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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SLC25A25-WDR34 (FusionGDB2 ID:82622)

Fusion Gene Summary for SLC25A25-WDR34

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC25A25-WDR34
Fusion gene ID: 82622
HgeneTgene
Gene symbol

SLC25A25

WDR34

Gene ID

114789

89891

Gene namesolute carrier family 25 member 25WD repeat domain 34
SynonymsMCSC|PCSCL|SCAMC-2CFAP133|DIC5|FAP133|SRTD11|bA216B9.3
Cytomap

9q34.11

9q34.11

Type of geneprotein-codingprotein-coding
Descriptioncalcium-binding mitochondrial carrier protein SCaMC-2mitochondrial ATP-Mg/Pi carrier protein 3mitochondrial Ca(2+)-dependent solute carrier protein 3short calcium-binding mitochondrial carrier 2small calcium-binding mitochondrial carrier 2solute carrWD repeat-containing protein 34
Modification date2020031320200329
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000373064, ENST00000373066, 
ENST00000373068, ENST00000373069, 
ENST00000432073, ENST00000433501, 
ENST00000483181, ENST00000372715, 
Fusion gene scores* DoF score8 X 5 X 6=2407 X 4 X 6=168
# samples 88
** MAII scorelog2(8/240*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/168*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC25A25 [Title/Abstract] AND WDR34 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSLC25A25(130864760)-WDR34(131403218), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SLC25A25 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across WDR34 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-A4H2SLC25A25chr9

130864760

+WDR34chr9

131403218

-


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Fusion Gene ORF analysis for SLC25A25-WDR34

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000373064ENST00000483181SLC25A25chr9

130864760

+WDR34chr9

131403218

-
5CDS-intronENST00000373066ENST00000483181SLC25A25chr9

130864760

+WDR34chr9

131403218

-
5CDS-intronENST00000373068ENST00000483181SLC25A25chr9

130864760

+WDR34chr9

131403218

-
5CDS-intronENST00000373069ENST00000483181SLC25A25chr9

130864760

+WDR34chr9

131403218

-
5CDS-intronENST00000432073ENST00000483181SLC25A25chr9

130864760

+WDR34chr9

131403218

-
5CDS-intronENST00000433501ENST00000483181SLC25A25chr9

130864760

+WDR34chr9

131403218

-
In-frameENST00000373064ENST00000372715SLC25A25chr9

130864760

+WDR34chr9

131403218

-
In-frameENST00000373066ENST00000372715SLC25A25chr9

130864760

+WDR34chr9

131403218

-
In-frameENST00000373068ENST00000372715SLC25A25chr9

130864760

+WDR34chr9

131403218

-
In-frameENST00000373069ENST00000372715SLC25A25chr9

130864760

+WDR34chr9

131403218

-
In-frameENST00000432073ENST00000372715SLC25A25chr9

130864760

+WDR34chr9

131403218

-
In-frameENST00000433501ENST00000372715SLC25A25chr9

130864760

+WDR34chr9

131403218

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000373068SLC25A25chr9130864760+ENST00000372715WDR34chr9131403218-2215707292131700
ENST00000373069SLC25A25chr9130864760+ENST00000372715WDR34chr9131403218-2159651272075682
ENST00000432073SLC25A25chr9130864760+ENST00000372715WDR34chr9131403218-24619532512377708
ENST00000373066SLC25A25chr9130864760+ENST00000372715WDR34chr9131403218-24979892512413720
ENST00000373064SLC25A25chr9130864760+ENST00000372715WDR34chr9131403218-22577492632173636
ENST00000433501SLC25A25chr9130864760+ENST00000372715WDR34chr9131403218-20475392991963554

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000373068ENST00000372715SLC25A25chr9130864760+WDR34chr9131403218-0.0165323540.98346764
ENST00000373069ENST00000372715SLC25A25chr9130864760+WDR34chr9131403218-0.0118674730.98813254
ENST00000432073ENST00000372715SLC25A25chr9130864760+WDR34chr9131403218-0.0095133470.9904867
ENST00000373066ENST00000372715SLC25A25chr9130864760+WDR34chr9131403218-0.0094530720.99054694
ENST00000373064ENST00000372715SLC25A25chr9130864760+WDR34chr9131403218-0.0212294570.97877055
ENST00000433501ENST00000372715SLC25A25chr9130864760+WDR34chr9131403218-0.027270.97273004

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Fusion Genomic Features for SLC25A25-WDR34


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SLC25A25-WDR34


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:130864760/chr9:131403218)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+41060_71162470.0Calcium binding1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+51160_71194502.0Calcium binding1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+41060_71196504.0Calcium binding1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+51160_71208516.0Calcium binding1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+41060_71182490.0Calcium binding1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410114_149162470.0DomainEF-hand 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+41047_80162470.0DomainEF-hand 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+41078_113162470.0DomainEF-hand 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511114_149194502.0DomainEF-hand 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+51147_80194502.0DomainEF-hand 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+51178_113194502.0DomainEF-hand 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410114_149196504.0DomainEF-hand 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+41047_80196504.0DomainEF-hand 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+41078_113196504.0DomainEF-hand 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511114_149208516.0DomainEF-hand 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+51147_80208516.0DomainEF-hand 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+51178_113208516.0DomainEF-hand 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410114_149182490.0DomainEF-hand 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+41047_80182490.0DomainEF-hand 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+41078_113182490.0DomainEF-hand 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+5111_189194502.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+4101_189196504.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+5111_189208516.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511190_207208516.0TransmembraneHelical%3B Name%3D1
TgeneWDR34chr9:130864760chr9:131403218ENST0000037271509106_13162537.0RegionDYNLRB1 binding
TgeneWDR34chr9:130864760chr9:131403218ENST000003727150980_9362537.0RegionDYNLL2 binding
TgeneWDR34chr9:130864760chr9:131403218ENST0000037271509215_25562537.0RepeatWD 1
TgeneWDR34chr9:130864760chr9:131403218ENST0000037271509264_30862537.0RepeatWD 2
TgeneWDR34chr9:130864760chr9:131403218ENST0000037271509390_43062537.0RepeatWD 3
TgeneWDR34chr9:130864760chr9:131403218ENST0000037271509433_47362537.0RepeatWD 4
TgeneWDR34chr9:130864760chr9:131403218ENST0000037271509480_52062537.0RepeatWD 5

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+41060_7159367.0Calcium binding1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410114_14959367.0DomainEF-hand 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+41047_8059367.0DomainEF-hand 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+41078_11359367.0DomainEF-hand 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410184_270162470.0RepeatNote=Solcar 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410278_363162470.0RepeatNote=Solcar 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410375_463162470.0RepeatNote=Solcar 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511184_270194502.0RepeatNote=Solcar 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511278_363194502.0RepeatNote=Solcar 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511375_463194502.0RepeatNote=Solcar 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410184_270196504.0RepeatNote=Solcar 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410278_363196504.0RepeatNote=Solcar 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410375_463196504.0RepeatNote=Solcar 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511184_270208516.0RepeatNote=Solcar 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511278_363208516.0RepeatNote=Solcar 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511375_463208516.0RepeatNote=Solcar 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410184_270182490.0RepeatNote=Solcar 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410278_363182490.0RepeatNote=Solcar 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410375_463182490.0RepeatNote=Solcar 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410184_27059367.0RepeatNote=Solcar 1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410278_36359367.0RepeatNote=Solcar 2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410375_46359367.0RepeatNote=Solcar 3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+4101_189162470.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410208_244162470.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410265_287162470.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410302_337162470.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410358_380162470.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410399_437162470.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410458_469162470.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511208_244194502.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511265_287194502.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511302_337194502.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511358_380194502.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511399_437194502.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511458_469194502.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410208_244196504.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410265_287196504.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410302_337196504.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410358_380196504.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410399_437196504.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410458_469196504.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511208_244208516.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511265_287208516.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511302_337208516.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511358_380208516.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511399_437208516.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511458_469208516.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+4101_189182490.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410208_244182490.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410265_287182490.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410302_337182490.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410358_380182490.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410399_437182490.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410458_469182490.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+4101_18959367.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410208_24459367.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410265_28759367.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410302_33759367.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410358_38059367.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410399_43759367.0Topological domainMitochondrial matrix
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410458_46959367.0Topological domainMitochondrial intermembrane
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410190_207162470.0TransmembraneHelical%3B Name%3D1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410245_264162470.0TransmembraneHelical%3B Name%3D2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410288_301162470.0TransmembraneHelical%3B Name%3D3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410338_357162470.0TransmembraneHelical%3B Name%3D4
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410381_398162470.0TransmembraneHelical%3B Name%3D5
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373064+410438_457162470.0TransmembraneHelical%3B Name%3D6
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511190_207194502.0TransmembraneHelical%3B Name%3D1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511245_264194502.0TransmembraneHelical%3B Name%3D2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511288_301194502.0TransmembraneHelical%3B Name%3D3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511338_357194502.0TransmembraneHelical%3B Name%3D4
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511381_398194502.0TransmembraneHelical%3B Name%3D5
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373066+511438_457194502.0TransmembraneHelical%3B Name%3D6
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410190_207196504.0TransmembraneHelical%3B Name%3D1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410245_264196504.0TransmembraneHelical%3B Name%3D2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410288_301196504.0TransmembraneHelical%3B Name%3D3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410338_357196504.0TransmembraneHelical%3B Name%3D4
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410381_398196504.0TransmembraneHelical%3B Name%3D5
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373068+410438_457196504.0TransmembraneHelical%3B Name%3D6
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511245_264208516.0TransmembraneHelical%3B Name%3D2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511288_301208516.0TransmembraneHelical%3B Name%3D3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511338_357208516.0TransmembraneHelical%3B Name%3D4
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511381_398208516.0TransmembraneHelical%3B Name%3D5
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000373069+511438_457208516.0TransmembraneHelical%3B Name%3D6
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410190_207182490.0TransmembraneHelical%3B Name%3D1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410245_264182490.0TransmembraneHelical%3B Name%3D2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410288_301182490.0TransmembraneHelical%3B Name%3D3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410338_357182490.0TransmembraneHelical%3B Name%3D4
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410381_398182490.0TransmembraneHelical%3B Name%3D5
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000432073+410438_457182490.0TransmembraneHelical%3B Name%3D6
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410190_20759367.0TransmembraneHelical%3B Name%3D1
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410245_26459367.0TransmembraneHelical%3B Name%3D2
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410288_30159367.0TransmembraneHelical%3B Name%3D3
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410338_35759367.0TransmembraneHelical%3B Name%3D4
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410381_39859367.0TransmembraneHelical%3B Name%3D5
HgeneSLC25A25chr9:130864760chr9:131403218ENST00000433501+410438_45759367.0TransmembraneHelical%3B Name%3D6


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Fusion Gene Sequence for SLC25A25-WDR34


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>82622_82622_1_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000373064_WDR34_chr9_131403218_ENST00000372715_length(transcript)=2257nt_BP=749nt
CGGTGACGTCAGCCCTGATCTTTGTGCCTCTCACTTGAGCAACCTGATGCCACCTTCTCCCCCGGGCTCTGTGTTCATTGGCTGTTGGCA
GGACTTGCCGTGGGAGGGCTTTTTTCTTTTTTCAATTAAGTAAAAGGGCAGGGCTTAAGCAGCCAATGACAGCTGAGGCCAGGCTTGTCT
TATGCAAGTTTCCCGGGACCGGCAGCATTTAGGGAACTTGCTCCCGGTGGTGAGGGCAGTGGAGCACCCAGCAGGCCGCCAACATGCTCT
GTCTGTGCCTGTATGTGCCGGTCATCGGGGAAGCCCAGACCGAGTTCCAGTACTTTGAGTCGAAGGGGCTCCCTGCCGAGCTGAAGTCCA
TTTTCAAGCTCAGTGTCTTCATCCCCTCCCAGGAATTCTCCACCTACCGCCAGTGGAAGCAGAAAATTGTACAAGCTGGAGATAAGGACC
TTGATGGGCAGCTAGACTTTGAAGAATTTGTCCATTATCTCCAAGATCATGAGAAGAAGCTGAGGCTGGTGTTTAAGAGTTTGGACAAAA
AGAATGATGGACGCATTGACGCGCAGGAGATCATGCAGTCCCTGCGGGACTTGGGAGTCAAGATATCTGAACAGCAGGCAGAAAAAATTC
TCAAGAGCATGGATAAAAACGGCACGATGACCATTGACTGGAACGAGTGGAGAGACTACCACCTCCTCCACCCCGTGGAAAACATCCCCG
AGATCATCCTCTACTGGAAGCATTCCACGAAAAGTTGCCAGACGGCCAGCATTGCCACTGCCAGTGCATCCGCCCAGGCCAGGAATCATG
TGGACGCCCAGGTGCAGACGGAGGCCCCCGTGCCTGTCAGCGTGCAGCCCCCGTCCCAGTATGACATACCCAGGCTCGCAGCCTTTCTTC
GGAGAGTGGAGGCCATGGTCATCCGAGAGCTGAACAAGAATTGGCAGAGCCACGCGTTTGATGGCTTCGAGGTGAACTGGACCGAGCAGC
AGCAGATGGTGTCTTGTCTGTATACCCTGGGCTACCCGCCAGCCCAAGCGCAGGGTCTGCATGTGACCAGCATCTCCTGGAACTCCACTG
GCTCTGTGGTGGCCTGTGCCTACGGCCGGCTGGACCATGGGGACTGGAGCACGCTTAAGTCCTTCGTGTGTGCCTGGAACCTGGACCGGC
GAGACCTGCGTCCCCAGCAGCCGTCGGCCGTGGTGGAGGTCCCCAGCGCTGTCCTGTGTCTGGCCTTCCACCCCACGCAGCCCTCCCACG
TCGCAGGAGGGCTGTACAGTGGTGAGGTGTTGGTGTGGGACCTGAGCCGTCTTGAGGACCCGCTGCTGTGGCGCACAGGCCTGACGGATG
ACACCCACACAGACCCTGTGTCCCAGGTGGTGTGGCTGCCCGAGCCTGGGCACAGCCACCGCTTCCAGGTGCTGAGTGTGGCCACCGACG
GGAAGGTGCTACTCTGGCAGGGCATCGGGGTAGGCCAGCTGCAGCTCACAGAGGGCTTCGCCCTGGTCATGCAGCAGCTGCCACGGAGCA
CCAAGCTCAAGAAGCATCCCCGCGGGGAGACCGAGGTGGGCGCCACGGCAGTGGCCTTCTCCAGCTTTGACCCTAGGCTGTTCATTCTGG
GCACGGAAGGCGGCTTCCCGCTCAAGTGTTCCCTGGCAGCTGGAGAGGCAGCCCTCACGCGGATGCCCAGCTCCGTGCCCCTGCGGGCCC
CAGCACAGTTTACCTTCTCCCCCCACGGCGGTCCCATCTACTCTGTGAGCTGTTCCCCCTTCCACAGGAATCTCTTCCTGAGCGCTGGGA
CTGACGGGCATGTCCACCTGTACTCCATGCTGCAGGCCCCTCCCTTGACTTCGCTGCAGCTCTCCCTCAAGTATCTGTTTGCTGTGCGCT
GGTCCCCAGTGCGGCCCTTGGTTTTTGCAGCTGCCTCTGGGAAAGGTGACGTGCAGCTGTTTGATCTCCAGAAAAGCTCCCAGAAACCCA
CAGTTTTGATCAAGCAAACCCAGGATGAAAGCCCTGTCTACTGTCTGGAGTTCAACAGCCAGCAGACTCAGCTCTTGGCTGCGGGCGATG
CCCAGGGCACAGTGAAGGTGTGGCAGCTGAGCACAGAGTTCACGGAACAAGGGCCCCGGGAAGCTGAGGACCTGGACTGCCTGGCAGCAG
AGGTGGCGGCCTGAGGGGTCCCGGGAGGCGGGTGCAAGCCTTCGCTGTGCCGAGCCTTGTGTTTCTGACGCAAGCCAAATGAAGAAAAGC

>82622_82622_1_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000373064_WDR34_chr9_131403218_ENST00000372715_length(amino acids)=636AA_BP=162
MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSL
DKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTKSCQTASIATASASAQAR
NHVDAQVQTEAPVPVSVQPPSQYDIPRLAAFLRRVEAMVIRELNKNWQSHAFDGFEVNWTEQQQMVSCLYTLGYPPAQAQGLHVTSISWN
STGSVVACAYGRLDHGDWSTLKSFVCAWNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWRTGL
TDDTHTDPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQQLPRSTKLKKHPRGETEVGATAVAFSSFDPRLF
ILGTEGGFPLKCSLAAGEAALTRMPSSVPLRAPAQFTFSPHGGPIYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLTSLQLSLKYLFA
VRWSPVRPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQDESPVYCLEFNSQQTQLLAAGDAQGTVKVWQLSTEFTEQGPREAEDLDCL

--------------------------------------------------------------
>82622_82622_2_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000373066_WDR34_chr9_131403218_ENST00000372715_length(transcript)=2497nt_BP=989nt
GCGAGGACAGCTGAATAACTGGGAGCTCGAAGTTGCTTGCTGCCTCCGGGAGTGGTCTGCTTGGCTGTCGCGTTTTCCTTTTCTTTTTTT
TTTTTTTTAAAAAAAAGCCAAACGTTTGCTCACCATCACCTGCAGAAGTGAGTTTTTATTGAAGAAGCTCCAGCTGCTTTCTCCTTATTG
CCGGCAGCCTGGCAAGCCTCCCTTAGAGTGAGCTACTTCTCAGGCCGGGCACGACAGCAGTGCTAGCACATTTGAAAAAGCAGGAAACCG
CCCCTGCATGCAGAGCTTCCAGCCTGAGAACCCCAGGCCCGTCCTCCCAGCAGCTGTGTAGCCAGAGAGCGTTGGTACTGTGGTCACATC
CCTCAAAAGTGAACAGTCGCCATCAGAGGCGTTTGGAGGAGACCGTGATGTTGCAGATGCTGTGGCATTTCCTAGCTAGCTTTTTCCCCA
GGGCTGGGTGCCACGGCTCCAGAGAGGGGGACGATCGTGAAGTCAGAGGCACCCCAGCCCCTGCCTGGAGAGACCAGATGGCAAGCTTTT
TGGGGAAACAGGACGGAAGGGCTGAGGCCACGGAAAAAAGACCCACCATTTTGCTGGTGGTTGGACCTGCAGAGCAGTTTCCTAAGAAAA
TTGTACAAGCTGGAGATAAGGACCTTGATGGGCAGCTAGACTTTGAAGAATTTGTCCATTATCTCCAAGATCATGAGAAGAAGCTGAGGC
TGGTGTTTAAGAGTTTGGACAAAAAGAATGATGGACGCATTGACGCGCAGGAGATCATGCAGTCCCTGCGGGACTTGGGAGTCAAGATAT
CTGAACAGCAGGCAGAAAAAATTCTCAAGAGAATACGAACGGGCCATTTCTGGGGCCCTGTCACCTACATGGATAAAAACGGCACGATGA
CCATTGACTGGAACGAGTGGAGAGACTACCACCTCCTCCACCCCGTGGAAAACATCCCCGAGATCATCCTCTACTGGAAGCATTCCACGA
AAAGTTGCCAGACGGCCAGCATTGCCACTGCCAGTGCATCCGCCCAGGCCAGGAATCATGTGGACGCCCAGGTGCAGACGGAGGCCCCCG
TGCCTGTCAGCGTGCAGCCCCCGTCCCAGTATGACATACCCAGGCTCGCAGCCTTTCTTCGGAGAGTGGAGGCCATGGTCATCCGAGAGC
TGAACAAGAATTGGCAGAGCCACGCGTTTGATGGCTTCGAGGTGAACTGGACCGAGCAGCAGCAGATGGTGTCTTGTCTGTATACCCTGG
GCTACCCGCCAGCCCAAGCGCAGGGTCTGCATGTGACCAGCATCTCCTGGAACTCCACTGGCTCTGTGGTGGCCTGTGCCTACGGCCGGC
TGGACCATGGGGACTGGAGCACGCTTAAGTCCTTCGTGTGTGCCTGGAACCTGGACCGGCGAGACCTGCGTCCCCAGCAGCCGTCGGCCG
TGGTGGAGGTCCCCAGCGCTGTCCTGTGTCTGGCCTTCCACCCCACGCAGCCCTCCCACGTCGCAGGAGGGCTGTACAGTGGTGAGGTGT
TGGTGTGGGACCTGAGCCGTCTTGAGGACCCGCTGCTGTGGCGCACAGGCCTGACGGATGACACCCACACAGACCCTGTGTCCCAGGTGG
TGTGGCTGCCCGAGCCTGGGCACAGCCACCGCTTCCAGGTGCTGAGTGTGGCCACCGACGGGAAGGTGCTACTCTGGCAGGGCATCGGGG
TAGGCCAGCTGCAGCTCACAGAGGGCTTCGCCCTGGTCATGCAGCAGCTGCCACGGAGCACCAAGCTCAAGAAGCATCCCCGCGGGGAGA
CCGAGGTGGGCGCCACGGCAGTGGCCTTCTCCAGCTTTGACCCTAGGCTGTTCATTCTGGGCACGGAAGGCGGCTTCCCGCTCAAGTGTT
CCCTGGCAGCTGGAGAGGCAGCCCTCACGCGGATGCCCAGCTCCGTGCCCCTGCGGGCCCCAGCACAGTTTACCTTCTCCCCCCACGGCG
GTCCCATCTACTCTGTGAGCTGTTCCCCCTTCCACAGGAATCTCTTCCTGAGCGCTGGGACTGACGGGCATGTCCACCTGTACTCCATGC
TGCAGGCCCCTCCCTTGACTTCGCTGCAGCTCTCCCTCAAGTATCTGTTTGCTGTGCGCTGGTCCCCAGTGCGGCCCTTGGTTTTTGCAG
CTGCCTCTGGGAAAGGTGACGTGCAGCTGTTTGATCTCCAGAAAAGCTCCCAGAAACCCACAGTTTTGATCAAGCAAACCCAGGATGAAA
GCCCTGTCTACTGTCTGGAGTTCAACAGCCAGCAGACTCAGCTCTTGGCTGCGGGCGATGCCCAGGGCACAGTGAAGGTGTGGCAGCTGA
GCACAGAGTTCACGGAACAAGGGCCCCGGGAAGCTGAGGACCTGGACTGCCTGGCAGCAGAGGTGGCGGCCTGAGGGGTCCCGGGAGGCG

>82622_82622_2_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000373066_WDR34_chr9_131403218_ENST00000372715_length(amino acids)=720AA_BP=246
MKKQETAPACRASSLRTPGPSSQQLCSQRALVLWSHPSKVNSRHQRRLEETVMLQMLWHFLASFFPRAGCHGSREGDDREVRGTPAPAWR
DQMASFLGKQDGRAEATEKRPTILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLR
DLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTKSCQTASIATASASAQARNHVDAQ
VQTEAPVPVSVQPPSQYDIPRLAAFLRRVEAMVIRELNKNWQSHAFDGFEVNWTEQQQMVSCLYTLGYPPAQAQGLHVTSISWNSTGSVV
ACAYGRLDHGDWSTLKSFVCAWNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWRTGLTDDTHT
DPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQQLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEG
GFPLKCSLAAGEAALTRMPSSVPLRAPAQFTFSPHGGPIYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLTSLQLSLKYLFAVRWSPV
RPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQDESPVYCLEFNSQQTQLLAAGDAQGTVKVWQLSTEFTEQGPREAEDLDCLAAEVAA

--------------------------------------------------------------
>82622_82622_3_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000373068_WDR34_chr9_131403218_ENST00000372715_length(transcript)=2215nt_BP=707nt
TGCCGGCGTCTCCGAGCCCGCGCTCCCAGCTGCAGAGCGCCTGGCTTGCCTCCCGCGCGGTCACCGCCGGCCCGCCGCCCCCGCTCCCGC
CCGCGCCCGGAGCCCCTGCCTCGCGCCCGATGGTGAGCAGTGTGTTGTGCCGCTGTGTGGCCTCCCCGCCGCCGGACGCCGCCGCCACCG
CCGCCTCTTCGTCTGCCTCATCGCCGGCGTCCGTGGGGGACCCCTGCGGCGGCGCTATCTGCGGGGGCCCGGACCACCGGCTGCGCCTGT
GGAGACTCTTTCAGACGCTCGACGTCAACCGGGACGGCGGCCTGTGTGTCAACGACCTGGCGGTGGGGCTGCGGCGCCTGGGACTGCACC
GCACCGAGGGCGAGCTCCAGAAAATTGTACAAGCTGGAGATAAGGACCTTGATGGGCAGCTAGACTTTGAAGAATTTGTCCATTATCTCC
AAGATCATGAGAAGAAGCTGAGGCTGGTGTTTAAGAGTTTGGACAAAAAGAATGATGGACGCATTGACGCGCAGGAGATCATGCAGTCCC
TGCGGGACTTGGGAGTCAAGATATCTGAACAGCAGGCAGAAAAAATTCTCAAGAGCATGGATAAAAACGGCACGATGACCATTGACTGGA
ACGAGTGGAGAGACTACCACCTCCTCCACCCCGTGGAAAACATCCCCGAGATCATCCTCTACTGGAAGCATTCCACGAAAAGTTGCCAGA
CGGCCAGCATTGCCACTGCCAGTGCATCCGCCCAGGCCAGGAATCATGTGGACGCCCAGGTGCAGACGGAGGCCCCCGTGCCTGTCAGCG
TGCAGCCCCCGTCCCAGTATGACATACCCAGGCTCGCAGCCTTTCTTCGGAGAGTGGAGGCCATGGTCATCCGAGAGCTGAACAAGAATT
GGCAGAGCCACGCGTTTGATGGCTTCGAGGTGAACTGGACCGAGCAGCAGCAGATGGTGTCTTGTCTGTATACCCTGGGCTACCCGCCAG
CCCAAGCGCAGGGTCTGCATGTGACCAGCATCTCCTGGAACTCCACTGGCTCTGTGGTGGCCTGTGCCTACGGCCGGCTGGACCATGGGG
ACTGGAGCACGCTTAAGTCCTTCGTGTGTGCCTGGAACCTGGACCGGCGAGACCTGCGTCCCCAGCAGCCGTCGGCCGTGGTGGAGGTCC
CCAGCGCTGTCCTGTGTCTGGCCTTCCACCCCACGCAGCCCTCCCACGTCGCAGGAGGGCTGTACAGTGGTGAGGTGTTGGTGTGGGACC
TGAGCCGTCTTGAGGACCCGCTGCTGTGGCGCACAGGCCTGACGGATGACACCCACACAGACCCTGTGTCCCAGGTGGTGTGGCTGCCCG
AGCCTGGGCACAGCCACCGCTTCCAGGTGCTGAGTGTGGCCACCGACGGGAAGGTGCTACTCTGGCAGGGCATCGGGGTAGGCCAGCTGC
AGCTCACAGAGGGCTTCGCCCTGGTCATGCAGCAGCTGCCACGGAGCACCAAGCTCAAGAAGCATCCCCGCGGGGAGACCGAGGTGGGCG
CCACGGCAGTGGCCTTCTCCAGCTTTGACCCTAGGCTGTTCATTCTGGGCACGGAAGGCGGCTTCCCGCTCAAGTGTTCCCTGGCAGCTG
GAGAGGCAGCCCTCACGCGGATGCCCAGCTCCGTGCCCCTGCGGGCCCCAGCACAGTTTACCTTCTCCCCCCACGGCGGTCCCATCTACT
CTGTGAGCTGTTCCCCCTTCCACAGGAATCTCTTCCTGAGCGCTGGGACTGACGGGCATGTCCACCTGTACTCCATGCTGCAGGCCCCTC
CCTTGACTTCGCTGCAGCTCTCCCTCAAGTATCTGTTTGCTGTGCGCTGGTCCCCAGTGCGGCCCTTGGTTTTTGCAGCTGCCTCTGGGA
AAGGTGACGTGCAGCTGTTTGATCTCCAGAAAAGCTCCCAGAAACCCACAGTTTTGATCAAGCAAACCCAGGATGAAAGCCCTGTCTACT
GTCTGGAGTTCAACAGCCAGCAGACTCAGCTCTTGGCTGCGGGCGATGCCCAGGGCACAGTGAAGGTGTGGCAGCTGAGCACAGAGTTCA
CGGAACAAGGGCCCCGGGAAGCTGAGGACCTGGACTGCCTGGCAGCAGAGGTGGCGGCCTGAGGGGTCCCGGGAGGCGGGTGCAAGCCTT

>82622_82622_3_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000373068_WDR34_chr9_131403218_ENST00000372715_length(amino acids)=700AA_BP=11
MQSAWLASRAVTAGPPPPLPPAPGAPASRPMVSSVLCRCVASPPPDAAATAASSSASSPASVGDPCGGAICGGPDHRLRLWRLFQTLDVN
RDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISE
QQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTKSCQTASIATASASAQARNHVDAQVQTEAPVPVSVQPPSQYDIP
RLAAFLRRVEAMVIRELNKNWQSHAFDGFEVNWTEQQQMVSCLYTLGYPPAQAQGLHVTSISWNSTGSVVACAYGRLDHGDWSTLKSFVC
AWNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWRTGLTDDTHTDPVSQVVWLPEPGHSHRFQV
LSVATDGKVLLWQGIGVGQLQLTEGFALVMQQLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEGGFPLKCSLAAGEAALTRMPS
SVPLRAPAQFTFSPHGGPIYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLTSLQLSLKYLFAVRWSPVRPLVFAAASGKGDVQLFDLQ

--------------------------------------------------------------
>82622_82622_4_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000373069_WDR34_chr9_131403218_ENST00000372715_length(transcript)=2159nt_BP=651nt
GCGCCCGGAGCCCCTGCCTCGCGCCCGATGGTGAGCAGTGTGTTGTGCCGCTGTGTGGCCTCCCCGCCGCCGGACGCCGCCGCCACCGCC
GCCTCTTCGTCTGCCTCATCGCCGGCGTCCGTGGGGGACCCCTGCGGCGGCGCTATCTGCGGGGGCCCGGACCACCGGCTGCGCCTGTGG
AGACTCTTTCAGACGCTCGACGTCAACCGGGACGGCGGCCTGTGTGTCAACGACCTGGCGGTGGGGCTGCGGCGCCTGGGACTGCACCGC
ACCGAGGGCGAGCTCCAGAAAATTGTACAAGCTGGAGATAAGGACCTTGATGGGCAGCTAGACTTTGAAGAATTTGTCCATTATCTCCAA
GATCATGAGAAGAAGCTGAGGCTGGTGTTTAAGAGTTTGGACAAAAAGAATGATGGACGCATTGACGCGCAGGAGATCATGCAGTCCCTG
CGGGACTTGGGAGTCAAGATATCTGAACAGCAGGCAGAAAAAATTCTCAAGAGAATACGAACGGGCCATTTCTGGGGCCCTGTCACCTAC
ATGGATAAAAACGGCACGATGACCATTGACTGGAACGAGTGGAGAGACTACCACCTCCTCCACCCCGTGGAAAACATCCCCGAGATCATC
CTCTACTGGAAGCATTCCACGAAAAGTTGCCAGACGGCCAGCATTGCCACTGCCAGTGCATCCGCCCAGGCCAGGAATCATGTGGACGCC
CAGGTGCAGACGGAGGCCCCCGTGCCTGTCAGCGTGCAGCCCCCGTCCCAGTATGACATACCCAGGCTCGCAGCCTTTCTTCGGAGAGTG
GAGGCCATGGTCATCCGAGAGCTGAACAAGAATTGGCAGAGCCACGCGTTTGATGGCTTCGAGGTGAACTGGACCGAGCAGCAGCAGATG
GTGTCTTGTCTGTATACCCTGGGCTACCCGCCAGCCCAAGCGCAGGGTCTGCATGTGACCAGCATCTCCTGGAACTCCACTGGCTCTGTG
GTGGCCTGTGCCTACGGCCGGCTGGACCATGGGGACTGGAGCACGCTTAAGTCCTTCGTGTGTGCCTGGAACCTGGACCGGCGAGACCTG
CGTCCCCAGCAGCCGTCGGCCGTGGTGGAGGTCCCCAGCGCTGTCCTGTGTCTGGCCTTCCACCCCACGCAGCCCTCCCACGTCGCAGGA
GGGCTGTACAGTGGTGAGGTGTTGGTGTGGGACCTGAGCCGTCTTGAGGACCCGCTGCTGTGGCGCACAGGCCTGACGGATGACACCCAC
ACAGACCCTGTGTCCCAGGTGGTGTGGCTGCCCGAGCCTGGGCACAGCCACCGCTTCCAGGTGCTGAGTGTGGCCACCGACGGGAAGGTG
CTACTCTGGCAGGGCATCGGGGTAGGCCAGCTGCAGCTCACAGAGGGCTTCGCCCTGGTCATGCAGCAGCTGCCACGGAGCACCAAGCTC
AAGAAGCATCCCCGCGGGGAGACCGAGGTGGGCGCCACGGCAGTGGCCTTCTCCAGCTTTGACCCTAGGCTGTTCATTCTGGGCACGGAA
GGCGGCTTCCCGCTCAAGTGTTCCCTGGCAGCTGGAGAGGCAGCCCTCACGCGGATGCCCAGCTCCGTGCCCCTGCGGGCCCCAGCACAG
TTTACCTTCTCCCCCCACGGCGGTCCCATCTACTCTGTGAGCTGTTCCCCCTTCCACAGGAATCTCTTCCTGAGCGCTGGGACTGACGGG
CATGTCCACCTGTACTCCATGCTGCAGGCCCCTCCCTTGACTTCGCTGCAGCTCTCCCTCAAGTATCTGTTTGCTGTGCGCTGGTCCCCA
GTGCGGCCCTTGGTTTTTGCAGCTGCCTCTGGGAAAGGTGACGTGCAGCTGTTTGATCTCCAGAAAAGCTCCCAGAAACCCACAGTTTTG
ATCAAGCAAACCCAGGATGAAAGCCCTGTCTACTGTCTGGAGTTCAACAGCCAGCAGACTCAGCTCTTGGCTGCGGGCGATGCCCAGGGC
ACAGTGAAGGTGTGGCAGCTGAGCACAGAGTTCACGGAACAAGGGCCCCGGGAAGCTGAGGACCTGGACTGCCTGGCAGCAGAGGTGGCG

>82622_82622_4_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000373069_WDR34_chr9_131403218_ENST00000372715_length(amino acids)=682AA_BP=208
MVSSVLCRCVASPPPDAAATAASSSASSPASVGDPCGGAICGGPDHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIV
QAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTI
DWNEWRDYHLLHPVENIPEIILYWKHSTKSCQTASIATASASAQARNHVDAQVQTEAPVPVSVQPPSQYDIPRLAAFLRRVEAMVIRELN
KNWQSHAFDGFEVNWTEQQQMVSCLYTLGYPPAQAQGLHVTSISWNSTGSVVACAYGRLDHGDWSTLKSFVCAWNLDRRDLRPQQPSAVV
EVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWRTGLTDDTHTDPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQGIGVG
QLQLTEGFALVMQQLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEGGFPLKCSLAAGEAALTRMPSSVPLRAPAQFTFSPHGGP
IYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLTSLQLSLKYLFAVRWSPVRPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQDESP

--------------------------------------------------------------
>82622_82622_5_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000432073_WDR34_chr9_131403218_ENST00000372715_length(transcript)=2461nt_BP=953nt
GCGAGGACAGCTGAATAACTGGGAGCTCGAAGTTGCTTGCTGCCTCCGGGAGTGGTCTGCTTGGCTGTCGCGTTTTCCTTTTCTTTTTTT
TTTTTTTTAAAAAAAAGCCAAACGTTTGCTCACCATCACCTGCAGAAGTGAGTTTTTATTGAAGAAGCTCCAGCTGCTTTCTCCTTATTG
CCGGCAGCCTGGCAAGCCTCCCTTAGAGTGAGCTACTTCTCAGGCCGGGCACGACAGCAGTGCTAGCACATTTGAAAAAGCAGGAAACCG
CCCCTGCATGCAGAGCTTCCAGCCTGAGAACCCCAGGCCCGTCCTCCCAGCAGCTGTGTAGCCAGAGAGCGTTGGTACTGTGGTCACATC
CCTCAAAAGTGAACAGTCGCCATCAGAGGCGTTTGGAGGAGACCGTGATGTTGCAGATGCTGTGGCATTTCCTAGCTAGCTTTTTCCCCA
GGGCTGGGTGCCACGGCTCCAGAGAGGGGGACGATCGTGAAGTCAGAGGCACCCCAGCCCCTGCCTGGAGAGACCAGATGGCAAGCTTTT
TGGGGAAACAGGACGGAAGGGCTGAGGCCACGGAAAAAAGACCCACCATTTTGCTGGTGGTTGGACCTGCAGAGCAGTTTCCTAAGAAAA
TTGTACAAGCTGGAGATAAGGACCTTGATGGGCAGCTAGACTTTGAAGAATTTGTCCATTATCTCCAAGATCATGAGAAGAAGCTGAGGC
TGGTGTTTAAGAGTTTGGACAAAAAGAATGATGGACGCATTGACGCGCAGGAGATCATGCAGTCCCTGCGGGACTTGGGAGTCAAGATAT
CTGAACAGCAGGCAGAAAAAATTCTCAAGAGCATGGATAAAAACGGCACGATGACCATTGACTGGAACGAGTGGAGAGACTACCACCTCC
TCCACCCCGTGGAAAACATCCCCGAGATCATCCTCTACTGGAAGCATTCCACGAAAAGTTGCCAGACGGCCAGCATTGCCACTGCCAGTG
CATCCGCCCAGGCCAGGAATCATGTGGACGCCCAGGTGCAGACGGAGGCCCCCGTGCCTGTCAGCGTGCAGCCCCCGTCCCAGTATGACA
TACCCAGGCTCGCAGCCTTTCTTCGGAGAGTGGAGGCCATGGTCATCCGAGAGCTGAACAAGAATTGGCAGAGCCACGCGTTTGATGGCT
TCGAGGTGAACTGGACCGAGCAGCAGCAGATGGTGTCTTGTCTGTATACCCTGGGCTACCCGCCAGCCCAAGCGCAGGGTCTGCATGTGA
CCAGCATCTCCTGGAACTCCACTGGCTCTGTGGTGGCCTGTGCCTACGGCCGGCTGGACCATGGGGACTGGAGCACGCTTAAGTCCTTCG
TGTGTGCCTGGAACCTGGACCGGCGAGACCTGCGTCCCCAGCAGCCGTCGGCCGTGGTGGAGGTCCCCAGCGCTGTCCTGTGTCTGGCCT
TCCACCCCACGCAGCCCTCCCACGTCGCAGGAGGGCTGTACAGTGGTGAGGTGTTGGTGTGGGACCTGAGCCGTCTTGAGGACCCGCTGC
TGTGGCGCACAGGCCTGACGGATGACACCCACACAGACCCTGTGTCCCAGGTGGTGTGGCTGCCCGAGCCTGGGCACAGCCACCGCTTCC
AGGTGCTGAGTGTGGCCACCGACGGGAAGGTGCTACTCTGGCAGGGCATCGGGGTAGGCCAGCTGCAGCTCACAGAGGGCTTCGCCCTGG
TCATGCAGCAGCTGCCACGGAGCACCAAGCTCAAGAAGCATCCCCGCGGGGAGACCGAGGTGGGCGCCACGGCAGTGGCCTTCTCCAGCT
TTGACCCTAGGCTGTTCATTCTGGGCACGGAAGGCGGCTTCCCGCTCAAGTGTTCCCTGGCAGCTGGAGAGGCAGCCCTCACGCGGATGC
CCAGCTCCGTGCCCCTGCGGGCCCCAGCACAGTTTACCTTCTCCCCCCACGGCGGTCCCATCTACTCTGTGAGCTGTTCCCCCTTCCACA
GGAATCTCTTCCTGAGCGCTGGGACTGACGGGCATGTCCACCTGTACTCCATGCTGCAGGCCCCTCCCTTGACTTCGCTGCAGCTCTCCC
TCAAGTATCTGTTTGCTGTGCGCTGGTCCCCAGTGCGGCCCTTGGTTTTTGCAGCTGCCTCTGGGAAAGGTGACGTGCAGCTGTTTGATC
TCCAGAAAAGCTCCCAGAAACCCACAGTTTTGATCAAGCAAACCCAGGATGAAAGCCCTGTCTACTGTCTGGAGTTCAACAGCCAGCAGA
CTCAGCTCTTGGCTGCGGGCGATGCCCAGGGCACAGTGAAGGTGTGGCAGCTGAGCACAGAGTTCACGGAACAAGGGCCCCGGGAAGCTG
AGGACCTGGACTGCCTGGCAGCAGAGGTGGCGGCCTGAGGGGTCCCGGGAGGCGGGTGCAAGCCTTCGCTGTGCCGAGCCTTGTGTTTCT

>82622_82622_5_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000432073_WDR34_chr9_131403218_ENST00000372715_length(amino acids)=708AA_BP=234
MKKQETAPACRASSLRTPGPSSQQLCSQRALVLWSHPSKVNSRHQRRLEETVMLQMLWHFLASFFPRAGCHGSREGDDREVRGTPAPAWR
DQMASFLGKQDGRAEATEKRPTILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLR
DLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTKSCQTASIATASASAQARNHVDAQVQTEAPVPVSVQ
PPSQYDIPRLAAFLRRVEAMVIRELNKNWQSHAFDGFEVNWTEQQQMVSCLYTLGYPPAQAQGLHVTSISWNSTGSVVACAYGRLDHGDW
STLKSFVCAWNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWRTGLTDDTHTDPVSQVVWLPEP
GHSHRFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQQLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEGGFPLKCSLAAGE
AALTRMPSSVPLRAPAQFTFSPHGGPIYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLTSLQLSLKYLFAVRWSPVRPLVFAAASGKG

--------------------------------------------------------------
>82622_82622_6_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000433501_WDR34_chr9_131403218_ENST00000372715_length(transcript)=2047nt_BP=539nt
GGCCGCCAACATGCTCTGTCTGTGCCTGTATGTGCCGGTCATCGGGGAAGCCCAGACCGAGTTCCAGTACTTTGAGTCGAAGGGGCTCCC
TGCCGAGCTGAAGTCCATTTTCAAGCTCAGTGTCTTCATCCCCTCCCAGGAATTCTCCACCTACCGCCAGTGGAAGCAGGTCTGTGGGGT
GACCGCGCGGAAGGGAGAGGCGCATTCAACCGAAAATTGTACAAGCTGGAGATAAGGACCTTGATGGGCAGCTAGACTTTGAAGAATTTG
TCCATTATCTCCAAGATCATGAGAAGAAGCTGAGGCTGGTGTTTAAGAGTTTGGACAAAAAGAATGATGGACGCATTGACGCGCAGGAGA
TCATGCAGTCCCTGCGGGACTTGGGAGTCAAGATATCTGAACAGCAGGCAGAAAAAATTCTCAAGAGCATGGATAAAAACGGCACGATGA
CCATTGACTGGAACGAGTGGAGAGACTACCACCTCCTCCACCCCGTGGAAAACATCCCCGAGATCATCCTCTACTGGAAGCATTCCACGA
AAAGTTGCCAGACGGCCAGCATTGCCACTGCCAGTGCATCCGCCCAGGCCAGGAATCATGTGGACGCCCAGGTGCAGACGGAGGCCCCCG
TGCCTGTCAGCGTGCAGCCCCCGTCCCAGTATGACATACCCAGGCTCGCAGCCTTTCTTCGGAGAGTGGAGGCCATGGTCATCCGAGAGC
TGAACAAGAATTGGCAGAGCCACGCGTTTGATGGCTTCGAGGTGAACTGGACCGAGCAGCAGCAGATGGTGTCTTGTCTGTATACCCTGG
GCTACCCGCCAGCCCAAGCGCAGGGTCTGCATGTGACCAGCATCTCCTGGAACTCCACTGGCTCTGTGGTGGCCTGTGCCTACGGCCGGC
TGGACCATGGGGACTGGAGCACGCTTAAGTCCTTCGTGTGTGCCTGGAACCTGGACCGGCGAGACCTGCGTCCCCAGCAGCCGTCGGCCG
TGGTGGAGGTCCCCAGCGCTGTCCTGTGTCTGGCCTTCCACCCCACGCAGCCCTCCCACGTCGCAGGAGGGCTGTACAGTGGTGAGGTGT
TGGTGTGGGACCTGAGCCGTCTTGAGGACCCGCTGCTGTGGCGCACAGGCCTGACGGATGACACCCACACAGACCCTGTGTCCCAGGTGG
TGTGGCTGCCCGAGCCTGGGCACAGCCACCGCTTCCAGGTGCTGAGTGTGGCCACCGACGGGAAGGTGCTACTCTGGCAGGGCATCGGGG
TAGGCCAGCTGCAGCTCACAGAGGGCTTCGCCCTGGTCATGCAGCAGCTGCCACGGAGCACCAAGCTCAAGAAGCATCCCCGCGGGGAGA
CCGAGGTGGGCGCCACGGCAGTGGCCTTCTCCAGCTTTGACCCTAGGCTGTTCATTCTGGGCACGGAAGGCGGCTTCCCGCTCAAGTGTT
CCCTGGCAGCTGGAGAGGCAGCCCTCACGCGGATGCCCAGCTCCGTGCCCCTGCGGGCCCCAGCACAGTTTACCTTCTCCCCCCACGGCG
GTCCCATCTACTCTGTGAGCTGTTCCCCCTTCCACAGGAATCTCTTCCTGAGCGCTGGGACTGACGGGCATGTCCACCTGTACTCCATGC
TGCAGGCCCCTCCCTTGACTTCGCTGCAGCTCTCCCTCAAGTATCTGTTTGCTGTGCGCTGGTCCCCAGTGCGGCCCTTGGTTTTTGCAG
CTGCCTCTGGGAAAGGTGACGTGCAGCTGTTTGATCTCCAGAAAAGCTCCCAGAAACCCACAGTTTTGATCAAGCAAACCCAGGATGAAA
GCCCTGTCTACTGTCTGGAGTTCAACAGCCAGCAGACTCAGCTCTTGGCTGCGGGCGATGCCCAGGGCACAGTGAAGGTGTGGCAGCTGA
GCACAGAGTTCACGGAACAAGGGCCCCGGGAAGCTGAGGACCTGGACTGCCTGGCAGCAGAGGTGGCGGCCTGAGGGGTCCCGGGAGGCG

>82622_82622_6_SLC25A25-WDR34_SLC25A25_chr9_130864760_ENST00000433501_WDR34_chr9_131403218_ENST00000372715_length(amino acids)=554AA_BP=80
MRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTKSCQTASIAT
ASASAQARNHVDAQVQTEAPVPVSVQPPSQYDIPRLAAFLRRVEAMVIRELNKNWQSHAFDGFEVNWTEQQQMVSCLYTLGYPPAQAQGL
HVTSISWNSTGSVVACAYGRLDHGDWSTLKSFVCAWNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLED
PLLWRTGLTDDTHTDPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQQLPRSTKLKKHPRGETEVGATAVAF
SSFDPRLFILGTEGGFPLKCSLAAGEAALTRMPSSVPLRAPAQFTFSPHGGPIYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLTSLQ
LSLKYLFAVRWSPVRPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQDESPVYCLEFNSQQTQLLAAGDAQGTVKVWQLSTEFTEQGPR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SLC25A25-WDR34


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SLC25A25-WDR34


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SLC25A25-WDR34


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource