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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SLC37A1-PCNT (FusionGDB2 ID:83054)

Fusion Gene Summary for SLC37A1-PCNT

Fusion gene summary

Fusion gene information	Fusion gene name: SLC37A1-PCNT
	Fusion gene ID: 83054
		Hgene	Tgene
	Gene symbol	SLC37A1	PCNT
	Gene ID	54020	5116
	Gene name	solute carrier family 37 member 1	pericentrin
	Synonyms	G3PP	KEN\|MOPD2\|PCN\|PCNT2\|PCNTB\|PCTN2\|SCKL4
	Cytomap	21q22.3	21q22.3
	Type of gene	protein-coding	protein-coding
	Description	glucose-6-phosphate exchanger SLC37A1G-3-P permeaseG-3-P transporterglycerol-3-phosphate permeaseglycerol-3-phosphate transportersolute carrier family 37 (glucose-6-phosphate transporter), member 1solute carrier family 37 (glycerol-3-phosphate trans	pericentrinkendrinpericentrin-2pericentrin-380pericentrin-B
	Modification date	20200313	20200320
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000352133, ENST00000398341, ENST00000454800,	ENST00000480896, ENST00000359568,
Fusion gene scores	* DoF score	7 X 6 X 3=126	11 X 12 X 5=660
	# samples	8	11
	** MAII score	log2(8/126*10)=-0.655351828612554 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(11/660*10)=-2.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SLC37A1 [Title/Abstract] AND PCNT [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SLC37A1(43987168)-PCNT(47831103), # samples:3
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	SLC37A1	GO:0015760	glucose-6-phosphate transport	21949678
Hgene	SLC37A1	GO:0035435	phosphate ion transmembrane transport	21949678
Tgene	PCNT	GO:0060271	cilium assembly	15337773

Fusion gene breakpoints across SLC37A1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PCNT (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-A2-A3XY-01A	SLC37A1	chr21	43987168	-	PCNT	chr21	47831103	+
ChimerDB4	BRCA	TCGA-A2-A3XY-01A	SLC37A1	chr21	43987168	+	PCNT	chr21	47831103	+

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Fusion Gene ORF analysis for SLC37A1-PCNT

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000352133	ENST00000480896	SLC37A1	chr21	43987168	+	PCNT	chr21	47831103	+
5CDS-3UTR	ENST00000398341	ENST00000480896	SLC37A1	chr21	43987168	+	PCNT	chr21	47831103	+
In-frame	ENST00000352133	ENST00000359568	SLC37A1	chr21	43987168	+	PCNT	chr21	47831103	+
In-frame	ENST00000398341	ENST00000359568	SLC37A1	chr21	43987168	+	PCNT	chr21	47831103	+
intron-3CDS	ENST00000454800	ENST00000359568	SLC37A1	chr21	43987168	+	PCNT	chr21	47831103	+
intron-3UTR	ENST00000454800	ENST00000480896	SLC37A1	chr21	43987168	+	PCNT	chr21	47831103	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

ENST00000398341

SLC37A1

chr21

43987168

ENST00000359568

PCNT

chr21

47831103

7094

1756

412

6651

2079

ENST00000352133

SLC37A1

chr21

43987168

ENST00000359568

PCNT

chr21

47831103

7664

2326

982

7221

2079

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000398341	ENST00000359568	SLC37A1	chr21	43987168	+	PCNT	chr21	47831103	+	0.008315461	0.99168456
ENST00000352133	ENST00000359568	SLC37A1	chr21	43987168	+	PCNT	chr21	47831103	+	0.013225758	0.9867742

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Fusion Genomic Features for SLC37A1-PCNT

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
SLC37A1	chr21	43987168	+	PCNT	chr21	47831102	+	0.001196858	0.99880314
SLC37A1	chr21	43987168	+	PCNT	chr21	47831102	+	0.001196858	0.99880314

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SLC37A1-PCNT

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:43987168/chr21:47831103)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

100_120

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

129_149

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

157_177

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

18_38

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

222_242

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

304_324

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

334_354

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

366_386

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

394_414

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

423_443

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

100_120

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

129_149

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

157_177

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

18_38

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

222_242

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

304_324

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

334_354

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

366_386

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

394_414

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

423_443

448

534.0

Transmembrane

Helical

Tgene

PCNT

chr21:43987168

chr21:47831103

ENST00000359568

2064_2082

1705

3337.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PCNT

chr21:43987168

chr21:47831103

ENST00000359568

2536_3086

1705

3337.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PCNT

chr21:43987168

chr21:47831103

ENST00000359568

3195_3208

1705

3337.0

Region

Note=Calmodulin-binding

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

466_486

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000352133

490_510

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

466_486

448

534.0

Transmembrane

Helical

Hgene

SLC37A1

chr21:43987168

chr21:47831103

ENST00000398341

490_510

448

534.0

Transmembrane

Helical

Tgene

PCNT

chr21:43987168

chr21:47831103

ENST00000359568

1010_1146

1705

3337.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PCNT

chr21:43987168

chr21:47831103

ENST00000359568

1299_1949

1705

3337.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PCNT

chr21:43987168

chr21:47831103

ENST00000359568

258_553

1705

3337.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PCNT

chr21:43987168

chr21:47831103

ENST00000359568

675_835

1705

3337.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PCNT

chr21:43987168

chr21:47831103

ENST00000359568

214_795

1705

3337.0

Compositional bias

Note=Glu-rich

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Fusion Gene Sequence for SLC37A1-PCNT

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>83054_83054_1_SLC37A1-PCNT_SLC37A1_chr21_43987168_ENST00000352133_PCNT_chr21_47831103_ENST00000359568_length(transcript)=7664nt_BP=2326nt
CGGCGGCGCAGGTGAGGCGCGGGGCCGGGGCCGGACCGGGAGGCGGGGACCCCCCGCCCCCCCGCCCGCACCTGCGGGGCAGCCGGCGCT
CAGGCGCCGCAGCCGCTCAGCACCTGCGGCGCCCTCAGGGAGCCGGGCGCGGGGCCCTGCGCACTCGGAGCTCGGCTCCTCTCCTTCCTT
TTCTTTTTTTTCGGGGGGAGGTGGGGGCTGGTTTGGATGTTTTCCGAGAGCCGGGGACGGTCTCAAGCTATTTTCGCGGAGGGAAGTCTT
TGAAATACGACATCTAGAAGAGTGGCCCTCGGCGACAATGCCGGGCGTTCCCGGACCGGGGCAACGCTGGGATTCCGGGGAAGTGGAGGC
AGAGGGAGCGGGCACGGGGCCGGCAGCCGCTCCACGGAGTCCCCGGCAGGGGCGAGCTTAGCTGTCCAGCCGGGTCCCCTGCCCACCCCG
GCCCGGGCCGCGGTGACAGCTGAGGGTCCAGAGAGCCGGCAGGAGGGGACCCTGCGCATTGTCTGCCGCGATGGGGACGTGGGCGTGCCC
GCGGAATTCACCTCCTCCGGGGACCAGCCGCCCAGGGAGGAGCCGGCACAGAACGCTGGCTCGGAGCGCCGGCACCCTGGGCCTTTGCGT
TGTTTGTCGGCTGAGCAGCTGGTTCCCGGAGCCCGTGGGCCTCCTGGCCAATGCGAGTGACAGCGACCTTCTGGGTTTATAATAAAGGGC
TTGACGCGCCGGAAAGTCCCCTCGCCGCTGGCCACCAGCCTTCCAGCCCTTACGGCCCACGCCGTAATCCTGGTGACCGAGAAGAGAGCA
GAGCCACTGCCAGAAGGAAGGGGACAAGACCCAGCAGGACACCTTCTTTCCACGCTTTCCAGCCTGTGGGAGCGGCAGGGGCAACAGAGA
GAGGATCTGGAGCCAGGATTAATGACTCATTTATGAAGCATCTTATTCTGCGACCGAGGCTCAGTGGTCAGTGGCGACGTAAATGGCTCG
ACTCCCCGCTGGCATTCGCTTCATCATCTCATTCTCCAGGGATCAGTGGTACAGAGCCTTCATTTTTATTTTGACATTTCTGCTGTATGC
AAGTTTTCACTTATCTCGAAAGCCTATCAGCATAGTTAAGGGTGAGCTCCACAAGTACTGCACTGCTTGGGATGAAGCTGACGTCAGGTT
CAGCAGCCAGAACAGGAAGTCTGGGTCCGCTGCCCCCCACCAGCTCCCTGACAATGAGACCGACTGTGGCTGGGCACCGTTTGATAAGAA
CAACTATCAGCAGCTGCTTGGGGCCCTGGACTACTCCTTCCTGTGCGCCTATGCCGTGGGGATGTACCTCAGTGGCATCATTGGGGAGCG
CCTGCCGATTAGGTATTACCTAACTTTCGGGATGCTCGCCAGCGGAGCCTTCACCGCCCTGTTCGGCTTAGGGTATTTCTACAACATCCA
CAGTTTCGGATTCTACGTGGTAACTCAGGTCATCAACGGGCTGGTGCAGACCACCGGCTGGCCCAGCGTCGTCACCTGCCTCGGCAACTG
GTTTGGAAAAGGAAGGAGAGGTTTGATTATGGGGGTCTGGAACTCCCACACCTCCGTGGGCAACATCTTGGGGTCATTGATCGCTGGCTA
CTGGGTGTCCACATGCTGGGGCCTGTCCTTCGTCGTGCCTGGAGCCATCGTGGCAGCCATGGGGATAGTGTGCTTTCTCTTCCTCATTGA
ACATCCGAACGACGTCAGGTGCTCCTCCACCCTGGTGACGCACTCAAAAGGCTATGAGAATGGTACAAACAGATTGAGACTCCAGAAGCA
AATCTTGAAGAGCGAAAAGAACAAGCCTCTGGACCCAGAGATGCAGTGCCTGCTGCTCTCAGATGGGAAGGGCTCCATCCACCCGAACCA
CGTCGTCATTCTCCCCGGGGACGGTGGGAGTGGCACGGCCGCCATCAGCTTCACAGGGGCCTTGAAAATTCCAGGCGTGATAGAGTTCTC
ACTGTGTCTGCTGTTTGCCAAGCTGGTCAGCTATACTTTCCTCTTCTGGCTGCCCCTGTACATCACGAATGTGGATCACCTTGATGCCAA
AAAGGCGGGGGAGCTCTCCACCCTGTTTGACGTGGGCGGAATCTTTGGTGGGATCCTGGCAGGTGTGATCTCAGACCGACTGGAGAAAAG
GGCCTCCACCTGCGGCCTGATGCTGCTGCTCGCGGCCCCCACGCTCTACATCTTCTCCACCGTCAGCAAGATGGGGCTTGAGGCCACCAT
CGCCATGCTGCTGCTCAGCGGAGCCCTGGTCAGTGGGCCCTACACACTCATCACCACCGCCGTCTCCGCCGACCTGGTCATATATACCAG
AAGTTCTGAGATTGAAGAGCTGAAAGCCACTATTGAAAATCTGCAAGAGAATCAGAAACGATTACAAAAGGAGAAAGCAGAGGAAATTGA
ACAACTCCATGAAGTCATTGAGAAGCTGCAGCACGAGCTGTCCCTCATGGGGCCTGTGGTGCACGAAGTCAGCGACAGTCAGGCTGGCAG
TCTGCAGAGCGAGCTGCTCTGCTCCCAGGCCGGGGGCCCTCGTGGGCAGGCCCTACAGGGCGAGCTCGAGGCTGCGCTGGAAGCCAAGGA
GGCCCTGAGCCGGCTGCTGGCTGACCAGGAGCGCAGGCACAGCCAGGCCCTGGAGGCCCTGCAGCAGCGCCTCCAGGGCGCAGAGGAGGC
TGCGGAGCTACAGCTGGCTGAGCTGGAGCGCAATGTAGCCCTCAGGGAGGCTGAGGTCGAAGACATGGCCTCCCGGATCCAGGAGTTCGA
AGCGGCCCTGAAAGCAAAGGAAGCGACGATTGCCGAGAGAAATTTAGAAATCGACGCTCTGAACCAGCGGAAGGCGGCCCACTCTGCCGA
GCTGGAGGCCGTCCTGTTGGCCTTGGCCCGCATCCGCCGCGCCCTGGAGCAGCAGCCCCTGGCAGCCGGGGCGGCGCCTCCCGAGCTGCA
GTGGCTCCGAGCGCAGTGTGCCCGCCTCAGCCGCCAGCTGCAGGTGCTGCACCAGCGGTTCCTGAGGTGCCAGGTGGAGCTGGACAGGCG
GCAGGCCCGCAGAGCCACAGCTCACACACGGGTGCCCGGGGCCCACCCACAGCCTCGCATGGATGGTGGCGCCAAGGCCCAGGTCACCGG
CGACGTGGAGGCCTCCCATGATGCTGCTTTGGAGCCGGTTGTCCCTGACCCACAGGGTGATCTGCAGCCTGTCCTGGTGACGTTGAAGGA
TGCACCTCTCTGCAAGCAAGAAGGCGTGATGTCAGTGCTCACCGTCTGCCAGAGGCAGCTGCAGTCGGAGCTGCTCTTGGTGAAAAATGA
AATGCGCCTGAGTCTGGAGGACGGCGGCAAGGGTAAAGAAAAAGTACTGGAAGATTGTCAGCTGCCGAAGGTCGATCTCGTAGCTCAGGT
GAAACAGCTTCAGGAAAAACTGAACCGTTTGCTGTATTCCATGACCTTCCAGAATGTGGATGCTGCCGACACCAAATCTCTGTGGCCCAT
GGCCTCAGCACACCTGTTGGAGAGCAGCTGGAGTGATGATTCCTGTGACGGAGAAGAGCCTGACATATCACCCCACATAGACACATGTGA
TGCCAATACAGCCACGGGGGGTGTAACTGATGTTATCAAAAATCAGGCCATAGACGCGTGTGATGCCAATACAACCCCAGGGGGTGTAAC
TGATGTTATCAAAAATTGGGATTCCTTGATACCAGATGAAATGCCAGATTCTCCCATTCAAGAAAAATCAGAATGTCAGGACATGTCTCT
TTCTTCACCGACCAGCGTACTTGGTGGCTCCCGCCACCAGAGCCACACTGCAGAGGCTGGGCCCCGGAAGAGCCCGGTCGGGATGCTGGA
CCTGTCTTCCTGGAGCTCCCCTGAGGTCCTCAGGAAGGACTGGACCCTGGAGCCCTGGCCCAGCCTCCCCGTGACACCCCACTCAGGAGC
CCTGAGCCTGTGCAGTGCCGACACATCCCTGGGGGACAGGGCGGACACCTCGCTGCCACAGACCCAGGGGCCGGGGCTGCTTTGTTCCCC
AGGCGTGTCTGCAGCAGCGCTGGCACTGCAGTGGGCCGAGTCTCCGCCGGCTGACGACCACCATGTGCAGAGGACGGCTGTGGAGAAAGA
TGTCGAAGATTTTATCACAACATCCTTTGATTCTCAAGAAACATTAAGTTCACCTCCTCCTGGATTAGAAGGAAAAGCTGATAGAAGTGA
GAAAAGTGACGGCTCGGGTTTTGGAGCAAGACTGAGCCCGGGGTCAGGAGGCCCTGAGGCTCAAACTGCTGGTCCTGTGACCCCTGCTTC
CATCTCTGGAAGGTTTCAGCCGCTGCCGGAAGCCATGAAGGAGAAGGAAGTGCGTCCGAAGCACGTGAAGGCTTTACTGCAGATGGTGCG
TGACGAGAGCCACCAGATCCTGGCGCTGTCAGAAGGCCTTGCACCCCCAAGCGGCGAGCCACACCCACCCCGGAAGGAAGACGAGATACA
GGACATCTCGCTCCATGGGGGAAAGACGCAGGAAGTGCCCACCGCGTGCCCCGATTGGAGAGGGGACCTTCTGCAGGTTGTGCAAGAGGC
CTTTGAAAAAGAGCAGGAGATGCAGGGGGTTGAGCTGCAGCCCCGACTCAGTGGCTCAGATCTGGGGGGTCACAGCTCCCTGCTCGAAAG
GCTGGAGAAGATCATCCGTGAGCAGGGAGACCTGCAGGAAAAGTCCCTGGAGCATCTTCGCTTGCCGGACCGGAGCAGCCTGCTGTCCGA
GATCCAGGCGCTGCGTGCCCAGCTGCGCATGACGCACCTGCAGAACCAGGAGAAGCTGCAGCACTTGCGCACGGCGCTGACAAGCGCAGA
GGCGCGCGGGAGCCAGCAGGAGCACCAGCTGCGCAGGCAGGTTGAACTGCTGGCTTATAAAGTAGAGCAGGAGAAGTGCATTGCTGGTGA
CTTGCAGAAGACGCTGAGTGAAGAGCAAGAGAAGGCAAACAGCGTGCAGAAGCTCCTGGCGGCGGAGCAGACTGTAGTGCGAGATTTGAA
GTCCGACCTCTGTGAGAGCAGGCAGAAGAGCGAACAGCTGTCCCGGTCCCTCTGCGAGGTGCAGCAGGAGGTCCTCCAGCTGAGATCCAT
GCTGAGCAGTAAGGAGAACGAGCTGAAGGCCGCGCTTCAGGAGCTGGAGAGTGAGCAGGGGAAGGGGCGTGCCCTGCAGAGCCAGCTGGA
GGAGGAGCAGCTGCGGCACCTGCAGAGGGAGAGCCAGAGTGCCAAGGCCCTGGAGGAGCTGCGGGCGTCTTTGGAGACACAGCGTGCTCA
GAGCAGTCGACTCTGCGTGGCACTGAAACACGAGCAGACGGCCAAGGACAACCTGCAGAAGGAGCTGCGTATCGAGCACTCACGCTGCGA
GGCCTTGCTGGCTCAGGAGCGGAGCCAGCTCTCTGAGCTCCAGAAGGACCTTGCGGCTGAGAAGAGCCGCACCCTGGAGCTGTCAGAGGC
CTTGCGGCACGAGCGGCTCCTGACCGAGCAGCTGAGCCAGAGGACACAGGAGGCTTGCGTGCACCAGGACACACAGGCCCATCACGCTCT
GCTGCAGAAGCTGAAGGAGGAGAAGTCCCGGGTGGTGGACTTGCAAGCGATGCTTGAAAAGGTGCAGCAGCAAGCCCTGCATTCTCAGCA
GCAGCTTGAGGCTGAGGCTCAGAAGCACTGTGAGGCGCTCAGGAGAGAGAAGGAGGTAAGTGCCACACTGAAGTCGACGGTGGAAGCCCT
GCACACCCAAAAACGAGAGCTGAGATGCTCTCTGGAGAGAGAGAGGGAGAAACCAGCGTGGTTGCAGGCAGAATTAGAGCAGTCACACCC
ACGGTTGAAAGAGCAAGAAGGACGCAAGGCTGCGAGGAGGAGCGCGGAGGCCAGGCAGAGCCCAGCGGCTGCGGAGCAGTGGAGGAAGTG
GCAGAGAGACAAGGAGAAGCTGCGAGAATTAGAACTGCAGCGTCAGCGTGACTTGCATAAGATCAAGCAGCTTCAGCAGACAGTGAGAGA
CCTGGAGTCGAAGGACGAGGTGCCTGGCAGCCGCCTCCACCTAGGTTCTGCCCGCAGGGCTGCCGGCTCGGATGCGGACCACCTCCGGGA
ACAGCAGCGAGAGCTGGAGGCGATGAGGCAGCGGCTGCTCTCTGCCGCCCGGCTTCTCACCAGCTTCACCAGCCAGGCCGTGGACAGGAC
AGTTAATGATTGGACGTCATCCAATGAGAAAGCAGTGATGTCTTTACTGCACACGTTGGAGGAGCTGAAGTCTGACTTGAGCAGGCCCAC
CTCCTCCCAGAAAAAAATGGCAGCAGAGCTGCAGTTCCAGTTTGTGGACGTCCTGCTGAAAGACAATGTTTCCCTCACAAAAGCGCTCAG
CACGGTGACCCAGGAGAAGCTGGAGCTGAGCAGAGCCGTGTCTAAGCTTGAGAAGTTGCTGAAGCACCATCTGCAGAAGGGCTGCAGCCC
AAGCAGGTCGGAAAGGTCTGCTTGGAAGCCAGACGAAACGGCTCCACAGAGTTCCCTGAGGCGCCCAGACCCCGGCCGGCTTCCACCAGC
TGCCAGCGAGGAAGCACACACCAGCAATGTCAAGATGGAAAAATTGTACCTGCATTACTTGAGAGCAGAGAGCTTTAGAAAAGCTCTGAT
TTATCAAAAGAAGTATCTTTTGCTGTTGATTGGTGGATTCCAGGATTCTGAACAAGAAACACTCTCCATGATTGCCCATTTGGGGGTATT
TCCTTCCAAAGCAGAACGGAAAATCACATCTCGTCCTTTCACCAGGTTCCGCACGGCCGTCAGGGTGGTCATTGCAATATTAAGATTACG
TTTTTTGGTTAAGAAATGGCAAGAAGTAGATCGGAAAGGAGCTCTGGCACAAGGCAAAGCCCCTCGCCCAGGGCCCCGAGCACGACAGCC
GCAGTCTCCACCCAGAACCAGAGAGTCCCCCCCAACCCGGGATGTACCCTCTGGCCACACCAGGGACCCTGCCAGAGGCCGCAGACTGGC
AGCAGCAGCCTCCCCACACAGTGGGGGAAGAGCCACTCCATCCCCAAATTCAAGATTAGAAAGATCCCTGACTGCTTCTCAAGATCCAGA
ACATTCCTTGACAGAGTATATTCACCATTTAGAAGTGATCCAGCAAAGATTGGGAGGGGTACTACCAGATTCTACTTCAAAGAAATCCTG
CCACCCGATGATTAAACAGTGAATAAAATGTCATGGCTCTTTCCTGCGACAATTCTATTTGAGGAAAAGATTTGTTTTTCCCTTTTCCCA
AGGAAGCTCGTGGGACAGCATGGGCACTACTCTTCATGTGCGGTGACACCAGCCCCCAGATGCCTTGAATTAAGTGTCCTCACCTTTATG
CATGACTGCAAAGCCAGCTGGAGCATTTTCTATGGAGCCTCCGTATGTTTTAGGCCCATGACCTTCGTGAGGTGACGGGCACTCACTCCC
ATGAGCCCTGGCTGTGTGCTGTTGTGTGCCTATCGGCAGATCCATCCTTCCTGCCTCCAAGGAGGATACACAGAGAATGGCTTCCTGTTG
TTTTGTTTATTTTCTTAACGTGTACAGATGGAAACTTCATTTAAAAATAAAAACAAAACAACTCAAAAAGGAATAAAATTTAATCACTGT

>83054_83054_1_SLC37A1-PCNT_SLC37A1_chr21_43987168_ENST00000352133_PCNT_chr21_47831103_ENST00000359568_length(amino acids)=2079AA_BP=0
MARLPAGIRFIISFSRDQWYRAFIFILTFLLYASFHLSRKPISIVKGELHKYCTAWDEADVRFSSQNRKSGSAAPHQLPDNETDCGWAPF
DKNNYQQLLGALDYSFLCAYAVGMYLSGIIGERLPIRYYLTFGMLASGAFTALFGLGYFYNIHSFGFYVVTQVINGLVQTTGWPSVVTCL
GNWFGKGRRGLIMGVWNSHTSVGNILGSLIAGYWVSTCWGLSFVVPGAIVAAMGIVCFLFLIEHPNDVRCSSTLVTHSKGYENGTNRLRL
QKQILKSEKNKPLDPEMQCLLLSDGKGSIHPNHVVILPGDGGSGTAAISFTGALKIPGVIEFSLCLLFAKLVSYTFLFWLPLYITNVDHL
DAKKAGELSTLFDVGGIFGGILAGVISDRLEKRASTCGLMLLLAAPTLYIFSTVSKMGLEATIAMLLLSGALVSGPYTLITTAVSADLVI
YTRSSEIEELKATIENLQENQKRLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSELLCSQAGGPRGQALQGELEAALE
AKEALSRLLADQERRHSQALEALQQRLQGAEEAAELQLAELERNVALREAEVEDMASRIQEFEAALKAKEATIAERNLEIDALNQRKAAH
SAELEAVLLALARIRRALEQQPLAAGAAPPELQWLRAQCARLSRQLQVLHQRFLRCQVELDRRQARRATAHTRVPGAHPQPRMDGGAKAQ
VTGDVEASHDAALEPVVPDPQGDLQPVLVTLKDAPLCKQEGVMSVLTVCQRQLQSELLLVKNEMRLSLEDGGKGKEKVLEDCQLPKVDLV
AQVKQLQEKLNRLLYSMTFQNVDAADTKSLWPMASAHLLESSWSDDSCDGEEPDISPHIDTCDANTATGGVTDVIKNQAIDACDANTTPG
GVTDVIKNWDSLIPDEMPDSPIQEKSECQDMSLSSPTSVLGGSRHQSHTAEAGPRKSPVGMLDLSSWSSPEVLRKDWTLEPWPSLPVTPH
SGALSLCSADTSLGDRADTSLPQTQGPGLLCSPGVSAAALALQWAESPPADDHHVQRTAVEKDVEDFITTSFDSQETLSSPPPGLEGKAD
RSEKSDGSGFGARLSPGSGGPEAQTAGPVTPASISGRFQPLPEAMKEKEVRPKHVKALLQMVRDESHQILALSEGLAPPSGEPHPPRKED
EIQDISLHGGKTQEVPTACPDWRGDLLQVVQEAFEKEQEMQGVELQPRLSGSDLGGHSSLLERLEKIIREQGDLQEKSLEHLRLPDRSSL
LSEIQALRAQLRMTHLQNQEKLQHLRTALTSAEARGSQQEHQLRRQVELLAYKVEQEKCIAGDLQKTLSEEQEKANSVQKLLAAEQTVVR
DLKSDLCESRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQ
RAQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAH
HALLQKLKEEKSRVVDLQAMLEKVQQQALHSQQQLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLEREREKPAWLQAELEQ
SHPRLKEQEGRKAARRSAEARQSPAAAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQQTVRDLESKDEVPGSRLHLGSARRAAGSDADH
LREQQRELEAMRQRLLSAARLLTSFTSQAVDRTVNDWTSSNEKAVMSLLHTLEELKSDLSRPTSSQKKMAAELQFQFVDVLLKDNVSLTK
ALSTVTQEKLELSRAVSKLEKLLKHHLQKGCSPSRSERSAWKPDETAPQSSLRRPDPGRLPPAASEEAHTSNVKMEKLYLHYLRAESFRK
ALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERKITSRPFTRFRTAVRVVIAILRLRFLVKKWQEVDRKGALAQGKAPRPGPRA
RQPQSPPRTRESPPTRDVPSGHTRDPARGRRLAAAASPHSGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGVLPDSTSK

--------------------------------------------------------------
>83054_83054_2_SLC37A1-PCNT_SLC37A1_chr21_43987168_ENST00000398341_PCNT_chr21_47831103_ENST00000359568_length(transcript)=7094nt_BP=1756nt
TGGGAAGTTCGCGCAAGTGCGGCTCTGCAGGGAGGAGGGAGGGCCGAGGGGAAGGCCCTCGAGAGAGTGGAGGGCAACAGTGGCCACGGT
TCCTCTGTACTTCGTTTCTTCCCTTTATAGAATTGAGAGATTGCTGAGCCTAAATACATGTTGCTGCATTGCCTCCGAGAATGGCCGGAC
CTATCCCCACTCTCACCAAAACAGAGTGTGGGACTCACTGCTCCCTCGCCTACTAGAGCAGAGCCACTGCCAGAAGGAAGGGGACAAGAC
CCAGCAGGACACCTTCTTTCCACGCTTTCCAGCCTGTGGGAGCGGCAGGGGCAACAGAGAGAGGATCTGGAGCCAGGATTAATGACTCAT
TTATGAAGCATCTTATTCTGCGACCGAGGCTCAGTGGTCAGTGGCGACGTAAATGGCTCGACTCCCCGCTGGCATTCGCTTCATCATCTC
ATTCTCCAGGGATCAGTGGTACAGAGCCTTCATTTTTATTTTGACATTTCTGCTGTATGCAAGTTTTCACTTATCTCGAAAGCCTATCAG
CATAGTTAAGGGTGAGCTCCACAAGTACTGCACTGCTTGGGATGAAGCTGACGTCAGGTTCAGCAGCCAGAACAGGAAGTCTGGGTCCGC
TGCCCCCCACCAGCTCCCTGACAATGAGACCGACTGTGGCTGGGCACCGTTTGATAAGAACAACTATCAGCAGCTGCTTGGGGCCCTGGA
CTACTCCTTCCTGTGCGCCTATGCCGTGGGGATGTACCTCAGTGGCATCATTGGGGAGCGCCTGCCGATTAGGTATTACCTAACTTTCGG
GATGCTCGCCAGCGGAGCCTTCACCGCCCTGTTCGGCTTAGGGTATTTCTACAACATCCACAGTTTCGGATTCTACGTGGTAACTCAGGT
CATCAACGGGCTGGTGCAGACCACCGGCTGGCCCAGCGTCGTCACCTGCCTCGGCAACTGGTTTGGAAAAGGAAGGAGAGGTTTGATTAT
GGGGGTCTGGAACTCCCACACCTCCGTGGGCAACATCTTGGGGTCATTGATCGCTGGCTACTGGGTGTCCACATGCTGGGGCCTGTCCTT
CGTCGTGCCTGGAGCCATCGTGGCAGCCATGGGGATAGTGTGCTTTCTCTTCCTCATTGAACATCCGAACGACGTCAGGTGCTCCTCCAC
CCTGGTGACGCACTCAAAAGGCTATGAGAATGGTACAAACAGATTGAGACTCCAGAAGCAAATCTTGAAGAGCGAAAAGAACAAGCCTCT
GGACCCAGAGATGCAGTGCCTGCTGCTCTCAGATGGGAAGGGCTCCATCCACCCGAACCACGTCGTCATTCTCCCCGGGGACGGTGGGAG
TGGCACGGCCGCCATCAGCTTCACAGGGGCCTTGAAAATTCCAGGCGTGATAGAGTTCTCACTGTGTCTGCTGTTTGCCAAGCTGGTCAG
CTATACTTTCCTCTTCTGGCTGCCCCTGTACATCACGAATGTGGATCACCTTGATGCCAAAAAGGCGGGGGAGCTCTCCACCCTGTTTGA
CGTGGGCGGAATCTTTGGTGGGATCCTGGCAGGTGTGATCTCAGACCGACTGGAGAAAAGGGCCTCCACCTGCGGCCTGATGCTGCTGCT
CGCGGCCCCCACGCTCTACATCTTCTCCACCGTCAGCAAGATGGGGCTTGAGGCCACCATCGCCATGCTGCTGCTCAGCGGAGCCCTGGT
CAGTGGGCCCTACACACTCATCACCACCGCCGTCTCCGCCGACCTGGTCATATATACCAGAAGTTCTGAGATTGAAGAGCTGAAAGCCAC
TATTGAAAATCTGCAAGAGAATCAGAAACGATTACAAAAGGAGAAAGCAGAGGAAATTGAACAACTCCATGAAGTCATTGAGAAGCTGCA
GCACGAGCTGTCCCTCATGGGGCCTGTGGTGCACGAAGTCAGCGACAGTCAGGCTGGCAGTCTGCAGAGCGAGCTGCTCTGCTCCCAGGC
CGGGGGCCCTCGTGGGCAGGCCCTACAGGGCGAGCTCGAGGCTGCGCTGGAAGCCAAGGAGGCCCTGAGCCGGCTGCTGGCTGACCAGGA
GCGCAGGCACAGCCAGGCCCTGGAGGCCCTGCAGCAGCGCCTCCAGGGCGCAGAGGAGGCTGCGGAGCTACAGCTGGCTGAGCTGGAGCG
CAATGTAGCCCTCAGGGAGGCTGAGGTCGAAGACATGGCCTCCCGGATCCAGGAGTTCGAAGCGGCCCTGAAAGCAAAGGAAGCGACGAT
TGCCGAGAGAAATTTAGAAATCGACGCTCTGAACCAGCGGAAGGCGGCCCACTCTGCCGAGCTGGAGGCCGTCCTGTTGGCCTTGGCCCG
CATCCGCCGCGCCCTGGAGCAGCAGCCCCTGGCAGCCGGGGCGGCGCCTCCCGAGCTGCAGTGGCTCCGAGCGCAGTGTGCCCGCCTCAG
CCGCCAGCTGCAGGTGCTGCACCAGCGGTTCCTGAGGTGCCAGGTGGAGCTGGACAGGCGGCAGGCCCGCAGAGCCACAGCTCACACACG
GGTGCCCGGGGCCCACCCACAGCCTCGCATGGATGGTGGCGCCAAGGCCCAGGTCACCGGCGACGTGGAGGCCTCCCATGATGCTGCTTT
GGAGCCGGTTGTCCCTGACCCACAGGGTGATCTGCAGCCTGTCCTGGTGACGTTGAAGGATGCACCTCTCTGCAAGCAAGAAGGCGTGAT
GTCAGTGCTCACCGTCTGCCAGAGGCAGCTGCAGTCGGAGCTGCTCTTGGTGAAAAATGAAATGCGCCTGAGTCTGGAGGACGGCGGCAA
GGGTAAAGAAAAAGTACTGGAAGATTGTCAGCTGCCGAAGGTCGATCTCGTAGCTCAGGTGAAACAGCTTCAGGAAAAACTGAACCGTTT
GCTGTATTCCATGACCTTCCAGAATGTGGATGCTGCCGACACCAAATCTCTGTGGCCCATGGCCTCAGCACACCTGTTGGAGAGCAGCTG
GAGTGATGATTCCTGTGACGGAGAAGAGCCTGACATATCACCCCACATAGACACATGTGATGCCAATACAGCCACGGGGGGTGTAACTGA
TGTTATCAAAAATCAGGCCATAGACGCGTGTGATGCCAATACAACCCCAGGGGGTGTAACTGATGTTATCAAAAATTGGGATTCCTTGAT
ACCAGATGAAATGCCAGATTCTCCCATTCAAGAAAAATCAGAATGTCAGGACATGTCTCTTTCTTCACCGACCAGCGTACTTGGTGGCTC
CCGCCACCAGAGCCACACTGCAGAGGCTGGGCCCCGGAAGAGCCCGGTCGGGATGCTGGACCTGTCTTCCTGGAGCTCCCCTGAGGTCCT
CAGGAAGGACTGGACCCTGGAGCCCTGGCCCAGCCTCCCCGTGACACCCCACTCAGGAGCCCTGAGCCTGTGCAGTGCCGACACATCCCT
GGGGGACAGGGCGGACACCTCGCTGCCACAGACCCAGGGGCCGGGGCTGCTTTGTTCCCCAGGCGTGTCTGCAGCAGCGCTGGCACTGCA
GTGGGCCGAGTCTCCGCCGGCTGACGACCACCATGTGCAGAGGACGGCTGTGGAGAAAGATGTCGAAGATTTTATCACAACATCCTTTGA
TTCTCAAGAAACATTAAGTTCACCTCCTCCTGGATTAGAAGGAAAAGCTGATAGAAGTGAGAAAAGTGACGGCTCGGGTTTTGGAGCAAG
ACTGAGCCCGGGGTCAGGAGGCCCTGAGGCTCAAACTGCTGGTCCTGTGACCCCTGCTTCCATCTCTGGAAGGTTTCAGCCGCTGCCGGA
AGCCATGAAGGAGAAGGAAGTGCGTCCGAAGCACGTGAAGGCTTTACTGCAGATGGTGCGTGACGAGAGCCACCAGATCCTGGCGCTGTC
AGAAGGCCTTGCACCCCCAAGCGGCGAGCCACACCCACCCCGGAAGGAAGACGAGATACAGGACATCTCGCTCCATGGGGGAAAGACGCA
GGAAGTGCCCACCGCGTGCCCCGATTGGAGAGGGGACCTTCTGCAGGTTGTGCAAGAGGCCTTTGAAAAAGAGCAGGAGATGCAGGGGGT
TGAGCTGCAGCCCCGACTCAGTGGCTCAGATCTGGGGGGTCACAGCTCCCTGCTCGAAAGGCTGGAGAAGATCATCCGTGAGCAGGGAGA
CCTGCAGGAAAAGTCCCTGGAGCATCTTCGCTTGCCGGACCGGAGCAGCCTGCTGTCCGAGATCCAGGCGCTGCGTGCCCAGCTGCGCAT
GACGCACCTGCAGAACCAGGAGAAGCTGCAGCACTTGCGCACGGCGCTGACAAGCGCAGAGGCGCGCGGGAGCCAGCAGGAGCACCAGCT
GCGCAGGCAGGTTGAACTGCTGGCTTATAAAGTAGAGCAGGAGAAGTGCATTGCTGGTGACTTGCAGAAGACGCTGAGTGAAGAGCAAGA
GAAGGCAAACAGCGTGCAGAAGCTCCTGGCGGCGGAGCAGACTGTAGTGCGAGATTTGAAGTCCGACCTCTGTGAGAGCAGGCAGAAGAG
CGAACAGCTGTCCCGGTCCCTCTGCGAGGTGCAGCAGGAGGTCCTCCAGCTGAGATCCATGCTGAGCAGTAAGGAGAACGAGCTGAAGGC
CGCGCTTCAGGAGCTGGAGAGTGAGCAGGGGAAGGGGCGTGCCCTGCAGAGCCAGCTGGAGGAGGAGCAGCTGCGGCACCTGCAGAGGGA
GAGCCAGAGTGCCAAGGCCCTGGAGGAGCTGCGGGCGTCTTTGGAGACACAGCGTGCTCAGAGCAGTCGACTCTGCGTGGCACTGAAACA
CGAGCAGACGGCCAAGGACAACCTGCAGAAGGAGCTGCGTATCGAGCACTCACGCTGCGAGGCCTTGCTGGCTCAGGAGCGGAGCCAGCT
CTCTGAGCTCCAGAAGGACCTTGCGGCTGAGAAGAGCCGCACCCTGGAGCTGTCAGAGGCCTTGCGGCACGAGCGGCTCCTGACCGAGCA
GCTGAGCCAGAGGACACAGGAGGCTTGCGTGCACCAGGACACACAGGCCCATCACGCTCTGCTGCAGAAGCTGAAGGAGGAGAAGTCCCG
GGTGGTGGACTTGCAAGCGATGCTTGAAAAGGTGCAGCAGCAAGCCCTGCATTCTCAGCAGCAGCTTGAGGCTGAGGCTCAGAAGCACTG
TGAGGCGCTCAGGAGAGAGAAGGAGGTAAGTGCCACACTGAAGTCGACGGTGGAAGCCCTGCACACCCAAAAACGAGAGCTGAGATGCTC
TCTGGAGAGAGAGAGGGAGAAACCAGCGTGGTTGCAGGCAGAATTAGAGCAGTCACACCCACGGTTGAAAGAGCAAGAAGGACGCAAGGC
TGCGAGGAGGAGCGCGGAGGCCAGGCAGAGCCCAGCGGCTGCGGAGCAGTGGAGGAAGTGGCAGAGAGACAAGGAGAAGCTGCGAGAATT
AGAACTGCAGCGTCAGCGTGACTTGCATAAGATCAAGCAGCTTCAGCAGACAGTGAGAGACCTGGAGTCGAAGGACGAGGTGCCTGGCAG
CCGCCTCCACCTAGGTTCTGCCCGCAGGGCTGCCGGCTCGGATGCGGACCACCTCCGGGAACAGCAGCGAGAGCTGGAGGCGATGAGGCA
GCGGCTGCTCTCTGCCGCCCGGCTTCTCACCAGCTTCACCAGCCAGGCCGTGGACAGGACAGTTAATGATTGGACGTCATCCAATGAGAA
AGCAGTGATGTCTTTACTGCACACGTTGGAGGAGCTGAAGTCTGACTTGAGCAGGCCCACCTCCTCCCAGAAAAAAATGGCAGCAGAGCT
GCAGTTCCAGTTTGTGGACGTCCTGCTGAAAGACAATGTTTCCCTCACAAAAGCGCTCAGCACGGTGACCCAGGAGAAGCTGGAGCTGAG
CAGAGCCGTGTCTAAGCTTGAGAAGTTGCTGAAGCACCATCTGCAGAAGGGCTGCAGCCCAAGCAGGTCGGAAAGGTCTGCTTGGAAGCC
AGACGAAACGGCTCCACAGAGTTCCCTGAGGCGCCCAGACCCCGGCCGGCTTCCACCAGCTGCCAGCGAGGAAGCACACACCAGCAATGT
CAAGATGGAAAAATTGTACCTGCATTACTTGAGAGCAGAGAGCTTTAGAAAAGCTCTGATTTATCAAAAGAAGTATCTTTTGCTGTTGAT
TGGTGGATTCCAGGATTCTGAACAAGAAACACTCTCCATGATTGCCCATTTGGGGGTATTTCCTTCCAAAGCAGAACGGAAAATCACATC
TCGTCCTTTCACCAGGTTCCGCACGGCCGTCAGGGTGGTCATTGCAATATTAAGATTACGTTTTTTGGTTAAGAAATGGCAAGAAGTAGA
TCGGAAAGGAGCTCTGGCACAAGGCAAAGCCCCTCGCCCAGGGCCCCGAGCACGACAGCCGCAGTCTCCACCCAGAACCAGAGAGTCCCC
CCCAACCCGGGATGTACCCTCTGGCCACACCAGGGACCCTGCCAGAGGCCGCAGACTGGCAGCAGCAGCCTCCCCACACAGTGGGGGAAG
AGCCACTCCATCCCCAAATTCAAGATTAGAAAGATCCCTGACTGCTTCTCAAGATCCAGAACATTCCTTGACAGAGTATATTCACCATTT
AGAAGTGATCCAGCAAAGATTGGGAGGGGTACTACCAGATTCTACTTCAAAGAAATCCTGCCACCCGATGATTAAACAGTGAATAAAATG
TCATGGCTCTTTCCTGCGACAATTCTATTTGAGGAAAAGATTTGTTTTTCCCTTTTCCCAAGGAAGCTCGTGGGACAGCATGGGCACTAC
TCTTCATGTGCGGTGACACCAGCCCCCAGATGCCTTGAATTAAGTGTCCTCACCTTTATGCATGACTGCAAAGCCAGCTGGAGCATTTTC
TATGGAGCCTCCGTATGTTTTAGGCCCATGACCTTCGTGAGGTGACGGGCACTCACTCCCATGAGCCCTGGCTGTGTGCTGTTGTGTGCC
TATCGGCAGATCCATCCTTCCTGCCTCCAAGGAGGATACACAGAGAATGGCTTCCTGTTGTTTTGTTTATTTTCTTAACGTGTACAGATG

>83054_83054_2_SLC37A1-PCNT_SLC37A1_chr21_43987168_ENST00000398341_PCNT_chr21_47831103_ENST00000359568_length(amino acids)=2079AA_BP=0
MARLPAGIRFIISFSRDQWYRAFIFILTFLLYASFHLSRKPISIVKGELHKYCTAWDEADVRFSSQNRKSGSAAPHQLPDNETDCGWAPF
DKNNYQQLLGALDYSFLCAYAVGMYLSGIIGERLPIRYYLTFGMLASGAFTALFGLGYFYNIHSFGFYVVTQVINGLVQTTGWPSVVTCL
GNWFGKGRRGLIMGVWNSHTSVGNILGSLIAGYWVSTCWGLSFVVPGAIVAAMGIVCFLFLIEHPNDVRCSSTLVTHSKGYENGTNRLRL
QKQILKSEKNKPLDPEMQCLLLSDGKGSIHPNHVVILPGDGGSGTAAISFTGALKIPGVIEFSLCLLFAKLVSYTFLFWLPLYITNVDHL
DAKKAGELSTLFDVGGIFGGILAGVISDRLEKRASTCGLMLLLAAPTLYIFSTVSKMGLEATIAMLLLSGALVSGPYTLITTAVSADLVI
YTRSSEIEELKATIENLQENQKRLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSELLCSQAGGPRGQALQGELEAALE
AKEALSRLLADQERRHSQALEALQQRLQGAEEAAELQLAELERNVALREAEVEDMASRIQEFEAALKAKEATIAERNLEIDALNQRKAAH
SAELEAVLLALARIRRALEQQPLAAGAAPPELQWLRAQCARLSRQLQVLHQRFLRCQVELDRRQARRATAHTRVPGAHPQPRMDGGAKAQ
VTGDVEASHDAALEPVVPDPQGDLQPVLVTLKDAPLCKQEGVMSVLTVCQRQLQSELLLVKNEMRLSLEDGGKGKEKVLEDCQLPKVDLV
AQVKQLQEKLNRLLYSMTFQNVDAADTKSLWPMASAHLLESSWSDDSCDGEEPDISPHIDTCDANTATGGVTDVIKNQAIDACDANTTPG
GVTDVIKNWDSLIPDEMPDSPIQEKSECQDMSLSSPTSVLGGSRHQSHTAEAGPRKSPVGMLDLSSWSSPEVLRKDWTLEPWPSLPVTPH
SGALSLCSADTSLGDRADTSLPQTQGPGLLCSPGVSAAALALQWAESPPADDHHVQRTAVEKDVEDFITTSFDSQETLSSPPPGLEGKAD
RSEKSDGSGFGARLSPGSGGPEAQTAGPVTPASISGRFQPLPEAMKEKEVRPKHVKALLQMVRDESHQILALSEGLAPPSGEPHPPRKED
EIQDISLHGGKTQEVPTACPDWRGDLLQVVQEAFEKEQEMQGVELQPRLSGSDLGGHSSLLERLEKIIREQGDLQEKSLEHLRLPDRSSL
LSEIQALRAQLRMTHLQNQEKLQHLRTALTSAEARGSQQEHQLRRQVELLAYKVEQEKCIAGDLQKTLSEEQEKANSVQKLLAAEQTVVR
DLKSDLCESRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQ
RAQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAH
HALLQKLKEEKSRVVDLQAMLEKVQQQALHSQQQLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLEREREKPAWLQAELEQ
SHPRLKEQEGRKAARRSAEARQSPAAAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQQTVRDLESKDEVPGSRLHLGSARRAAGSDADH
LREQQRELEAMRQRLLSAARLLTSFTSQAVDRTVNDWTSSNEKAVMSLLHTLEELKSDLSRPTSSQKKMAAELQFQFVDVLLKDNVSLTK
ALSTVTQEKLELSRAVSKLEKLLKHHLQKGCSPSRSERSAWKPDETAPQSSLRRPDPGRLPPAASEEAHTSNVKMEKLYLHYLRAESFRK
ALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERKITSRPFTRFRTAVRVVIAILRLRFLVKKWQEVDRKGALAQGKAPRPGPRA
RQPQSPPRTRESPPTRDVPSGHTRDPARGRRLAAAASPHSGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGVLPDSTSK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SLC37A1-PCNT

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Tgene	PCNT	chr21:43987168	chr21:47831103	ENST00000359568		26	47	2983_3246	1705.0	3337.0	NEK2

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for SLC37A1-PCNT

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for SLC37A1-PCNT

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source