Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SLC5A1-PIGR (FusionGDB2 ID:83414)

Fusion Gene Summary for SLC5A1-PIGR

Fusion gene summary

Fusion gene information	Fusion gene name: SLC5A1-PIGR
	Fusion gene ID: 83414
		Hgene	Tgene
	Gene symbol	SLC5A1	PIGR
	Gene ID	6523	5284
	Gene name	solute carrier family 5 member 1	polymeric immunoglobulin receptor
	Synonyms	D22S675\|NAGT\|SGLT1	-
	Cytomap	22q12.3	1q32.1
	Type of gene	protein-coding	protein-coding
	Description	sodium/glucose cotransporter 1Na+/glucose cotransporter 1high affinity sodium-glucose cotransportersolute carrier family 5 (sodium/glucose cotransporter), member 1	polymeric immunoglobulin receptorhepatocellular carcinoma associated protein TB6poly-Ig receptor
	Modification date	20200313	20200329
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000266088, ENST00000543737,	ENST00000487208, ENST00000356495,
Fusion gene scores	* DoF score	6 X 8 X 3=144	20 X 21 X 5=2100
	# samples	9	23
	** MAII score	log2(9/144*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(23/2100*10)=-3.19068356160911 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SLC5A1 [Title/Abstract] AND PIGR [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SLC5A1(32495338)-PIGR(207119811), # samples:1 SLC5A1(32495342)-PIGR(207119808), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	SLC5A1	GO:1904659	glucose transmembrane transport	8836035
Tgene	PIGR	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste	24248522
Tgene	PIGR	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor	22022593
Tgene	PIGR	GO:0007173	epidermal growth factor receptor signaling pathway	22022593
Tgene	PIGR	GO:0038093	Fc receptor signaling pathway	22022593
Tgene	PIGR	GO:0043113	receptor clustering	22022593

Fusion gene breakpoints across SLC5A1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PIGR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-D7-8574-01A	SLC5A1	chr22	32495342	+	PIGR	chr1	207119808	-
ChimerDB4	STAD	TCGA-D7-8574	SLC5A1	chr22	32495338	+	PIGR	chr1	207119811	-

Top

Fusion Gene ORF analysis for SLC5A1-PIGR

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000266088	ENST00000487208	SLC5A1	chr22	32495342	+	PIGR	chr1	207119808	-
5CDS-intron	ENST00000266088	ENST00000487208	SLC5A1	chr22	32495338	+	PIGR	chr1	207119811	-
5CDS-intron	ENST00000543737	ENST00000487208	SLC5A1	chr22	32495342	+	PIGR	chr1	207119808	-
5CDS-intron	ENST00000543737	ENST00000487208	SLC5A1	chr22	32495338	+	PIGR	chr1	207119811	-
In-frame	ENST00000266088	ENST00000356495	SLC5A1	chr22	32495342	+	PIGR	chr1	207119808	-
In-frame	ENST00000266088	ENST00000356495	SLC5A1	chr22	32495338	+	PIGR	chr1	207119811	-
In-frame	ENST00000543737	ENST00000356495	SLC5A1	chr22	32495342	+	PIGR	chr1	207119808	-
In-frame	ENST00000543737	ENST00000356495	SLC5A1	chr22	32495338	+	PIGR	chr1	207119811	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000266088	SLC5A1	chr22	32495338	+	ENST00000356495	PIGR	chr1	207119811	-	5978	1699	1550	4177	875
ENST00000543737	SLC5A1	chr22	32495338	+	ENST00000356495	PIGR	chr1	207119811	-	5675	1396	1247	3874	875
ENST00000266088	SLC5A1	chr22	32495342	+	ENST00000356495	PIGR	chr1	207119808	-	5978	1699	1550	4177	875
ENST00000543737	SLC5A1	chr22	32495342	+	ENST00000356495	PIGR	chr1	207119808	-	5675	1396	1247	3874	875

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000266088	ENST00000356495	SLC5A1	chr22	32495338	+	PIGR	chr1	207119811	-	0.002997204	0.9970028
ENST00000543737	ENST00000356495	SLC5A1	chr22	32495338	+	PIGR	chr1	207119811	-	0.002312952	0.9976871
ENST00000266088	ENST00000356495	SLC5A1	chr22	32495342	+	PIGR	chr1	207119808	-	0.002997204	0.9970028
ENST00000543737	ENST00000356495	SLC5A1	chr22	32495342	+	PIGR	chr1	207119808	-	0.002312952	0.9976871

Top

Fusion Genomic Features for SLC5A1-PIGR

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for SLC5A1-PIGR

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:32495338/chr1:207119811)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

127_142

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

164_178

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

1_28

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

202_208

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

230_277

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

299_313

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

335_380

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

402_423

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

445_455

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

477_484

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

50_64

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

86_105

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

127_142

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

164_178

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

1_28

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

202_208

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

230_277

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

299_313

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

50_64

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

86_105

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

127_142

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

164_178

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

1_28

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

202_208

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

230_277

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

299_313

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

335_380

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

402_423

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

445_455

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

477_484

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

50_64

483

665.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

86_105

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

127_142

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

164_178

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

1_28

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

202_208

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

230_277

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

299_313

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

50_64

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

86_105

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

106_126

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

143_163

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

179_201

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

209_229

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

278_298

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

29_49

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

314_334

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

381_401

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

424_444

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

456_476

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

65_85

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

106_126

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

143_163

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

179_201

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

209_229

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

278_298

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

29_49

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

314_334

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

65_85

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

106_126

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

143_163

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

179_201

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

209_229

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

278_298

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

29_49

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

314_334

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

381_401

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

424_444

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

456_476

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

65_85

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

106_126

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

143_163

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

179_201

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

209_229

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

278_298

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

29_49

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

314_334

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

65_85

356

538.0

Transmembrane

Helical

Tgene

PIGR

chr22:32495338

chr1:207119811

ENST00000356495

-1

145_237

765.0

Domain

Note=Ig-like V-type 2

Tgene

PIGR

chr22:32495338

chr1:207119811

ENST00000356495

-1

19_120

765.0

Domain

Ig-like V-type 1%3B required for binding to polymeric IgA and IgM

Tgene

PIGR

chr22:32495338

chr1:207119811

ENST00000356495

-1

250_352

765.0

Domain

Note=Ig-like V-type 3

Tgene

PIGR

chr22:32495338

chr1:207119811

ENST00000356495

-1

364_458

765.0

Domain

Note=Ig-like V-type 4

Tgene

PIGR

chr22:32495338

chr1:207119811

ENST00000356495

-1

462_561

765.0

Domain

Note=Ig-like V-type 5

Tgene

PIGR

chr22:32495342

chr1:207119808

ENST00000356495

-1

145_237

765.0

Domain

Note=Ig-like V-type 2

Tgene

PIGR

chr22:32495342

chr1:207119808

ENST00000356495

-1

19_120

765.0

Domain

Ig-like V-type 1%3B required for binding to polymeric IgA and IgM

Tgene

PIGR

chr22:32495342

chr1:207119808

ENST00000356495

-1

250_352

765.0

Domain

Note=Ig-like V-type 3

Tgene

PIGR

chr22:32495342

chr1:207119808

ENST00000356495

-1

364_458

765.0

Domain

Note=Ig-like V-type 4

Tgene

PIGR

chr22:32495342

chr1:207119808

ENST00000356495

-1

462_561

765.0

Domain

Note=Ig-like V-type 5

Tgene

PIGR

chr22:32495338

chr1:207119811

ENST00000356495

-1

19_638

765.0

Topological domain

Extracellular

Tgene

PIGR

chr22:32495338

chr1:207119811

ENST00000356495

-1

662_764

765.0

Topological domain

Cytoplasmic

Tgene

PIGR

chr22:32495342

chr1:207119808

ENST00000356495

-1

19_638

765.0

Topological domain

Extracellular

Tgene

PIGR

chr22:32495342

chr1:207119808

ENST00000356495

-1

662_764

765.0

Topological domain

Cytoplasmic

Tgene

PIGR

chr22:32495338

chr1:207119811

ENST00000356495

-1

639_661

765.0

Transmembrane

Helical

Tgene

PIGR

chr22:32495342

chr1:207119808

ENST00000356495

-1

639_661

765.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

527_563

483

665.0

Intramembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

527_563

356

538.0

Intramembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

527_563

483

665.0

Intramembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

527_563

356

538.0

Intramembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

506_526

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

564_643

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

335_380

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

402_423

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

445_455

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

477_484

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

506_526

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

564_643

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

506_526

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

564_643

483

665.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

335_380

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

402_423

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

445_455

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

477_484

356

538.0

Topological domain

Cytoplasmic

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

506_526

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

564_643

356

538.0

Topological domain

Extracellular

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

485_505

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000266088

644_664

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

381_401

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

424_444

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

456_476

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

485_505

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495338

chr1:207119811

ENST00000543737

644_664

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

485_505

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000266088

644_664

483

665.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

381_401

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

424_444

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

456_476

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

485_505

356

538.0

Transmembrane

Helical

Hgene

SLC5A1

chr22:32495342

chr1:207119808

ENST00000543737

644_664

356

538.0

Transmembrane

Helical

Top

Fusion Gene Sequence for SLC5A1-PIGR

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>83414_83414_1_SLC5A1-PIGR_SLC5A1_chr22_32495338_ENST00000266088_PIGR_chr1_207119811_ENST00000356495_length(transcript)=5978nt_BP=1699nt
CCCCATTCGCAGGACAGCTCTTACCTGCCGGGCCGCCGCCCCAGCCAACAGCTCAGCCGGGTGCTCCTTCCTGGGCTCCACGCCCGGAGC
TGCTTCCTGACGGTGCAGCCGCAAGGCATCGCAGGGGCCCCGCGCTACTGCCCTGCTCCCTCAAAGTCCCAGGTCCCCTCCCCTGGTGCT
GATCATTAACCAGGAGGCCGTATAAGGAGCTAGCGGCCCTGGCGAGAGGGAAGGACGCAACGCTGCCACCATGGACAGTAGCACCTGGAG
CCCCAAGACCACCGCGGTCACCCGGCCTGTTGAGACCCACGAGCTCATTCGCAATGCAGCCGATATCTCCATCATCGTTATCTACTTCGT
GGTAGTGATGGCCGTCGGACTGTGGGCTATGTTTTCCACCAATCGTGGGACTGTTGGAGGCTTCTTCCTGGCAGGCCGAAGTATGGTGTG
GTGGCCGATTGGAGCCTCCCTCTTTGCTAGTAACATTGGAAGTGGCCACTTTGTGGGGCTGGCCGGGACTGGGGCAGCTTCAGGCATCGC
CATTGGAGGCTTTGAATGGAATGCCCTGGTTTTGGTGGTTGTGCTGGGCTGGCTGTTTGTCCCCATCTATATTAAGGCTGGGGTGGTGAC
AATGCCAGAGTACCTGAGGAAGCGGTTTGGAGGCCAGCGGATCCAGGTCTACCTTTCCCTTCTGTCCCTGCTGCTCTACATTTTCACCAA
GATCTCGGCAGACATCTTCTCGGGGGCCATATTCATCAATCTGGCCTTAGGCCTGAATCTGTATTTAGCCATCTTTCTCTTATTGGCAAT
CACTGCCCTTTACACAATTACAGGGGGCCTGGCGGCGGTGATTTACACGGACACCTTGCAGACGGTGATCATGCTGGTGGGGTCTTTAAT
CCTGACTGGGTTTGCTTTTCACGAAGTGGGAGGCTATGACGCCTTCATGGAAAAGTACATGAAAGCCATTCCAACCATAGTGTCTGATGG
CAACACCACCTTTCAGGAAAAATGCTACACTCCAAGGGCCGACTCCTTCCACATCTTCCGAGATCCCCTCACGGGAGACCTCCCATGGCC
TGGGTTCATCTTTGGGATGTCCATCCTTACCTTGTGGTACTGGTGCACAGATCAGGTCATTGTGCAGCGCTGCCTCTCAGCCAAGAATAT
GTCTCACGTGAAGGGTGGCTGCATCCTGTGTGGGTATCTAAAGCTGATGCCCATGTTCATCATGGTGATGCCAGGAATGATCAGCCGCAT
TCTGTACACAGAAAAAATTGCCTGTGTCGTCCCTTCAGAATGTGAGAAATATTGCGGTACCAAGGTTGGCTGTACCAACATCGCCTATCC
AACCTTAGTGGTGGAGCTCATGCCCAATGGACTGCGAGGCCTGATGCTATCAGTCATGCTGGCCTCCCTCATGAGCTCCCTGACCTCCAT
CTTCAACAGCGCCAGCACCCTCTTCACCATGGACATCTACGCCAAGGTCCGCAAGAGAGCATCTGAGAAAGAGCTCATGATTGCCGGAAG
GTTGTTTATCCTGGTGCTGATTGGCATCAGCATCGCCTGGGTGCCCATTGTGCAGTCAGCACAAAGTGGGCAACTCTTCGATTACATCCA
GTCCATCACCAGTTACTTGGGACCACCCATTGCGGCTGTCTTCCTGCTTGCTATTTTCTGGAAGAGAGTCAATGAGCCAGAGCAGAGTTT
CAGTTTTGGCAGCAGCGTCCAGTGCCCTGCCAGTAGCTCCTAGAGAGGCAGGGGTTACCAACTGGCCAGCAGGCTGTGTCCCTGAAGTCA
GATCAACGGGAGAGAAGGAAGTGGCTAAAACATTGCACAGGAGAAGTCGGCCTGAGTGGTGCGGCGCTCGGGACCCACCAGCAATGCTGC
TCTTCGTGCTCACCTGCCTGCTGGCGGTCTTCCCAGCCATCTCCACGAAGAGTCCCATATTTGGTCCCGAGGAGGTGAATAGTGTGGAAG
GTAACTCAGTGTCCATCACGTGCTACTACCCACCCACCTCTGTCAACCGGCACACCCGGAAGTACTGGTGCCGGCAGGGAGCTAGAGGTG
GCTGCATAACCCTCATCTCCTCGGAGGGCTACGTCTCCAGCAAATATGCAGGCAGGGCTAACCTCACCAACTTCCCGGAGAACGGCACAT
TTGTGGTGAACATTGCCCAGCTGAGCCAGGATGACTCCGGGCGCTACAAGTGTGGCCTGGGCATCAATAGCCGAGGCCTGTCCTTTGATG
TCAGCCTGGAGGTCAGCCAGGGTCCTGGGCTCCTAAATGACACTAAAGTCTACACAGTGGACCTGGGCAGAACGGTGACCATCAACTGCC
CTTTCAAGACTGAGAATGCTCAAAAGAGGAAGTCCTTGTACAAGCAGATAGGCCTGTACCCTGTGCTGGTCATCGACTCCAGTGGTTATG
TAAATCCCAACTATACAGGAAGAATACGCCTTGATATTCAGGGTACTGGCCAGTTACTGTTCAGCGTTGTCATCAACCAACTCAGGCTCA
GCGATGCTGGGCAGTATCTCTGCCAGGCTGGGGATGATTCCAATAGTAATAAGAAGAATGCTGACCTCCAAGTGCTAAAGCCCGAGCCCG
AGCTGGTTTATGAAGACCTGAGGGGCTCAGTGACCTTCCACTGTGCCCTGGGCCCTGAGGTGGCAAACGTGGCCAAATTTCTGTGCCGAC
AGAGCAGTGGGGAAAACTGTGACGTGGTCGTCAACACCCTGGGGAAGAGGGCCCCAGCCTTTGAGGGCAGGATCCTGCTCAACCCCCAGG
ACAAGGATGGCTCATTCAGTGTGGTGATCACAGGCCTGAGGAAGGAGGATGCAGGGCGCTACCTGTGTGGAGCCCATTCGGATGGTCAGC
TGCAGGAAGGCTCGCCTATCCAGGCCTGGCAACTCTTCGTCAATGAGGAGTCCACGATTCCCCGCAGCCCCACTGTGGTGAAGGGGGTGG
CAGGAGGCTCTGTGGCCGTGCTCTGCCCCTACAACCGTAAGGAAAGCAAAAGCATCAAGTACTGGTGTCTCTGGGAAGGGGCCCAGAATG
GCCGCTGCCCCCTGCTGGTGGACAGCGAGGGGTGGGTTAAGGCCCAGTACGAGGGCCGCCTCTCCCTGCTGGAGGAGCCAGGCAACGGCA
CCTTCACTGTCATCCTCAACCAGCTCACCAGCCGGGACGCCGGCTTCTACTGGTGTCTGACCAACGGCGATACTCTCTGGAGGACCACCG
TGGAGATCAAGATTATCGAAGGAGAACCAAACCTCAAGGTACCAGGGAATGTCACGGCTGTGCTGGGAGAGACTCTCAAGGTCCCCTGTC
ACTTTCCATGCAAATTCTCCTCGTACGAGAAATACTGGTGCAAGTGGAATAACACGGGCTGCCAGGCCCTGCCCAGCCAAGACGAAGGCC
CCAGCAAGGCCTTCGTGAACTGTGACGAGAACAGCCGGCTTGTCTCCCTGACCCTGAACCTGGTGACCAGGGCTGATGAGGGCTGGTACT
GGTGTGGAGTGAAGCAGGGCCACTTCTATGGAGAGACTGCAGCCGTCTATGTGGCAGTTGAAGAGAGGAAGGCAGCGGGGTCCCGCGATG
TCAGCCTAGCGAAGGCAGACGCTGCTCCTGATGAGAAGGTGCTAGACTCTGGTTTTCGGGAGATTGAGAACAAAGCCATTCAGGATCCCA
GGCTTTTTGCAGAGGAAAAGGCGGTGGCAGATACAAGAGATCAAGCCGATGGGAGCAGAGCATCTGTGGATTCCGGCAGCTCTGAGGAAC
AAGGTGGAAGCTCCAGAGCGCTGGTCTCCACCCTGGTGCCCCTGGGCCTGGTGCTGGCAGTGGGAGCCGTGGCTGTGGGGGTGGCCAGAG
CCCGGCACAGGAAGAACGTCGACCGAGTTTCAATCAGAAGCTACAGGACAGACATTAGCATGTCAGACTTCGAGAACTCCAGGGAATTTG
GAGCCAATGACAACATGGGAGCCTCTTCGATCACTCAGGAGACATCCCTCGGAGGAAAAGAAGAGTTTGTTGCCACCACTGAGAGCACCA
CAGAGACCAAAGAACCCAAGAAGGCAAAAAGGTCATCCAAGGAGGAAGCCGAGATGGCCTACAAAGACTTCCTGCTCCAGTCCAGCACCG
TGGCCGCCGAGGCCCAGGACGGCCCCCAGGAAGCCTAGACGGTGTCGCCGCCTGCTCCCTGCACCCATGACAATCACCTTCAGAATCATG
TCGATCCTGGGGCCCTCAGCTCCTGGGGACCCCACTCCCTGCTCTAACACCTGCCTAGGTTTTTCCTACTGTCCTCAGAGGCGTGCTGGT
CCCCTCCTCAGTGACATCAAAGCCTGGCCTAATTGTTCCTATTGGGGATGAGGGTGGCATGAGGAGGTCCCACTTGCAACTTCTTTCTGT
TGAGAGAACCTCAGGTACGGAGAAGAATAGAGGTCCTCATGGGTCCCTTGAAGGAAGAGGGACCAGGGTGGGAGAGCTGATTGCAGAAAG
GAGAGACGTGCAGCGCCCCTCTGCACCCTTATCATGGGATGTCAACAGAATTTTTCCCTCCACTCCATCCCTCCCTCCCGTCCTTCCCCT
CTTCTTCTTTCCTTCCATCAAAAGATGTATTTGAATTCATACTAGAATTCAGGTGCTTTGCTAGATGCTGTGACAGGTATGCCACCAACA
CTGCTCACAGCCTTTCTGAGGACACCAGTGAAAGAAGCCACAGCTCTTCTTGGCGTATTTATACTCACTGAGTCTTAACTTTTCACCAGG
GGTGCTCACCTCTGCCCCTATTGGGAGAGGTCATAAAATGTCTCGAGTCCTAAGGCCTTAGGGGTCATGTATGATGAGCATACACACAGG
TAATTATAAACCCACATTCTTACCATTTCACACATAAGAAAATTGAGGTTTGGAAGAGTGAAGCGTTTTTCTTTTTCTTTTTTTTTTTTG
AGACGGAGTCTCTCACTGTCGCCCAGGCTGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTGACACCATTCT
CCTGCCTCACCCTCCCAAGTAGCTGGGACTACAGGCGCCTGCCAGCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCA
CCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCTGCCTCTGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACC
GCGTCCGGCCTCTTTTTTTCTTTTCTTTTTTTTGAGACAAAGTCTCACTGTGTCACCCAGACTGGAATGCAGTGACACAATCTCGGCTCA
CTGAAACCTCTGCCTTCCAGGTTCAAGCTATTCTCATGCCTCAGCCTCTCAAGTAGCTGGGACTACAGATGTGGGCCACCATGTCTGGCT
AATTTTTTTTTTTTTTTTTTTTTTTTGTAGAGACAGGGTTTCGCCATGTTGACGAGACTGGTCTCGAACTCCTGGCCTCAAGTGATCTGC
CGCCTCAGCTTCTCAAAGTACTGGGATTATATAGGCATGAGCCACTGAGCCTGGCCCTGAAGCGTTTTTCTCAAAGGCCCTCAGTGAGAT
AAATTAGATTTGGCATCTCCTGTCCTGGGCCAGGGATCTCTCTACAAGAGCCCCTGCCCCTCTGTTGGAGGCACAGTTTTAGAATAAGGA
GGAGGAGGGAGAAGAGAAAATGTAAAGGAGGGAGATCTTTCCCAGGCCGCACCATTTCTGTCACTCACATGGACCCAAGATAAAAGAATG
GCCAAACCCTCACAACCCCTGATGTTTGAAGAGTTCCAAGTTGAAGGGAAACAAAGAAGTGTTTGATGGTGCCAGAGAGGGGCTGCTCTC
CAGAAAGCTAAAATTTAATTTCTTTTTTCCTCTGAGTTCTGTACTTCAACCAGCCTACAAGCTGGCACTTGCTAACAAATCAGAAATATG

>83414_83414_1_SLC5A1-PIGR_SLC5A1_chr22_32495338_ENST00000266088_PIGR_chr1_207119811_ENST00000356495_length(amino acids)=875AA_BP=50
MASASPGCPLCSQHKVGNSSITSSPSPVTWDHPLRLSSCLLFSGRESMSQSRVSVLAAASSALPVAPREAGVTNWPAGCVPEVRSTGEKE
VAKTLHRRSRPEWCGARDPPAMLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLIS
SEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENA
QKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDL
RGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPI
QAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILN
QLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFVN
CDENSRLVSLTLNLVTRADEGWYWCGVKQGHFYGETAAVYVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQDPRLFAEEK
AVADTRDQADGSRASVDSGSSEEQGGSSRALVSTLVPLGLVLAVGAVAVGVARARHRKNVDRVSIRSYRTDISMSDFENSREFGANDNMG

--------------------------------------------------------------
>83414_83414_2_SLC5A1-PIGR_SLC5A1_chr22_32495338_ENST00000543737_PIGR_chr1_207119811_ENST00000356495_length(transcript)=5675nt_BP=1396nt
ACTGCACTCCTGCCTGGGCGACAGAAAAAGACTCTGTCCCAAAAGTGGGCTCTTTGAAGGCTAGAAGGTATTTGGGGCAGCAGACTTGTG
TGGAAGCAGTTATCAAAGTGGGGATGTGACACGCACCAGGAGAGGGGAACAGACAACACATGAGATTGGAGCCTCCCTCTTTGCTAGTAA
CATTGGAAGTGGCCACTTTGTGGGGCTGGCCGGGACTGGGGCAGCTTCAGGCATCGCCATTGGAGGCTTTGAATGGAATGCCCTGGTTTT
GGTGGTTGTGCTGGGCTGGCTGTTTGTCCCCATCTATATTAAGGCTGGGGTGGTGACAATGCCAGAGTACCTGAGGAAGCGGTTTGGAGG
CCAGCGGATCCAGGTCTACCTTTCCCTTCTGTCCCTGCTGCTCTACATTTTCACCAAGATCTCGGCAGACATCTTCTCGGGGGCCATATT
CATCAATCTGGCCTTAGGCCTGAATCTGTATTTAGCCATCTTTCTCTTATTGGCAATCACTGCCCTTTACACAATTACAGGGGGCCTGGC
GGCGGTGATTTACACGGACACCTTGCAGACGGTGATCATGCTGGTGGGGTCTTTAATCCTGACTGGGTTTGCTTTTCACGAAGTGGGAGG
CTATGACGCCTTCATGGAAAAGTACATGAAAGCCATTCCAACCATAGTGTCTGATGGCAACACCACCTTTCAGGAAAAATGCTACACTCC
AAGGGCCGACTCCTTCCACATCTTCCGAGATCCCCTCACGGGAGACCTCCCATGGCCTGGGTTCATCTTTGGGATGTCCATCCTTACCTT
GTGGTACTGGTGCACAGATCAGGTCATTGTGCAGCGCTGCCTCTCAGCCAAGAATATGTCTCACGTGAAGGGTGGCTGCATCCTGTGTGG
GTATCTAAAGCTGATGCCCATGTTCATCATGGTGATGCCAGGAATGATCAGCCGCATTCTGTACACAGAAAAAATTGCCTGTGTCGTCCC
TTCAGAATGTGAGAAATATTGCGGTACCAAGGTTGGCTGTACCAACATCGCCTATCCAACCTTAGTGGTGGAGCTCATGCCCAATGGACT
GCGAGGCCTGATGCTATCAGTCATGCTGGCCTCCCTCATGAGCTCCCTGACCTCCATCTTCAACAGCGCCAGCACCCTCTTCACCATGGA
CATCTACGCCAAGGTCCGCAAGAGAGCATCTGAGAAAGAGCTCATGATTGCCGGAAGGTTGTTTATCCTGGTGCTGATTGGCATCAGCAT
CGCCTGGGTGCCCATTGTGCAGTCAGCACAAAGTGGGCAACTCTTCGATTACATCCAGTCCATCACCAGTTACTTGGGACCACCCATTGC
GGCTGTCTTCCTGCTTGCTATTTTCTGGAAGAGAGTCAATGAGCCAGAGCAGAGTTTCAGTTTTGGCAGCAGCGTCCAGTGCCCTGCCAG
TAGCTCCTAGAGAGGCAGGGGTTACCAACTGGCCAGCAGGCTGTGTCCCTGAAGTCAGATCAACGGGAGAGAAGGAAGTGGCTAAAACAT
TGCACAGGAGAAGTCGGCCTGAGTGGTGCGGCGCTCGGGACCCACCAGCAATGCTGCTCTTCGTGCTCACCTGCCTGCTGGCGGTCTTCC
CAGCCATCTCCACGAAGAGTCCCATATTTGGTCCCGAGGAGGTGAATAGTGTGGAAGGTAACTCAGTGTCCATCACGTGCTACTACCCAC
CCACCTCTGTCAACCGGCACACCCGGAAGTACTGGTGCCGGCAGGGAGCTAGAGGTGGCTGCATAACCCTCATCTCCTCGGAGGGCTACG
TCTCCAGCAAATATGCAGGCAGGGCTAACCTCACCAACTTCCCGGAGAACGGCACATTTGTGGTGAACATTGCCCAGCTGAGCCAGGATG
ACTCCGGGCGCTACAAGTGTGGCCTGGGCATCAATAGCCGAGGCCTGTCCTTTGATGTCAGCCTGGAGGTCAGCCAGGGTCCTGGGCTCC
TAAATGACACTAAAGTCTACACAGTGGACCTGGGCAGAACGGTGACCATCAACTGCCCTTTCAAGACTGAGAATGCTCAAAAGAGGAAGT
CCTTGTACAAGCAGATAGGCCTGTACCCTGTGCTGGTCATCGACTCCAGTGGTTATGTAAATCCCAACTATACAGGAAGAATACGCCTTG
ATATTCAGGGTACTGGCCAGTTACTGTTCAGCGTTGTCATCAACCAACTCAGGCTCAGCGATGCTGGGCAGTATCTCTGCCAGGCTGGGG
ATGATTCCAATAGTAATAAGAAGAATGCTGACCTCCAAGTGCTAAAGCCCGAGCCCGAGCTGGTTTATGAAGACCTGAGGGGCTCAGTGA
CCTTCCACTGTGCCCTGGGCCCTGAGGTGGCAAACGTGGCCAAATTTCTGTGCCGACAGAGCAGTGGGGAAAACTGTGACGTGGTCGTCA
ACACCCTGGGGAAGAGGGCCCCAGCCTTTGAGGGCAGGATCCTGCTCAACCCCCAGGACAAGGATGGCTCATTCAGTGTGGTGATCACAG
GCCTGAGGAAGGAGGATGCAGGGCGCTACCTGTGTGGAGCCCATTCGGATGGTCAGCTGCAGGAAGGCTCGCCTATCCAGGCCTGGCAAC
TCTTCGTCAATGAGGAGTCCACGATTCCCCGCAGCCCCACTGTGGTGAAGGGGGTGGCAGGAGGCTCTGTGGCCGTGCTCTGCCCCTACA
ACCGTAAGGAAAGCAAAAGCATCAAGTACTGGTGTCTCTGGGAAGGGGCCCAGAATGGCCGCTGCCCCCTGCTGGTGGACAGCGAGGGGT
GGGTTAAGGCCCAGTACGAGGGCCGCCTCTCCCTGCTGGAGGAGCCAGGCAACGGCACCTTCACTGTCATCCTCAACCAGCTCACCAGCC
GGGACGCCGGCTTCTACTGGTGTCTGACCAACGGCGATACTCTCTGGAGGACCACCGTGGAGATCAAGATTATCGAAGGAGAACCAAACC
TCAAGGTACCAGGGAATGTCACGGCTGTGCTGGGAGAGACTCTCAAGGTCCCCTGTCACTTTCCATGCAAATTCTCCTCGTACGAGAAAT
ACTGGTGCAAGTGGAATAACACGGGCTGCCAGGCCCTGCCCAGCCAAGACGAAGGCCCCAGCAAGGCCTTCGTGAACTGTGACGAGAACA
GCCGGCTTGTCTCCCTGACCCTGAACCTGGTGACCAGGGCTGATGAGGGCTGGTACTGGTGTGGAGTGAAGCAGGGCCACTTCTATGGAG
AGACTGCAGCCGTCTATGTGGCAGTTGAAGAGAGGAAGGCAGCGGGGTCCCGCGATGTCAGCCTAGCGAAGGCAGACGCTGCTCCTGATG
AGAAGGTGCTAGACTCTGGTTTTCGGGAGATTGAGAACAAAGCCATTCAGGATCCCAGGCTTTTTGCAGAGGAAAAGGCGGTGGCAGATA
CAAGAGATCAAGCCGATGGGAGCAGAGCATCTGTGGATTCCGGCAGCTCTGAGGAACAAGGTGGAAGCTCCAGAGCGCTGGTCTCCACCC
TGGTGCCCCTGGGCCTGGTGCTGGCAGTGGGAGCCGTGGCTGTGGGGGTGGCCAGAGCCCGGCACAGGAAGAACGTCGACCGAGTTTCAA
TCAGAAGCTACAGGACAGACATTAGCATGTCAGACTTCGAGAACTCCAGGGAATTTGGAGCCAATGACAACATGGGAGCCTCTTCGATCA
CTCAGGAGACATCCCTCGGAGGAAAAGAAGAGTTTGTTGCCACCACTGAGAGCACCACAGAGACCAAAGAACCCAAGAAGGCAAAAAGGT
CATCCAAGGAGGAAGCCGAGATGGCCTACAAAGACTTCCTGCTCCAGTCCAGCACCGTGGCCGCCGAGGCCCAGGACGGCCCCCAGGAAG
CCTAGACGGTGTCGCCGCCTGCTCCCTGCACCCATGACAATCACCTTCAGAATCATGTCGATCCTGGGGCCCTCAGCTCCTGGGGACCCC
ACTCCCTGCTCTAACACCTGCCTAGGTTTTTCCTACTGTCCTCAGAGGCGTGCTGGTCCCCTCCTCAGTGACATCAAAGCCTGGCCTAAT
TGTTCCTATTGGGGATGAGGGTGGCATGAGGAGGTCCCACTTGCAACTTCTTTCTGTTGAGAGAACCTCAGGTACGGAGAAGAATAGAGG
TCCTCATGGGTCCCTTGAAGGAAGAGGGACCAGGGTGGGAGAGCTGATTGCAGAAAGGAGAGACGTGCAGCGCCCCTCTGCACCCTTATC
ATGGGATGTCAACAGAATTTTTCCCTCCACTCCATCCCTCCCTCCCGTCCTTCCCCTCTTCTTCTTTCCTTCCATCAAAAGATGTATTTG
AATTCATACTAGAATTCAGGTGCTTTGCTAGATGCTGTGACAGGTATGCCACCAACACTGCTCACAGCCTTTCTGAGGACACCAGTGAAA
GAAGCCACAGCTCTTCTTGGCGTATTTATACTCACTGAGTCTTAACTTTTCACCAGGGGTGCTCACCTCTGCCCCTATTGGGAGAGGTCA
TAAAATGTCTCGAGTCCTAAGGCCTTAGGGGTCATGTATGATGAGCATACACACAGGTAATTATAAACCCACATTCTTACCATTTCACAC
ATAAGAAAATTGAGGTTTGGAAGAGTGAAGCGTTTTTCTTTTTCTTTTTTTTTTTTGAGACGGAGTCTCTCACTGTCGCCCAGGCTGGAG
TGCAGTGGCGCAATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTGACACCATTCTCCTGCCTCACCCTCCCAAGTAGCTGGGACTACA
GGCGCCTGCCAGCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGAC
CTCGTGATCCGCCTGCCTCTGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGTCCGGCCTCTTTTTTTCTTTTCTTTTTTTT
GAGACAAAGTCTCACTGTGTCACCCAGACTGGAATGCAGTGACACAATCTCGGCTCACTGAAACCTCTGCCTTCCAGGTTCAAGCTATTC
TCATGCCTCAGCCTCTCAAGTAGCTGGGACTACAGATGTGGGCCACCATGTCTGGCTAATTTTTTTTTTTTTTTTTTTTTTTTGTAGAGA
CAGGGTTTCGCCATGTTGACGAGACTGGTCTCGAACTCCTGGCCTCAAGTGATCTGCCGCCTCAGCTTCTCAAAGTACTGGGATTATATA
GGCATGAGCCACTGAGCCTGGCCCTGAAGCGTTTTTCTCAAAGGCCCTCAGTGAGATAAATTAGATTTGGCATCTCCTGTCCTGGGCCAG
GGATCTCTCTACAAGAGCCCCTGCCCCTCTGTTGGAGGCACAGTTTTAGAATAAGGAGGAGGAGGGAGAAGAGAAAATGTAAAGGAGGGA
GATCTTTCCCAGGCCGCACCATTTCTGTCACTCACATGGACCCAAGATAAAAGAATGGCCAAACCCTCACAACCCCTGATGTTTGAAGAG
TTCCAAGTTGAAGGGAAACAAAGAAGTGTTTGATGGTGCCAGAGAGGGGCTGCTCTCCAGAAAGCTAAAATTTAATTTCTTTTTTCCTCT
GAGTTCTGTACTTCAACCAGCCTACAAGCTGGCACTTGCTAACAAATCAGAAATATGACAATTAATGATTAAAGACTGTGATTGCCACCA

>83414_83414_2_SLC5A1-PIGR_SLC5A1_chr22_32495338_ENST00000543737_PIGR_chr1_207119811_ENST00000356495_length(amino acids)=875AA_BP=50
MASASPGCPLCSQHKVGNSSITSSPSPVTWDHPLRLSSCLLFSGRESMSQSRVSVLAAASSALPVAPREAGVTNWPAGCVPEVRSTGEKE
VAKTLHRRSRPEWCGARDPPAMLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLIS
SEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENA
QKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDL
RGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPI
QAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILN
QLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFVN
CDENSRLVSLTLNLVTRADEGWYWCGVKQGHFYGETAAVYVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQDPRLFAEEK
AVADTRDQADGSRASVDSGSSEEQGGSSRALVSTLVPLGLVLAVGAVAVGVARARHRKNVDRVSIRSYRTDISMSDFENSREFGANDNMG

--------------------------------------------------------------
>83414_83414_3_SLC5A1-PIGR_SLC5A1_chr22_32495342_ENST00000266088_PIGR_chr1_207119808_ENST00000356495_length(transcript)=5978nt_BP=1699nt
CCCCATTCGCAGGACAGCTCTTACCTGCCGGGCCGCCGCCCCAGCCAACAGCTCAGCCGGGTGCTCCTTCCTGGGCTCCACGCCCGGAGC
TGCTTCCTGACGGTGCAGCCGCAAGGCATCGCAGGGGCCCCGCGCTACTGCCCTGCTCCCTCAAAGTCCCAGGTCCCCTCCCCTGGTGCT
GATCATTAACCAGGAGGCCGTATAAGGAGCTAGCGGCCCTGGCGAGAGGGAAGGACGCAACGCTGCCACCATGGACAGTAGCACCTGGAG
CCCCAAGACCACCGCGGTCACCCGGCCTGTTGAGACCCACGAGCTCATTCGCAATGCAGCCGATATCTCCATCATCGTTATCTACTTCGT
GGTAGTGATGGCCGTCGGACTGTGGGCTATGTTTTCCACCAATCGTGGGACTGTTGGAGGCTTCTTCCTGGCAGGCCGAAGTATGGTGTG
GTGGCCGATTGGAGCCTCCCTCTTTGCTAGTAACATTGGAAGTGGCCACTTTGTGGGGCTGGCCGGGACTGGGGCAGCTTCAGGCATCGC
CATTGGAGGCTTTGAATGGAATGCCCTGGTTTTGGTGGTTGTGCTGGGCTGGCTGTTTGTCCCCATCTATATTAAGGCTGGGGTGGTGAC
AATGCCAGAGTACCTGAGGAAGCGGTTTGGAGGCCAGCGGATCCAGGTCTACCTTTCCCTTCTGTCCCTGCTGCTCTACATTTTCACCAA
GATCTCGGCAGACATCTTCTCGGGGGCCATATTCATCAATCTGGCCTTAGGCCTGAATCTGTATTTAGCCATCTTTCTCTTATTGGCAAT
CACTGCCCTTTACACAATTACAGGGGGCCTGGCGGCGGTGATTTACACGGACACCTTGCAGACGGTGATCATGCTGGTGGGGTCTTTAAT
CCTGACTGGGTTTGCTTTTCACGAAGTGGGAGGCTATGACGCCTTCATGGAAAAGTACATGAAAGCCATTCCAACCATAGTGTCTGATGG
CAACACCACCTTTCAGGAAAAATGCTACACTCCAAGGGCCGACTCCTTCCACATCTTCCGAGATCCCCTCACGGGAGACCTCCCATGGCC
TGGGTTCATCTTTGGGATGTCCATCCTTACCTTGTGGTACTGGTGCACAGATCAGGTCATTGTGCAGCGCTGCCTCTCAGCCAAGAATAT
GTCTCACGTGAAGGGTGGCTGCATCCTGTGTGGGTATCTAAAGCTGATGCCCATGTTCATCATGGTGATGCCAGGAATGATCAGCCGCAT
TCTGTACACAGAAAAAATTGCCTGTGTCGTCCCTTCAGAATGTGAGAAATATTGCGGTACCAAGGTTGGCTGTACCAACATCGCCTATCC
AACCTTAGTGGTGGAGCTCATGCCCAATGGACTGCGAGGCCTGATGCTATCAGTCATGCTGGCCTCCCTCATGAGCTCCCTGACCTCCAT
CTTCAACAGCGCCAGCACCCTCTTCACCATGGACATCTACGCCAAGGTCCGCAAGAGAGCATCTGAGAAAGAGCTCATGATTGCCGGAAG
GTTGTTTATCCTGGTGCTGATTGGCATCAGCATCGCCTGGGTGCCCATTGTGCAGTCAGCACAAAGTGGGCAACTCTTCGATTACATCCA
GTCCATCACCAGTTACTTGGGACCACCCATTGCGGCTGTCTTCCTGCTTGCTATTTTCTGGAAGAGAGTCAATGAGCCAGAGCAGAGTTT
CAGTTTTGGCAGCAGCGTCCAGTGCCCTGCCAGTAGCTCCTAGAGAGGCAGGGGTTACCAACTGGCCAGCAGGCTGTGTCCCTGAAGTCA
GATCAACGGGAGAGAAGGAAGTGGCTAAAACATTGCACAGGAGAAGTCGGCCTGAGTGGTGCGGCGCTCGGGACCCACCAGCAATGCTGC
TCTTCGTGCTCACCTGCCTGCTGGCGGTCTTCCCAGCCATCTCCACGAAGAGTCCCATATTTGGTCCCGAGGAGGTGAATAGTGTGGAAG
GTAACTCAGTGTCCATCACGTGCTACTACCCACCCACCTCTGTCAACCGGCACACCCGGAAGTACTGGTGCCGGCAGGGAGCTAGAGGTG
GCTGCATAACCCTCATCTCCTCGGAGGGCTACGTCTCCAGCAAATATGCAGGCAGGGCTAACCTCACCAACTTCCCGGAGAACGGCACAT
TTGTGGTGAACATTGCCCAGCTGAGCCAGGATGACTCCGGGCGCTACAAGTGTGGCCTGGGCATCAATAGCCGAGGCCTGTCCTTTGATG
TCAGCCTGGAGGTCAGCCAGGGTCCTGGGCTCCTAAATGACACTAAAGTCTACACAGTGGACCTGGGCAGAACGGTGACCATCAACTGCC
CTTTCAAGACTGAGAATGCTCAAAAGAGGAAGTCCTTGTACAAGCAGATAGGCCTGTACCCTGTGCTGGTCATCGACTCCAGTGGTTATG
TAAATCCCAACTATACAGGAAGAATACGCCTTGATATTCAGGGTACTGGCCAGTTACTGTTCAGCGTTGTCATCAACCAACTCAGGCTCA
GCGATGCTGGGCAGTATCTCTGCCAGGCTGGGGATGATTCCAATAGTAATAAGAAGAATGCTGACCTCCAAGTGCTAAAGCCCGAGCCCG
AGCTGGTTTATGAAGACCTGAGGGGCTCAGTGACCTTCCACTGTGCCCTGGGCCCTGAGGTGGCAAACGTGGCCAAATTTCTGTGCCGAC
AGAGCAGTGGGGAAAACTGTGACGTGGTCGTCAACACCCTGGGGAAGAGGGCCCCAGCCTTTGAGGGCAGGATCCTGCTCAACCCCCAGG
ACAAGGATGGCTCATTCAGTGTGGTGATCACAGGCCTGAGGAAGGAGGATGCAGGGCGCTACCTGTGTGGAGCCCATTCGGATGGTCAGC
TGCAGGAAGGCTCGCCTATCCAGGCCTGGCAACTCTTCGTCAATGAGGAGTCCACGATTCCCCGCAGCCCCACTGTGGTGAAGGGGGTGG
CAGGAGGCTCTGTGGCCGTGCTCTGCCCCTACAACCGTAAGGAAAGCAAAAGCATCAAGTACTGGTGTCTCTGGGAAGGGGCCCAGAATG
GCCGCTGCCCCCTGCTGGTGGACAGCGAGGGGTGGGTTAAGGCCCAGTACGAGGGCCGCCTCTCCCTGCTGGAGGAGCCAGGCAACGGCA
CCTTCACTGTCATCCTCAACCAGCTCACCAGCCGGGACGCCGGCTTCTACTGGTGTCTGACCAACGGCGATACTCTCTGGAGGACCACCG
TGGAGATCAAGATTATCGAAGGAGAACCAAACCTCAAGGTACCAGGGAATGTCACGGCTGTGCTGGGAGAGACTCTCAAGGTCCCCTGTC
ACTTTCCATGCAAATTCTCCTCGTACGAGAAATACTGGTGCAAGTGGAATAACACGGGCTGCCAGGCCCTGCCCAGCCAAGACGAAGGCC
CCAGCAAGGCCTTCGTGAACTGTGACGAGAACAGCCGGCTTGTCTCCCTGACCCTGAACCTGGTGACCAGGGCTGATGAGGGCTGGTACT
GGTGTGGAGTGAAGCAGGGCCACTTCTATGGAGAGACTGCAGCCGTCTATGTGGCAGTTGAAGAGAGGAAGGCAGCGGGGTCCCGCGATG
TCAGCCTAGCGAAGGCAGACGCTGCTCCTGATGAGAAGGTGCTAGACTCTGGTTTTCGGGAGATTGAGAACAAAGCCATTCAGGATCCCA
GGCTTTTTGCAGAGGAAAAGGCGGTGGCAGATACAAGAGATCAAGCCGATGGGAGCAGAGCATCTGTGGATTCCGGCAGCTCTGAGGAAC
AAGGTGGAAGCTCCAGAGCGCTGGTCTCCACCCTGGTGCCCCTGGGCCTGGTGCTGGCAGTGGGAGCCGTGGCTGTGGGGGTGGCCAGAG
CCCGGCACAGGAAGAACGTCGACCGAGTTTCAATCAGAAGCTACAGGACAGACATTAGCATGTCAGACTTCGAGAACTCCAGGGAATTTG
GAGCCAATGACAACATGGGAGCCTCTTCGATCACTCAGGAGACATCCCTCGGAGGAAAAGAAGAGTTTGTTGCCACCACTGAGAGCACCA
CAGAGACCAAAGAACCCAAGAAGGCAAAAAGGTCATCCAAGGAGGAAGCCGAGATGGCCTACAAAGACTTCCTGCTCCAGTCCAGCACCG
TGGCCGCCGAGGCCCAGGACGGCCCCCAGGAAGCCTAGACGGTGTCGCCGCCTGCTCCCTGCACCCATGACAATCACCTTCAGAATCATG
TCGATCCTGGGGCCCTCAGCTCCTGGGGACCCCACTCCCTGCTCTAACACCTGCCTAGGTTTTTCCTACTGTCCTCAGAGGCGTGCTGGT
CCCCTCCTCAGTGACATCAAAGCCTGGCCTAATTGTTCCTATTGGGGATGAGGGTGGCATGAGGAGGTCCCACTTGCAACTTCTTTCTGT
TGAGAGAACCTCAGGTACGGAGAAGAATAGAGGTCCTCATGGGTCCCTTGAAGGAAGAGGGACCAGGGTGGGAGAGCTGATTGCAGAAAG
GAGAGACGTGCAGCGCCCCTCTGCACCCTTATCATGGGATGTCAACAGAATTTTTCCCTCCACTCCATCCCTCCCTCCCGTCCTTCCCCT
CTTCTTCTTTCCTTCCATCAAAAGATGTATTTGAATTCATACTAGAATTCAGGTGCTTTGCTAGATGCTGTGACAGGTATGCCACCAACA
CTGCTCACAGCCTTTCTGAGGACACCAGTGAAAGAAGCCACAGCTCTTCTTGGCGTATTTATACTCACTGAGTCTTAACTTTTCACCAGG
GGTGCTCACCTCTGCCCCTATTGGGAGAGGTCATAAAATGTCTCGAGTCCTAAGGCCTTAGGGGTCATGTATGATGAGCATACACACAGG
TAATTATAAACCCACATTCTTACCATTTCACACATAAGAAAATTGAGGTTTGGAAGAGTGAAGCGTTTTTCTTTTTCTTTTTTTTTTTTG
AGACGGAGTCTCTCACTGTCGCCCAGGCTGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTGACACCATTCT
CCTGCCTCACCCTCCCAAGTAGCTGGGACTACAGGCGCCTGCCAGCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCA
CCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCTGCCTCTGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACC
GCGTCCGGCCTCTTTTTTTCTTTTCTTTTTTTTGAGACAAAGTCTCACTGTGTCACCCAGACTGGAATGCAGTGACACAATCTCGGCTCA
CTGAAACCTCTGCCTTCCAGGTTCAAGCTATTCTCATGCCTCAGCCTCTCAAGTAGCTGGGACTACAGATGTGGGCCACCATGTCTGGCT
AATTTTTTTTTTTTTTTTTTTTTTTTGTAGAGACAGGGTTTCGCCATGTTGACGAGACTGGTCTCGAACTCCTGGCCTCAAGTGATCTGC
CGCCTCAGCTTCTCAAAGTACTGGGATTATATAGGCATGAGCCACTGAGCCTGGCCCTGAAGCGTTTTTCTCAAAGGCCCTCAGTGAGAT
AAATTAGATTTGGCATCTCCTGTCCTGGGCCAGGGATCTCTCTACAAGAGCCCCTGCCCCTCTGTTGGAGGCACAGTTTTAGAATAAGGA
GGAGGAGGGAGAAGAGAAAATGTAAAGGAGGGAGATCTTTCCCAGGCCGCACCATTTCTGTCACTCACATGGACCCAAGATAAAAGAATG
GCCAAACCCTCACAACCCCTGATGTTTGAAGAGTTCCAAGTTGAAGGGAAACAAAGAAGTGTTTGATGGTGCCAGAGAGGGGCTGCTCTC
CAGAAAGCTAAAATTTAATTTCTTTTTTCCTCTGAGTTCTGTACTTCAACCAGCCTACAAGCTGGCACTTGCTAACAAATCAGAAATATG

>83414_83414_3_SLC5A1-PIGR_SLC5A1_chr22_32495342_ENST00000266088_PIGR_chr1_207119808_ENST00000356495_length(amino acids)=875AA_BP=50
MASASPGCPLCSQHKVGNSSITSSPSPVTWDHPLRLSSCLLFSGRESMSQSRVSVLAAASSALPVAPREAGVTNWPAGCVPEVRSTGEKE
VAKTLHRRSRPEWCGARDPPAMLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLIS
SEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENA
QKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDL
RGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPI
QAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILN
QLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFVN
CDENSRLVSLTLNLVTRADEGWYWCGVKQGHFYGETAAVYVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQDPRLFAEEK
AVADTRDQADGSRASVDSGSSEEQGGSSRALVSTLVPLGLVLAVGAVAVGVARARHRKNVDRVSIRSYRTDISMSDFENSREFGANDNMG

--------------------------------------------------------------
>83414_83414_4_SLC5A1-PIGR_SLC5A1_chr22_32495342_ENST00000543737_PIGR_chr1_207119808_ENST00000356495_length(transcript)=5675nt_BP=1396nt
ACTGCACTCCTGCCTGGGCGACAGAAAAAGACTCTGTCCCAAAAGTGGGCTCTTTGAAGGCTAGAAGGTATTTGGGGCAGCAGACTTGTG
TGGAAGCAGTTATCAAAGTGGGGATGTGACACGCACCAGGAGAGGGGAACAGACAACACATGAGATTGGAGCCTCCCTCTTTGCTAGTAA
CATTGGAAGTGGCCACTTTGTGGGGCTGGCCGGGACTGGGGCAGCTTCAGGCATCGCCATTGGAGGCTTTGAATGGAATGCCCTGGTTTT
GGTGGTTGTGCTGGGCTGGCTGTTTGTCCCCATCTATATTAAGGCTGGGGTGGTGACAATGCCAGAGTACCTGAGGAAGCGGTTTGGAGG
CCAGCGGATCCAGGTCTACCTTTCCCTTCTGTCCCTGCTGCTCTACATTTTCACCAAGATCTCGGCAGACATCTTCTCGGGGGCCATATT
CATCAATCTGGCCTTAGGCCTGAATCTGTATTTAGCCATCTTTCTCTTATTGGCAATCACTGCCCTTTACACAATTACAGGGGGCCTGGC
GGCGGTGATTTACACGGACACCTTGCAGACGGTGATCATGCTGGTGGGGTCTTTAATCCTGACTGGGTTTGCTTTTCACGAAGTGGGAGG
CTATGACGCCTTCATGGAAAAGTACATGAAAGCCATTCCAACCATAGTGTCTGATGGCAACACCACCTTTCAGGAAAAATGCTACACTCC
AAGGGCCGACTCCTTCCACATCTTCCGAGATCCCCTCACGGGAGACCTCCCATGGCCTGGGTTCATCTTTGGGATGTCCATCCTTACCTT
GTGGTACTGGTGCACAGATCAGGTCATTGTGCAGCGCTGCCTCTCAGCCAAGAATATGTCTCACGTGAAGGGTGGCTGCATCCTGTGTGG
GTATCTAAAGCTGATGCCCATGTTCATCATGGTGATGCCAGGAATGATCAGCCGCATTCTGTACACAGAAAAAATTGCCTGTGTCGTCCC
TTCAGAATGTGAGAAATATTGCGGTACCAAGGTTGGCTGTACCAACATCGCCTATCCAACCTTAGTGGTGGAGCTCATGCCCAATGGACT
GCGAGGCCTGATGCTATCAGTCATGCTGGCCTCCCTCATGAGCTCCCTGACCTCCATCTTCAACAGCGCCAGCACCCTCTTCACCATGGA
CATCTACGCCAAGGTCCGCAAGAGAGCATCTGAGAAAGAGCTCATGATTGCCGGAAGGTTGTTTATCCTGGTGCTGATTGGCATCAGCAT
CGCCTGGGTGCCCATTGTGCAGTCAGCACAAAGTGGGCAACTCTTCGATTACATCCAGTCCATCACCAGTTACTTGGGACCACCCATTGC
GGCTGTCTTCCTGCTTGCTATTTTCTGGAAGAGAGTCAATGAGCCAGAGCAGAGTTTCAGTTTTGGCAGCAGCGTCCAGTGCCCTGCCAG
TAGCTCCTAGAGAGGCAGGGGTTACCAACTGGCCAGCAGGCTGTGTCCCTGAAGTCAGATCAACGGGAGAGAAGGAAGTGGCTAAAACAT
TGCACAGGAGAAGTCGGCCTGAGTGGTGCGGCGCTCGGGACCCACCAGCAATGCTGCTCTTCGTGCTCACCTGCCTGCTGGCGGTCTTCC
CAGCCATCTCCACGAAGAGTCCCATATTTGGTCCCGAGGAGGTGAATAGTGTGGAAGGTAACTCAGTGTCCATCACGTGCTACTACCCAC
CCACCTCTGTCAACCGGCACACCCGGAAGTACTGGTGCCGGCAGGGAGCTAGAGGTGGCTGCATAACCCTCATCTCCTCGGAGGGCTACG
TCTCCAGCAAATATGCAGGCAGGGCTAACCTCACCAACTTCCCGGAGAACGGCACATTTGTGGTGAACATTGCCCAGCTGAGCCAGGATG
ACTCCGGGCGCTACAAGTGTGGCCTGGGCATCAATAGCCGAGGCCTGTCCTTTGATGTCAGCCTGGAGGTCAGCCAGGGTCCTGGGCTCC
TAAATGACACTAAAGTCTACACAGTGGACCTGGGCAGAACGGTGACCATCAACTGCCCTTTCAAGACTGAGAATGCTCAAAAGAGGAAGT
CCTTGTACAAGCAGATAGGCCTGTACCCTGTGCTGGTCATCGACTCCAGTGGTTATGTAAATCCCAACTATACAGGAAGAATACGCCTTG
ATATTCAGGGTACTGGCCAGTTACTGTTCAGCGTTGTCATCAACCAACTCAGGCTCAGCGATGCTGGGCAGTATCTCTGCCAGGCTGGGG
ATGATTCCAATAGTAATAAGAAGAATGCTGACCTCCAAGTGCTAAAGCCCGAGCCCGAGCTGGTTTATGAAGACCTGAGGGGCTCAGTGA
CCTTCCACTGTGCCCTGGGCCCTGAGGTGGCAAACGTGGCCAAATTTCTGTGCCGACAGAGCAGTGGGGAAAACTGTGACGTGGTCGTCA
ACACCCTGGGGAAGAGGGCCCCAGCCTTTGAGGGCAGGATCCTGCTCAACCCCCAGGACAAGGATGGCTCATTCAGTGTGGTGATCACAG
GCCTGAGGAAGGAGGATGCAGGGCGCTACCTGTGTGGAGCCCATTCGGATGGTCAGCTGCAGGAAGGCTCGCCTATCCAGGCCTGGCAAC
TCTTCGTCAATGAGGAGTCCACGATTCCCCGCAGCCCCACTGTGGTGAAGGGGGTGGCAGGAGGCTCTGTGGCCGTGCTCTGCCCCTACA
ACCGTAAGGAAAGCAAAAGCATCAAGTACTGGTGTCTCTGGGAAGGGGCCCAGAATGGCCGCTGCCCCCTGCTGGTGGACAGCGAGGGGT
GGGTTAAGGCCCAGTACGAGGGCCGCCTCTCCCTGCTGGAGGAGCCAGGCAACGGCACCTTCACTGTCATCCTCAACCAGCTCACCAGCC
GGGACGCCGGCTTCTACTGGTGTCTGACCAACGGCGATACTCTCTGGAGGACCACCGTGGAGATCAAGATTATCGAAGGAGAACCAAACC
TCAAGGTACCAGGGAATGTCACGGCTGTGCTGGGAGAGACTCTCAAGGTCCCCTGTCACTTTCCATGCAAATTCTCCTCGTACGAGAAAT
ACTGGTGCAAGTGGAATAACACGGGCTGCCAGGCCCTGCCCAGCCAAGACGAAGGCCCCAGCAAGGCCTTCGTGAACTGTGACGAGAACA
GCCGGCTTGTCTCCCTGACCCTGAACCTGGTGACCAGGGCTGATGAGGGCTGGTACTGGTGTGGAGTGAAGCAGGGCCACTTCTATGGAG
AGACTGCAGCCGTCTATGTGGCAGTTGAAGAGAGGAAGGCAGCGGGGTCCCGCGATGTCAGCCTAGCGAAGGCAGACGCTGCTCCTGATG
AGAAGGTGCTAGACTCTGGTTTTCGGGAGATTGAGAACAAAGCCATTCAGGATCCCAGGCTTTTTGCAGAGGAAAAGGCGGTGGCAGATA
CAAGAGATCAAGCCGATGGGAGCAGAGCATCTGTGGATTCCGGCAGCTCTGAGGAACAAGGTGGAAGCTCCAGAGCGCTGGTCTCCACCC
TGGTGCCCCTGGGCCTGGTGCTGGCAGTGGGAGCCGTGGCTGTGGGGGTGGCCAGAGCCCGGCACAGGAAGAACGTCGACCGAGTTTCAA
TCAGAAGCTACAGGACAGACATTAGCATGTCAGACTTCGAGAACTCCAGGGAATTTGGAGCCAATGACAACATGGGAGCCTCTTCGATCA
CTCAGGAGACATCCCTCGGAGGAAAAGAAGAGTTTGTTGCCACCACTGAGAGCACCACAGAGACCAAAGAACCCAAGAAGGCAAAAAGGT
CATCCAAGGAGGAAGCCGAGATGGCCTACAAAGACTTCCTGCTCCAGTCCAGCACCGTGGCCGCCGAGGCCCAGGACGGCCCCCAGGAAG
CCTAGACGGTGTCGCCGCCTGCTCCCTGCACCCATGACAATCACCTTCAGAATCATGTCGATCCTGGGGCCCTCAGCTCCTGGGGACCCC
ACTCCCTGCTCTAACACCTGCCTAGGTTTTTCCTACTGTCCTCAGAGGCGTGCTGGTCCCCTCCTCAGTGACATCAAAGCCTGGCCTAAT
TGTTCCTATTGGGGATGAGGGTGGCATGAGGAGGTCCCACTTGCAACTTCTTTCTGTTGAGAGAACCTCAGGTACGGAGAAGAATAGAGG
TCCTCATGGGTCCCTTGAAGGAAGAGGGACCAGGGTGGGAGAGCTGATTGCAGAAAGGAGAGACGTGCAGCGCCCCTCTGCACCCTTATC
ATGGGATGTCAACAGAATTTTTCCCTCCACTCCATCCCTCCCTCCCGTCCTTCCCCTCTTCTTCTTTCCTTCCATCAAAAGATGTATTTG
AATTCATACTAGAATTCAGGTGCTTTGCTAGATGCTGTGACAGGTATGCCACCAACACTGCTCACAGCCTTTCTGAGGACACCAGTGAAA
GAAGCCACAGCTCTTCTTGGCGTATTTATACTCACTGAGTCTTAACTTTTCACCAGGGGTGCTCACCTCTGCCCCTATTGGGAGAGGTCA
TAAAATGTCTCGAGTCCTAAGGCCTTAGGGGTCATGTATGATGAGCATACACACAGGTAATTATAAACCCACATTCTTACCATTTCACAC
ATAAGAAAATTGAGGTTTGGAAGAGTGAAGCGTTTTTCTTTTTCTTTTTTTTTTTTGAGACGGAGTCTCTCACTGTCGCCCAGGCTGGAG
TGCAGTGGCGCAATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTGACACCATTCTCCTGCCTCACCCTCCCAAGTAGCTGGGACTACA
GGCGCCTGCCAGCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGAC
CTCGTGATCCGCCTGCCTCTGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGTCCGGCCTCTTTTTTTCTTTTCTTTTTTTT
GAGACAAAGTCTCACTGTGTCACCCAGACTGGAATGCAGTGACACAATCTCGGCTCACTGAAACCTCTGCCTTCCAGGTTCAAGCTATTC
TCATGCCTCAGCCTCTCAAGTAGCTGGGACTACAGATGTGGGCCACCATGTCTGGCTAATTTTTTTTTTTTTTTTTTTTTTTTGTAGAGA
CAGGGTTTCGCCATGTTGACGAGACTGGTCTCGAACTCCTGGCCTCAAGTGATCTGCCGCCTCAGCTTCTCAAAGTACTGGGATTATATA
GGCATGAGCCACTGAGCCTGGCCCTGAAGCGTTTTTCTCAAAGGCCCTCAGTGAGATAAATTAGATTTGGCATCTCCTGTCCTGGGCCAG
GGATCTCTCTACAAGAGCCCCTGCCCCTCTGTTGGAGGCACAGTTTTAGAATAAGGAGGAGGAGGGAGAAGAGAAAATGTAAAGGAGGGA
GATCTTTCCCAGGCCGCACCATTTCTGTCACTCACATGGACCCAAGATAAAAGAATGGCCAAACCCTCACAACCCCTGATGTTTGAAGAG
TTCCAAGTTGAAGGGAAACAAAGAAGTGTTTGATGGTGCCAGAGAGGGGCTGCTCTCCAGAAAGCTAAAATTTAATTTCTTTTTTCCTCT
GAGTTCTGTACTTCAACCAGCCTACAAGCTGGCACTTGCTAACAAATCAGAAATATGACAATTAATGATTAAAGACTGTGATTGCCACCA

>83414_83414_4_SLC5A1-PIGR_SLC5A1_chr22_32495342_ENST00000543737_PIGR_chr1_207119808_ENST00000356495_length(amino acids)=875AA_BP=50
MASASPGCPLCSQHKVGNSSITSSPSPVTWDHPLRLSSCLLFSGRESMSQSRVSVLAAASSALPVAPREAGVTNWPAGCVPEVRSTGEKE
VAKTLHRRSRPEWCGARDPPAMLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLIS
SEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENA
QKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDL
RGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPI
QAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILN
QLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFVN
CDENSRLVSLTLNLVTRADEGWYWCGVKQGHFYGETAAVYVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQDPRLFAEEK
AVADTRDQADGSRASVDSGSSEEQGGSSRALVSTLVPLGLVLAVGAVAVGVARARHRKNVDRVSIRSYRTDISMSDFENSREFGANDNMG

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SLC5A1-PIGR

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for SLC5A1-PIGR

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for SLC5A1-PIGR

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source