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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SLC35E1-EPS15L1 (FusionGDB2 ID:82968)

Fusion Gene Summary for SLC35E1-EPS15L1

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC35E1-EPS15L1
Fusion gene ID: 82968
HgeneTgene
Gene symbol

SLC35E1

EPS15L1

Gene ID

79939

58513

Gene namesolute carrier family 35 member E1epidermal growth factor receptor pathway substrate 15 like 1
Synonyms-EPS15R
Cytomap

19p13.11

19p13.11

Type of geneprotein-codingprotein-coding
Descriptionsolute carrier family 35 member E1epidermal growth factor receptor substrate 15-like 1epidermal growth factor receptor substrate EPS15Reps15-related protein
Modification date2020031320200313
UniProtAcc.

Q9UBC2

Ensembl transtripts involved in fusion geneENST00000595753, ENST00000431408, 
ENST00000593812, 		ENST00000248070, 
ENST00000455140, ENST00000535753, 
ENST00000594975, ENST00000597937, 
ENST00000602009, 
Fusion gene scores* DoF score7 X 7 X 4=19612 X 10 X 6=720
# samples 813
** MAII scorelog2(8/196*10)=-1.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/720*10)=-2.46948528330122
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC35E1 [Title/Abstract] AND EPS15L1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEPS15L1(16582723)-SLC35E1(16666208), # samples:1
SLC35E1(16677343)-EPS15L1(16528915), # samples:1
Anticipated loss of major functional domain due to fusion event.SLC35E1-EPS15L1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
SLC35E1-EPS15L1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SLC35E1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EPS15L1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-UB-A7MB-01ASLC35E1chr19

16677343

-EPS15L1chr19

16528915

-


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Fusion Gene ORF analysis for SLC35E1-EPS15L1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000595753ENST00000248070SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
Frame-shiftENST00000595753ENST00000455140SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
Frame-shiftENST00000595753ENST00000535753SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
Frame-shiftENST00000595753ENST00000594975SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
Frame-shiftENST00000595753ENST00000597937SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
Frame-shiftENST00000595753ENST00000602009SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
In-frameENST00000431408ENST00000248070SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
In-frameENST00000431408ENST00000455140SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
In-frameENST00000431408ENST00000535753SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
In-frameENST00000431408ENST00000594975SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
In-frameENST00000431408ENST00000597937SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
In-frameENST00000431408ENST00000602009SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
intron-3CDSENST00000593812ENST00000248070SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
intron-3CDSENST00000593812ENST00000455140SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
intron-3CDSENST00000593812ENST00000535753SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
intron-3CDSENST00000593812ENST00000594975SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
intron-3CDSENST00000593812ENST00000597937SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-
intron-3CDSENST00000593812ENST00000602009SLC35E1chr19

16677343

-EPS15L1chr19

16528915

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000431408SLC35E1chr1916677343-ENST00000455140EPS15L1chr1916528915-28175685722350592
ENST00000431408SLC35E1chr1916677343-ENST00000248070EPS15L1chr1916528915-24025685722212546
ENST00000431408SLC35E1chr1916677343-ENST00000535753EPS15L1chr1916528915-22535685721882436
ENST00000431408SLC35E1chr1916677343-ENST00000594975EPS15L1chr1916528915-19675685721888438
ENST00000431408SLC35E1chr1916677343-ENST00000602009EPS15L1chr1916528915-30995685721423283
ENST00000431408SLC35E1chr1916677343-ENST00000597937EPS15L1chr1916528915-30995685721423283

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000431408ENST00000455140SLC35E1chr1916677343-EPS15L1chr1916528915-0.0072247620.9927752
ENST00000431408ENST00000248070SLC35E1chr1916677343-EPS15L1chr1916528915-0.0055887060.9944113
ENST00000431408ENST00000535753SLC35E1chr1916677343-EPS15L1chr1916528915-0.0049657990.9950342
ENST00000431408ENST00000594975SLC35E1chr1916677343-EPS15L1chr1916528915-0.0053880980.994612
ENST00000431408ENST00000602009SLC35E1chr1916677343-EPS15L1chr1916528915-0.0031784180.9968215
ENST00000431408ENST00000597937SLC35E1chr1916677343-EPS15L1chr1916528915-0.0031784180.9968215

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Fusion Genomic Features for SLC35E1-EPS15L1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SLC35E1-EPS15L1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:16582723/chr19:16666208)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EPS15L1

Q9UBC2

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. {ECO:0000269|PubMed:22648170, ECO:0000269|PubMed:9407958}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000431408-4550_7096105.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000595753-46111_131252411.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000595753-46133_153252411.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000595753-46165_184252411.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000595753-46188_207252411.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000595753-46222_242252411.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000595753-4650_70252411.0TransmembraneHelical
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923386_553316865.0Coiled coilOntology_term=ECO:0000255
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924386_553316911.0Coiled coilOntology_term=ECO:0000255
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922386_553316755.0Coiled coilOntology_term=ECO:0000255
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916386_553316602.0Coiled coilOntology_term=ECO:0000255
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923750_816316865.0Compositional biasNote=Pro-rich
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924750_816316911.0Compositional biasNote=Pro-rich
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922750_816316755.0Compositional biasNote=Pro-rich
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916750_816316602.0Compositional biasNote=Pro-rich
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923618_835316865.0RegionNote=15 X 3 AA repeats of D-P-F
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924618_835316911.0RegionNote=15 X 3 AA repeats of D-P-F
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922618_835316755.0RegionNote=15 X 3 AA repeats of D-P-F
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916618_835316602.0RegionNote=15 X 3 AA repeats of D-P-F
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923618_620316865.0RepeatNote=1
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923640_642316865.0RepeatNote=2
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923645_647316865.0RepeatNote=3
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923650_652316865.0RepeatNote=4
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923656_658316865.0RepeatNote=5
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923661_663316865.0RepeatNote=6
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923667_669316865.0RepeatNote=7
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923685_687316865.0RepeatNote=8
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923690_692316865.0RepeatNote=9
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923709_711316865.0RepeatNote=10
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923728_730316865.0RepeatNote=11
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923754_756316865.0RepeatNote=12
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923806_808316865.0RepeatNote=13
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923812_814316865.0RepeatNote=14
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923833_835316865.0RepeatNote=15
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924618_620316911.0RepeatNote=1
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924640_642316911.0RepeatNote=2
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924645_647316911.0RepeatNote=3
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924650_652316911.0RepeatNote=4
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924656_658316911.0RepeatNote=5
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924661_663316911.0RepeatNote=6
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924667_669316911.0RepeatNote=7
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924685_687316911.0RepeatNote=8
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924690_692316911.0RepeatNote=9
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924709_711316911.0RepeatNote=10
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924728_730316911.0RepeatNote=11
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924754_756316911.0RepeatNote=12
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924806_808316911.0RepeatNote=13
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924812_814316911.0RepeatNote=14
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924833_835316911.0RepeatNote=15
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922618_620316755.0RepeatNote=1
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922640_642316755.0RepeatNote=2
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922645_647316755.0RepeatNote=3
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922650_652316755.0RepeatNote=4
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922656_658316755.0RepeatNote=5
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922661_663316755.0RepeatNote=6
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922667_669316755.0RepeatNote=7
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922685_687316755.0RepeatNote=8
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922690_692316755.0RepeatNote=9
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922709_711316755.0RepeatNote=10
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922728_730316755.0RepeatNote=11
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922754_756316755.0RepeatNote=12
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922806_808316755.0RepeatNote=13
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922812_814316755.0RepeatNote=14
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922833_835316755.0RepeatNote=15
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916618_620316602.0RepeatNote=1
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916640_642316602.0RepeatNote=2
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916645_647316602.0RepeatNote=3
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916650_652316602.0RepeatNote=4
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916656_658316602.0RepeatNote=5
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916661_663316602.0RepeatNote=6
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916667_669316602.0RepeatNote=7
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916685_687316602.0RepeatNote=8
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916690_692316602.0RepeatNote=9
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916709_711316602.0RepeatNote=10
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916728_730316602.0RepeatNote=11
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916754_756316602.0RepeatNote=12
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916806_808316602.0RepeatNote=13
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916812_814316602.0RepeatNote=14
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916833_835316602.0RepeatNote=15

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000431408-45111_13196105.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000431408-45133_15396105.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000431408-45165_18496105.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000431408-45188_20796105.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000431408-45222_24296105.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000431408-45252_27496105.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000431408-45282_30396105.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000431408-45312_33296105.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000595753-46252_274252411.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000595753-46282_303252411.0TransmembraneHelical
HgeneSLC35E1chr19:16677343chr19:16528915ENST00000595753-46312_332252411.0TransmembraneHelical
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923172_184316865.0Calcium bindingOntology_term=ECO:0000255
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924172_184316911.0Calcium bindingOntology_term=ECO:0000255
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922172_184316755.0Calcium bindingOntology_term=ECO:0000255
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916172_184316602.0Calcium bindingOntology_term=ECO:0000255
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923127_215316865.0DomainEH 2
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923159_194316865.0DomainEF-hand
TgeneEPS15L1chr19:16677343chr19:16528915ENST0000024807092315_104316865.0DomainEH 1
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000248070923275_365316865.0DomainEH 3
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924127_215316911.0DomainEH 2
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924159_194316911.0DomainEF-hand
TgeneEPS15L1chr19:16677343chr19:16528915ENST0000045514092415_104316911.0DomainEH 1
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000455140924275_365316911.0DomainEH 3
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922127_215316755.0DomainEH 2
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922159_194316755.0DomainEF-hand
TgeneEPS15L1chr19:16677343chr19:16528915ENST0000053575392215_104316755.0DomainEH 1
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000535753922275_365316755.0DomainEH 3
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916127_215316602.0DomainEH 2
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916159_194316602.0DomainEF-hand
TgeneEPS15L1chr19:16677343chr19:16528915ENST0000059793791615_104316602.0DomainEH 1
TgeneEPS15L1chr19:16677343chr19:16528915ENST00000597937916275_365316602.0DomainEH 3


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Fusion Gene Sequence for SLC35E1-EPS15L1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>82968_82968_1_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000248070_length(transcript)=2402nt_BP=568nt
GTGCCACATCCTGGCTCTGTGCGCTGGGCTCCCGCCGCTGCTGCGCGCCTGGCGCGTGCCCCCCGCGCCGCCCGTCTCGGGCCCCGGACC
CAGTCCGCATCCGTCGTCCGGCCCGCTGCTGCCGCCGCGCTTCTACCCGCGCTACGTGCTACCGCTCGCCTTCGGCAAGTACTTCGCGTC
CGTGTCAGCGCACGTCAGCATCTGGAAGGTGCCCGTGTCCTATGCACACACCGTCAAGGCCACCATGCCCATCTGGGTGGTCCTCCTGTC
CCGGATCATTATGAAGGAGAAGCAGAGCACCAAGGTATACTTGTCACTCATCCCCATCATCAGCGGTGTCCTGCTGGCCACCGTCACCGA
GTTGTCTTTTGACATGTGGGGACTCGTCAGCGCCCTCGCCGCCACGCTGTGCTTCTCGCTTCAGAACATTTTCTCCAAAAAGGTCTTGCG
AGATTCACGGATCCACCATCTCCGGCTGCTCAACATCCTGGGCTGCCACGCCGTCTTCTTTATGATCCCCACCTGGGTTCTGGTGGACCT
CTCGGCTTTCCTGGTCAGCAGCGACTTGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGT
ATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCG
GCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAA
GAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACC
TAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCA
AGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGG
AATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGA
GCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTT
CCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCG
ACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTAT
TTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCA
AAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACC
CATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCT
TACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAG
ATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGCCCCCACCTTCTGGCCCTTTCACCT
CCTCCTTGGGAGGGGCAGGATTCTCAGATGACCCCTTTAAAAGTAAACAGGACACTCCTGCTCTGCCTCCGAAGAAACCTGCTCCTCCAC
GGCCTAAACCGCCCAGCGGTAAAAGTACACCTGTAAGCCAGCTTGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCACTCG
GGGCTGACAGCGGCGACCCGTTCCAAAGTAAAAAGGGGTTTGGGGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCAGCTA
AACCTTCTAAGGCCTCTGCCTCGGGCTTTGCAGACTTCACCTCTGTAAGTTGAGTCCTCCGCCTCCGGGCCACCCCACTCCCTTCCGCTT
GCAGCTTCCCTGGGATTTTTGTCTCCTTTTAAAGGCAAACCTCCCAGCTTCTTTAGCCTCTTGGTACCTCACACTCTCTGTCCCTCGCGT

>82968_82968_1_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000248070_length(amino acids)=546AA_BP=1
MADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIR
EKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDL
NRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSL
AERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDDFF
KKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKPPPSGPFTSSLGGAGFSDD
PFKSKQDTPALPPKKPAPPRPKPPSGKSTPVSQLGSADFPEAPDPFQPLGADSGDPFQSKKGFGDPFSGKDPFVPSSAAKPSKASASGFA

--------------------------------------------------------------
>82968_82968_2_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000455140_length(transcript)=2817nt_BP=568nt
GTGCCACATCCTGGCTCTGTGCGCTGGGCTCCCGCCGCTGCTGCGCGCCTGGCGCGTGCCCCCCGCGCCGCCCGTCTCGGGCCCCGGACC
CAGTCCGCATCCGTCGTCCGGCCCGCTGCTGCCGCCGCGCTTCTACCCGCGCTACGTGCTACCGCTCGCCTTCGGCAAGTACTTCGCGTC
CGTGTCAGCGCACGTCAGCATCTGGAAGGTGCCCGTGTCCTATGCACACACCGTCAAGGCCACCATGCCCATCTGGGTGGTCCTCCTGTC
CCGGATCATTATGAAGGAGAAGCAGAGCACCAAGGTATACTTGTCACTCATCCCCATCATCAGCGGTGTCCTGCTGGCCACCGTCACCGA
GTTGTCTTTTGACATGTGGGGACTCGTCAGCGCCCTCGCCGCCACGCTGTGCTTCTCGCTTCAGAACATTTTCTCCAAAAAGGTCTTGCG
AGATTCACGGATCCACCATCTCCGGCTGCTCAACATCCTGGGCTGCCACGCCGTCTTCTTTATGATCCCCACCTGGGTTCTGGTGGACCT
CTCGGCTTTCCTGGTCAGCAGCGACTTGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGT
ATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCG
GCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAA
GAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACC
TAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCA
AGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGG
AATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGA
GCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTT
CCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCG
ACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTAT
TTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCA
AAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACC
CATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCT
TACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAG
ATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGCCCCCACCTTCTGGCCCTTTCACCT
CCTCCTTGGGAGGGGCAGGATTCTCAGATGACCCCTTTAAAAGTAAACAGGACACTCCTGCTCTGCCTCCGAAGAAACCTGCTCCTCCAC
GGCCTAAACCGCCCAGCGGTAAAAGTACACCTGTAAGCCAGCTTGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCACTCG
GGGCTGACAGCGGCGACCCGTTCCAAAGTAAAAAGGGGTTTGGGGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCAGCTA
AACCTTCTAAGGCCTCTGCCTCGGGCTTTGCAGACTTCACCTCTTTTGGCAATGAGGAGCAGCAGCTGGCGTGGGCCAAGCGGGAGAGCG
AGAAGGCGGAACAGGAGAGGCTGGCGCGGCTGCGGCGGCAGGAGCAGGAGGACCTGGAACTGGCCATCGCGCTCAGCAAGGCTGACATGC
CTGCCGCCTAGGCGAGGGCCGTGTGTAGGCGGGACAGGGCACGGGCGGGTTCCAGAGAGGGGGCAGTGCAGATGTCTATATATACACACA
CACACCGTCGCCACCGTACTCCAAGGACCGGGACTCGGGGGCTTGTTCAGGGTGAGCAGACTCGGCTGCAAGACCTGGAAAGGTCACATC
TCCTGGGGAAGCCCTTACAGAGGCCTTGGCCACCACTTCTGCAGGTCCGTCTCTCCACTGTGCCATCCCCCCCGGGGCTGACTGCCTCCC
GCTCTTCCTCTGGGGACGAACACACAGCGGTCAGTCGAGGAGAGGAAGCACCCAGGGCTTCCCCGCCTCCTCCCTACTCATAGCTGCAGA
CATCCCCACCCGCCCTCCCACGCATCAGTCAGACACTCCCCCAGTGGTGTATGCACTCGTTGTATAAAATGAAGTTTGAATGATTAATAT

>82968_82968_2_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000455140_length(amino acids)=592AA_BP=1
MADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIR
EKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDL
NRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSL
AERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDDFF
KKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKPPPSGPFTSSLGGAGFSDD
PFKSKQDTPALPPKKPAPPRPKPPSGKSTPVSQLGSADFPEAPDPFQPLGADSGDPFQSKKGFGDPFSGKDPFVPSSAAKPSKASASGFA

--------------------------------------------------------------
>82968_82968_3_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000535753_length(transcript)=2253nt_BP=568nt
GTGCCACATCCTGGCTCTGTGCGCTGGGCTCCCGCCGCTGCTGCGCGCCTGGCGCGTGCCCCCCGCGCCGCCCGTCTCGGGCCCCGGACC
CAGTCCGCATCCGTCGTCCGGCCCGCTGCTGCCGCCGCGCTTCTACCCGCGCTACGTGCTACCGCTCGCCTTCGGCAAGTACTTCGCGTC
CGTGTCAGCGCACGTCAGCATCTGGAAGGTGCCCGTGTCCTATGCACACACCGTCAAGGCCACCATGCCCATCTGGGTGGTCCTCCTGTC
CCGGATCATTATGAAGGAGAAGCAGAGCACCAAGGTATACTTGTCACTCATCCCCATCATCAGCGGTGTCCTGCTGGCCACCGTCACCGA
GTTGTCTTTTGACATGTGGGGACTCGTCAGCGCCCTCGCCGCCACGCTGTGCTTCTCGCTTCAGAACATTTTCTCCAAAAAGGTCTTGCG
AGATTCACGGATCCACCATCTCCGGCTGCTCAACATCCTGGGCTGCCACGCCGTCTTCTTTATGATCCCCACCTGGGTTCTGGTGGACCT
CTCGGCTTTCCTGGTCAGCAGCGACTTGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGT
ATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCG
GCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAA
GAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACC
TAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCA
AGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGG
AATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGA
GCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTT
CCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCG
ACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTAT
TTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCA
AAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACC
CATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCT
TACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAG
ATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGTAAAAGTACACCTGTAAGCCAGCT
TGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCACTCGGGGCTGACAGCGGCGACCCGTTCCAAAGTAAAAAGGGGTTTGG
GGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCAGCTAAACCTTCTAAGGCCTCTGCCTCGGGCTTTGCAGACTTCACCTC
TGTAAGTTGAGTCCTCCGCCTCCGGGCCACCCCACTCCCTTCCGCTTGCAGCTTCCCTGGGATTTTTGTCTCCTTTTAAAGGCAAACCTC
CCAGCTTCTTTAGCCTCTTGGTACCTCACACTCTCTGTCCCTCGCGTTATTTATTCTACACTGCCACTTCTGTAAGAAAAACAGTTTCTC

>82968_82968_3_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000535753_length(amino acids)=436AA_BP=1
MADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIR
EKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDL
NRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSL
AERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDDFF

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>82968_82968_4_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000594975_length(transcript)=1967nt_BP=568nt
GTGCCACATCCTGGCTCTGTGCGCTGGGCTCCCGCCGCTGCTGCGCGCCTGGCGCGTGCCCCCCGCGCCGCCCGTCTCGGGCCCCGGACC
CAGTCCGCATCCGTCGTCCGGCCCGCTGCTGCCGCCGCGCTTCTACCCGCGCTACGTGCTACCGCTCGCCTTCGGCAAGTACTTCGCGTC
CGTGTCAGCGCACGTCAGCATCTGGAAGGTGCCCGTGTCCTATGCACACACCGTCAAGGCCACCATGCCCATCTGGGTGGTCCTCCTGTC
CCGGATCATTATGAAGGAGAAGCAGAGCACCAAGGTATACTTGTCACTCATCCCCATCATCAGCGGTGTCCTGCTGGCCACCGTCACCGA
GTTGTCTTTTGACATGTGGGGACTCGTCAGCGCCCTCGCCGCCACGCTGTGCTTCTCGCTTCAGAACATTTTCTCCAAAAAGGTCTTGCG
AGATTCACGGATCCACCATCTCCGGCTGCTCAACATCCTGGGCTGCCACGCCGTCTTCTTTATGATCCCCACCTGGGTTCTGGTGGACCT
CTCGGCTTTCCTGGTCAGCAGCGACTTGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGT
ATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCG
GCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAA
GAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACC
TAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCA
AGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGG
AATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGA
GCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTT
CCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCG
ACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGATGATCCTTTCAAAAATAAAGCCT
TGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACC
CCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAA
GTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACC
CTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAA
CCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGTAAAAGTACACCTGTAAG

>82968_82968_4_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000594975_length(amino acids)=438AA_BP=1
MADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIR
EKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDL
NRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSL
AERGSFGAMVKDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDD

--------------------------------------------------------------
>82968_82968_5_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000597937_length(transcript)=3099nt_BP=568nt
GTGCCACATCCTGGCTCTGTGCGCTGGGCTCCCGCCGCTGCTGCGCGCCTGGCGCGTGCCCCCCGCGCCGCCCGTCTCGGGCCCCGGACC
CAGTCCGCATCCGTCGTCCGGCCCGCTGCTGCCGCCGCGCTTCTACCCGCGCTACGTGCTACCGCTCGCCTTCGGCAAGTACTTCGCGTC
CGTGTCAGCGCACGTCAGCATCTGGAAGGTGCCCGTGTCCTATGCACACACCGTCAAGGCCACCATGCCCATCTGGGTGGTCCTCCTGTC
CCGGATCATTATGAAGGAGAAGCAGAGCACCAAGGTATACTTGTCACTCATCCCCATCATCAGCGGTGTCCTGCTGGCCACCGTCACCGA
GTTGTCTTTTGACATGTGGGGACTCGTCAGCGCCCTCGCCGCCACGCTGTGCTTCTCGCTTCAGAACATTTTCTCCAAAAAGGTCTTGCG
AGATTCACGGATCCACCATCTCCGGCTGCTCAACATCCTGGGCTGCCACGCCGTCTTCTTTATGATCCCCACCTGGGTTCTGGTGGACCT
CTCGGCTTTCCTGGTCAGCAGCGACTTGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGT
ATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCG
GCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAA
GAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACC
TAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCA
AGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGG
AATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGA
GCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTT
CCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCG
ACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGTTGAATAAACGTATTACAGTATGG
GGCTCTGGTCCCCTGGTGTGACAGCAGAACATCCCACCCGCCAGATCTGTTCATGGCCAACGTTGGTTCCAGCCAAGTGCAGGCGGCTGT
CTGTTGTTTTTGCTGCCACTTTGCGCGTTCACACCAGGCCTTGCAGCCTGGCACAGGTGGCCATGCTGAATCCTGGCTTCCAGAACAAAG
TCCAAGATAGGCCTGGATCCTTTCAGAACCTGTTTTGAATGCCCTCCATCTCTGCGGAAGTATTTACATTGGGCCAACCACCCAAGTTCA
GAGGGCTTCTCAAACTTAACCAAAATTGGATCAGTTTCTGCTCATTGTGGAAACCCCACATTCTACTAATCAGGGGGCAGGGGACATCTG
AGGGGCATGTGTCTATGTGTATGTGTGTTTCCACAAGGAACACCTTGAAAAGCAAATGTGTTGCTAAAGATGAGGAAGTAATGGCAAGCA
GCGCCCCAGGGTGTTGCTCTTTCAAGTAAGAATTGGCCTCTCCTGAAATTTTGGTTATGTTTAAAAACCTCTGCACTTTACTCTGACCTC
ATGACCCTGGAGTTGTGATCAGGCCTGGGGCAGGGGACTGTCGGCCCCTTACATTTTTGAGAGCTCTTGAGCCCCTGATACCAAGACAGG
TGTGACCTTTTCCTTAGGTGGTCACATCCCCCCTGTTCACACCAGAGTCTGCCCCTGCAGCCTCGAACCTGGGGACATGTAGTTTCCCAT
TTCGTCTTGGTGCTGTTCCGGGAGCGGATGGGCCGGGCCGCGCATGTCTGGATGTTTCCTTGGTGCTCTGCTGCCTCCAGCAGCTCTCTC
CGTGCTGCCACCCTCTCTCCCAGGGCTCCTCCCTGGAGCCCTTCTGCTCCTGGGCCTCTGTACGTCATGGATTCCTCTTCCTCCCTGGAA
TAAGAGTGAGCGCTCGTGCTCTCTAAACACCACACTTGCCTCTTTATGTTCAATGCTTGATGTGTTTCTTTTCTCAGCAGCCAAGTCCTC
AGTCCCAAGGATTTATGGGGAAGCACACGCGTCCCCTGGGCTGCTGGGAAGGCACTGCTGGCGAGCTCATCTGTCTCTTGTGTCTGGCCC
CCGCTGGGTGCACCGCCTCCCTCTTTCCTCCCATACTCTCTTTTCTCGTGGACTCGTAATGAGGTGGTTTCCATAGCCGCCCCCGGGCCC
GTCATCATCAGCTTTATCGTCTAAATTTAAACGATGAGCATTCATCCTTCATGAGTTACGAGAAGCCAGAACTCCTCGCTTTGCTCCCTG
GCTGTTCTTGGCGTGTGTGTTTCCGTCTCACAACCCGGCTCCTACTTTCCCCATCTGGCATTGTCCCCTGGCACCGCTTTTGGCTTGTCC
TGCTCAGTCTTCGTTCAGGGAACAGCTTCCTCTTAAATGTCCCTTTTGCAGGTTTTTAGAAACCGGTTTTCTTGGATAAAAGTTGGCAGT
GAAGTGGCAGTTTGCAAGTGGCCAGTGATTCCCCCAACTCCAAAGACAGATTTTTACCTTTCTGGTTATTTTTGTTCATCTTTTGGGCAG
GGCAAAGGTTACCTGAGACACAATTACTTTGGGAATGTAGATTAAGATACGTTACATGGAAACTTGCAACTGGCATCCGAAAGAAAAACT

>82968_82968_5_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000597937_length(amino acids)=283AA_BP=1
MADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIR
EKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDL
NRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSL

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>82968_82968_6_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000602009_length(transcript)=3099nt_BP=568nt
GTGCCACATCCTGGCTCTGTGCGCTGGGCTCCCGCCGCTGCTGCGCGCCTGGCGCGTGCCCCCCGCGCCGCCCGTCTCGGGCCCCGGACC
CAGTCCGCATCCGTCGTCCGGCCCGCTGCTGCCGCCGCGCTTCTACCCGCGCTACGTGCTACCGCTCGCCTTCGGCAAGTACTTCGCGTC
CGTGTCAGCGCACGTCAGCATCTGGAAGGTGCCCGTGTCCTATGCACACACCGTCAAGGCCACCATGCCCATCTGGGTGGTCCTCCTGTC
CCGGATCATTATGAAGGAGAAGCAGAGCACCAAGGTATACTTGTCACTCATCCCCATCATCAGCGGTGTCCTGCTGGCCACCGTCACCGA
GTTGTCTTTTGACATGTGGGGACTCGTCAGCGCCCTCGCCGCCACGCTGTGCTTCTCGCTTCAGAACATTTTCTCCAAAAAGGTCTTGCG
AGATTCACGGATCCACCATCTCCGGCTGCTCAACATCCTGGGCTGCCACGCCGTCTTCTTTATGATCCCCACCTGGGTTCTGGTGGACCT
CTCGGCTTTCCTGGTCAGCAGCGACTTGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGT
ATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCG
GCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAA
GAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACC
TAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCA
AGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGG
AATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGA
GCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTT
CCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCG
ACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGTTGAATAAACGTATTACAGTATGG
GGCTCTGGTCCCCTGGTGTGACAGCAGAACATCCCACCCGCCAGATCTGTTCATGGCCAACGTTGGTTCCAGCCAAGTGCAGGCGGCTGT
CTGTTGTTTTTGCTGCCACTTTGCGCGTTCACACCAGGCCTTGCAGCCTGGCACAGGTGGCCATGCTGAATCCTGGCTTCCAGAACAAAG
TCCAAGATAGGCCTGGATCCTTTCAGAACCTGTTTTGAATGCCCTCCATCTCTGCGGAAGTATTTACATTGGGCCAACCACCCAAGTTCA
GAGGGCTTCTCAAACTTAACCAAAATTGGATCAGTTTCTGCTCATTGTGGAAACCCCACATTCTACTAATCAGGGGGCAGGGGACATCTG
AGGGGCATGTGTCTATGTGTATGTGTGTTTCCACAAGGAACACCTTGAAAAGCAAATGTGTTGCTAAAGATGAGGAAGTAATGGCAAGCA
GCGCCCCAGGGTGTTGCTCTTTCAAGTAAGAATTGGCCTCTCCTGAAATTTTGGTTATGTTTAAAAACCTCTGCACTTTACTCTGACCTC
ATGACCCTGGAGTTGTGATCAGGCCTGGGGCAGGGGACTGTCGGCCCCTTACATTTTTGAGAGCTCTTGAGCCCCTGATACCAAGACAGG
TGTGACCTTTTCCTTAGGTGGTCACATCCCCCCTGTTCACACCAGAGTCTGCCCCTGCAGCCTCGAACCTGGGGACATGTAGTTTCCCAT
TTCGTCTTGGTGCTGTTCCGGGAGCGGATGGGCCGGGCCGCGCATGTCTGGATGTTTCCTTGGTGCTCTGCTGCCTCCAGCAGCTCTCTC
CGTGCTGCCACCCTCTCTCCCAGGGCTCCTCCCTGGAGCCCTTCTGCTCCTGGGCCTCTGTACGTCATGGATTCCTCTTCCTCCCTGGAA
TAAGAGTGAGCGCTCGTGCTCTCTAAACACCACACTTGCCTCTTTATGTTCAATGCTTGATGTGTTTCTTTTCTCAGCAGCCAAGTCCTC
AGTCCCAAGGATTTATGGGGAAGCACACGCGTCCCCTGGGCTGCTGGGAAGGCACTGCTGGCGAGCTCATCTGTCTCTTGTGTCTGGCCC
CCGCTGGGTGCACCGCCTCCCTCTTTCCTCCCATACTCTCTTTTCTCGTGGACTCGTAATGAGGTGGTTTCCATAGCCGCCCCCGGGCCC
GTCATCATCAGCTTTATCGTCTAAATTTAAACGATGAGCATTCATCCTTCATGAGTTACGAGAAGCCAGAACTCCTCGCTTTGCTCCCTG
GCTGTTCTTGGCGTGTGTGTTTCCGTCTCACAACCCGGCTCCTACTTTCCCCATCTGGCATTGTCCCCTGGCACCGCTTTTGGCTTGTCC
TGCTCAGTCTTCGTTCAGGGAACAGCTTCCTCTTAAATGTCCCTTTTGCAGGTTTTTAGAAACCGGTTTTCTTGGATAAAAGTTGGCAGT
GAAGTGGCAGTTTGCAAGTGGCCAGTGATTCCCCCAACTCCAAAGACAGATTTTTACCTTTCTGGTTATTTTTGTTCATCTTTTGGGCAG
GGCAAAGGTTACCTGAGACACAATTACTTTGGGAATGTAGATTAAGATACGTTACATGGAAACTTGCAACTGGCATCCGAAAGAAAAACT

>82968_82968_6_SLC35E1-EPS15L1_SLC35E1_chr19_16677343_ENST00000431408_EPS15L1_chr19_16528915_ENST00000602009_length(amino acids)=283AA_BP=1
MADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIR
EKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDL
NRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSL

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Fusion Gene PPI Analysis for SLC35E1-EPS15L1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneEPS15L1chr19:16677343chr19:16528915ENST0000024807092315_368316.6666666666667865.0DAB2
TgeneEPS15L1chr19:16677343chr19:16528915ENST0000045514092415_368316.6666666666667911.0DAB2
TgeneEPS15L1chr19:16677343chr19:16528915ENST0000053575392215_368316.6666666666667755.0DAB2
TgeneEPS15L1chr19:16677343chr19:16528915ENST0000059793791615_368316.6666666666667602.0DAB2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SLC35E1-EPS15L1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SLC35E1-EPS15L1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource