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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SLC11A2-PFKM (FusionGDB2 ID:82203) |
Fusion Gene Summary for SLC11A2-PFKM |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC11A2-PFKM | Fusion gene ID: 82203 | Hgene | Tgene | Gene symbol | SLC11A2 | PFKM | Gene ID | 4891 | 5213 |
| Gene name | solute carrier family 11 member 2 | phosphofructokinase, muscle | |
| Synonyms | AHMIO1|DCT1|DMT1|NRAMP2 | ATP-PFK|GSD7|PFK-1|PFK-A|PFK1|PFKA|PFKX|PPP1R122 | |
| Cytomap | 12q13.12 | 12q13.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | natural resistance-associated macrophage protein 2DMT-1NRAMP 2divalent cation transporter 1solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2solute carrier family 11 (proton-coupled divalent metal ion transporters), me | ATP-dependent 6-phosphofructokinase, muscle type6-phosphofructo-1-kinase6-phosphofructokinase type A6-phosphofructokinase, muscle typephosphofructo-1-kinase isozyme Aphosphofructokinase 1phosphofructokinase, polypeptide Xphosphofructokinase-Mphosp | |
| Modification date | 20200315 | 20200329 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000262051, ENST00000262052, ENST00000394904, ENST00000541174, ENST00000545993, ENST00000546743, ENST00000547198, ENST00000547688, ENST00000549193, | ENST00000551548, ENST00000312352, ENST00000340802, ENST00000359794, ENST00000395233, ENST00000547587, ENST00000551804, | |
| Fusion gene scores | * DoF score | 8 X 8 X 6=384 | 4 X 5 X 2=40 |
| # samples | 9 | 4 | |
| ** MAII score | log2(9/384*10)=-2.09310940439148 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/40*10)=0 | |
| Context | PubMed: SLC11A2 [Title/Abstract] AND PFKM [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SLC11A2(51386593)-PFKM(48516550), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | SLC11A2-PFKM seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. SLC11A2-PFKM seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF. SLC11A2-PFKM seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SLC11A2 | GO:0006825 | copper ion transport | 12734107 |
| Hgene | SLC11A2 | GO:0006826 | iron ion transport | 12734107|17293870 |
| Hgene | SLC11A2 | GO:0006828 | manganese ion transport | 17293870 |
| Hgene | SLC11A2 | GO:0015692 | lead ion transport | 12127992 |
| Hgene | SLC11A2 | GO:0034755 | iron ion transmembrane transport | 17293870 |
| Hgene | SLC11A2 | GO:0070574 | cadmium ion transmembrane transport | 12662899|25326704 |
| Tgene | PFKM | GO:0006002 | fructose 6-phosphate metabolic process | 6444721 |
| Fusion gene breakpoints across SLC11A2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across PFKM (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | GBM | TCGA-06-0129-01A | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| ChimerDB4 | GBM | TCGA-06-0129-01A | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
Top |
Fusion Gene ORF analysis for SLC11A2-PFKM |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000262051 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-3UTR | ENST00000262052 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-3UTR | ENST00000394904 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-3UTR | ENST00000541174 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-3UTR | ENST00000545993 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-3UTR | ENST00000546743 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-3UTR | ENST00000547198 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-3UTR | ENST00000547688 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000262051 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000262051 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-5UTR | ENST00000262051 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000262051 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000262051 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000262051 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000262052 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000262052 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-5UTR | ENST00000262052 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000262052 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000262052 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000262052 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000394904 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000394904 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-5UTR | ENST00000394904 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000394904 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000394904 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000394904 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000541174 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000541174 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-5UTR | ENST00000541174 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000541174 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000541174 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000541174 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000545993 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000545993 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-5UTR | ENST00000545993 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000545993 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000545993 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000545993 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000546743 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000546743 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-5UTR | ENST00000546743 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000546743 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000546743 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000546743 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000547198 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000547198 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-5UTR | ENST00000547198 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000547198 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000547198 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000547198 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000547688 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000547688 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-5UTR | ENST00000547688 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000547688 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000547688 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-5UTR | ENST00000547688 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| 5CDS-intron | ENST00000262051 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000262051 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000262051 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000262051 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000262051 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000262051 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000262052 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000262052 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000262052 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000262052 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000262052 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000262052 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000394904 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000394904 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000394904 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000394904 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000394904 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000394904 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000541174 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000541174 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000541174 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000541174 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000541174 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000541174 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000545993 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000545993 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000545993 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000545993 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000545993 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000545993 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000546743 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000546743 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000546743 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000546743 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000546743 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000546743 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547198 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547198 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547198 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547198 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547198 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547198 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547688 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547688 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547688 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547688 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547688 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| 5CDS-intron | ENST00000547688 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| Frame-shift | ENST00000262051 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| Frame-shift | ENST00000262052 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| Frame-shift | ENST00000394904 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| Frame-shift | ENST00000545993 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| Frame-shift | ENST00000547688 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| In-frame | ENST00000541174 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| In-frame | ENST00000546743 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| In-frame | ENST00000547198 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| intron-3CDS | ENST00000549193 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| intron-3UTR | ENST00000549193 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| intron-5UTR | ENST00000549193 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| intron-5UTR | ENST00000549193 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| intron-5UTR | ENST00000549193 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| intron-5UTR | ENST00000549193 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| intron-5UTR | ENST00000549193 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| intron-5UTR | ENST00000549193 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + |
| intron-intron | ENST00000549193 | ENST00000312352 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| intron-intron | ENST00000549193 | ENST00000359794 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| intron-intron | ENST00000549193 | ENST00000395233 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| intron-intron | ENST00000549193 | ENST00000547587 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| intron-intron | ENST00000549193 | ENST00000551548 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| intron-intron | ENST00000549193 | ENST00000551804 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48501148 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000547198 | SLC11A2 | chr12 | 51386593 | - | ENST00000340802 | PFKM | chr12 | 48516550 | + | 4006 | 1259 | 1153 | 3609 | 818 |
| ENST00000541174 | SLC11A2 | chr12 | 51386593 | - | ENST00000340802 | PFKM | chr12 | 48516550 | + | 4349 | 1602 | 1496 | 3952 | 818 |
| ENST00000546743 | SLC11A2 | chr12 | 51386593 | - | ENST00000340802 | PFKM | chr12 | 48516550 | + | 3993 | 1246 | 1140 | 3596 | 818 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000547198 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + | 0.00168665 | 0.9983133 |
| ENST00000541174 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + | 0.001532468 | 0.9984675 |
| ENST00000546743 | ENST00000340802 | SLC11A2 | chr12 | 51386593 | - | PFKM | chr12 | 48516550 | + | 0.001751434 | 0.9982486 |
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Fusion Genomic Features for SLC11A2-PFKM |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| SLC11A2 | chr12 | 51386592 | - | PFKM | chr12 | 48501147 | + | 0.00439364 | 0.99560636 |
| SLC11A2 | chr12 | 51386592 | - | PFKM | chr12 | 48516549 | + | 0.000169818 | 0.9998301 |
| SLC11A2 | chr12 | 51386592 | - | PFKM | chr12 | 48501147 | + | 0.00439364 | 0.99560636 |
| SLC11A2 | chr12 | 51386592 | - | PFKM | chr12 | 48516549 | + | 0.000169818 | 0.9998301 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SLC11A2-PFKM |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:51386593/chr12:48516550) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 118_154 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 176_179 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 1_69 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 201_208 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 230_255 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 277_301 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 323_360 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 91_96 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 118_154 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 176_179 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 1_69 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 201_208 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 230_255 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 277_301 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 323_360 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 91_96 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 118_154 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 176_179 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 1_69 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 201_208 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 230_255 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 277_301 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 323_360 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 382_408 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 91_96 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 118_154 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 176_179 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 1_69 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 201_208 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 230_255 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 277_301 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 323_360 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 91_96 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 118_154 | 395 | 558.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 176_179 | 395 | 558.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 1_69 | 395 | 558.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 201_208 | 395 | 558.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 230_255 | 395 | 558.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 277_301 | 395 | 558.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 323_360 | 395 | 558.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 91_96 | 395 | 558.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 118_154 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 176_179 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 1_69 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 201_208 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 230_255 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 277_301 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 323_360 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 91_96 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 118_154 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 176_179 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 1_69 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 201_208 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 230_255 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 277_301 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 323_360 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 382_408 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 91_96 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 155_175 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 180_200 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 209_229 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 256_276 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 302_322 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 361_381 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 70_90 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 97_117 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 155_175 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 180_200 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 209_229 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 256_276 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 302_322 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 361_381 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 70_90 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 97_117 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 155_175 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 180_200 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 209_229 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 256_276 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 302_322 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 361_381 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 409_429 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 70_90 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 97_117 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 155_175 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 180_200 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 209_229 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 256_276 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 302_322 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 361_381 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 70_90 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 97_117 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 155_175 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 180_200 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 209_229 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 256_276 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 302_322 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 361_381 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 70_90 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 97_117 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 155_175 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 180_200 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 209_229 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 256_276 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 302_322 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 361_381 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 70_90 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 97_117 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 155_175 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 180_200 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 209_229 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 256_276 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 302_322 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 361_381 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 409_429 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 70_90 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 97_117 | 428 | 591.0 | Transmembrane | Helical |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000312352 | 0 | 23 | 118_121 | 0 | 781.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000312352 | 0 | 23 | 88_89 | 0 | 781.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000340802 | 2 | 25 | 118_121 | 68 | 852.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000340802 | 2 | 25 | 88_89 | 68 | 852.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000359794 | 0 | 23 | 118_121 | 0 | 781.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000359794 | 0 | 23 | 88_89 | 0 | 781.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000395233 | 0 | 22 | 118_121 | 0 | 750.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000395233 | 0 | 22 | 88_89 | 0 | 750.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000547587 | 0 | 22 | 118_121 | 0 | 781.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000547587 | 0 | 22 | 88_89 | 0 | 781.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000551804 | 0 | 22 | 118_121 | 0 | 750.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000551804 | 0 | 22 | 88_89 | 0 | 750.0 | Nucleotide binding | ATP | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000312352 | 0 | 23 | 164_166 | 0 | 781.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000312352 | 0 | 23 | 208_210 | 0 | 781.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000312352 | 0 | 23 | 298_301 | 0 | 781.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000312352 | 0 | 23 | 2_390 | 0 | 781.0 | Region | Note=N-terminal catalytic PFK domain 1 | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000312352 | 0 | 23 | 391_401 | 0 | 781.0 | Region | Note=Interdomain linker | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000312352 | 0 | 23 | 402_780 | 0 | 781.0 | Region | Note=C-terminal regulatory PFK domain 2 | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000312352 | 0 | 23 | 528_532 | 0 | 781.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000312352 | 0 | 23 | 573_575 | 0 | 781.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000312352 | 0 | 23 | 661_664 | 0 | 781.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000340802 | 2 | 25 | 164_166 | 68 | 852.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000340802 | 2 | 25 | 208_210 | 68 | 852.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000340802 | 2 | 25 | 298_301 | 68 | 852.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000340802 | 2 | 25 | 391_401 | 68 | 852.0 | Region | Note=Interdomain linker | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000340802 | 2 | 25 | 402_780 | 68 | 852.0 | Region | Note=C-terminal regulatory PFK domain 2 | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000340802 | 2 | 25 | 528_532 | 68 | 852.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000340802 | 2 | 25 | 573_575 | 68 | 852.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000340802 | 2 | 25 | 661_664 | 68 | 852.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000359794 | 0 | 23 | 164_166 | 0 | 781.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000359794 | 0 | 23 | 208_210 | 0 | 781.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000359794 | 0 | 23 | 298_301 | 0 | 781.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000359794 | 0 | 23 | 2_390 | 0 | 781.0 | Region | Note=N-terminal catalytic PFK domain 1 | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000359794 | 0 | 23 | 391_401 | 0 | 781.0 | Region | Note=Interdomain linker | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000359794 | 0 | 23 | 402_780 | 0 | 781.0 | Region | Note=C-terminal regulatory PFK domain 2 | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000359794 | 0 | 23 | 528_532 | 0 | 781.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000359794 | 0 | 23 | 573_575 | 0 | 781.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000359794 | 0 | 23 | 661_664 | 0 | 781.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000395233 | 0 | 22 | 164_166 | 0 | 750.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000395233 | 0 | 22 | 208_210 | 0 | 750.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000395233 | 0 | 22 | 298_301 | 0 | 750.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000395233 | 0 | 22 | 2_390 | 0 | 750.0 | Region | Note=N-terminal catalytic PFK domain 1 | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000395233 | 0 | 22 | 391_401 | 0 | 750.0 | Region | Note=Interdomain linker | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000395233 | 0 | 22 | 402_780 | 0 | 750.0 | Region | Note=C-terminal regulatory PFK domain 2 | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000395233 | 0 | 22 | 528_532 | 0 | 750.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000395233 | 0 | 22 | 573_575 | 0 | 750.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000395233 | 0 | 22 | 661_664 | 0 | 750.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000547587 | 0 | 22 | 164_166 | 0 | 781.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000547587 | 0 | 22 | 208_210 | 0 | 781.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000547587 | 0 | 22 | 298_301 | 0 | 781.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000547587 | 0 | 22 | 2_390 | 0 | 781.0 | Region | Note=N-terminal catalytic PFK domain 1 | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000547587 | 0 | 22 | 391_401 | 0 | 781.0 | Region | Note=Interdomain linker | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000547587 | 0 | 22 | 402_780 | 0 | 781.0 | Region | Note=C-terminal regulatory PFK domain 2 | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000547587 | 0 | 22 | 528_532 | 0 | 781.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000547587 | 0 | 22 | 573_575 | 0 | 781.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000547587 | 0 | 22 | 661_664 | 0 | 781.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000551804 | 0 | 22 | 164_166 | 0 | 750.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000551804 | 0 | 22 | 208_210 | 0 | 750.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000551804 | 0 | 22 | 298_301 | 0 | 750.0 | Region | Substrate binding | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000551804 | 0 | 22 | 2_390 | 0 | 750.0 | Region | Note=N-terminal catalytic PFK domain 1 | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000551804 | 0 | 22 | 391_401 | 0 | 750.0 | Region | Note=Interdomain linker | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000551804 | 0 | 22 | 402_780 | 0 | 750.0 | Region | Note=C-terminal regulatory PFK domain 2 | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000551804 | 0 | 22 | 528_532 | 0 | 750.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000551804 | 0 | 22 | 573_575 | 0 | 750.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator | |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000551804 | 0 | 22 | 661_664 | 0 | 750.0 | Region | Fructose 2%2C6-bisphosphate binding%3B allosteric activator |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 382_408 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 430_440 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 462_482 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 504_506 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 528_568 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 382_408 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 430_440 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 462_482 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 504_506 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 528_568 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 430_440 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 462_482 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 504_506 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 528_568 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 382_408 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 430_440 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 462_482 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 504_506 | 399 | 562.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 528_568 | 399 | 562.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 382_408 | 395 | 558.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 430_440 | 395 | 558.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 462_482 | 395 | 558.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 504_506 | 395 | 558.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 528_568 | 395 | 558.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 382_408 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 430_440 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 462_482 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 504_506 | 399 | 569.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 528_568 | 399 | 569.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 430_440 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 462_482 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 504_506 | 428 | 591.0 | Topological domain | Extracellular |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 528_568 | 428 | 591.0 | Topological domain | Cytoplasmic |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 409_429 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 441_461 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 483_503 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262051 | - | 12 | 17 | 507_527 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 409_429 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 441_461 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 483_503 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000262052 | - | 12 | 16 | 507_527 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 441_461 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 483_503 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000394904 | - | 12 | 16 | 507_527 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 409_429 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 441_461 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 483_503 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000541174 | - | 12 | 16 | 507_527 | 399 | 562.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 409_429 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 441_461 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 483_503 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000545993 | - | 11 | 15 | 507_527 | 395 | 558.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 409_429 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 441_461 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 483_503 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547198 | - | 12 | 17 | 507_527 | 399 | 569.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 441_461 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 483_503 | 428 | 591.0 | Transmembrane | Helical |
| Hgene | SLC11A2 | chr12:51386593 | chr12:48516550 | ENST00000547688 | - | 13 | 17 | 507_527 | 428 | 591.0 | Transmembrane | Helical |
| Tgene | PFKM | chr12:51386593 | chr12:48516550 | ENST00000340802 | 2 | 25 | 2_390 | 68 | 852.0 | Region | Note=N-terminal catalytic PFK domain 1 |
Top |
Fusion Gene Sequence for SLC11A2-PFKM |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >82203_82203_1_SLC11A2-PFKM_SLC11A2_chr12_51386593_ENST00000541174_PFKM_chr12_48516550_ENST00000340802_length(transcript)=4349nt_BP=1602nt AGAGTCCAGGACTGATGGAGTCGCGCCATTCAGAGAAAGACCCAAAGATGGGGGCAGGGAGGGAACGCCGGAGGTCGCGGGGGTCTCGCC CCTTCCCCGCCGCGGCCTAGGACACATGGCCCAGCTCCCAGCTGCACCGGATGGCGCGCCCGGCCTGTGTCGGGGTGCGCTGACCTGCTT CGACGCCTCGAAAGAGGCCGACGGGCACAGGGCAAGGTCTTTCGTGGCCTCTTCGTCGGCGCCGCAGGGGGCCGGGCTGCTCTCCGGGGC CTCCCGCCGCCCCGCTTCAACAAAAGACTCATTATAACCTAACCGACTTCAGGGAGCGCCTTCTGTGTGAATAGCCTGCATACGCGGCTC AGTAATTAATCATATTCTAAGAACTCAGCCACTCAGGTATCCACCATGGTGCTGGGTCCTGAACAGAAGATGTCAGATGACAGTGTTTCT GGAGATCATGGGGAGTCTGCCAGTCTTGGTAACATCAACCCTGCCTATAGTAATCCCTCTCTTTCACAGTCCCCTGGGGACTCAGAGGAG TACTTCGCCACTTACTTTAATGAGAAGATCTCCATTCCTGAGGAGGAGTACTCTTGTTTTAGCTTTCGTAAACTCTGGGCTTTCACCGGA CCAGGTTTTCTTATGAGCATTGCCTACCTGGATCCAGGAAATATTGAATCCGATTTGCAGTCTGGAGCAGTGGCTGGATTTAAGTTGCTC TGGATCCTTCTGTTGGCCACCCTTGTGGGGCTGCTGCTCCAGCGGCTTGCAGCTAGACTGGGAGTGGTTACTGGGCTGCATCTTGCTGAA GTATGTCACCGTCAGTATCCCAAGGTCCCACGAGTCATCCTGTGGCTGATGGTGGAGTTGGCTATCATCGGCTCAGACATGCAAGAAGTC ATTGGCTCAGCCATTGCTATCAATCTTCTGTCTGTAGGAAGAATTCCTCTGTGGGGTGGCGTTCTCATCACCATTGCAGATACTTTTGTA TTTCTCTTCTTGGACAAATATGGCTTGCGGAAGCTAGAAGCATTTTTTGGCTTTCTCATCACTATTATGGCCCTCACATTTGGATATGAG TATGTTACAGTGAAACCCAGCCAGAGCCAGGTACTCAAGGGCATGTTCGTACCATCCTGTTCAGGCTGTCGCACTCCACAGATTGAACAG GCTGTGGGCATCGTGGGAGCTGTCATCATGCCACACAACATGTACCTGCATTCTGCCTTAGTCAAGTCTAGACAGGTAAACCGGAACAAT AAGCAGGAAGTTCGAGAAGCCAATAAGTACTTTTTCATTGAATCCTGCATTGCACTCTTTGTTTCCTTCATCATCAATGTCTTTGTTGTC TCAGTCTTTGCTGAAGCATTTTTTGGGAAAACCAACGAGCAGGTGGTTGAAGTCTGTACAAATACCAGCAGTCCTCATGCTGGCCTCTTT CCTAAAGATAACTCGACACTGGCTGTGGACATCTACAAAGGGGGTGTTGTGCTGGGATGTTACTTTGGGCCTGCTGCACTCTACATTTGG GCAGTGGGGATCCTGGCTGCAGGACAGAGCTCCACCATGACAGGAACCTATTCTGGCCAGTTTGTCATGGAGAGTGGATCATGACCCATG AAGAGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCCATTGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCTGCTG TCAGGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGTGTCTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGAGATC ACATCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTTCAGCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTTCGGG AACGAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAGCGTGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTCACTG GGGCTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGTGACCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAGTCCA GCTACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAATGACTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTGCATC GGATCATGGAAATTGTAGATGCCATCACTACCACTGCCCAGAGCCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGTGGAT ACCTGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGGGTTTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACACCTTT GTCGCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTCAACATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAACCAA TCACCTCAGAAGACATCAAGAATCTGGTGGTTAAGCGTCTGGGATATGACACCCGGGTTACTGTCTTGGGGCATGTGCAGAGGGGTGGGA CGCCATCAGCCTTTGACAGAATTCTGGGCAGCAGGATGGGTGTGGAAGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCAGCCT GTGTAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCCCTCATGGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATGGATG AGAAGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGCTTCATGAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGACCCC CGGTATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAACGTGGGGGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACTGTGA GGATTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCATGATGGTTTCGAGGGCCTGGCCAAGGGGCAGATAGAGGAAGCTGGCTGGA GCTATGTTGGGGGCTGGACTGGCCAAGGTGGCTCTAAACTTGGGACTAAAAGGACTCTACCCAAGAAGAGCTTTGAACAGATCAGTGCCA ATATAACTAAGTTTAACATTCAGGGCCTTGTCATCATTGGGGGCTTTGAGGCTTACACAGGGGGCCTGGAACTGATGGAGGGCAGGAAGC AGTTTGATGAGCTCTGCATCCCATTTGTGGTCATTCCTGCTACAGTCTCCAACAATGTCCCTGGCTCAGACTTCAGCGTTGGGGCTGACA CAGCACTCAATACTATCTGCACAACCTGTGACCGCATCAAGCAGTCAGCAGCTGGCACCAAGCGTCGGGTGTTTATCATTGAGACTATGG GTGGCTACTGTGGCTACCTGGCTACCATGGCTGGACTGGCAGCTGGGGCCGATGCTGCCTACATTTTTGAGGAGCCCTTCACCATTCGAG ACCTGCAGGCAAATGTTGAACATCTGGTGCAAAAGATGAAAACAACTGTGAAAAGGGGCTTGGTGTTAAGGAATGAAAAGTGCAATGAGA ACTATACCACTGACTTCATTTTCAACCTGTACTCTGAGGAGGGGAAGGGCATCTTCGACAGCAGGAAGAATGTGCTTGGTCACATGCAGC AGGGTGGGAGCCCAACCCCATTTGATAGGAATTTTGCCACTAAGATGGGCGCCAAGGCTATGAACTGGATGTCTGGGAAAATCAAAGAGA GTTACCGTAATGGGCGGATCTTTGCCAATACTCCAGATTCGGGCTGTGTTCTGGGGATGCGTAAGAGGGCTCTGGTCTTCCAACCAGTGG CTGAGCTGAAGGACCAGACAGATTTTGAGCATCGAATCCCCAAGGAACAGTGGTGGCTGAAACTGAGGCCCATCCTCAAAATCCTAGCCA AGTACGAGATTGACTTGGACACTTCAGACCATGCCCACCTGGAGCACATCACCCGGAAGCGGTCCGGGGAAGCTGCCGTCTAAACCTCTC TGGAGTGAGGGGAATAGATTACCTGATCATGGTCAGCTCACACCCTAATAAGTCCACATCTTCTCAGTGTTTTAGCTGTTTTTTTCATTA GGTTTCCTTTTATTCTGTACCTTGCAGCCATGACCAGTTCTGGCCAGGAGCTGGAGGAGCAGGCAGTGGGTGGGAGCTCCTTTTAGGTAG AATTTAACATGACTTCTGCCCCAGCTTTATCTGTCACACAAGGCTGGGCACCTCTAGTGCTACTGCTAGATATCACTTACTCAGTTAGAA TTTTCCTAAAAATAAGCTTTATTTATTTCTTTGTGATAACAAAGAGTCTTGGTTCCTCTACTACTTTTACTACAGTGACAAATTGTAACT >82203_82203_1_SLC11A2-PFKM_SLC11A2_chr12_51386593_ENST00000541174_PFKM_chr12_48516550_ENST00000340802_length(amino acids)=818AA_BP=35 MLLWACCTLHLGSGDPGCRTELHHDRNLFWPVCHGEWIMTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVH EGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKA GKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPE CPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVM ALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPA AGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANITKFNIQGLVIIGGFEAY TGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADA AYIFEEPFTIRDLQANVEHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAK AMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVFQPVAELKDQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHITR -------------------------------------------------------------- >82203_82203_2_SLC11A2-PFKM_SLC11A2_chr12_51386593_ENST00000546743_PFKM_chr12_48516550_ENST00000340802_length(transcript)=3993nt_BP=1246nt GGGGAGGGCGTTAGCCAGCGTGGCGCTGGCTCCCGGAATATGGAGCCCTGGGCGCGGGGGCGGCGTGTCAGGTGGTTGCGGAGCTGGTAA GAATCATATTCTAAGAACTCAGCCACTCAGGTATCCACCATGGTGCTGGGTCCTGAACAGAAGATGTCAGATGTCCCCTGGGGACTCAGA GGAGTACTTCGCCACTTACTTTAATGAGAAGATCTCCATTCCTGAGGAGGAGTACTCTTGTTTTAGCTTTCGTAAACTCTGGGCTTTCAC CGGACCAGGTTTTCTTATGAGCATTGCCTACCTGGATCCAGGAAATATTGAATCCGATTTGCAGTCTGGAGCAGTGGCTGGATTTAAGTT GCTCTGGATCCTTCTGTTGGCCACCCTTGTGGGGCTGCTGCTCCAGCGGCTTGCAGCTAGACTGGGAGTGGTTACTGGGCTGCATCTTGC TGAAGTATGTCACCGTCAGTATCCCAAGGTCCCACGAGTCATCCTGTGGCTGATGGTGGAGTTGGCTATCATCGGCTCAGACATGCAAGA AGTCATTGGCTCAGCCATTGCTATCAATCTTCTGTCTGTAGGAAGAATTCCTCTGTGGGGTGGCGTTCTCATCACCATTGCAGATACTTT TGTATTTCTCTTCTTGGACAAATATGGCTTGCGGAAGCTAGAAGCATTTTTTGGCTTTCTCATCACTATTATGGCCCTCACATTTGGATA TGAGTATGTTACAGTGAAACCCAGCCAGAGCCAGGTACTCAAGGGCATGTTCGTACCATCCTGTTCAGGCTGTCGCACTCCACAGATTGA ACAGGCTGTGGGCATCGTGGGAGCTGTCATCATGCCACACAACATGTACCTGCATTCTGCCTTAGTCAAGTCTAGACAGGTAAACCGGAA CAATAAGCAGGAAGTTCGAGAAGCCAATAAGTACTTTTTCATTGAATCCTGCATTGCACTCTTTGTTTCCTTCATCATCAATGTCTTTGT TGTCTCAGTCTTTGCTGAAGCATTTTTTGGGAAAACCAACGAGCAGGTGGTTGAAGTCTGTACAAATACCAGCAGTCCTCATGCTGGCCT CTTTCCTAAAGATAACTCGACACTGGCTGTGGACATCTACAAAGGGGGTGTTGTGCTGGGATGTTACTTTGGGCCTGCTGCACTCTACAT TTGGGCAGTGGGGATCCTGGCTGCAGGACAGAGCTCCACCATGACAGGAACCTATTCTGGCCAGTTTGTCATGGAGAGTGGATCATGACC CATGAAGAGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCCATTGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCT GCTGTCAGGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGTGTCTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGA GATCACATCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTTCAGCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTT CGGGAACGAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAGCGTGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTC ACTGGGGCTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGTGACCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAG TCCAGCTACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAATGACTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTG CATCGGATCATGGAAATTGTAGATGCCATCACTACCACTGCCCAGAGCCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGT GGATACCTGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGGGTTTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACAC CTTTGTCGCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTCAACATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAA CCAATCACCTCAGAAGACATCAAGAATCTGGTGGTTAAGCGTCTGGGATATGACACCCGGGTTACTGTCTTGGGGCATGTGCAGAGGGGT GGGACGCCATCAGCCTTTGACAGAATTCTGGGCAGCAGGATGGGTGTGGAAGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCA GCCTGTGTAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCCCTCATGGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATG GATGAGAAGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGCTTCATGAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGA CCCCCGGTATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAACGTGGGGGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACT GTGAGGATTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCATGATGGTTTCGAGGGCCTGGCCAAGGGGCAGATAGAGGAAGCTGGC TGGAGCTATGTTGGGGGCTGGACTGGCCAAGGTGGCTCTAAACTTGGGACTAAAAGGACTCTACCCAAGAAGAGCTTTGAACAGATCAGT GCCAATATAACTAAGTTTAACATTCAGGGCCTTGTCATCATTGGGGGCTTTGAGGCTTACACAGGGGGCCTGGAACTGATGGAGGGCAGG AAGCAGTTTGATGAGCTCTGCATCCCATTTGTGGTCATTCCTGCTACAGTCTCCAACAATGTCCCTGGCTCAGACTTCAGCGTTGGGGCT GACACAGCACTCAATACTATCTGCACAACCTGTGACCGCATCAAGCAGTCAGCAGCTGGCACCAAGCGTCGGGTGTTTATCATTGAGACT ATGGGTGGCTACTGTGGCTACCTGGCTACCATGGCTGGACTGGCAGCTGGGGCCGATGCTGCCTACATTTTTGAGGAGCCCTTCACCATT CGAGACCTGCAGGCAAATGTTGAACATCTGGTGCAAAAGATGAAAACAACTGTGAAAAGGGGCTTGGTGTTAAGGAATGAAAAGTGCAAT GAGAACTATACCACTGACTTCATTTTCAACCTGTACTCTGAGGAGGGGAAGGGCATCTTCGACAGCAGGAAGAATGTGCTTGGTCACATG CAGCAGGGTGGGAGCCCAACCCCATTTGATAGGAATTTTGCCACTAAGATGGGCGCCAAGGCTATGAACTGGATGTCTGGGAAAATCAAA GAGAGTTACCGTAATGGGCGGATCTTTGCCAATACTCCAGATTCGGGCTGTGTTCTGGGGATGCGTAAGAGGGCTCTGGTCTTCCAACCA GTGGCTGAGCTGAAGGACCAGACAGATTTTGAGCATCGAATCCCCAAGGAACAGTGGTGGCTGAAACTGAGGCCCATCCTCAAAATCCTA GCCAAGTACGAGATTGACTTGGACACTTCAGACCATGCCCACCTGGAGCACATCACCCGGAAGCGGTCCGGGGAAGCTGCCGTCTAAACC TCTCTGGAGTGAGGGGAATAGATTACCTGATCATGGTCAGCTCACACCCTAATAAGTCCACATCTTCTCAGTGTTTTAGCTGTTTTTTTC ATTAGGTTTCCTTTTATTCTGTACCTTGCAGCCATGACCAGTTCTGGCCAGGAGCTGGAGGAGCAGGCAGTGGGTGGGAGCTCCTTTTAG GTAGAATTTAACATGACTTCTGCCCCAGCTTTATCTGTCACACAAGGCTGGGCACCTCTAGTGCTACTGCTAGATATCACTTACTCAGTT AGAATTTTCCTAAAAATAAGCTTTATTTATTTCTTTGTGATAACAAAGAGTCTTGGTTCCTCTACTACTTTTACTACAGTGACAAATTGT >82203_82203_2_SLC11A2-PFKM_SLC11A2_chr12_51386593_ENST00000546743_PFKM_chr12_48516550_ENST00000340802_length(amino acids)=818AA_BP=35 MLLWACCTLHLGSGDPGCRTELHHDRNLFWPVCHGEWIMTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVH EGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKA GKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPE CPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVM ALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPA AGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANITKFNIQGLVIIGGFEAY TGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADA AYIFEEPFTIRDLQANVEHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAK AMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVFQPVAELKDQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHITR -------------------------------------------------------------- >82203_82203_3_SLC11A2-PFKM_SLC11A2_chr12_51386593_ENST00000547198_PFKM_chr12_48516550_ENST00000340802_length(transcript)=4006nt_BP=1259nt GCGTGTCAGGTGGTTGCGGAGCTGAATCATATTCTAAGAACTCAGCCACTCAGGTATCCACCATGGTGCTGGGTCCTGAACAGAAGATGT CAGATGACAGTGTTTCTGGAGATCATGGGGAGTCTGCCAGTCTTGGTAACATCAACCCTGCCTATAGTAATCCCTCTCTTTCACAGTCCC CTGGGGACTCAGAGGAGTACTTCGCCACTTACTTTAATGAGAAGATCTCCATTCCTGAGGAGGAGTACTCTTGTTTTAGCTTTCGTAAAC TCTGGGCTTTCACCGGACCAGGTTTTCTTATGAGCATTGCCTACCTGGATCCAGGAAATATTGAATCCGATTTGCAGTCTGGAGCAGTGG CTGGATTTAAGTTGCTCTGGATCCTTCTGTTGGCCACCCTTGTGGGGCTGCTGCTCCAGCGGCTTGCAGCTAGACTGGGAGTGGTTACTG GGCTGCATCTTGCTGAAGTATGTCACCGTCAGTATCCCAAGGTCCCACGAGTCATCCTGTGGCTGATGGTGGAGTTGGCTATCATCGGCT CAGACATGCAAGAAGTCATTGGCTCAGCCATTGCTATCAATCTTCTGTCTGTAGGAAGAATTCCTCTGTGGGGTGGCGTTCTCATCACCA TTGCAGATACTTTTGTATTTCTCTTCTTGGACAAATATGGCTTGCGGAAGCTAGAAGCATTTTTTGGCTTTCTCATCACTATTATGGCCC TCACATTTGGATATGAGTATGTTACAGTGAAACCCAGCCAGAGCCAGGTACTCAAGGGCATGTTCGTACCATCCTGTTCAGGCTGTCGCA CTCCACAGATTGAACAGGCTGTGGGCATCGTGGGAGCTGTCATCATGCCACACAACATGTACCTGCATTCTGCCTTAGTCAAGTCTAGAC AGGTAAACCGGAACAATAAGCAGGAAGTTCGAGAAGCCAATAAGTACTTTTTCATTGAATCCTGCATTGCACTCTTTGTTTCCTTCATCA TCAATGTCTTTGTTGTCTCAGTCTTTGCTGAAGCATTTTTTGGGAAAACCAACGAGCAGGTGGTTGAAGTCTGTACAAATACCAGCAGTC CTCATGCTGGCCTCTTTCCTAAAGATAACTCGACACTGGCTGTGGACATCTACAAAGGGGGTGTTGTGCTGGGATGTTACTTTGGGCCTG CTGCACTCTACATTTGGGCAGTGGGGATCCTGGCTGCAGGACAGAGCTCCACCATGACAGGAACCTATTCTGGCCAGTTTGTCATGGAGA GTGGATCATGACCCATGAAGAGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCCATTGCTGTCTTAACCTCTGGTGGAGATGCCCA AGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGTGTCTTCTTTGTCCATGAGGGTTATCAAGGCCT GGTGGATGGTGGAGATCACATCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTTCAGCTGGGAGGCACGGTGATTGGAAGTGCCCG GTGCAAGGACTTTCGGGAACGAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAGCGTGGGATCACCAATCTCTGTGTCATTGGGGG TGATGGCAGCCTCACTGGGGCTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGTGACCTCCAGAAAGCAGGTAAGATCACAGATGA GGAGGCTACGAAGTCCAGCTACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAATGACTTCTGTGGCACCGATATGACCATTGGCAC TGACTCTGCCCTGCATCGGATCATGGAAATTGTAGATGCCATCACTACCACTGCCCAGAGCCACCAGAGGACATTTGTGTTAGAAGTAAT GGGCCGCCACTGTGGATACCTGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGGGTTTTTATTCCTGAATGTCCACCAGATGACGA CTGGGAGGAACACCTTTGTCGCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTCAACATCATCATTGTGGCTGAGGGTGCAATTGA CAAGAATGGAAAACCAATCACCTCAGAAGACATCAAGAATCTGGTGGTTAAGCGTCTGGGATATGACACCCGGGTTACTGTCTTGGGGCA TGTGCAGAGGGGTGGGACGCCATCAGCCTTTGACAGAATTCTGGGCAGCAGGATGGGTGTGGAAGCAGTGATGGCACTTTTGGAGGGGAC CCCAGATACCCCAGCCTGTGTAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCCCTCATGGAATGTGTCCAGGTGACCAAAGATGT GACCAAGGCCATGGATGAGAAGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGCTTCATGAACAACTGGGAGGTGTACAAGCTTCT AGCTCATGTCAGACCCCCGGTATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAACGTGGGGGCTCCGGCTGCAGGCATGAATGCTGC TGTTCGCTCCACTGTGAGGATTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCATGATGGTTTCGAGGGCCTGGCCAAGGGGCAGAT AGAGGAAGCTGGCTGGAGCTATGTTGGGGGCTGGACTGGCCAAGGTGGCTCTAAACTTGGGACTAAAAGGACTCTACCCAAGAAGAGCTT TGAACAGATCAGTGCCAATATAACTAAGTTTAACATTCAGGGCCTTGTCATCATTGGGGGCTTTGAGGCTTACACAGGGGGCCTGGAACT GATGGAGGGCAGGAAGCAGTTTGATGAGCTCTGCATCCCATTTGTGGTCATTCCTGCTACAGTCTCCAACAATGTCCCTGGCTCAGACTT CAGCGTTGGGGCTGACACAGCACTCAATACTATCTGCACAACCTGTGACCGCATCAAGCAGTCAGCAGCTGGCACCAAGCGTCGGGTGTT TATCATTGAGACTATGGGTGGCTACTGTGGCTACCTGGCTACCATGGCTGGACTGGCAGCTGGGGCCGATGCTGCCTACATTTTTGAGGA GCCCTTCACCATTCGAGACCTGCAGGCAAATGTTGAACATCTGGTGCAAAAGATGAAAACAACTGTGAAAAGGGGCTTGGTGTTAAGGAA TGAAAAGTGCAATGAGAACTATACCACTGACTTCATTTTCAACCTGTACTCTGAGGAGGGGAAGGGCATCTTCGACAGCAGGAAGAATGT GCTTGGTCACATGCAGCAGGGTGGGAGCCCAACCCCATTTGATAGGAATTTTGCCACTAAGATGGGCGCCAAGGCTATGAACTGGATGTC TGGGAAAATCAAAGAGAGTTACCGTAATGGGCGGATCTTTGCCAATACTCCAGATTCGGGCTGTGTTCTGGGGATGCGTAAGAGGGCTCT GGTCTTCCAACCAGTGGCTGAGCTGAAGGACCAGACAGATTTTGAGCATCGAATCCCCAAGGAACAGTGGTGGCTGAAACTGAGGCCCAT CCTCAAAATCCTAGCCAAGTACGAGATTGACTTGGACACTTCAGACCATGCCCACCTGGAGCACATCACCCGGAAGCGGTCCGGGGAAGC TGCCGTCTAAACCTCTCTGGAGTGAGGGGAATAGATTACCTGATCATGGTCAGCTCACACCCTAATAAGTCCACATCTTCTCAGTGTTTT AGCTGTTTTTTTCATTAGGTTTCCTTTTATTCTGTACCTTGCAGCCATGACCAGTTCTGGCCAGGAGCTGGAGGAGCAGGCAGTGGGTGG GAGCTCCTTTTAGGTAGAATTTAACATGACTTCTGCCCCAGCTTTATCTGTCACACAAGGCTGGGCACCTCTAGTGCTACTGCTAGATAT CACTTACTCAGTTAGAATTTTCCTAAAAATAAGCTTTATTTATTTCTTTGTGATAACAAAGAGTCTTGGTTCCTCTACTACTTTTACTAC >82203_82203_3_SLC11A2-PFKM_SLC11A2_chr12_51386593_ENST00000547198_PFKM_chr12_48516550_ENST00000340802_length(amino acids)=818AA_BP=35 MLLWACCTLHLGSGDPGCRTELHHDRNLFWPVCHGEWIMTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVH EGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKA GKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPE CPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVM ALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPA AGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANITKFNIQGLVIIGGFEAY TGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADA AYIFEEPFTIRDLQANVEHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAK AMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVFQPVAELKDQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHITR -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SLC11A2-PFKM |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SLC11A2-PFKM |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SLC11A2-PFKM |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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