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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SLC11A2-SQSTM1 (FusionGDB2 ID:82206)

Fusion Gene Summary for SLC11A2-SQSTM1

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC11A2-SQSTM1
Fusion gene ID: 82206
HgeneTgene
Gene symbol

SLC11A2

SQSTM1

Gene ID

4891

8878

Gene namesolute carrier family 11 member 2sequestosome 1
SynonymsAHMIO1|DCT1|DMT1|NRAMP2A170|DMRV|FTDALS3|NADGP|OSIL|PDB3|ZIP3|p60|p62|p62B
Cytomap

12q13.12

5q35.3

Type of geneprotein-codingprotein-coding
Descriptionnatural resistance-associated macrophage protein 2DMT-1NRAMP 2divalent cation transporter 1solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2solute carrier family 11 (proton-coupled divalent metal ion transporters), mesequestosome-1EBI3-associated protein of 60 kDaEBI3-associated protein p60EBIAPautophagy receptor p62oxidative stress induced likephosphotyrosine independent ligand for the Lck SH2 domain p62phosphotyrosine-independent ligand for the Lck SH2 domain
Modification date2020031520200327
UniProtAcc.

Q13501

Ensembl transtripts involved in fusion geneENST00000262051, ENST00000262052, 
ENST00000394904, ENST00000541174, 
ENST00000545993, ENST00000547198, 
ENST00000547688, ENST00000546743, 
ENST00000549193, 		ENST00000360718, 
ENST00000389805, ENST00000402874, 
ENST00000506690, ENST00000510187, 
ENST00000376929, 
Fusion gene scores* DoF score8 X 8 X 6=38433 X 21 X 17=11781
# samples 938
** MAII scorelog2(9/384*10)=-2.09310940439148
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(38/11781*10)=-4.95431877505661
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC11A2 [Title/Abstract] AND SQSTM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSLC11A2(51402258)-SQSTM1(179260586), # samples:1
Anticipated loss of major functional domain due to fusion event.SLC11A2-SQSTM1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSLC11A2

GO:0006825

copper ion transport

12734107

HgeneSLC11A2

GO:0006826

iron ion transport

12734107|17293870

HgeneSLC11A2

GO:0006828

manganese ion transport

17293870

HgeneSLC11A2

GO:0015692

lead ion transport

12127992

HgeneSLC11A2

GO:0034755

iron ion transmembrane transport

17293870

HgeneSLC11A2

GO:0070574

cadmium ion transmembrane transport

12662899|25326704

TgeneSQSTM1

GO:0006914

autophagy

20452972

TgeneSQSTM1

GO:0007032

endosome organization

27368102

TgeneSQSTM1

GO:0031397

negative regulation of protein ubiquitination

20452972

TgeneSQSTM1

GO:0061635

regulation of protein complex stability

25127057

TgeneSQSTM1

GO:1905719

protein localization to perinuclear region of cytoplasm

27368102


check buttonFusion gene breakpoints across SLC11A2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SQSTM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-D7-6520SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+


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Fusion Gene ORF analysis for SLC11A2-SQSTM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000262051ENST00000360718SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000262051ENST00000389805SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000262051ENST00000402874SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000262051ENST00000506690SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000262051ENST00000510187SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000262052ENST00000360718SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000262052ENST00000389805SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000262052ENST00000402874SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000262052ENST00000506690SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000262052ENST00000510187SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000394904ENST00000360718SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000394904ENST00000389805SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000394904ENST00000402874SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000394904ENST00000506690SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000394904ENST00000510187SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000541174ENST00000360718SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000541174ENST00000389805SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000541174ENST00000402874SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000541174ENST00000506690SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000541174ENST00000510187SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000545993ENST00000360718SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000545993ENST00000389805SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000545993ENST00000402874SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000545993ENST00000506690SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000545993ENST00000510187SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000547198ENST00000360718SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000547198ENST00000389805SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000547198ENST00000402874SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000547198ENST00000506690SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000547198ENST00000510187SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000547688ENST00000360718SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000547688ENST00000389805SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000547688ENST00000402874SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000547688ENST00000506690SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5CDS-intronENST00000547688ENST00000510187SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-3CDSENST00000546743ENST00000376929SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-3CDSENST00000549193ENST00000376929SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-intronENST00000546743ENST00000360718SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-intronENST00000546743ENST00000389805SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-intronENST00000546743ENST00000402874SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-intronENST00000546743ENST00000506690SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-intronENST00000546743ENST00000510187SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-intronENST00000549193ENST00000360718SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-intronENST00000549193ENST00000389805SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-intronENST00000549193ENST00000402874SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-intronENST00000549193ENST00000506690SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
5UTR-intronENST00000549193ENST00000510187SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
Frame-shiftENST00000541174ENST00000376929SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
Frame-shiftENST00000547198ENST00000376929SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
In-frameENST00000262051ENST00000376929SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
In-frameENST00000262052ENST00000376929SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
In-frameENST00000394904ENST00000376929SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
In-frameENST00000545993ENST00000376929SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+
In-frameENST00000547688ENST00000376929SLC11A2chr12

51402258

-SQSTM1chr5

179260586

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000262051SLC11A2chr1251402258-ENST00000376929SQSTM1chr5179260586+210727119701422182
ENST00000262052SLC11A2chr1251402258-ENST00000376929SQSTM1chr5179260586+213229619951447182
ENST00000394904SLC11A2chr1251402258-ENST00000376929SQSTM1chr5179260586+215632050673207
ENST00000547688SLC11A2chr1251402258-ENST00000376929SQSTM1chr5179260586+2348512242865207
ENST00000545993SLC11A2chr1251402258-ENST00000376929SQSTM1chr5179260586+211828257635192

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000262051ENST00000376929SLC11A2chr1251402258-SQSTM1chr5179260586+0.0027973120.99720275
ENST00000262052ENST00000376929SLC11A2chr1251402258-SQSTM1chr5179260586+0.0027512830.9972487
ENST00000394904ENST00000376929SLC11A2chr1251402258-SQSTM1chr5179260586+0.0073063780.99269366
ENST00000547688ENST00000376929SLC11A2chr1251402258-SQSTM1chr5179260586+0.0071949940.99280506
ENST00000545993ENST00000376929SLC11A2chr1251402258-SQSTM1chr5179260586+0.003937020.99606293

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Fusion Genomic Features for SLC11A2-SQSTM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SLC11A2chr1251402258-SQSTM1chr5179260586+0.0006005980.9993994
SLC11A2chr1251402258-SQSTM1chr5179260586+0.0006005980.9993994

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for SLC11A2-SQSTM1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:51402258/chr5:179260586)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.SQSTM1

Q13501

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Autophagy receptor required for selective macroautophagy (aggrephagy). Functions as a bridge between polyubiquitinated cargo and autophagosomes. Interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family (PubMed:16286508, PubMed:20168092, PubMed:24128730, PubMed:28404643, PubMed:22622177). Along with WDFY3, involved in the formation and autophagic degradation of cytoplasmic ubiquitin-containing inclusions (p62 bodies, ALIS/aggresome-like induced structures). Along with WDFY3, required to recruit ubiquitinated proteins to PML bodies in the nucleus (PubMed:24128730, PubMed:20168092). May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Involved in endosome organization by retaining vesicles in the perinuclear cloud: following ubiquitination by RNF26, attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport (PubMed:27368102). Promotes relocalization of 'Lys-63'-linked ubiquitinated STING1 to autophagosomes (PubMed:29496741). Acts as an activator of the NFE2L2/NRF2 pathway via interaction with KEAP1: interaction inactivates the BCR(KEAP1) complex, promoting nuclear accumulation of NFE2L2/NRF2 and subsequent expression of cytoprotective genes (PubMed:20452972, PubMed:28380357, PubMed:33393215). {ECO:0000250|UniProtKB:O08623, ECO:0000250|UniProtKB:Q64337, ECO:0000269|PubMed:10356400, ECO:0000269|PubMed:10747026, ECO:0000269|PubMed:11244088, ECO:0000269|PubMed:12471037, ECO:0000269|PubMed:15340068, ECO:0000269|PubMed:15802564, ECO:0000269|PubMed:15911346, ECO:0000269|PubMed:15953362, ECO:0000269|PubMed:16079148, ECO:0000269|PubMed:16286508, ECO:0000269|PubMed:19931284, ECO:0000269|PubMed:20168092, ECO:0000269|PubMed:20452972, ECO:0000269|PubMed:22622177, ECO:0000269|PubMed:24128730, ECO:0000269|PubMed:27368102, ECO:0000269|PubMed:28380357, ECO:0000269|PubMed:28404643, ECO:0000269|PubMed:29496741, ECO:0000269|PubMed:33393215}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-3161_6990591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-4171_6990591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-31670_9090591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-41770_9090591.0TransmembraneHelical
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000036071847272_294239357.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000037692969272_294239357.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000040287458272_294239357.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000036071847389_434239357.0DomainUBA
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000037692969389_434239357.0DomainUBA
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000038980558389_434323441.0DomainUBA
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000040287458389_434239357.0DomainUBA
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000036071847336_341239357.0MotifNote=LIR
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000037692969336_341239357.0MotifNote=LIR
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000038980558336_341323441.0MotifNote=LIR
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000040287458336_341239357.0MotifNote=LIR
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000036071847321_342239357.0RegionMAP1LC3B-binding
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000037692969321_342239357.0RegionMAP1LC3B-binding
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000038980558321_342323441.0RegionMAP1LC3B-binding
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000040287458321_342239357.0RegionMAP1LC3B-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317118_15461569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317176_17961569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-3171_6961569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317201_20861569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317230_25561569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317277_30161569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317323_36061569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317382_40861569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317430_44061569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317462_48261569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317504_50661569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317528_56861569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-31791_9661569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316118_15461562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316176_17961562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-3161_6961562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316201_20861562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316230_25561562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316277_30161562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316323_36061562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316382_40861562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316430_44061562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316462_48261562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316504_50661562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316528_56861562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-31691_9661562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316118_15490591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316176_17990591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316201_20890591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316230_25590591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316277_30190591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316323_36090591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316382_40890591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316430_44090591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316462_48290591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316504_50690591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316528_56890591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-31691_9690591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316118_15461562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316176_17961562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-3161_6961562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316201_20861562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316230_25561562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316277_30161562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316323_36061562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316382_40861562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316430_44061562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316462_48261562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316504_50661562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316528_56861562.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-31691_9661562.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215118_15457558.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215176_17957558.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-2151_6957558.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215201_20857558.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215230_25557558.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215277_30157558.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215323_36057558.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215382_40857558.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215430_44057558.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215462_48257558.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215504_50657558.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215528_56857558.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-21591_9657558.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317118_15461569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317176_17961569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-3171_6961569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317201_20861569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317230_25561569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317277_30161569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317323_36061569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317382_40861569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317430_44061569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317462_48261569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317504_50661569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317528_56861569.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-31791_9661569.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417118_15490591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417176_17990591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417201_20890591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417230_25590591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417277_30190591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417323_36090591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417382_40890591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417430_44090591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417462_48290591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417504_50690591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417528_56890591.0Topological domainCytoplasmic
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-41791_9690591.0Topological domainExtracellular
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317155_17561569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317180_20061569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317209_22961569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317256_27661569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317302_32261569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317361_38161569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317409_42961569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317441_46161569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317483_50361569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-317507_52761569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-31770_9061569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262051-31797_11761569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316155_17561562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316180_20061562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316209_22961562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316256_27661562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316302_32261562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316361_38161562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316409_42961562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316441_46161562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316483_50361562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-316507_52761562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-31670_9061562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000262052-31697_11761562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316155_17590591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316180_20090591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316209_22990591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316256_27690591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316302_32290591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316361_38190591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316409_42990591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316441_46190591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316483_50390591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-316507_52790591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000394904-31697_11790591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316155_17561562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316180_20061562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316209_22961562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316256_27661562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316302_32261562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316361_38161562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316409_42961562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316441_46161562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316483_50361562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-316507_52761562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-31670_9061562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000541174-31697_11761562.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215155_17557558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215180_20057558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215209_22957558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215256_27657558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215302_32257558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215361_38157558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215409_42957558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215441_46157558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215483_50357558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-215507_52757558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-21570_9057558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000545993-21597_11757558.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317155_17561569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317180_20061569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317209_22961569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317256_27661569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317302_32261569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317361_38161569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317409_42961569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317441_46161569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317483_50361569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-317507_52761569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-31770_9061569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547198-31797_11761569.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417155_17590591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417180_20090591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417209_22990591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417256_27690591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417302_32290591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417361_38190591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417409_42990591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417441_46190591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417483_50390591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-417507_52790591.0TransmembraneHelical
HgeneSLC11A2chr12:51402258chr5:179260586ENST00000547688-41797_11790591.0TransmembraneHelical
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000038980558272_294323441.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr12:51402258chr5:179260586ENST00000360718473_102239357.0DomainPB1
TgeneSQSTM1chr12:51402258chr5:179260586ENST00000376929693_102239357.0DomainPB1
TgeneSQSTM1chr12:51402258chr5:179260586ENST00000389805583_102323441.0DomainPB1
TgeneSQSTM1chr12:51402258chr5:179260586ENST00000402874583_102239357.0DomainPB1
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000036071847228_233239357.0MotifNote=TRAF6-binding
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000037692969228_233239357.0MotifNote=TRAF6-binding
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000038980558228_233323441.0MotifNote=TRAF6-binding
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000040287458228_233239357.0MotifNote=TRAF6-binding
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000036071847170_220239357.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000037692969170_220239357.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000038980558170_220323441.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000040287458170_220239357.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000036071847122_167239357.0Zinc fingerZZ-type
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000037692969122_167239357.0Zinc fingerZZ-type
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000038980558122_167323441.0Zinc fingerZZ-type
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000040287458122_167239357.0Zinc fingerZZ-type


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Fusion Gene Sequence for SLC11A2-SQSTM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>82206_82206_1_SLC11A2-SQSTM1_SLC11A2_chr12_51402258_ENST00000262051_SQSTM1_chr5_179260586_ENST00000376929_length(transcript)=2107nt_BP=271nt
GGAGCCCTGGGCGCGGGGGCGGCGTGTCAGGTGGTTGCGGAGCTGGTAAGAATCATATTCTAAGAACTCAGCCACTCAGGTATCCACCAT
GGTGCTGGGTCCTGAACAGAAGATGTCAGATGACAGTGTTTCTGGAGATCATGGGGAGTCTGCCAGTCTTGGTAACATCAACCCTGCCTA
TAGTAATCCCTCTCTTTCACAGTCCCCTGGGGACTCAGAGGAGTACTTCGCCACTTACTTTAATGAGAAGATCTCCATTCCTGAGGAGGA
GGAACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATGACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACT
CCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTA
CCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGTCCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCT
CACCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGGCTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGACCACT
TTTGCCCACCTCTTCTGCGTGCCCCTCTTCTGTCTCATAGTTGTGTTAAGCTTGCGTAGAATTGCAGGTCTCTGTACGGGCCAGTTTCTC
TGCCTTCTTCCAGGATCAGGGGTTAGGGTGCAAGAAGCCATTTAGGGCAGCAAAACAAGTGACATGAAGGGAGGGTCCCTGTGTGTGTGT
GTGCTGATGTTTCCTGGGTGCCCTGGCTCCTTGCAGCAGGGCTGGGCCTGCGAGACCCAAGGCTCACTGCAGCGCGCTCCTGACCCCTCC
CTGCAGGGGCTACGTTAGCAGCCCAGCACATAGCTTGCCTAATGGCTTTCACTTTCTCTTTTGTTTTAAATGACTCATAGGTCCCTGACA
TTTAGTTGATTATTTTCTGCTACAGACCTGGTACACTCTGATTTTAGATAAAGTAAGCCTAGGTGTTGTCAGCAGGCAGGCTGGGGAGGC
CAGTGTTGTGGGCTTCCTGCTGGGACTGAGAAGGCTCACGAAGGGCATCCGCAATGTTGGTTTCACTGAGAGCTGCCTCCTGGTCTCTTC
ACCACTGTAGTTCTCTCATTTCCAAACCATCAGCTGCTTTTAAAATAAGATCTCTTTGTAGCCATCCTGTTAAATTTGTAAACAATCTAA
TTAAATGGCATCAGCACTTTAACCAATGACGTTTGCATAGAGAGAAATGATTGACAGTAAGTTTATTGTTAATGGTTCTTACAGAGTATC
TTTAAAAGTGCCTTAGGGGAACCCTGTCCCTCCTAACAAGTGTATCTCGATTAATAACCTGCCAGTCCCAGATCACACATCATCATCGAA
GTCTTCCCCAGTTATAAAGAGGTCACATAGTCGTGTGGGTCGAGGATTCTGTGCCTCCAGGACCAGGGGCCCACCCTCTGCCCAGGGAGT
CCTTGCGTCCCATGAGGTCTTCCCGCAAGGCCTCTCAGACCCAGATGTGACGGGGTGTGTGGCCCGAGGAAGCTGGACAGCGGCAGTGGG
CCTGCTGAGGCCTTCTCTTGAGGCCTGTGCTCTGGGGGTCCCTTGCTTAGCCTGTGCTGGACCAGCTGGCCTGGGGTCCCTCTGAAGAGA
CCTTGGCTGCTCACTGTCCACATGTGAACTTTTTCTAGGTGGCAGGACAAATTGCGCCCATTTAGAGGATGTGGCTGTAACCTGCTGGAT
GGGACTCCATAGCTCCTTCCCAGGACCCCTCAGCTCCCCGGCACTGCAGTCTGCAGAGTTCTCCTGGAGGCAGGGGCTGCTGCCTTGTTT
CACCTTCCATGTCAGGCCAGCCTGTCCCTGAAAGAGAAGATGGCCATGCCCTCCATGTGTAAGAACAATGCCAGGGCCCAGGAGGACCGC
CTGCCCTGCCTGGGCCTTGGCTGGGCCTCTGGTTCTGACACTTTCTGCTGGAAGCTGTCAGGCTGGGACAGGCTTTGATTTTGAGGGTTA

>82206_82206_1_SLC11A2-SQSTM1_SLC11A2_chr12_51402258_ENST00000262051_SQSTM1_chr5_179260586_ENST00000376929_length(amino acids)=182AA_BP=
MGPGIVLTHGGHGHLLFQGQAGLTWKVKQGSSPCLQENSADCSAGELRGPGKELWSPIQQVTATSSKWAQFVLPPRKSSHVDSEQPRSLQ
RDPRPAGPAQAKQGTPRAQASREGLSRPTAAVQLPRATHPVTSGSERPCGKTSWDARTPWAEGGPLVLEAQNPRPTRLCDLFITGEDFDD

--------------------------------------------------------------
>82206_82206_2_SLC11A2-SQSTM1_SLC11A2_chr12_51402258_ENST00000262052_SQSTM1_chr5_179260586_ENST00000376929_length(transcript)=2132nt_BP=296nt
AGCGTGGCGCTGGCTCCCGGAATATGGAGCCCTGGGCGCGGGGGCGGCGTGTCAGGTGGTTGCGGAGCTGGTAAGAATCATATTCTAAGA
ACTCAGCCACTCAGGTATCCACCATGGTGCTGGGTCCTGAACAGAAGATGTCAGATGACAGTGTTTCTGGAGATCATGGGGAGTCTGCCA
GTCTTGGTAACATCAACCCTGCCTATAGTAATCCCTCTCTTTCACAGTCCCCTGGGGACTCAGAGGAGTACTTCGCCACTTACTTTAATG
AGAAGATCTCCATTCCTGAGGAGGAGGAACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATGACTGGACCCATCTGTCTTCAAAAG
AAGTGGACCCGTCTACAGGTGAACTCCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAGGAGGGACCCA
CAGGGCTGAAGGAAGCTGCCTTGTACCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGTCCCTCTCCCAGATGCTGTCCATGG
GCTTCTCTGATGAAGGCGGCTGGCTCACCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGGCTCTGGACACCATCCAGTATTCAA
AGCATCCCCCGCCGTTGTGACCACTTTTGCCCACCTCTTCTGCGTGCCCCTCTTCTGTCTCATAGTTGTGTTAAGCTTGCGTAGAATTGC
AGGTCTCTGTACGGGCCAGTTTCTCTGCCTTCTTCCAGGATCAGGGGTTAGGGTGCAAGAAGCCATTTAGGGCAGCAAAACAAGTGACAT
GAAGGGAGGGTCCCTGTGTGTGTGTGTGCTGATGTTTCCTGGGTGCCCTGGCTCCTTGCAGCAGGGCTGGGCCTGCGAGACCCAAGGCTC
ACTGCAGCGCGCTCCTGACCCCTCCCTGCAGGGGCTACGTTAGCAGCCCAGCACATAGCTTGCCTAATGGCTTTCACTTTCTCTTTTGTT
TTAAATGACTCATAGGTCCCTGACATTTAGTTGATTATTTTCTGCTACAGACCTGGTACACTCTGATTTTAGATAAAGTAAGCCTAGGTG
TTGTCAGCAGGCAGGCTGGGGAGGCCAGTGTTGTGGGCTTCCTGCTGGGACTGAGAAGGCTCACGAAGGGCATCCGCAATGTTGGTTTCA
CTGAGAGCTGCCTCCTGGTCTCTTCACCACTGTAGTTCTCTCATTTCCAAACCATCAGCTGCTTTTAAAATAAGATCTCTTTGTAGCCAT
CCTGTTAAATTTGTAAACAATCTAATTAAATGGCATCAGCACTTTAACCAATGACGTTTGCATAGAGAGAAATGATTGACAGTAAGTTTA
TTGTTAATGGTTCTTACAGAGTATCTTTAAAAGTGCCTTAGGGGAACCCTGTCCCTCCTAACAAGTGTATCTCGATTAATAACCTGCCAG
TCCCAGATCACACATCATCATCGAAGTCTTCCCCAGTTATAAAGAGGTCACATAGTCGTGTGGGTCGAGGATTCTGTGCCTCCAGGACCA
GGGGCCCACCCTCTGCCCAGGGAGTCCTTGCGTCCCATGAGGTCTTCCCGCAAGGCCTCTCAGACCCAGATGTGACGGGGTGTGTGGCCC
GAGGAAGCTGGACAGCGGCAGTGGGCCTGCTGAGGCCTTCTCTTGAGGCCTGTGCTCTGGGGGTCCCTTGCTTAGCCTGTGCTGGACCAG
CTGGCCTGGGGTCCCTCTGAAGAGACCTTGGCTGCTCACTGTCCACATGTGAACTTTTTCTAGGTGGCAGGACAAATTGCGCCCATTTAG
AGGATGTGGCTGTAACCTGCTGGATGGGACTCCATAGCTCCTTCCCAGGACCCCTCAGCTCCCCGGCACTGCAGTCTGCAGAGTTCTCCT
GGAGGCAGGGGCTGCTGCCTTGTTTCACCTTCCATGTCAGGCCAGCCTGTCCCTGAAAGAGAAGATGGCCATGCCCTCCATGTGTAAGAA
CAATGCCAGGGCCCAGGAGGACCGCCTGCCCTGCCTGGGCCTTGGCTGGGCCTCTGGTTCTGACACTTTCTGCTGGAAGCTGTCAGGCTG

>82206_82206_2_SLC11A2-SQSTM1_SLC11A2_chr12_51402258_ENST00000262052_SQSTM1_chr5_179260586_ENST00000376929_length(amino acids)=182AA_BP=
MGPGIVLTHGGHGHLLFQGQAGLTWKVKQGSSPCLQENSADCSAGELRGPGKELWSPIQQVTATSSKWAQFVLPPRKSSHVDSEQPRSLQ
RDPRPAGPAQAKQGTPRAQASREGLSRPTAAVQLPRATHPVTSGSERPCGKTSWDARTPWAEGGPLVLEAQNPRPTRLCDLFITGEDFDD

--------------------------------------------------------------
>82206_82206_3_SLC11A2-SQSTM1_SLC11A2_chr12_51402258_ENST00000394904_SQSTM1_chr5_179260586_ENST00000376929_length(transcript)=2156nt_BP=320nt
ATATATAGAGGCAGGAGCTGGCATTGGGAAAGTCAAACTAGTTCTGCACCATGAGGAAGAAGCAGCTGAAGACGGAGGCAGCTCCACACT
GTGAACTAAAATCATATTCTAAGAACTCAGCCACTCAGGTATCCACCATGGTGCTGGGTCCTGAACAGAAGATGTCAGATGACAGTGTTT
CTGGAGATCATGGGGAGTCTGCCAGTCTTGGTAACATCAACCCTGCCTATAGTAATCCCTCTCTTTCACAGTCCCCTGGGGACTCAGAGG
AGTACTTCGCCACTTACTTTAATGAGAAGATCTCCATTCCTGAGGAGGAGGAACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATG
ACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACTCCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTC
TGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTACCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGT
CCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCTCACCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGG
CTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGACCACTTTTGCCCACCTCTTCTGCGTGCCCCTCTTCTGTCTCATAGT
TGTGTTAAGCTTGCGTAGAATTGCAGGTCTCTGTACGGGCCAGTTTCTCTGCCTTCTTCCAGGATCAGGGGTTAGGGTGCAAGAAGCCAT
TTAGGGCAGCAAAACAAGTGACATGAAGGGAGGGTCCCTGTGTGTGTGTGTGCTGATGTTTCCTGGGTGCCCTGGCTCCTTGCAGCAGGG
CTGGGCCTGCGAGACCCAAGGCTCACTGCAGCGCGCTCCTGACCCCTCCCTGCAGGGGCTACGTTAGCAGCCCAGCACATAGCTTGCCTA
ATGGCTTTCACTTTCTCTTTTGTTTTAAATGACTCATAGGTCCCTGACATTTAGTTGATTATTTTCTGCTACAGACCTGGTACACTCTGA
TTTTAGATAAAGTAAGCCTAGGTGTTGTCAGCAGGCAGGCTGGGGAGGCCAGTGTTGTGGGCTTCCTGCTGGGACTGAGAAGGCTCACGA
AGGGCATCCGCAATGTTGGTTTCACTGAGAGCTGCCTCCTGGTCTCTTCACCACTGTAGTTCTCTCATTTCCAAACCATCAGCTGCTTTT
AAAATAAGATCTCTTTGTAGCCATCCTGTTAAATTTGTAAACAATCTAATTAAATGGCATCAGCACTTTAACCAATGACGTTTGCATAGA
GAGAAATGATTGACAGTAAGTTTATTGTTAATGGTTCTTACAGAGTATCTTTAAAAGTGCCTTAGGGGAACCCTGTCCCTCCTAACAAGT
GTATCTCGATTAATAACCTGCCAGTCCCAGATCACACATCATCATCGAAGTCTTCCCCAGTTATAAAGAGGTCACATAGTCGTGTGGGTC
GAGGATTCTGTGCCTCCAGGACCAGGGGCCCACCCTCTGCCCAGGGAGTCCTTGCGTCCCATGAGGTCTTCCCGCAAGGCCTCTCAGACC
CAGATGTGACGGGGTGTGTGGCCCGAGGAAGCTGGACAGCGGCAGTGGGCCTGCTGAGGCCTTCTCTTGAGGCCTGTGCTCTGGGGGTCC
CTTGCTTAGCCTGTGCTGGACCAGCTGGCCTGGGGTCCCTCTGAAGAGACCTTGGCTGCTCACTGTCCACATGTGAACTTTTTCTAGGTG
GCAGGACAAATTGCGCCCATTTAGAGGATGTGGCTGTAACCTGCTGGATGGGACTCCATAGCTCCTTCCCAGGACCCCTCAGCTCCCCGG
CACTGCAGTCTGCAGAGTTCTCCTGGAGGCAGGGGCTGCTGCCTTGTTTCACCTTCCATGTCAGGCCAGCCTGTCCCTGAAAGAGAAGAT
GGCCATGCCCTCCATGTGTAAGAACAATGCCAGGGCCCAGGAGGACCGCCTGCCCTGCCTGGGCCTTGGCTGGGCCTCTGGTTCTGACAC

>82206_82206_3_SLC11A2-SQSTM1_SLC11A2_chr12_51402258_ENST00000394904_SQSTM1_chr5_179260586_ENST00000376929_length(amino acids)=207AA_BP=90
MRKKQLKTEAAPHCELKSYSKNSATQVSTMVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEEE
EQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWL

--------------------------------------------------------------
>82206_82206_4_SLC11A2-SQSTM1_SLC11A2_chr12_51402258_ENST00000545993_SQSTM1_chr5_179260586_ENST00000376929_length(transcript)=2118nt_BP=282nt
AGAGTACAAAGGGTTCCTGCTTGGTGGTTTTGCTGCAGCTTCAGAGTTTAGCCTGAACTGTGGCAGGATTTTGTAACTTGCACATTTTTT
GAGAAGTCTGATGGAGGTATAATGTCCACGGTCGATTATTTGAACAGTGTTTCTGGAGATCATGGGGAGTCTGCCAGTCTTGGTAACATC
AACCCTGCCTATAGTAATCCCTCTCTTTCACAGTCCCCTGGGGACTCAGAGGAGTACTTCGCCACTTACTTTAATGAGAAGATCTCCATT
CCTGAGGAGGAGGAACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATGACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCT
ACAGGTGAACTCCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAA
GCTGCCTTGTACCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGTCCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAA
GGCGGCTGGCTCACCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGGCTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCG
TTGTGACCACTTTTGCCCACCTCTTCTGCGTGCCCCTCTTCTGTCTCATAGTTGTGTTAAGCTTGCGTAGAATTGCAGGTCTCTGTACGG
GCCAGTTTCTCTGCCTTCTTCCAGGATCAGGGGTTAGGGTGCAAGAAGCCATTTAGGGCAGCAAAACAAGTGACATGAAGGGAGGGTCCC
TGTGTGTGTGTGTGCTGATGTTTCCTGGGTGCCCTGGCTCCTTGCAGCAGGGCTGGGCCTGCGAGACCCAAGGCTCACTGCAGCGCGCTC
CTGACCCCTCCCTGCAGGGGCTACGTTAGCAGCCCAGCACATAGCTTGCCTAATGGCTTTCACTTTCTCTTTTGTTTTAAATGACTCATA
GGTCCCTGACATTTAGTTGATTATTTTCTGCTACAGACCTGGTACACTCTGATTTTAGATAAAGTAAGCCTAGGTGTTGTCAGCAGGCAG
GCTGGGGAGGCCAGTGTTGTGGGCTTCCTGCTGGGACTGAGAAGGCTCACGAAGGGCATCCGCAATGTTGGTTTCACTGAGAGCTGCCTC
CTGGTCTCTTCACCACTGTAGTTCTCTCATTTCCAAACCATCAGCTGCTTTTAAAATAAGATCTCTTTGTAGCCATCCTGTTAAATTTGT
AAACAATCTAATTAAATGGCATCAGCACTTTAACCAATGACGTTTGCATAGAGAGAAATGATTGACAGTAAGTTTATTGTTAATGGTTCT
TACAGAGTATCTTTAAAAGTGCCTTAGGGGAACCCTGTCCCTCCTAACAAGTGTATCTCGATTAATAACCTGCCAGTCCCAGATCACACA
TCATCATCGAAGTCTTCCCCAGTTATAAAGAGGTCACATAGTCGTGTGGGTCGAGGATTCTGTGCCTCCAGGACCAGGGGCCCACCCTCT
GCCCAGGGAGTCCTTGCGTCCCATGAGGTCTTCCCGCAAGGCCTCTCAGACCCAGATGTGACGGGGTGTGTGGCCCGAGGAAGCTGGACA
GCGGCAGTGGGCCTGCTGAGGCCTTCTCTTGAGGCCTGTGCTCTGGGGGTCCCTTGCTTAGCCTGTGCTGGACCAGCTGGCCTGGGGTCC
CTCTGAAGAGACCTTGGCTGCTCACTGTCCACATGTGAACTTTTTCTAGGTGGCAGGACAAATTGCGCCCATTTAGAGGATGTGGCTGTA
ACCTGCTGGATGGGACTCCATAGCTCCTTCCCAGGACCCCTCAGCTCCCCGGCACTGCAGTCTGCAGAGTTCTCCTGGAGGCAGGGGCTG
CTGCCTTGTTTCACCTTCCATGTCAGGCCAGCCTGTCCCTGAAAGAGAAGATGGCCATGCCCTCCATGTGTAAGAACAATGCCAGGGCCC
AGGAGGACCGCCTGCCCTGCCTGGGCCTTGGCTGGGCCTCTGGTTCTGACACTTTCTGCTGGAAGCTGTCAGGCTGGGACAGGCTTTGAT

>82206_82206_4_SLC11A2-SQSTM1_SLC11A2_chr12_51402258_ENST00000545993_SQSTM1_chr5_179260586_ENST00000376929_length(amino acids)=192AA_BP=75
MWQDFVTCTFFEKSDGGIMSTVDYLNSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEEEEQMESDNCSGGDDDW
THLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAAL

--------------------------------------------------------------
>82206_82206_5_SLC11A2-SQSTM1_SLC11A2_chr12_51402258_ENST00000547688_SQSTM1_chr5_179260586_ENST00000376929_length(transcript)=2348nt_BP=512nt
CCCTTTCAACCACTGGCACTCACAGGCTTGCCACCTACTCTTGCTCCTGCCAAATGGTCAAAGATGAAATCTGATTAGGCTTTGGAGGGC
GTGGTTTGCCTCTTGAAATTCCTTGCTCGTCTTTAGAAAGCTGTGTTGCTTAGAGCACCCAAAAGTGCCCTTTATCTAACTGAGGGAGGC
GCACTTGTCTTCATATATAGAGGCAGGAGCTGGCATTGGGAAAGTCAAACTAGTTCTGCACCATGAGGAAGAAGCAGCTGAAGACGGAGG
CAGCTCCACACTGTGAACTAAAATCATATTCTAAGAACTCAGCCACTCAGGTATCCACCATGGTGCTGGGTCCTGAACAGAAGATGTCAG
ATGACAGTGTTTCTGGAGATCATGGGGAGTCTGCCAGTCTTGGTAACATCAACCCTGCCTATAGTAATCCCTCTCTTTCACAGTCCCCTG
GGGACTCAGAGGAGTACTTCGCCACTTACTTTAATGAGAAGATCTCCATTCCTGAGGAGGAGGAACAGATGGAGTCGGATAACTGTTCAG
GAGGAGATGATGACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACTCCAGTCCCTACAGATGCCAGAATCCGAAG
GGCCAAGCTCTCTGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTACCCACATCTCCCGCCAGAGGCTGACCCGC
GGCTGATTGAGTCCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCTCACCAGGCTCCTGCAGACCAAGAACTATG
ACATCGGAGCGGCTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGACCACTTTTGCCCACCTCTTCTGCGTGCCCCTCTT
CTGTCTCATAGTTGTGTTAAGCTTGCGTAGAATTGCAGGTCTCTGTACGGGCCAGTTTCTCTGCCTTCTTCCAGGATCAGGGGTTAGGGT
GCAAGAAGCCATTTAGGGCAGCAAAACAAGTGACATGAAGGGAGGGTCCCTGTGTGTGTGTGTGCTGATGTTTCCTGGGTGCCCTGGCTC
CTTGCAGCAGGGCTGGGCCTGCGAGACCCAAGGCTCACTGCAGCGCGCTCCTGACCCCTCCCTGCAGGGGCTACGTTAGCAGCCCAGCAC
ATAGCTTGCCTAATGGCTTTCACTTTCTCTTTTGTTTTAAATGACTCATAGGTCCCTGACATTTAGTTGATTATTTTCTGCTACAGACCT
GGTACACTCTGATTTTAGATAAAGTAAGCCTAGGTGTTGTCAGCAGGCAGGCTGGGGAGGCCAGTGTTGTGGGCTTCCTGCTGGGACTGA
GAAGGCTCACGAAGGGCATCCGCAATGTTGGTTTCACTGAGAGCTGCCTCCTGGTCTCTTCACCACTGTAGTTCTCTCATTTCCAAACCA
TCAGCTGCTTTTAAAATAAGATCTCTTTGTAGCCATCCTGTTAAATTTGTAAACAATCTAATTAAATGGCATCAGCACTTTAACCAATGA
CGTTTGCATAGAGAGAAATGATTGACAGTAAGTTTATTGTTAATGGTTCTTACAGAGTATCTTTAAAAGTGCCTTAGGGGAACCCTGTCC
CTCCTAACAAGTGTATCTCGATTAATAACCTGCCAGTCCCAGATCACACATCATCATCGAAGTCTTCCCCAGTTATAAAGAGGTCACATA
GTCGTGTGGGTCGAGGATTCTGTGCCTCCAGGACCAGGGGCCCACCCTCTGCCCAGGGAGTCCTTGCGTCCCATGAGGTCTTCCCGCAAG
GCCTCTCAGACCCAGATGTGACGGGGTGTGTGGCCCGAGGAAGCTGGACAGCGGCAGTGGGCCTGCTGAGGCCTTCTCTTGAGGCCTGTG
CTCTGGGGGTCCCTTGCTTAGCCTGTGCTGGACCAGCTGGCCTGGGGTCCCTCTGAAGAGACCTTGGCTGCTCACTGTCCACATGTGAAC
TTTTTCTAGGTGGCAGGACAAATTGCGCCCATTTAGAGGATGTGGCTGTAACCTGCTGGATGGGACTCCATAGCTCCTTCCCAGGACCCC
TCAGCTCCCCGGCACTGCAGTCTGCAGAGTTCTCCTGGAGGCAGGGGCTGCTGCCTTGTTTCACCTTCCATGTCAGGCCAGCCTGTCCCT
GAAAGAGAAGATGGCCATGCCCTCCATGTGTAAGAACAATGCCAGGGCCCAGGAGGACCGCCTGCCCTGCCTGGGCCTTGGCTGGGCCTC
TGGTTCTGACACTTTCTGCTGGAAGCTGTCAGGCTGGGACAGGCTTTGATTTTGAGGGTTAGCAAGACAAAGCAAATAAATGCCTTCCAC

>82206_82206_5_SLC11A2-SQSTM1_SLC11A2_chr12_51402258_ENST00000547688_SQSTM1_chr5_179260586_ENST00000376929_length(amino acids)=207AA_BP=90
MRKKQLKTEAAPHCELKSYSKNSATQVSTMVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEEE
EQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SLC11A2-SQSTM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000036071847347_352239.0357.0KEAP1
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000037692969347_352239.0357.0KEAP1
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000038980558347_352323.0441.0KEAP1
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000040287458347_352239.0357.0KEAP1
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000036071847269_440239.0357.0NTRK1
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000037692969269_440239.0357.0NTRK1
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000040287458269_440239.0357.0NTRK1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000036071847122_224239.0357.0GABRR3
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000037692969122_224239.0357.0GABRR3
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000038980558122_224323.0441.0GABRR3
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000040287458122_224239.0357.0GABRR3
TgeneSQSTM1chr12:51402258chr5:179260586ENST00000360718472_50239.0357.0LCK
TgeneSQSTM1chr12:51402258chr5:179260586ENST00000376929692_50239.0357.0LCK
TgeneSQSTM1chr12:51402258chr5:179260586ENST00000389805582_50323.0441.0LCK
TgeneSQSTM1chr12:51402258chr5:179260586ENST00000402874582_50239.0357.0LCK
TgeneSQSTM1chr12:51402258chr5:179260586ENST0000038980558269_440323.0441.0NTRK1
TgeneSQSTM1chr12:51402258chr5:179260586ENST000003607184750_80239.0357.0PAWR
TgeneSQSTM1chr12:51402258chr5:179260586ENST000003769296950_80239.0357.0PAWR
TgeneSQSTM1chr12:51402258chr5:179260586ENST000003898055850_80323.0441.0PAWR
TgeneSQSTM1chr12:51402258chr5:179260586ENST000004028745850_80239.0357.0PAWR
TgeneSQSTM1chr12:51402258chr5:179260586ENST000003607184743_107239.0357.0PRKCZ and dimerization
TgeneSQSTM1chr12:51402258chr5:179260586ENST000003769296943_107239.0357.0PRKCZ and dimerization
TgeneSQSTM1chr12:51402258chr5:179260586ENST000003898055843_107323.0441.0PRKCZ and dimerization
TgeneSQSTM1chr12:51402258chr5:179260586ENST000004028745843_107239.0357.0PRKCZ and dimerization


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SLC11A2-SQSTM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SLC11A2-SQSTM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource