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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SLC25A26-ARIH2 (FusionGDB2 ID:82623)

Fusion Gene Summary for SLC25A26-ARIH2

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC25A26-ARIH2
Fusion gene ID: 82623
HgeneTgene
Gene symbol

SLC25A26

ARIH2

Gene ID

115286

10425

Gene namesolute carrier family 25 member 26ariadne RBR E3 ubiquitin protein ligase 2
SynonymsCOXPD28|SAMCARI2|TRIAD1
Cytomap

3p14.1

3p21.31

Type of geneprotein-codingprotein-coding
DescriptionS-adenosylmethionine mitochondrial carrier proteinmitochondrial S-adenosylmethionine transportersolute carrier family 25 (S-adenosylmethionine carrier), member 26solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 26E3 ubiquitin-protein ligase ARIH2RING-type E3 ubiquitin transferase ARIH2all-trans retinoic acid inducible RING fingerariadne homolog 2protein ariadne-2 homolog
Modification date2020032620200313
UniProtAcc.

O95376

Ensembl transtripts involved in fusion geneENST00000484768, ENST00000536651, 
ENST00000336733, ENST00000354883, 
ENST00000413054, 		ENST00000356401, 
ENST00000449376, ENST00000490095, 
Fusion gene scores* DoF score11 X 8 X 6=52817 X 18 X 8=2448
# samples 1121
** MAII scorelog2(11/528*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(21/2448*10)=-3.54314232502653
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC25A26 [Title/Abstract] AND ARIH2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSLC25A26(66313803)-ARIH2(48999044), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneARIH2

GO:0000209

protein polyubiquitination

16118314|19340006

TgeneARIH2

GO:0006511

ubiquitin-dependent protein catabolic process

16118314

TgeneARIH2

GO:0016567

protein ubiquitination

24076655

TgeneARIH2

GO:0048588

developmental cell growth

19340006

TgeneARIH2

GO:0070534

protein K63-linked ubiquitination

19340006

TgeneARIH2

GO:0070936

protein K48-linked ubiquitination

16118314|19340006

TgeneARIH2

GO:0071425

hematopoietic stem cell proliferation

16118314|19340006


check buttonFusion gene breakpoints across SLC25A26 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARIH2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A0EASLC25A26chr3

66313803

+ARIH2chr3

48999044

+


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Fusion Gene ORF analysis for SLC25A26-ARIH2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000484768ENST00000356401SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
3UTR-3CDSENST00000484768ENST00000449376SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
3UTR-3CDSENST00000536651ENST00000356401SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
3UTR-3CDSENST00000536651ENST00000449376SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
3UTR-3UTRENST00000484768ENST00000490095SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
3UTR-3UTRENST00000536651ENST00000490095SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
5CDS-3UTRENST00000336733ENST00000490095SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
5CDS-3UTRENST00000354883ENST00000490095SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
5CDS-3UTRENST00000413054ENST00000490095SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
In-frameENST00000336733ENST00000356401SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
In-frameENST00000336733ENST00000449376SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
In-frameENST00000354883ENST00000356401SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
In-frameENST00000354883ENST00000449376SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
In-frameENST00000413054ENST00000356401SLC25A26chr3

66313803

+ARIH2chr3

48999044

+
In-frameENST00000413054ENST00000449376SLC25A26chr3

66313803

+ARIH2chr3

48999044

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000354883SLC25A26chr366313803+ENST00000356401ARIH2chr348999044+552011817282407559
ENST00000354883SLC25A26chr366313803+ENST00000449376ARIH2chr348999044+275811817282407559
ENST00000336733SLC25A26chr366313803+ENST00000356401ARIH2chr348999044+4718379731605510
ENST00000336733SLC25A26chr366313803+ENST00000449376ARIH2chr348999044+1956379731605510
ENST00000413054SLC25A26chr366313803+ENST00000356401ARIH2chr348999044+4602263411489482
ENST00000413054SLC25A26chr366313803+ENST00000449376ARIH2chr348999044+1840263411489482

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000354883ENST00000356401SLC25A26chr366313803+ARIH2chr348999044+0.0012966660.99870336
ENST00000354883ENST00000449376SLC25A26chr366313803+ARIH2chr348999044+0.0020950980.9979049
ENST00000336733ENST00000356401SLC25A26chr366313803+ARIH2chr348999044+0.0003592330.9996407
ENST00000336733ENST00000449376SLC25A26chr366313803+ARIH2chr348999044+0.0005664610.99943346
ENST00000413054ENST00000356401SLC25A26chr366313803+ARIH2chr348999044+0.0003556530.9996444
ENST00000413054ENST00000449376SLC25A26chr366313803+ARIH2chr348999044+0.0006505960.9993494

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Fusion Genomic Features for SLC25A26-ARIH2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SLC25A26chr366313803+ARIH2chr348999044+7.06E-060.99999297
SLC25A26chr366313803+ARIH2chr348999044+7.06E-060.99999297

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SLC25A26-ARIH2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:66313803/chr3:48999044)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ARIH2

O95376

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3 (PubMed:16118314, PubMed:17646546, PubMed:19340006, PubMed:24076655). Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-5-RING ubiquitin ligase complex (ECS complex, also named CRL5 complex) and initiating ubiquitination of ECS substrates: associates with ECS complex and specifically mediates addition of the first ubiquitin on ECS targets (By similarity). The initial ubiquitin is then elongated (By similarity). E3 ubiquitin-protein ligase activity is activated upon binding to neddylated form of the ECS complex (PubMed:24076655). Mediates 'Lys-6', 'Lys-48'- and 'Lys-63'-linked polyubiquitination (PubMed:16118314, PubMed:17646546, PubMed:19340006). May play a role in myelopoiesis (PubMed:19340006). {ECO:0000250|UniProtKB:Q9Y4X5, ECO:0000269|PubMed:16118314, ECO:0000269|PubMed:17646546, ECO:0000269|PubMed:19340006, ECO:0000269|PubMed:24076655}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A26chr3:66313803chr3:48999044ENST00000336733+495_2563187.0TransmembraneHelical%3B Name%3D1
TgeneARIH2chr3:66313803chr3:48999044ENST00000356401216135_34485494.0RegionTRIAD supradomain
TgeneARIH2chr3:66313803chr3:48999044ENST00000356401216359_49385494.0RegionAriadne domain
TgeneARIH2chr3:66313803chr3:48999044ENST00000449376317135_34485494.0RegionTRIAD supradomain
TgeneARIH2chr3:66313803chr3:48999044ENST00000449376317359_49385494.0RegionAriadne domain
TgeneARIH2chr3:66313803chr3:48999044ENST00000356401216139_18885494.0Zinc fingerRING-type 1
TgeneARIH2chr3:66313803chr3:48999044ENST00000356401216208_27085494.0Zinc fingerIBR-type
TgeneARIH2chr3:66313803chr3:48999044ENST00000356401216297_32685494.0Zinc fingerRING-type 2%3B atypical
TgeneARIH2chr3:66313803chr3:48999044ENST00000449376317139_18885494.0Zinc fingerRING-type 1
TgeneARIH2chr3:66313803chr3:48999044ENST00000449376317208_27085494.0Zinc fingerIBR-type
TgeneARIH2chr3:66313803chr3:48999044ENST00000449376317297_32685494.0Zinc fingerRING-type 2%3B atypical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A26chr3:66313803chr3:48999044ENST00000336733+49177_26563187.0RepeatNote=Solcar 3
HgeneSLC25A26chr3:66313803chr3:48999044ENST00000336733+494_7763187.0RepeatNote=Solcar 1
HgeneSLC25A26chr3:66313803chr3:48999044ENST00000336733+4986_16863187.0RepeatNote=Solcar 2
HgeneSLC25A26chr3:66313803chr3:48999044ENST00000336733+49142_16263187.0TransmembraneHelical%3B Name%3D4
HgeneSLC25A26chr3:66313803chr3:48999044ENST00000336733+49182_20263187.0TransmembraneHelical%3B Name%3D5
HgeneSLC25A26chr3:66313803chr3:48999044ENST00000336733+49238_25863187.0TransmembraneHelical%3B Name%3D6
HgeneSLC25A26chr3:66313803chr3:48999044ENST00000336733+4949_6963187.0TransmembraneHelical%3B Name%3D2
HgeneSLC25A26chr3:66313803chr3:48999044ENST00000336733+4985_10563187.0TransmembraneHelical%3B Name%3D3
TgeneARIH2chr3:66313803chr3:48999044ENST0000035640121665_11285494.0RegionUBA-like
TgeneARIH2chr3:66313803chr3:48999044ENST0000044937631765_11285494.0RegionUBA-like


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Fusion Gene Sequence for SLC25A26-ARIH2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>82623_82623_1_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000336733_ARIH2_chr3_48999044_ENST00000356401_length(transcript)=4718nt_BP=379nt
AAACATGGCGGCGCCCAGCGCGCGAGGACGTGATCCGCTTCTGCTCCGGCTTGGATTGTAGCCTTGACGAGGTCTGAGCGACCATGGACC
GGCCGGGGTTCGTGGCAGCGCTGGTGCTGCTGCATTTTTTATCACCTATGAATATGTGAAGTGGTTTTTGCATGCTGATTCATCTTCATA
TTTGACACCTATGAAACATATGTTGGCTGCCTCTGCTGGAGAAGTGGTTGCCTGCCTGATTCGAGTTCCATCTGAAGTGGTTAAGCAGAG
GGCACAGGTATCTGCTTCTACAAGAACATTTCAGATTTTCTCTAACATCTTATATGAAGAGGGTATCCAAGGGTTGTATCGAGGCTATAA
AAGCACAGTTTTAAGAGAGGTATCTCATTCAGTTGCTAAACTTATATTAGTTAATTTCCACTGGCAAGTTTCAGAGATATTGGACAGATA
CAAGTCCAATTCTGCTCAACTGCTTGTTGAGGCTCGAGTTCAGCCTAATCCATCAAAACATGTTCCCACATCCCATCCCCCTCACCACTG
TGCAGTGTGTATGCAGTTTGTGCGAAAGGAAAACCTACTCTCTCTGGCCTGTCAGCACCAGTTTTGCCGCAGCTGCTGGGAGCAGCACTG
CTCAGTTCTCGTCAAGGACGGCGTGGGCGTGGGAGTCTCTTGCATGGCTCAGGACTGTCCACTCCGTACACCAGAGGACTTTGTGTTTCC
ATTGCTTCCCAATGAAGAATTGAGAGAGAAATACAGGCGCTACCTCTTCAGGGACTATGTGGAGAGTCATTACCAGCTCCAGCTGTGCCC
TGGTGCAGACTGCCCCATGGTTATTCGGGTACAGGAGCCTAGAGCTCGCCGAGTACAGTGCAATCGGTGCAACGAGGTCTTCTGTTTCAA
GTGTCGTCAGATGTATCACGCACCCACAGACTGTGCCACAATCCGGAAATGGCTCACGAAGTGTGCAGACGACTCTGAAACAGCCAACTA
CATTAGTGCTCACACTAAAGACTGTCCCAAGTGCAACATCTGCATTGAGAAGAATGGAGGCTGCAATCACATGCAATGCTCCAAATGTAA
ACACGACTTCTGCTGGATGTGTCTAGGAGATTGGAAGACTCATGGCAGTGAATACTATGAGTGCAGTCGTTACAAGGAGAATCCTGACAT
CGTGAACCAGAGCCAACAAGCCCAGGCGAGGGAAGCCCTCAAGAAGTACTTATTCTACTTTGAGAGGTGGGAAAACCACAATAAAAGCTT
GCAGCTAGAGGCACAGACATACCAGCGGATTCACGAGAAGATTCAGGAGAGGGTCATGAACAATCTGGGGACATGGATCGACTGGCAGTA
CCTACAGAATGCTGCCAAGCTCTTGGCCAAGTGTCGATACACCCTGCAATACACCTACCCATATGCATATTACATGGAGTCCGGACCCAG
GAAGAAGCTGTTTGAATACCAGCAGGCTCAGCTGGAGGCTGAGATCGAAAACCTCTCATGGAAAGTGGAGCGTGCAGACAGCTATGACAG
AGGGGACTTGGAGAACCAGATGCATATAGCGGAGCAGCGGAGGAGAACCCTGCTGAAAGATTTCCATGACACCTAAGTTGGGATGTGGAT
GTGCCGGGGTGAGGAAGATGTGGCTGCAAGGTCTCCCGGCTGCCATACTGCATGCTGCAGGCTCTGCCTTTCATGACCCCAGGCAACAGC
CAGGGCCCCACTCCTGAGAGACACTGGCAACACCTCTTAGTTGATTTCTGTTTTCTTCTCTTTTCACTTTTTGTTTCTACCAGGGTAGAG
GCCATGTTGAACTGGCCTCTTTTCAGGACTTTTATTTCCCCCTGGATGGTTGTTGGGAGGGAGGGAAAGTGTTTTCTGAATGGCTATTAA
TAGTATTAGATCATTACAACTTATGTAACTTTCAAAGGTTGTACAATTATACAAAAAAAAAAAAAAGGCAAACTATAGGATAACACAGAG
CCCTTTTTGAAAATAAATTGGCATTGGAGTGTTTTACCCTCTAGCTGTTTTACTTAGAATGTAACATATGCTGCCTACCCACCTCAAAAT
GTCTGTACTGCAAGAGGGCCCTGGGCCTCTGCTTTCCATATTCACGTTTGGCCAGAGTTGTAGTCCCAAAGAAGAGCATGGGTGGCAGAT
GGTAGGGAATTGAACTGGCCTGTGCAATGGGCATGGAGCACAAGGGGTCACAGCATGCCTCCTGCCTTACCGTGGCAGTACGGAGACAGT
CCAGAACATGGTCTTCTTGCCACGGGGTGTTGTTGTCTCTGGTGGTGCTGCATGTCTGTGGCTCACCTTTATTCTTGAAACTGAGGTTTA
CCTGGATCTGGCTACTGAGGCTAGAGCCCACAGCAGAATGGGGTTGGGCCTGTGGCCCCCCAAACTAGGGGGTGTGGGTTCATCACAGTG
TTGCCTTTTGTCTCCTAAAGATAGGGATCTACTTTTGAAGGGAATTGTTCCTCCCAAATAAATTTGCTTTACCTTGGTCCTTTCTTTTGT
GCCAGTATTCAAGTGGTATAGCTCTGAGCAGGGTCACATTTGGCCAAACCTGACACTGTCTTGCTGCATTCTCCTTTGGCAAACATCAGG
GTCAGAATTCAGGATAGCCCTTCCTAGGGCACTGGACTTTCTGGCATGGGGGCTGTGTTTGCACAAGTTATTTTCATGTTACCTGGAGAG
TGTCCAGAGGCTGCTCTGAGGCTGAGGTGTGTTCCCCCTTGCCTGGTTCCAGCTGTCAGAGGGATACCATCCTAGGGTCTGGGAATCCAA
GGCCACGAGACTCCTTGGTTTGTGGTCCGAGATCCTGTACTAAGGAGGGTCTGGCCAGAGGAACAGACCAGCTTTTGCACAATGAAGCGC
AAGGGAACAAGTGGTTTGCCTGGTGTCCTACCTGTCCTGAACCTGGTCCTGTGGGCCATTGAAAAGTTAGATCTGTGATCTCTGGGGTTT
TTGTGGCTTTGTTCAATGCTTCCACTCTAGGGCAGGCAGAGCAGTCTATACTCTCCCAAGCCTGCTTGACCTCCAAGTAGAGCTGATACA
GAGATCTGTGAATATTGTGATAGAAATTCTTTGGTATTCATACATTTCAGCTGCAAGTCAGCAATTTCCCAGGTACCATGTAAGCTATAA
AACAGTCATTCTTAAAGACAGAGGATAGCTGTGACTCATGGGATCATGAGGTCCATGGCTGGTTGCAGGTTCCCTTTTTCCTTCCTCAGG
TTTTGTCTCTTCCTGTGTTGTCCCCAGCAAGGGAGAGACTGTGGGGTGGATTGGGAGAACAGATTAGGAGTATAGCAAATGAACCCAGAA
TGGAACAGTGGGGAGCTAACTGTGAATGAGGAGAGTACCTGCTGCAGGACCTGGAGGTCAGGTGTGAATGCTGTATTGGCACAGGGAATA
AATATCCTGGCGTCTGGAGCCTTCACCTCTCCGTCAAGTCCTTCCTGTGATACTGCCATGGCACAGGATCTGAGTTGCAGCTCTGCACCC
TAAATCACACCCTGGGCATTGTCTGGGCTGCAGGGCTGCCAGGTTCTGTACTTGTGTCCAGCTGTGGCCCTGGATGCTGGAGCTGGAGGG
TTTTCTGTGCTCAGACTGTAGCCTGTAGCTCTTGGCCTGTGTAGAGCCCCCTCCTGTGCCCTCAGTGGCTGTCGTTTGTTAACATCATCA
GGAAGATGGGAAAGGTCAGGCAGAATTTTTCTGCCCTACAAAGGGTGGAAGAGAAAGGACACAGTATTTTCATGAATTTACCATATATCT
TTGTTTTTCTTCAACGAAAAAGTTAATTGAGGCAATGTCATCTGCTCAAAGTTGAGTGGTTTATTCACAATAAACTGTAAGTTTCTGATT
ATAAAAATGTGTCTAGAGTCTTTCTTCATGGGGTCTAGGTAGTCTTCTGAGCCCACAGGGGTCTGGCCAGTGAACACCAGAGGAGTGCCT
TCCTATCAGTCAGCCCCTTCTTCCAGAGGGCTGTGGAGGCCCCAGTGGCCAAACTCGGCTCTGTTTTCCCTTTCTGGCTGTTGGGGGAGA
GGGCACCTGTAAGTGATCCCTGTGGAATGAAGTAGAAAATCCTGCCAGTTTTCCGCTCTCCTCTCCCTCAGTACAGGCTGAATCATTCCC
CACCACAGATAGATCCCAGGGTTGTGGTAGAGTACTGATATAAATGTCCCAACCCCCCCATTCTGAGACCTCCGGACCCCTCCAAAGCAG
ACATGGGAATGTAGGGCTGTGGAATATGGCAGGGTGAACTCCAGCTTCACGGGAGCCCTAAGGGTTATGAAGAGACAACTTGGGGCAGAA
ACAAGTGTGGAGTCTAATCTCAAGGGTGAAGGACAGGAAATGAGGTTTGGATTGATTAAGGGGGTCCACATTTGTGGTGTCAGAAGTGGC
AGTAGTGTCAGTGATAAGTAGCTCAGGGGTAGAGTGGAGGCTCCATAGCTGTGGGCAACATGCACAGGGCACCTGTGGCTAGAAGAGGCC
TCATACATTGCCAGTCTGAACTCCGCAGCTCTTCCTCTGGACCTCAGGTGTGCCAAGCCCCACGCTTGGCACCTGGGCATACAGTGGTAT
GCAAGTGATTCACGTGCTCTAGCTTCCAGGAGCTTCCAATCCATGGGGAACATAGAAGGAATTGATCACTAGTGAATGTTTGTTTTTTGT

>82623_82623_1_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000336733_ARIH2_chr3_48999044_ENST00000356401_length(amino acids)=510AA_BP=102
MSDHGPAGVRGSAGAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQG
LYRGYKSTVLREVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRS
CWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCN
EVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRY
KENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYY

--------------------------------------------------------------
>82623_82623_2_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000336733_ARIH2_chr3_48999044_ENST00000449376_length(transcript)=1956nt_BP=379nt
AAACATGGCGGCGCCCAGCGCGCGAGGACGTGATCCGCTTCTGCTCCGGCTTGGATTGTAGCCTTGACGAGGTCTGAGCGACCATGGACC
GGCCGGGGTTCGTGGCAGCGCTGGTGCTGCTGCATTTTTTATCACCTATGAATATGTGAAGTGGTTTTTGCATGCTGATTCATCTTCATA
TTTGACACCTATGAAACATATGTTGGCTGCCTCTGCTGGAGAAGTGGTTGCCTGCCTGATTCGAGTTCCATCTGAAGTGGTTAAGCAGAG
GGCACAGGTATCTGCTTCTACAAGAACATTTCAGATTTTCTCTAACATCTTATATGAAGAGGGTATCCAAGGGTTGTATCGAGGCTATAA
AAGCACAGTTTTAAGAGAGGTATCTCATTCAGTTGCTAAACTTATATTAGTTAATTTCCACTGGCAAGTTTCAGAGATATTGGACAGATA
CAAGTCCAATTCTGCTCAACTGCTTGTTGAGGCTCGAGTTCAGCCTAATCCATCAAAACATGTTCCCACATCCCATCCCCCTCACCACTG
TGCAGTGTGTATGCAGTTTGTGCGAAAGGAAAACCTACTCTCTCTGGCCTGTCAGCACCAGTTTTGCCGCAGCTGCTGGGAGCAGCACTG
CTCAGTTCTCGTCAAGGACGGCGTGGGCGTGGGAGTCTCTTGCATGGCTCAGGACTGTCCACTCCGTACACCAGAGGACTTTGTGTTTCC
ATTGCTTCCCAATGAAGAATTGAGAGAGAAATACAGGCGCTACCTCTTCAGGGACTATGTGGAGAGTCATTACCAGCTCCAGCTGTGCCC
TGGTGCAGACTGCCCCATGGTTATTCGGGTACAGGAGCCTAGAGCTCGCCGAGTACAGTGCAATCGGTGCAACGAGGTCTTCTGTTTCAA
GTGTCGTCAGATGTATCACGCACCCACAGACTGTGCCACAATCCGGAAATGGCTCACGAAGTGTGCAGACGACTCTGAAACAGCCAACTA
CATTAGTGCTCACACTAAAGACTGTCCCAAGTGCAACATCTGCATTGAGAAGAATGGAGGCTGCAATCACATGCAATGCTCCAAATGTAA
ACACGACTTCTGCTGGATGTGTCTAGGAGATTGGAAGACTCATGGCAGTGAATACTATGAGTGCAGTCGTTACAAGGAGAATCCTGACAT
CGTGAACCAGAGCCAACAAGCCCAGGCGAGGGAAGCCCTCAAGAAGTACTTATTCTACTTTGAGAGGTGGGAAAACCACAATAAAAGCTT
GCAGCTAGAGGCACAGACATACCAGCGGATTCACGAGAAGATTCAGGAGAGGGTCATGAACAATCTGGGGACATGGATCGACTGGCAGTA
CCTACAGAATGCTGCCAAGCTCTTGGCCAAGTGTCGATACACCCTGCAATACACCTACCCATATGCATATTACATGGAGTCCGGACCCAG
GAAGAAGCTGTTTGAATACCAGCAGGCTCAGCTGGAGGCTGAGATCGAAAACCTCTCATGGAAAGTGGAGCGTGCAGACAGCTATGACAG
AGGGGACTTGGAGAACCAGATGCATATAGCGGAGCAGCGGAGGAGAACCCTGCTGAAAGATTTCCATGACACCTAAGTTGGGATGTGGAT
GTGCCGGGGTGAGGAAGATGTGGCTGCAAGGTCTCCCGGCTGCCATACTGCATGCTGCAGGCTCTGCCTTTCATGACCCCAGGCAACAGC
CAGGGCCCCACTCCTGAGAGACACTGGCAACACCTCTTAGTTGATTTCTGTTTTCTTCTCTTTTCACTTTTTGTTTCTACCAGGGTAGAG
GCCATGTTGAACTGGCCTCTTTTCAGGACTTTTATTTCCCCCTGGATGGTTGTTGGGAGGGAGGGAAAGTGTTTTCTGAATGGCTATTAA

>82623_82623_2_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000336733_ARIH2_chr3_48999044_ENST00000449376_length(amino acids)=510AA_BP=102
MSDHGPAGVRGSAGAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQG
LYRGYKSTVLREVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRS
CWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCN
EVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRY
KENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYY

--------------------------------------------------------------
>82623_82623_3_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000354883_ARIH2_chr3_48999044_ENST00000356401_length(transcript)=5520nt_BP=1181nt
AACCTGAAGCTCTCAGAGCTTCCCTGTCTTCATCTATCAGCCCAGGGAGAGGAATCAGTGGTTTTCCAAAAGCTGTACCTCTTTCCATAA
ATACAAGGATGAAGGGCTGAGATGATGGCAGTTAGAATTATATTGAGAAATGGTAGCGGGATCTGAGAAAGCAAGGCCATGAGTTGAAAG
CAGAGAGAAGGCGGTTCGAGTGGAGCCCTGATGAAGTTCATGCTCATGGTTGCCCAGCCATTAACACGGGCTCATCACATCTGTTTCCAG
ATTGCTTCTAGAACTTAGCTACCCTCGTTCTATAAGATGGAATGAAAATGCGTACTACATACAGATCATGAAAAGACGCAAAGAAAATGC
ATCTTCACATTGCAGTTCAGAATCACGCCGGCCTCATTCTACCGCTGCTCTCTCCTGGATCTCGGCCACGGATCTTTTGCTCGCGAAAGT
TCCTCCGTCTAGCTGCACACAACGCTGCTGCAGGAAACCGAGGTAAGGGATTTGCCGAGACTTAGCTCCACCACACTCCCCGAGGCCCCG
CCCCTCCTCTCTGGCCCTCCCCTAGGCCCAGGTGTCTCGCGTTGCACGTGCAGTTGTTGTGGTTCTACGTCACGTGGTCCCGGAAGTTCA
AGACAGACCCGCCTCAAACATGGCGGCGCCCAGCGCGCGAGGACGTGATCCGCTTCTGCTCCGGCTTGGATTGTAGCCTTGACGAGGTCT
GAGCGACCATGGACCGGCCGGGGTTCGTGGCAGCGCTGGTGGCTGGTGGGGTAGCAGGTGTTTCTGTTGACTTGATATTATTTCCTCTGG
ATACCATTAAAACCAGGCTGCAGAGTCCCCAAGGATTTAGTAAGGCTGGTGGTTTTCATGGAATATATGCTGGCGTTCCTTCTGCTGCTA
TTGGATCCTTTCCTAATGCTGCTGCATTTTTTATCACCTATGAATATGTGAAGTGGTTTTTGCATGCTGATTCATCTTCATATTTGACAC
CTATGAAACATATGTTGGCTGCCTCTGCTGGAGAAGTGGTTGCCTGCCTGATTCGAGTTCCATCTGAAGTGGTTAAGCAGAGGGCACAGG
TATCTGCTTCTACAAGAACATTTCAGATTTTCTCTAACATCTTATATGAAGAGGGTATCCAAGGGTTGTATCGAGGCTATAAAAGCACAG
TTTTAAGAGAGGTATCTCATTCAGTTGCTAAACTTATATTAGTTAATTTCCACTGGCAAGTTTCAGAGATATTGGACAGATACAAGTCCA
ATTCTGCTCAACTGCTTGTTGAGGCTCGAGTTCAGCCTAATCCATCAAAACATGTTCCCACATCCCATCCCCCTCACCACTGTGCAGTGT
GTATGCAGTTTGTGCGAAAGGAAAACCTACTCTCTCTGGCCTGTCAGCACCAGTTTTGCCGCAGCTGCTGGGAGCAGCACTGCTCAGTTC
TCGTCAAGGACGGCGTGGGCGTGGGAGTCTCTTGCATGGCTCAGGACTGTCCACTCCGTACACCAGAGGACTTTGTGTTTCCATTGCTTC
CCAATGAAGAATTGAGAGAGAAATACAGGCGCTACCTCTTCAGGGACTATGTGGAGAGTCATTACCAGCTCCAGCTGTGCCCTGGTGCAG
ACTGCCCCATGGTTATTCGGGTACAGGAGCCTAGAGCTCGCCGAGTACAGTGCAATCGGTGCAACGAGGTCTTCTGTTTCAAGTGTCGTC
AGATGTATCACGCACCCACAGACTGTGCCACAATCCGGAAATGGCTCACGAAGTGTGCAGACGACTCTGAAACAGCCAACTACATTAGTG
CTCACACTAAAGACTGTCCCAAGTGCAACATCTGCATTGAGAAGAATGGAGGCTGCAATCACATGCAATGCTCCAAATGTAAACACGACT
TCTGCTGGATGTGTCTAGGAGATTGGAAGACTCATGGCAGTGAATACTATGAGTGCAGTCGTTACAAGGAGAATCCTGACATCGTGAACC
AGAGCCAACAAGCCCAGGCGAGGGAAGCCCTCAAGAAGTACTTATTCTACTTTGAGAGGTGGGAAAACCACAATAAAAGCTTGCAGCTAG
AGGCACAGACATACCAGCGGATTCACGAGAAGATTCAGGAGAGGGTCATGAACAATCTGGGGACATGGATCGACTGGCAGTACCTACAGA
ATGCTGCCAAGCTCTTGGCCAAGTGTCGATACACCCTGCAATACACCTACCCATATGCATATTACATGGAGTCCGGACCCAGGAAGAAGC
TGTTTGAATACCAGCAGGCTCAGCTGGAGGCTGAGATCGAAAACCTCTCATGGAAAGTGGAGCGTGCAGACAGCTATGACAGAGGGGACT
TGGAGAACCAGATGCATATAGCGGAGCAGCGGAGGAGAACCCTGCTGAAAGATTTCCATGACACCTAAGTTGGGATGTGGATGTGCCGGG
GTGAGGAAGATGTGGCTGCAAGGTCTCCCGGCTGCCATACTGCATGCTGCAGGCTCTGCCTTTCATGACCCCAGGCAACAGCCAGGGCCC
CACTCCTGAGAGACACTGGCAACACCTCTTAGTTGATTTCTGTTTTCTTCTCTTTTCACTTTTTGTTTCTACCAGGGTAGAGGCCATGTT
GAACTGGCCTCTTTTCAGGACTTTTATTTCCCCCTGGATGGTTGTTGGGAGGGAGGGAAAGTGTTTTCTGAATGGCTATTAATAGTATTA
GATCATTACAACTTATGTAACTTTCAAAGGTTGTACAATTATACAAAAAAAAAAAAAAGGCAAACTATAGGATAACACAGAGCCCTTTTT
GAAAATAAATTGGCATTGGAGTGTTTTACCCTCTAGCTGTTTTACTTAGAATGTAACATATGCTGCCTACCCACCTCAAAATGTCTGTAC
TGCAAGAGGGCCCTGGGCCTCTGCTTTCCATATTCACGTTTGGCCAGAGTTGTAGTCCCAAAGAAGAGCATGGGTGGCAGATGGTAGGGA
ATTGAACTGGCCTGTGCAATGGGCATGGAGCACAAGGGGTCACAGCATGCCTCCTGCCTTACCGTGGCAGTACGGAGACAGTCCAGAACA
TGGTCTTCTTGCCACGGGGTGTTGTTGTCTCTGGTGGTGCTGCATGTCTGTGGCTCACCTTTATTCTTGAAACTGAGGTTTACCTGGATC
TGGCTACTGAGGCTAGAGCCCACAGCAGAATGGGGTTGGGCCTGTGGCCCCCCAAACTAGGGGGTGTGGGTTCATCACAGTGTTGCCTTT
TGTCTCCTAAAGATAGGGATCTACTTTTGAAGGGAATTGTTCCTCCCAAATAAATTTGCTTTACCTTGGTCCTTTCTTTTGTGCCAGTAT
TCAAGTGGTATAGCTCTGAGCAGGGTCACATTTGGCCAAACCTGACACTGTCTTGCTGCATTCTCCTTTGGCAAACATCAGGGTCAGAAT
TCAGGATAGCCCTTCCTAGGGCACTGGACTTTCTGGCATGGGGGCTGTGTTTGCACAAGTTATTTTCATGTTACCTGGAGAGTGTCCAGA
GGCTGCTCTGAGGCTGAGGTGTGTTCCCCCTTGCCTGGTTCCAGCTGTCAGAGGGATACCATCCTAGGGTCTGGGAATCCAAGGCCACGA
GACTCCTTGGTTTGTGGTCCGAGATCCTGTACTAAGGAGGGTCTGGCCAGAGGAACAGACCAGCTTTTGCACAATGAAGCGCAAGGGAAC
AAGTGGTTTGCCTGGTGTCCTACCTGTCCTGAACCTGGTCCTGTGGGCCATTGAAAAGTTAGATCTGTGATCTCTGGGGTTTTTGTGGCT
TTGTTCAATGCTTCCACTCTAGGGCAGGCAGAGCAGTCTATACTCTCCCAAGCCTGCTTGACCTCCAAGTAGAGCTGATACAGAGATCTG
TGAATATTGTGATAGAAATTCTTTGGTATTCATACATTTCAGCTGCAAGTCAGCAATTTCCCAGGTACCATGTAAGCTATAAAACAGTCA
TTCTTAAAGACAGAGGATAGCTGTGACTCATGGGATCATGAGGTCCATGGCTGGTTGCAGGTTCCCTTTTTCCTTCCTCAGGTTTTGTCT
CTTCCTGTGTTGTCCCCAGCAAGGGAGAGACTGTGGGGTGGATTGGGAGAACAGATTAGGAGTATAGCAAATGAACCCAGAATGGAACAG
TGGGGAGCTAACTGTGAATGAGGAGAGTACCTGCTGCAGGACCTGGAGGTCAGGTGTGAATGCTGTATTGGCACAGGGAATAAATATCCT
GGCGTCTGGAGCCTTCACCTCTCCGTCAAGTCCTTCCTGTGATACTGCCATGGCACAGGATCTGAGTTGCAGCTCTGCACCCTAAATCAC
ACCCTGGGCATTGTCTGGGCTGCAGGGCTGCCAGGTTCTGTACTTGTGTCCAGCTGTGGCCCTGGATGCTGGAGCTGGAGGGTTTTCTGT
GCTCAGACTGTAGCCTGTAGCTCTTGGCCTGTGTAGAGCCCCCTCCTGTGCCCTCAGTGGCTGTCGTTTGTTAACATCATCAGGAAGATG
GGAAAGGTCAGGCAGAATTTTTCTGCCCTACAAAGGGTGGAAGAGAAAGGACACAGTATTTTCATGAATTTACCATATATCTTTGTTTTT
CTTCAACGAAAAAGTTAATTGAGGCAATGTCATCTGCTCAAAGTTGAGTGGTTTATTCACAATAAACTGTAAGTTTCTGATTATAAAAAT
GTGTCTAGAGTCTTTCTTCATGGGGTCTAGGTAGTCTTCTGAGCCCACAGGGGTCTGGCCAGTGAACACCAGAGGAGTGCCTTCCTATCA
GTCAGCCCCTTCTTCCAGAGGGCTGTGGAGGCCCCAGTGGCCAAACTCGGCTCTGTTTTCCCTTTCTGGCTGTTGGGGGAGAGGGCACCT
GTAAGTGATCCCTGTGGAATGAAGTAGAAAATCCTGCCAGTTTTCCGCTCTCCTCTCCCTCAGTACAGGCTGAATCATTCCCCACCACAG
ATAGATCCCAGGGTTGTGGTAGAGTACTGATATAAATGTCCCAACCCCCCCATTCTGAGACCTCCGGACCCCTCCAAAGCAGACATGGGA
ATGTAGGGCTGTGGAATATGGCAGGGTGAACTCCAGCTTCACGGGAGCCCTAAGGGTTATGAAGAGACAACTTGGGGCAGAAACAAGTGT
GGAGTCTAATCTCAAGGGTGAAGGACAGGAAATGAGGTTTGGATTGATTAAGGGGGTCCACATTTGTGGTGTCAGAAGTGGCAGTAGTGT
CAGTGATAAGTAGCTCAGGGGTAGAGTGGAGGCTCCATAGCTGTGGGCAACATGCACAGGGCACCTGTGGCTAGAAGAGGCCTCATACAT
TGCCAGTCTGAACTCCGCAGCTCTTCCTCTGGACCTCAGGTGTGCCAAGCCCCACGCTTGGCACCTGGGCATACAGTGGTATGCAAGTGA
TTCACGTGCTCTAGCTTCCAGGAGCTTCCAATCCATGGGGAACATAGAAGGAATTGATCACTAGTGAATGTTTGTTTTTTGTTTTGAGAC

>82623_82623_3_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000354883_ARIH2_chr3_48999044_ENST00000356401_length(amino acids)=559AA_BP=151
MDRPGFVAALVAGGVAGVSVDLILFPLDTIKTRLQSPQGFSKAGGFHGIYAGVPSAAIGSFPNAAAFFITYEYVKWFLHADSSSYLTPMK
HMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTVLREVSHSVAKLILVNFHWQVSEILDRYKSNSA
QLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNE
ELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHT
KDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQ
TYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVERADSYDRGDLEN

--------------------------------------------------------------
>82623_82623_4_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000354883_ARIH2_chr3_48999044_ENST00000449376_length(transcript)=2758nt_BP=1181nt
AACCTGAAGCTCTCAGAGCTTCCCTGTCTTCATCTATCAGCCCAGGGAGAGGAATCAGTGGTTTTCCAAAAGCTGTACCTCTTTCCATAA
ATACAAGGATGAAGGGCTGAGATGATGGCAGTTAGAATTATATTGAGAAATGGTAGCGGGATCTGAGAAAGCAAGGCCATGAGTTGAAAG
CAGAGAGAAGGCGGTTCGAGTGGAGCCCTGATGAAGTTCATGCTCATGGTTGCCCAGCCATTAACACGGGCTCATCACATCTGTTTCCAG
ATTGCTTCTAGAACTTAGCTACCCTCGTTCTATAAGATGGAATGAAAATGCGTACTACATACAGATCATGAAAAGACGCAAAGAAAATGC
ATCTTCACATTGCAGTTCAGAATCACGCCGGCCTCATTCTACCGCTGCTCTCTCCTGGATCTCGGCCACGGATCTTTTGCTCGCGAAAGT
TCCTCCGTCTAGCTGCACACAACGCTGCTGCAGGAAACCGAGGTAAGGGATTTGCCGAGACTTAGCTCCACCACACTCCCCGAGGCCCCG
CCCCTCCTCTCTGGCCCTCCCCTAGGCCCAGGTGTCTCGCGTTGCACGTGCAGTTGTTGTGGTTCTACGTCACGTGGTCCCGGAAGTTCA
AGACAGACCCGCCTCAAACATGGCGGCGCCCAGCGCGCGAGGACGTGATCCGCTTCTGCTCCGGCTTGGATTGTAGCCTTGACGAGGTCT
GAGCGACCATGGACCGGCCGGGGTTCGTGGCAGCGCTGGTGGCTGGTGGGGTAGCAGGTGTTTCTGTTGACTTGATATTATTTCCTCTGG
ATACCATTAAAACCAGGCTGCAGAGTCCCCAAGGATTTAGTAAGGCTGGTGGTTTTCATGGAATATATGCTGGCGTTCCTTCTGCTGCTA
TTGGATCCTTTCCTAATGCTGCTGCATTTTTTATCACCTATGAATATGTGAAGTGGTTTTTGCATGCTGATTCATCTTCATATTTGACAC
CTATGAAACATATGTTGGCTGCCTCTGCTGGAGAAGTGGTTGCCTGCCTGATTCGAGTTCCATCTGAAGTGGTTAAGCAGAGGGCACAGG
TATCTGCTTCTACAAGAACATTTCAGATTTTCTCTAACATCTTATATGAAGAGGGTATCCAAGGGTTGTATCGAGGCTATAAAAGCACAG
TTTTAAGAGAGGTATCTCATTCAGTTGCTAAACTTATATTAGTTAATTTCCACTGGCAAGTTTCAGAGATATTGGACAGATACAAGTCCA
ATTCTGCTCAACTGCTTGTTGAGGCTCGAGTTCAGCCTAATCCATCAAAACATGTTCCCACATCCCATCCCCCTCACCACTGTGCAGTGT
GTATGCAGTTTGTGCGAAAGGAAAACCTACTCTCTCTGGCCTGTCAGCACCAGTTTTGCCGCAGCTGCTGGGAGCAGCACTGCTCAGTTC
TCGTCAAGGACGGCGTGGGCGTGGGAGTCTCTTGCATGGCTCAGGACTGTCCACTCCGTACACCAGAGGACTTTGTGTTTCCATTGCTTC
CCAATGAAGAATTGAGAGAGAAATACAGGCGCTACCTCTTCAGGGACTATGTGGAGAGTCATTACCAGCTCCAGCTGTGCCCTGGTGCAG
ACTGCCCCATGGTTATTCGGGTACAGGAGCCTAGAGCTCGCCGAGTACAGTGCAATCGGTGCAACGAGGTCTTCTGTTTCAAGTGTCGTC
AGATGTATCACGCACCCACAGACTGTGCCACAATCCGGAAATGGCTCACGAAGTGTGCAGACGACTCTGAAACAGCCAACTACATTAGTG
CTCACACTAAAGACTGTCCCAAGTGCAACATCTGCATTGAGAAGAATGGAGGCTGCAATCACATGCAATGCTCCAAATGTAAACACGACT
TCTGCTGGATGTGTCTAGGAGATTGGAAGACTCATGGCAGTGAATACTATGAGTGCAGTCGTTACAAGGAGAATCCTGACATCGTGAACC
AGAGCCAACAAGCCCAGGCGAGGGAAGCCCTCAAGAAGTACTTATTCTACTTTGAGAGGTGGGAAAACCACAATAAAAGCTTGCAGCTAG
AGGCACAGACATACCAGCGGATTCACGAGAAGATTCAGGAGAGGGTCATGAACAATCTGGGGACATGGATCGACTGGCAGTACCTACAGA
ATGCTGCCAAGCTCTTGGCCAAGTGTCGATACACCCTGCAATACACCTACCCATATGCATATTACATGGAGTCCGGACCCAGGAAGAAGC
TGTTTGAATACCAGCAGGCTCAGCTGGAGGCTGAGATCGAAAACCTCTCATGGAAAGTGGAGCGTGCAGACAGCTATGACAGAGGGGACT
TGGAGAACCAGATGCATATAGCGGAGCAGCGGAGGAGAACCCTGCTGAAAGATTTCCATGACACCTAAGTTGGGATGTGGATGTGCCGGG
GTGAGGAAGATGTGGCTGCAAGGTCTCCCGGCTGCCATACTGCATGCTGCAGGCTCTGCCTTTCATGACCCCAGGCAACAGCCAGGGCCC
CACTCCTGAGAGACACTGGCAACACCTCTTAGTTGATTTCTGTTTTCTTCTCTTTTCACTTTTTGTTTCTACCAGGGTAGAGGCCATGTT
GAACTGGCCTCTTTTCAGGACTTTTATTTCCCCCTGGATGGTTGTTGGGAGGGAGGGAAAGTGTTTTCTGAATGGCTATTAATAGTATTA

>82623_82623_4_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000354883_ARIH2_chr3_48999044_ENST00000449376_length(amino acids)=559AA_BP=151
MDRPGFVAALVAGGVAGVSVDLILFPLDTIKTRLQSPQGFSKAGGFHGIYAGVPSAAIGSFPNAAAFFITYEYVKWFLHADSSSYLTPMK
HMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTVLREVSHSVAKLILVNFHWQVSEILDRYKSNSA
QLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNE
ELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHT
KDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQ
TYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVERADSYDRGDLEN

--------------------------------------------------------------
>82623_82623_5_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000413054_ARIH2_chr3_48999044_ENST00000356401_length(transcript)=4602nt_BP=263nt
CTGCTGCATTTTTTATCACCTATGAATATGTGAAGTGGTTTTTGCATGCTGATTCATCTTCATATTTGACACCTATGAAACATATGTTGG
CTGCCTCTGCTGGAGAAGTGGTTGCCTGCCTGATTCGAGTTCCATCTGAAGTGGTTAAGCAGAGGGCACAGGTATCTGCTTCTACAAGAA
CATTTCAGATTTTCTCTAACATCTTATATGAAGAGGGTATCCAAGGGTTGTATCGAGGCTATAAAAGCACAGTTTTAAGAGAGGTATCTC
ATTCAGTTGCTAAACTTATATTAGTTAATTTCCACTGGCAAGTTTCAGAGATATTGGACAGATACAAGTCCAATTCTGCTCAACTGCTTG
TTGAGGCTCGAGTTCAGCCTAATCCATCAAAACATGTTCCCACATCCCATCCCCCTCACCACTGTGCAGTGTGTATGCAGTTTGTGCGAA
AGGAAAACCTACTCTCTCTGGCCTGTCAGCACCAGTTTTGCCGCAGCTGCTGGGAGCAGCACTGCTCAGTTCTCGTCAAGGACGGCGTGG
GCGTGGGAGTCTCTTGCATGGCTCAGGACTGTCCACTCCGTACACCAGAGGACTTTGTGTTTCCATTGCTTCCCAATGAAGAATTGAGAG
AGAAATACAGGCGCTACCTCTTCAGGGACTATGTGGAGAGTCATTACCAGCTCCAGCTGTGCCCTGGTGCAGACTGCCCCATGGTTATTC
GGGTACAGGAGCCTAGAGCTCGCCGAGTACAGTGCAATCGGTGCAACGAGGTCTTCTGTTTCAAGTGTCGTCAGATGTATCACGCACCCA
CAGACTGTGCCACAATCCGGAAATGGCTCACGAAGTGTGCAGACGACTCTGAAACAGCCAACTACATTAGTGCTCACACTAAAGACTGTC
CCAAGTGCAACATCTGCATTGAGAAGAATGGAGGCTGCAATCACATGCAATGCTCCAAATGTAAACACGACTTCTGCTGGATGTGTCTAG
GAGATTGGAAGACTCATGGCAGTGAATACTATGAGTGCAGTCGTTACAAGGAGAATCCTGACATCGTGAACCAGAGCCAACAAGCCCAGG
CGAGGGAAGCCCTCAAGAAGTACTTATTCTACTTTGAGAGGTGGGAAAACCACAATAAAAGCTTGCAGCTAGAGGCACAGACATACCAGC
GGATTCACGAGAAGATTCAGGAGAGGGTCATGAACAATCTGGGGACATGGATCGACTGGCAGTACCTACAGAATGCTGCCAAGCTCTTGG
CCAAGTGTCGATACACCCTGCAATACACCTACCCATATGCATATTACATGGAGTCCGGACCCAGGAAGAAGCTGTTTGAATACCAGCAGG
CTCAGCTGGAGGCTGAGATCGAAAACCTCTCATGGAAAGTGGAGCGTGCAGACAGCTATGACAGAGGGGACTTGGAGAACCAGATGCATA
TAGCGGAGCAGCGGAGGAGAACCCTGCTGAAAGATTTCCATGACACCTAAGTTGGGATGTGGATGTGCCGGGGTGAGGAAGATGTGGCTG
CAAGGTCTCCCGGCTGCCATACTGCATGCTGCAGGCTCTGCCTTTCATGACCCCAGGCAACAGCCAGGGCCCCACTCCTGAGAGACACTG
GCAACACCTCTTAGTTGATTTCTGTTTTCTTCTCTTTTCACTTTTTGTTTCTACCAGGGTAGAGGCCATGTTGAACTGGCCTCTTTTCAG
GACTTTTATTTCCCCCTGGATGGTTGTTGGGAGGGAGGGAAAGTGTTTTCTGAATGGCTATTAATAGTATTAGATCATTACAACTTATGT
AACTTTCAAAGGTTGTACAATTATACAAAAAAAAAAAAAAGGCAAACTATAGGATAACACAGAGCCCTTTTTGAAAATAAATTGGCATTG
GAGTGTTTTACCCTCTAGCTGTTTTACTTAGAATGTAACATATGCTGCCTACCCACCTCAAAATGTCTGTACTGCAAGAGGGCCCTGGGC
CTCTGCTTTCCATATTCACGTTTGGCCAGAGTTGTAGTCCCAAAGAAGAGCATGGGTGGCAGATGGTAGGGAATTGAACTGGCCTGTGCA
ATGGGCATGGAGCACAAGGGGTCACAGCATGCCTCCTGCCTTACCGTGGCAGTACGGAGACAGTCCAGAACATGGTCTTCTTGCCACGGG
GTGTTGTTGTCTCTGGTGGTGCTGCATGTCTGTGGCTCACCTTTATTCTTGAAACTGAGGTTTACCTGGATCTGGCTACTGAGGCTAGAG
CCCACAGCAGAATGGGGTTGGGCCTGTGGCCCCCCAAACTAGGGGGTGTGGGTTCATCACAGTGTTGCCTTTTGTCTCCTAAAGATAGGG
ATCTACTTTTGAAGGGAATTGTTCCTCCCAAATAAATTTGCTTTACCTTGGTCCTTTCTTTTGTGCCAGTATTCAAGTGGTATAGCTCTG
AGCAGGGTCACATTTGGCCAAACCTGACACTGTCTTGCTGCATTCTCCTTTGGCAAACATCAGGGTCAGAATTCAGGATAGCCCTTCCTA
GGGCACTGGACTTTCTGGCATGGGGGCTGTGTTTGCACAAGTTATTTTCATGTTACCTGGAGAGTGTCCAGAGGCTGCTCTGAGGCTGAG
GTGTGTTCCCCCTTGCCTGGTTCCAGCTGTCAGAGGGATACCATCCTAGGGTCTGGGAATCCAAGGCCACGAGACTCCTTGGTTTGTGGT
CCGAGATCCTGTACTAAGGAGGGTCTGGCCAGAGGAACAGACCAGCTTTTGCACAATGAAGCGCAAGGGAACAAGTGGTTTGCCTGGTGT
CCTACCTGTCCTGAACCTGGTCCTGTGGGCCATTGAAAAGTTAGATCTGTGATCTCTGGGGTTTTTGTGGCTTTGTTCAATGCTTCCACT
CTAGGGCAGGCAGAGCAGTCTATACTCTCCCAAGCCTGCTTGACCTCCAAGTAGAGCTGATACAGAGATCTGTGAATATTGTGATAGAAA
TTCTTTGGTATTCATACATTTCAGCTGCAAGTCAGCAATTTCCCAGGTACCATGTAAGCTATAAAACAGTCATTCTTAAAGACAGAGGAT
AGCTGTGACTCATGGGATCATGAGGTCCATGGCTGGTTGCAGGTTCCCTTTTTCCTTCCTCAGGTTTTGTCTCTTCCTGTGTTGTCCCCA
GCAAGGGAGAGACTGTGGGGTGGATTGGGAGAACAGATTAGGAGTATAGCAAATGAACCCAGAATGGAACAGTGGGGAGCTAACTGTGAA
TGAGGAGAGTACCTGCTGCAGGACCTGGAGGTCAGGTGTGAATGCTGTATTGGCACAGGGAATAAATATCCTGGCGTCTGGAGCCTTCAC
CTCTCCGTCAAGTCCTTCCTGTGATACTGCCATGGCACAGGATCTGAGTTGCAGCTCTGCACCCTAAATCACACCCTGGGCATTGTCTGG
GCTGCAGGGCTGCCAGGTTCTGTACTTGTGTCCAGCTGTGGCCCTGGATGCTGGAGCTGGAGGGTTTTCTGTGCTCAGACTGTAGCCTGT
AGCTCTTGGCCTGTGTAGAGCCCCCTCCTGTGCCCTCAGTGGCTGTCGTTTGTTAACATCATCAGGAAGATGGGAAAGGTCAGGCAGAAT
TTTTCTGCCCTACAAAGGGTGGAAGAGAAAGGACACAGTATTTTCATGAATTTACCATATATCTTTGTTTTTCTTCAACGAAAAAGTTAA
TTGAGGCAATGTCATCTGCTCAAAGTTGAGTGGTTTATTCACAATAAACTGTAAGTTTCTGATTATAAAAATGTGTCTAGAGTCTTTCTT
CATGGGGTCTAGGTAGTCTTCTGAGCCCACAGGGGTCTGGCCAGTGAACACCAGAGGAGTGCCTTCCTATCAGTCAGCCCCTTCTTCCAG
AGGGCTGTGGAGGCCCCAGTGGCCAAACTCGGCTCTGTTTTCCCTTTCTGGCTGTTGGGGGAGAGGGCACCTGTAAGTGATCCCTGTGGA
ATGAAGTAGAAAATCCTGCCAGTTTTCCGCTCTCCTCTCCCTCAGTACAGGCTGAATCATTCCCCACCACAGATAGATCCCAGGGTTGTG
GTAGAGTACTGATATAAATGTCCCAACCCCCCCATTCTGAGACCTCCGGACCCCTCCAAAGCAGACATGGGAATGTAGGGCTGTGGAATA
TGGCAGGGTGAACTCCAGCTTCACGGGAGCCCTAAGGGTTATGAAGAGACAACTTGGGGCAGAAACAAGTGTGGAGTCTAATCTCAAGGG
TGAAGGACAGGAAATGAGGTTTGGATTGATTAAGGGGGTCCACATTTGTGGTGTCAGAAGTGGCAGTAGTGTCAGTGATAAGTAGCTCAG
GGGTAGAGTGGAGGCTCCATAGCTGTGGGCAACATGCACAGGGCACCTGTGGCTAGAAGAGGCCTCATACATTGCCAGTCTGAACTCCGC
AGCTCTTCCTCTGGACCTCAGGTGTGCCAAGCCCCACGCTTGGCACCTGGGCATACAGTGGTATGCAAGTGATTCACGTGCTCTAGCTTC
CAGGAGCTTCCAATCCATGGGGAACATAGAAGGAATTGATCACTAGTGAATGTTTGTTTTTTGTTTTGAGACAGTCTCGCTCTATCGCCC

>82623_82623_5_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000413054_ARIH2_chr3_48999044_ENST00000356401_length(amino acids)=482AA_BP=74
MHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTVLREVSHSVAKLILVNFHWQ
VSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLR
TPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCA
DDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFER
WENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKV

--------------------------------------------------------------
>82623_82623_6_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000413054_ARIH2_chr3_48999044_ENST00000449376_length(transcript)=1840nt_BP=263nt
CTGCTGCATTTTTTATCACCTATGAATATGTGAAGTGGTTTTTGCATGCTGATTCATCTTCATATTTGACACCTATGAAACATATGTTGG
CTGCCTCTGCTGGAGAAGTGGTTGCCTGCCTGATTCGAGTTCCATCTGAAGTGGTTAAGCAGAGGGCACAGGTATCTGCTTCTACAAGAA
CATTTCAGATTTTCTCTAACATCTTATATGAAGAGGGTATCCAAGGGTTGTATCGAGGCTATAAAAGCACAGTTTTAAGAGAGGTATCTC
ATTCAGTTGCTAAACTTATATTAGTTAATTTCCACTGGCAAGTTTCAGAGATATTGGACAGATACAAGTCCAATTCTGCTCAACTGCTTG
TTGAGGCTCGAGTTCAGCCTAATCCATCAAAACATGTTCCCACATCCCATCCCCCTCACCACTGTGCAGTGTGTATGCAGTTTGTGCGAA
AGGAAAACCTACTCTCTCTGGCCTGTCAGCACCAGTTTTGCCGCAGCTGCTGGGAGCAGCACTGCTCAGTTCTCGTCAAGGACGGCGTGG
GCGTGGGAGTCTCTTGCATGGCTCAGGACTGTCCACTCCGTACACCAGAGGACTTTGTGTTTCCATTGCTTCCCAATGAAGAATTGAGAG
AGAAATACAGGCGCTACCTCTTCAGGGACTATGTGGAGAGTCATTACCAGCTCCAGCTGTGCCCTGGTGCAGACTGCCCCATGGTTATTC
GGGTACAGGAGCCTAGAGCTCGCCGAGTACAGTGCAATCGGTGCAACGAGGTCTTCTGTTTCAAGTGTCGTCAGATGTATCACGCACCCA
CAGACTGTGCCACAATCCGGAAATGGCTCACGAAGTGTGCAGACGACTCTGAAACAGCCAACTACATTAGTGCTCACACTAAAGACTGTC
CCAAGTGCAACATCTGCATTGAGAAGAATGGAGGCTGCAATCACATGCAATGCTCCAAATGTAAACACGACTTCTGCTGGATGTGTCTAG
GAGATTGGAAGACTCATGGCAGTGAATACTATGAGTGCAGTCGTTACAAGGAGAATCCTGACATCGTGAACCAGAGCCAACAAGCCCAGG
CGAGGGAAGCCCTCAAGAAGTACTTATTCTACTTTGAGAGGTGGGAAAACCACAATAAAAGCTTGCAGCTAGAGGCACAGACATACCAGC
GGATTCACGAGAAGATTCAGGAGAGGGTCATGAACAATCTGGGGACATGGATCGACTGGCAGTACCTACAGAATGCTGCCAAGCTCTTGG
CCAAGTGTCGATACACCCTGCAATACACCTACCCATATGCATATTACATGGAGTCCGGACCCAGGAAGAAGCTGTTTGAATACCAGCAGG
CTCAGCTGGAGGCTGAGATCGAAAACCTCTCATGGAAAGTGGAGCGTGCAGACAGCTATGACAGAGGGGACTTGGAGAACCAGATGCATA
TAGCGGAGCAGCGGAGGAGAACCCTGCTGAAAGATTTCCATGACACCTAAGTTGGGATGTGGATGTGCCGGGGTGAGGAAGATGTGGCTG
CAAGGTCTCCCGGCTGCCATACTGCATGCTGCAGGCTCTGCCTTTCATGACCCCAGGCAACAGCCAGGGCCCCACTCCTGAGAGACACTG
GCAACACCTCTTAGTTGATTTCTGTTTTCTTCTCTTTTCACTTTTTGTTTCTACCAGGGTAGAGGCCATGTTGAACTGGCCTCTTTTCAG
GACTTTTATTTCCCCCTGGATGGTTGTTGGGAGGGAGGGAAAGTGTTTTCTGAATGGCTATTAATAGTATTAGATCATTACAACTTATGT

>82623_82623_6_SLC25A26-ARIH2_SLC25A26_chr3_66313803_ENST00000413054_ARIH2_chr3_48999044_ENST00000449376_length(amino acids)=482AA_BP=74
MHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTVLREVSHSVAKLILVNFHWQ
VSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLR
TPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCA
DDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFER
WENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SLC25A26-ARIH2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SLC25A26-ARIH2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SLC25A26-ARIH2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource