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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SKIV2L2-SCCPDH (FusionGDB2 ID:82139)

Fusion Gene Summary for SKIV2L2-SCCPDH

check button Fusion gene summary
Fusion gene informationFusion gene name: SKIV2L2-SCCPDH
Fusion gene ID: 82139
HgeneTgene
Gene symbol

SKIV2L2

SCCPDH

Gene ID

23517

51097

Gene nameMtr4 exosome RNA helicasesaccharopine dehydrogenase (putative)
SynonymsDob1|KIAA0052|Mtr4|SKIV2L2|fSAP118CGI-49|NET11
Cytomap

5q11.2

1q44

Type of geneprotein-codingprotein-coding
Descriptionexosome RNA helicase MTR4ATP-dependent RNA helicase DOB1ATP-dependent RNA helicase SKIV2L2ATP-dependent helicase SKIV2L2Ski2 like RNA helicase 2TRAMP-like complex helicasefunctional spliceosome-associated protein 118superkiller viralicidic activitysaccharopine dehydrogenase-like oxidoreductaseepididymis secretory sperm binding proteinprobable saccharopine dehydrogenase
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000230640, ENST00000545714, 
ENST00000504388, 		ENST00000366510, 
Fusion gene scores* DoF score34 X 12 X 8=32648 X 11 X 7=616
# samples 1511
** MAII scorelog2(15/3264*10)=-4.44360665147561
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/616*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SKIV2L2 [Title/Abstract] AND SCCPDH [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSKIV2L2(54711960)-SCCPDH(246890194), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSKIV2L2

GO:0006401

RNA catabolic process

29906447


check buttonFusion gene breakpoints across SKIV2L2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SCCPDH (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-EJ-5519-01ASKIV2L2chr5

54711959

+SCCPDHchr1

246890193

+
ChimerDB4PRADTCGA-EJ-5519-01ASKIV2L2chr5

54711960

-SCCPDHchr1

246890194

+
ChimerDB4PRADTCGA-EJ-5519-01ASKIV2L2chr5

54711960

+SCCPDHchr1

246890194

+
ChimerDB4PRADTCGA-EJ-5519SKIV2L2chr5

54711960

+SCCPDHchr1

246890193

+
ChimerDB4PRADTCGA-EJ-5519SKIV2L2chr5

54711960

+SCCPDHchr1

246890194

+


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Fusion Gene ORF analysis for SKIV2L2-SCCPDH

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000230640ENST00000366510SKIV2L2chr5

54711959

+SCCPDHchr1

246890193

+
In-frameENST00000230640ENST00000366510SKIV2L2chr5

54711960

+SCCPDHchr1

246890194

+
In-frameENST00000230640ENST00000366510SKIV2L2chr5

54711960

+SCCPDHchr1

246890193

+
In-frameENST00000545714ENST00000366510SKIV2L2chr5

54711959

+SCCPDHchr1

246890193

+
In-frameENST00000545714ENST00000366510SKIV2L2chr5

54711960

+SCCPDHchr1

246890194

+
In-frameENST00000545714ENST00000366510SKIV2L2chr5

54711960

+SCCPDHchr1

246890193

+
intron-3CDSENST00000504388ENST00000366510SKIV2L2chr5

54711959

+SCCPDHchr1

246890193

+
intron-3CDSENST00000504388ENST00000366510SKIV2L2chr5

54711960

+SCCPDHchr1

246890194

+
intron-3CDSENST00000504388ENST00000366510SKIV2L2chr5

54711960

+SCCPDHchr1

246890193

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000230640SKIV2L2chr554711960+ENST00000366510SCCPDHchr1246890194+5162322523343241363
ENST00000545714SKIV2L2chr554711960+ENST00000366510SCCPDHchr1246890194+4716277911138781255
ENST00000230640SKIV2L2chr554711960+ENST00000366510SCCPDHchr1246890193+5162322523343241363
ENST00000545714SKIV2L2chr554711960+ENST00000366510SCCPDHchr1246890193+4716277911138781255
ENST00000230640SKIV2L2chr554711959+ENST00000366510SCCPDHchr1246890193+5162322523343241363
ENST00000545714SKIV2L2chr554711959+ENST00000366510SCCPDHchr1246890193+4716277911138781255

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000230640ENST00000366510SKIV2L2chr554711960+SCCPDHchr1246890194+0.0002230930.9997769
ENST00000545714ENST00000366510SKIV2L2chr554711960+SCCPDHchr1246890194+0.0002029110.99979717
ENST00000230640ENST00000366510SKIV2L2chr554711960+SCCPDHchr1246890193+0.0002230930.9997769
ENST00000545714ENST00000366510SKIV2L2chr554711960+SCCPDHchr1246890193+0.0002029110.99979717
ENST00000230640ENST00000366510SKIV2L2chr554711959+SCCPDHchr1246890193+0.0002230930.9997769
ENST00000545714ENST00000366510SKIV2L2chr554711959+SCCPDHchr1246890193+0.0002029110.99979717

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Fusion Genomic Features for SKIV2L2-SCCPDH


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SKIV2L2chr554711960+SCCPDHchr1246890193+7.32E-050.9999268
SKIV2L2chr554711960+SCCPDHchr1246890193+7.32E-050.9999268
SKIV2L2chr554711960+SCCPDHchr1246890193+7.32E-050.9999268
SKIV2L2chr554711960+SCCPDHchr1246890193+7.32E-050.9999268

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SKIV2L2-SCCPDH


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:54711960/chr1:246890194)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSKIV2L2chr5:54711959chr1:246890193ENST00000230640+2527148_3049901043.0DomainHelicase ATP-binding
HgeneSKIV2L2chr5:54711959chr1:246890193ENST00000230640+2527405_5779901043.0DomainHelicase C-terminal
HgeneSKIV2L2chr5:54711960chr1:246890193ENST00000230640+2527148_3049901043.0DomainHelicase ATP-binding
HgeneSKIV2L2chr5:54711960chr1:246890193ENST00000230640+2527405_5779901043.0DomainHelicase C-terminal
HgeneSKIV2L2chr5:54711960chr1:246890194ENST00000230640+2527148_3049901043.0DomainHelicase ATP-binding
HgeneSKIV2L2chr5:54711960chr1:246890194ENST00000230640+2527405_5779901043.0DomainHelicase C-terminal
HgeneSKIV2L2chr5:54711959chr1:246890193ENST00000230640+2527252_2559901043.0MotifNote=DEIH box
HgeneSKIV2L2chr5:54711960chr1:246890193ENST00000230640+2527252_2559901043.0MotifNote=DEIH box
HgeneSKIV2L2chr5:54711960chr1:246890194ENST00000230640+2527252_2559901043.0MotifNote=DEIH box
HgeneSKIV2L2chr5:54711959chr1:246890193ENST00000230640+2527161_1689901043.0Nucleotide bindingATP
HgeneSKIV2L2chr5:54711960chr1:246890193ENST00000230640+2527161_1689901043.0Nucleotide bindingATP
HgeneSKIV2L2chr5:54711960chr1:246890194ENST00000230640+2527161_1689901043.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for SKIV2L2-SCCPDH


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>82139_82139_1_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711959_ENST00000230640_SCCPDH_chr1_246890193_ENST00000366510_length(transcript)=5162nt_BP=3225nt
GCTGCCTGCCACACGCCAGGCGCCACGCGCCGCCCTCGCTCTTTATCCACTGAGCAGCTTATCCACTTTAGGTCGGAAAGGAAAGGAAAG
AAAAGCAGGAAAAAAAAAAAAAGTCAGGGGAACATTTTTGTCGGCTGCGCGACTCGACTACTTTTGTCTCCTGCGGGCCACTGTTGAGCC
TTCACGAGACGTCACTGTCTTCGGTCGCGGGGCATCGTGGGTAGGAGGGAGATTTGCTCTCACTGCTCCCAAAAATGGCGGACGCATTCG
GAGATGAGCTGTTCAGCGTGTTCGAGGGCGACTCGACCACTGCGGCGGGAACCAAAAAAGACAAGGAAAAGGACAAGGGGAAATGGAAGG
GGCCTCCAGGGTCTGCAGACAAGGCAGGGAAACGTTTTGATGGTAAATTACAATCAGAATCAACTAATAATGGAAAAAATAAGAGAGATG
TAGATTTCGAAGGTACAGATGAACCCATTTTTGGAAAGAAGCCCAGGATAGAAGAGTCAATAACTGAAGACTTAAGTTTGGCAGACCTGA
TGCCCAGAGTCAAGGTACAATCAGTTGAAACTGTTGAAGGGTGTACACATGAGGTTGCACTTCCTGCAGAAGAGGATTATTTACCACTTA
AACCACGAGTTGGAAAAGCTGCTAAGGAATACCCGTTCATTCTTGATGCTTTTCAAAGAGAGGCCATTCAGTGTGTTGACAATAATCAGT
CTGTTCTAGTATCTGCACATACCTCAGCGGGAAAAACAGTATGCGCCGAGTATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGTGTAA
TATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAAATACCGTGAAATGTATGAAGAATTTCAAGATGTTGGTTTGATGACTGGTGATG
TTACTATTAATCCTACGGCATCTTGTCTTGTTATGACCACAGAGATTTTGAGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGAGAAG
TTGCTTGGGTTATATTTGATGAAATTCATTATATGAGAGATTCAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATA
ACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATG
TTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATG
GTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAG
GAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTA
AGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTA
ATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACC
ATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTG
CTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTG
AATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAA
CAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTG
TAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAA
AGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAAT
TGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAG
GAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAG
TAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGA
TGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATA
GACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTC
AAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGG
AAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCC
TACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAG
TGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAA
CAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGC
AGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACT
TAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGAAGACCAACACTGT
CATCTGAAGTTGGAATCATCATCTGTGATATTGCTAATCCAGCCTCGCTTGATGAAATGGCTAAACAGGCAACAGTTGTCCTCAATTGCG
TAGGACCATATCGGTTTTATGGAGAACCTGTAATAAAAGCATGTATTGAAAATGGAGCCAGTTGTATCGACATCAGTGGAGAACCTCAGT
TTCTGGAACTAATGCAACTGAAGTATCATGAGAAAGCTGCAGACAAAGGGGTTTATATCATTGGAAGCAGCGGCTTTGACTCCATTCCAG
CAGATCTGGGAGTAATATATACCAGAAATAAAATGAATGGTACTTTGACTGCTGTGGAAAGTTTCCTGACTATACATTCAGGACCTGAGG
GGTTGAGCATTCATGATGGTACCTGGAAGTCAGCAATTTATGGTTTTGGAGATCAGAGTAATTTGAGAAAACTAAGAAATGTATCAAATC
TGAAACCTGTCCCGCTCATTGGTCCAAAATTGAAGAGAAGGTGGCCAATTTCTTATTGTCGGGAACTCAAAGGTTATTCCATTCCTTTTA
TGGGATCTGATGTGTCTGTTGTAAGGAGGACTCAACGTTACTTGTATGAAAATTTAGAGGAATCACCAGTTCAGTATGCTGCGTATGTAA
CTGTGGGAGGCATCACCTCTGTTATTAAGCTGATGTTTGCAGGACTTTTCTTTTTGTTCTTTGTGAGGTTTGGAATTGGAAGGCAACTTC
TCATAAAATTCCCATGGTTCTTCTCCTTTGGCTATTTTTCAAAACAAGGCCCAACACAAAAACAGATTGATGCTGCCTCATTCACGCTGA
CATTCTTTGGTCAAGGATACAGCCAAGGCACTGGTACAGATAAGAACAAACCAAATATCAAAATTTGTACTCAGGTGAAAGGACCAGAGG
CTGGCTATGTGGCTACCCCCATAGCTATGGTTCAGGCAGCCATGACTCTTCTAAGTGATGCTTCTCATCTGCCTAAGGCGGGCGGGGTCT
TCACACCTGGAGCAGCTTTTTCCAAAACAAAGTTGATTGACAGACTCAACAAACACGGTATTGAGTTTAGTGTTATTAGCAGCTCTGAAG
TCTAAACACTGGAAGAATTAACTGAAGTCATAACGTGCGTGAATTAACAGCTTCTCTATTTGATATTTGAAATTCTTCTGTAAGCCTGTC
TGAGTGTATGTGGAAACGATTGTCAAATCTAAAATATCTATATATTAAAAAGTAGGAAATTGTCCTAGCTTACCCTAAATTTCAAATCTG
AGTTGATTTTGTGATTTTATTGCTTATAACAGAGAACTCATATTTGACATATTTTTTTCATTGATGTGTTCCTGGTAGATTTTCACGAAT
GAGCTGGCAGGTCTAATGGGGGAGGCGGCGTCCCAGTCTGTGTTGCAGCAGCATTCTCATCGGGGGTGCGCACACCATCGTTACTGTCGG
GCAGTAACTGCCGCTTGCCTTGCCGCAGTAGGAGGGAAATCTCACCTTCCTTCCACATACTGTCTTGAGCCTTTGCTAAATTAAACTGCA
CTTTTTGCTATTTTTGCCTAGTTTTTCGCCAATCTACACTGATTTTGGACTGTTACCTAAGTTGAAAAATAAAAGGTTGTCAATCGAATG
GTGGTTTAATGTTTGGACCTGCCGATGTATTTGTATAGTGGTAGAAACATGCTGCTTAAGTGGCCTAACCTGTTTCTTGCCAATAAGTAG
GCTTATCATTTTATCTTTACGTAATTCTATATCTGTGACTAGGTTTTTAAGGATACAGCTTATAAGTTGCTATCAATTTTCACTACCTAA
GCAGAATTTTTCTCTAATTTACTTTTTGTATTTTAACTAGGTTTTACATGGAAGCCCTAAAATAAGGCAAAAGACTTTTTCTTTTGTAAT

>82139_82139_1_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711959_ENST00000230640_SCCPDH_chr1_246890193_ENST00000366510_length(amino acids)=1363AA_BP=997
MLSLLPKMADAFGDELFSVFEGDSTTAAGTKKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNGKNKRDVDFEGTDEPIFGKKPRIE
ESITEDLSLADLMPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEY
AIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERG
VVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDA
GDLAKGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEH
VLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRG
IVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESV
VIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATE
AAKPAKPDEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHR
MYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMF
NGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHIC
KMTDVFEGRPTLSSEVGIIICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASCIDISGEPQFLELMQLKYHEKAADKGV
YIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESFLTIHSGPEGLSIHDGTWKSAIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPIS
YCRELKGYSIPFMGSDVSVVRRTQRYLYENLEESPVQYAAYVTVGGITSVIKLMFAGLFFLFFVRFGIGRQLLIKFPWFFSFGYFSKQGP
TQKQIDAASFTLTFFGQGYSQGTGTDKNKPNIKICTQVKGPEAGYVATPIAMVQAAMTLLSDASHLPKAGGVFTPGAAFSKTKLIDRLNK

--------------------------------------------------------------
>82139_82139_2_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711959_ENST00000545714_SCCPDH_chr1_246890193_ENST00000366510_length(transcript)=4716nt_BP=2779nt
ACTGCTCCCAAAAATGGCGGACGCATTCGGAGATGAGCTGTTCAGCGTGTTCGAGGGCGACTCGACCACTGCGGCGGGAACCAAAAAAGA
CAAGGAAAAGGACAAGGGGAAATGGAAGGGGCCTCCAGGGTCTGCAGACAAGGCAGGGTTGCACTTCCTGCAGAAGAGGATTATTTACCA
CTTAAACCACGAGTTGGAAAAGCTGCTAAGGAATACCCGTTCATTCTTGATGCTTTTCAAAGAGAGGCCATTCAGTGTGTTGACAATAAT
CAGTCTGTTCTAGTATCTGCACATACCTCAGCGGGAAAAACAGTATGCGCCGAGTATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGT
GTAATATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAAATACCGTGAAATGTATGAAGAATTTCAAGATGTTGGTTTGATGACTGGT
GATGTTACTATTAATCCTACGGCATCTTGTCTTGTTATGACCACAGAGATTTTGAGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGA
GAAGTTGCTTGGGTTATATTTGATGAAATTCATTATATGAGAGATTCAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCT
GATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGT
CATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAA
AATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGG
AAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTT
AGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTC
AGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATT
CACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACC
TTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCT
GGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGC
CCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTA
CGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAG
GTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCC
AAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAAT
GAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTAT
GTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGA
GAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGAC
AATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGC
ATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAAT
TTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACA
GTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGA
CGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAG
GCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAA
ATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCT
CACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGAAGACCAACA
CTGTCATCTGAAGTTGGAATCATCATCTGTGATATTGCTAATCCAGCCTCGCTTGATGAAATGGCTAAACAGGCAACAGTTGTCCTCAAT
TGCGTAGGACCATATCGGTTTTATGGAGAACCTGTAATAAAAGCATGTATTGAAAATGGAGCCAGTTGTATCGACATCAGTGGAGAACCT
CAGTTTCTGGAACTAATGCAACTGAAGTATCATGAGAAAGCTGCAGACAAAGGGGTTTATATCATTGGAAGCAGCGGCTTTGACTCCATT
CCAGCAGATCTGGGAGTAATATATACCAGAAATAAAATGAATGGTACTTTGACTGCTGTGGAAAGTTTCCTGACTATACATTCAGGACCT
GAGGGGTTGAGCATTCATGATGGTACCTGGAAGTCAGCAATTTATGGTTTTGGAGATCAGAGTAATTTGAGAAAACTAAGAAATGTATCA
AATCTGAAACCTGTCCCGCTCATTGGTCCAAAATTGAAGAGAAGGTGGCCAATTTCTTATTGTCGGGAACTCAAAGGTTATTCCATTCCT
TTTATGGGATCTGATGTGTCTGTTGTAAGGAGGACTCAACGTTACTTGTATGAAAATTTAGAGGAATCACCAGTTCAGTATGCTGCGTAT
GTAACTGTGGGAGGCATCACCTCTGTTATTAAGCTGATGTTTGCAGGACTTTTCTTTTTGTTCTTTGTGAGGTTTGGAATTGGAAGGCAA
CTTCTCATAAAATTCCCATGGTTCTTCTCCTTTGGCTATTTTTCAAAACAAGGCCCAACACAAAAACAGATTGATGCTGCCTCATTCACG
CTGACATTCTTTGGTCAAGGATACAGCCAAGGCACTGGTACAGATAAGAACAAACCAAATATCAAAATTTGTACTCAGGTGAAAGGACCA
GAGGCTGGCTATGTGGCTACCCCCATAGCTATGGTTCAGGCAGCCATGACTCTTCTAAGTGATGCTTCTCATCTGCCTAAGGCGGGCGGG
GTCTTCACACCTGGAGCAGCTTTTTCCAAAACAAAGTTGATTGACAGACTCAACAAACACGGTATTGAGTTTAGTGTTATTAGCAGCTCT
GAAGTCTAAACACTGGAAGAATTAACTGAAGTCATAACGTGCGTGAATTAACAGCTTCTCTATTTGATATTTGAAATTCTTCTGTAAGCC
TGTCTGAGTGTATGTGGAAACGATTGTCAAATCTAAAATATCTATATATTAAAAAGTAGGAAATTGTCCTAGCTTACCCTAAATTTCAAA
TCTGAGTTGATTTTGTGATTTTATTGCTTATAACAGAGAACTCATATTTGACATATTTTTTTCATTGATGTGTTCCTGGTAGATTTTCAC
GAATGAGCTGGCAGGTCTAATGGGGGAGGCGGCGTCCCAGTCTGTGTTGCAGCAGCATTCTCATCGGGGGTGCGCACACCATCGTTACTG
TCGGGCAGTAACTGCCGCTTGCCTTGCCGCAGTAGGAGGGAAATCTCACCTTCCTTCCACATACTGTCTTGAGCCTTTGCTAAATTAAAC
TGCACTTTTTGCTATTTTTGCCTAGTTTTTCGCCAATCTACACTGATTTTGGACTGTTACCTAAGTTGAAAAATAAAAGGTTGTCAATCG
AATGGTGGTTTAATGTTTGGACCTGCCGATGTATTTGTATAGTGGTAGAAACATGCTGCTTAAGTGGCCTAACCTGTTTCTTGCCAATAA
GTAGGCTTATCATTTTATCTTTACGTAATTCTATATCTGTGACTAGGTTTTTAAGGATACAGCTTATAAGTTGCTATCAATTTTCACTAC
CTAAGCAGAATTTTTCTCTAATTTACTTTTTGTATTTTAACTAGGTTTTACATGGAAGCCCTAAAATAAGGCAAAAGACTTTTTCTTTTG

>82139_82139_2_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711959_ENST00000545714_SCCPDH_chr1_246890193_ENST00000366510_length(amino acids)=1255AA_BP=889
MEGASRVCRQGRVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPI
KALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVF
LSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGP
SNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLP
ILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQL
LKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIE
EYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPV
LVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTL
CEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSC
FVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGRPTLSSEVGI
IICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASCIDISGEPQFLELMQLKYHEKAADKGVYIIGSSGFDSIPADLGVI
YTRNKMNGTLTAVESFLTIHSGPEGLSIHDGTWKSAIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPISYCRELKGYSIPFMGSDVS
VVRRTQRYLYENLEESPVQYAAYVTVGGITSVIKLMFAGLFFLFFVRFGIGRQLLIKFPWFFSFGYFSKQGPTQKQIDAASFTLTFFGQG

--------------------------------------------------------------
>82139_82139_3_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711960_ENST00000230640_SCCPDH_chr1_246890193_ENST00000366510_length(transcript)=5162nt_BP=3225nt
GCTGCCTGCCACACGCCAGGCGCCACGCGCCGCCCTCGCTCTTTATCCACTGAGCAGCTTATCCACTTTAGGTCGGAAAGGAAAGGAAAG
AAAAGCAGGAAAAAAAAAAAAAGTCAGGGGAACATTTTTGTCGGCTGCGCGACTCGACTACTTTTGTCTCCTGCGGGCCACTGTTGAGCC
TTCACGAGACGTCACTGTCTTCGGTCGCGGGGCATCGTGGGTAGGAGGGAGATTTGCTCTCACTGCTCCCAAAAATGGCGGACGCATTCG
GAGATGAGCTGTTCAGCGTGTTCGAGGGCGACTCGACCACTGCGGCGGGAACCAAAAAAGACAAGGAAAAGGACAAGGGGAAATGGAAGG
GGCCTCCAGGGTCTGCAGACAAGGCAGGGAAACGTTTTGATGGTAAATTACAATCAGAATCAACTAATAATGGAAAAAATAAGAGAGATG
TAGATTTCGAAGGTACAGATGAACCCATTTTTGGAAAGAAGCCCAGGATAGAAGAGTCAATAACTGAAGACTTAAGTTTGGCAGACCTGA
TGCCCAGAGTCAAGGTACAATCAGTTGAAACTGTTGAAGGGTGTACACATGAGGTTGCACTTCCTGCAGAAGAGGATTATTTACCACTTA
AACCACGAGTTGGAAAAGCTGCTAAGGAATACCCGTTCATTCTTGATGCTTTTCAAAGAGAGGCCATTCAGTGTGTTGACAATAATCAGT
CTGTTCTAGTATCTGCACATACCTCAGCGGGAAAAACAGTATGCGCCGAGTATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGTGTAA
TATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAAATACCGTGAAATGTATGAAGAATTTCAAGATGTTGGTTTGATGACTGGTGATG
TTACTATTAATCCTACGGCATCTTGTCTTGTTATGACCACAGAGATTTTGAGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGAGAAG
TTGCTTGGGTTATATTTGATGAAATTCATTATATGAGAGATTCAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATA
ACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATG
TTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATG
GTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAG
GAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTA
AGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTA
ATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACC
ATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTG
CTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTG
AATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAA
CAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTG
TAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAA
AGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAAT
TGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAG
GAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAG
TAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGA
TGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATA
GACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTC
AAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGG
AAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCC
TACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAG
TGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAA
CAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGC
AGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACT
TAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGAAGACCAACACTGT
CATCTGAAGTTGGAATCATCATCTGTGATATTGCTAATCCAGCCTCGCTTGATGAAATGGCTAAACAGGCAACAGTTGTCCTCAATTGCG
TAGGACCATATCGGTTTTATGGAGAACCTGTAATAAAAGCATGTATTGAAAATGGAGCCAGTTGTATCGACATCAGTGGAGAACCTCAGT
TTCTGGAACTAATGCAACTGAAGTATCATGAGAAAGCTGCAGACAAAGGGGTTTATATCATTGGAAGCAGCGGCTTTGACTCCATTCCAG
CAGATCTGGGAGTAATATATACCAGAAATAAAATGAATGGTACTTTGACTGCTGTGGAAAGTTTCCTGACTATACATTCAGGACCTGAGG
GGTTGAGCATTCATGATGGTACCTGGAAGTCAGCAATTTATGGTTTTGGAGATCAGAGTAATTTGAGAAAACTAAGAAATGTATCAAATC
TGAAACCTGTCCCGCTCATTGGTCCAAAATTGAAGAGAAGGTGGCCAATTTCTTATTGTCGGGAACTCAAAGGTTATTCCATTCCTTTTA
TGGGATCTGATGTGTCTGTTGTAAGGAGGACTCAACGTTACTTGTATGAAAATTTAGAGGAATCACCAGTTCAGTATGCTGCGTATGTAA
CTGTGGGAGGCATCACCTCTGTTATTAAGCTGATGTTTGCAGGACTTTTCTTTTTGTTCTTTGTGAGGTTTGGAATTGGAAGGCAACTTC
TCATAAAATTCCCATGGTTCTTCTCCTTTGGCTATTTTTCAAAACAAGGCCCAACACAAAAACAGATTGATGCTGCCTCATTCACGCTGA
CATTCTTTGGTCAAGGATACAGCCAAGGCACTGGTACAGATAAGAACAAACCAAATATCAAAATTTGTACTCAGGTGAAAGGACCAGAGG
CTGGCTATGTGGCTACCCCCATAGCTATGGTTCAGGCAGCCATGACTCTTCTAAGTGATGCTTCTCATCTGCCTAAGGCGGGCGGGGTCT
TCACACCTGGAGCAGCTTTTTCCAAAACAAAGTTGATTGACAGACTCAACAAACACGGTATTGAGTTTAGTGTTATTAGCAGCTCTGAAG
TCTAAACACTGGAAGAATTAACTGAAGTCATAACGTGCGTGAATTAACAGCTTCTCTATTTGATATTTGAAATTCTTCTGTAAGCCTGTC
TGAGTGTATGTGGAAACGATTGTCAAATCTAAAATATCTATATATTAAAAAGTAGGAAATTGTCCTAGCTTACCCTAAATTTCAAATCTG
AGTTGATTTTGTGATTTTATTGCTTATAACAGAGAACTCATATTTGACATATTTTTTTCATTGATGTGTTCCTGGTAGATTTTCACGAAT
GAGCTGGCAGGTCTAATGGGGGAGGCGGCGTCCCAGTCTGTGTTGCAGCAGCATTCTCATCGGGGGTGCGCACACCATCGTTACTGTCGG
GCAGTAACTGCCGCTTGCCTTGCCGCAGTAGGAGGGAAATCTCACCTTCCTTCCACATACTGTCTTGAGCCTTTGCTAAATTAAACTGCA
CTTTTTGCTATTTTTGCCTAGTTTTTCGCCAATCTACACTGATTTTGGACTGTTACCTAAGTTGAAAAATAAAAGGTTGTCAATCGAATG
GTGGTTTAATGTTTGGACCTGCCGATGTATTTGTATAGTGGTAGAAACATGCTGCTTAAGTGGCCTAACCTGTTTCTTGCCAATAAGTAG
GCTTATCATTTTATCTTTACGTAATTCTATATCTGTGACTAGGTTTTTAAGGATACAGCTTATAAGTTGCTATCAATTTTCACTACCTAA
GCAGAATTTTTCTCTAATTTACTTTTTGTATTTTAACTAGGTTTTACATGGAAGCCCTAAAATAAGGCAAAAGACTTTTTCTTTTGTAAT

>82139_82139_3_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711960_ENST00000230640_SCCPDH_chr1_246890193_ENST00000366510_length(amino acids)=1363AA_BP=997
MLSLLPKMADAFGDELFSVFEGDSTTAAGTKKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNGKNKRDVDFEGTDEPIFGKKPRIE
ESITEDLSLADLMPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEY
AIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERG
VVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDA
GDLAKGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEH
VLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRG
IVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESV
VIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATE
AAKPAKPDEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHR
MYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMF
NGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHIC
KMTDVFEGRPTLSSEVGIIICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASCIDISGEPQFLELMQLKYHEKAADKGV
YIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESFLTIHSGPEGLSIHDGTWKSAIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPIS
YCRELKGYSIPFMGSDVSVVRRTQRYLYENLEESPVQYAAYVTVGGITSVIKLMFAGLFFLFFVRFGIGRQLLIKFPWFFSFGYFSKQGP
TQKQIDAASFTLTFFGQGYSQGTGTDKNKPNIKICTQVKGPEAGYVATPIAMVQAAMTLLSDASHLPKAGGVFTPGAAFSKTKLIDRLNK

--------------------------------------------------------------
>82139_82139_4_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711960_ENST00000230640_SCCPDH_chr1_246890194_ENST00000366510_length(transcript)=5162nt_BP=3225nt
GCTGCCTGCCACACGCCAGGCGCCACGCGCCGCCCTCGCTCTTTATCCACTGAGCAGCTTATCCACTTTAGGTCGGAAAGGAAAGGAAAG
AAAAGCAGGAAAAAAAAAAAAAGTCAGGGGAACATTTTTGTCGGCTGCGCGACTCGACTACTTTTGTCTCCTGCGGGCCACTGTTGAGCC
TTCACGAGACGTCACTGTCTTCGGTCGCGGGGCATCGTGGGTAGGAGGGAGATTTGCTCTCACTGCTCCCAAAAATGGCGGACGCATTCG
GAGATGAGCTGTTCAGCGTGTTCGAGGGCGACTCGACCACTGCGGCGGGAACCAAAAAAGACAAGGAAAAGGACAAGGGGAAATGGAAGG
GGCCTCCAGGGTCTGCAGACAAGGCAGGGAAACGTTTTGATGGTAAATTACAATCAGAATCAACTAATAATGGAAAAAATAAGAGAGATG
TAGATTTCGAAGGTACAGATGAACCCATTTTTGGAAAGAAGCCCAGGATAGAAGAGTCAATAACTGAAGACTTAAGTTTGGCAGACCTGA
TGCCCAGAGTCAAGGTACAATCAGTTGAAACTGTTGAAGGGTGTACACATGAGGTTGCACTTCCTGCAGAAGAGGATTATTTACCACTTA
AACCACGAGTTGGAAAAGCTGCTAAGGAATACCCGTTCATTCTTGATGCTTTTCAAAGAGAGGCCATTCAGTGTGTTGACAATAATCAGT
CTGTTCTAGTATCTGCACATACCTCAGCGGGAAAAACAGTATGCGCCGAGTATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGTGTAA
TATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAAATACCGTGAAATGTATGAAGAATTTCAAGATGTTGGTTTGATGACTGGTGATG
TTACTATTAATCCTACGGCATCTTGTCTTGTTATGACCACAGAGATTTTGAGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGAGAAG
TTGCTTGGGTTATATTTGATGAAATTCATTATATGAGAGATTCAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATA
ACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATG
TTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATG
GTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAG
GAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTA
AGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTA
ATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACC
ATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTG
CTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTG
AATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAA
CAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTG
TAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAA
AGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAAT
TGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAG
GAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAG
TAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGA
TGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATA
GACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTC
AAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGG
AAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCC
TACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAG
TGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAA
CAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGC
AGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACT
TAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGAAGACCAACACTGT
CATCTGAAGTTGGAATCATCATCTGTGATATTGCTAATCCAGCCTCGCTTGATGAAATGGCTAAACAGGCAACAGTTGTCCTCAATTGCG
TAGGACCATATCGGTTTTATGGAGAACCTGTAATAAAAGCATGTATTGAAAATGGAGCCAGTTGTATCGACATCAGTGGAGAACCTCAGT
TTCTGGAACTAATGCAACTGAAGTATCATGAGAAAGCTGCAGACAAAGGGGTTTATATCATTGGAAGCAGCGGCTTTGACTCCATTCCAG
CAGATCTGGGAGTAATATATACCAGAAATAAAATGAATGGTACTTTGACTGCTGTGGAAAGTTTCCTGACTATACATTCAGGACCTGAGG
GGTTGAGCATTCATGATGGTACCTGGAAGTCAGCAATTTATGGTTTTGGAGATCAGAGTAATTTGAGAAAACTAAGAAATGTATCAAATC
TGAAACCTGTCCCGCTCATTGGTCCAAAATTGAAGAGAAGGTGGCCAATTTCTTATTGTCGGGAACTCAAAGGTTATTCCATTCCTTTTA
TGGGATCTGATGTGTCTGTTGTAAGGAGGACTCAACGTTACTTGTATGAAAATTTAGAGGAATCACCAGTTCAGTATGCTGCGTATGTAA
CTGTGGGAGGCATCACCTCTGTTATTAAGCTGATGTTTGCAGGACTTTTCTTTTTGTTCTTTGTGAGGTTTGGAATTGGAAGGCAACTTC
TCATAAAATTCCCATGGTTCTTCTCCTTTGGCTATTTTTCAAAACAAGGCCCAACACAAAAACAGATTGATGCTGCCTCATTCACGCTGA
CATTCTTTGGTCAAGGATACAGCCAAGGCACTGGTACAGATAAGAACAAACCAAATATCAAAATTTGTACTCAGGTGAAAGGACCAGAGG
CTGGCTATGTGGCTACCCCCATAGCTATGGTTCAGGCAGCCATGACTCTTCTAAGTGATGCTTCTCATCTGCCTAAGGCGGGCGGGGTCT
TCACACCTGGAGCAGCTTTTTCCAAAACAAAGTTGATTGACAGACTCAACAAACACGGTATTGAGTTTAGTGTTATTAGCAGCTCTGAAG
TCTAAACACTGGAAGAATTAACTGAAGTCATAACGTGCGTGAATTAACAGCTTCTCTATTTGATATTTGAAATTCTTCTGTAAGCCTGTC
TGAGTGTATGTGGAAACGATTGTCAAATCTAAAATATCTATATATTAAAAAGTAGGAAATTGTCCTAGCTTACCCTAAATTTCAAATCTG
AGTTGATTTTGTGATTTTATTGCTTATAACAGAGAACTCATATTTGACATATTTTTTTCATTGATGTGTTCCTGGTAGATTTTCACGAAT
GAGCTGGCAGGTCTAATGGGGGAGGCGGCGTCCCAGTCTGTGTTGCAGCAGCATTCTCATCGGGGGTGCGCACACCATCGTTACTGTCGG
GCAGTAACTGCCGCTTGCCTTGCCGCAGTAGGAGGGAAATCTCACCTTCCTTCCACATACTGTCTTGAGCCTTTGCTAAATTAAACTGCA
CTTTTTGCTATTTTTGCCTAGTTTTTCGCCAATCTACACTGATTTTGGACTGTTACCTAAGTTGAAAAATAAAAGGTTGTCAATCGAATG
GTGGTTTAATGTTTGGACCTGCCGATGTATTTGTATAGTGGTAGAAACATGCTGCTTAAGTGGCCTAACCTGTTTCTTGCCAATAAGTAG
GCTTATCATTTTATCTTTACGTAATTCTATATCTGTGACTAGGTTTTTAAGGATACAGCTTATAAGTTGCTATCAATTTTCACTACCTAA
GCAGAATTTTTCTCTAATTTACTTTTTGTATTTTAACTAGGTTTTACATGGAAGCCCTAAAATAAGGCAAAAGACTTTTTCTTTTGTAAT

>82139_82139_4_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711960_ENST00000230640_SCCPDH_chr1_246890194_ENST00000366510_length(amino acids)=1363AA_BP=997
MLSLLPKMADAFGDELFSVFEGDSTTAAGTKKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNGKNKRDVDFEGTDEPIFGKKPRIE
ESITEDLSLADLMPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEY
AIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERG
VVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDA
GDLAKGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEH
VLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRG
IVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESV
VIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATE
AAKPAKPDEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHR
MYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMF
NGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHIC
KMTDVFEGRPTLSSEVGIIICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASCIDISGEPQFLELMQLKYHEKAADKGV
YIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESFLTIHSGPEGLSIHDGTWKSAIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPIS
YCRELKGYSIPFMGSDVSVVRRTQRYLYENLEESPVQYAAYVTVGGITSVIKLMFAGLFFLFFVRFGIGRQLLIKFPWFFSFGYFSKQGP
TQKQIDAASFTLTFFGQGYSQGTGTDKNKPNIKICTQVKGPEAGYVATPIAMVQAAMTLLSDASHLPKAGGVFTPGAAFSKTKLIDRLNK

--------------------------------------------------------------
>82139_82139_5_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711960_ENST00000545714_SCCPDH_chr1_246890193_ENST00000366510_length(transcript)=4716nt_BP=2779nt
ACTGCTCCCAAAAATGGCGGACGCATTCGGAGATGAGCTGTTCAGCGTGTTCGAGGGCGACTCGACCACTGCGGCGGGAACCAAAAAAGA
CAAGGAAAAGGACAAGGGGAAATGGAAGGGGCCTCCAGGGTCTGCAGACAAGGCAGGGTTGCACTTCCTGCAGAAGAGGATTATTTACCA
CTTAAACCACGAGTTGGAAAAGCTGCTAAGGAATACCCGTTCATTCTTGATGCTTTTCAAAGAGAGGCCATTCAGTGTGTTGACAATAAT
CAGTCTGTTCTAGTATCTGCACATACCTCAGCGGGAAAAACAGTATGCGCCGAGTATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGT
GTAATATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAAATACCGTGAAATGTATGAAGAATTTCAAGATGTTGGTTTGATGACTGGT
GATGTTACTATTAATCCTACGGCATCTTGTCTTGTTATGACCACAGAGATTTTGAGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGA
GAAGTTGCTTGGGTTATATTTGATGAAATTCATTATATGAGAGATTCAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCT
GATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGT
CATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAA
AATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGG
AAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTT
AGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTC
AGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATT
CACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACC
TTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCT
GGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGC
CCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTA
CGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAG
GTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCC
AAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAAT
GAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTAT
GTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGA
GAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGAC
AATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGC
ATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAAT
TTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACA
GTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGA
CGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAG
GCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAA
ATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCT
CACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGAAGACCAACA
CTGTCATCTGAAGTTGGAATCATCATCTGTGATATTGCTAATCCAGCCTCGCTTGATGAAATGGCTAAACAGGCAACAGTTGTCCTCAAT
TGCGTAGGACCATATCGGTTTTATGGAGAACCTGTAATAAAAGCATGTATTGAAAATGGAGCCAGTTGTATCGACATCAGTGGAGAACCT
CAGTTTCTGGAACTAATGCAACTGAAGTATCATGAGAAAGCTGCAGACAAAGGGGTTTATATCATTGGAAGCAGCGGCTTTGACTCCATT
CCAGCAGATCTGGGAGTAATATATACCAGAAATAAAATGAATGGTACTTTGACTGCTGTGGAAAGTTTCCTGACTATACATTCAGGACCT
GAGGGGTTGAGCATTCATGATGGTACCTGGAAGTCAGCAATTTATGGTTTTGGAGATCAGAGTAATTTGAGAAAACTAAGAAATGTATCA
AATCTGAAACCTGTCCCGCTCATTGGTCCAAAATTGAAGAGAAGGTGGCCAATTTCTTATTGTCGGGAACTCAAAGGTTATTCCATTCCT
TTTATGGGATCTGATGTGTCTGTTGTAAGGAGGACTCAACGTTACTTGTATGAAAATTTAGAGGAATCACCAGTTCAGTATGCTGCGTAT
GTAACTGTGGGAGGCATCACCTCTGTTATTAAGCTGATGTTTGCAGGACTTTTCTTTTTGTTCTTTGTGAGGTTTGGAATTGGAAGGCAA
CTTCTCATAAAATTCCCATGGTTCTTCTCCTTTGGCTATTTTTCAAAACAAGGCCCAACACAAAAACAGATTGATGCTGCCTCATTCACG
CTGACATTCTTTGGTCAAGGATACAGCCAAGGCACTGGTACAGATAAGAACAAACCAAATATCAAAATTTGTACTCAGGTGAAAGGACCA
GAGGCTGGCTATGTGGCTACCCCCATAGCTATGGTTCAGGCAGCCATGACTCTTCTAAGTGATGCTTCTCATCTGCCTAAGGCGGGCGGG
GTCTTCACACCTGGAGCAGCTTTTTCCAAAACAAAGTTGATTGACAGACTCAACAAACACGGTATTGAGTTTAGTGTTATTAGCAGCTCT
GAAGTCTAAACACTGGAAGAATTAACTGAAGTCATAACGTGCGTGAATTAACAGCTTCTCTATTTGATATTTGAAATTCTTCTGTAAGCC
TGTCTGAGTGTATGTGGAAACGATTGTCAAATCTAAAATATCTATATATTAAAAAGTAGGAAATTGTCCTAGCTTACCCTAAATTTCAAA
TCTGAGTTGATTTTGTGATTTTATTGCTTATAACAGAGAACTCATATTTGACATATTTTTTTCATTGATGTGTTCCTGGTAGATTTTCAC
GAATGAGCTGGCAGGTCTAATGGGGGAGGCGGCGTCCCAGTCTGTGTTGCAGCAGCATTCTCATCGGGGGTGCGCACACCATCGTTACTG
TCGGGCAGTAACTGCCGCTTGCCTTGCCGCAGTAGGAGGGAAATCTCACCTTCCTTCCACATACTGTCTTGAGCCTTTGCTAAATTAAAC
TGCACTTTTTGCTATTTTTGCCTAGTTTTTCGCCAATCTACACTGATTTTGGACTGTTACCTAAGTTGAAAAATAAAAGGTTGTCAATCG
AATGGTGGTTTAATGTTTGGACCTGCCGATGTATTTGTATAGTGGTAGAAACATGCTGCTTAAGTGGCCTAACCTGTTTCTTGCCAATAA
GTAGGCTTATCATTTTATCTTTACGTAATTCTATATCTGTGACTAGGTTTTTAAGGATACAGCTTATAAGTTGCTATCAATTTTCACTAC
CTAAGCAGAATTTTTCTCTAATTTACTTTTTGTATTTTAACTAGGTTTTACATGGAAGCCCTAAAATAAGGCAAAAGACTTTTTCTTTTG

>82139_82139_5_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711960_ENST00000545714_SCCPDH_chr1_246890193_ENST00000366510_length(amino acids)=1255AA_BP=889
MEGASRVCRQGRVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPI
KALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVF
LSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGP
SNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLP
ILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQL
LKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIE
EYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPV
LVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTL
CEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSC
FVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGRPTLSSEVGI
IICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASCIDISGEPQFLELMQLKYHEKAADKGVYIIGSSGFDSIPADLGVI
YTRNKMNGTLTAVESFLTIHSGPEGLSIHDGTWKSAIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPISYCRELKGYSIPFMGSDVS
VVRRTQRYLYENLEESPVQYAAYVTVGGITSVIKLMFAGLFFLFFVRFGIGRQLLIKFPWFFSFGYFSKQGPTQKQIDAASFTLTFFGQG

--------------------------------------------------------------
>82139_82139_6_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711960_ENST00000545714_SCCPDH_chr1_246890194_ENST00000366510_length(transcript)=4716nt_BP=2779nt
ACTGCTCCCAAAAATGGCGGACGCATTCGGAGATGAGCTGTTCAGCGTGTTCGAGGGCGACTCGACCACTGCGGCGGGAACCAAAAAAGA
CAAGGAAAAGGACAAGGGGAAATGGAAGGGGCCTCCAGGGTCTGCAGACAAGGCAGGGTTGCACTTCCTGCAGAAGAGGATTATTTACCA
CTTAAACCACGAGTTGGAAAAGCTGCTAAGGAATACCCGTTCATTCTTGATGCTTTTCAAAGAGAGGCCATTCAGTGTGTTGACAATAAT
CAGTCTGTTCTAGTATCTGCACATACCTCAGCGGGAAAAACAGTATGCGCCGAGTATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGT
GTAATATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAAATACCGTGAAATGTATGAAGAATTTCAAGATGTTGGTTTGATGACTGGT
GATGTTACTATTAATCCTACGGCATCTTGTCTTGTTATGACCACAGAGATTTTGAGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGA
GAAGTTGCTTGGGTTATATTTGATGAAATTCATTATATGAGAGATTCAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCT
GATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGT
CATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAA
AATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGG
AAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTT
AGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTC
AGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATT
CACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACC
TTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCT
GGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGC
CCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTA
CGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAG
GTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCC
AAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAAT
GAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTAT
GTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGA
GAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGAC
AATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGC
ATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAAT
TTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACA
GTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGA
CGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAG
GCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAA
ATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCT
CACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGAAGACCAACA
CTGTCATCTGAAGTTGGAATCATCATCTGTGATATTGCTAATCCAGCCTCGCTTGATGAAATGGCTAAACAGGCAACAGTTGTCCTCAAT
TGCGTAGGACCATATCGGTTTTATGGAGAACCTGTAATAAAAGCATGTATTGAAAATGGAGCCAGTTGTATCGACATCAGTGGAGAACCT
CAGTTTCTGGAACTAATGCAACTGAAGTATCATGAGAAAGCTGCAGACAAAGGGGTTTATATCATTGGAAGCAGCGGCTTTGACTCCATT
CCAGCAGATCTGGGAGTAATATATACCAGAAATAAAATGAATGGTACTTTGACTGCTGTGGAAAGTTTCCTGACTATACATTCAGGACCT
GAGGGGTTGAGCATTCATGATGGTACCTGGAAGTCAGCAATTTATGGTTTTGGAGATCAGAGTAATTTGAGAAAACTAAGAAATGTATCA
AATCTGAAACCTGTCCCGCTCATTGGTCCAAAATTGAAGAGAAGGTGGCCAATTTCTTATTGTCGGGAACTCAAAGGTTATTCCATTCCT
TTTATGGGATCTGATGTGTCTGTTGTAAGGAGGACTCAACGTTACTTGTATGAAAATTTAGAGGAATCACCAGTTCAGTATGCTGCGTAT
GTAACTGTGGGAGGCATCACCTCTGTTATTAAGCTGATGTTTGCAGGACTTTTCTTTTTGTTCTTTGTGAGGTTTGGAATTGGAAGGCAA
CTTCTCATAAAATTCCCATGGTTCTTCTCCTTTGGCTATTTTTCAAAACAAGGCCCAACACAAAAACAGATTGATGCTGCCTCATTCACG
CTGACATTCTTTGGTCAAGGATACAGCCAAGGCACTGGTACAGATAAGAACAAACCAAATATCAAAATTTGTACTCAGGTGAAAGGACCA
GAGGCTGGCTATGTGGCTACCCCCATAGCTATGGTTCAGGCAGCCATGACTCTTCTAAGTGATGCTTCTCATCTGCCTAAGGCGGGCGGG
GTCTTCACACCTGGAGCAGCTTTTTCCAAAACAAAGTTGATTGACAGACTCAACAAACACGGTATTGAGTTTAGTGTTATTAGCAGCTCT
GAAGTCTAAACACTGGAAGAATTAACTGAAGTCATAACGTGCGTGAATTAACAGCTTCTCTATTTGATATTTGAAATTCTTCTGTAAGCC
TGTCTGAGTGTATGTGGAAACGATTGTCAAATCTAAAATATCTATATATTAAAAAGTAGGAAATTGTCCTAGCTTACCCTAAATTTCAAA
TCTGAGTTGATTTTGTGATTTTATTGCTTATAACAGAGAACTCATATTTGACATATTTTTTTCATTGATGTGTTCCTGGTAGATTTTCAC
GAATGAGCTGGCAGGTCTAATGGGGGAGGCGGCGTCCCAGTCTGTGTTGCAGCAGCATTCTCATCGGGGGTGCGCACACCATCGTTACTG
TCGGGCAGTAACTGCCGCTTGCCTTGCCGCAGTAGGAGGGAAATCTCACCTTCCTTCCACATACTGTCTTGAGCCTTTGCTAAATTAAAC
TGCACTTTTTGCTATTTTTGCCTAGTTTTTCGCCAATCTACACTGATTTTGGACTGTTACCTAAGTTGAAAAATAAAAGGTTGTCAATCG
AATGGTGGTTTAATGTTTGGACCTGCCGATGTATTTGTATAGTGGTAGAAACATGCTGCTTAAGTGGCCTAACCTGTTTCTTGCCAATAA
GTAGGCTTATCATTTTATCTTTACGTAATTCTATATCTGTGACTAGGTTTTTAAGGATACAGCTTATAAGTTGCTATCAATTTTCACTAC
CTAAGCAGAATTTTTCTCTAATTTACTTTTTGTATTTTAACTAGGTTTTACATGGAAGCCCTAAAATAAGGCAAAAGACTTTTTCTTTTG

>82139_82139_6_SKIV2L2-SCCPDH_SKIV2L2_chr5_54711960_ENST00000545714_SCCPDH_chr1_246890194_ENST00000366510_length(amino acids)=1255AA_BP=889
MEGASRVCRQGRVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPI
KALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVF
LSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGP
SNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLP
ILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQL
LKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIE
EYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPV
LVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTL
CEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSC
FVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGRPTLSSEVGI
IICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASCIDISGEPQFLELMQLKYHEKAADKGVYIIGSSGFDSIPADLGVI
YTRNKMNGTLTAVESFLTIHSGPEGLSIHDGTWKSAIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPISYCRELKGYSIPFMGSDVS
VVRRTQRYLYENLEESPVQYAAYVTVGGITSVIKLMFAGLFFLFFVRFGIGRQLLIKFPWFFSFGYFSKQGPTQKQIDAASFTLTFFGQG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SKIV2L2-SCCPDH


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SKIV2L2-SCCPDH


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SKIV2L2-SCCPDH


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource