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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SLC44A5-PLEKHA7 (FusionGDB2 ID:83311)

Fusion Gene Summary for SLC44A5-PLEKHA7

Fusion gene summary

Fusion gene information	Fusion gene name: SLC44A5-PLEKHA7
	Fusion gene ID: 83311
		Hgene	Tgene
	Gene symbol	SLC44A5	PLEKHA7
	Gene ID	204962	144100
	Gene name	solute carrier family 44 member 5	pleckstrin homology domain containing A7
	Synonyms	CTL5	-
	Cytomap	1p31.1	11p15.2-p15.1
	Type of gene	protein-coding	protein-coding
	Description	choline transporter-like protein 5	pleckstrin homology domain-containing family A member 7PH domain-containing family A member 7pleckstrin homology domain containing, family A member 2pleckstrin homology domain containing, family A member 7pleckstrin homology domain-containing family A
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000370855, ENST00000370859, ENST00000469525, ENST00000535611,	ENST00000332954, ENST00000532079, ENST00000355661, ENST00000448080, ENST00000531066,
Fusion gene scores	* DoF score	8 X 8 X 3=192	11 X 9 X 4=396
	# samples	8	11
	** MAII score	log2(8/192*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(11/396*10)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SLC44A5 [Title/Abstract] AND PLEKHA7 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SLC44A5(76007120)-PLEKHA7(16812752), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across SLC44A5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PLEKHA7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS5.0	N/A	DB455667	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-

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Fusion Gene ORF analysis for SLC44A5-PLEKHA7

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000370855	ENST00000332954	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
5CDS-5UTR	ENST00000370859	ENST00000332954	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
5CDS-intron	ENST00000370855	ENST00000532079	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
5CDS-intron	ENST00000370859	ENST00000532079	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
5UTR-3CDS	ENST00000469525	ENST00000355661	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
5UTR-3CDS	ENST00000469525	ENST00000448080	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
5UTR-3CDS	ENST00000469525	ENST00000531066	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
5UTR-5UTR	ENST00000469525	ENST00000332954	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
5UTR-intron	ENST00000469525	ENST00000532079	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
In-frame	ENST00000370855	ENST00000355661	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
In-frame	ENST00000370855	ENST00000448080	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
In-frame	ENST00000370855	ENST00000531066	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
In-frame	ENST00000370859	ENST00000355661	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
In-frame	ENST00000370859	ENST00000448080	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
In-frame	ENST00000370859	ENST00000531066	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
intron-3CDS	ENST00000535611	ENST00000355661	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
intron-3CDS	ENST00000535611	ENST00000448080	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
intron-3CDS	ENST00000535611	ENST00000531066	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
intron-5UTR	ENST00000535611	ENST00000332954	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-
intron-intron	ENST00000535611	ENST00000532079	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000370859	SLC44A5	chr1	76007120	-	ENST00000531066	PLEKHA7	chr11	16812752	-	1933	159	150	1229	359
ENST00000370859	SLC44A5	chr1	76007120	-	ENST00000355661	PLEKHA7	chr11	16812752	-	2383	159	150	779	209
ENST00000370859	SLC44A5	chr1	76007120	-	ENST00000448080	PLEKHA7	chr11	16812752	-	2202	159	150	782	210
ENST00000370855	SLC44A5	chr1	76007120	-	ENST00000531066	PLEKHA7	chr11	16812752	-	1901	127	118	1197	359
ENST00000370855	SLC44A5	chr1	76007120	-	ENST00000355661	PLEKHA7	chr11	16812752	-	2351	127	118	747	209
ENST00000370855	SLC44A5	chr1	76007120	-	ENST00000448080	PLEKHA7	chr11	16812752	-	2170	127	118	750	210

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000370859	ENST00000531066	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-	0.015079714	0.98492026
ENST00000370859	ENST00000355661	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-	0.12111807	0.87888193
ENST00000370859	ENST00000448080	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-	0.050330315	0.94966966
ENST00000370855	ENST00000531066	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-	0.016255692	0.9837443
ENST00000370855	ENST00000355661	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-	0.15103333	0.8489667
ENST00000370855	ENST00000448080	SLC44A5	chr1	76007120	-	PLEKHA7	chr11	16812752	-	0.061477523	0.9385225

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Fusion Genomic Features for SLC44A5-PLEKHA7

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SLC44A5-PLEKHA7

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:76007120/chr11:16812752)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000355661

1067_1094

915

1122.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000448080

1067_1094

915

1123.0

Coiled coil

Ontology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

1_38

720.0

Topological domain

Cytoplasmic

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

264_265

720.0

Topological domain

Cytoplasmic

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

287_325

720.0

Topological domain

Extracellular

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

347_351

720.0

Topological domain

Cytoplasmic

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

373_374

720.0

Topological domain

Extracellular

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

396_460

720.0

Topological domain

Cytoplasmic

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

482_515

720.0

Topological domain

Extracellular

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

537_610

720.0

Topological domain

Cytoplasmic

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

60_242

720.0

Topological domain

Extracellular

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

632_649

720.0

Topological domain

Extracellular

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

671_719

720.0

Topological domain

Cytoplasmic

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

243_263

720.0

Transmembrane

Helical

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

266_286

720.0

Transmembrane

Helical

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

326_346

720.0

Transmembrane

Helical

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

352_372

720.0

Transmembrane

Helical

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

375_395

720.0

Transmembrane

Helical

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

39_59

720.0

Transmembrane

Helical

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

461_481

720.0

Transmembrane

Helical

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

516_536

720.0

Transmembrane

Helical

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

611_631

720.0

Transmembrane

Helical

Hgene

SLC44A5

chr1:76007120

chr11:16812752

ENST00000370855

650_670

720.0

Transmembrane

Helical

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000355661

700_801

915

1122.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000448080

700_801

915

1123.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000355661

567_599

915

1122.0

Compositional bias

Note=Pro-rich

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000355661

845_942

915

1122.0

Compositional bias

Note=Pro-rich

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000448080

567_599

915

1123.0

Compositional bias

Note=Pro-rich

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000448080

845_942

915

1123.0

Compositional bias

Note=Pro-rich

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000355661

164_282

915

1122.0

Domain

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000355661

54_87

915

1122.0

Domain

WW 2

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000355661

9_42

915

1122.0

Domain

WW 1

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000448080

164_282

915

1123.0

Domain

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000448080

54_87

915

1123.0

Domain

WW 2

Tgene

PLEKHA7

chr1:76007120

chr11:16812752

ENST00000448080

9_42

915

1123.0

Domain

WW 1

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Fusion Gene Sequence for SLC44A5-PLEKHA7

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>83311_83311_1_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370855_PLEKHA7_chr11_16812752_ENST00000355661_length(transcript)=2351nt_BP=127nt
AGGTTCAGTGTTGATGGAGTTATTGAAGAAATGATGGAGTAAGAGACTCTTTTCTAAGCAACTCAAGTTTGCAGTGATTCAGGCCTACTT
CTGAAGAGACAGCCTTTTATCTCAATGAATGACACAGGAAGATGAAGCACCTCCCAGGCCCCCACTCCCCGAACTCTACAGCCCAGAGGA
CCAGCCCCCGGCTGTGCCGCCTCTGCCAAGAGAGGCCACCATCATCCGGCACACATCTGTGCGGGGCCTCAAGCGGCAGTCAGACGAGAG
GAAGCGAGACCGGGAGCTGGGGCAGTGTGTGAATGGGGATTCCAGGGTGGAGCTGCGGTCGTATGTCAGTGAGCCTGAGCTGGCGACCCT
CAGCGGGGACATGGCCCAGCCCTCCCTAGGACTTGTGGGCCCTGAGAGCAGGTACCAGACGCTGCCAGGCAGAGGGCTCTCAGGGTCCAC
GTCAAGGCTCCAGCAGTCGTCCACCATTGCTCCCTACGTCACACTCCGGAGGGGTCTCAATGCCGAAAGCAGCAAGGCGACCTTCCCTAG
ACCTAAGAGTGCCTTGGAGCGCCTGTACTCAGGGGATCACCAGCGAGGCAAGATGAGTGCAGAGGAGCAGCTGGAGCGCATGAAGCGACA
CCAGAAGGCCCTGGTCCGAGAGCGCAAGAGGACACTGGGCCAAGGGGAGAGGACGGGCCTGCCCTCATCTCGCTACCTCAGCCGGCCGCT
CCCTGGAGATCTTGGCTCAGTATGTTAGGAGGGGCCAGGCAGCGGGGCAGGGACAGGGAGCCGAGTGCCCCTCAGAGTCCCCCAAACACA
AGCACATCACACCTCCCAGTGAGAGAGCTGTCCATTGACCTACATGGTTCAGAGAACACCCCACGGGGCTGTTTGTCCACGACCCAGGCT
GGACGAATGCCTGGTCAGAGGGTGACCTGAACCAGAGCTGGAGTGAGGATCAAACAGGCCCAGGAGCCTGAGGAAATACCCAGTCAGTCC
TCCCAGCCGCGATGGAGAGGGGCCTTTGCAGGCGTTCGGAATCTCGGCTGAATTCAGGACCTGGGAATACAGGGTTCAGAGAGGAGAGGA
GGAAGATGGTGACATGATTTGGTTAGAAGCACAAGCAAACTGATCAGCCTCCCAGACCTGCCAGCAGATGCTGTGTGAGGGTGATGGAGC
ACGGGGTCACACCCCTGCCCCAAGGGCCACTGGTCTCCCTGGGCTTGCAGTGCAGAGGCCTCAGGGTGTCTGGGATTGCTGGGGAGGCCT
GTGCTGCCCCCTGGTGGCGCTTCCTGGCGCTGCGCCCTGTCCACAGTCACCTTAGGTCCCTTTGGAAACATTCCATTTGACTTTTCCCTG
TTGTTTGAAATCCCATGTTTCCCTAAACCTCTAGCCTGATTGTTCTTTCCCTAATTCATTGCACAAGCTCCTTTGCTTTTAGTGTTACCG
CTCATTGCCTCTCTAATCCTGCCTGATTGTGTTTACAGAAGCTTCTGATTTGCATTGAACATGCTCTAACTGGCCTGTGCTACTTATTAC
CGGGCTTGTAATAGCGGTTCTTGTCTCCATAGCCTGTTGAGTGTTCCCAGATGTGACTCACCTTTCTGCTGCCCTCTTCATGCAGGCCTA
CTGACTCATAATTCACTTGTCCCAAAAGCCACCCCACAAGCCTGAGCCAACCTGCTGCCTGACGCCACAGTCATTGGCAGAGGTCTGGGC
ATTATTAATTTATAAAAATCCATGCTTTACACCTGGACAGTAGACAGGGACTTCAGAGATTGCACGTTTGAATACATTCTCCCAAGACTG
AGGTTGTTCGGTTTTAATTCCTGTAGTCCAATCACACAATTTCTTATGGAAAACCTTTTGTGTTTCTGGTATTTAATAACTTGAAGGGAT
AGCAAAATATACTGTGTATTCAGAGGGCCTCTCTGCAGCTGCTAGCTCAGACACCAAAGGGGTAAGGCCCAGGACATTCATATCTTTAAA
AGCTGCAAACCTGGTAACCTTTAAACTTTTAAAACAAATGTCATATGGGGTAACACTGACCTTTTATAATTTGATGTCTCAAATGTAGAG
ATTATCTAAAAATCGTAACTTGAATACCTTGTAATTTTTCTCTTAAAAAAGAAGACTTGTGTAAGTCTCTGCATCAACGCCAATAAACAT
GTTGCTTAATAATAATGGATTGGCGTGGTTCTTCCCCAGGATACCTTATAGAGTCTAGTGAACTTTTCCTGTTTGTGGAAACAATCAGGC
TGGGTTTAAATGAGGACTTGTCTCTATTTGGAGCATTTGTGAGCGTGTAAGGAAATGAGTGTTTTCTTTGTGAATCATTAAATTGATTTT

>83311_83311_1_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370855_PLEKHA7_chr11_16812752_ENST00000355661_length(amino acids)=209AA_BP=2
MTQEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDRELGQCVNGDSRVELRSYVSEPELATLSGDMAQPSL
GLVGPESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAESSKATFPRPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERK

--------------------------------------------------------------
>83311_83311_2_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370855_PLEKHA7_chr11_16812752_ENST00000448080_length(transcript)=2170nt_BP=127nt
AGGTTCAGTGTTGATGGAGTTATTGAAGAAATGATGGAGTAAGAGACTCTTTTCTAAGCAACTCAAGTTTGCAGTGATTCAGGCCTACTT
CTGAAGAGACAGCCTTTTATCTCAATGAATGACACAGCAGGAAGATGAAGCACCTCCCAGGCCCCCACTCCCCGAACTCTACAGCCCAGA
GGACCAGCCCCCGGCTGTGCCGCCTCTGCCAAGAGAGGCCACCATCATCCGGCACACATCTGTGCGGGGCCTCAAGCGGCAGTCAGACGA
GAGGAAGCGAGACCGGGAGCTGGGGCAGTGTGTGAATGGGGATTCCAGGGTGGAGCTGCGGTCGTATGTCAGTGAGCCTGAGCTGGCGAC
CCTCAGCGGGGACATGGCCCAGCCCTCCCTAGGACTTGTGGGCCCTGAGAGCAGGTACCAGACGCTGCCAGGCAGAGGGCTCTCAGGGTC
CACGTCAAGGCTCCAGCAGTCGTCCACCATTGCTCCCTACGTCACACTCCGGAGGGGTCTCAATGCCGAAAGCAGCAAGGCGACCTTCCC
TAGACCTAAGAGTGCCTTGGAGCGCCTGTACTCAGGGGATCACCAGCGAGGCAAGATGAGTGCAGAGGAGCAGCTGGAGCGCATGAAGCG
ACACCAGAAGGCCCTGGTCCGAGAGCGCAAGAGGACACTGGGCCAAGGGGAGAGGACGGGCCTGCCCTCATCTCGCTACCTCAGCCGGCC
GCTCCCTGGAGATCTTGGCTCAGTATGTTAGGAGGGGCCAGGCAGCGGGGCAGGGACAGGGAGCCGAGTGCCCCTCAGAGTCCCCCAAAC
ACAAGCACATCACACCTCCCAGTGAGAGAGCTGTCCATTGACCTACATGGTTCAGAGAACACCCCACGGGGCTGTTTGTCCACGACCCAG
GCTGGACGAATGCCTGGTCAGAGGGTGACCTGAACCAGAGCTGGAGTGAGGATCAAACAGGCCCAGGAGCCTGAGGAAATACCCAGTCAG
TCCTCCCAGCCGCGATGGAGAGGGGCCTTTGCAGGCGTTCGGAATCTCGGCTGAATTCAGGACCTGGGAATACAGGGTTCAGAGAGGAGA
GGAGGAAGATGGTGACATGATTTGGTTAGAAGCACAAGCAAACTGATCAGCCTCCCAGACCTGCCAGCAGATGCTGTGTGAGGGTGATGG
AGCACGGGGTCACACCCCTGCCCCAAGGGCCACTGGTCTCCCTGGGCTTGCAGTGCAGAGGCCTCAGGGTGTCTGGGATTGCTGGGGAGG
CCTGTGCTGCCCCCTGGTGGCGCTTCCTGGCGCTGCGCCCTGTCCACAGTCACCTTAGGTCCCTTTGGAAACATTCCATTTGACTTTTCC
CTGTTGTTTGAAATCCCATGTTTCCCTAAACCTCTAGCCTGATTGTTCTTTCCCTAATTCATTGCACAAGCTCCTTTGCTTTTAGTGTTA
CCGCTCATTGCCTCTCTAATCCTGCCTGATTGTGTTTACAGAAGCTTCTGATTTGCATTGAACATGCTCTAACTGGCCTGTGCTACTTAT
TACCGGGCTTGTAATAGCGGTTCTTGTCTCCATAGCCTGTTGAGTGTTCCCAGATGTGACTCACCTTTCTGCTGCCCTCTTCATGCAGGC
CTACTGACTCATAATTCACTTGTCCCAAAAGCCACCCCACAAGCCTGAGCCAACCTGCTGCCTGACGCCACAGTCATTGGCAGAGGTCTG
GGCATTATTAATTTATAAAAATCCATGCTTTACACCTGGACAGTAGACAGGGACTTCAGAGATTGCACGTTTGAATACATTCTCCCAAGA
CTGAGGTTGTTCGGTTTTAATTCCTGTAGTCCAATCACACAATTTCTTATGGAAAACCTTTTGTGTTTCTGGTATTTAATAACTTGAAGG
GATAGCAAAATATACTGTGTATTCAGAGGGCCTCTCTGCAGCTGCTAGCTCAGACACCAAAGGGGTAAGGCCCAGGACATTCATATCTTT
AAAAGCTGCAAACCTGGTAACCTTTAAACTTTTAAAACAAATGTCATATGGGGTAACACTGACCTTTTATAATTTGATGTCTCAAATGTA
GAGATTATCTAAAAATCGTAACTTGAATACCTTGTAATTTTTCTCTTAAAAAAGAAGACTTGTGTAAGTCTCTGCATCAACGCCAATAAA

>83311_83311_2_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370855_PLEKHA7_chr11_16812752_ENST00000448080_length(amino acids)=210AA_BP=2
MTQQEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDRELGQCVNGDSRVELRSYVSEPELATLSGDMAQPS
LGLVGPESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAESSKATFPRPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRER

--------------------------------------------------------------
>83311_83311_3_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370855_PLEKHA7_chr11_16812752_ENST00000531066_length(transcript)=1901nt_BP=127nt
AGGTTCAGTGTTGATGGAGTTATTGAAGAAATGATGGAGTAAGAGACTCTTTTCTAAGCAACTCAAGTTTGCAGTGATTCAGGCCTACTT
CTGAAGAGACAGCCTTTTATCTCAATGAATGACACAGGAAGATGAAGCACCTCCCAGGCCCCCACTCCCCGAACTCTACAGCCCAGAGGA
CCAGCCCCCGGCTGTGCCGCCTCTGCCAAGAGAGGCCACCATCATCCGGCACACATCTGTGCGGGGCCTCAAGCGGCAGTCAGACGAGAG
GAAGCGAGACCGGGAGCTGGGGCAGTGTGTGAATGGGGATTCCAGGGTGGAGCTGCGGTCGTATGTCAGTGAGCCTGAGCTGGCGACCCT
CAGCGGGGACATGGCCCAGCCCTCCCTAGGACTTGTGGGCCCTGAGAGCAGGTACCAGACGCTGCCAGGCAGAGGGCTCTCAGGGTCCAC
GTCAAGGCTCCAGCAGTCGTCCACCATTGCTCCCTACGTCACACTCCGGAGGGGTCTCAATGCCGAAAGCAGCAAGGCGACCTTCCCTAG
ACCTAAGAGTGCCTTGGAGCGCCTGTACTCAGGGGATCACCAGCGAGGCAAGATGAGTGCAGAGGAGCAGCTGGAGCGCATGAAGCGACA
CCAGAAGGCCCTGGTCCGAGAGCGCAAGAGGACACTGGGCCAAGGGGAGAGGACGGGCCTGCCCTCATCTCGCTACCTCAGCCGGCCGCT
CCCTGGAGATCTTGGCTCATGGAAGCGTGAGCAGGACTTTGACCTGCAGTTGCTGGAACGGGTCGTGCAAGGGGAAAAAAAGGACAAGGA
GGAGAATGGCTGGTTGAAAGTGCAGGCCATGCCTGTCACTGAGTTGGACCTGGAGCCTCAAGACTATGACTTGGACATCAGCAGAGAGCT
GTCCAAACCAGAGAAGGTGTCAATCCCTGAGCGCTACGTGGAGCTAGATCCCGAAGAGCCACCCAGCCTTGAGGAGCTGCAGGCGCGGTA
CCGCAAAGCCGAGAAGATCCGCAACATCCTCGCCCGGTCAAGCATGTGCAACCTACAGCCGACCTCAGGCCAGGACCAGAACAGTGTGGC
TGACCTGGACTTGCAGCTGCAGGAGCAGGAGCGCATCATCAACATCTCCTACGCCCTGGCCTCCGAGGCCTCCCAGCGTAGCAAGCAGGT
GGCAGCCCAGGCAGTGACTGACCCGTGACCCAGCATGCAAAGAAGCCTGGAGCCAGGGGCCCAGTGGAACCAGCTTCCTCCAAGGAGATG
ACCTTTCTGCCCCCAAGGAAACCCCTTCCAGCTGAGCAGGGAATCCGGCCGGAGGAAGGAGCAGCTTACCGACTGCGGGTGTTCACCACA
GGCCAGGCCCTAATATGCACCCACTAGTTTAGCTCAGACTCCTCTCTACATATGAATGGCAAAGGCACTTTTGATATACACTGTAAAATA
CACTGTATTTTAGAATCGGAATCTATTTTCTAATGTTCCCCTCAAGGGCTGAGTGGCAGGAAGGTTGAGGATGCAGGACTTTGCAGCTGC
ACGTACAGATTCAGGTACTTCTGGGTGACAGGTGTTGTGGGGGCAGGAAGGGCGGGGCAAGCCGAGGCTAGTCCAACTTCCAATGACCTC
AGGAGAAAGTGAGATTTAAAGAGGTGTTCCCAGTAGACTCCAGCAAGAGGCTGGTTGGCGTGCTGTCTGGGAGAAGAGGGGCCCTTGGCT
GCAGAGATCAGCTGTCCCTGACCTGATGACCAGCTCTGTGTGAAACTCCACGAGGATCACACGTGGAGCCCAAGTCTGTGCCTTGCCCCT
TGGGTTTGGCTTAGGGGCAACAGTGTGTTCAAGAGGACTGGGGCCCACAACCTGCCCCCAGGCTTCCTCCAGCAAAAGGCTCTTGTCAGA

>83311_83311_3_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370855_PLEKHA7_chr11_16812752_ENST00000531066_length(amino acids)=359AA_BP=2
MTQEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDRELGQCVNGDSRVELRSYVSEPELATLSGDMAQPSL
GLVGPESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAESSKATFPRPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERK
RTLGQGERTGLPSSRYLSRPLPGDLGSWKREQDFDLQLLERVVQGEKKDKEENGWLKVQAMPVTELDLEPQDYDLDISRELSKPEKVSIP

--------------------------------------------------------------
>83311_83311_4_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370859_PLEKHA7_chr11_16812752_ENST00000355661_length(transcript)=2383nt_BP=159nt
ACAGTAGTGAATCGTAGCATGTTAGAGTTAGAAGGTTCAGTGTTGATGGAGTTATTGAAGAAATGATGGAGTAAGAGACTCTTTTCTAAG
CAACTCAAGTTTGCAGTGATTCAGGCCTACTTCTGAAGAGACAGCCTTTTATCTCAATGAATGACACAGGAAGATGAAGCACCTCCCAGG
CCCCCACTCCCCGAACTCTACAGCCCAGAGGACCAGCCCCCGGCTGTGCCGCCTCTGCCAAGAGAGGCCACCATCATCCGGCACACATCT
GTGCGGGGCCTCAAGCGGCAGTCAGACGAGAGGAAGCGAGACCGGGAGCTGGGGCAGTGTGTGAATGGGGATTCCAGGGTGGAGCTGCGG
TCGTATGTCAGTGAGCCTGAGCTGGCGACCCTCAGCGGGGACATGGCCCAGCCCTCCCTAGGACTTGTGGGCCCTGAGAGCAGGTACCAG
ACGCTGCCAGGCAGAGGGCTCTCAGGGTCCACGTCAAGGCTCCAGCAGTCGTCCACCATTGCTCCCTACGTCACACTCCGGAGGGGTCTC
AATGCCGAAAGCAGCAAGGCGACCTTCCCTAGACCTAAGAGTGCCTTGGAGCGCCTGTACTCAGGGGATCACCAGCGAGGCAAGATGAGT
GCAGAGGAGCAGCTGGAGCGCATGAAGCGACACCAGAAGGCCCTGGTCCGAGAGCGCAAGAGGACACTGGGCCAAGGGGAGAGGACGGGC
CTGCCCTCATCTCGCTACCTCAGCCGGCCGCTCCCTGGAGATCTTGGCTCAGTATGTTAGGAGGGGCCAGGCAGCGGGGCAGGGACAGGG
AGCCGAGTGCCCCTCAGAGTCCCCCAAACACAAGCACATCACACCTCCCAGTGAGAGAGCTGTCCATTGACCTACATGGTTCAGAGAACA
CCCCACGGGGCTGTTTGTCCACGACCCAGGCTGGACGAATGCCTGGTCAGAGGGTGACCTGAACCAGAGCTGGAGTGAGGATCAAACAGG
CCCAGGAGCCTGAGGAAATACCCAGTCAGTCCTCCCAGCCGCGATGGAGAGGGGCCTTTGCAGGCGTTCGGAATCTCGGCTGAATTCAGG
ACCTGGGAATACAGGGTTCAGAGAGGAGAGGAGGAAGATGGTGACATGATTTGGTTAGAAGCACAAGCAAACTGATCAGCCTCCCAGACC
TGCCAGCAGATGCTGTGTGAGGGTGATGGAGCACGGGGTCACACCCCTGCCCCAAGGGCCACTGGTCTCCCTGGGCTTGCAGTGCAGAGG
CCTCAGGGTGTCTGGGATTGCTGGGGAGGCCTGTGCTGCCCCCTGGTGGCGCTTCCTGGCGCTGCGCCCTGTCCACAGTCACCTTAGGTC
CCTTTGGAAACATTCCATTTGACTTTTCCCTGTTGTTTGAAATCCCATGTTTCCCTAAACCTCTAGCCTGATTGTTCTTTCCCTAATTCA
TTGCACAAGCTCCTTTGCTTTTAGTGTTACCGCTCATTGCCTCTCTAATCCTGCCTGATTGTGTTTACAGAAGCTTCTGATTTGCATTGA
ACATGCTCTAACTGGCCTGTGCTACTTATTACCGGGCTTGTAATAGCGGTTCTTGTCTCCATAGCCTGTTGAGTGTTCCCAGATGTGACT
CACCTTTCTGCTGCCCTCTTCATGCAGGCCTACTGACTCATAATTCACTTGTCCCAAAAGCCACCCCACAAGCCTGAGCCAACCTGCTGC
CTGACGCCACAGTCATTGGCAGAGGTCTGGGCATTATTAATTTATAAAAATCCATGCTTTACACCTGGACAGTAGACAGGGACTTCAGAG
ATTGCACGTTTGAATACATTCTCCCAAGACTGAGGTTGTTCGGTTTTAATTCCTGTAGTCCAATCACACAATTTCTTATGGAAAACCTTT
TGTGTTTCTGGTATTTAATAACTTGAAGGGATAGCAAAATATACTGTGTATTCAGAGGGCCTCTCTGCAGCTGCTAGCTCAGACACCAAA
GGGGTAAGGCCCAGGACATTCATATCTTTAAAAGCTGCAAACCTGGTAACCTTTAAACTTTTAAAACAAATGTCATATGGGGTAACACTG
ACCTTTTATAATTTGATGTCTCAAATGTAGAGATTATCTAAAAATCGTAACTTGAATACCTTGTAATTTTTCTCTTAAAAAAGAAGACTT
GTGTAAGTCTCTGCATCAACGCCAATAAACATGTTGCTTAATAATAATGGATTGGCGTGGTTCTTCCCCAGGATACCTTATAGAGTCTAG
TGAACTTTTCCTGTTTGTGGAAACAATCAGGCTGGGTTTAAATGAGGACTTGTCTCTATTTGGAGCATTTGTGAGCGTGTAAGGAAATGA

>83311_83311_4_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370859_PLEKHA7_chr11_16812752_ENST00000355661_length(amino acids)=209AA_BP=2
MTQEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDRELGQCVNGDSRVELRSYVSEPELATLSGDMAQPSL
GLVGPESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAESSKATFPRPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERK

--------------------------------------------------------------
>83311_83311_5_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370859_PLEKHA7_chr11_16812752_ENST00000448080_length(transcript)=2202nt_BP=159nt
ACAGTAGTGAATCGTAGCATGTTAGAGTTAGAAGGTTCAGTGTTGATGGAGTTATTGAAGAAATGATGGAGTAAGAGACTCTTTTCTAAG
CAACTCAAGTTTGCAGTGATTCAGGCCTACTTCTGAAGAGACAGCCTTTTATCTCAATGAATGACACAGCAGGAAGATGAAGCACCTCCC
AGGCCCCCACTCCCCGAACTCTACAGCCCAGAGGACCAGCCCCCGGCTGTGCCGCCTCTGCCAAGAGAGGCCACCATCATCCGGCACACA
TCTGTGCGGGGCCTCAAGCGGCAGTCAGACGAGAGGAAGCGAGACCGGGAGCTGGGGCAGTGTGTGAATGGGGATTCCAGGGTGGAGCTG
CGGTCGTATGTCAGTGAGCCTGAGCTGGCGACCCTCAGCGGGGACATGGCCCAGCCCTCCCTAGGACTTGTGGGCCCTGAGAGCAGGTAC
CAGACGCTGCCAGGCAGAGGGCTCTCAGGGTCCACGTCAAGGCTCCAGCAGTCGTCCACCATTGCTCCCTACGTCACACTCCGGAGGGGT
CTCAATGCCGAAAGCAGCAAGGCGACCTTCCCTAGACCTAAGAGTGCCTTGGAGCGCCTGTACTCAGGGGATCACCAGCGAGGCAAGATG
AGTGCAGAGGAGCAGCTGGAGCGCATGAAGCGACACCAGAAGGCCCTGGTCCGAGAGCGCAAGAGGACACTGGGCCAAGGGGAGAGGACG
GGCCTGCCCTCATCTCGCTACCTCAGCCGGCCGCTCCCTGGAGATCTTGGCTCAGTATGTTAGGAGGGGCCAGGCAGCGGGGCAGGGACA
GGGAGCCGAGTGCCCCTCAGAGTCCCCCAAACACAAGCACATCACACCTCCCAGTGAGAGAGCTGTCCATTGACCTACATGGTTCAGAGA
ACACCCCACGGGGCTGTTTGTCCACGACCCAGGCTGGACGAATGCCTGGTCAGAGGGTGACCTGAACCAGAGCTGGAGTGAGGATCAAAC
AGGCCCAGGAGCCTGAGGAAATACCCAGTCAGTCCTCCCAGCCGCGATGGAGAGGGGCCTTTGCAGGCGTTCGGAATCTCGGCTGAATTC
AGGACCTGGGAATACAGGGTTCAGAGAGGAGAGGAGGAAGATGGTGACATGATTTGGTTAGAAGCACAAGCAAACTGATCAGCCTCCCAG
ACCTGCCAGCAGATGCTGTGTGAGGGTGATGGAGCACGGGGTCACACCCCTGCCCCAAGGGCCACTGGTCTCCCTGGGCTTGCAGTGCAG
AGGCCTCAGGGTGTCTGGGATTGCTGGGGAGGCCTGTGCTGCCCCCTGGTGGCGCTTCCTGGCGCTGCGCCCTGTCCACAGTCACCTTAG
GTCCCTTTGGAAACATTCCATTTGACTTTTCCCTGTTGTTTGAAATCCCATGTTTCCCTAAACCTCTAGCCTGATTGTTCTTTCCCTAAT
TCATTGCACAAGCTCCTTTGCTTTTAGTGTTACCGCTCATTGCCTCTCTAATCCTGCCTGATTGTGTTTACAGAAGCTTCTGATTTGCAT
TGAACATGCTCTAACTGGCCTGTGCTACTTATTACCGGGCTTGTAATAGCGGTTCTTGTCTCCATAGCCTGTTGAGTGTTCCCAGATGTG
ACTCACCTTTCTGCTGCCCTCTTCATGCAGGCCTACTGACTCATAATTCACTTGTCCCAAAAGCCACCCCACAAGCCTGAGCCAACCTGC
TGCCTGACGCCACAGTCATTGGCAGAGGTCTGGGCATTATTAATTTATAAAAATCCATGCTTTACACCTGGACAGTAGACAGGGACTTCA
GAGATTGCACGTTTGAATACATTCTCCCAAGACTGAGGTTGTTCGGTTTTAATTCCTGTAGTCCAATCACACAATTTCTTATGGAAAACC
TTTTGTGTTTCTGGTATTTAATAACTTGAAGGGATAGCAAAATATACTGTGTATTCAGAGGGCCTCTCTGCAGCTGCTAGCTCAGACACC
AAAGGGGTAAGGCCCAGGACATTCATATCTTTAAAAGCTGCAAACCTGGTAACCTTTAAACTTTTAAAACAAATGTCATATGGGGTAACA
CTGACCTTTTATAATTTGATGTCTCAAATGTAGAGATTATCTAAAAATCGTAACTTGAATACCTTGTAATTTTTCTCTTAAAAAAGAAGA

>83311_83311_5_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370859_PLEKHA7_chr11_16812752_ENST00000448080_length(amino acids)=210AA_BP=2
MTQQEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDRELGQCVNGDSRVELRSYVSEPELATLSGDMAQPS
LGLVGPESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAESSKATFPRPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRER

--------------------------------------------------------------
>83311_83311_6_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370859_PLEKHA7_chr11_16812752_ENST00000531066_length(transcript)=1933nt_BP=159nt
ACAGTAGTGAATCGTAGCATGTTAGAGTTAGAAGGTTCAGTGTTGATGGAGTTATTGAAGAAATGATGGAGTAAGAGACTCTTTTCTAAG
CAACTCAAGTTTGCAGTGATTCAGGCCTACTTCTGAAGAGACAGCCTTTTATCTCAATGAATGACACAGGAAGATGAAGCACCTCCCAGG
CCCCCACTCCCCGAACTCTACAGCCCAGAGGACCAGCCCCCGGCTGTGCCGCCTCTGCCAAGAGAGGCCACCATCATCCGGCACACATCT
GTGCGGGGCCTCAAGCGGCAGTCAGACGAGAGGAAGCGAGACCGGGAGCTGGGGCAGTGTGTGAATGGGGATTCCAGGGTGGAGCTGCGG
TCGTATGTCAGTGAGCCTGAGCTGGCGACCCTCAGCGGGGACATGGCCCAGCCCTCCCTAGGACTTGTGGGCCCTGAGAGCAGGTACCAG
ACGCTGCCAGGCAGAGGGCTCTCAGGGTCCACGTCAAGGCTCCAGCAGTCGTCCACCATTGCTCCCTACGTCACACTCCGGAGGGGTCTC
AATGCCGAAAGCAGCAAGGCGACCTTCCCTAGACCTAAGAGTGCCTTGGAGCGCCTGTACTCAGGGGATCACCAGCGAGGCAAGATGAGT
GCAGAGGAGCAGCTGGAGCGCATGAAGCGACACCAGAAGGCCCTGGTCCGAGAGCGCAAGAGGACACTGGGCCAAGGGGAGAGGACGGGC
CTGCCCTCATCTCGCTACCTCAGCCGGCCGCTCCCTGGAGATCTTGGCTCATGGAAGCGTGAGCAGGACTTTGACCTGCAGTTGCTGGAA
CGGGTCGTGCAAGGGGAAAAAAAGGACAAGGAGGAGAATGGCTGGTTGAAAGTGCAGGCCATGCCTGTCACTGAGTTGGACCTGGAGCCT
CAAGACTATGACTTGGACATCAGCAGAGAGCTGTCCAAACCAGAGAAGGTGTCAATCCCTGAGCGCTACGTGGAGCTAGATCCCGAAGAG
CCACCCAGCCTTGAGGAGCTGCAGGCGCGGTACCGCAAAGCCGAGAAGATCCGCAACATCCTCGCCCGGTCAAGCATGTGCAACCTACAG
CCGACCTCAGGCCAGGACCAGAACAGTGTGGCTGACCTGGACTTGCAGCTGCAGGAGCAGGAGCGCATCATCAACATCTCCTACGCCCTG
GCCTCCGAGGCCTCCCAGCGTAGCAAGCAGGTGGCAGCCCAGGCAGTGACTGACCCGTGACCCAGCATGCAAAGAAGCCTGGAGCCAGGG
GCCCAGTGGAACCAGCTTCCTCCAAGGAGATGACCTTTCTGCCCCCAAGGAAACCCCTTCCAGCTGAGCAGGGAATCCGGCCGGAGGAAG
GAGCAGCTTACCGACTGCGGGTGTTCACCACAGGCCAGGCCCTAATATGCACCCACTAGTTTAGCTCAGACTCCTCTCTACATATGAATG
GCAAAGGCACTTTTGATATACACTGTAAAATACACTGTATTTTAGAATCGGAATCTATTTTCTAATGTTCCCCTCAAGGGCTGAGTGGCA
GGAAGGTTGAGGATGCAGGACTTTGCAGCTGCACGTACAGATTCAGGTACTTCTGGGTGACAGGTGTTGTGGGGGCAGGAAGGGCGGGGC
AAGCCGAGGCTAGTCCAACTTCCAATGACCTCAGGAGAAAGTGAGATTTAAAGAGGTGTTCCCAGTAGACTCCAGCAAGAGGCTGGTTGG
CGTGCTGTCTGGGAGAAGAGGGGCCCTTGGCTGCAGAGATCAGCTGTCCCTGACCTGATGACCAGCTCTGTGTGAAACTCCACGAGGATC
ACACGTGGAGCCCAAGTCTGTGCCTTGCCCCTTGGGTTTGGCTTAGGGGCAACAGTGTGTTCAAGAGGACTGGGGCCCACAACCTGCCCC

>83311_83311_6_SLC44A5-PLEKHA7_SLC44A5_chr1_76007120_ENST00000370859_PLEKHA7_chr11_16812752_ENST00000531066_length(amino acids)=359AA_BP=2
MTQEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDRELGQCVNGDSRVELRSYVSEPELATLSGDMAQPSL
GLVGPESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAESSKATFPRPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERK
RTLGQGERTGLPSSRYLSRPLPGDLGSWKREQDFDLQLLERVVQGEKKDKEENGWLKVQAMPVTELDLEPQDYDLDISRELSKPEKVSIP

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SLC44A5-PLEKHA7

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Tgene	PLEKHA7	chr1:76007120	chr11:16812752	ENST00000355661		18	23	538_696	915.0	1122.0	CTNND1
Tgene	PLEKHA7	chr1:76007120	chr11:16812752	ENST00000448080		18	23	538_696	915.0	1123.0	CTNND1

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for SLC44A5-PLEKHA7

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for SLC44A5-PLEKHA7

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source