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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SLC25A17-EPN3 (FusionGDB2 ID:82581)

Fusion Gene Summary for SLC25A17-EPN3

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC25A17-EPN3
Fusion gene ID: 82581
HgeneTgene
Gene symbol

SLC25A17

EPN3

Gene ID

10478

55040

Gene namesolute carrier family 25 member 17epsin 3
SynonymsPMP34-
Cytomap

22q13.2

17q21.33

Type of geneprotein-codingprotein-coding
Descriptionperoxisomal membrane protein PMP34solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17epsin-3EPS-15-interacting protein 3
Modification date2020031320200313
UniProtAcc.

Q9H201

Ensembl transtripts involved in fusion geneENST00000435456, ENST00000542412, 
ENST00000491545, ENST00000544408, 
ENST00000402844, 		ENST00000515028, 
ENST00000537145, ENST00000541226, 
ENST00000268933, 
Fusion gene scores* DoF score7 X 6 X 6=2523 X 4 X 3=36
# samples 93
** MAII scorelog2(9/252*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/36*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC25A17 [Title/Abstract] AND EPN3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSLC25A17(41215199)-EPN3(48616548), # samples:1
SLC25A17(41215199)-EPN3(48616245), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SLC25A17 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EPN3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRCTCGA-BP-5186-01ASLC25A17chr22

41215199

-EPN3chr17

48616245

+
ChimerDB4KIRCTCGA-BP-5186-01ASLC25A17chr22

41215199

-EPN3chr17

48616548

+


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Fusion Gene ORF analysis for SLC25A17-EPN3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000435456ENST00000515028SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5CDS-intronENST00000435456ENST00000515028SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5CDS-intronENST00000435456ENST00000537145SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5CDS-intronENST00000435456ENST00000537145SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5CDS-intronENST00000435456ENST00000541226SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5CDS-intronENST00000435456ENST00000541226SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5CDS-intronENST00000542412ENST00000515028SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5CDS-intronENST00000542412ENST00000515028SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5CDS-intronENST00000542412ENST00000537145SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5CDS-intronENST00000542412ENST00000537145SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5CDS-intronENST00000542412ENST00000541226SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5CDS-intronENST00000542412ENST00000541226SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5UTR-3CDSENST00000491545ENST00000268933SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5UTR-3CDSENST00000491545ENST00000268933SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5UTR-3CDSENST00000544408ENST00000268933SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5UTR-3CDSENST00000544408ENST00000268933SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5UTR-intronENST00000491545ENST00000515028SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5UTR-intronENST00000491545ENST00000515028SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5UTR-intronENST00000491545ENST00000537145SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5UTR-intronENST00000491545ENST00000537145SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5UTR-intronENST00000491545ENST00000541226SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5UTR-intronENST00000491545ENST00000541226SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5UTR-intronENST00000544408ENST00000515028SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5UTR-intronENST00000544408ENST00000515028SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5UTR-intronENST00000544408ENST00000537145SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5UTR-intronENST00000544408ENST00000537145SLC25A17chr22

41215199

-EPN3chr17

48616548

+
5UTR-intronENST00000544408ENST00000541226SLC25A17chr22

41215199

-EPN3chr17

48616245

+
5UTR-intronENST00000544408ENST00000541226SLC25A17chr22

41215199

-EPN3chr17

48616548

+
In-frameENST00000435456ENST00000268933SLC25A17chr22

41215199

-EPN3chr17

48616245

+
In-frameENST00000435456ENST00000268933SLC25A17chr22

41215199

-EPN3chr17

48616548

+
In-frameENST00000542412ENST00000268933SLC25A17chr22

41215199

-EPN3chr17

48616245

+
In-frameENST00000542412ENST00000268933SLC25A17chr22

41215199

-EPN3chr17

48616548

+
intron-3CDSENST00000402844ENST00000268933SLC25A17chr22

41215199

-EPN3chr17

48616245

+
intron-3CDSENST00000402844ENST00000268933SLC25A17chr22

41215199

-EPN3chr17

48616548

+
intron-intronENST00000402844ENST00000515028SLC25A17chr22

41215199

-EPN3chr17

48616245

+
intron-intronENST00000402844ENST00000515028SLC25A17chr22

41215199

-EPN3chr17

48616548

+
intron-intronENST00000402844ENST00000537145SLC25A17chr22

41215199

-EPN3chr17

48616245

+
intron-intronENST00000402844ENST00000537145SLC25A17chr22

41215199

-EPN3chr17

48616548

+
intron-intronENST00000402844ENST00000541226SLC25A17chr22

41215199

-EPN3chr17

48616245

+
intron-intronENST00000402844ENST00000541226SLC25A17chr22

41215199

-EPN3chr17

48616548

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000435456SLC25A17chr2241215199-ENST00000268933EPN3chr1748616548+2918188501324424
ENST00000542412SLC25A17chr2241215199-ENST00000268933EPN3chr1748616548+282393151229404
ENST00000435456SLC25A17chr2241215199-ENST00000268933EPN3chr1748616245+2999188501405451
ENST00000542412SLC25A17chr2241215199-ENST00000268933EPN3chr1748616245+290493151310431

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000435456ENST00000268933SLC25A17chr2241215199-EPN3chr1748616548+0.153871760.84612817
ENST00000542412ENST00000268933SLC25A17chr2241215199-EPN3chr1748616548+0.159546210.8404538
ENST00000435456ENST00000268933SLC25A17chr2241215199-EPN3chr1748616245+0.151883330.84811664
ENST00000542412ENST00000268933SLC25A17chr2241215199-EPN3chr1748616245+0.155679320.84432065

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Fusion Genomic Features for SLC25A17-EPN3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SLC25A17chr2241215198-EPN3chr1748616547+0.128836330.8711637
SLC25A17chr2241215198-EPN3chr1748616244+1.54E-060.99999845
SLC25A17chr2241215198-EPN3chr1748616547+0.128836330.8711637
SLC25A17chr2241215198-EPN3chr1748616244+1.54E-060.99999845

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SLC25A17-EPN3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:41215199/chr17:48616548)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EPN3

Q9H201

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-191_918308.0Topological domainNote=Cytoplasmic
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-191_918308.0Topological domainNote=Cytoplasmic
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210236_255227633.0DomainUIM 2
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210321_406227633.0RegionNote=5 X 3 AA repeats of [DE]-P-W
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210524_631227633.0RegionNote=3 X 3 AA repeats of N-P-F
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310321_406254633.0RegionNote=5 X 3 AA repeats of [DE]-P-W
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310524_631254633.0RegionNote=3 X 3 AA repeats of N-P-F
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210321_323227633.0RepeatNote=1
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210344_346227633.0RepeatNote=2
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210371_373227633.0RepeatNote=3
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210387_389227633.0RepeatNote=4
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210404_406227633.0RepeatNote=5
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210524_526227633.0RepeatNote=1
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210537_539227633.0RepeatNote=2
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210629_631227633.0RepeatNote=3
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310321_323254633.0RepeatNote=1
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310344_346254633.0RepeatNote=2
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310371_373254633.0RepeatNote=3
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310387_389254633.0RepeatNote=4
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310404_406254633.0RepeatNote=5
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310524_526254633.0RepeatNote=1
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310537_539254633.0RepeatNote=2
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310629_631254633.0RepeatNote=3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-19200_29418308.0RepeatNote=Solcar 3
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-197_9218308.0RepeatNote=Solcar 1
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-1999_19218308.0RepeatNote=Solcar 2
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-19200_29418308.0RepeatNote=Solcar 3
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-197_9218308.0RepeatNote=Solcar 1
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-1999_19218308.0RepeatNote=Solcar 2
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-19126_16018308.0Topological domainLumenal
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-19182_20218308.0Topological domainCytoplasmic
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-19224_28018308.0Topological domainLumenal
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-19302_30718308.0Topological domainNote=Cytoplasmic
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-1931_6618308.0Topological domainLumenal
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-1988_10418308.0Topological domainCytoplasmic
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-19126_16018308.0Topological domainLumenal
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-19182_20218308.0Topological domainCytoplasmic
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-19224_28018308.0Topological domainLumenal
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-19302_30718308.0Topological domainNote=Cytoplasmic
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-1931_6618308.0Topological domainLumenal
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-1988_10418308.0Topological domainCytoplasmic
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-19105_12518308.0TransmembraneHelical%3B Name%3D3
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-1910_3018308.0TransmembraneHelical%3B Name%3D1
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-19161_18118308.0TransmembraneHelical%3B Name%3D4
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-19203_22318308.0TransmembraneHelical%3B Name%3D5
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-19281_30118308.0TransmembraneHelical%3B Name%3D6
HgeneSLC25A17chr22:41215199chr17:48616245ENST00000435456-1967_8718308.0TransmembraneHelical%3B Name%3D2
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-19105_12518308.0TransmembraneHelical%3B Name%3D3
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-1910_3018308.0TransmembraneHelical%3B Name%3D1
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-19161_18118308.0TransmembraneHelical%3B Name%3D4
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-19203_22318308.0TransmembraneHelical%3B Name%3D5
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-19281_30118308.0TransmembraneHelical%3B Name%3D6
HgeneSLC25A17chr22:41215199chr17:48616548ENST00000435456-1967_8718308.0TransmembraneHelical%3B Name%3D2
TgeneEPN3chr22:41215199chr17:48616245ENST0000026893321012_144227633.0DomainENTH
TgeneEPN3chr22:41215199chr17:48616245ENST00000268933210209_228227633.0DomainUIM 1
TgeneEPN3chr22:41215199chr17:48616548ENST0000026893331012_144254633.0DomainENTH
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310209_228254633.0DomainUIM 1
TgeneEPN3chr22:41215199chr17:48616548ENST00000268933310236_255254633.0DomainUIM 2


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Fusion Gene Sequence for SLC25A17-EPN3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>82581_82581_1_SLC25A17-EPN3_SLC25A17_chr22_41215199_ENST00000435456_EPN3_chr17_48616245_ENST00000268933_length(transcript)=2999nt_BP=188nt
CTAGGGCAGGCGGGCGGGTTTGAGAGGGCGGGGATTGCGACTCTCACACCCTGAGCTCCGGTGCTCCTTTCCTAACTCCACTGGCTGCGG
CATCTGTGGGAAAAGTGTGGCTGGGTCTTCGAGGAGCCGCACCAATGGCTTCCGTGCTGTCCTACGAAAGCCTGGTCCACGCCGTGGCCG
GAGCCGTGCCTGTCCCCCCAGCCTCCCACAGGGACGAGGACCTGCAGCTGCAGCTGGCTCTGCGCCTGAGCCGGCAGGAGCACGAGAAGG
AGGTGAGGTCCTGGCAGGGTGATGGCTCCCCCATGGCCAATGGTGCAGGGGCCGTGGTCCACCATCAGCGGGACAGAGAGCCTGAGAGAG
AAGAGAGAAAGGAGGAGGAGAAGCTAAAAACCAGCCAGTCCTCCATCCTGGACTTGGCTGACATCTTCGTACCTGCCCTGGCCCCGCCCT
CCACACACTGCTCTGCTGACCCATGGGACATCCCAGGTTTTAGGCCGAACACAGAGGCCAGTGGATCCTCCTGGGGGCCTTCTGCAGACC
CCTGGTCTCCGATCCCCTCAGGAACCGTCCTGTCCCGAAGCCAGCCCTGGGATCTGACTCCCATGCTCTCCTCCTCTGAGCCCTGGGGCA
GGACCCCAGTGCTGCCTGCTGGGCCCCCCACCACAGACCCCTGGGCCCTGAACTCTCCCCACCACAAACTCCCCAGCACTGGGGCTGACC
CTTGGGGAGCCTCCCTGGAGACCTCCGACACACCTGGTGGTGCCTCGACCTTTGACCCATTTGCCAAACCTCCAGAATCCACAGAGACCA
AGGAGGGGCTGGAGCAGGCCCTGCCCTCTGGGAAGCCCAGCAGCCCTGTGGAGCTGGACCTGTTTGGAGACCCCAGCCCCAGTTCCAAGC
AAAATGGCACGAAGGAGCCAGATGCCCTGGACCTGGGCATACTAGGGGAAGCACTAACCCAGCCAAGCAAAGAGGCCCGAGCTTGCCGGA
CTCCCGAGTCCTTCCTGGGTCCCTCAGCTTCCTCCTTGGTCAACCTTGACTCGTTGGTCAAGGCACCCCAGGTTGCAAAGACCCGGAACC
CCTTCCTGACAGGTCTCAGCGCTCCGTCCCCCACCAACCCGTTCGGCGCGGGCGAGCCGGGCAGGCCGACGCTAAACCAGATGCGCACCG
GCTCGCCGGCGCTGGGCCTGGCAGGCGGGCCTGTGGGGGCGCCCCTGGGCTCCATGACCTACAGCGCCTCTCTGCCCCTCCCGCTCAGCA
GCGTGCCAGCTGGCTTGACCCTCCCCGCCTCGGTTAGCGTCTTCCCGCAGGCCGGAGCCTTCGCACCGCAGCCGCTGCTGCCCACGCCGA
GCTCAGCCGGGCCGCGGCCCCCGCCCCCGCAGACCGGCACCAACCCCTTCCTCTGAGCCCCGCCCCGTCCCATACCGGCCTGCGCCTGCG
CCGGACGCTCCGCGGCCCCGCCTCCGGACCCGGGGCTGGGCGGGGCGCCGGTGCTAGTGGAACGCCGAGCCAGTGGCGGCTGGTATCCCG
CGGCGGCTCTGGAAGCTGGACGCGGACCACGGCCCGGGAGCTAGAAACTGAACGCCCGCATAATAAAGACTGGAACCCTCGTTCTCAGCT
CTCACCAAGTGGACTTTTTGCGGGGTGTGGCGGCCGGGTCTCGACCACAGCGTGGATCACCGGCTGTTTAGGAAACTGCAGCTGCACAAC
GTGGGGTGCAAAACTGCCCCGCTTCCTTTACAGCTCTTCTCAACCCTCACCTCCATCCCCCGTCACCCAGGCACCTTCGCTTCCAGATGC
TGCCAGGCTGTCACTCAATTCGGTCATTTCATTCATTTATCACACATGGGCACTGGGGTTGGGCTAACAGCAAGAGACAATAGGCCTTTG
TTCCTATTTATTGGGTACTGCTTACGTGCTAAGCAGATCAGTTTATTTAATGCTTGCAACGACTCTCTGAGGTAGAAAATATTGTTAATT
CCGTTCAGGATCCCGGCTACATAATCTGTGGGGCTCAATACAAAATAAAAATGTAGGGGCTCCTTGTTCAAAATCGTATGAAGAATTTCA
AAACAGGGACAACAGAGCATGAAACCAAGCGCAAAGCCCACTGCAGTGCGATTGCACAGGTATCTCACCTTGCAGCCGGCACTACTCCCA
TTTTTCAGGCAAGGAAACCGTGGCTCAGAGAGGTTGAATGGCATGCTCAAAGTCACAAAGCTGGCATGGGGCGGGGCTGGAACTCAAGAG
TCAGACAGTCTGGCTCCAAGGCCTGGAGATCCCAGGCTGGGCCCCAGATTTAATTCAGCAAATATTGACTGACTGCTGTGGACAAAGTGC
TGGGCTCACCTTGGAGGGATCCAACCTCCAGGAGCTCGAGCGCAGCAGGGTAGACAAGCCAGGGGCACGTGATGCGGCTGTGGCAGAAGC
CAAGTGCAGGAGCTCCCAGGCTCCTTTGTTTTACTGAGTCACCTTAAATGTAACTCTGCCCTCTCCCTTGCTTCGCCAAGGCTAGCGAGA
AACTCAGTCTTAGCCACACAGGAGGAATCGGACCCCTTCTGGGGGTTTATGTGGAGTCTGGGAAACCAAGGGTGGGGTGAGGCCTGGTAC
TCAATCCAGGAGGGGCCCCTATGACCACCCTCGCCTGTTTTTCTTCTCAATGCTCCCTGATCACTGGACCACTGGACACTGATGTGTCCT
CAGTGCTTGGGGTCTGGCTCTGCAGGCAGCCTGCAGCCAGCCTCCATCCCCCTTTCAGGGACAAATGGCCTTCCACCAGAGTCGGTGAGT
GGAGAGGCACAATGCCACTCCCCTTCCTGAGGTGGGGGTAGGGGAAGGGAGTCCCACAATGCAGTTACAAACAGGATGGACAAGAACACC
TGCTCAGGAGTCAGACTTACAGGGTTCAAAGTTCTGCTCCAAGGTTTGACCCTAACAAGAATCACTTAGTAATAAGTGGTTATGCTCTGT

>82581_82581_1_SLC25A17-EPN3_SLC25A17_chr22_41215199_ENST00000435456_EPN3_chr17_48616245_ENST00000268933_length(amino acids)=451AA_BP=46
MSSGAPFLTPLAAASVGKVWLGLRGAAPMASVLSYESLVHAVAGAVPVPPASHRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAG
AVVHHQRDREPEREERKEEEKLKTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPW
DLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPV
ELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGA
GEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNPF

--------------------------------------------------------------
>82581_82581_2_SLC25A17-EPN3_SLC25A17_chr22_41215199_ENST00000435456_EPN3_chr17_48616548_ENST00000268933_length(transcript)=2918nt_BP=188nt
CTAGGGCAGGCGGGCGGGTTTGAGAGGGCGGGGATTGCGACTCTCACACCCTGAGCTCCGGTGCTCCTTTCCTAACTCCACTGGCTGCGG
CATCTGTGGGAAAAGTGTGGCTGGGTCTTCGAGGAGCCGCACCAATGGCTTCCGTGCTGTCCTACGAAAGCCTGGTCCACGCCGTGGCCG
GAGCCGTGGAGGTGAGGTCCTGGCAGGGTGATGGCTCCCCCATGGCCAATGGTGCAGGGGCCGTGGTCCACCATCAGCGGGACAGAGAGC
CTGAGAGAGAAGAGAGAAAGGAGGAGGAGAAGCTAAAAACCAGCCAGTCCTCCATCCTGGACTTGGCTGACATCTTCGTACCTGCCCTGG
CCCCGCCCTCCACACACTGCTCTGCTGACCCATGGGACATCCCAGGTTTTAGGCCGAACACAGAGGCCAGTGGATCCTCCTGGGGGCCTT
CTGCAGACCCCTGGTCTCCGATCCCCTCAGGAACCGTCCTGTCCCGAAGCCAGCCCTGGGATCTGACTCCCATGCTCTCCTCCTCTGAGC
CCTGGGGCAGGACCCCAGTGCTGCCTGCTGGGCCCCCCACCACAGACCCCTGGGCCCTGAACTCTCCCCACCACAAACTCCCCAGCACTG
GGGCTGACCCTTGGGGAGCCTCCCTGGAGACCTCCGACACACCTGGTGGTGCCTCGACCTTTGACCCATTTGCCAAACCTCCAGAATCCA
CAGAGACCAAGGAGGGGCTGGAGCAGGCCCTGCCCTCTGGGAAGCCCAGCAGCCCTGTGGAGCTGGACCTGTTTGGAGACCCCAGCCCCA
GTTCCAAGCAAAATGGCACGAAGGAGCCAGATGCCCTGGACCTGGGCATACTAGGGGAAGCACTAACCCAGCCAAGCAAAGAGGCCCGAG
CTTGCCGGACTCCCGAGTCCTTCCTGGGTCCCTCAGCTTCCTCCTTGGTCAACCTTGACTCGTTGGTCAAGGCACCCCAGGTTGCAAAGA
CCCGGAACCCCTTCCTGACAGGTCTCAGCGCTCCGTCCCCCACCAACCCGTTCGGCGCGGGCGAGCCGGGCAGGCCGACGCTAAACCAGA
TGCGCACCGGCTCGCCGGCGCTGGGCCTGGCAGGCGGGCCTGTGGGGGCGCCCCTGGGCTCCATGACCTACAGCGCCTCTCTGCCCCTCC
CGCTCAGCAGCGTGCCAGCTGGCTTGACCCTCCCCGCCTCGGTTAGCGTCTTCCCGCAGGCCGGAGCCTTCGCACCGCAGCCGCTGCTGC
CCACGCCGAGCTCAGCCGGGCCGCGGCCCCCGCCCCCGCAGACCGGCACCAACCCCTTCCTCTGAGCCCCGCCCCGTCCCATACCGGCCT
GCGCCTGCGCCGGACGCTCCGCGGCCCCGCCTCCGGACCCGGGGCTGGGCGGGGCGCCGGTGCTAGTGGAACGCCGAGCCAGTGGCGGCT
GGTATCCCGCGGCGGCTCTGGAAGCTGGACGCGGACCACGGCCCGGGAGCTAGAAACTGAACGCCCGCATAATAAAGACTGGAACCCTCG
TTCTCAGCTCTCACCAAGTGGACTTTTTGCGGGGTGTGGCGGCCGGGTCTCGACCACAGCGTGGATCACCGGCTGTTTAGGAAACTGCAG
CTGCACAACGTGGGGTGCAAAACTGCCCCGCTTCCTTTACAGCTCTTCTCAACCCTCACCTCCATCCCCCGTCACCCAGGCACCTTCGCT
TCCAGATGCTGCCAGGCTGTCACTCAATTCGGTCATTTCATTCATTTATCACACATGGGCACTGGGGTTGGGCTAACAGCAAGAGACAAT
AGGCCTTTGTTCCTATTTATTGGGTACTGCTTACGTGCTAAGCAGATCAGTTTATTTAATGCTTGCAACGACTCTCTGAGGTAGAAAATA
TTGTTAATTCCGTTCAGGATCCCGGCTACATAATCTGTGGGGCTCAATACAAAATAAAAATGTAGGGGCTCCTTGTTCAAAATCGTATGA
AGAATTTCAAAACAGGGACAACAGAGCATGAAACCAAGCGCAAAGCCCACTGCAGTGCGATTGCACAGGTATCTCACCTTGCAGCCGGCA
CTACTCCCATTTTTCAGGCAAGGAAACCGTGGCTCAGAGAGGTTGAATGGCATGCTCAAAGTCACAAAGCTGGCATGGGGCGGGGCTGGA
ACTCAAGAGTCAGACAGTCTGGCTCCAAGGCCTGGAGATCCCAGGCTGGGCCCCAGATTTAATTCAGCAAATATTGACTGACTGCTGTGG
ACAAAGTGCTGGGCTCACCTTGGAGGGATCCAACCTCCAGGAGCTCGAGCGCAGCAGGGTAGACAAGCCAGGGGCACGTGATGCGGCTGT
GGCAGAAGCCAAGTGCAGGAGCTCCCAGGCTCCTTTGTTTTACTGAGTCACCTTAAATGTAACTCTGCCCTCTCCCTTGCTTCGCCAAGG
CTAGCGAGAAACTCAGTCTTAGCCACACAGGAGGAATCGGACCCCTTCTGGGGGTTTATGTGGAGTCTGGGAAACCAAGGGTGGGGTGAG
GCCTGGTACTCAATCCAGGAGGGGCCCCTATGACCACCCTCGCCTGTTTTTCTTCTCAATGCTCCCTGATCACTGGACCACTGGACACTG
ATGTGTCCTCAGTGCTTGGGGTCTGGCTCTGCAGGCAGCCTGCAGCCAGCCTCCATCCCCCTTTCAGGGACAAATGGCCTTCCACCAGAG
TCGGTGAGTGGAGAGGCACAATGCCACTCCCCTTCCTGAGGTGGGGGTAGGGGAAGGGAGTCCCACAATGCAGTTACAAACAGGATGGAC
AAGAACACCTGCTCAGGAGTCAGACTTACAGGGTTCAAAGTTCTGCTCCAAGGTTTGACCCTAACAAGAATCACTTAGTAATAAGTGGTT

>82581_82581_2_SLC25A17-EPN3_SLC25A17_chr22_41215199_ENST00000435456_EPN3_chr17_48616548_ENST00000268933_length(amino acids)=424AA_BP=46
MSSGAPFLTPLAAASVGKVWLGLRGAAPMASVLSYESLVHAVAGAVEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQS
SILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDP
WALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGI
LGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGA

--------------------------------------------------------------
>82581_82581_3_SLC25A17-EPN3_SLC25A17_chr22_41215199_ENST00000542412_EPN3_chr17_48616245_ENST00000268933_length(transcript)=2904nt_BP=93nt
GTGGGAAAAGTGTGGCTGGGTCTTCGAGGAGCCGCACCAATGGCTTCCGTGCTGTCCTACGAAAGCCTGGTCCACGCCGTGGCCGGAGCC
GTGCCTGTCCCCCCAGCCTCCCACAGGGACGAGGACCTGCAGCTGCAGCTGGCTCTGCGCCTGAGCCGGCAGGAGCACGAGAAGGAGGTG
AGGTCCTGGCAGGGTGATGGCTCCCCCATGGCCAATGGTGCAGGGGCCGTGGTCCACCATCAGCGGGACAGAGAGCCTGAGAGAGAAGAG
AGAAAGGAGGAGGAGAAGCTAAAAACCAGCCAGTCCTCCATCCTGGACTTGGCTGACATCTTCGTACCTGCCCTGGCCCCGCCCTCCACA
CACTGCTCTGCTGACCCATGGGACATCCCAGGTTTTAGGCCGAACACAGAGGCCAGTGGATCCTCCTGGGGGCCTTCTGCAGACCCCTGG
TCTCCGATCCCCTCAGGAACCGTCCTGTCCCGAAGCCAGCCCTGGGATCTGACTCCCATGCTCTCCTCCTCTGAGCCCTGGGGCAGGACC
CCAGTGCTGCCTGCTGGGCCCCCCACCACAGACCCCTGGGCCCTGAACTCTCCCCACCACAAACTCCCCAGCACTGGGGCTGACCCTTGG
GGAGCCTCCCTGGAGACCTCCGACACACCTGGTGGTGCCTCGACCTTTGACCCATTTGCCAAACCTCCAGAATCCACAGAGACCAAGGAG
GGGCTGGAGCAGGCCCTGCCCTCTGGGAAGCCCAGCAGCCCTGTGGAGCTGGACCTGTTTGGAGACCCCAGCCCCAGTTCCAAGCAAAAT
GGCACGAAGGAGCCAGATGCCCTGGACCTGGGCATACTAGGGGAAGCACTAACCCAGCCAAGCAAAGAGGCCCGAGCTTGCCGGACTCCC
GAGTCCTTCCTGGGTCCCTCAGCTTCCTCCTTGGTCAACCTTGACTCGTTGGTCAAGGCACCCCAGGTTGCAAAGACCCGGAACCCCTTC
CTGACAGGTCTCAGCGCTCCGTCCCCCACCAACCCGTTCGGCGCGGGCGAGCCGGGCAGGCCGACGCTAAACCAGATGCGCACCGGCTCG
CCGGCGCTGGGCCTGGCAGGCGGGCCTGTGGGGGCGCCCCTGGGCTCCATGACCTACAGCGCCTCTCTGCCCCTCCCGCTCAGCAGCGTG
CCAGCTGGCTTGACCCTCCCCGCCTCGGTTAGCGTCTTCCCGCAGGCCGGAGCCTTCGCACCGCAGCCGCTGCTGCCCACGCCGAGCTCA
GCCGGGCCGCGGCCCCCGCCCCCGCAGACCGGCACCAACCCCTTCCTCTGAGCCCCGCCCCGTCCCATACCGGCCTGCGCCTGCGCCGGA
CGCTCCGCGGCCCCGCCTCCGGACCCGGGGCTGGGCGGGGCGCCGGTGCTAGTGGAACGCCGAGCCAGTGGCGGCTGGTATCCCGCGGCG
GCTCTGGAAGCTGGACGCGGACCACGGCCCGGGAGCTAGAAACTGAACGCCCGCATAATAAAGACTGGAACCCTCGTTCTCAGCTCTCAC
CAAGTGGACTTTTTGCGGGGTGTGGCGGCCGGGTCTCGACCACAGCGTGGATCACCGGCTGTTTAGGAAACTGCAGCTGCACAACGTGGG
GTGCAAAACTGCCCCGCTTCCTTTACAGCTCTTCTCAACCCTCACCTCCATCCCCCGTCACCCAGGCACCTTCGCTTCCAGATGCTGCCA
GGCTGTCACTCAATTCGGTCATTTCATTCATTTATCACACATGGGCACTGGGGTTGGGCTAACAGCAAGAGACAATAGGCCTTTGTTCCT
ATTTATTGGGTACTGCTTACGTGCTAAGCAGATCAGTTTATTTAATGCTTGCAACGACTCTCTGAGGTAGAAAATATTGTTAATTCCGTT
CAGGATCCCGGCTACATAATCTGTGGGGCTCAATACAAAATAAAAATGTAGGGGCTCCTTGTTCAAAATCGTATGAAGAATTTCAAAACA
GGGACAACAGAGCATGAAACCAAGCGCAAAGCCCACTGCAGTGCGATTGCACAGGTATCTCACCTTGCAGCCGGCACTACTCCCATTTTT
CAGGCAAGGAAACCGTGGCTCAGAGAGGTTGAATGGCATGCTCAAAGTCACAAAGCTGGCATGGGGCGGGGCTGGAACTCAAGAGTCAGA
CAGTCTGGCTCCAAGGCCTGGAGATCCCAGGCTGGGCCCCAGATTTAATTCAGCAAATATTGACTGACTGCTGTGGACAAAGTGCTGGGC
TCACCTTGGAGGGATCCAACCTCCAGGAGCTCGAGCGCAGCAGGGTAGACAAGCCAGGGGCACGTGATGCGGCTGTGGCAGAAGCCAAGT
GCAGGAGCTCCCAGGCTCCTTTGTTTTACTGAGTCACCTTAAATGTAACTCTGCCCTCTCCCTTGCTTCGCCAAGGCTAGCGAGAAACTC
AGTCTTAGCCACACAGGAGGAATCGGACCCCTTCTGGGGGTTTATGTGGAGTCTGGGAAACCAAGGGTGGGGTGAGGCCTGGTACTCAAT
CCAGGAGGGGCCCCTATGACCACCCTCGCCTGTTTTTCTTCTCAATGCTCCCTGATCACTGGACCACTGGACACTGATGTGTCCTCAGTG
CTTGGGGTCTGGCTCTGCAGGCAGCCTGCAGCCAGCCTCCATCCCCCTTTCAGGGACAAATGGCCTTCCACCAGAGTCGGTGAGTGGAGA
GGCACAATGCCACTCCCCTTCCTGAGGTGGGGGTAGGGGAAGGGAGTCCCACAATGCAGTTACAAACAGGATGGACAAGAACACCTGCTC
AGGAGTCAGACTTACAGGGTTCAAAGTTCTGCTCCAAGGTTTGACCCTAACAAGAATCACTTAGTAATAAGTGGTTATGCTCTGTGACCT

>82581_82581_3_SLC25A17-EPN3_SLC25A17_chr22_41215199_ENST00000542412_EPN3_chr17_48616245_ENST00000268933_length(amino acids)=431AA_BP=26
MGLRGAAPMASVLSYESLVHAVAGAVPVPPASHRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEE
KLKTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPA
GPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEP
DALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGL

--------------------------------------------------------------
>82581_82581_4_SLC25A17-EPN3_SLC25A17_chr22_41215199_ENST00000542412_EPN3_chr17_48616548_ENST00000268933_length(transcript)=2823nt_BP=93nt
GTGGGAAAAGTGTGGCTGGGTCTTCGAGGAGCCGCACCAATGGCTTCCGTGCTGTCCTACGAAAGCCTGGTCCACGCCGTGGCCGGAGCC
GTGGAGGTGAGGTCCTGGCAGGGTGATGGCTCCCCCATGGCCAATGGTGCAGGGGCCGTGGTCCACCATCAGCGGGACAGAGAGCCTGAG
AGAGAAGAGAGAAAGGAGGAGGAGAAGCTAAAAACCAGCCAGTCCTCCATCCTGGACTTGGCTGACATCTTCGTACCTGCCCTGGCCCCG
CCCTCCACACACTGCTCTGCTGACCCATGGGACATCCCAGGTTTTAGGCCGAACACAGAGGCCAGTGGATCCTCCTGGGGGCCTTCTGCA
GACCCCTGGTCTCCGATCCCCTCAGGAACCGTCCTGTCCCGAAGCCAGCCCTGGGATCTGACTCCCATGCTCTCCTCCTCTGAGCCCTGG
GGCAGGACCCCAGTGCTGCCTGCTGGGCCCCCCACCACAGACCCCTGGGCCCTGAACTCTCCCCACCACAAACTCCCCAGCACTGGGGCT
GACCCTTGGGGAGCCTCCCTGGAGACCTCCGACACACCTGGTGGTGCCTCGACCTTTGACCCATTTGCCAAACCTCCAGAATCCACAGAG
ACCAAGGAGGGGCTGGAGCAGGCCCTGCCCTCTGGGAAGCCCAGCAGCCCTGTGGAGCTGGACCTGTTTGGAGACCCCAGCCCCAGTTCC
AAGCAAAATGGCACGAAGGAGCCAGATGCCCTGGACCTGGGCATACTAGGGGAAGCACTAACCCAGCCAAGCAAAGAGGCCCGAGCTTGC
CGGACTCCCGAGTCCTTCCTGGGTCCCTCAGCTTCCTCCTTGGTCAACCTTGACTCGTTGGTCAAGGCACCCCAGGTTGCAAAGACCCGG
AACCCCTTCCTGACAGGTCTCAGCGCTCCGTCCCCCACCAACCCGTTCGGCGCGGGCGAGCCGGGCAGGCCGACGCTAAACCAGATGCGC
ACCGGCTCGCCGGCGCTGGGCCTGGCAGGCGGGCCTGTGGGGGCGCCCCTGGGCTCCATGACCTACAGCGCCTCTCTGCCCCTCCCGCTC
AGCAGCGTGCCAGCTGGCTTGACCCTCCCCGCCTCGGTTAGCGTCTTCCCGCAGGCCGGAGCCTTCGCACCGCAGCCGCTGCTGCCCACG
CCGAGCTCAGCCGGGCCGCGGCCCCCGCCCCCGCAGACCGGCACCAACCCCTTCCTCTGAGCCCCGCCCCGTCCCATACCGGCCTGCGCC
TGCGCCGGACGCTCCGCGGCCCCGCCTCCGGACCCGGGGCTGGGCGGGGCGCCGGTGCTAGTGGAACGCCGAGCCAGTGGCGGCTGGTAT
CCCGCGGCGGCTCTGGAAGCTGGACGCGGACCACGGCCCGGGAGCTAGAAACTGAACGCCCGCATAATAAAGACTGGAACCCTCGTTCTC
AGCTCTCACCAAGTGGACTTTTTGCGGGGTGTGGCGGCCGGGTCTCGACCACAGCGTGGATCACCGGCTGTTTAGGAAACTGCAGCTGCA
CAACGTGGGGTGCAAAACTGCCCCGCTTCCTTTACAGCTCTTCTCAACCCTCACCTCCATCCCCCGTCACCCAGGCACCTTCGCTTCCAG
ATGCTGCCAGGCTGTCACTCAATTCGGTCATTTCATTCATTTATCACACATGGGCACTGGGGTTGGGCTAACAGCAAGAGACAATAGGCC
TTTGTTCCTATTTATTGGGTACTGCTTACGTGCTAAGCAGATCAGTTTATTTAATGCTTGCAACGACTCTCTGAGGTAGAAAATATTGTT
AATTCCGTTCAGGATCCCGGCTACATAATCTGTGGGGCTCAATACAAAATAAAAATGTAGGGGCTCCTTGTTCAAAATCGTATGAAGAAT
TTCAAAACAGGGACAACAGAGCATGAAACCAAGCGCAAAGCCCACTGCAGTGCGATTGCACAGGTATCTCACCTTGCAGCCGGCACTACT
CCCATTTTTCAGGCAAGGAAACCGTGGCTCAGAGAGGTTGAATGGCATGCTCAAAGTCACAAAGCTGGCATGGGGCGGGGCTGGAACTCA
AGAGTCAGACAGTCTGGCTCCAAGGCCTGGAGATCCCAGGCTGGGCCCCAGATTTAATTCAGCAAATATTGACTGACTGCTGTGGACAAA
GTGCTGGGCTCACCTTGGAGGGATCCAACCTCCAGGAGCTCGAGCGCAGCAGGGTAGACAAGCCAGGGGCACGTGATGCGGCTGTGGCAG
AAGCCAAGTGCAGGAGCTCCCAGGCTCCTTTGTTTTACTGAGTCACCTTAAATGTAACTCTGCCCTCTCCCTTGCTTCGCCAAGGCTAGC
GAGAAACTCAGTCTTAGCCACACAGGAGGAATCGGACCCCTTCTGGGGGTTTATGTGGAGTCTGGGAAACCAAGGGTGGGGTGAGGCCTG
GTACTCAATCCAGGAGGGGCCCCTATGACCACCCTCGCCTGTTTTTCTTCTCAATGCTCCCTGATCACTGGACCACTGGACACTGATGTG
TCCTCAGTGCTTGGGGTCTGGCTCTGCAGGCAGCCTGCAGCCAGCCTCCATCCCCCTTTCAGGGACAAATGGCCTTCCACCAGAGTCGGT
GAGTGGAGAGGCACAATGCCACTCCCCTTCCTGAGGTGGGGGTAGGGGAAGGGAGTCCCACAATGCAGTTACAAACAGGATGGACAAGAA
CACCTGCTCAGGAGTCAGACTTACAGGGTTCAAAGTTCTGCTCCAAGGTTTGACCCTAACAAGAATCACTTAGTAATAAGTGGTTATGCT

>82581_82581_4_SLC25A17-EPN3_SLC25A17_chr22_41215199_ENST00000542412_EPN3_chr17_48616548_ENST00000268933_length(amino acids)=404AA_BP=26
MGLRGAAPMASVLSYESLVHAVAGAVEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSILDLADIFVPALAPPSTHC
SADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGA
SLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPES
FLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SLC25A17-EPN3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SLC25A17-EPN3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SLC25A17-EPN3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource