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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SLC1A3-FYB (FusionGDB2 ID:82391)

Fusion Gene Summary for SLC1A3-FYB

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC1A3-FYB
Fusion gene ID: 82391
HgeneTgene
Gene symbol

SLC1A3

FYB

Gene ID

6507

2533

Gene namesolute carrier family 1 member 3FYN binding protein 1
SynonymsEA6|EAAT1|GLAST|GLAST1ADAP|FYB|PRO0823|SLAP-130|SLAP130|THC3
Cytomap

5p13.2

5p13.1

Type of geneprotein-codingprotein-coding
Descriptionexcitatory amino acid transporter 1GLAST-1sodium-dependent glutamate/aspartate transporter 1solute carrier family 1 (glial high affinity glutamate transporter), member 3FYN-binding protein 1FYB-120/130FYN-T-binding proteinFYN-binding proteinSLP-76-associated phosphoproteinadhesion and degranulation-promoting adaptor proteinp120/p130
Modification date2020032020200313
UniProtAcc.

O15117

Ensembl transtripts involved in fusion geneENST00000506725, ENST00000265113, 
ENST00000381918, 		ENST00000351578, 
ENST00000505428, ENST00000512982, 
ENST00000515010, ENST00000540520, 
ENST00000503065, 
Fusion gene scores* DoF score12 X 10 X 6=72014 X 11 X 6=924
# samples 1415
** MAII scorelog2(14/720*10)=-2.36257007938471
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/924*10)=-2.62293035092018
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC1A3 [Title/Abstract] AND FYB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSLC1A3(36608706)-FYB(39110491), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSLC1A3

GO:0015813

L-glutamate transmembrane transport

26690923

HgeneSLC1A3

GO:0051938

L-glutamate import

7521911

HgeneSLC1A3

GO:0070779

D-aspartate import across plasma membrane

7521911

HgeneSLC1A3

GO:0071805

potassium ion transmembrane transport

20477940

HgeneSLC1A3

GO:0098712

L-glutamate import across plasma membrane

26690923

HgeneSLC1A3

GO:0140009

L-aspartate import across plasma membrane

20477940

HgeneSLC1A3

GO:1902476

chloride transmembrane transport

20477940


check buttonFusion gene breakpoints across SLC1A3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FYB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-61-1998-01ASLC1A3chr5

36608706

+FYBchr5

39110491

-


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Fusion Gene ORF analysis for SLC1A3-FYB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000506725ENST00000351578SLC1A3chr5

36608706

+FYBchr5

39110491

-
3UTR-3CDSENST00000506725ENST00000505428SLC1A3chr5

36608706

+FYBchr5

39110491

-
3UTR-3CDSENST00000506725ENST00000512982SLC1A3chr5

36608706

+FYBchr5

39110491

-
3UTR-3CDSENST00000506725ENST00000515010SLC1A3chr5

36608706

+FYBchr5

39110491

-
3UTR-3CDSENST00000506725ENST00000540520SLC1A3chr5

36608706

+FYBchr5

39110491

-
3UTR-intronENST00000506725ENST00000503065SLC1A3chr5

36608706

+FYBchr5

39110491

-
5CDS-intronENST00000265113ENST00000503065SLC1A3chr5

36608706

+FYBchr5

39110491

-
5CDS-intronENST00000381918ENST00000503065SLC1A3chr5

36608706

+FYBchr5

39110491

-
In-frameENST00000265113ENST00000351578SLC1A3chr5

36608706

+FYBchr5

39110491

-
In-frameENST00000265113ENST00000505428SLC1A3chr5

36608706

+FYBchr5

39110491

-
In-frameENST00000265113ENST00000512982SLC1A3chr5

36608706

+FYBchr5

39110491

-
In-frameENST00000265113ENST00000515010SLC1A3chr5

36608706

+FYBchr5

39110491

-
In-frameENST00000265113ENST00000540520SLC1A3chr5

36608706

+FYBchr5

39110491

-
In-frameENST00000381918ENST00000351578SLC1A3chr5

36608706

+FYBchr5

39110491

-
In-frameENST00000381918ENST00000505428SLC1A3chr5

36608706

+FYBchr5

39110491

-
In-frameENST00000381918ENST00000512982SLC1A3chr5

36608706

+FYBchr5

39110491

-
In-frameENST00000381918ENST00000515010SLC1A3chr5

36608706

+FYBchr5

39110491

-
In-frameENST00000381918ENST00000540520SLC1A3chr5

36608706

+FYBchr5

39110491

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000265113SLC1A3chr536608706+ENST00000351578FYBchr539110491-295365747674589
ENST00000265113SLC1A3chr536608706+ENST00000515010FYBchr539110491-90565747674589
ENST00000265113SLC1A3chr536608706+ENST00000505428FYBchr539110491-88765747674589
ENST00000265113SLC1A3chr536608706+ENST00000512982FYBchr539110491-88765747674589
ENST00000265113SLC1A3chr536608706+ENST00000540520FYBchr539110491-88765747674589
ENST00000381918SLC1A3chr536608706+ENST00000351578FYBchr539110491-25722769536489
ENST00000381918SLC1A3chr536608706+ENST00000515010FYBchr539110491-5242769536489
ENST00000381918SLC1A3chr536608706+ENST00000505428FYBchr539110491-5062769536489
ENST00000381918SLC1A3chr536608706+ENST00000512982FYBchr539110491-5062769536489
ENST00000381918SLC1A3chr536608706+ENST00000540520FYBchr539110491-5062769536489

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265113ENST00000351578SLC1A3chr536608706+FYBchr539110491-0.0485705030.9514295
ENST00000265113ENST00000515010SLC1A3chr536608706+FYBchr539110491-0.0265317950.9734682
ENST00000265113ENST00000505428SLC1A3chr536608706+FYBchr539110491-0.026303120.9736969
ENST00000265113ENST00000512982SLC1A3chr536608706+FYBchr539110491-0.026303120.9736969
ENST00000265113ENST00000540520SLC1A3chr536608706+FYBchr539110491-0.026303120.9736969
ENST00000381918ENST00000351578SLC1A3chr536608706+FYBchr539110491-0.172438010.82756203
ENST00000381918ENST00000515010SLC1A3chr536608706+FYBchr539110491-0.038521690.96147835
ENST00000381918ENST00000505428SLC1A3chr536608706+FYBchr539110491-0.039011950.96098804
ENST00000381918ENST00000512982SLC1A3chr536608706+FYBchr539110491-0.039011950.96098804
ENST00000381918ENST00000540520SLC1A3chr536608706+FYBchr539110491-0.039011950.96098804

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Fusion Genomic Features for SLC1A3-FYB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SLC1A3-FYB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:36608706/chr5:39110491)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FYB

O15117

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells (By similarity). May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton (PubMed:10747096, PubMed:16980616). Modulates the expression of IL2 (By similarity). Involved in platelet activation (By similarity). Prevents the degradation of SKAP1 and SKAP2 (PubMed:15849195). May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells (By similarity). {ECO:0000250|UniProtKB:D3ZIE4, ECO:0000250|UniProtKB:O35601, ECO:0000269|PubMed:10747096, ECO:0000269|PubMed:15849195, ECO:0000269|PubMed:16980616}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+2101_4760543.0Topological domainCytoplasmic
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+181_4760498.0Topological domainCytoplasmic

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210346_37660543.0IntramembraneDiscontinuously helical
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210426_45960543.0IntramembraneDiscontinuously helical
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18346_37660498.0IntramembraneDiscontinuously helical
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18426_45960498.0IntramembraneDiscontinuously helical
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210363_36560543.0RegionAspartate binding
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210443_44760543.0RegionAspartate binding
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18363_36560498.0RegionAspartate binding
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18443_44760498.0RegionAspartate binding
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210109_12260543.0Topological domainCytoplasmic
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210146_23660543.0Topological domainExtracellular
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210261_26960543.0Topological domainCytoplasmic
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210298_31860543.0Topological domainExtracellular
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210341_34560543.0Topological domainCytoplasmic
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210377_38560543.0Topological domainCytoplasmic
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210413_42560543.0Topological domainExtracellular
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210460_47260543.0Topological domainExtracellular
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210495_54260543.0Topological domainCytoplasmic
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+21069_8660543.0Topological domainExtracellular
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18109_12260498.0Topological domainCytoplasmic
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18146_23660498.0Topological domainExtracellular
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18261_26960498.0Topological domainCytoplasmic
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18298_31860498.0Topological domainExtracellular
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18341_34560498.0Topological domainCytoplasmic
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18377_38560498.0Topological domainCytoplasmic
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18413_42560498.0Topological domainExtracellular
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18460_47260498.0Topological domainExtracellular
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18495_54260498.0Topological domainCytoplasmic
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+1869_8660498.0Topological domainExtracellular
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210123_14560543.0TransmembraneHelical%3B Name%3D3
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210237_26060543.0TransmembraneHelical%3B Name%3D4
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210270_29760543.0TransmembraneHelical%3B Name%3D5
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210319_34060543.0TransmembraneHelical%3B Name%3D6
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210386_41260543.0TransmembraneHelical%3B Name%3D7
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+210473_49460543.0TransmembraneHelical%3B Name%3D8
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+21048_6860543.0TransmembraneHelical%3B Name%3D1
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000265113+21087_10860543.0TransmembraneHelical%3B Name%3D2
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18123_14560498.0TransmembraneHelical%3B Name%3D3
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18237_26060498.0TransmembraneHelical%3B Name%3D4
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18270_29760498.0TransmembraneHelical%3B Name%3D5
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18319_34060498.0TransmembraneHelical%3B Name%3D6
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18386_41260498.0TransmembraneHelical%3B Name%3D7
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+18473_49460498.0TransmembraneHelical%3B Name%3D8
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+1848_6860498.0TransmembraneHelical%3B Name%3D1
HgeneSLC1A3chr5:36608706chr5:39110491ENST00000381918+1887_10860498.0TransmembraneHelical%3B Name%3D2
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418456_507754784.0Coiled coilOntology_term=ECO:0000255
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519456_507800830.0Coiled coilOntology_term=ECO:0000255
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519456_507800830.0Coiled coilOntology_term=ECO:0000255
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317456_507754784.0Coiled coilOntology_term=ECO:0000255
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519456_507810840.0Coiled coilOntology_term=ECO:0000255
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418355_360754784.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418393_397754784.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418617_620754784.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519355_360800830.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519393_397800830.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519617_620800830.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519355_360800830.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519393_397800830.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519617_620800830.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317355_360754784.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317393_397754784.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317617_620754784.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519355_360810840.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519393_397810840.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519617_620810840.0Compositional biasNote=Poly-Pro
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418511_572754784.0DomainSH3 1
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418700_768754784.0DomainSH3 2
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519511_572800830.0DomainSH3 1
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519700_768800830.0DomainSH3 2
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519511_572800830.0DomainSH3 1
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519700_768800830.0DomainSH3 2
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317511_572754784.0DomainSH3 1
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317700_768754784.0DomainSH3 2
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519511_572810840.0DomainSH3 1
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519700_768810840.0DomainSH3 2
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418462_465754784.0MotifSH2-binding
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418469_505754784.0MotifNuclear localization signal
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418595_598754784.0MotifNote=SH2-binding%3B to LCP2
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418625_628754784.0MotifNote=SH2-binding%3B to FYN
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418674_700754784.0MotifNuclear localization signal
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519462_465800830.0MotifSH2-binding
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519469_505800830.0MotifNuclear localization signal
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519595_598800830.0MotifNote=SH2-binding%3B to LCP2
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519625_628800830.0MotifNote=SH2-binding%3B to FYN
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519674_700800830.0MotifNuclear localization signal
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519462_465800830.0MotifSH2-binding
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519469_505800830.0MotifNuclear localization signal
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519595_598800830.0MotifNote=SH2-binding%3B to LCP2
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519625_628800830.0MotifNote=SH2-binding%3B to FYN
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519674_700800830.0MotifNuclear localization signal
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317462_465754784.0MotifSH2-binding
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317469_505754784.0MotifNuclear localization signal
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317595_598754784.0MotifNote=SH2-binding%3B to LCP2
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317625_628754784.0MotifNote=SH2-binding%3B to FYN
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317674_700754784.0MotifNuclear localization signal
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519462_465810840.0MotifSH2-binding
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519469_505810840.0MotifNuclear localization signal
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519595_598810840.0MotifNote=SH2-binding%3B to LCP2
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519625_628810840.0MotifNote=SH2-binding%3B to FYN
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519674_700810840.0MotifNuclear localization signal


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Fusion Gene Sequence for SLC1A3-FYB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>82391_82391_1_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000265113_FYB_chr5_39110491_ENST00000351578_length(transcript)=2953nt_BP=657nt
GCTTTATTTTTCAATTCTTCCTAGTCCCGGTTTTGCATTTCTAATGACAGTGAACTGACAAAGCGTGAAAGTGGTCTAAGGAGCAAAACA
AAGCCAGCAAGCCTGCTTCTGGTGTGCCAAGATTAATCAATATTCCAGAAACCTCGGGGTTTCCCCCTCCTCCCTGTGCGGTTTCCATTC
CCCACTCCTCCTTTCCCGGGCACAGACTCCTCCCCTTTTCTTAAGTTGCCCTGATAGTAACTTGCAGTTTCAGAGCACATGCACACTGTC
AGGGCTAGCCTGCCTGCTTACGCGCGCTGCGGATTGTTGCTCCGTTGTACCTGCTGGGGAATTCACCTCGTTACTGCTTGATATCTTCCA
CCCCTTACAAAATCAGAAAAGTTGTGTTTTCTAATACCAAAGAGGAGGTTTGGCTTTCTGTGGGTGATTCCCAGACACTGAAGTGCAAAG
AAGAGACCCTCCTAGAAAAGTAAAATATGACTAAAAGCAATGGAGAAGAGCCCAAGATGGGGGGCAGGATGGAGAGATTCCAGCAGGGAG
TCCGTAAACGCACACTTTTGGCCAAGAAGAAAGTGCAGAACATTACAAAGGAGGATGTTAAAAGTTACCTGTTTCGGAATGCTTTTGTGC
TGCTCACAGTCACCGCTGTCATTGTGGATGGTTATGTCCTTCGGAGTTACCTAGCGGACAATGATGGAGAGATCTATGATGATATTGCTG
ATGGCTGCATCTATGACAATGACTAGCACTCAACTTTGGTCATTCTGCTGTGTTCATTAGGTGCCAATGTGAAGTCTGGATTTTAATTGG
CATGTTATTGGGTATCAAGAAAATTAATGCACAAAACCACTTATTATCATTTGTTATGAAATCCCAATTATCTTTACAAAGTGTTTAAAG
TTTGAACATAGAAAATAATCTCTCTGCTTAATTGTTAACTCAGAAGACTACATTAGTGAGATGTAAGAATTATTAAATATTCCATTTCCG
CTTTGGCTACAATTATGAAGAAGTTGAAGGTACTTCTTTTAGACCACCAGTAAATAATCCTCCTTCAAAAAATAAAAATAAAAGAAAAAG
GAAAATCATTCAGGAAGAAATGACCTGTCTAAAAAAACCTAAGGAAGAATAATAATATAAGAAAGGAAATTTAAAAACATTCCACAAGAA
GAAAAATTATTGTTTATACTTCTACTTATGGTTATATCTTATATTCTCTATTCAAGTGACCTGTCTTTTAAAAAGGCAGTGCTGTCTTAC
CTCTTGCTAGTGGGTTAAATGTTTTCAAAAATTATAGCAGTAGTAGAAGTTTTGTATAAAATTTGTCCTTATTTGTTAATTGTATATAAA
TGTTAATTATTTGATACGAATGTTATGCATTTAGTATGCACATTGAAGTCTAAACTGTAGAAGAGTCTAAAACAAGTTCTCTTTTTGCAG
ATTCACATACTAATGGTTTAATTCTGTGCTCTGTTTAAAGTACTATTATAACTAGAGTAGATCTGAATGAGGATAACCCTAAAATCATGA
GGAATGGAAGAATGGACCTTGAAACTACCTAGGCTTTTATGCATGGCACCTCTTTATAATGAAGACACTTTTTAAAGTTTTTGTTTTTGT
TTCAATTACCGCTAGATTTTTTTTTCTCTTTTTTTAAAATCCATTTTACTGGAAAGTTGGCCAGCAGAGGGAGTAGAAATTATTAAAATT
CTAGTGTTTGGATTGGGCCCTTCTCTAACAGTACATACTCATTCCCAAAGCAATCCAAAAACAAAATGTGAACCATTTGGGTTTCAAATG
TTAAGAACACTAAATAGCATGATTTAAAAAATGAAAAATGCTAACACCCAAGAAAAGAAGATATTAAGTGCTTTTTAACAACTCCTAGAG
TACAAAATGAGTACATCATAATGCTGGCTCTTCTACTAATGAACCATCGAGTGATATTGAATAAATTATTTATCTTCTCAGTTTCCTTAT
CTGTAAATTACAATATTAGACTAAGTAAGTTTTTCCAACTCTTCACTACCAATTACCTTAGGCTTTTATAATGCTCCGCCTACTTCAGTC
CCATGTTTCAGAAGCTTTTGTCTATTTTTTAAACTCATTGATTAAATAATGATTAATGCATTCTCCACATTTTAATATTGCAAAGGCCCA
TTGGAGTTTCTGAAGTGGCTCCACAGAATTGAAATAATTTCAAATAACTGTAAAGGAACTGAAAATCTTCACAGAGATGAAGTGGGGTTT
CCATTAGGTGCTTTGAAATTTGATAACAAATCATCAACTTCCACTGGTCAATATATAGATTTTGGGTGTCTGAGGCCCCAAGATTAGATG
CCACTAATCTCCAAAGATTCCCTCCAATTATGAAATATTTTAATGTCTACTTTTAGAGAGCACTAGCCAGTATATGACCATGTGATTAAT
TTCTTTTCACACTAGATAAAATTACCTGGTTCAAAAGTGGTTTTTGTTTATTAAATTTGGTAATAAATATATATAATACACAGACAGGAT
AGTTTTTATGCTGAAGTTTTTGGCCAGCTTTAGTTTGAGGACTCCTTGATAAGCTTGCTAAACTTTCAGAGTGCCCTGAGACACTTCCAG
CCATCCCTCCTCCTGCCTTCATTGGGGCAGACTTGCATTGCAGTCTGACAGTAATTTTTTTTCTGATTGAGAATTATGTAAATTCAGTAC
AATGTCAGTTTTTAAAAGTCAAAGTTAGATCAAGAGAATATTTCAGAGTTTTGGTTTACACATCAAGAAACAGACACACATACCTAGGAA
AGATTTACACAATAGATAATCATCTTAATGTGAAAGATATTTGAAGTATTAATTTTAATATATTAAATATGATTTCTGTTATAGTCTTCT

>82391_82391_1_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000265113_FYB_chr5_39110491_ENST00000351578_length(amino acids)=89AA_BP=59

--------------------------------------------------------------
>82391_82391_2_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000265113_FYB_chr5_39110491_ENST00000505428_length(transcript)=887nt_BP=657nt
GCTTTATTTTTCAATTCTTCCTAGTCCCGGTTTTGCATTTCTAATGACAGTGAACTGACAAAGCGTGAAAGTGGTCTAAGGAGCAAAACA
AAGCCAGCAAGCCTGCTTCTGGTGTGCCAAGATTAATCAATATTCCAGAAACCTCGGGGTTTCCCCCTCCTCCCTGTGCGGTTTCCATTC
CCCACTCCTCCTTTCCCGGGCACAGACTCCTCCCCTTTTCTTAAGTTGCCCTGATAGTAACTTGCAGTTTCAGAGCACATGCACACTGTC
AGGGCTAGCCTGCCTGCTTACGCGCGCTGCGGATTGTTGCTCCGTTGTACCTGCTGGGGAATTCACCTCGTTACTGCTTGATATCTTCCA
CCCCTTACAAAATCAGAAAAGTTGTGTTTTCTAATACCAAAGAGGAGGTTTGGCTTTCTGTGGGTGATTCCCAGACACTGAAGTGCAAAG
AAGAGACCCTCCTAGAAAAGTAAAATATGACTAAAAGCAATGGAGAAGAGCCCAAGATGGGGGGCAGGATGGAGAGATTCCAGCAGGGAG
TCCGTAAACGCACACTTTTGGCCAAGAAGAAAGTGCAGAACATTACAAAGGAGGATGTTAAAAGTTACCTGTTTCGGAATGCTTTTGTGC
TGCTCACAGTCACCGCTGTCATTGTGGATGGTTATGTCCTTCGGAGTTACCTAGCGGACAATGATGGAGAGATCTATGATGATATTGCTG
ATGGCTGCATCTATGACAATGACTAGCACTCAACTTTGGTCATTCTGCTGTGTTCATTAGGTGCCAATGTGAAGTCTGGATTTTAATTGG

>82391_82391_2_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000265113_FYB_chr5_39110491_ENST00000505428_length(amino acids)=89AA_BP=59

--------------------------------------------------------------
>82391_82391_3_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000265113_FYB_chr5_39110491_ENST00000512982_length(transcript)=887nt_BP=657nt
GCTTTATTTTTCAATTCTTCCTAGTCCCGGTTTTGCATTTCTAATGACAGTGAACTGACAAAGCGTGAAAGTGGTCTAAGGAGCAAAACA
AAGCCAGCAAGCCTGCTTCTGGTGTGCCAAGATTAATCAATATTCCAGAAACCTCGGGGTTTCCCCCTCCTCCCTGTGCGGTTTCCATTC
CCCACTCCTCCTTTCCCGGGCACAGACTCCTCCCCTTTTCTTAAGTTGCCCTGATAGTAACTTGCAGTTTCAGAGCACATGCACACTGTC
AGGGCTAGCCTGCCTGCTTACGCGCGCTGCGGATTGTTGCTCCGTTGTACCTGCTGGGGAATTCACCTCGTTACTGCTTGATATCTTCCA
CCCCTTACAAAATCAGAAAAGTTGTGTTTTCTAATACCAAAGAGGAGGTTTGGCTTTCTGTGGGTGATTCCCAGACACTGAAGTGCAAAG
AAGAGACCCTCCTAGAAAAGTAAAATATGACTAAAAGCAATGGAGAAGAGCCCAAGATGGGGGGCAGGATGGAGAGATTCCAGCAGGGAG
TCCGTAAACGCACACTTTTGGCCAAGAAGAAAGTGCAGAACATTACAAAGGAGGATGTTAAAAGTTACCTGTTTCGGAATGCTTTTGTGC
TGCTCACAGTCACCGCTGTCATTGTGGATGGTTATGTCCTTCGGAGTTACCTAGCGGACAATGATGGAGAGATCTATGATGATATTGCTG
ATGGCTGCATCTATGACAATGACTAGCACTCAACTTTGGTCATTCTGCTGTGTTCATTAGGTGCCAATGTGAAGTCTGGATTTTAATTGG

>82391_82391_3_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000265113_FYB_chr5_39110491_ENST00000512982_length(amino acids)=89AA_BP=59

--------------------------------------------------------------
>82391_82391_4_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000265113_FYB_chr5_39110491_ENST00000515010_length(transcript)=905nt_BP=657nt
GCTTTATTTTTCAATTCTTCCTAGTCCCGGTTTTGCATTTCTAATGACAGTGAACTGACAAAGCGTGAAAGTGGTCTAAGGAGCAAAACA
AAGCCAGCAAGCCTGCTTCTGGTGTGCCAAGATTAATCAATATTCCAGAAACCTCGGGGTTTCCCCCTCCTCCCTGTGCGGTTTCCATTC
CCCACTCCTCCTTTCCCGGGCACAGACTCCTCCCCTTTTCTTAAGTTGCCCTGATAGTAACTTGCAGTTTCAGAGCACATGCACACTGTC
AGGGCTAGCCTGCCTGCTTACGCGCGCTGCGGATTGTTGCTCCGTTGTACCTGCTGGGGAATTCACCTCGTTACTGCTTGATATCTTCCA
CCCCTTACAAAATCAGAAAAGTTGTGTTTTCTAATACCAAAGAGGAGGTTTGGCTTTCTGTGGGTGATTCCCAGACACTGAAGTGCAAAG
AAGAGACCCTCCTAGAAAAGTAAAATATGACTAAAAGCAATGGAGAAGAGCCCAAGATGGGGGGCAGGATGGAGAGATTCCAGCAGGGAG
TCCGTAAACGCACACTTTTGGCCAAGAAGAAAGTGCAGAACATTACAAAGGAGGATGTTAAAAGTTACCTGTTTCGGAATGCTTTTGTGC
TGCTCACAGTCACCGCTGTCATTGTGGATGGTTATGTCCTTCGGAGTTACCTAGCGGACAATGATGGAGAGATCTATGATGATATTGCTG
ATGGCTGCATCTATGACAATGACTAGCACTCAACTTTGGTCATTCTGCTGTGTTCATTAGGTGCCAATGTGAAGTCTGGATTTTAATTGG
CATGTTATTGGGTATCAAGAAAATTAATGCACAAAACCACTTATTATCATTTGTTATGAAATCCCAATTATCTTTACAAAGTGTTTAAAG

>82391_82391_4_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000265113_FYB_chr5_39110491_ENST00000515010_length(amino acids)=89AA_BP=59

--------------------------------------------------------------
>82391_82391_5_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000265113_FYB_chr5_39110491_ENST00000540520_length(transcript)=887nt_BP=657nt
GCTTTATTTTTCAATTCTTCCTAGTCCCGGTTTTGCATTTCTAATGACAGTGAACTGACAAAGCGTGAAAGTGGTCTAAGGAGCAAAACA
AAGCCAGCAAGCCTGCTTCTGGTGTGCCAAGATTAATCAATATTCCAGAAACCTCGGGGTTTCCCCCTCCTCCCTGTGCGGTTTCCATTC
CCCACTCCTCCTTTCCCGGGCACAGACTCCTCCCCTTTTCTTAAGTTGCCCTGATAGTAACTTGCAGTTTCAGAGCACATGCACACTGTC
AGGGCTAGCCTGCCTGCTTACGCGCGCTGCGGATTGTTGCTCCGTTGTACCTGCTGGGGAATTCACCTCGTTACTGCTTGATATCTTCCA
CCCCTTACAAAATCAGAAAAGTTGTGTTTTCTAATACCAAAGAGGAGGTTTGGCTTTCTGTGGGTGATTCCCAGACACTGAAGTGCAAAG
AAGAGACCCTCCTAGAAAAGTAAAATATGACTAAAAGCAATGGAGAAGAGCCCAAGATGGGGGGCAGGATGGAGAGATTCCAGCAGGGAG
TCCGTAAACGCACACTTTTGGCCAAGAAGAAAGTGCAGAACATTACAAAGGAGGATGTTAAAAGTTACCTGTTTCGGAATGCTTTTGTGC
TGCTCACAGTCACCGCTGTCATTGTGGATGGTTATGTCCTTCGGAGTTACCTAGCGGACAATGATGGAGAGATCTATGATGATATTGCTG
ATGGCTGCATCTATGACAATGACTAGCACTCAACTTTGGTCATTCTGCTGTGTTCATTAGGTGCCAATGTGAAGTCTGGATTTTAATTGG

>82391_82391_5_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000265113_FYB_chr5_39110491_ENST00000540520_length(amino acids)=89AA_BP=59

--------------------------------------------------------------
>82391_82391_6_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000381918_FYB_chr5_39110491_ENST00000351578_length(transcript)=2572nt_BP=276nt
TTGTGTTTTCTAATACCAAAGAGGAGGTTTGGCTTTCTGTGGGTGATTCCCAGACACTGAAGTGCAAAGAAGAGACCCTCCTAGAAAAGT
AAAATATGACTAAAAGCAATGGAGAAGAGCCCAAGATGGGGGGCAGGATGGAGAGATTCCAGCAGGGAGTCCGTAAACGCACACTTTTGG
CCAAGAAGAAAGTGCAGAACATTACAAAGGAGGATGTTAAAAGTTACCTGTTTCGGAATGCTTTTGTGCTGCTCACAGTCACCGCTGTCA
TTGTGGATGGTTATGTCCTTCGGAGTTACCTAGCGGACAATGATGGAGAGATCTATGATGATATTGCTGATGGCTGCATCTATGACAATG
ACTAGCACTCAACTTTGGTCATTCTGCTGTGTTCATTAGGTGCCAATGTGAAGTCTGGATTTTAATTGGCATGTTATTGGGTATCAAGAA
AATTAATGCACAAAACCACTTATTATCATTTGTTATGAAATCCCAATTATCTTTACAAAGTGTTTAAAGTTTGAACATAGAAAATAATCT
CTCTGCTTAATTGTTAACTCAGAAGACTACATTAGTGAGATGTAAGAATTATTAAATATTCCATTTCCGCTTTGGCTACAATTATGAAGA
AGTTGAAGGTACTTCTTTTAGACCACCAGTAAATAATCCTCCTTCAAAAAATAAAAATAAAAGAAAAAGGAAAATCATTCAGGAAGAAAT
GACCTGTCTAAAAAAACCTAAGGAAGAATAATAATATAAGAAAGGAAATTTAAAAACATTCCACAAGAAGAAAAATTATTGTTTATACTT
CTACTTATGGTTATATCTTATATTCTCTATTCAAGTGACCTGTCTTTTAAAAAGGCAGTGCTGTCTTACCTCTTGCTAGTGGGTTAAATG
TTTTCAAAAATTATAGCAGTAGTAGAAGTTTTGTATAAAATTTGTCCTTATTTGTTAATTGTATATAAATGTTAATTATTTGATACGAAT
GTTATGCATTTAGTATGCACATTGAAGTCTAAACTGTAGAAGAGTCTAAAACAAGTTCTCTTTTTGCAGATTCACATACTAATGGTTTAA
TTCTGTGCTCTGTTTAAAGTACTATTATAACTAGAGTAGATCTGAATGAGGATAACCCTAAAATCATGAGGAATGGAAGAATGGACCTTG
AAACTACCTAGGCTTTTATGCATGGCACCTCTTTATAATGAAGACACTTTTTAAAGTTTTTGTTTTTGTTTCAATTACCGCTAGATTTTT
TTTTCTCTTTTTTTAAAATCCATTTTACTGGAAAGTTGGCCAGCAGAGGGAGTAGAAATTATTAAAATTCTAGTGTTTGGATTGGGCCCT
TCTCTAACAGTACATACTCATTCCCAAAGCAATCCAAAAACAAAATGTGAACCATTTGGGTTTCAAATGTTAAGAACACTAAATAGCATG
ATTTAAAAAATGAAAAATGCTAACACCCAAGAAAAGAAGATATTAAGTGCTTTTTAACAACTCCTAGAGTACAAAATGAGTACATCATAA
TGCTGGCTCTTCTACTAATGAACCATCGAGTGATATTGAATAAATTATTTATCTTCTCAGTTTCCTTATCTGTAAATTACAATATTAGAC
TAAGTAAGTTTTTCCAACTCTTCACTACCAATTACCTTAGGCTTTTATAATGCTCCGCCTACTTCAGTCCCATGTTTCAGAAGCTTTTGT
CTATTTTTTAAACTCATTGATTAAATAATGATTAATGCATTCTCCACATTTTAATATTGCAAAGGCCCATTGGAGTTTCTGAAGTGGCTC
CACAGAATTGAAATAATTTCAAATAACTGTAAAGGAACTGAAAATCTTCACAGAGATGAAGTGGGGTTTCCATTAGGTGCTTTGAAATTT
GATAACAAATCATCAACTTCCACTGGTCAATATATAGATTTTGGGTGTCTGAGGCCCCAAGATTAGATGCCACTAATCTCCAAAGATTCC
CTCCAATTATGAAATATTTTAATGTCTACTTTTAGAGAGCACTAGCCAGTATATGACCATGTGATTAATTTCTTTTCACACTAGATAAAA
TTACCTGGTTCAAAAGTGGTTTTTGTTTATTAAATTTGGTAATAAATATATATAATACACAGACAGGATAGTTTTTATGCTGAAGTTTTT
GGCCAGCTTTAGTTTGAGGACTCCTTGATAAGCTTGCTAAACTTTCAGAGTGCCCTGAGACACTTCCAGCCATCCCTCCTCCTGCCTTCA
TTGGGGCAGACTTGCATTGCAGTCTGACAGTAATTTTTTTTCTGATTGAGAATTATGTAAATTCAGTACAATGTCAGTTTTTAAAAGTCA
AAGTTAGATCAAGAGAATATTTCAGAGTTTTGGTTTACACATCAAGAAACAGACACACATACCTAGGAAAGATTTACACAATAGATAATC
ATCTTAATGTGAAAGATATTTGAAGTATTAATTTTAATATATTAAATATGATTTCTGTTATAGTCTTCTGTATGGAATTTTGTCACTTAA

>82391_82391_6_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000381918_FYB_chr5_39110491_ENST00000351578_length(amino acids)=89AA_BP=59

--------------------------------------------------------------
>82391_82391_7_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000381918_FYB_chr5_39110491_ENST00000505428_length(transcript)=506nt_BP=276nt
TTGTGTTTTCTAATACCAAAGAGGAGGTTTGGCTTTCTGTGGGTGATTCCCAGACACTGAAGTGCAAAGAAGAGACCCTCCTAGAAAAGT
AAAATATGACTAAAAGCAATGGAGAAGAGCCCAAGATGGGGGGCAGGATGGAGAGATTCCAGCAGGGAGTCCGTAAACGCACACTTTTGG
CCAAGAAGAAAGTGCAGAACATTACAAAGGAGGATGTTAAAAGTTACCTGTTTCGGAATGCTTTTGTGCTGCTCACAGTCACCGCTGTCA
TTGTGGATGGTTATGTCCTTCGGAGTTACCTAGCGGACAATGATGGAGAGATCTATGATGATATTGCTGATGGCTGCATCTATGACAATG
ACTAGCACTCAACTTTGGTCATTCTGCTGTGTTCATTAGGTGCCAATGTGAAGTCTGGATTTTAATTGGCATGTTATTGGGTATCAAGAA

>82391_82391_7_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000381918_FYB_chr5_39110491_ENST00000505428_length(amino acids)=89AA_BP=59

--------------------------------------------------------------
>82391_82391_8_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000381918_FYB_chr5_39110491_ENST00000512982_length(transcript)=506nt_BP=276nt
TTGTGTTTTCTAATACCAAAGAGGAGGTTTGGCTTTCTGTGGGTGATTCCCAGACACTGAAGTGCAAAGAAGAGACCCTCCTAGAAAAGT
AAAATATGACTAAAAGCAATGGAGAAGAGCCCAAGATGGGGGGCAGGATGGAGAGATTCCAGCAGGGAGTCCGTAAACGCACACTTTTGG
CCAAGAAGAAAGTGCAGAACATTACAAAGGAGGATGTTAAAAGTTACCTGTTTCGGAATGCTTTTGTGCTGCTCACAGTCACCGCTGTCA
TTGTGGATGGTTATGTCCTTCGGAGTTACCTAGCGGACAATGATGGAGAGATCTATGATGATATTGCTGATGGCTGCATCTATGACAATG
ACTAGCACTCAACTTTGGTCATTCTGCTGTGTTCATTAGGTGCCAATGTGAAGTCTGGATTTTAATTGGCATGTTATTGGGTATCAAGAA

>82391_82391_8_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000381918_FYB_chr5_39110491_ENST00000512982_length(amino acids)=89AA_BP=59

--------------------------------------------------------------
>82391_82391_9_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000381918_FYB_chr5_39110491_ENST00000515010_length(transcript)=524nt_BP=276nt
TTGTGTTTTCTAATACCAAAGAGGAGGTTTGGCTTTCTGTGGGTGATTCCCAGACACTGAAGTGCAAAGAAGAGACCCTCCTAGAAAAGT
AAAATATGACTAAAAGCAATGGAGAAGAGCCCAAGATGGGGGGCAGGATGGAGAGATTCCAGCAGGGAGTCCGTAAACGCACACTTTTGG
CCAAGAAGAAAGTGCAGAACATTACAAAGGAGGATGTTAAAAGTTACCTGTTTCGGAATGCTTTTGTGCTGCTCACAGTCACCGCTGTCA
TTGTGGATGGTTATGTCCTTCGGAGTTACCTAGCGGACAATGATGGAGAGATCTATGATGATATTGCTGATGGCTGCATCTATGACAATG
ACTAGCACTCAACTTTGGTCATTCTGCTGTGTTCATTAGGTGCCAATGTGAAGTCTGGATTTTAATTGGCATGTTATTGGGTATCAAGAA

>82391_82391_9_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000381918_FYB_chr5_39110491_ENST00000515010_length(amino acids)=89AA_BP=59

--------------------------------------------------------------
>82391_82391_10_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000381918_FYB_chr5_39110491_ENST00000540520_length(transcript)=506nt_BP=276nt
TTGTGTTTTCTAATACCAAAGAGGAGGTTTGGCTTTCTGTGGGTGATTCCCAGACACTGAAGTGCAAAGAAGAGACCCTCCTAGAAAAGT
AAAATATGACTAAAAGCAATGGAGAAGAGCCCAAGATGGGGGGCAGGATGGAGAGATTCCAGCAGGGAGTCCGTAAACGCACACTTTTGG
CCAAGAAGAAAGTGCAGAACATTACAAAGGAGGATGTTAAAAGTTACCTGTTTCGGAATGCTTTTGTGCTGCTCACAGTCACCGCTGTCA
TTGTGGATGGTTATGTCCTTCGGAGTTACCTAGCGGACAATGATGGAGAGATCTATGATGATATTGCTGATGGCTGCATCTATGACAATG
ACTAGCACTCAACTTTGGTCATTCTGCTGTGTTCATTAGGTGCCAATGTGAAGTCTGGATTTTAATTGGCATGTTATTGGGTATCAAGAA

>82391_82391_10_SLC1A3-FYB_SLC1A3_chr5_36608706_ENST00000381918_FYB_chr5_39110491_ENST00000540520_length(amino acids)=89AA_BP=59

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SLC1A3-FYB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneFYBchr5:36608706chr5:39110491ENST000003515781418348_448754.3333333333334784.0SKAP1
TgeneFYBchr5:36608706chr5:39110491ENST000005054281519348_448800.3333333333334830.0SKAP1
TgeneFYBchr5:36608706chr5:39110491ENST000005129821519348_448800.3333333333334830.0SKAP1
TgeneFYBchr5:36608706chr5:39110491ENST000005150101317348_448754.3333333333334784.0SKAP1
TgeneFYBchr5:36608706chr5:39110491ENST000005405201519348_448810.3333333333334840.0SKAP1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SLC1A3-FYB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SLC1A3-FYB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource