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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ATR-R3HDM2 (FusionGDB2 ID:8339)

Fusion Gene Summary for ATR-R3HDM2

check button Fusion gene summary
Fusion gene informationFusion gene name: ATR-R3HDM2
Fusion gene ID: 8339
HgeneTgene
Gene symbol

ATR

R3HDM2

Gene ID

390502

22864

Gene nameserpin family A member 2 (gene/pseudogene)R3H domain containing 2
SynonymsARGS|ATR|PIL|SERPINA2P|psiATRCAG6|PR01365
Cytomap

14q32.13

12q13.3

Type of geneprotein-codingprotein-coding
Descriptionputative alpha-1-antitrypsin-related proteinserine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2serpin A2serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2, pseudogeneR3H domain-containing protein 2
Modification date2020031320200320
UniProtAcc

Q13535

.
Ensembl transtripts involved in fusion geneENST00000350721, ENST00000383101, 
ENST00000546843, ENST00000347140, 
ENST00000358907, ENST00000402412, 
ENST00000403821, ENST00000413953, 
ENST00000441731, 
Fusion gene scores* DoF score8 X 6 X 6=28812 X 12 X 7=1008
# samples 1014
** MAII scorelog2(10/288*10)=-1.52606881166759
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1008*10)=-2.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATR [Title/Abstract] AND R3HDM2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATR(142284963)-R3HDM2(57650294), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ATR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across R3HDM2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-VQ-AA6D-01AATRchr3

142284963

-R3HDM2chr12

57650294

-
ChimerDB4STADTCGA-VQ-AA6DATRchr3

142284962

-R3HDM2chr12

57650294

-


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Fusion Gene ORF analysis for ATR-R3HDM2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000350721ENST00000546843ATRchr3

142284963

-R3HDM2chr12

57650294

-
5CDS-intronENST00000350721ENST00000546843ATRchr3

142284962

-R3HDM2chr12

57650294

-
5CDS-intronENST00000383101ENST00000546843ATRchr3

142284963

-R3HDM2chr12

57650294

-
5CDS-intronENST00000383101ENST00000546843ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000347140ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000347140ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000358907ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000358907ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000402412ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000402412ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000403821ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000403821ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000413953ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000413953ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000441731ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000350721ENST00000441731ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000347140ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000347140ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000358907ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000358907ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000402412ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000402412ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000403821ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000403821ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000413953ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000413953ATRchr3

142284962

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000441731ATRchr3

142284963

-R3HDM2chr12

57650294

-
In-frameENST00000383101ENST00000441731ATRchr3

142284962

-R3HDM2chr12

57650294

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000350721ATRchr3142284963-ENST00000413953R3HDM2chr1257650294-827414122616164
ENST00000350721ATRchr3142284963-ENST00000347140R3HDM2chr1257650294-1947414122937271
ENST00000350721ATRchr3142284963-ENST00000358907R3HDM2chr1257650294-1946414122937271
ENST00000350721ATRchr3142284963-ENST00000402412R3HDM2chr1257650294-1946414122937271
ENST00000350721ATRchr3142284963-ENST00000441731R3HDM2chr1257650294-986414122937271
ENST00000350721ATRchr3142284963-ENST00000403821R3HDM2chr1257650294-955414122937271
ENST00000383101ATRchr3142284963-ENST00000413953R3HDM2chr1257650294-827414122616164
ENST00000383101ATRchr3142284963-ENST00000347140R3HDM2chr1257650294-1947414122937271
ENST00000383101ATRchr3142284963-ENST00000358907R3HDM2chr1257650294-1946414122937271
ENST00000383101ATRchr3142284963-ENST00000402412R3HDM2chr1257650294-1946414122937271
ENST00000383101ATRchr3142284963-ENST00000441731R3HDM2chr1257650294-986414122937271
ENST00000383101ATRchr3142284963-ENST00000403821R3HDM2chr1257650294-955414122937271
ENST00000350721ATRchr3142284962-ENST00000413953R3HDM2chr1257650294-827414122616164
ENST00000350721ATRchr3142284962-ENST00000347140R3HDM2chr1257650294-1947414122937271
ENST00000350721ATRchr3142284962-ENST00000358907R3HDM2chr1257650294-1946414122937271
ENST00000350721ATRchr3142284962-ENST00000402412R3HDM2chr1257650294-1946414122937271
ENST00000350721ATRchr3142284962-ENST00000441731R3HDM2chr1257650294-986414122937271
ENST00000350721ATRchr3142284962-ENST00000403821R3HDM2chr1257650294-955414122937271
ENST00000383101ATRchr3142284962-ENST00000413953R3HDM2chr1257650294-827414122616164
ENST00000383101ATRchr3142284962-ENST00000347140R3HDM2chr1257650294-1947414122937271
ENST00000383101ATRchr3142284962-ENST00000358907R3HDM2chr1257650294-1946414122937271
ENST00000383101ATRchr3142284962-ENST00000402412R3HDM2chr1257650294-1946414122937271
ENST00000383101ATRchr3142284962-ENST00000441731R3HDM2chr1257650294-986414122937271
ENST00000383101ATRchr3142284962-ENST00000403821R3HDM2chr1257650294-955414122937271

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000350721ENST00000413953ATRchr3142284963-R3HDM2chr1257650294-0.0045679890.995432
ENST00000350721ENST00000347140ATRchr3142284963-R3HDM2chr1257650294-0.0011697870.99883026
ENST00000350721ENST00000358907ATRchr3142284963-R3HDM2chr1257650294-0.0011625760.9988374
ENST00000350721ENST00000402412ATRchr3142284963-R3HDM2chr1257650294-0.0011625760.9988374
ENST00000350721ENST00000441731ATRchr3142284963-R3HDM2chr1257650294-0.0025322490.99746776
ENST00000350721ENST00000403821ATRchr3142284963-R3HDM2chr1257650294-0.0023221170.99767786
ENST00000383101ENST00000413953ATRchr3142284963-R3HDM2chr1257650294-0.0045679890.995432
ENST00000383101ENST00000347140ATRchr3142284963-R3HDM2chr1257650294-0.0011697870.99883026
ENST00000383101ENST00000358907ATRchr3142284963-R3HDM2chr1257650294-0.0011625760.9988374
ENST00000383101ENST00000402412ATRchr3142284963-R3HDM2chr1257650294-0.0011625760.9988374
ENST00000383101ENST00000441731ATRchr3142284963-R3HDM2chr1257650294-0.0025322490.99746776
ENST00000383101ENST00000403821ATRchr3142284963-R3HDM2chr1257650294-0.0023221170.99767786
ENST00000350721ENST00000413953ATRchr3142284962-R3HDM2chr1257650294-0.0045679890.995432
ENST00000350721ENST00000347140ATRchr3142284962-R3HDM2chr1257650294-0.0011697870.99883026
ENST00000350721ENST00000358907ATRchr3142284962-R3HDM2chr1257650294-0.0011625760.9988374
ENST00000350721ENST00000402412ATRchr3142284962-R3HDM2chr1257650294-0.0011625760.9988374
ENST00000350721ENST00000441731ATRchr3142284962-R3HDM2chr1257650294-0.0025322490.99746776
ENST00000350721ENST00000403821ATRchr3142284962-R3HDM2chr1257650294-0.0023221170.99767786
ENST00000383101ENST00000413953ATRchr3142284962-R3HDM2chr1257650294-0.0045679890.995432
ENST00000383101ENST00000347140ATRchr3142284962-R3HDM2chr1257650294-0.0011697870.99883026
ENST00000383101ENST00000358907ATRchr3142284962-R3HDM2chr1257650294-0.0011625760.9988374
ENST00000383101ENST00000402412ATRchr3142284962-R3HDM2chr1257650294-0.0011625760.9988374
ENST00000383101ENST00000441731ATRchr3142284962-R3HDM2chr1257650294-0.0025322490.99746776
ENST00000383101ENST00000403821ATRchr3142284962-R3HDM2chr1257650294-0.0023221170.99767786

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Fusion Genomic Features for ATR-R3HDM2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ATR-R3HDM2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:142284963/chr12:57650294)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATR

Q13535

.
FUNCTION: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates BRCA1, CHEK1, MCM2, RAD17, RPA2, SMC1 and p53/TP53, which collectively inhibit DNA replication and mitosis and promote DNA repair, recombination and apoptosis. Phosphorylates 'Ser-139' of histone variant H2AX at sites of DNA damage, thereby regulating DNA damage response mechanism. Required for FANCD2 ubiquitination. Critical for maintenance of fragile site stability and efficient regulation of centrosome duplication. Positively regulates the restart of stalled replication forks following activation by the KHDC3L-OOEP scaffold complex (By similarity). {ECO:0000250|UniProtKB:Q9JKK8, ECO:0000269|PubMed:10597277, ECO:0000269|PubMed:10608806, ECO:0000269|PubMed:10859164, ECO:0000269|PubMed:11114888, ECO:0000269|PubMed:11418864, ECO:0000269|PubMed:11673449, ECO:0000269|PubMed:11721054, ECO:0000269|PubMed:11865061, ECO:0000269|PubMed:12526805, ECO:0000269|PubMed:12791985, ECO:0000269|PubMed:12814551, ECO:0000269|PubMed:14657349, ECO:0000269|PubMed:14729973, ECO:0000269|PubMed:14742437, ECO:0000269|PubMed:15210935, ECO:0000269|PubMed:15314022, ECO:0000269|PubMed:15496423, ECO:0000269|PubMed:16260606, ECO:0000269|PubMed:21144835, ECO:0000269|PubMed:27723717, ECO:0000269|PubMed:27723720, ECO:0000269|PubMed:9427750, ECO:0000269|PubMed:9636169, ECO:0000269|PubMed:9925639}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneR3HDM2chr3:142284962chr12:57650294ENST000003471402024908_912802977.0Compositional biasNote=Poly-Gly
TgeneR3HDM2chr3:142284962chr12:57650294ENST000003589071822908_912802977.0Compositional biasNote=Poly-Gly
TgeneR3HDM2chr3:142284963chr12:57650294ENST000003471402024908_912802977.0Compositional biasNote=Poly-Gly
TgeneR3HDM2chr3:142284963chr12:57650294ENST000003589071822908_912802977.0Compositional biasNote=Poly-Gly

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATRchr3:142284962chr12:57650294ENST00000350721-3471640_2185972645.0DomainFAT
HgeneATRchr3:142284962chr12:57650294ENST00000350721-3472322_2567972645.0DomainPI3K/PI4K
HgeneATRchr3:142284962chr12:57650294ENST00000350721-3472612_2644972645.0DomainFATC
HgeneATRchr3:142284962chr12:57650294ENST00000383101-3461640_2185972581.0DomainFAT
HgeneATRchr3:142284962chr12:57650294ENST00000383101-3462322_2567972581.0DomainPI3K/PI4K
HgeneATRchr3:142284962chr12:57650294ENST00000383101-3462612_2644972581.0DomainFATC
HgeneATRchr3:142284963chr12:57650294ENST00000350721-3471640_2185972645.0DomainFAT
HgeneATRchr3:142284963chr12:57650294ENST00000350721-3472322_2567972645.0DomainPI3K/PI4K
HgeneATRchr3:142284963chr12:57650294ENST00000350721-3472612_2644972645.0DomainFATC
HgeneATRchr3:142284963chr12:57650294ENST00000383101-3461640_2185972581.0DomainFAT
HgeneATRchr3:142284963chr12:57650294ENST00000383101-3462322_2567972581.0DomainPI3K/PI4K
HgeneATRchr3:142284963chr12:57650294ENST00000383101-3462612_2644972581.0DomainFATC
HgeneATRchr3:142284962chr12:57650294ENST00000350721-3471329_1365972645.0RepeatNote=HEAT 2
HgeneATRchr3:142284962chr12:57650294ENST00000350721-347799_835972645.0RepeatNote=HEAT 1
HgeneATRchr3:142284962chr12:57650294ENST00000383101-3461329_1365972581.0RepeatNote=HEAT 2
HgeneATRchr3:142284962chr12:57650294ENST00000383101-346799_835972581.0RepeatNote=HEAT 1
HgeneATRchr3:142284963chr12:57650294ENST00000350721-3471329_1365972645.0RepeatNote=HEAT 2
HgeneATRchr3:142284963chr12:57650294ENST00000350721-347799_835972645.0RepeatNote=HEAT 1
HgeneATRchr3:142284963chr12:57650294ENST00000383101-3461329_1365972581.0RepeatNote=HEAT 2
HgeneATRchr3:142284963chr12:57650294ENST00000383101-346799_835972581.0RepeatNote=HEAT 1
TgeneR3HDM2chr3:142284962chr12:57650294ENST000003471402024288_369802977.0Compositional biasNote=Ser-rich
TgeneR3HDM2chr3:142284962chr12:57650294ENST000003471402024404_694802977.0Compositional biasNote=Gln-rich
TgeneR3HDM2chr3:142284962chr12:57650294ENST000003589071822288_369802977.0Compositional biasNote=Ser-rich
TgeneR3HDM2chr3:142284962chr12:57650294ENST000003589071822404_694802977.0Compositional biasNote=Gln-rich
TgeneR3HDM2chr3:142284963chr12:57650294ENST000003471402024288_369802977.0Compositional biasNote=Ser-rich
TgeneR3HDM2chr3:142284963chr12:57650294ENST000003471402024404_694802977.0Compositional biasNote=Gln-rich
TgeneR3HDM2chr3:142284963chr12:57650294ENST000003589071822288_369802977.0Compositional biasNote=Ser-rich
TgeneR3HDM2chr3:142284963chr12:57650294ENST000003589071822404_694802977.0Compositional biasNote=Gln-rich
TgeneR3HDM2chr3:142284962chr12:57650294ENST000003471402024169_232802977.0DomainR3H
TgeneR3HDM2chr3:142284962chr12:57650294ENST000003471402024233_310802977.0DomainSUZ
TgeneR3HDM2chr3:142284962chr12:57650294ENST000003589071822169_232802977.0DomainR3H
TgeneR3HDM2chr3:142284962chr12:57650294ENST000003589071822233_310802977.0DomainSUZ
TgeneR3HDM2chr3:142284963chr12:57650294ENST000003471402024169_232802977.0DomainR3H
TgeneR3HDM2chr3:142284963chr12:57650294ENST000003471402024233_310802977.0DomainSUZ
TgeneR3HDM2chr3:142284963chr12:57650294ENST000003589071822169_232802977.0DomainR3H
TgeneR3HDM2chr3:142284963chr12:57650294ENST000003589071822233_310802977.0DomainSUZ


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Fusion Gene Sequence for ATR-R3HDM2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8339_8339_1_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000347140_length(transcript)=1947nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_1_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000347140_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_2_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000358907_length(transcript)=1946nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_2_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000358907_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_3_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000402412_length(transcript)=1946nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_3_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000402412_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_4_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000403821_length(transcript)=955nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT

>8339_8339_4_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000403821_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_5_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000413953_length(transcript)=827nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGCCCTGTCATTTCAGCCCTGACACCAAGGCAGGA
GGCTAGGAGGTCTACAAATAGCGACTGGGTAGCTGGTGTGAACACAGGGGGTACTGGGGGGGCTTAGCCCCCAAGGAAGAGGACCAGTTT
TTCCCCAGCACCACCATCAAGGCCTCGAGGCTCCCAGCTCCCTCTACAGCCTGTGGACTGACTTAGGGAATCCCGAACGATGACAGAAAA

>8339_8339_5_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000413953_length(amino acids)=164AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH

--------------------------------------------------------------
>8339_8339_6_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000441731_length(transcript)=986nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT

>8339_8339_6_ATR-R3HDM2_ATR_chr3_142284962_ENST00000350721_R3HDM2_chr12_57650294_ENST00000441731_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_7_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000347140_length(transcript)=1947nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_7_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000347140_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_8_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000358907_length(transcript)=1946nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_8_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000358907_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_9_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000402412_length(transcript)=1946nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_9_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000402412_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_10_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000403821_length(transcript)=955nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT

>8339_8339_10_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000403821_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_11_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000413953_length(transcript)=827nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGCCCTGTCATTTCAGCCCTGACACCAAGGCAGGA
GGCTAGGAGGTCTACAAATAGCGACTGGGTAGCTGGTGTGAACACAGGGGGTACTGGGGGGGCTTAGCCCCCAAGGAAGAGGACCAGTTT
TTCCCCAGCACCACCATCAAGGCCTCGAGGCTCCCAGCTCCCTCTACAGCCTGTGGACTGACTTAGGGAATCCCGAACGATGACAGAAAA

>8339_8339_11_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000413953_length(amino acids)=164AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH

--------------------------------------------------------------
>8339_8339_12_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000441731_length(transcript)=986nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT

>8339_8339_12_ATR-R3HDM2_ATR_chr3_142284962_ENST00000383101_R3HDM2_chr12_57650294_ENST00000441731_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_13_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000347140_length(transcript)=1947nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_13_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000347140_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_14_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000358907_length(transcript)=1946nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_14_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000358907_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_15_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000402412_length(transcript)=1946nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_15_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000402412_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_16_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000403821_length(transcript)=955nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT

>8339_8339_16_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000403821_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_17_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000413953_length(transcript)=827nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGCCCTGTCATTTCAGCCCTGACACCAAGGCAGGA
GGCTAGGAGGTCTACAAATAGCGACTGGGTAGCTGGTGTGAACACAGGGGGTACTGGGGGGGCTTAGCCCCCAAGGAAGAGGACCAGTTT
TTCCCCAGCACCACCATCAAGGCCTCGAGGCTCCCAGCTCCCTCTACAGCCTGTGGACTGACTTAGGGAATCCCGAACGATGACAGAAAA

>8339_8339_17_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000413953_length(amino acids)=164AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH

--------------------------------------------------------------
>8339_8339_18_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000441731_length(transcript)=986nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT

>8339_8339_18_ATR-R3HDM2_ATR_chr3_142284963_ENST00000350721_R3HDM2_chr12_57650294_ENST00000441731_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_19_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000347140_length(transcript)=1947nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_19_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000347140_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_20_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000358907_length(transcript)=1946nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_20_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000358907_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_21_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000402412_length(transcript)=1946nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT
ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG
GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA
CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT
TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT
TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG
CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG
CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT
ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT
TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC
TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA
CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT

>8339_8339_21_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000402412_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_22_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000403821_length(transcript)=955nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT

>8339_8339_22_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000403821_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------
>8339_8339_23_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000413953_length(transcript)=827nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGCCCTGTCATTTCAGCCCTGACACCAAGGCAGGA
GGCTAGGAGGTCTACAAATAGCGACTGGGTAGCTGGTGTGAACACAGGGGGTACTGGGGGGGCTTAGCCCCCAAGGAAGAGGACCAGTTT
TTCCCCAGCACCACCATCAAGGCCTCGAGGCTCCCAGCTCCCTCTACAGCCTGTGGACTGACTTAGGGAATCCCGAACGATGACAGAAAA

>8339_8339_23_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000413953_length(amino acids)=164AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH

--------------------------------------------------------------
>8339_8339_24_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000441731_length(transcript)=986nt_BP=414nt
TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT
GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA
GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG
TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC
CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC
AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC
GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC
CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG
GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG
TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT

>8339_8339_24_ATR-R3HDM2_ATR_chr3_142284963_ENST00000383101_R3HDM2_chr12_57650294_ENST00000441731_length(amino acids)=271AA_BP=97
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH
EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK
LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ATR-R3HDM2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATR-R3HDM2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATR-R3HDM2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource