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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ATP9A-ZFP64 (FusionGDB2 ID:8292)

Fusion Gene Summary for ATP9A-ZFP64

check button Fusion gene summary
Fusion gene informationFusion gene name: ATP9A-ZFP64
Fusion gene ID: 8292
HgeneTgene
Gene symbol

ATP9A

ZFP64

Gene ID

10079

55734

Gene nameATPase phospholipid transporting 9A (putative)ZFP64 zinc finger protein
SynonymsATPIIAZNF338
Cytomap

20q13.2

20q13.2

Type of geneprotein-codingprotein-coding
Descriptionprobable phospholipid-transporting ATPase IIAATPase type IV, phospholipid-transporting (P-type),(putative)ATPase, class II, type 9Aphospholipid-transporting ATPase IIAzinc finger protein 64zinc finger protein 338zinc finger protein 64 homolog
Modification date2020031320200327
UniProtAcc

O75110

.
Ensembl transtripts involved in fusion geneENST00000311637, ENST00000338821, 
ENST00000402822, ENST00000477492, 
ENST00000371523, ENST00000477786, 
ENST00000216923, ENST00000346617, 
ENST00000371515, ENST00000361387, 
ENST00000371518, 
Fusion gene scores* DoF score15 X 13 X 10=19505 X 5 X 3=75
# samples 166
** MAII scorelog2(16/1950*10)=-3.60733031374961
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/75*10)=-0.321928094887362
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATP9A [Title/Abstract] AND ZFP64 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATP9A(50342358)-ZFP64(50715126), # samples:1
Anticipated loss of major functional domain due to fusion event.ATP9A-ZFP64 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ATP9A-ZFP64 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ATP9A-ZFP64 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ATP9A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZFP64 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCSTCGA-NF-A5CP-01AATP9Achr20

50342358

-ZFP64chr20

50715126

-


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Fusion Gene ORF analysis for ATP9A-ZFP64

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000311637ENST00000371523ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-5UTRENST00000311637ENST00000477786ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-5UTRENST00000338821ENST00000371523ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-5UTRENST00000338821ENST00000477786ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-5UTRENST00000402822ENST00000371523ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-5UTRENST00000402822ENST00000477786ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-5UTRENST00000477492ENST00000371523ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-5UTRENST00000477492ENST00000477786ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000311637ENST00000216923ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000311637ENST00000346617ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000311637ENST00000371515ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000338821ENST00000216923ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000338821ENST00000346617ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000338821ENST00000371515ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000402822ENST00000216923ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000402822ENST00000346617ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000402822ENST00000371515ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000477492ENST00000216923ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000477492ENST00000346617ATP9Achr20

50342358

-ZFP64chr20

50715126

-
5CDS-intronENST00000477492ENST00000371515ATP9Achr20

50342358

-ZFP64chr20

50715126

-
Frame-shiftENST00000311637ENST00000361387ATP9Achr20

50342358

-ZFP64chr20

50715126

-
Frame-shiftENST00000311637ENST00000371518ATP9Achr20

50342358

-ZFP64chr20

50715126

-
Frame-shiftENST00000338821ENST00000361387ATP9Achr20

50342358

-ZFP64chr20

50715126

-
Frame-shiftENST00000338821ENST00000371518ATP9Achr20

50342358

-ZFP64chr20

50715126

-
Frame-shiftENST00000402822ENST00000361387ATP9Achr20

50342358

-ZFP64chr20

50715126

-
Frame-shiftENST00000402822ENST00000371518ATP9Achr20

50342358

-ZFP64chr20

50715126

-
In-frameENST00000477492ENST00000361387ATP9Achr20

50342358

-ZFP64chr20

50715126

-
In-frameENST00000477492ENST00000371518ATP9Achr20

50342358

-ZFP64chr20

50715126

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000477492ATP9Achr2050342358-ENST00000371518ZFP64chr2050715126-1405470214954246
ENST00000477492ATP9Achr2050342358-ENST00000361387ZFP64chr2050715126-21914702141644476

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000477492ENST00000371518ATP9Achr2050342358-ZFP64chr2050715126-0.0796512140.92034876
ENST00000477492ENST00000361387ATP9Achr2050342358-ZFP64chr2050715126-0.065103660.93489635

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Fusion Genomic Features for ATP9A-ZFP64


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ATP9A-ZFP64


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:50342358/chr20:50715126)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATP9A

O75110

.
FUNCTION: Plays a role in regulating membrane trafficking of cargo proteins, namely endosome to plasma membrane recycling and endosome to trans-Golgi network retrograde transport (PubMed:27733620, PubMed:30213940). In complex with MON2 and DOP1B, regulates SNX3 retromer-mediated endosomal sorting of WLS, a transporter of Wnt morphogens in developing tissues. Participates in the formation of endosomal carriers that direct WLS trafficking back to Golgi, away from lysosomal degradation (PubMed:30213940). Appears to be implicated in intercellular communication by negatively regulating the release of exosomes (PubMed:30947313). The flippase activity towards membrane lipids and its role in membrane asymmetry remains to be proved (PubMed:30947313). {ECO:0000269|PubMed:27733620, ECO:0000269|PubMed:30213940, ECO:0000269|PubMed:30947313}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-3282_691091048.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-32892_961091048.0Topological domainExtracellular
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-3232_69109927.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-32392_96109927.0Topological domainExtracellular
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-32870_911091048.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-32370_91109927.0TransmembraneHelical
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749299_324254646.0Zinc fingerC2H2-type 4%3B atypical
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749330_352254646.0Zinc fingerC2H2-type 5
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749358_380254646.0Zinc fingerC2H2-type 6
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749386_408254646.0Zinc fingerC2H2-type 7
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749414_436254646.0Zinc fingerC2H2-type 8
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749442_465254646.0Zinc fingerC2H2-type 9
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749467_489254646.0Zinc fingerC2H2-type 10
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749495_517254646.0Zinc fingerC2H2-type 11
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749523_546254646.0Zinc fingerC2H2-type 12
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749580_602254646.0Zinc fingerC2H2-type 13
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506175_1970680.0Zinc fingerC2H2-type 1
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506203_2250680.0Zinc fingerC2H2-type 2
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506231_2530680.0Zinc fingerC2H2-type 3
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506299_3240680.0Zinc fingerC2H2-type 4%3B atypical
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506330_3520680.0Zinc fingerC2H2-type 5
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506358_3800680.0Zinc fingerC2H2-type 6
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506386_4080680.0Zinc fingerC2H2-type 7
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506414_4360680.0Zinc fingerC2H2-type 8
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506442_4650680.0Zinc fingerC2H2-type 9
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506467_4890680.0Zinc fingerC2H2-type 10
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506495_5170680.0Zinc fingerC2H2-type 11
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506523_5460680.0Zinc fingerC2H2-type 12
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151506580_6020680.0Zinc fingerC2H2-type 13
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849299_324254416.0Zinc fingerC2H2-type 4%3B atypical
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849330_352254416.0Zinc fingerC2H2-type 5
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849358_380254416.0Zinc fingerC2H2-type 6
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849386_408254416.0Zinc fingerC2H2-type 7
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849414_436254416.0Zinc fingerC2H2-type 8
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849442_465254416.0Zinc fingerC2H2-type 9
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849467_489254416.0Zinc fingerC2H2-type 10
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849495_517254416.0Zinc fingerC2H2-type 11
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849523_546254416.0Zinc fingerC2H2-type 12
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849580_602254416.0Zinc fingerC2H2-type 13
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305175_19735427.0Zinc fingerC2H2-type 1
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305203_22535427.0Zinc fingerC2H2-type 2
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305231_25335427.0Zinc fingerC2H2-type 3
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305299_32435427.0Zinc fingerC2H2-type 4%3B atypical
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305330_35235427.0Zinc fingerC2H2-type 5
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305358_38035427.0Zinc fingerC2H2-type 6
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305386_40835427.0Zinc fingerC2H2-type 7
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305414_43635427.0Zinc fingerC2H2-type 8
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305442_46535427.0Zinc fingerC2H2-type 9
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305467_48935427.0Zinc fingerC2H2-type 10
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305495_51735427.0Zinc fingerC2H2-type 11
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305523_54635427.0Zinc fingerC2H2-type 12
TgeneZFP64chr20:50342358chr20:50715126ENST0000037152305580_60235427.0Zinc fingerC2H2-type 13

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-3281000_10061091048.0Topological domainExtracellular
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-3281031_10471091048.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328120_3031091048.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328326_3321091048.0Topological domainExtracellular
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328355_8411091048.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328863_8741091048.0Topological domainExtracellular
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328894_9231091048.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328943_9491091048.0Topological domainExtracellular
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328973_9781091048.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-3231000_1006109927.0Topological domainExtracellular
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-3231031_1047109927.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323120_303109927.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323326_332109927.0Topological domainExtracellular
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323355_841109927.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323863_874109927.0Topological domainExtracellular
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323894_923109927.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323943_949109927.0Topological domainExtracellular
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323973_978109927.0Topological domainCytoplasmic
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-3281007_10301091048.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328304_3251091048.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328333_3541091048.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328842_8621091048.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328875_8931091048.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328924_9421091048.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328950_9721091048.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-328979_9991091048.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000338821-32897_1191091048.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-3231007_1030109927.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323304_325109927.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323333_354109927.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323842_862109927.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323875_893109927.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323924_942109927.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323950_972109927.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-323979_999109927.0TransmembraneHelical
HgeneATP9Achr20:50342358chr20:50715126ENST00000402822-32397_119109927.0TransmembraneHelical
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749175_197254646.0Zinc fingerC2H2-type 1
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749203_225254646.0Zinc fingerC2H2-type 2
TgeneZFP64chr20:50342358chr20:50715126ENST0000036138749231_253254646.0Zinc fingerC2H2-type 3
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849175_197254416.0Zinc fingerC2H2-type 1
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849203_225254416.0Zinc fingerC2H2-type 2
TgeneZFP64chr20:50342358chr20:50715126ENST0000037151849231_253254416.0Zinc fingerC2H2-type 3


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Fusion Gene Sequence for ATP9A-ZFP64


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8292_8292_1_ATP9A-ZFP64_ATP9A_chr20_50342358_ENST00000477492_ZFP64_chr20_50715126_ENST00000361387_length(transcript)=2191nt_BP=470nt
TTTACTGGAATGAGGATGCTATTTTTAAGAAAGAGCATTGTGTTTCATCATGGAAATTTTGAGCATCTGAGCAGGCAGCCTGCTGGCTCG
CTCATCTTTAAGGTCCTGATGGACAGAGGCTGTGTTTTCTTAGCTCTGTACCCCAGCACCCACCAGGACCTGCTCTGTGGGAACAAGGGA
AGAAGGAAGGTCTGTGGTGGACGAGTAATATGTGCTGCGAGTGGCTGAGATGCTGCGGTGGAGGGGAGGCCAGGCCCCGCACTGTCTGGC
TGGGGCACCCCGAGAAGAGAGACCAGAGGTATCCTCGGAATGTCATCAACAATCAGAAGTACAATTTCTTCACCTTTCTTCCTGGGGTGC
TGTTCAACCAGTTCAAATACTTTTTCAACCTCTATTTCTTACTTCTTGCCTGCTCTCAGTTTGTTCCCGAAATGAGACTTGGTGCACTCT
ATACCTACTGGGTTCCCCTGCTTCAGAACTTGATGATGATGTTCCAAAAGCAAACTGCCTCTCCACTGAAAGCACTGACACTCCGAAGGC
CCCTGTCATCACTCTTCCCTCAGAGGCAAGGGAACAAATGGCCACCCTTGGAGAGAGGACGTTCAACTGTTGCTACCCAGGTTGCCACTT
CAAAACTGTCCATGGCATGAAAGACTTGGACCGCCATCTCAGAATCCACACGGGAGACAAACCGCACAAGTGTGAGTTCTGTGACAAGTG
CTTCAGCCGGAAGGACAACCTGACCATGCACATGCGGTGCCACACCAGTGTGAAGCCACACAAGTGTCACCTGTGTGACTACGCTGCCGT
GGACAGCAGTAGCCTCAAGAAGCACCTGCGGATCCACTCTGATGAGCGGCCGTACAAATGCCAGCTCTGCCCCTATGCCAGCCGCAACTC
CAGCCAGCTCACCGTCCACCTGCGATCTCACACGGGGGATACCCCCTTCCAGTGCTGGCTCTGTAGCGCCAAGTTCAAAATCAGCTCGGA
CTTGAAAAGGCACATGATCGTGCACTCGGGGGAGAAGCCTTTCAAGTGCGAGTTCTGCGACGTCCGCTGCACCATGAAGGCGAATCTCAA
ATCGCACATCCGCATCAAGCACACCTTCAAATGTCTGCACTGTGCCTTCCAGGGCCGGGACCGGGCTGACCTCCTGGAGCACAGCCGGCT
GCACCAGGCCGACCACCCGGAGAAGTGTCCAGAGTGCAGCTACTCCTGCTCCAGCGCGGCCGCCCTGCGCGTGCACAGCAGAGTCCACTG
TAAGGACCGTCCCTTCAAGTGTGACTTCTGCAGCTTCGACACGAAGCGGCCCAGCAGCCTGGCCAAGCACGTCGACAAGGTGCACAGGGA
CGAGGCCAAGACGGAGAACCGGGCCCCTCTGGGCAAGGAAGGGCTCAGAGAGGGCAGCTCCCAGCACGTGGCCAAGATCGTGACGCAGAG
GGCCTTCCGCTGTGAGACCTGCGGCGCCTCCTTCGTCAGGGATGACTCTCTGAGATGCCACAAGAAGCAGCACAGTGATCAGAGTGAGAA
CAAGAACTCAGACTTGGTCACCTTCCCACCGGAAAGCGGTGCCTCGGGACAGCTCAGCACCCTGGTCTCCGTGGGGCAGCTCGAGGCTCC
CCTAGAGCCCAGCCAAGACCTCTAGCTCAGCCGAAGAGGGTGGTCAGCTGTCGGAACTTCTGACCAGTGCTGTTGCCCAGCCCTCCAGAG
GTGAGGCCACTGAGAGACAGGCTTTGGGCACCACTTCTGGGGCTGGCCGCTCCAACTTCACAGGCCTTCAGAGGCGATGGCTGGGCGACA
GTGACGAAAGCAAAGCAAAGCAGGGCTGTGGAGACACTCCTCGCATTTGTCTCTTCCCTCCAAGGATTATCTGAGCAAGTCGACTTGTTC
ATTCAAAGGCGGGGTCTGCCAAGCCCTGCTCTATCCAATGGGGATAGCTTCTACGTAACGGATTCCAATTTTAAAACTGATCCATCTCTG
ATGGAATTATTAAACTTAGACGATATAGAAAACTAAAACTAATCTCTAGAGTGGAAAGGGTTAAAGTGAGGAAGGTGTACGTGAAGGGTC
TGGGGTTGCTGGAAAACTTCTATTTCATAACCTGGGTGATCGTTCTAAGAGTGTTTGCCTTATATGTTTGTGTGGTTTCTTTTACCTGTT

>8292_8292_1_ATP9A-ZFP64_ATP9A_chr20_50342358_ENST00000477492_ZFP64_chr20_50715126_ENST00000361387_length(amino acids)=476AA_BP=85
MRVAEMLRWRGGQAPHCLAGAPREERPEVSSECHQQSEVQFLHLSSWGAVQPVQILFQPLFLTSCLLSVCSRNETWCTLYLLGSPASELD
DDVPKANCLSTESTDTPKAPVITLPSEAREQMATLGERTFNCCYPGCHFKTVHGMKDLDRHLRIHTGDKPHKCEFCDKCFSRKDNLTMHM
RCHTSVKPHKCHLCDYAAVDSSSLKKHLRIHSDERPYKCQLCPYASRNSSQLTVHLRSHTGDTPFQCWLCSAKFKISSDLKRHMIVHSGE
KPFKCEFCDVRCTMKANLKSHIRIKHTFKCLHCAFQGRDRADLLEHSRLHQADHPEKCPECSYSCSSAAALRVHSRVHCKDRPFKCDFCS
FDTKRPSSLAKHVDKVHRDEAKTENRAPLGKEGLREGSSQHVAKIVTQRAFRCETCGASFVRDDSLRCHKKQHSDQSENKNSDLVTFPPE

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>8292_8292_2_ATP9A-ZFP64_ATP9A_chr20_50342358_ENST00000477492_ZFP64_chr20_50715126_ENST00000371518_length(transcript)=1405nt_BP=470nt
TTTACTGGAATGAGGATGCTATTTTTAAGAAAGAGCATTGTGTTTCATCATGGAAATTTTGAGCATCTGAGCAGGCAGCCTGCTGGCTCG
CTCATCTTTAAGGTCCTGATGGACAGAGGCTGTGTTTTCTTAGCTCTGTACCCCAGCACCCACCAGGACCTGCTCTGTGGGAACAAGGGA
AGAAGGAAGGTCTGTGGTGGACGAGTAATATGTGCTGCGAGTGGCTGAGATGCTGCGGTGGAGGGGAGGCCAGGCCCCGCACTGTCTGGC
TGGGGCACCCCGAGAAGAGAGACCAGAGGTATCCTCGGAATGTCATCAACAATCAGAAGTACAATTTCTTCACCTTTCTTCCTGGGGTGC
TGTTCAACCAGTTCAAATACTTTTTCAACCTCTATTTCTTACTTCTTGCCTGCTCTCAGTTTGTTCCCGAAATGAGACTTGGTGCACTCT
ATACCTACTGGGTTCCCCTGCTTCAGAACTTGATGATGATGTTCCAAAAGCAAACTGCCTCTCCACTGAAAGCACTGACACTCCGAAGGC
CCCTGTCATCACTCTTCCCTCAGAGGCAAGGGAACAAATGGCCACCCTTGGAGAGAGGACGTTCAACTGTTGCTACCCAGGTTGCCACTT
CAAAACTGTCCATGGCATGAAAGACTTGGACCGCCATCTCAGAATCCACACGGGAGACAAACCGCACAAGTGTGAGTTCTGTGACAAGTG
CTTCAGCCGGAAGGACAACCTGACCATGCACATGCGGTGCCACACCAGTGTGAAGCCACACAAGTGTCACCTGTGTGACTACGCTGCCGT
GGACAGCAGTAGCCTCAAGAAGCACCTGCGGATCCACTCTGATGAGCGGCCGTACAAATGCCAGCTCTGCCCCTATGCCAGCCGCAACTC
CAGCCAGCTCACCGTCCACCTGCGATCTCACACGGGGTGTTGCTATGTTGCCTAGATGGAATGCAGTGGCATGATCACAGCTCACTGCAG
CCTCGACCTCCTGGACTCAAGCAATCCTCCTCCTCCTGCCCCAGCCTCCCAAATAGCTGGGACCACAGGCATGTGCCACCACGCCCAGCT
AATTTTTTTATTTTTTATAGAAACGAGGTCTTGCTCTGTTGCCCAGGCTGGTCTCAAACTCGTGGGCTCAAGTGATTCTCCTGCCTTAGC
CTTCTGAAATGCTATGATTACAGGCACGAGCCACCGTGCCTGGCCTATTTTTTTAATATTTTTAAAGATTTGTAAAACAAAGAAGCATGT
ATGGACCACAAAGCCTAGTACTACCTGGCTCTTTACCAAAAAAAAAAAAAAAAAAATTGCCACATCCAGGTCAGTAGAACATAAATTATG

>8292_8292_2_ATP9A-ZFP64_ATP9A_chr20_50342358_ENST00000477492_ZFP64_chr20_50715126_ENST00000371518_length(amino acids)=246AA_BP=85
MRVAEMLRWRGGQAPHCLAGAPREERPEVSSECHQQSEVQFLHLSSWGAVQPVQILFQPLFLTSCLLSVCSRNETWCTLYLLGSPASELD
DDVPKANCLSTESTDTPKAPVITLPSEAREQMATLGERTFNCCYPGCHFKTVHGMKDLDRHLRIHTGDKPHKCEFCDKCFSRKDNLTMHM

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Fusion Gene PPI Analysis for ATP9A-ZFP64


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATP9A-ZFP64


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATP9A-ZFP64


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource