 X 6 X 4=192 | 4 X 4 X 2=32 |
| # samples | 8 | 6 | |
| ** MAII score | log2(8/192*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/32*10)=0.906890595608518 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SKAP2 [Title/Abstract] AND KIAA1244 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SKAP2(26883649)-KIAA1244(138491799), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | KIAA1244 | GO:0010923 | negative regulation of phosphatase activity | 19389623 |
| Fusion gene breakpoints across SKAP2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across KIAA1244 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-AR-A1AO-01A | SKAP2 | chr7 | 26883649 | - | KIAA1244 | chr6 | 138491799 | + |
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Fusion Gene ORF analysis for SKAP2-KIAA1244 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000539623 | ENST00000251691 | SKAP2 | chr7 | 26883649 | - | KIAA1244 | chr6 | 138491799 | + |
| In-frame | ENST00000345317 | ENST00000251691 | SKAP2 | chr7 | 26883649 | - | KIAA1244 | chr6 | 138491799 | + |
| intron-3CDS | ENST00000489977 | ENST00000251691 | SKAP2 | chr7 | 26883649 | - | KIAA1244 | chr6 | 138491799 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000345317 | SKAP2 | chr7 | 26883649 | - | ENST00000251691 | KIAA1244 | chr6 | 138491799 | + | 15247 | 621 | 314 | 7069 | 2251 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000345317 | ENST00000251691 | SKAP2 | chr7 | 26883649 | - | KIAA1244 | chr6 | 138491799 | + | 0.00062628 | 0.99937373 |
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Fusion Genomic Features for SKAP2-KIAA1244 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| SKAP2 | chr7 | 26883648 | - | KIAA1244 | chr6 | 138491798 | + | 8.34E-09 | 1 |
| SKAP2 | chr7 | 26883648 | - | KIAA1244 | chr6 | 138491798 | + | 8.34E-09 | 1 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SKAP2-KIAA1244 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:26883649/chr6:138491799) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SKAP2 | chr7:26883649 | chr6:138491799 | ENST00000345317 | - | 4 | 13 | 14_64 | 102 | 1096.6666666666667 | Region | Homodimerization |
| Tgene | KIAA1244 | chr7:26883649 | chr6:138491799 | ENST00000251691 | 0 | 34 | 583_796 | 28 | 2178.0 | Domain | Note=SEC7 | |
| Tgene | KIAA1244 | chr7:26883649 | chr6:138491799 | ENST00000251691 | 0 | 34 | 1492_1512 | 28 | 2178.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SKAP2 | chr7:26883649 | chr6:138491799 | ENST00000345317 | - | 4 | 13 | 116_219 | 102 | 1096.6666666666667 | Domain | PH |
| Hgene | SKAP2 | chr7:26883649 | chr6:138491799 | ENST00000345317 | - | 4 | 13 | 297_358 | 102 | 1096.6666666666667 | Domain | SH3 |
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Fusion Gene Sequence for SKAP2-KIAA1244 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >82078_82078_1_SKAP2-KIAA1244_SKAP2_chr7_26883649_ENST00000345317_KIAA1244_chr6_138491799_ENST00000251691_length(transcript)=15247nt_BP=621nt AGGCTCTTTCTTCTGGGGCCGGGAAAACCGAGGAATACACATGCGCAGTTGGACCCCTCAGGCCCTTCGTGTCCCTTCCCACCCATCTCC CCGCCCCGGCCCTCTGGGCGGGGCTGGGCCGACAGTCCAGCTGCAGCTCGCTGGAGATTCAGTGACTTCCTTGTTGTGAGCCCCGGCCCG GCAGTGTCCCGACTCGTAGCCCCGCTGTTCTTAATCCGGGCCGCTAGCCTGAGTCTAGGTCGCAGCCGCAGCCCCACCCCGTCGGTCACC TTTTCAGCGCAGGTCCTTTCCCCGCACGCCCTGCGCTCCCTAACATGCCCAACCCCAGCAGCACCTCCTCTCCCTACCCCCTCCCTGAGG AAATTAGGAACCTGTTGGCAGATGTTGAAACATTTGTAGCAGATATACTGAAAGGAGAAAATTTATCCAAGAAAGCAAAGGAAAAGAGAG AATCCCTTATTAAGAAGATAAAAGATGTAAAGTCTATCTATCTTCAGGAATTTCAAGACAAAGGTGATGCAGAAGATGGGGAAGAATATG ATGACCCTTTTGCTGGGCCTCCAGACACTATTTCATTAGCCTCAGAACGATATGATAAAGACGATGAAGCCCCCTCTGATGAAACTCTAG GTGGTCTGGATACCATTGTCAAGATCCCTCCACATGTACTGAGGGAGAAATGCCTGCTGCCTCTCCAGTTGGCTTTGGAATCCAAGAATG TGAAGCTGGCCCAACATGCTTTGGCAGGGATGCAGAAGCTTCTGTCGGAAGAGAGGTTTGTATCCATGGAAACAGATTCTGATGAGAAGC AGCTGCTCAATCAGATACTGAATGCCGTGAAAGTGACGCCTTCGCTCAACGAGGACCTGCAGGTGGAAGTGATGAAGGTTTTACTATGCA TCACCTACACGCCAACATTTGATCTGAATGGGAGTGCCGTGCTGAAGATCGCGGAGGTGTGCATTGAGACGTACATAAGCAGCTGTCACC AGCGTAGCATAAACACTGCTGTGCGGGCAACTCTCAGTCAAATGCTGAGTGACTTGACTTTACAGTTACGACAGAGGCAGGAGAATACGA TAATTGAAAACCCAGATGTCCCACAGGATTTCGGGAATCAAGGGTCAACAGTAGAGTCCCTCTGTGATGATGTTGTCTCTGTACTCACCG TCCTGTGTGAGAAGCTGCAAGCCGCCATAAATGACAGCCAGCAGCTGCAGCTTCTCTACCTGGAGTGCATCCTGTCTGTGCTCAGCAGCT CCTCCTCCTCCATGCACCTGCACAGGCGCTTCACGGACCTGATCTGGAAAAACCTCTGCCCTGCTCTCATCGTGATCTTGGGGAATCCAA TTCATGACAAAACCATCACCTCTGCTCACACCAGCAGCACCAGTACCAGCCTGGAGTCGGACTCTGCGTCTCCGGGAGTGTCTGACCACG GCCGAGGATCAGGCTGCTCCTGCACTGCGCCGGCCCTGAGCGGACCTGTGGCTCGGACTATCTATTACATCGCAGCCGAGCTGGTCCGGC TGGTGGGGTCTGTGGACTCCATGAAGCCCGTGCTCCAGTCCCTCTACCACCGAGTGCTGCTCTACCCCCCACCCCAGCACCGGGTGGAAG CCATCAAAATAATGAAAGAGATACTTGGGAGCCCACAGCGTCTCTGTGACTTGGCAGGACCCAGCTCCACTGAATCAGAGTCCAGAAAAA GATCAATTTCAAAAAGAAAGTCTCATCTGGATCTCCTCAAACTCATCATGGATGGCATGACCGAAGCATGCATCAAGGGTGGCATCGAAG CTTGCTATGCAGCCGTGTCCTGTGTCTGCACCTTGCTGGGTGCCCTGGATGAGCTCAGCCAGGGGAAGGGCTTGAGCGAAGGTCAGGTGC AACTGCTGCTTCTGCGCCTTGAGGAGCTGAAGGATGGGGCTGAGTGGAGCCGAGATTCCATGGAGATCAATGAGGCTGACTTCCGCTGGC AGCGGCGAGTGCTGTCCTCAGAACACACGCCGTGGGAGTCAGGGAACGAGAGGAGCCTTGACATCAGCATCAGTGTCACCACAGACACAG GCCAGACCACTCTCGAGGGAGAGTTGGGTCAGACTACACCCGAGGACCATTCGGGAAACCACAAGAACAGTCTCAAGTCGCCAGCCATCC CAGAGGGTAAGGAGACGCTGAGCAAAGTATTGGAAACAGAGGCGGTAGACCAGCCAGATGTCGTGCAGAGAAGCCACACGGTCCCTTACC CTGACATAACTAACTTCCTGTCAGTAGACTGCAGGACAAGGTCCTATGGATCTAGGTATAGTGAGAGCAATTTTAGCGTTGATGACCAAG ACCTTTCTAGGACAGAGTTTGATTCCTGTGATCAGTACTCTATGGCAGCAGAAAAGGACTCGGGCAGGTCCGACGTGTCAGACATTGGGT CGGACAACTGTTCACTAGCCGATGAAGAGCAGACACCCCGGGACTGCCTAGGCCACCGGTCCCTGCGAACTGCCGCCCTGTCTCTAAAAC TGCTGAAGAACCAGGAGGCGGATCAGCACAGCGCCAGGCTGTTCATACAGTCCCTGGAAGGCCTCCTCCCTCGGCTCCTGTCTCTCTCCA ATGTAGAGGAGGTGGACACCGCTCTGCAGAACTTTGCCTCTACTTTCTGCTCAGGCATGATGCACTCTCCTGGCTTTGACGGGAATAGCA GCCTCAGCTTCCAGATGCTGATGAACGCAGACAGCCTCTACACAGCTGCACACTGCGCCCTGCTCCTCAACCTGAAGCTCTCCCACGGTG ACTACTACAGGAAGCGGCCGACCCTGGCGCCAGGCGTGATGAAGGACTTCATGAAGCAGGTGCAGACCAGCGGCGTGCTGATGGTCTTCT CTCAGGCCTGGATTGAGGAGCTCTACCATCAGGTGCTCGACAGGAACATGCTTGGAGAGGCTGGCTATTGGGGCAGCCCAGAAGATAACA GCCTTCCCCTCATCACAATGCTGACCGATATTGACGGCTTAGAGAGCAGTGCCATTGGTGGCCAGCTGATGGCCTCGGCTGCTACAGAGT CTCCTTTCGCCCAGAGCAGGAGAATTGATGACTCCACAGTGGCAGGCGTGGCATTTGCTCGCTATATTCTGGTGGGCTGCTGGAAGAACT TGATCGATACTTTATCAACCCCACTGACTGGTCGAATGGCGGGGAGCTCCAAAGGGCTGGCCTTCATTCTGGGAGCTGAAGGCATCAAAG AGCAGAACCAGAAGGAGCGGGACGCCATCTGCATGAGCCTCGACGGGCTGCGGAAAGCCGCACGGCTGAGCTGCGCTCTAGGCGTTGCTG CTAACTGCGCCTCAGCCCTTGCCCAGATGGCAGCTGCCTCCTGTGTCCAAGAAGAAAAAGAAGAGAGGGAGGCCCAAGAACCCAGTGATG CCATCACACAAGTGAAACTAAAAGTGGAGCAGAAACTGGAGCAGATTGGGAAGGTGCAGGGGGTGTGGCTGCACACTGCCCACGTCTTGT GCATGGAGGCCATCCTCAGCGTAGGCCTGGAGATGGGAAGCCACAACCCGGACTGCTGGCCACACGTGTTCAGGGTGTGTGAATACGTGG GCACCCTGGAGCACAACCACTTCAGCGATGGTGCCTCGCAGCCCCCTCTGACCATCAGCCAGCCCCAGAAGGCCACTGGAAGCGCTGGCC TCCTTGGGGACCCCGAGTGTGAGGGCTCGCCCCCCGAGCACAGCCCGGAGCAGGGGCGCTCCCTGAGCACGGCCCCTGTCGTCCAGCCCC TGTCCATCCAGGACCTCGTCCGGGAAGGCAGCCGGGGTCGGGCCTCCGACTTCCGCGGCGGGAGCCTCATGAGCGGGAGCAGCGCGGCCA AGGTGGTGCTCACCCTCTCCACGCAAGCCGACAGGCTCTTTGAAGATGCTACGGATAAGTTGAACCTCATGGCCTTGGGAGGTTTTCTTT ACCAGCTGAAGAAAGCATCGCAGTCTCAGCTTTTCCATTCTGTTACAGATACAGTTGATTACTCTCTGGCAATGCCAGGAGAAGTTAAAT CCACTCAAGACCGAAAAAGCGCCCTCCACCTGTTCCGCCTGGGGAATGCCATGCTGAGGATTGTGCGGAGCAAAGCACGGCCCCTGCTCC ACGTGATGCGCTGCTGGAGCCTTGTGGCCCCACACCTGGTGGAGGCTGCTTGCCATAAGGAAAGACATGTGTCTCAGAAGGCTGTTTCCT TCATCCATGACATACTGACAGAAGTCCTCACTGACTGGAATGAGCCACCTCATTTTCACTTCAATGAAGCACTCTTCCGACCTTTCGAGC GCATTATGCAGCTGGAATTGTGTGATGAGGACGTCCAAGACCAGGTTGTCACATCCATTGGTGAGCTGGTTGAAGTGTGTTCCACGCAGA TCCAGTCGGGATGGAGACCCTTGTTCAGTGCCCTGGAAACAGTGCATGGCGGGAACAAGTCAGAGATGAAGGAGTACCTGGTTGGTGACT ACTCCATGGGAAAAGGCCAAGCTCCAGTGTTTGATGTATTTGAAGCTTTTCTCAATACTGACAACATCCAGGTCTTTGCTAATGCAGCCA CTAGCTACATCATGTGCCTTATGAAGTTTGTCAAAGGACTGGGGGAGGTGGACTGTAAAGAGATTGGAGACTGTGCCCCAGCACCCGGAG CCCCGTCCACAGACCTGTGCCTCCCGGCCCTGGATTACCTCAGGCGCTGCTCTCAGTTATTGGCCAAAATCTACAAAATGCCCTTGAAGC CAATATTCCTTAGTGGGAGACTTGCCGGCTTGCCTCGAAGACTTCAGGAACAGTCAGCCAGCAGTGAGGATGGAATTGAATCAGTCCTGT CTGATTTTGATGATGACACCGGTCTGATAGAAGTCTGGATAATCCTGCTGGAGCAGCTGACAGCGGCTGTGTCCAATTGTCCACGGCAGC ACCAACCACCAACTCTGGATTTACTCTTTGAGCTGTTGAGAGATGTGACGAAAACACCAGGACCAGGGTTTGGTATCTATGCAGTGGTTC ACCTCCTCCTTCCTGTGATGTCCGTTTGGCTCCGCCGGAGCCATAAAGACCATTCCTACTGGGATATGGCCTCTGCCAATTTCAAGCACG CTATTGGTCTGTCCTGTGAGCTGGTGGTGGAGCACATTCAAAGCTTTCTACATTCAGATATCAGGTACGAGAGCATGATCAATACCATGC TGAAGGACCTCTTTGAGTTGCTGGTCGCCTGTGTGGCCAAGCCCACTGAAACCATCTCCAGAGTGGGCTGCTCCTGTATTAGATACGTCC TTGTGACAGCGGGCCCTGTGTTCACTGAGGAGATGTGGAGGCTTGCCTGCTGTGCCCTGCAAGATGCGTTCTCTGCCACACTCAAGCCAG TGAAGGACCTGCTGGGCTGCTTCCACAGCGGCACGGAGAGCTTCAGCGGGGAAGGCTGCCAGGTGCGAGTGGCGGCCCCGTCCTCCTCCC CAAGTGCCGAGGCCGAGTACTGGCGCATCCGAGCCATGGCCCAGCAGGTGTTTATGCTGGACACCCAGTGCTCACCAAAGACACCAAACA ACTTTGACCACGCTCAGTCCTGCCAGCTCATTATTGAGCTGCCTCCTGATGAAAAACCAAATGGACACACCAAGAAAAGCGTGTCTTTCA GGGAAATTGTGGTGAGCCTGCTGTCTCATCAGGTGTTACTCCAGAACTTATATGACATCTTGTTAGAAGAGTTTGTCAAAGGCCCCTCTC CTGGAGAGGAAAAGACGATACAAGTGCCAGAAGCCAAGCTGGCTGGCTTCCTCAGATACATCTCTATGCAGAACTTGGCAGTCATATTCG ACCTGCTGCTGGACTCTTATAGGACTGCCAGGGAGTTTGACACCAGCCCCGGGCTGAAGTGCCTGCTGAAGAAAGTGTCTGGCATCGGGG GCGCCGCCAACCTCTACCGCCAGTCTGCGATGAGCTTTAACATTTATTTCCACGCCCTGGTGTGTGCTGTTCTCACCAATCAAGAAACCA TCACGGCCGAGCAAGTGAAGAAGGTCCTTTTTGAGGACGACGAGAGAAGCACGGATTCTTCCCAGCAGTGTTCATCTGAGGATGAAGACA TCTTTGAGGAAACCGCCCAGGTCAGCCCCCCGAGAGGCAAGGAGAAGAGACAGTGGCGGGCACGGATGCCCTTGCTCAGCGTCCAGCCTG TCAGCAACGCAGATTGGGTGTGGCTGGTCAAGAGGCTGCACAAGCTGTGCATGGAACTGTGCAACAACTACATCCAGATGCACTTGGACC TGGAGAACTGTATGGAGGAGCCTCCCATCTTCAAGGGCGACCCGTTCTTCATCCTGCCCTCCTTCCAGTCCGAGTCATCCACCCCATCCA CCGGGGGCTTCTCTGGGAAAGAAACCCCTTCCGAGGATGACAGAAGCCAGTCCCGGGAGCACATGGGCGAGTCCCTGAGCCTGAAGGCCG GTGGTGGGGACCTGCTGCTGCCCCCCAGCCCCAAAGTGGAGAAGAAGGATCCCAGCCGGAAGAAGGAGTGGTGGGAGAATGCGGGGAACA AAATCTACACCATGGCAGCCGACAAGACCATTTCAAAGTTGATGACCGAATACAAAAAGAGGAAACAGCAGCACAACCTGTCCGCGTTCC CCAAAGAGGTCAAAGTGGAGAAGAAAGGAGAGCCACTGGGTCCCAGGGGCCAGGACTCCCCGCTGCTTCAGCGTCCCCAGCACTTGATGG ACCAAGGGCAAATGCGGCATTCCTTCAGCGCAGGCCCCGAGCTGCTGCGACAGGACAAGAGGCCCCGCTCAGGCTCCACCGGGAGCTCCC TCAGTGTCTCGGTGAGAGACGCAGAAGCACAGATCCAGGCATGGACCAACATGGTGCTAACAGTTCTCAATCAGATTCAGATTCTCCCAG ACCAGACCTTCACGGCCCTCCAGCCCGCAGTGTTCCCGTGCATCAGTCAGCTGACCTGTCACGTGACCGACATCAGAGTTCGCCAGGCTG TGAGGGAGTGGCTGGGCAGGGTGGGCCGTGTCTATGACATCATTGTGTAGCCGACTCCTGTTCTACTCTCCCACCAAATAACAGTAGTGA GGGTTAGAGTCCTGCCAATACAGCTGTTGCATTTTCCCCACCACTAGCCCCACTTAAACTACTACTACTGTCTCAGAGAACAGTGTTTCC TAATGTAAAAAGCCTTTCCAACCACTGATCAGCATTGGGGCCATACTAAGGTTTGTATCTAGATGACACAAACGATATTCTGATTTTGCA CATTATTATAGAAGAATCTATAATCCTTGATATGTTTCTAACTCTTGAAGTATATTTCCCAGTGCTTTTGCTTACAGTGTTGTCCCCAAA TGGGTCATTTTCAAGGATTACTCATTTGAAAACACTATATTGATCCATTTGATCCATCATTTAAAAAATAAATACAATTCCTAAGGCAAT ATCTGCTGGTAAGTCAAGCTGATAAACACTCAGACATCTAGTACCAGGGATTATTAATTGGAGGAAGATTTATGGTTATGGGTCTGGCTG GGAAGAAGACAACTATAAATACATATTCTTGGGTGTCATAATCAAGAAAGAGGTGACTTCTGTTGTAAAATAATCCAGAACACTTCAAAA TTATTCCTAAATCATTAAGATTTTCAGGTATTCACCAATTTCCCCATGTAAGGTACTGTGTTGTACCTTTATTTCTGTATTTCTAAAAGA AGAAAGTTCTTTCCTAGCAGGGTTTGAAGTCTGTGGCTTATCAGCCTGTGACACAGAGTACCCAGTGAAAGTGGCTGGTACGTAGATTGT CAAGAGACATAAGACCGACCAGCCACCCTGGCTGTTCTTGTGGTGTTTGTTTCCATCCCCAAGGCAAACAAGGAAAGGAAAGGAAAGAAG AAAAGGTGCCTTAGTCCTTTGTTGCACTTCCATTTCCATGCCCCACAATTGTCTGAACATAAGGTATAGCATTTGGTTTTTAAGAAAACA AAACATTAAGACGCAACTCATTTTATATCAACACGCTTGGAGGAAAGGGACTCAGGGAAGGGAGCAGGGAGTGTGGGGTGGGGATGGATT ATGATGAAATCATTTTCAATCTTAAAATATAATACAACAATCTTGCAAAATTATGGTGTCAGTTACACAAGCTCTAGTCTCAAAATGAAA GTAATGGAGAAAGACACTGAAATTTAGAAAATTTTGTCGATTTAAAATATTTCTCCTATCTACCAAGTAAAGTTACCCTATGTTTGATGT CTTTGCATTCAGACCAATATTTCAGGTGGATATTTCTAAGTATTACTAGAAAATACGTTTGAAAGCTTTATCTTATTATTTACAGTATTT TTATATTTCTTACATTATCCTAATGATTGAAAACTCCTCAATCAAGCTTACTTACACACATTCTACAGAGTTATTTAAGGCATACATTAT AATCTCCCAGCCCCATTCATAATGAATAAGTCACCCTTTAAATATAAGACACAAATTCTACAGTATTGAAATAAGGATTTAAAGGGGTAT TTGTAAACTTTGCCCTCCTTGAGAAATATGGAACTACCTTAGAGGTTAAGAGGAAGGCAGTGTTCTGACTTCTTTAGGTGATCTGAAAAA AACACCCTTATCATCCAGTGTACCATCTAGAGATCACCACAGAATCCATTTTTTTCCCAGTTCCACAAAACACTCTGTTTGCCTTCAGTT TTTACTCACTAGACAATAATTCAAGTTTAGAAACAGGTAATCAGCTATTTGATCTTAAAAGGCAATGAATTGTTGGGATATCAGTGAACT ATGTTGTATACTTTTGAATTTTTACATTTTATAAATGGAATTGAAAGTTGGATAACTGCTTTTTTTAAATTTTCCAACAGAAGTAACACC ACAGTTGCTTTGTTTCTTTTTATAGCTTACCTGAGGTTCAGTTCTTCTTTGTGAACCTGTGAGTACTCCACAGTTTACTGGGGGAAAAGG CTTCAGTAAAGCAGAGGCTAGAATTACAGTATTTATACATAGCAACTTTTCATAAAGTAGAAAAATTCAAAGGAAGCTGTCTCAATTTGA GAATACCAGCTGGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTACTTTGGGAGGCCAAGGTGGGCAGATAACCTGCGGTCAGGAGTT TGAGACCAGGCTGGACAACATGGTGAAACCTCGTCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTAGGATGCACCTGTAATCCCAG CTACTTAGGAGGCCGAGACAGGAGAATCGCTCGAACCCAGGAGGCGGACGTTGCAGTGAGCCAAGATTGCACCATTGCACTCCAGACTGG GTGACAAGAGTGAAACTCCATCTAAAAAAAAAAAAAAAAAAAAGTGAATACTGTATCCCAAAGTATGTTAGTTGTTTGTTTGGAAATCAG CATTCTCCCCGATGCTCTATTATGGGATCCAAAATTCTTGAACATAAGTTTACCCTGTACTGTGTCCAAACACTGTTCTAGTTCTAGCCT GATTATGGGTCCCAAGAATAAAAGGATGAGTAGGTGTACAGAGCTCTTGACCTACAATTTTTTAAGAGTGTTTTGGTACCTTCCCATTGT CTTCTCTATAACTCAGTCCTAACATACTCTGCACTCGAGTTACCAGCCATCCACACTGACATCAGATTTCAACCAGAACCATCACTGAGT GACAGCAGTACTTCTCAGAGGTATTTGCAGCTTGATGCAAAGTAGTCTCTAATGAGTAGGCATTCAGGTGGTTCTTCCCAGCAGGTGGAG AAGAAAGGGAGGAGATGAAGAACACTGAGAGGGGAGTGGCACCTTCCCAGGCTGCCCAGCTCAGTCTCTTGCCCTGTTCCTGTGACTCAG CTGCCCACTCCCCCAACTTTGTTTCCCTCCCTCCCAGTCTCTGAAAGTGTCAGGTGTTTCTCTCCTCACAGTCTCTTTTGCAGCAACAGT AAGACAAAATTCAAGGCAGCCTTTTAAAGTTACGAACAGTTATTAGCATGTATTTACAGACCTAAGCAGAATGAGAGTTTATACATTGTT TTTAGTTGCCTGTATTTATAGCCAAAAGTATATTACCTTAAAGTTGAGATCTTTCTCTTCTTTTCCTAAATTTTGGTAAAGTGTGCTTCA TGAAACAAACATCTGGAAAACTCCAAGTATAAGAGACCCTGGACTGATGATGGCCCAGCCAAGTATATGGAGGGACAGAGTTCTCTCTGT CATTAATGAGGACATCGGTTTTCACAATTGAACCTCATGCACTGTCCACAGCATCTCACCTAGCTCCTGTATCTCCTGATCTGCTTTTAA AAATAGTTAGTTAGGCTGCCTTTTTACACCACCTTCTCTCTCTCCCCTTGTGGTAATTTTCCAGCCTTCCCCATAGATATAAAACTAGAA CACCTTTATGATTTGGGGTCTATGTAATGACTGACCGATAAGAACCCAGGCAGATGCTAACATACTTAACAGCTCGCATTAAAATACTTT AAATCAGGCGTGATGGCTCATTCCTGTAATCTCAAGCACTTTGGGAGGCTAAGGTGGGTGGATCTCTTGAGGTCAGGAGTTCGAGACCAA CCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAATACAAAATTAGCCGGGCATGGTGGCAGCTGCCTGTAATCCCAGCTACTCGGGA AGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGTGGGGATTGCAGTCAGCCAAGATTGTTCTGCAGCATGGGTGACAAAGTGAGACTTC GTCTCAAGTAAATAAAACTAAAATTTTTAAATCAAACATGACAAAAATGTTAATATAATTCAGAAGTACCTTGAAATTGAAACATATTTG TGCAATGATCATTAGGCTTTTTGTCCTTGTTGTTTTAAAATGAGGCTTATACAGAGTGAGTTGAGAGTCAAGTAGCCTTCGCTGTGAGAC GGTAATGCAGTTATATAATAGATACCCTTGACTTTGCCAGATTCATCACAATACTGCTTATACAGGAAAGTTTTCTCAGAAAGGAAAATC CATTAGTATCAGTCCCATCAAGCCAAACAGAATGAAGACCTTTGATAGTAATAGCAAGAGGTTACAAATAGCAGGGAGGAGGCGAGTAGT GAATGTCACTGTGATTGCAAACCCTTACCTGTATTATCACACGTAGTCCTCACAACAACCTTGTGAGACAAGTGTTGTGTTCCTCATTTT TTCAGAGGGGAACACAGACCCAGAGAGGTTAAGAAATTTGCCCAAGATAACAAGTAAAAGGCAAAGTTGGTTGCAAAAGAGGTGTTTCTG AATTCAAGGGCCATACTCTCTCTCTGACAACATGCTCTAAGTCCATAGAGTAAGCACTCTAGTATGAAAAAAAGTTTCAAGGAACGAGGC CATGAAAATGAGACTATTTGACATCTCAGATCTGTCTGGGATGTTATGGAGGTTTTTAAAAATAAAGTTGAAAAAAGAAAATGAATCATG TTTATACATAAAAAAATCACATGTAACACATTTCAAGTGTTTGAAAATAAAACCAAAATCTAAACTTTAGTCTTCAAGCAGACATTCAGT GTTACTTTAGAAAACTCACTGAATTAGGTGGAAATGATGGAATAATACTATTCATGGCCAGCTATTAACACAGAAGAACATGGCAGTGTG TGTCTGGAACGGCATGCACAATTTGTAAACCTTTTTCAAATATCATTTAATCAACTCAGAATAAAGTGCCCTGTAGCCAACAGTGCCTCT TTACTTGCTTCTCTGGGAAATACATGGTACTAAATTAGTAGCACAAAGTTTGGGAATATGCAAAATAATGGATAACCATTTTTCAAAATG TACATTCTCTGAAGAGGAAGCAGCTGGTTGGACAGGATTTCTTGAAGAGCCAGGTGCTAAGGGCATCAGGTCGACATCCATAGTAACCAT GTGCCATAACATCTACACATTTCCACTTGTTTTACAGACAAGGTAACAGGCAGAAGGAAAATCCAGAGTCTTGCAGTAAGCAGATGACAA AACTTCAATATGCTTGGGCACCACTTAGGTGACCCCAGGGAGATTTAGTGTGGCCTTAGGAAAGCAAAAGAGCACTTTTTATTGGAAATA TGAGCTTGTCACTGGGAAAGATTTGTAAAATTGATCAAGAACTTGATTTATAATTATGCCTCAAAAAAAAAAGTTCTCATTTAGTAGTGG AGCAATCTAGAAAACATACCTTTTTTGTTTGTTTGGAAGATCCTCTTTCCCTGGCTGTATTGTAGTGTTTGCTATTTGATGTGGAAATAA CTAATAACTTAAGATTTTGGAACAGAACACCCTTTAGATTTCCAAAACACAATTCTTATTTCAGGGAAGACAGACCAAAAATATCTCCTG AGATCATTGGTTTCTTTATAAATTGTGGTACCACTCCATCATTGAAGAGAAACCACTACCACACCACTAGCACCATACAGAACCTTTTCT CTGTATCTTTGTACAATACTACAAAGGGGTACCAGGGAGGAGAGAGTGGCTGACCACTTTAGTGACAAAACAGCACTCCACTGCTGGTGA ATCCCATCTAATTATGGTCCTTCCACCCTTTTCAACCACCAACAACTGTTCGTACTGTTAATTCCTATCCTGAAGGTTTAACCAGTGGTT GTCTAGTATCTTCTGTCTTTAGAACAGTGGTTCTCAAACTTTAGTACACATCAGCATCACCTGGAGGGCCTTTTTTTAAAATAAGACACA GATTGCTGGGCTCATGGTCAGAGTTCCCAGTTAAGTAAATCAGGAAATTTGTATTTCTAACAAGTTTATAGGTGAGGCCAATACTGCTGT TTTGGGAACTATGCTTTGAGAACCACTGCCTTGAAAAAATTTCCAACTTCTACCTTTAAGATCAGCCTGACTTATCAAACGCTAGAGAAA AACTGAATCTACCCTTGGGCAGATGACTTGGGATTGGATTCTATACAGCAGTCTTGCTCAATCTTCCCAGTTTCCAGTTTTATTATACCA ACAATTGGTTTTTACAAGCTAGAAGACAATGAATGTATAAGTTCTATGGAACAGTGAGATAAATCTAAGCTTCTTGTCTTTGTATTTAGA AACATTGATTCTATGGATGATCATTTGTATCATGTTGACCCTTTGACTTGTACTGAAGGTGATTTTAAATTTAAGTATGTAGTGTTTGAA TTTCTTCCATCCATGTCGTTTTAATGAGATGTTTCCATGTCAGCTCCTTTACAGCCTTGGCTCCTGGCTTACAGATTTTTGAATAGTTGT TTGCTTGCCAGTTGTTTTACATCTTTCATTGGCCACCAAAATATTAGCCATTTGAGATGAGATGAGACTACTTGTTGTACCTTCATCTTT CATTTAATTTTCTGGCGTAAATTAACATTTTAATTTCATATATATCTGTAAAGAGTCTACCCAAAGGCTTCACGGAAATTTGCAAAATGA ACTAATTCCCTTTTAAGCAGCAGGTGTGCCTGTTTTTGACTTTTCAGTAAATATGTTGTTTGTGCACATATCTACATGGTGGAGACCATA TTCATTATTTCATCTTCCAAATAATGGGAAAAATATAAAAGTGAATCAGTGTGCTTTGGGAATTCAGTGAAATCATGTTAACTCATATAG AGGGGGCCTTAGTTTATCTCTTCTTTACTGAATTAATTAGTTTTGGAAATTCTTTTACCATTAAAAAAAATTAAGGACCATACAGAGAAT GATTTAAGAAAAAACAAGTCACTTAAAAATCATCACCTATTTATAAACTGTATTAATTACACATAATGCTTATTGATTCAATGAGGTTTC TCTAAAGACTTCTGCTTAATAAATATGCTGACTTCATTTAAATTAGTTTAGACTATTGTAGGAATGGAAGGAAATGATTATATTTACTAG AATTAGTGAGATCAGAAAGCATATCAGAATGTTGATGATATCAAGGAGACAATCTACAGAGTTTTTGCCTCTGTGGATGGAAATAAGGGT GTTTTTTTTTGGTTTTTTTTTTACTTTAGTTTCCCATAATTTTTGGAAATTATGTGTGCATTTAGTTCTTTTAGTAACACTGATTTTAAA ATTAAATTTCAAAAGTCAATCTCTAAGAGTAATTTATTTTTGTTTTACCAACCAGTGCCAAAAAGGAGAGGAGGGAATCCAAAAGCCAAT CTTTTGAACCAATGTGTAAAAGATTATGTTTTTTCTTAAAGTTAGGGAGGCTCGGGCCCTGACACTGCCAGCCCCAGTGAGCATCCCTGG CTACCTCGGGATTATGTGCAAGCTGCTTTGTCCTACATTTCTTTCATCTGGTTCTTATTGGGAGTGCTTCTCTCTAATAAAAATTGATTT CCCACAAAATAGGCAAAGCTGAACAAAGATGAATGCTTTTGATAAGTTGGGTTTCACTTCAGTTGAAACAATGTGATAGAATATCCAGGT GTGGCATGATGGGGCAGGAGGAGGTGCCTAGAGGGAAAAGTTATTTTTGTTTCTTAGTGTTGTGTTGTGGGGATGGGACAGATAAGAATA AGATGTTTATTGCCCTAATCATGCTAAGAGACTATTATTCAATATGCTTTTCCCGCTTTTCTAAGAGGAATAAACTTAGACAAATTACAT TATAAACAGTTCCCCTACTACTATCTCCCACTCTAGATAAAGCCAGTGGGTGGTATGGGTCCTTTTATTCCTTATAGTATTATGCCAAAG AATCAACTTATTTTCATTGAAGATTATAAATAAATGAAGCTTGTTATAGCCATAATGATTTGAGTCAGTATACCATTTTACCTATAAAAT GCAAAATTCATCCTTGCAACCCCATTCACCAGGAGCCTTGAAGCATTTTGTTTACTCCAAAGGCCTTGTCAAGGAAGCATAATTTTTTGT TTTGCCTTCTTATTTAGTCAGTTTGGTCATATTTACTTAAAAAAACAAACTGAAAATCACACTCCTTTATATGTTGATATAACTGATTTT ATAGAATCTGTCTGTTCTTTGTTTAACAGGTCTCTGTAAGCAAGCTTGCAAGTGTATTTTGTGTACATTTTATCTGAGGTGGAAATGAAA ATTCTAAAGAGAAAATATTTTAAAAGATATTGTATTTATGTTGCTTGTGTTGTAGAATAAAGATTCAAATGCATTAAAAATCTGGTACAT >82078_82078_1_SKAP2-KIAA1244_SKAP2_chr7_26883649_ENST00000345317_KIAA1244_chr6_138491799_ENST00000251691_length(amino acids)=2251AA_BP=102 MPNPSSTSSPYPLPEEIRNLLADVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYLQEFQDKGDAEDGEEYDDPFAGPPDTISLAS ERYDKDDEAPSDETLGGLDTIVKIPPHVLREKCLLPLQLALESKNVKLAQHALAGMQKLLSEERFVSMETDSDEKQLLNQILNAVKVTPS LNEDLQVEVMKVLLCITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAVRATLSQMLSDLTLQLRQRQENTIIENPDVPQDFGNQG STVESLCDDVVSVLTVLCEKLQAAINDSQQLQLLYLECILSVLSSSSSSMHLHRRFTDLIWKNLCPALIVILGNPIHDKTITSAHTSSTS TSLESDSASPGVSDHGRGSGCSCTAPALSGPVARTIYYIAAELVRLVGSVDSMKPVLQSLYHRVLLYPPPQHRVEAIKIMKEILGSPQRL CDLAGPSSTESESRKRSISKRKSHLDLLKLIMDGMTEACIKGGIEACYAAVSCVCTLLGALDELSQGKGLSEGQVQLLLLRLEELKDGAE WSRDSMEINEADFRWQRRVLSSEHTPWESGNERSLDISISVTTDTGQTTLEGELGQTTPEDHSGNHKNSLKSPAIPEGKETLSKVLETEA VDQPDVVQRSHTVPYPDITNFLSVDCRTRSYGSRYSESNFSVDDQDLSRTEFDSCDQYSMAAEKDSGRSDVSDIGSDNCSLADEEQTPRD CLGHRSLRTAALSLKLLKNQEADQHSARLFIQSLEGLLPRLLSLSNVEEVDTALQNFASTFCSGMMHSPGFDGNSSLSFQMLMNADSLYT AAHCALLLNLKLSHGDYYRKRPTLAPGVMKDFMKQVQTSGVLMVFSQAWIEELYHQVLDRNMLGEAGYWGSPEDNSLPLITMLTDIDGLE SSAIGGQLMASAATESPFAQSRRIDDSTVAGVAFARYILVGCWKNLIDTLSTPLTGRMAGSSKGLAFILGAEGIKEQNQKERDAICMSLD GLRKAARLSCALGVAANCASALAQMAAASCVQEEKEEREAQEPSDAITQVKLKVEQKLEQIGKVQGVWLHTAHVLCMEAILSVGLEMGSH NPDCWPHVFRVCEYVGTLEHNHFSDGASQPPLTISQPQKATGSAGLLGDPECEGSPPEHSPEQGRSLSTAPVVQPLSIQDLVREGSRGRA SDFRGGSLMSGSSAAKVVLTLSTQADRLFEDATDKLNLMALGGFLYQLKKASQSQLFHSVTDTVDYSLAMPGEVKSTQDRKSALHLFRLG NAMLRIVRSKARPLLHVMRCWSLVAPHLVEAACHKERHVSQKAVSFIHDILTEVLTDWNEPPHFHFNEALFRPFERIMQLELCDEDVQDQ VVTSIGELVEVCSTQIQSGWRPLFSALETVHGGNKSEMKEYLVGDYSMGKGQAPVFDVFEAFLNTDNIQVFANAATSYIMCLMKFVKGLG EVDCKEIGDCAPAPGAPSTDLCLPALDYLRRCSQLLAKIYKMPLKPIFLSGRLAGLPRRLQEQSASSEDGIESVLSDFDDDTGLIEVWII LLEQLTAAVSNCPRQHQPPTLDLLFELLRDVTKTPGPGFGIYAVVHLLLPVMSVWLRRSHKDHSYWDMASANFKHAIGLSCELVVEHIQS FLHSDIRYESMINTMLKDLFELLVACVAKPTETISRVGCSCIRYVLVTAGPVFTEEMWRLACCALQDAFSATLKPVKDLLGCFHSGTESF SGEGCQVRVAAPSSSPSAEAEYWRIRAMAQQVFMLDTQCSPKTPNNFDHAQSCQLIIELPPDEKPNGHTKKSVSFREIVVSLLSHQVLLQ NLYDILLEEFVKGPSPGEEKTIQVPEAKLAGFLRYISMQNLAVIFDLLLDSYRTAREFDTSPGLKCLLKKVSGIGGAANLYRQSAMSFNI YFHALVCAVLTNQETITAEQVKKVLFEDDERSTDSSQQCSSEDEDIFEETAQVSPPRGKEKRQWRARMPLLSVQPVSNADWVWLVKRLHK LCMELCNNYIQMHLDLENCMEEPPIFKGDPFFILPSFQSESSTPSTGGFSGKETPSEDDRSQSREHMGESLSLKAGGGDLLLPPSPKVEK KDPSRKKEWWENAGNKIYTMAADKTISKLMTEYKKRKQQHNLSAFPKEVKVEKKGEPLGPRGQDSPLLQRPQHLMDQGQMRHSFSAGPEL LRQDKRPRSGSTGSSLSVSVRDAEAQIQAWTNMVLTVLNQIQILPDQTFTALQPAVFPCISQLTCHVTDIRVRQAVREWLGRVGRVYDII -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SKAP2-KIAA1244 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SKAP2-KIAA1244 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SKAP2-KIAA1244 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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