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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ATRX-REPS2 (FusionGDB2 ID:8359)

Fusion Gene Summary for ATRX-REPS2

check button Fusion gene summary
Fusion gene informationFusion gene name: ATRX-REPS2
Fusion gene ID: 8359
HgeneTgene
Gene symbol

ATRX

REPS2

Gene ID

546

9185

Gene nameATRX chromatin remodelerRALBP1 associated Eps domain containing 2
SynonymsJMS|MRX52|RAD54|RAD54L|XH2|XNP|ZNF-HXPOB1
Cytomap

Xq21.1

Xp22.2

Type of geneprotein-codingprotein-coding
Descriptiontranscriptional regulator ATRXATP-dependent helicase ATRXX-linked helicase IIX-linked nuclear proteinalpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)ralBP1-associated Eps domain-containing protein 2RALBP1-interacting protein 2partner of Ral-binding protein 1partner of RalBP1
Modification date2020031320200313
UniProtAcc

P46100

.
Ensembl transtripts involved in fusion geneENST00000373344, ENST00000395603, 
ENST00000480283, ENST00000373341, 
ENST00000469714, ENST00000303843, 
ENST00000357277, ENST00000380064, 
Fusion gene scores* DoF score17 X 13 X 9=19896 X 6 X 4=144
# samples 236
** MAII scorelog2(23/1989*10)=-3.11233750988937
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/144*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATRX [Title/Abstract] AND REPS2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATRX(76776266)-REPS2(17151947), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneATRX

GO:0006334

nucleosome assembly

20651253

HgeneATRX

GO:0006338

chromatin remodeling

20651253


check buttonFusion gene breakpoints across ATRX (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across REPS2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-D7-5577-01AATRXchrX

76776266

-REPS2chrX

17151947

+


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Fusion Gene ORF analysis for ATRX-REPS2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000373344ENST00000469714ATRXchrX

76776266

-REPS2chrX

17151947

+
5CDS-3UTRENST00000395603ENST00000469714ATRXchrX

76776266

-REPS2chrX

17151947

+
5UTR-3CDSENST00000480283ENST00000303843ATRXchrX

76776266

-REPS2chrX

17151947

+
5UTR-3CDSENST00000480283ENST00000357277ATRXchrX

76776266

-REPS2chrX

17151947

+
5UTR-3CDSENST00000480283ENST00000380064ATRXchrX

76776266

-REPS2chrX

17151947

+
5UTR-3UTRENST00000480283ENST00000469714ATRXchrX

76776266

-REPS2chrX

17151947

+
In-frameENST00000373344ENST00000303843ATRXchrX

76776266

-REPS2chrX

17151947

+
In-frameENST00000373344ENST00000357277ATRXchrX

76776266

-REPS2chrX

17151947

+
In-frameENST00000373344ENST00000380064ATRXchrX

76776266

-REPS2chrX

17151947

+
In-frameENST00000395603ENST00000303843ATRXchrX

76776266

-REPS2chrX

17151947

+
In-frameENST00000395603ENST00000357277ATRXchrX

76776266

-REPS2chrX

17151947

+
In-frameENST00000395603ENST00000380064ATRXchrX

76776266

-REPS2chrX

17151947

+
intron-3CDSENST00000373341ENST00000303843ATRXchrX

76776266

-REPS2chrX

17151947

+
intron-3CDSENST00000373341ENST00000357277ATRXchrX

76776266

-REPS2chrX

17151947

+
intron-3CDSENST00000373341ENST00000380064ATRXchrX

76776266

-REPS2chrX

17151947

+
intron-3UTRENST00000373341ENST00000469714ATRXchrX

76776266

-REPS2chrX

17151947

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000373344ATRXchrX76776266-ENST00000357277REPS2chrX17151947+13611741521578192534
ENST00000373344ATRXchrX76776266-ENST00000303843REPS2chrX17151947+13611741521578192534
ENST00000373344ATRXchrX76776266-ENST00000380064REPS2chrX17151947+7961741521578192534
ENST00000395603ATRXchrX76776266-ENST00000357277REPS2chrX17151947+13497730121577052496
ENST00000395603ATRXchrX76776266-ENST00000303843REPS2chrX17151947+13497730121577052496
ENST00000395603ATRXchrX76776266-ENST00000380064REPS2chrX17151947+7847730121577052496

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000373344ENST00000357277ATRXchrX76776266-REPS2chrX17151947+0.00040390.99959606
ENST00000373344ENST00000303843ATRXchrX76776266-REPS2chrX17151947+0.00040390.99959606
ENST00000373344ENST00000380064ATRXchrX76776266-REPS2chrX17151947+0.0011759940.99882394
ENST00000395603ENST00000357277ATRXchrX76776266-REPS2chrX17151947+0.0004024520.9995976
ENST00000395603ENST00000303843ATRXchrX76776266-REPS2chrX17151947+0.0004024520.9995976
ENST00000395603ENST00000380064ATRXchrX76776266-REPS2chrX17151947+0.0011703710.99882966

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Fusion Genomic Features for ATRX-REPS2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ATRXchrX76776265-REPS2chrX17151946+0.0005752010.9994248
ATRXchrX76776265-REPS2chrX17151946+0.0005752010.9994248

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ATRX-REPS2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:76776266/chrX:17151947)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATRX

P46100

.
FUNCTION: Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase activity and catalyzes the replication-independent deposition of histone H3.3 in pericentric DNA repeats outside S-phase and telomeres, and the in vitro remodeling of H3.3-containing nucleosomes. Its heterochromatin targeting is proposed to involve a combinatorial readout of histone H3 modifications (specifically methylation states of H3K9 and H3K4) and association with CBX5. Involved in maintaining telomere structural integrity in embryonic stem cells which probably implies recruitment of CBX5 to telomeres. Reports on the involvement in transcriptional regulation of telomeric repeat-containing RNA (TERRA) are conflicting; according to a report, it is not sufficient to decrease chromatin condensation at telomeres nor to increase expression of telomeric RNA in fibroblasts (PubMed:24500201). May be involved in telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines. Acts as negative regulator of chromatin incorporation of transcriptionally repressive histone MACROH2A1, particularily at telomeres and the alpha-globin cluster in erythroleukemic cells. Participates in the allele-specific gene expression at the imprinted IGF2/H19 gene locus. On the maternal allele, required for the chromatin occupancy of SMC1 and CTCTF within the H19 imprinting control region (ICR) and involved in esatblishment of histone tails modifications in the ICR. May be involved in brain development and facial morphogenesis. Binds to zinc-finger coding genes with atypical chromatin signatures and regulates its H3K9me3 levels. Forms a complex with ZNF274, TRIM28 and SETDB1 to facilitate the deposition and maintenance of H3K9me3 at the 3' exons of zinc-finger genes (PubMed:27029610). {ECO:0000269|PubMed:12953102, ECO:0000269|PubMed:14990586, ECO:0000269|PubMed:20504901, ECO:0000269|PubMed:20651253, ECO:0000269|PubMed:21029860, ECO:0000269|PubMed:22391447, ECO:0000269|PubMed:22829774, ECO:0000269|PubMed:24500201, ECO:0000269|PubMed:27029610}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351151_115624002493.0Compositional biasNote=Poly-Ser
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351166_116924002493.0Compositional biasNote=Poly-Lys
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351202_120624002493.0Compositional biasNote=Poly-Ser
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351259_126624002493.0Compositional biasNote=Poly-Asp
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351443_146624002493.0Compositional biasNote=Poly-Glu
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351499_150224002493.0Compositional biasNote=Poly-Glu
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351929_193924002493.0Compositional biasNote=Poly-Lys
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351941_194824002493.0Compositional biasNote=Poly-Ser
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34352222_222524002493.0Compositional biasNote=Poly-Lys
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34352262_226524002493.0Compositional biasNote=Poly-Glu
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-3435745_75024002493.0Compositional biasNote=Poly-Ser
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341151_115623622455.0Compositional biasNote=Poly-Ser
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341166_116923622455.0Compositional biasNote=Poly-Lys
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341202_120623622455.0Compositional biasNote=Poly-Ser
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341259_126623622455.0Compositional biasNote=Poly-Asp
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341443_146623622455.0Compositional biasNote=Poly-Glu
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341499_150223622455.0Compositional biasNote=Poly-Glu
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341929_193923622455.0Compositional biasNote=Poly-Lys
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341941_194823622455.0Compositional biasNote=Poly-Ser
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33342222_222523622455.0Compositional biasNote=Poly-Lys
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33342262_226523622455.0Compositional biasNote=Poly-Glu
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-3334745_75023622455.0Compositional biasNote=Poly-Ser
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351581_176824002493.0DomainHelicase ATP-binding
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-3435159_29624002493.0DomainADD
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34352025_220524002493.0DomainHelicase C-terminal
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341581_176823622455.0DomainHelicase ATP-binding
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-3334159_29623622455.0DomainADD
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33342025_220523622455.0DomainHelicase C-terminal
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351719_172224002493.0MotifNote=DEGH box
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-3435581_59424002493.0MotifNote=PxVxL motif
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341719_172223622455.0MotifNote=DEGH box
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-3334581_59423622455.0MotifNote=PxVxL motif
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351594_160124002493.0Nucleotide bindingATP
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341594_160123622455.0Nucleotide bindingATP
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-3435170_20624002493.0Zinc fingerGATA-type%3B atypical
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-3435217_27224002493.0Zinc fingerPHD-type%3B atypical
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-3334170_20623622455.0Zinc fingerGATA-type%3B atypical
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-3334217_27223622455.0Zinc fingerPHD-type%3B atypical
TgeneREPS2chrX:76776266chrX:17151947ENST000003038431318601_657525660.0Coiled coilOntology_term=ECO:0000255
TgeneREPS2chrX:76776266chrX:17151947ENST000003572771318601_657526661.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34352420_242524002493.0Compositional biasNote=Poly-Gln
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33342420_242523622455.0Compositional biasNote=Poly-Gln
TgeneREPS2chrX:76776266chrX:17151947ENST000003038431318328_339525660.0Calcium bindingOntology_term=ECO:0000255
TgeneREPS2chrX:76776266chrX:17151947ENST000003572771318328_339526661.0Calcium bindingOntology_term=ECO:0000255
TgeneREPS2chrX:76776266chrX:17151947ENST0000030384313183_76525660.0Compositional biasNote=Ala-rich
TgeneREPS2chrX:76776266chrX:17151947ENST000003038431318477_524525660.0Compositional biasNote=Pro-rich
TgeneREPS2chrX:76776266chrX:17151947ENST0000035727713183_76526661.0Compositional biasNote=Ala-rich
TgeneREPS2chrX:76776266chrX:17151947ENST000003572771318477_524526661.0Compositional biasNote=Pro-rich
TgeneREPS2chrX:76776266chrX:17151947ENST000003038431318282_373525660.0DomainEH 2
TgeneREPS2chrX:76776266chrX:17151947ENST000003038431318315_350525660.0DomainEF-hand
TgeneREPS2chrX:76776266chrX:17151947ENST00000303843131834_147525660.0DomainEH 1
TgeneREPS2chrX:76776266chrX:17151947ENST000003572771318282_373526661.0DomainEH 2
TgeneREPS2chrX:76776266chrX:17151947ENST000003572771318315_350526661.0DomainEF-hand
TgeneREPS2chrX:76776266chrX:17151947ENST00000357277131834_147526661.0DomainEH 1


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Fusion Gene Sequence for ATRX-REPS2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8359_8359_1_ATRX-REPS2_ATRX_chrX_76776266_ENST00000373344_REPS2_chrX_17151947_ENST00000303843_length(transcript)=13611nt_BP=7415nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGTGAAAGCAAGTTGAATACATTGGTGCAGAAGCTTC
ATGACTTCCTTGCACACTCATCAGAAGAATCTGAAGAAACAAGTTCTCCTCCACGACTTGCAATGAATCAAAACACAGATAAAATCAGTG
GTTCTGGAAGTAACTCTGATATGATGGAAAACAGCAAGGAAGAGGGAACTAGCTCTTCAGAAAAATCCAAGTCTTCAGGATCGTCACGAT
CAAAGAGGAAACCTTCAATTGTAACAAAGTATGTAGAATCAGATGATGAAAAACCTTTGGATGATGAAACTGTAAATGAAGATGCGTCTA
ATGAAAATTCAGAAAATGATATTACTATGCAGAGCTTGCCAAAAGGTACAGTGATTGTACAGCCAGAGCCAGTGCTGAATGAAGACAAAG
ATGATTTTAAAGGGCCTGAATTTAGAAGCAGAAGTAAAATGAAAACTGAAAATCTCAAAAAACGCGGAGAAGATGGGCTTCATGGGATTG
TGAGCTGCACTGCTTGTGGACAACAGGTCAATCATTTTCAAAAAGATTCCATTTATAGACACCCTTCATTGCAAGTTCTTATTTGTAAGA
ATTGCTTTAAGTATTACATGAGTGATGATATTAGCCGTGACTCAGATGGAATGGATGAACAATGTAGGTGGTGTGCGGAAGGTGGAAACT
TGATTTGTTGTGACTTTTGCCATAATGCTTTCTGCAAGAAATGCATTCTACGCAACCTTGGTCGAAAGGAGTTGTCCACAATAATGGATG
AAAACAACCAATGGTATTGCTACATTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAACAGCGTATTTGAGAATTTAGAAC
AGTTGTTGCAGCAAAATAAGAAGAAGATAAAAGTTGACAGTGAAAAGAGTAATAAAGTATATGAACATACATCCAGATTTTCTCCAAAGA
AGACTAGTTCAAATTGTAATGGAGAAGAAAAGAAATTAGATGATTCCTGTTCTGGCTCTGTAACCTACTCTTATTCCGCACTAATTGTGC
CCAAAGAGATGATTAAGAAGGCAAAAAAACTGATTGAGACCACAGCCAACATGAACTCCAGTTATGTTAAATTTTTAAAGCAGGCAACAG
ATAATTCAGAAATCAGTTCTGCTACAAAATTACGTCAGCTTAAGGCTTTTAAGTCTGTGTTGGCTGATATTAAGAAGGCTCATCTTGCAT
TGGAAGAAGACTTAAATTCCGAGTTTCGAGCGATGGATGCTGTAAACAAAGAGAAAAATACCAAAGAGCATAAAGTCATAGATGCTAAGT
TTGAAACAAAAGCACGAAAAGGAGAAAAACCTTGTGCTTTGGAAAAGAAGGATATTTCAAAGTCAGAAGCTAAACTTTCAAGAAAACAGG
TAGATAGTGAGCACATGCATCAGAATGTTCCAACAGAGGAACAAAGAACAAATAAAAGTACCGGTGGTGAACATAAGAAATCTGATAGAA
AAGAAGAACCTCAATATGAACCTGCCAACACTTCTGAAGATTTAGACATGGATATTGTGTCTGTTCCTTCCTCAGTTCCAGAAGACATTT
TTGAGAATCTTGAGACTGCTATGGAAGTTCAGAGTTCAGTTGATCATCAAGGGGATGGCAGCAGTGGAACTGAACAAGAAGTGGAGAGTT
CATCTGTAAAATTAAATATTTCTTCAAAAGACAACAGAGGAGGTATTAAATCAAAAACTACAGCTAAAGTAACAAAAGAATTATATGTTA
AACTCACTCCTGTTTCCCTTTCTAATTCCCCAATTAAAGGTGCTGATTGTCAGGAAGTTCCACAAGATAAAGATGGCTATAAAAGTTGTG
GTCTGAACCCCAAGTTAGAGAAATGTGGACTTGGACAGGAAAACAGTGATAATGAGCATTTGGTTGAAAATGAAGTTTCATTACTTTTAG
AGGAATCTGATCTTCGAAGATCCCCACGTGTAAAGACTACACCCTTGAGGCGACCGACAGAAACTAACCCTGTAACATCTAATTCAGATG
AAGAATGTAATGAAACAGTTAAGGAGAAACAAAAACTATCAGTTCCAGTGAGAAAAAAGGATAAGCGTAATTCTTCTGACAGTGCTATAG
ATAATCCTAAGCCTAATAAATTGCCAAAATCTAAGCAATCAGAGACTGTGGATCAAAATTCAGATTCTGATGAAATGCTAGCAATCCTCA
AAGAGGTGAGCAGGATGAGTCACAGTTCTTCTTCAGATACTGATATTAATGAAATTCATACAAACCATAAGACTTTGTATGATTTAAAGA
CTCAGGCGGGGAAAGATGATAAAGGAAAAAGGAAACGAAAAAGTTCTACATCTGGCTCAGATTTTGATACTAAAAAGGGCAAATCAGCTA
AGAGCTCTATAATTTCTAAAAAGAAACGACAAACCCAGTCTGAGTCTTCTAATTATGACTCAGAATTAGAAAAAGAGATAAAGAGCATGA
GTAAAATTGGTGCTGCCAGAACCACCAAAAAAAGAATTCCAAATACAAAAGATTTTGACTCTTCTGAAGATGAGAAACACAGCAAAAAAG
GAATGGATAATCAAGGGCACAAAAATTTGAAGACCTCACAAGAAGGATCATCTGATGATGCTGAAAGAAAACAAGAGAGAGAGACTTTCT
CTTCAGCAGAAGGCACAGTTGATAAAGACACGACCATCATGGAATTAAGAGATCGACTTCCTAAGAAGCAGCAAGCAAGTGCTTCCACTG
ATGGTGTCGATAAGCTTTCTGGGAAAGAGCAGAGTTTTACTTCTTTGGAAGTTAGAAAAGTTGCTGAAACTAAAGAAAAGAGCAAGCATC
TCAAAACCAAAACATGTAAAAAAGTACAGGATGGCTTATCTGATATTGCAGAGAAATTCCTAAAGAAAGACCAGAGCGATGAAACTTCTG
AAGATGATAAAAAGCAGAGCAAAAAGGGAACTGAAGAAAAAAAGAAACCTTCAGACTTTAAGAAAAAAGTAATTAAAATGGAACAACAGT
ATGAATCTTCATCTGATGGCACTGAAAAGTTACCTGAGCGAGAAGAAATTTGTCATTTTCCTAAGGGCATAAAACAAATTAAGAATGGAA
CAACTGATGGAGAAAAGAAAAGTAAAAAAATAAGAGATAAAACTTCTAAAAAGAAGGATGAATTATCTGATTATGCTGAGAAGTCAACAG
GGAAAGGAGATAGTTGTGACTCTTCAGAGGATAAAAAGAGTAAGAATGGAGCATATGGTAGAGAGAAGAAAAGGTGCAAGTTGCTTGGAA
AGAGTTCAAGGAAGAGACAAGATTGTTCATCATCTGATACTGAGAAATATTCCATGAAAGAAGATGGTTGTAACTCTTCTGATAAGAGAC
TGAAAAGAATAGAATTGAGGGAAAGAAGAAATTTAAGTTCAAAGAGAAATACTAAGGAAATACAAAGTGGCTCATCATCATCTGATGCTG
AGGAAAGTTCTGAAGATAATAAAAAGAAGAAGCAAAGAACTTCATCTAAAAAGAAGGCAGTCATTGTCAAGGAGAAAAAGAGAAACTCCC
TAAGAACAAGCACTAAAAGGAAGCAAGCTGACATTACATCCTCATCTTCTTCTGATATAGAAGATGATGATCAGAATTCTATAGGTGAGG
GAAGCAGCGATGAACAGAAAATTAAGCCTGTGACTGAAAATTTAGTGCTGTCTTCACATACTGGATTTTGCCAATCTTCAGGAGATGAAG
CCTTATCTAAATCAGTGCCTGTCACAGTGGATGATGATGATGACGACAATGATCCTGAGAATAGAATTGCCAAGAAGATGCTTTTAGAAG
AAATTAAAGCCAATCTTTCCTCTGATGAGGATGGATCTTCAGATGATGAGCCAGAAGAAGGGAAAAAAAGAACTGGAAAACAAAATGAAG
AAAACCCAGGAGATGAGGAAGCAAAAAATCAAGTCAATTCTGAATCAGATTCAGATTCTGAAGAATCTAAGAAGCCAAGATACAGACATA
GGCTTTTGCGGCACAAATTGACTGTGAGTGACGGAGAATCTGGAGAAGAAAAAAAGACAAAGCCTAAAGAGCATAAAGAAGTCAAAGGCA
GAAACAGAAGAAAGGTGAGCAGTGAAGATTCAGAAGATTCTGATTTTCAGGAATCAGGAGTTAGTGAAGAAGTTAGTGAATCCGAAGATG
AACAGCGGCCCAGAACAAGGTCTGCAAAGAAAGCAGAGTTGGAAGAAAATCAGCGGAGCTATAAACAGAAAAAGAAAAGGCGACGTATTA
AGGTTCAAGAAGATTCATCCAGTGAAAACAAGAGTAATTCTGAGGAAGAAGAGGAGGAAAAAGAAGAGGAGGAGGAAGAGGAGGAGGAGG
AGGAAGAGGAGGAGGAAGATGAAAATGATGATTCCAAGTCTCCTGGAAAAGGCAGAAAGAAAATTCGGAAGATTCTTAAAGATGATAAAC
TGAGAACAGAAACACAAAATGCTCTTAAGGAAGAGGAAGAGAGACGAAAACGTATTGCTGAGAGGGAGCGTGAGCGAGAAAAATTGAGAG
AGGTGATAGAAATTGAAGATGCTTCACCCACCAAGTGTCCAATAACAACCAAGTTGGTTTTAGATGAAGATGAAGAAACCAAAGAACCTT
TAGTGCAGGTTCATAGAAATATGGTTATCAAATTGAAACCCCATCAAGTAGATGGTGTTCAGTTTATGTGGGATTGCTGCTGTGAGTCTG
TGAAAAAAACAAAGAAATCTCCAGGTTCAGGATGCATTCTTGCCCACTGTATGGGCCTTGGTAAGACTTTACAGGTGGTAAGTTTTCTTC
ATACAGTTCTTTTGTGTGACAAACTGGATTTCAGCACGGCGTTAGTGGTTTGTCCTCTTAATACTGCTTTGAATTGGATGAATGAATTTG
AGAAGTGGCAAGAGGGATTAAAAGATGATGAGAAGCTTGAGGTTTCTGAATTAGCAACTGTGAAACGTCCTCAGGAGAGAAGCTACATGC
TGCAGAGGTGGCAAGAAGATGGTGGTGTTATGATCATAGGCTATGAGATGTATAGAAATCTTGCTCAAGGAAGGAATGTGAAGAGTCGGA
AACTTAAAGAAATATTTAACAAAGCTTTGGTTGATCCAGGCCCTGATTTTGTTGTTTGTGATGAAGGCCATATTCTAAAAAATGAAGCAT
CTGCTGTTTCTAAAGCTATGAATTCTATACGATCAAGGAGGAGGATTATTTTAACAGGAACACCACTTCAAAATAACCTAATTGAGTATC
ATTGTATGGTTAATTTTATCAAGGAAAATTTACTTGGATCCATTAAGGAGTTCAGGAATAGATTTATAAATCCAATTCAAAATGGTCAGT
GTGCAGATTCTACCATGGTAGATGTCAGAGTGATGAAAAAACGTGCTCACATTCTCTATGAGATGTTAGCTGGATGTGTTCAGAGGAAAG
ATTATACAGCATTAACAAAATTCTTGCCTCCAAAACACGAATATGTGTTAGCTGTGAGAATGACTTCTATTCAGTGCAAGCTCTATCAGT
ACTACTTAGATCACTTAACAGGTGTGGGCAATAATAGTGAAGGTGGAAGAGGAAAGGCAGGTGCAAAGCTTTTCCAAGATTTTCAGATGT
TAAGTAGAATATGGACTCATCCTTGGTGTTTGCAGCTAGACTACATTAGCAAAGAAAATAAGGGTTATTTTGATGAAGACAGTATGGATG
AATTTATAGCCTCAGATTCTGATGAAACCTCCATGAGTTTAAGCTCCGATGATTATACAAAAAAGAAGAAAAAAGGGAAAAAGGGGAAAA
AAGATAGTAGCTCAAGTGGAAGTGGCAGTGACAATGATGTTGAAGTGATTAAGGTCTGGAATTCAAGATCTCGGGGAGGTGGTGAAGGAA
ATGTGGATGAAACAGGAAACAATCCTTCTGTTTCTTTAAAACTGGAAGAAAGTAAAGCTACTTCTTCTTCTAATCCAAGCAGCCCAGCTC
CAGACTGGTACAAAGATTTTGTTACAGATGCTGATGCTGAGGTTTTAGAGCATTCTGGGAAAATGGTACTTCTCTTTGAAATTCTTCGAA
TGGCAGAGGAAATTGGGGATAAAGTCCTTGTTTTCAGCCAGTCCCTCATATCTCTGGACTTGATTGAAGATTTTCTTGAATTAGCTAGTA
GGGAGAAGACAGAAGATAAAGATAAACCCCTTATTTATAAAGGTGAGGGGAAGTGGCTTCGAAACATTGACTATTACCGTTTAGATGGTT
CCACTACTGCACAGTCAAGGAAGAAGTGGGCTGAAGAATTTAATGATGAAACTAATGTGAGAGGACGATTATTTATCATTTCTACTAAAG
CAGGATCTCTAGGAATTAATCTGGTAGCTGCTAATCGAGTAATTATATTCGACGCTTCTTGGAATCCATCTTATGACATCCAGAGTATAT
TCAGAGTTTATCGCTTTGGACAAACTAAGCCTGTTTATGTATATAGGTTCTTAGCTCAGGGAACCATGGAAGATAAGATTTATGATCGGC
AAGTAACTAAGCAGTCACTGTCTTTTCGAGTTGTTGATCAGCAGCAGGTGGAGCGTCATTTTACTATGAATGAGCTTACTGAACTTTATA
CTTTTGAGCCAGACTTATTAGATGACCCTAATTCAGAAAAGAAGAAGAAGAGGGATACTCCCATGCTGCCAAAGGATACCATACTTGCAG
AGCTCCTTCAGATACATAAAGAACACATTGTAGGATACCATGAACATGATTCTCTTTTGGACCACAAAGAAGAAGAAGAGTTGACTGAAG
AAGAAAGAAAAGCAGCTTGGGCTGAGTATGAAGCAGAGAAGAAGGGACTGACCATGCGTTTCAACATACCAACTGGGACCAATTTACCCC
CTGTCAGTTTCAACTCTCAAACTCCTTATATTCCTTTCAATTTGGGAGCCCTGTCAGCAATGAGTAATCAACAGCTGGAGGACCTCATTA
ATCAAGGAAGAGAAAAAGTTGTAGAAGCAACAAACAGTGTGACAGCAGTGAGGATTCAACCTCTTGAGGATATAATTTCAGCTGTATGGA
AGGAGAACATGAATCTCTCAGAGGCCCAAGTACAGGCGTTAGCATTAAGTAGACAAGCCAGCCAGGAGCTTGATGTTAAACGAAGAGAAG
CAATCTACAATGATGTATTGACAAAACAACAGATGTCTGAACAAGTGTCGGAGGCCGAGTTACTCCCACAGCTGAGCAGAGCCCCATCCC
AGGCTGCAGAAAGTAGTCCAGCAAAGAAGGATGTACTGTATTCTCAGCCACCATCAAAGCCCATTCGTAGGAAATTCAGACCAGAAAACC
AAGCTACAGAAAACCAAGAGCCTTCCACTGCTGCAAGTGGGCCAGCTTCTGCGGCAACCATGAAACCGCATCCAACAGTCCAAAAGCAGT
CTTCCAAACAGAAGAAGGCCATTCAAACTGCTATCCGCAAAAATAAAGAGGCAAACGCAGTGCTGGCTCGGCTGAACAGTGAGCTCCAGC
AGCAGCTCAAGGAGGTTCATCAAGAACGAATTGCATTGGAAAACCAATTGGAACAACTTCGTCCGGTCACTGTGTTGTGACCCCCCCATG
GTTCAAGTGACAGTGGGTGACCTTGTCTGCCAAGATCTTTCTTTTGAATGTTTTGAACCCAACTACTTGTCATAGATGTTTGACTGTGTC
AAAAGCTGTGAGCAGCAAAATATAATCCATATGACCTTTTCTCTTGCACTTCACTTGTATGTTTTACTGTGGTGGAAAAAATACTTCAAC
TGATTATCACACTTGAAATGCTAATTATCAGTGGAATTTGTCTCCTATTCTTAAGTACTTCTGCAAGGTATTAGATGCTGCTCCTTACCA
AAAATCAGTCTTCTAGCAAATAAAAATAACTTAGAGCATTATTTATTTAAAGAATTTATGTTTTCTATAAAACCTTATAACCAAGAACCT
TCAGGATGCTTGTAACCAAGTACTTTCAGGATGCTTTTTGTATGTATATCACATAGAGTAGGTTGGTTTCCTGAGTAATTGGGATTCCAA
CTAGATAGTCATTGGTGTGACCATAATAAAAACAAAAGCTAAAATAAAAGCATCAGATTTAGACTGGCGCTGTGCCCTCTACCACTATAT
GCCAAAAATTGCTTCTCTAGTGCCATTTTGATATTATATCTAGCTATAAATAATACATGACTATCGTTTTCTATTGAATGTCAAAGACTT
ACTGGGTCTTTACACCTCTGTAAAGTGGAGGTTTTGGCAATGAGCTGTTTAACTTGGCCAAGCTAGGCTGTCAACCCAGACAACTCAGTC
CTTTCATGTAAATTTTTGGGCAAGAGAAGTCTGCTTTGACTGCCTTGCCTGACCAAATTAAATAAATAGTTGCCAGATCTCTACTTTTAT
CCTGCATGGGATAATATATCTGTAAATGCATGAGTTTGGAAACCACCCATCAAATATGAAAGGCTGATGAGACTGTTAGGATTGATAAAC
ATTTGTTGTTTGAACCCAGCTATCCAAACTGGGGAAGAAGGGGAAATGGTTGTTACCAACAATCTCTAGTAGTTATTTTAATCTTTATTT
TAACCTGGATTGCAAATGTATGGGGTATGAGGAGATAATGAAAGAAAAGTGGTCCTCATGCTGGATATGTGACTGTTTTGTTCTCTGTAA
AGTGTATTCTTGGGAAGTGATTGGTTTATATCAGATTCAGAGGAGCCCAATTAACTCCAGTGTAGGTAATGTAAAACAGTAAGCTCAAAT
TGCAGAAGCCAGTATCCTACAGAAATTTAAGTAGCTACTGCTTCTCCTGAAAGCCCAAGTTGAAAATGGGACCACAGGGGCACAGGGCTA
CTGACCCTCACAGGGCATGCCAGCGTTAACACCACTTTGAGAGACCAATGGCAAGAAATGCTGTCTCTTGTGCATTTTACTAATTTCCCC
ATTCTTAGGGTAGCAGGGTGGGGGTGTATAGGGTCTTTTTGAAGCAGTTTTGGATAGGTTTGCAATATGTGGGATTCAGCCTTTGATTTC
AATAGAGCTGAGAGCTTTTAGAACAAGCAGGCATTTATTTAATGTTTCCTTAGTCCATTGGCAAGCTTTATCAATAGCTTAATGGCAGAG
GATAAAGGCTCAAACAGATGATGTTTTTTCCACAGAAAAACAAATTGTTGAATCTATTCCGTGCATATTTAAGGATTTTGAATTGATTTT
GAAAATCATGAAACTTGAACTATTTTTCTATTCCCTTTTTTTCTTCCCCATTTGCTGCCTTTTTTGTTTTTGTGGGGGAAGGGTTGGGAG
TAAGTTTAAACTCTTCCGAAGATTATGAATGGGTCAGCACAAATTTTTAGGCAACTGCTTTTTCCATGTTCTGAGATCTACGGGCTACAA
CAAATTTTATCAGCAGTGTTTTTTGTTTTTTTGAGATGGAGACTTGCTCTGTCGCCCAGGCTGGAGCGCAGTGGCGCAATCTCGGCTCAC
TGCAACCTCCACCTCCTGGGTTCAAGCAATTCTTGTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCCACCACCACGCTCAGCTA
ATTTTTGTATTTTTAGTAGAGATGGGATTTTGTCATGTTGGCTAGGCTAGTCTCGAATTCCTGACCTCAAGTGATCCACCCGCCTTGGCC
TCTCGAAGTGCTGGGATTACAGGCGTGAGCCACCCGCCCGGCTATCAGCACTGTTCTGATTGCAGACGTTTCACAGCATGTTTGGCTTTT
GGTAAATTCAATCCAGGAAAGACTAGCATGTGCACTTTATCTCATAATCTTCCAGTACATATGCTCTCAGTTGGGATAGCAGTTCATTTC
CATTAGGCAGACGTATAAACTAAGGAATGTTAGTCTGCAGTATTCATTTTAAAAATATTGACATGCTTTTCCCCTCCCCTCCATGAAGTC
AGTGCCAGAGTGAGCCAGATTGGGAGGTTGGGGTTTTGTTTGGTTGGCTTGGTTTTCATTAAGGGAAAAAACTTGCATTGGACAATCAAA
TTCCCCTGAGTTTCATAATCTCATCAATATTTTAAGATAGGCGAGCACACACTAATAATATCTATGCCTACCTTCTTGGGTGGACTCAAC
TGTAACCACAGTTTATTAGTTGCTTAGAAGTGGATTTTTAAAAAACAGTTAAATGTGTGTGCATAACACACAAGTAATGACACACTACTA
TTATTATTACCTAAGTAGTGCTCATCCTCTCTTTCTGTGTTTTCTTAGGATGTGCACTTTAATTTAGGATTGTAACGCCTAATAATATTT
CTGTGAGCCTTTAATGTGATTTATAAGATGGCCGAATTACTGAAATCACCATTATACCTCTTCCATAAAACGACTCCAAAGTTAGACCTG
CCTGTTGGGGAGAATTCTATAGACAGAAGGTCAATGTTGTCCCCATCCATAGGGGTTGAATTACCTTGCTGTTAAGTGGTCTTCCCCCAT
TGGGATCCTACAGTCCCACAGATGAAAGCACAGTAGTAGCTGACAGCTGGCTTATTTGGTCCCTCGGCATCTCTCGTATGTGGCATATTG
CTTTTGCCACTTTCCTATCCAGCAGACATCAAAGCAAAACTAAAAGGTAGATATCTGGAATGAATGTATATGTTGTAATTGAGGCAGATA
TTTGCCTTAATTGGAAGGATCTAACTGCTTTACAAATATTAAACAAGTGCTTGGGCATGATTGGGAGAGGAGGCAGCTTAGCTGGAAGCT
GTGCCCATCTTACTGTCACTGGAGAATAGGATGTCAGAGCTGGGCAGGACTGGTACCCATCATTTGCAGTTTGCATGTGGGGAAACCAAA
GCCCTAAGAAACAACAGTTCCTGGCCCAAAAAATCCATAGAAAGAGGTAACTAGTGGCAGATTTGGGGCGCCAACCTGATTTTATGGATT
TTGAGTTAGATTCTCTACCCTCTATCAATACTAAAAATAGATTAGGAGGGTTTTTTTTTCTGTTTATCATGTTGAATTTCATTGACTTAA
TTAGTCTTTAAATTTGAAAACATGTTTTAGGGAGTTTAGTTCTAGAAATTTCTCTTAGATTGAAGTGACAGAATCTGAAAGAAAAGAATA
TGATTGAGCTATTTGTTTTCCTGAACACCTCACCTTTTATGATGCAATAAGTTACTCTGAGTTTCTTGGCAGAGTTTTTGACAGCTGTTG
CTTTCAATGGATTCCATTCCTGTATTCCTTATGGGAGGTTGTTTTTAAAATAGACTACTGCGATTGAAATGAACTCAATATGTAGTTAAG
TTATAGTTTTCTTCAATGTATTTTTAGTTACTTGGGTCACAAATGTTCAATTTCAGCATATTTTAGGGTGAGTAATCAAAAATGTGAATT
TGCCTTTGATTTCCTACCACTGTCTGAGCTATCATAAAGCATTCTCTTTAGTTGTGATTTGATTCTATAGTCTGTTTCTAAATGACATTT
GTCTGTTTCTTAAATGATCTCACAGCCATGGTAATAATAGATGTGTACTCAGAAGATCAATAAGGTAATATTGGAATTCATGTGTTTTTT
GCAATTAAGGCAGGCATTTGCCAATGTCTTCTTTTAAGCAGTAGTTGGAAACATCTCAATTACAGTGTAACACCTTAGAGCTAAAAACAT
TTGTTCAACACAAACTAGAATCACACCTTCTCACTAGATATCACCAAGGGAATGTGGTTTTAAAAATAAAAAGAAAACAATATAACGTAT
CATGGCAACCAGAGCTTCCCATATTATTGACAAGTAGGGATCATTAGGTTCTGGTTTGAACATTCTGAATGTGAACAAAATGAAATAGTA
GTTAAGAGGTGTTTTCCCACTGTGTTTAAAGAGAACACTAGTAATTCTGGTTTTTCTTTCTAACTGCTTTACTGTTTCAAGGGTATTCTT
TTAAAACTCTGATTTCAAAGGATCAGTTGAATTTATACTTTAGTTATGGGTGTTTTGTTACTTTTTTTTTTTTTGTATCATGACTCAGTA
TGGTTCAATTTCCTAGTAAGAAGTGGGGATTTGTGTTTTTGGAGTCCTCAGCTCACATGTCTTGTTCCTCCTTCAGCACAAGCTAGGGGA
GATCCTACCAACACTGATAGGTCAGTCATTGATGGCAATTTGAATGTGGGTATTACTCTGTGAGCCACCCTGCTTCGCTTGTTTGTAAGG
AGAAATGCATCTGGTTATGTGAATTTCCCGAGAGCAGCAGACATGGAGGGCCAGACTTTAAAAGCAACGCAAGCAGATTCGAAGAGCTGT
TGCCCTCTTCTAAAAAAGGCTTTTGGAGGCTGTGTTACATGCATGCCCTAAAGCAGTCAGTCTGTTAGTATGAGCAAGACATCTGAAGTA
CACAGTTGCTTTTAGGCTTGTATAGTTATTTTCTACACATGCCAACACACATGATGATAAAGGAACCTTTTCTAGGAGGCATTGCAGGGT
TTCAATACACAGGACATGTTCTAGTTACAGAAGCCTTGCTCTGCTGTCAACAATTGGGAAATGCTCATTTTTTCATGTTTTGTGAATACT
CTGGTCTTGCTGTAAGCTAATGTCATGGCTGTGGGATATTAGAGAAGTGGGTTTATGACTCTGAAGACCAGCAGACACCAGACTTTAAAA
GTGCTTAAATTGGAATTTGGAAACTACAGTAAAGAAACCTTCAGATACCAGTTCCATCCTGAAGCCCTCTGTTGAACAACAGGGCCAGAT
CCTAAAGCTCTTTCAGGGAGCTCTTCTCTGGGGCTGGAACAGTTGATTATGCAACCCCATTGTGTGGAGATTGGATCAACTGAGTTGTGT
TATTTTTGTTTTAAGTCACCTTGTGCGAGAACCTCAACCGCACCTATCTTGGGAACCGGGTATACCCTTTTCTTTAGCACTGCTATCCTT
TTTGTCTTCAGCACAAATAAGATGTTCAAGTGAGCCAGAAGCAAGAAGAGCCATTTTAGTCTTCATAGCTATTGGCTAAGAGAGATAATG
AGCTGATGGTCTATTTTAACCTTGAAAGTAAAAATGTATATTTTTTCACTACAAGTACATTGAACAGTAAAAAGTGTAACAGCAAAGTAT
ATATTTGATGCCTTCTGTCTTTTCATGATAATGTGCTAACAAGTTGTGTTAATATTTTACTCAGCCAGAGTCTCATTCATTTGCTAAGCA
TTGGGAACATTATGTATATTGACCTTAAACATAGGTGTCCTATATTTGGATTGTGACTTGTAGACTCAAGCTAACCTTACTGCCTCTTTT
TCACACTTGTTGAAAAGTCTGTGAAGAACATAGTTAAAGATCTCCAACTTTGGAAAATATACATGATGTGAAACTGGGGTGCTATGTTAA

>8359_8359_1_ATRX-REPS2_ATRX_chrX_76776266_ENST00000373344_REPS2_chrX_17151947_ENST00000303843_length(amino acids)=2534AA_BP=2400
MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYV
ESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHP
EPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPC
ALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLG
QENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQT
QSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
IMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTE
EKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQ
RTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG
ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTK
CPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVD
PGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQ
LDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLI
YKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVG
YHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMSEQVSEAELLPQLSRAPSQAAESSPAKKDV
LYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA

--------------------------------------------------------------
>8359_8359_2_ATRX-REPS2_ATRX_chrX_76776266_ENST00000373344_REPS2_chrX_17151947_ENST00000357277_length(transcript)=13611nt_BP=7415nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGTGAAAGCAAGTTGAATACATTGGTGCAGAAGCTTC
ATGACTTCCTTGCACACTCATCAGAAGAATCTGAAGAAACAAGTTCTCCTCCACGACTTGCAATGAATCAAAACACAGATAAAATCAGTG
GTTCTGGAAGTAACTCTGATATGATGGAAAACAGCAAGGAAGAGGGAACTAGCTCTTCAGAAAAATCCAAGTCTTCAGGATCGTCACGAT
CAAAGAGGAAACCTTCAATTGTAACAAAGTATGTAGAATCAGATGATGAAAAACCTTTGGATGATGAAACTGTAAATGAAGATGCGTCTA
ATGAAAATTCAGAAAATGATATTACTATGCAGAGCTTGCCAAAAGGTACAGTGATTGTACAGCCAGAGCCAGTGCTGAATGAAGACAAAG
ATGATTTTAAAGGGCCTGAATTTAGAAGCAGAAGTAAAATGAAAACTGAAAATCTCAAAAAACGCGGAGAAGATGGGCTTCATGGGATTG
TGAGCTGCACTGCTTGTGGACAACAGGTCAATCATTTTCAAAAAGATTCCATTTATAGACACCCTTCATTGCAAGTTCTTATTTGTAAGA
ATTGCTTTAAGTATTACATGAGTGATGATATTAGCCGTGACTCAGATGGAATGGATGAACAATGTAGGTGGTGTGCGGAAGGTGGAAACT
TGATTTGTTGTGACTTTTGCCATAATGCTTTCTGCAAGAAATGCATTCTACGCAACCTTGGTCGAAAGGAGTTGTCCACAATAATGGATG
AAAACAACCAATGGTATTGCTACATTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAACAGCGTATTTGAGAATTTAGAAC
AGTTGTTGCAGCAAAATAAGAAGAAGATAAAAGTTGACAGTGAAAAGAGTAATAAAGTATATGAACATACATCCAGATTTTCTCCAAAGA
AGACTAGTTCAAATTGTAATGGAGAAGAAAAGAAATTAGATGATTCCTGTTCTGGCTCTGTAACCTACTCTTATTCCGCACTAATTGTGC
CCAAAGAGATGATTAAGAAGGCAAAAAAACTGATTGAGACCACAGCCAACATGAACTCCAGTTATGTTAAATTTTTAAAGCAGGCAACAG
ATAATTCAGAAATCAGTTCTGCTACAAAATTACGTCAGCTTAAGGCTTTTAAGTCTGTGTTGGCTGATATTAAGAAGGCTCATCTTGCAT
TGGAAGAAGACTTAAATTCCGAGTTTCGAGCGATGGATGCTGTAAACAAAGAGAAAAATACCAAAGAGCATAAAGTCATAGATGCTAAGT
TTGAAACAAAAGCACGAAAAGGAGAAAAACCTTGTGCTTTGGAAAAGAAGGATATTTCAAAGTCAGAAGCTAAACTTTCAAGAAAACAGG
TAGATAGTGAGCACATGCATCAGAATGTTCCAACAGAGGAACAAAGAACAAATAAAAGTACCGGTGGTGAACATAAGAAATCTGATAGAA
AAGAAGAACCTCAATATGAACCTGCCAACACTTCTGAAGATTTAGACATGGATATTGTGTCTGTTCCTTCCTCAGTTCCAGAAGACATTT
TTGAGAATCTTGAGACTGCTATGGAAGTTCAGAGTTCAGTTGATCATCAAGGGGATGGCAGCAGTGGAACTGAACAAGAAGTGGAGAGTT
CATCTGTAAAATTAAATATTTCTTCAAAAGACAACAGAGGAGGTATTAAATCAAAAACTACAGCTAAAGTAACAAAAGAATTATATGTTA
AACTCACTCCTGTTTCCCTTTCTAATTCCCCAATTAAAGGTGCTGATTGTCAGGAAGTTCCACAAGATAAAGATGGCTATAAAAGTTGTG
GTCTGAACCCCAAGTTAGAGAAATGTGGACTTGGACAGGAAAACAGTGATAATGAGCATTTGGTTGAAAATGAAGTTTCATTACTTTTAG
AGGAATCTGATCTTCGAAGATCCCCACGTGTAAAGACTACACCCTTGAGGCGACCGACAGAAACTAACCCTGTAACATCTAATTCAGATG
AAGAATGTAATGAAACAGTTAAGGAGAAACAAAAACTATCAGTTCCAGTGAGAAAAAAGGATAAGCGTAATTCTTCTGACAGTGCTATAG
ATAATCCTAAGCCTAATAAATTGCCAAAATCTAAGCAATCAGAGACTGTGGATCAAAATTCAGATTCTGATGAAATGCTAGCAATCCTCA
AAGAGGTGAGCAGGATGAGTCACAGTTCTTCTTCAGATACTGATATTAATGAAATTCATACAAACCATAAGACTTTGTATGATTTAAAGA
CTCAGGCGGGGAAAGATGATAAAGGAAAAAGGAAACGAAAAAGTTCTACATCTGGCTCAGATTTTGATACTAAAAAGGGCAAATCAGCTA
AGAGCTCTATAATTTCTAAAAAGAAACGACAAACCCAGTCTGAGTCTTCTAATTATGACTCAGAATTAGAAAAAGAGATAAAGAGCATGA
GTAAAATTGGTGCTGCCAGAACCACCAAAAAAAGAATTCCAAATACAAAAGATTTTGACTCTTCTGAAGATGAGAAACACAGCAAAAAAG
GAATGGATAATCAAGGGCACAAAAATTTGAAGACCTCACAAGAAGGATCATCTGATGATGCTGAAAGAAAACAAGAGAGAGAGACTTTCT
CTTCAGCAGAAGGCACAGTTGATAAAGACACGACCATCATGGAATTAAGAGATCGACTTCCTAAGAAGCAGCAAGCAAGTGCTTCCACTG
ATGGTGTCGATAAGCTTTCTGGGAAAGAGCAGAGTTTTACTTCTTTGGAAGTTAGAAAAGTTGCTGAAACTAAAGAAAAGAGCAAGCATC
TCAAAACCAAAACATGTAAAAAAGTACAGGATGGCTTATCTGATATTGCAGAGAAATTCCTAAAGAAAGACCAGAGCGATGAAACTTCTG
AAGATGATAAAAAGCAGAGCAAAAAGGGAACTGAAGAAAAAAAGAAACCTTCAGACTTTAAGAAAAAAGTAATTAAAATGGAACAACAGT
ATGAATCTTCATCTGATGGCACTGAAAAGTTACCTGAGCGAGAAGAAATTTGTCATTTTCCTAAGGGCATAAAACAAATTAAGAATGGAA
CAACTGATGGAGAAAAGAAAAGTAAAAAAATAAGAGATAAAACTTCTAAAAAGAAGGATGAATTATCTGATTATGCTGAGAAGTCAACAG
GGAAAGGAGATAGTTGTGACTCTTCAGAGGATAAAAAGAGTAAGAATGGAGCATATGGTAGAGAGAAGAAAAGGTGCAAGTTGCTTGGAA
AGAGTTCAAGGAAGAGACAAGATTGTTCATCATCTGATACTGAGAAATATTCCATGAAAGAAGATGGTTGTAACTCTTCTGATAAGAGAC
TGAAAAGAATAGAATTGAGGGAAAGAAGAAATTTAAGTTCAAAGAGAAATACTAAGGAAATACAAAGTGGCTCATCATCATCTGATGCTG
AGGAAAGTTCTGAAGATAATAAAAAGAAGAAGCAAAGAACTTCATCTAAAAAGAAGGCAGTCATTGTCAAGGAGAAAAAGAGAAACTCCC
TAAGAACAAGCACTAAAAGGAAGCAAGCTGACATTACATCCTCATCTTCTTCTGATATAGAAGATGATGATCAGAATTCTATAGGTGAGG
GAAGCAGCGATGAACAGAAAATTAAGCCTGTGACTGAAAATTTAGTGCTGTCTTCACATACTGGATTTTGCCAATCTTCAGGAGATGAAG
CCTTATCTAAATCAGTGCCTGTCACAGTGGATGATGATGATGACGACAATGATCCTGAGAATAGAATTGCCAAGAAGATGCTTTTAGAAG
AAATTAAAGCCAATCTTTCCTCTGATGAGGATGGATCTTCAGATGATGAGCCAGAAGAAGGGAAAAAAAGAACTGGAAAACAAAATGAAG
AAAACCCAGGAGATGAGGAAGCAAAAAATCAAGTCAATTCTGAATCAGATTCAGATTCTGAAGAATCTAAGAAGCCAAGATACAGACATA
GGCTTTTGCGGCACAAATTGACTGTGAGTGACGGAGAATCTGGAGAAGAAAAAAAGACAAAGCCTAAAGAGCATAAAGAAGTCAAAGGCA
GAAACAGAAGAAAGGTGAGCAGTGAAGATTCAGAAGATTCTGATTTTCAGGAATCAGGAGTTAGTGAAGAAGTTAGTGAATCCGAAGATG
AACAGCGGCCCAGAACAAGGTCTGCAAAGAAAGCAGAGTTGGAAGAAAATCAGCGGAGCTATAAACAGAAAAAGAAAAGGCGACGTATTA
AGGTTCAAGAAGATTCATCCAGTGAAAACAAGAGTAATTCTGAGGAAGAAGAGGAGGAAAAAGAAGAGGAGGAGGAAGAGGAGGAGGAGG
AGGAAGAGGAGGAGGAAGATGAAAATGATGATTCCAAGTCTCCTGGAAAAGGCAGAAAGAAAATTCGGAAGATTCTTAAAGATGATAAAC
TGAGAACAGAAACACAAAATGCTCTTAAGGAAGAGGAAGAGAGACGAAAACGTATTGCTGAGAGGGAGCGTGAGCGAGAAAAATTGAGAG
AGGTGATAGAAATTGAAGATGCTTCACCCACCAAGTGTCCAATAACAACCAAGTTGGTTTTAGATGAAGATGAAGAAACCAAAGAACCTT
TAGTGCAGGTTCATAGAAATATGGTTATCAAATTGAAACCCCATCAAGTAGATGGTGTTCAGTTTATGTGGGATTGCTGCTGTGAGTCTG
TGAAAAAAACAAAGAAATCTCCAGGTTCAGGATGCATTCTTGCCCACTGTATGGGCCTTGGTAAGACTTTACAGGTGGTAAGTTTTCTTC
ATACAGTTCTTTTGTGTGACAAACTGGATTTCAGCACGGCGTTAGTGGTTTGTCCTCTTAATACTGCTTTGAATTGGATGAATGAATTTG
AGAAGTGGCAAGAGGGATTAAAAGATGATGAGAAGCTTGAGGTTTCTGAATTAGCAACTGTGAAACGTCCTCAGGAGAGAAGCTACATGC
TGCAGAGGTGGCAAGAAGATGGTGGTGTTATGATCATAGGCTATGAGATGTATAGAAATCTTGCTCAAGGAAGGAATGTGAAGAGTCGGA
AACTTAAAGAAATATTTAACAAAGCTTTGGTTGATCCAGGCCCTGATTTTGTTGTTTGTGATGAAGGCCATATTCTAAAAAATGAAGCAT
CTGCTGTTTCTAAAGCTATGAATTCTATACGATCAAGGAGGAGGATTATTTTAACAGGAACACCACTTCAAAATAACCTAATTGAGTATC
ATTGTATGGTTAATTTTATCAAGGAAAATTTACTTGGATCCATTAAGGAGTTCAGGAATAGATTTATAAATCCAATTCAAAATGGTCAGT
GTGCAGATTCTACCATGGTAGATGTCAGAGTGATGAAAAAACGTGCTCACATTCTCTATGAGATGTTAGCTGGATGTGTTCAGAGGAAAG
ATTATACAGCATTAACAAAATTCTTGCCTCCAAAACACGAATATGTGTTAGCTGTGAGAATGACTTCTATTCAGTGCAAGCTCTATCAGT
ACTACTTAGATCACTTAACAGGTGTGGGCAATAATAGTGAAGGTGGAAGAGGAAAGGCAGGTGCAAAGCTTTTCCAAGATTTTCAGATGT
TAAGTAGAATATGGACTCATCCTTGGTGTTTGCAGCTAGACTACATTAGCAAAGAAAATAAGGGTTATTTTGATGAAGACAGTATGGATG
AATTTATAGCCTCAGATTCTGATGAAACCTCCATGAGTTTAAGCTCCGATGATTATACAAAAAAGAAGAAAAAAGGGAAAAAGGGGAAAA
AAGATAGTAGCTCAAGTGGAAGTGGCAGTGACAATGATGTTGAAGTGATTAAGGTCTGGAATTCAAGATCTCGGGGAGGTGGTGAAGGAA
ATGTGGATGAAACAGGAAACAATCCTTCTGTTTCTTTAAAACTGGAAGAAAGTAAAGCTACTTCTTCTTCTAATCCAAGCAGCCCAGCTC
CAGACTGGTACAAAGATTTTGTTACAGATGCTGATGCTGAGGTTTTAGAGCATTCTGGGAAAATGGTACTTCTCTTTGAAATTCTTCGAA
TGGCAGAGGAAATTGGGGATAAAGTCCTTGTTTTCAGCCAGTCCCTCATATCTCTGGACTTGATTGAAGATTTTCTTGAATTAGCTAGTA
GGGAGAAGACAGAAGATAAAGATAAACCCCTTATTTATAAAGGTGAGGGGAAGTGGCTTCGAAACATTGACTATTACCGTTTAGATGGTT
CCACTACTGCACAGTCAAGGAAGAAGTGGGCTGAAGAATTTAATGATGAAACTAATGTGAGAGGACGATTATTTATCATTTCTACTAAAG
CAGGATCTCTAGGAATTAATCTGGTAGCTGCTAATCGAGTAATTATATTCGACGCTTCTTGGAATCCATCTTATGACATCCAGAGTATAT
TCAGAGTTTATCGCTTTGGACAAACTAAGCCTGTTTATGTATATAGGTTCTTAGCTCAGGGAACCATGGAAGATAAGATTTATGATCGGC
AAGTAACTAAGCAGTCACTGTCTTTTCGAGTTGTTGATCAGCAGCAGGTGGAGCGTCATTTTACTATGAATGAGCTTACTGAACTTTATA
CTTTTGAGCCAGACTTATTAGATGACCCTAATTCAGAAAAGAAGAAGAAGAGGGATACTCCCATGCTGCCAAAGGATACCATACTTGCAG
AGCTCCTTCAGATACATAAAGAACACATTGTAGGATACCATGAACATGATTCTCTTTTGGACCACAAAGAAGAAGAAGAGTTGACTGAAG
AAGAAAGAAAAGCAGCTTGGGCTGAGTATGAAGCAGAGAAGAAGGGACTGACCATGCGTTTCAACATACCAACTGGGACCAATTTACCCC
CTGTCAGTTTCAACTCTCAAACTCCTTATATTCCTTTCAATTTGGGAGCCCTGTCAGCAATGAGTAATCAACAGCTGGAGGACCTCATTA
ATCAAGGAAGAGAAAAAGTTGTAGAAGCAACAAACAGTGTGACAGCAGTGAGGATTCAACCTCTTGAGGATATAATTTCAGCTGTATGGA
AGGAGAACATGAATCTCTCAGAGGCCCAAGTACAGGCGTTAGCATTAAGTAGACAAGCCAGCCAGGAGCTTGATGTTAAACGAAGAGAAG
CAATCTACAATGATGTATTGACAAAACAACAGATGTCTGAACAAGTGTCGGAGGCCGAGTTACTCCCACAGCTGAGCAGAGCCCCATCCC
AGGCTGCAGAAAGTAGTCCAGCAAAGAAGGATGTACTGTATTCTCAGCCACCATCAAAGCCCATTCGTAGGAAATTCAGACCAGAAAACC
AAGCTACAGAAAACCAAGAGCCTTCCACTGCTGCAAGTGGGCCAGCTTCTGCGGCAACCATGAAACCGCATCCAACAGTCCAAAAGCAGT
CTTCCAAACAGAAGAAGGCCATTCAAACTGCTATCCGCAAAAATAAAGAGGCAAACGCAGTGCTGGCTCGGCTGAACAGTGAGCTCCAGC
AGCAGCTCAAGGAGGTTCATCAAGAACGAATTGCATTGGAAAACCAATTGGAACAACTTCGTCCGGTCACTGTGTTGTGACCCCCCCATG
GTTCAAGTGACAGTGGGTGACCTTGTCTGCCAAGATCTTTCTTTTGAATGTTTTGAACCCAACTACTTGTCATAGATGTTTGACTGTGTC
AAAAGCTGTGAGCAGCAAAATATAATCCATATGACCTTTTCTCTTGCACTTCACTTGTATGTTTTACTGTGGTGGAAAAAATACTTCAAC
TGATTATCACACTTGAAATGCTAATTATCAGTGGAATTTGTCTCCTATTCTTAAGTACTTCTGCAAGGTATTAGATGCTGCTCCTTACCA
AAAATCAGTCTTCTAGCAAATAAAAATAACTTAGAGCATTATTTATTTAAAGAATTTATGTTTTCTATAAAACCTTATAACCAAGAACCT
TCAGGATGCTTGTAACCAAGTACTTTCAGGATGCTTTTTGTATGTATATCACATAGAGTAGGTTGGTTTCCTGAGTAATTGGGATTCCAA
CTAGATAGTCATTGGTGTGACCATAATAAAAACAAAAGCTAAAATAAAAGCATCAGATTTAGACTGGCGCTGTGCCCTCTACCACTATAT
GCCAAAAATTGCTTCTCTAGTGCCATTTTGATATTATATCTAGCTATAAATAATACATGACTATCGTTTTCTATTGAATGTCAAAGACTT
ACTGGGTCTTTACACCTCTGTAAAGTGGAGGTTTTGGCAATGAGCTGTTTAACTTGGCCAAGCTAGGCTGTCAACCCAGACAACTCAGTC
CTTTCATGTAAATTTTTGGGCAAGAGAAGTCTGCTTTGACTGCCTTGCCTGACCAAATTAAATAAATAGTTGCCAGATCTCTACTTTTAT
CCTGCATGGGATAATATATCTGTAAATGCATGAGTTTGGAAACCACCCATCAAATATGAAAGGCTGATGAGACTGTTAGGATTGATAAAC
ATTTGTTGTTTGAACCCAGCTATCCAAACTGGGGAAGAAGGGGAAATGGTTGTTACCAACAATCTCTAGTAGTTATTTTAATCTTTATTT
TAACCTGGATTGCAAATGTATGGGGTATGAGGAGATAATGAAAGAAAAGTGGTCCTCATGCTGGATATGTGACTGTTTTGTTCTCTGTAA
AGTGTATTCTTGGGAAGTGATTGGTTTATATCAGATTCAGAGGAGCCCAATTAACTCCAGTGTAGGTAATGTAAAACAGTAAGCTCAAAT
TGCAGAAGCCAGTATCCTACAGAAATTTAAGTAGCTACTGCTTCTCCTGAAAGCCCAAGTTGAAAATGGGACCACAGGGGCACAGGGCTA
CTGACCCTCACAGGGCATGCCAGCGTTAACACCACTTTGAGAGACCAATGGCAAGAAATGCTGTCTCTTGTGCATTTTACTAATTTCCCC
ATTCTTAGGGTAGCAGGGTGGGGGTGTATAGGGTCTTTTTGAAGCAGTTTTGGATAGGTTTGCAATATGTGGGATTCAGCCTTTGATTTC
AATAGAGCTGAGAGCTTTTAGAACAAGCAGGCATTTATTTAATGTTTCCTTAGTCCATTGGCAAGCTTTATCAATAGCTTAATGGCAGAG
GATAAAGGCTCAAACAGATGATGTTTTTTCCACAGAAAAACAAATTGTTGAATCTATTCCGTGCATATTTAAGGATTTTGAATTGATTTT
GAAAATCATGAAACTTGAACTATTTTTCTATTCCCTTTTTTTCTTCCCCATTTGCTGCCTTTTTTGTTTTTGTGGGGGAAGGGTTGGGAG
TAAGTTTAAACTCTTCCGAAGATTATGAATGGGTCAGCACAAATTTTTAGGCAACTGCTTTTTCCATGTTCTGAGATCTACGGGCTACAA
CAAATTTTATCAGCAGTGTTTTTTGTTTTTTTGAGATGGAGACTTGCTCTGTCGCCCAGGCTGGAGCGCAGTGGCGCAATCTCGGCTCAC
TGCAACCTCCACCTCCTGGGTTCAAGCAATTCTTGTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCCACCACCACGCTCAGCTA
ATTTTTGTATTTTTAGTAGAGATGGGATTTTGTCATGTTGGCTAGGCTAGTCTCGAATTCCTGACCTCAAGTGATCCACCCGCCTTGGCC
TCTCGAAGTGCTGGGATTACAGGCGTGAGCCACCCGCCCGGCTATCAGCACTGTTCTGATTGCAGACGTTTCACAGCATGTTTGGCTTTT
GGTAAATTCAATCCAGGAAAGACTAGCATGTGCACTTTATCTCATAATCTTCCAGTACATATGCTCTCAGTTGGGATAGCAGTTCATTTC
CATTAGGCAGACGTATAAACTAAGGAATGTTAGTCTGCAGTATTCATTTTAAAAATATTGACATGCTTTTCCCCTCCCCTCCATGAAGTC
AGTGCCAGAGTGAGCCAGATTGGGAGGTTGGGGTTTTGTTTGGTTGGCTTGGTTTTCATTAAGGGAAAAAACTTGCATTGGACAATCAAA
TTCCCCTGAGTTTCATAATCTCATCAATATTTTAAGATAGGCGAGCACACACTAATAATATCTATGCCTACCTTCTTGGGTGGACTCAAC
TGTAACCACAGTTTATTAGTTGCTTAGAAGTGGATTTTTAAAAAACAGTTAAATGTGTGTGCATAACACACAAGTAATGACACACTACTA
TTATTATTACCTAAGTAGTGCTCATCCTCTCTTTCTGTGTTTTCTTAGGATGTGCACTTTAATTTAGGATTGTAACGCCTAATAATATTT
CTGTGAGCCTTTAATGTGATTTATAAGATGGCCGAATTACTGAAATCACCATTATACCTCTTCCATAAAACGACTCCAAAGTTAGACCTG
CCTGTTGGGGAGAATTCTATAGACAGAAGGTCAATGTTGTCCCCATCCATAGGGGTTGAATTACCTTGCTGTTAAGTGGTCTTCCCCCAT
TGGGATCCTACAGTCCCACAGATGAAAGCACAGTAGTAGCTGACAGCTGGCTTATTTGGTCCCTCGGCATCTCTCGTATGTGGCATATTG
CTTTTGCCACTTTCCTATCCAGCAGACATCAAAGCAAAACTAAAAGGTAGATATCTGGAATGAATGTATATGTTGTAATTGAGGCAGATA
TTTGCCTTAATTGGAAGGATCTAACTGCTTTACAAATATTAAACAAGTGCTTGGGCATGATTGGGAGAGGAGGCAGCTTAGCTGGAAGCT
GTGCCCATCTTACTGTCACTGGAGAATAGGATGTCAGAGCTGGGCAGGACTGGTACCCATCATTTGCAGTTTGCATGTGGGGAAACCAAA
GCCCTAAGAAACAACAGTTCCTGGCCCAAAAAATCCATAGAAAGAGGTAACTAGTGGCAGATTTGGGGCGCCAACCTGATTTTATGGATT
TTGAGTTAGATTCTCTACCCTCTATCAATACTAAAAATAGATTAGGAGGGTTTTTTTTTCTGTTTATCATGTTGAATTTCATTGACTTAA
TTAGTCTTTAAATTTGAAAACATGTTTTAGGGAGTTTAGTTCTAGAAATTTCTCTTAGATTGAAGTGACAGAATCTGAAAGAAAAGAATA
TGATTGAGCTATTTGTTTTCCTGAACACCTCACCTTTTATGATGCAATAAGTTACTCTGAGTTTCTTGGCAGAGTTTTTGACAGCTGTTG
CTTTCAATGGATTCCATTCCTGTATTCCTTATGGGAGGTTGTTTTTAAAATAGACTACTGCGATTGAAATGAACTCAATATGTAGTTAAG
TTATAGTTTTCTTCAATGTATTTTTAGTTACTTGGGTCACAAATGTTCAATTTCAGCATATTTTAGGGTGAGTAATCAAAAATGTGAATT
TGCCTTTGATTTCCTACCACTGTCTGAGCTATCATAAAGCATTCTCTTTAGTTGTGATTTGATTCTATAGTCTGTTTCTAAATGACATTT
GTCTGTTTCTTAAATGATCTCACAGCCATGGTAATAATAGATGTGTACTCAGAAGATCAATAAGGTAATATTGGAATTCATGTGTTTTTT
GCAATTAAGGCAGGCATTTGCCAATGTCTTCTTTTAAGCAGTAGTTGGAAACATCTCAATTACAGTGTAACACCTTAGAGCTAAAAACAT
TTGTTCAACACAAACTAGAATCACACCTTCTCACTAGATATCACCAAGGGAATGTGGTTTTAAAAATAAAAAGAAAACAATATAACGTAT
CATGGCAACCAGAGCTTCCCATATTATTGACAAGTAGGGATCATTAGGTTCTGGTTTGAACATTCTGAATGTGAACAAAATGAAATAGTA
GTTAAGAGGTGTTTTCCCACTGTGTTTAAAGAGAACACTAGTAATTCTGGTTTTTCTTTCTAACTGCTTTACTGTTTCAAGGGTATTCTT
TTAAAACTCTGATTTCAAAGGATCAGTTGAATTTATACTTTAGTTATGGGTGTTTTGTTACTTTTTTTTTTTTTGTATCATGACTCAGTA
TGGTTCAATTTCCTAGTAAGAAGTGGGGATTTGTGTTTTTGGAGTCCTCAGCTCACATGTCTTGTTCCTCCTTCAGCACAAGCTAGGGGA
GATCCTACCAACACTGATAGGTCAGTCATTGATGGCAATTTGAATGTGGGTATTACTCTGTGAGCCACCCTGCTTCGCTTGTTTGTAAGG
AGAAATGCATCTGGTTATGTGAATTTCCCGAGAGCAGCAGACATGGAGGGCCAGACTTTAAAAGCAACGCAAGCAGATTCGAAGAGCTGT
TGCCCTCTTCTAAAAAAGGCTTTTGGAGGCTGTGTTACATGCATGCCCTAAAGCAGTCAGTCTGTTAGTATGAGCAAGACATCTGAAGTA
CACAGTTGCTTTTAGGCTTGTATAGTTATTTTCTACACATGCCAACACACATGATGATAAAGGAACCTTTTCTAGGAGGCATTGCAGGGT
TTCAATACACAGGACATGTTCTAGTTACAGAAGCCTTGCTCTGCTGTCAACAATTGGGAAATGCTCATTTTTTCATGTTTTGTGAATACT
CTGGTCTTGCTGTAAGCTAATGTCATGGCTGTGGGATATTAGAGAAGTGGGTTTATGACTCTGAAGACCAGCAGACACCAGACTTTAAAA
GTGCTTAAATTGGAATTTGGAAACTACAGTAAAGAAACCTTCAGATACCAGTTCCATCCTGAAGCCCTCTGTTGAACAACAGGGCCAGAT
CCTAAAGCTCTTTCAGGGAGCTCTTCTCTGGGGCTGGAACAGTTGATTATGCAACCCCATTGTGTGGAGATTGGATCAACTGAGTTGTGT
TATTTTTGTTTTAAGTCACCTTGTGCGAGAACCTCAACCGCACCTATCTTGGGAACCGGGTATACCCTTTTCTTTAGCACTGCTATCCTT
TTTGTCTTCAGCACAAATAAGATGTTCAAGTGAGCCAGAAGCAAGAAGAGCCATTTTAGTCTTCATAGCTATTGGCTAAGAGAGATAATG
AGCTGATGGTCTATTTTAACCTTGAAAGTAAAAATGTATATTTTTTCACTACAAGTACATTGAACAGTAAAAAGTGTAACAGCAAAGTAT
ATATTTGATGCCTTCTGTCTTTTCATGATAATGTGCTAACAAGTTGTGTTAATATTTTACTCAGCCAGAGTCTCATTCATTTGCTAAGCA
TTGGGAACATTATGTATATTGACCTTAAACATAGGTGTCCTATATTTGGATTGTGACTTGTAGACTCAAGCTAACCTTACTGCCTCTTTT
TCACACTTGTTGAAAAGTCTGTGAAGAACATAGTTAAAGATCTCCAACTTTGGAAAATATACATGATGTGAAACTGGGGTGCTATGTTAA

>8359_8359_2_ATRX-REPS2_ATRX_chrX_76776266_ENST00000373344_REPS2_chrX_17151947_ENST00000357277_length(amino acids)=2534AA_BP=2400
MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYV
ESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHP
EPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPC
ALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLG
QENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQT
QSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
IMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTE
EKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQ
RTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG
ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTK
CPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVD
PGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQ
LDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLI
YKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVG
YHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMSEQVSEAELLPQLSRAPSQAAESSPAKKDV
LYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA

--------------------------------------------------------------
>8359_8359_3_ATRX-REPS2_ATRX_chrX_76776266_ENST00000373344_REPS2_chrX_17151947_ENST00000380064_length(transcript)=7961nt_BP=7415nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGTGAAAGCAAGTTGAATACATTGGTGCAGAAGCTTC
ATGACTTCCTTGCACACTCATCAGAAGAATCTGAAGAAACAAGTTCTCCTCCACGACTTGCAATGAATCAAAACACAGATAAAATCAGTG
GTTCTGGAAGTAACTCTGATATGATGGAAAACAGCAAGGAAGAGGGAACTAGCTCTTCAGAAAAATCCAAGTCTTCAGGATCGTCACGAT
CAAAGAGGAAACCTTCAATTGTAACAAAGTATGTAGAATCAGATGATGAAAAACCTTTGGATGATGAAACTGTAAATGAAGATGCGTCTA
ATGAAAATTCAGAAAATGATATTACTATGCAGAGCTTGCCAAAAGGTACAGTGATTGTACAGCCAGAGCCAGTGCTGAATGAAGACAAAG
ATGATTTTAAAGGGCCTGAATTTAGAAGCAGAAGTAAAATGAAAACTGAAAATCTCAAAAAACGCGGAGAAGATGGGCTTCATGGGATTG
TGAGCTGCACTGCTTGTGGACAACAGGTCAATCATTTTCAAAAAGATTCCATTTATAGACACCCTTCATTGCAAGTTCTTATTTGTAAGA
ATTGCTTTAAGTATTACATGAGTGATGATATTAGCCGTGACTCAGATGGAATGGATGAACAATGTAGGTGGTGTGCGGAAGGTGGAAACT
TGATTTGTTGTGACTTTTGCCATAATGCTTTCTGCAAGAAATGCATTCTACGCAACCTTGGTCGAAAGGAGTTGTCCACAATAATGGATG
AAAACAACCAATGGTATTGCTACATTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAACAGCGTATTTGAGAATTTAGAAC
AGTTGTTGCAGCAAAATAAGAAGAAGATAAAAGTTGACAGTGAAAAGAGTAATAAAGTATATGAACATACATCCAGATTTTCTCCAAAGA
AGACTAGTTCAAATTGTAATGGAGAAGAAAAGAAATTAGATGATTCCTGTTCTGGCTCTGTAACCTACTCTTATTCCGCACTAATTGTGC
CCAAAGAGATGATTAAGAAGGCAAAAAAACTGATTGAGACCACAGCCAACATGAACTCCAGTTATGTTAAATTTTTAAAGCAGGCAACAG
ATAATTCAGAAATCAGTTCTGCTACAAAATTACGTCAGCTTAAGGCTTTTAAGTCTGTGTTGGCTGATATTAAGAAGGCTCATCTTGCAT
TGGAAGAAGACTTAAATTCCGAGTTTCGAGCGATGGATGCTGTAAACAAAGAGAAAAATACCAAAGAGCATAAAGTCATAGATGCTAAGT
TTGAAACAAAAGCACGAAAAGGAGAAAAACCTTGTGCTTTGGAAAAGAAGGATATTTCAAAGTCAGAAGCTAAACTTTCAAGAAAACAGG
TAGATAGTGAGCACATGCATCAGAATGTTCCAACAGAGGAACAAAGAACAAATAAAAGTACCGGTGGTGAACATAAGAAATCTGATAGAA
AAGAAGAACCTCAATATGAACCTGCCAACACTTCTGAAGATTTAGACATGGATATTGTGTCTGTTCCTTCCTCAGTTCCAGAAGACATTT
TTGAGAATCTTGAGACTGCTATGGAAGTTCAGAGTTCAGTTGATCATCAAGGGGATGGCAGCAGTGGAACTGAACAAGAAGTGGAGAGTT
CATCTGTAAAATTAAATATTTCTTCAAAAGACAACAGAGGAGGTATTAAATCAAAAACTACAGCTAAAGTAACAAAAGAATTATATGTTA
AACTCACTCCTGTTTCCCTTTCTAATTCCCCAATTAAAGGTGCTGATTGTCAGGAAGTTCCACAAGATAAAGATGGCTATAAAAGTTGTG
GTCTGAACCCCAAGTTAGAGAAATGTGGACTTGGACAGGAAAACAGTGATAATGAGCATTTGGTTGAAAATGAAGTTTCATTACTTTTAG
AGGAATCTGATCTTCGAAGATCCCCACGTGTAAAGACTACACCCTTGAGGCGACCGACAGAAACTAACCCTGTAACATCTAATTCAGATG
AAGAATGTAATGAAACAGTTAAGGAGAAACAAAAACTATCAGTTCCAGTGAGAAAAAAGGATAAGCGTAATTCTTCTGACAGTGCTATAG
ATAATCCTAAGCCTAATAAATTGCCAAAATCTAAGCAATCAGAGACTGTGGATCAAAATTCAGATTCTGATGAAATGCTAGCAATCCTCA
AAGAGGTGAGCAGGATGAGTCACAGTTCTTCTTCAGATACTGATATTAATGAAATTCATACAAACCATAAGACTTTGTATGATTTAAAGA
CTCAGGCGGGGAAAGATGATAAAGGAAAAAGGAAACGAAAAAGTTCTACATCTGGCTCAGATTTTGATACTAAAAAGGGCAAATCAGCTA
AGAGCTCTATAATTTCTAAAAAGAAACGACAAACCCAGTCTGAGTCTTCTAATTATGACTCAGAATTAGAAAAAGAGATAAAGAGCATGA
GTAAAATTGGTGCTGCCAGAACCACCAAAAAAAGAATTCCAAATACAAAAGATTTTGACTCTTCTGAAGATGAGAAACACAGCAAAAAAG
GAATGGATAATCAAGGGCACAAAAATTTGAAGACCTCACAAGAAGGATCATCTGATGATGCTGAAAGAAAACAAGAGAGAGAGACTTTCT
CTTCAGCAGAAGGCACAGTTGATAAAGACACGACCATCATGGAATTAAGAGATCGACTTCCTAAGAAGCAGCAAGCAAGTGCTTCCACTG
ATGGTGTCGATAAGCTTTCTGGGAAAGAGCAGAGTTTTACTTCTTTGGAAGTTAGAAAAGTTGCTGAAACTAAAGAAAAGAGCAAGCATC
TCAAAACCAAAACATGTAAAAAAGTACAGGATGGCTTATCTGATATTGCAGAGAAATTCCTAAAGAAAGACCAGAGCGATGAAACTTCTG
AAGATGATAAAAAGCAGAGCAAAAAGGGAACTGAAGAAAAAAAGAAACCTTCAGACTTTAAGAAAAAAGTAATTAAAATGGAACAACAGT
ATGAATCTTCATCTGATGGCACTGAAAAGTTACCTGAGCGAGAAGAAATTTGTCATTTTCCTAAGGGCATAAAACAAATTAAGAATGGAA
CAACTGATGGAGAAAAGAAAAGTAAAAAAATAAGAGATAAAACTTCTAAAAAGAAGGATGAATTATCTGATTATGCTGAGAAGTCAACAG
GGAAAGGAGATAGTTGTGACTCTTCAGAGGATAAAAAGAGTAAGAATGGAGCATATGGTAGAGAGAAGAAAAGGTGCAAGTTGCTTGGAA
AGAGTTCAAGGAAGAGACAAGATTGTTCATCATCTGATACTGAGAAATATTCCATGAAAGAAGATGGTTGTAACTCTTCTGATAAGAGAC
TGAAAAGAATAGAATTGAGGGAAAGAAGAAATTTAAGTTCAAAGAGAAATACTAAGGAAATACAAAGTGGCTCATCATCATCTGATGCTG
AGGAAAGTTCTGAAGATAATAAAAAGAAGAAGCAAAGAACTTCATCTAAAAAGAAGGCAGTCATTGTCAAGGAGAAAAAGAGAAACTCCC
TAAGAACAAGCACTAAAAGGAAGCAAGCTGACATTACATCCTCATCTTCTTCTGATATAGAAGATGATGATCAGAATTCTATAGGTGAGG
GAAGCAGCGATGAACAGAAAATTAAGCCTGTGACTGAAAATTTAGTGCTGTCTTCACATACTGGATTTTGCCAATCTTCAGGAGATGAAG
CCTTATCTAAATCAGTGCCTGTCACAGTGGATGATGATGATGACGACAATGATCCTGAGAATAGAATTGCCAAGAAGATGCTTTTAGAAG
AAATTAAAGCCAATCTTTCCTCTGATGAGGATGGATCTTCAGATGATGAGCCAGAAGAAGGGAAAAAAAGAACTGGAAAACAAAATGAAG
AAAACCCAGGAGATGAGGAAGCAAAAAATCAAGTCAATTCTGAATCAGATTCAGATTCTGAAGAATCTAAGAAGCCAAGATACAGACATA
GGCTTTTGCGGCACAAATTGACTGTGAGTGACGGAGAATCTGGAGAAGAAAAAAAGACAAAGCCTAAAGAGCATAAAGAAGTCAAAGGCA
GAAACAGAAGAAAGGTGAGCAGTGAAGATTCAGAAGATTCTGATTTTCAGGAATCAGGAGTTAGTGAAGAAGTTAGTGAATCCGAAGATG
AACAGCGGCCCAGAACAAGGTCTGCAAAGAAAGCAGAGTTGGAAGAAAATCAGCGGAGCTATAAACAGAAAAAGAAAAGGCGACGTATTA
AGGTTCAAGAAGATTCATCCAGTGAAAACAAGAGTAATTCTGAGGAAGAAGAGGAGGAAAAAGAAGAGGAGGAGGAAGAGGAGGAGGAGG
AGGAAGAGGAGGAGGAAGATGAAAATGATGATTCCAAGTCTCCTGGAAAAGGCAGAAAGAAAATTCGGAAGATTCTTAAAGATGATAAAC
TGAGAACAGAAACACAAAATGCTCTTAAGGAAGAGGAAGAGAGACGAAAACGTATTGCTGAGAGGGAGCGTGAGCGAGAAAAATTGAGAG
AGGTGATAGAAATTGAAGATGCTTCACCCACCAAGTGTCCAATAACAACCAAGTTGGTTTTAGATGAAGATGAAGAAACCAAAGAACCTT
TAGTGCAGGTTCATAGAAATATGGTTATCAAATTGAAACCCCATCAAGTAGATGGTGTTCAGTTTATGTGGGATTGCTGCTGTGAGTCTG
TGAAAAAAACAAAGAAATCTCCAGGTTCAGGATGCATTCTTGCCCACTGTATGGGCCTTGGTAAGACTTTACAGGTGGTAAGTTTTCTTC
ATACAGTTCTTTTGTGTGACAAACTGGATTTCAGCACGGCGTTAGTGGTTTGTCCTCTTAATACTGCTTTGAATTGGATGAATGAATTTG
AGAAGTGGCAAGAGGGATTAAAAGATGATGAGAAGCTTGAGGTTTCTGAATTAGCAACTGTGAAACGTCCTCAGGAGAGAAGCTACATGC
TGCAGAGGTGGCAAGAAGATGGTGGTGTTATGATCATAGGCTATGAGATGTATAGAAATCTTGCTCAAGGAAGGAATGTGAAGAGTCGGA
AACTTAAAGAAATATTTAACAAAGCTTTGGTTGATCCAGGCCCTGATTTTGTTGTTTGTGATGAAGGCCATATTCTAAAAAATGAAGCAT
CTGCTGTTTCTAAAGCTATGAATTCTATACGATCAAGGAGGAGGATTATTTTAACAGGAACACCACTTCAAAATAACCTAATTGAGTATC
ATTGTATGGTTAATTTTATCAAGGAAAATTTACTTGGATCCATTAAGGAGTTCAGGAATAGATTTATAAATCCAATTCAAAATGGTCAGT
GTGCAGATTCTACCATGGTAGATGTCAGAGTGATGAAAAAACGTGCTCACATTCTCTATGAGATGTTAGCTGGATGTGTTCAGAGGAAAG
ATTATACAGCATTAACAAAATTCTTGCCTCCAAAACACGAATATGTGTTAGCTGTGAGAATGACTTCTATTCAGTGCAAGCTCTATCAGT
ACTACTTAGATCACTTAACAGGTGTGGGCAATAATAGTGAAGGTGGAAGAGGAAAGGCAGGTGCAAAGCTTTTCCAAGATTTTCAGATGT
TAAGTAGAATATGGACTCATCCTTGGTGTTTGCAGCTAGACTACATTAGCAAAGAAAATAAGGGTTATTTTGATGAAGACAGTATGGATG
AATTTATAGCCTCAGATTCTGATGAAACCTCCATGAGTTTAAGCTCCGATGATTATACAAAAAAGAAGAAAAAAGGGAAAAAGGGGAAAA
AAGATAGTAGCTCAAGTGGAAGTGGCAGTGACAATGATGTTGAAGTGATTAAGGTCTGGAATTCAAGATCTCGGGGAGGTGGTGAAGGAA
ATGTGGATGAAACAGGAAACAATCCTTCTGTTTCTTTAAAACTGGAAGAAAGTAAAGCTACTTCTTCTTCTAATCCAAGCAGCCCAGCTC
CAGACTGGTACAAAGATTTTGTTACAGATGCTGATGCTGAGGTTTTAGAGCATTCTGGGAAAATGGTACTTCTCTTTGAAATTCTTCGAA
TGGCAGAGGAAATTGGGGATAAAGTCCTTGTTTTCAGCCAGTCCCTCATATCTCTGGACTTGATTGAAGATTTTCTTGAATTAGCTAGTA
GGGAGAAGACAGAAGATAAAGATAAACCCCTTATTTATAAAGGTGAGGGGAAGTGGCTTCGAAACATTGACTATTACCGTTTAGATGGTT
CCACTACTGCACAGTCAAGGAAGAAGTGGGCTGAAGAATTTAATGATGAAACTAATGTGAGAGGACGATTATTTATCATTTCTACTAAAG
CAGGATCTCTAGGAATTAATCTGGTAGCTGCTAATCGAGTAATTATATTCGACGCTTCTTGGAATCCATCTTATGACATCCAGAGTATAT
TCAGAGTTTATCGCTTTGGACAAACTAAGCCTGTTTATGTATATAGGTTCTTAGCTCAGGGAACCATGGAAGATAAGATTTATGATCGGC
AAGTAACTAAGCAGTCACTGTCTTTTCGAGTTGTTGATCAGCAGCAGGTGGAGCGTCATTTTACTATGAATGAGCTTACTGAACTTTATA
CTTTTGAGCCAGACTTATTAGATGACCCTAATTCAGAAAAGAAGAAGAAGAGGGATACTCCCATGCTGCCAAAGGATACCATACTTGCAG
AGCTCCTTCAGATACATAAAGAACACATTGTAGGATACCATGAACATGATTCTCTTTTGGACCACAAAGAAGAAGAAGAGTTGACTGAAG
AAGAAAGAAAAGCAGCTTGGGCTGAGTATGAAGCAGAGAAGAAGGGACTGACCATGCGTTTCAACATACCAACTGGGACCAATTTACCCC
CTGTCAGTTTCAACTCTCAAACTCCTTATATTCCTTTCAATTTGGGAGCCCTGTCAGCAATGAGTAATCAACAGCTGGAGGACCTCATTA
ATCAAGGAAGAGAAAAAGTTGTAGAAGCAACAAACAGTGTGACAGCAGTGAGGATTCAACCTCTTGAGGATATAATTTCAGCTGTATGGA
AGGAGAACATGAATCTCTCAGAGGCCCAAGTACAGGCGTTAGCATTAAGTAGACAAGCCAGCCAGGAGCTTGATGTTAAACGAAGAGAAG
CAATCTACAATGATGTATTGACAAAACAACAGATGTCTGAACAAGTGTCGGAGGCCGAGTTACTCCCACAGCTGAGCAGAGCCCCATCCC
AGGCTGCAGAAAGTAGTCCAGCAAAGAAGGATGTACTGTATTCTCAGCCACCATCAAAGCCCATTCGTAGGAAATTCAGACCAGAAAACC
AAGCTACAGAAAACCAAGAGCCTTCCACTGCTGCAAGTGGGCCAGCTTCTGCGGCAACCATGAAACCGCATCCAACAGTCCAAAAGCAGT
CTTCCAAACAGAAGAAGGCCATTCAAACTGCTATCCGCAAAAATAAAGAGGCAAACGCAGTGCTGGCTCGGCTGAACAGTGAGCTCCAGC
AGCAGCTCAAGGAGGTTCATCAAGAACGAATTGCATTGGAAAACCAATTGGAACAACTTCGTCCGGTCACTGTGTTGTGACCCCCCCATG
GTTCAAGTGACAGTGGGTGACCTTGTCTGCCAAGATCTTTCTTTTGAATGTTTTGAACCCAACTACTTGTCATAGATGTTTGACTGTGTC

>8359_8359_3_ATRX-REPS2_ATRX_chrX_76776266_ENST00000373344_REPS2_chrX_17151947_ENST00000380064_length(amino acids)=2534AA_BP=2400
MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYV
ESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHP
EPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPC
ALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLG
QENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQT
QSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
IMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTE
EKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQ
RTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG
ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTK
CPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVD
PGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQ
LDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLI
YKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVG
YHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMSEQVSEAELLPQLSRAPSQAAESSPAKKDV
LYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA

--------------------------------------------------------------
>8359_8359_4_ATRX-REPS2_ATRX_chrX_76776266_ENST00000395603_REPS2_chrX_17151947_ENST00000303843_length(transcript)=13497nt_BP=7301nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGTGAAAGCAAGTTGAATACATTGGTGCAGAAGCTTC
ATGACTTCCTTGCACACTCATCAGAAGAATCTGAAGAAACAAGTTCTCCTCCACGACTTGCAATGAATCAAAACACAGATAAAATCAGTG
GTTCTGGAAGTAACTCTGATATGATGGAAAACAGCAAGGAAGAGGGAACTAGCTCTTCAGAAAAATCCAAGTCTTCAGGATCGTCACGAT
CAAAGAGGAAACCTTCAATTGTAACAAAGTATGTAGAATCAGATGATGAAAAACCTTTGGATGATGAAACTGTAAATGAAGATGCGTCTA
ATGAAAATTCAGAAAATGATATTACTATGCAGAGCTTGCCAAAAGAAGATGGGCTTCATGGGATTGTGAGCTGCACTGCTTGTGGACAAC
AGGTCAATCATTTTCAAAAAGATTCCATTTATAGACACCCTTCATTGCAAGTTCTTATTTGTAAGAATTGCTTTAAGTATTACATGAGTG
ATGATATTAGCCGTGACTCAGATGGAATGGATGAACAATGTAGGTGGTGTGCGGAAGGTGGAAACTTGATTTGTTGTGACTTTTGCCATA
ATGCTTTCTGCAAGAAATGCATTCTACGCAACCTTGGTCGAAAGGAGTTGTCCACAATAATGGATGAAAACAACCAATGGTATTGCTACA
TTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAACAGCGTATTTGAGAATTTAGAACAGTTGTTGCAGCAAAATAAGAAGA
AGATAAAAGTTGACAGTGAAAAGAGTAATAAAGTATATGAACATACATCCAGATTTTCTCCAAAGAAGACTAGTTCAAATTGTAATGGAG
AAGAAAAGAAATTAGATGATTCCTGTTCTGGCTCTGTAACCTACTCTTATTCCGCACTAATTGTGCCCAAAGAGATGATTAAGAAGGCAA
AAAAACTGATTGAGACCACAGCCAACATGAACTCCAGTTATGTTAAATTTTTAAAGCAGGCAACAGATAATTCAGAAATCAGTTCTGCTA
CAAAATTACGTCAGCTTAAGGCTTTTAAGTCTGTGTTGGCTGATATTAAGAAGGCTCATCTTGCATTGGAAGAAGACTTAAATTCCGAGT
TTCGAGCGATGGATGCTGTAAACAAAGAGAAAAATACCAAAGAGCATAAAGTCATAGATGCTAAGTTTGAAACAAAAGCACGAAAAGGAG
AAAAACCTTGTGCTTTGGAAAAGAAGGATATTTCAAAGTCAGAAGCTAAACTTTCAAGAAAACAGGTAGATAGTGAGCACATGCATCAGA
ATGTTCCAACAGAGGAACAAAGAACAAATAAAAGTACCGGTGGTGAACATAAGAAATCTGATAGAAAAGAAGAACCTCAATATGAACCTG
CCAACACTTCTGAAGATTTAGACATGGATATTGTGTCTGTTCCTTCCTCAGTTCCAGAAGACATTTTTGAGAATCTTGAGACTGCTATGG
AAGTTCAGAGTTCAGTTGATCATCAAGGGGATGGCAGCAGTGGAACTGAACAAGAAGTGGAGAGTTCATCTGTAAAATTAAATATTTCTT
CAAAAGACAACAGAGGAGGTATTAAATCAAAAACTACAGCTAAAGTAACAAAAGAATTATATGTTAAACTCACTCCTGTTTCCCTTTCTA
ATTCCCCAATTAAAGGTGCTGATTGTCAGGAAGTTCCACAAGATAAAGATGGCTATAAAAGTTGTGGTCTGAACCCCAAGTTAGAGAAAT
GTGGACTTGGACAGGAAAACAGTGATAATGAGCATTTGGTTGAAAATGAAGTTTCATTACTTTTAGAGGAATCTGATCTTCGAAGATCCC
CACGTGTAAAGACTACACCCTTGAGGCGACCGACAGAAACTAACCCTGTAACATCTAATTCAGATGAAGAATGTAATGAAACAGTTAAGG
AGAAACAAAAACTATCAGTTCCAGTGAGAAAAAAGGATAAGCGTAATTCTTCTGACAGTGCTATAGATAATCCTAAGCCTAATAAATTGC
CAAAATCTAAGCAATCAGAGACTGTGGATCAAAATTCAGATTCTGATGAAATGCTAGCAATCCTCAAAGAGGTGAGCAGGATGAGTCACA
GTTCTTCTTCAGATACTGATATTAATGAAATTCATACAAACCATAAGACTTTGTATGATTTAAAGACTCAGGCGGGGAAAGATGATAAAG
GAAAAAGGAAACGAAAAAGTTCTACATCTGGCTCAGATTTTGATACTAAAAAGGGCAAATCAGCTAAGAGCTCTATAATTTCTAAAAAGA
AACGACAAACCCAGTCTGAGTCTTCTAATTATGACTCAGAATTAGAAAAAGAGATAAAGAGCATGAGTAAAATTGGTGCTGCCAGAACCA
CCAAAAAAAGAATTCCAAATACAAAAGATTTTGACTCTTCTGAAGATGAGAAACACAGCAAAAAAGGAATGGATAATCAAGGGCACAAAA
ATTTGAAGACCTCACAAGAAGGATCATCTGATGATGCTGAAAGAAAACAAGAGAGAGAGACTTTCTCTTCAGCAGAAGGCACAGTTGATA
AAGACACGACCATCATGGAATTAAGAGATCGACTTCCTAAGAAGCAGCAAGCAAGTGCTTCCACTGATGGTGTCGATAAGCTTTCTGGGA
AAGAGCAGAGTTTTACTTCTTTGGAAGTTAGAAAAGTTGCTGAAACTAAAGAAAAGAGCAAGCATCTCAAAACCAAAACATGTAAAAAAG
TACAGGATGGCTTATCTGATATTGCAGAGAAATTCCTAAAGAAAGACCAGAGCGATGAAACTTCTGAAGATGATAAAAAGCAGAGCAAAA
AGGGAACTGAAGAAAAAAAGAAACCTTCAGACTTTAAGAAAAAAGTAATTAAAATGGAACAACAGTATGAATCTTCATCTGATGGCACTG
AAAAGTTACCTGAGCGAGAAGAAATTTGTCATTTTCCTAAGGGCATAAAACAAATTAAGAATGGAACAACTGATGGAGAAAAGAAAAGTA
AAAAAATAAGAGATAAAACTTCTAAAAAGAAGGATGAATTATCTGATTATGCTGAGAAGTCAACAGGGAAAGGAGATAGTTGTGACTCTT
CAGAGGATAAAAAGAGTAAGAATGGAGCATATGGTAGAGAGAAGAAAAGGTGCAAGTTGCTTGGAAAGAGTTCAAGGAAGAGACAAGATT
GTTCATCATCTGATACTGAGAAATATTCCATGAAAGAAGATGGTTGTAACTCTTCTGATAAGAGACTGAAAAGAATAGAATTGAGGGAAA
GAAGAAATTTAAGTTCAAAGAGAAATACTAAGGAAATACAAAGTGGCTCATCATCATCTGATGCTGAGGAAAGTTCTGAAGATAATAAAA
AGAAGAAGCAAAGAACTTCATCTAAAAAGAAGGCAGTCATTGTCAAGGAGAAAAAGAGAAACTCCCTAAGAACAAGCACTAAAAGGAAGC
AAGCTGACATTACATCCTCATCTTCTTCTGATATAGAAGATGATGATCAGAATTCTATAGGTGAGGGAAGCAGCGATGAACAGAAAATTA
AGCCTGTGACTGAAAATTTAGTGCTGTCTTCACATACTGGATTTTGCCAATCTTCAGGAGATGAAGCCTTATCTAAATCAGTGCCTGTCA
CAGTGGATGATGATGATGACGACAATGATCCTGAGAATAGAATTGCCAAGAAGATGCTTTTAGAAGAAATTAAAGCCAATCTTTCCTCTG
ATGAGGATGGATCTTCAGATGATGAGCCAGAAGAAGGGAAAAAAAGAACTGGAAAACAAAATGAAGAAAACCCAGGAGATGAGGAAGCAA
AAAATCAAGTCAATTCTGAATCAGATTCAGATTCTGAAGAATCTAAGAAGCCAAGATACAGACATAGGCTTTTGCGGCACAAATTGACTG
TGAGTGACGGAGAATCTGGAGAAGAAAAAAAGACAAAGCCTAAAGAGCATAAAGAAGTCAAAGGCAGAAACAGAAGAAAGGTGAGCAGTG
AAGATTCAGAAGATTCTGATTTTCAGGAATCAGGAGTTAGTGAAGAAGTTAGTGAATCCGAAGATGAACAGCGGCCCAGAACAAGGTCTG
CAAAGAAAGCAGAGTTGGAAGAAAATCAGCGGAGCTATAAACAGAAAAAGAAAAGGCGACGTATTAAGGTTCAAGAAGATTCATCCAGTG
AAAACAAGAGTAATTCTGAGGAAGAAGAGGAGGAAAAAGAAGAGGAGGAGGAAGAGGAGGAGGAGGAGGAAGAGGAGGAGGAAGATGAAA
ATGATGATTCCAAGTCTCCTGGAAAAGGCAGAAAGAAAATTCGGAAGATTCTTAAAGATGATAAACTGAGAACAGAAACACAAAATGCTC
TTAAGGAAGAGGAAGAGAGACGAAAACGTATTGCTGAGAGGGAGCGTGAGCGAGAAAAATTGAGAGAGGTGATAGAAATTGAAGATGCTT
CACCCACCAAGTGTCCAATAACAACCAAGTTGGTTTTAGATGAAGATGAAGAAACCAAAGAACCTTTAGTGCAGGTTCATAGAAATATGG
TTATCAAATTGAAACCCCATCAAGTAGATGGTGTTCAGTTTATGTGGGATTGCTGCTGTGAGTCTGTGAAAAAAACAAAGAAATCTCCAG
GTTCAGGATGCATTCTTGCCCACTGTATGGGCCTTGGTAAGACTTTACAGGTGGTAAGTTTTCTTCATACAGTTCTTTTGTGTGACAAAC
TGGATTTCAGCACGGCGTTAGTGGTTTGTCCTCTTAATACTGCTTTGAATTGGATGAATGAATTTGAGAAGTGGCAAGAGGGATTAAAAG
ATGATGAGAAGCTTGAGGTTTCTGAATTAGCAACTGTGAAACGTCCTCAGGAGAGAAGCTACATGCTGCAGAGGTGGCAAGAAGATGGTG
GTGTTATGATCATAGGCTATGAGATGTATAGAAATCTTGCTCAAGGAAGGAATGTGAAGAGTCGGAAACTTAAAGAAATATTTAACAAAG
CTTTGGTTGATCCAGGCCCTGATTTTGTTGTTTGTGATGAAGGCCATATTCTAAAAAATGAAGCATCTGCTGTTTCTAAAGCTATGAATT
CTATACGATCAAGGAGGAGGATTATTTTAACAGGAACACCACTTCAAAATAACCTAATTGAGTATCATTGTATGGTTAATTTTATCAAGG
AAAATTTACTTGGATCCATTAAGGAGTTCAGGAATAGATTTATAAATCCAATTCAAAATGGTCAGTGTGCAGATTCTACCATGGTAGATG
TCAGAGTGATGAAAAAACGTGCTCACATTCTCTATGAGATGTTAGCTGGATGTGTTCAGAGGAAAGATTATACAGCATTAACAAAATTCT
TGCCTCCAAAACACGAATATGTGTTAGCTGTGAGAATGACTTCTATTCAGTGCAAGCTCTATCAGTACTACTTAGATCACTTAACAGGTG
TGGGCAATAATAGTGAAGGTGGAAGAGGAAAGGCAGGTGCAAAGCTTTTCCAAGATTTTCAGATGTTAAGTAGAATATGGACTCATCCTT
GGTGTTTGCAGCTAGACTACATTAGCAAAGAAAATAAGGGTTATTTTGATGAAGACAGTATGGATGAATTTATAGCCTCAGATTCTGATG
AAACCTCCATGAGTTTAAGCTCCGATGATTATACAAAAAAGAAGAAAAAAGGGAAAAAGGGGAAAAAAGATAGTAGCTCAAGTGGAAGTG
GCAGTGACAATGATGTTGAAGTGATTAAGGTCTGGAATTCAAGATCTCGGGGAGGTGGTGAAGGAAATGTGGATGAAACAGGAAACAATC
CTTCTGTTTCTTTAAAACTGGAAGAAAGTAAAGCTACTTCTTCTTCTAATCCAAGCAGCCCAGCTCCAGACTGGTACAAAGATTTTGTTA
CAGATGCTGATGCTGAGGTTTTAGAGCATTCTGGGAAAATGGTACTTCTCTTTGAAATTCTTCGAATGGCAGAGGAAATTGGGGATAAAG
TCCTTGTTTTCAGCCAGTCCCTCATATCTCTGGACTTGATTGAAGATTTTCTTGAATTAGCTAGTAGGGAGAAGACAGAAGATAAAGATA
AACCCCTTATTTATAAAGGTGAGGGGAAGTGGCTTCGAAACATTGACTATTACCGTTTAGATGGTTCCACTACTGCACAGTCAAGGAAGA
AGTGGGCTGAAGAATTTAATGATGAAACTAATGTGAGAGGACGATTATTTATCATTTCTACTAAAGCAGGATCTCTAGGAATTAATCTGG
TAGCTGCTAATCGAGTAATTATATTCGACGCTTCTTGGAATCCATCTTATGACATCCAGAGTATATTCAGAGTTTATCGCTTTGGACAAA
CTAAGCCTGTTTATGTATATAGGTTCTTAGCTCAGGGAACCATGGAAGATAAGATTTATGATCGGCAAGTAACTAAGCAGTCACTGTCTT
TTCGAGTTGTTGATCAGCAGCAGGTGGAGCGTCATTTTACTATGAATGAGCTTACTGAACTTTATACTTTTGAGCCAGACTTATTAGATG
ACCCTAATTCAGAAAAGAAGAAGAAGAGGGATACTCCCATGCTGCCAAAGGATACCATACTTGCAGAGCTCCTTCAGATACATAAAGAAC
ACATTGTAGGATACCATGAACATGATTCTCTTTTGGACCACAAAGAAGAAGAAGAGTTGACTGAAGAAGAAAGAAAAGCAGCTTGGGCTG
AGTATGAAGCAGAGAAGAAGGGACTGACCATGCGTTTCAACATACCAACTGGGACCAATTTACCCCCTGTCAGTTTCAACTCTCAAACTC
CTTATATTCCTTTCAATTTGGGAGCCCTGTCAGCAATGAGTAATCAACAGCTGGAGGACCTCATTAATCAAGGAAGAGAAAAAGTTGTAG
AAGCAACAAACAGTGTGACAGCAGTGAGGATTCAACCTCTTGAGGATATAATTTCAGCTGTATGGAAGGAGAACATGAATCTCTCAGAGG
CCCAAGTACAGGCGTTAGCATTAAGTAGACAAGCCAGCCAGGAGCTTGATGTTAAACGAAGAGAAGCAATCTACAATGATGTATTGACAA
AACAACAGATGTCTGAACAAGTGTCGGAGGCCGAGTTACTCCCACAGCTGAGCAGAGCCCCATCCCAGGCTGCAGAAAGTAGTCCAGCAA
AGAAGGATGTACTGTATTCTCAGCCACCATCAAAGCCCATTCGTAGGAAATTCAGACCAGAAAACCAAGCTACAGAAAACCAAGAGCCTT
CCACTGCTGCAAGTGGGCCAGCTTCTGCGGCAACCATGAAACCGCATCCAACAGTCCAAAAGCAGTCTTCCAAACAGAAGAAGGCCATTC
AAACTGCTATCCGCAAAAATAAAGAGGCAAACGCAGTGCTGGCTCGGCTGAACAGTGAGCTCCAGCAGCAGCTCAAGGAGGTTCATCAAG
AACGAATTGCATTGGAAAACCAATTGGAACAACTTCGTCCGGTCACTGTGTTGTGACCCCCCCATGGTTCAAGTGACAGTGGGTGACCTT
GTCTGCCAAGATCTTTCTTTTGAATGTTTTGAACCCAACTACTTGTCATAGATGTTTGACTGTGTCAAAAGCTGTGAGCAGCAAAATATA
ATCCATATGACCTTTTCTCTTGCACTTCACTTGTATGTTTTACTGTGGTGGAAAAAATACTTCAACTGATTATCACACTTGAAATGCTAA
TTATCAGTGGAATTTGTCTCCTATTCTTAAGTACTTCTGCAAGGTATTAGATGCTGCTCCTTACCAAAAATCAGTCTTCTAGCAAATAAA
AATAACTTAGAGCATTATTTATTTAAAGAATTTATGTTTTCTATAAAACCTTATAACCAAGAACCTTCAGGATGCTTGTAACCAAGTACT
TTCAGGATGCTTTTTGTATGTATATCACATAGAGTAGGTTGGTTTCCTGAGTAATTGGGATTCCAACTAGATAGTCATTGGTGTGACCAT
AATAAAAACAAAAGCTAAAATAAAAGCATCAGATTTAGACTGGCGCTGTGCCCTCTACCACTATATGCCAAAAATTGCTTCTCTAGTGCC
ATTTTGATATTATATCTAGCTATAAATAATACATGACTATCGTTTTCTATTGAATGTCAAAGACTTACTGGGTCTTTACACCTCTGTAAA
GTGGAGGTTTTGGCAATGAGCTGTTTAACTTGGCCAAGCTAGGCTGTCAACCCAGACAACTCAGTCCTTTCATGTAAATTTTTGGGCAAG
AGAAGTCTGCTTTGACTGCCTTGCCTGACCAAATTAAATAAATAGTTGCCAGATCTCTACTTTTATCCTGCATGGGATAATATATCTGTA
AATGCATGAGTTTGGAAACCACCCATCAAATATGAAAGGCTGATGAGACTGTTAGGATTGATAAACATTTGTTGTTTGAACCCAGCTATC
CAAACTGGGGAAGAAGGGGAAATGGTTGTTACCAACAATCTCTAGTAGTTATTTTAATCTTTATTTTAACCTGGATTGCAAATGTATGGG
GTATGAGGAGATAATGAAAGAAAAGTGGTCCTCATGCTGGATATGTGACTGTTTTGTTCTCTGTAAAGTGTATTCTTGGGAAGTGATTGG
TTTATATCAGATTCAGAGGAGCCCAATTAACTCCAGTGTAGGTAATGTAAAACAGTAAGCTCAAATTGCAGAAGCCAGTATCCTACAGAA
ATTTAAGTAGCTACTGCTTCTCCTGAAAGCCCAAGTTGAAAATGGGACCACAGGGGCACAGGGCTACTGACCCTCACAGGGCATGCCAGC
GTTAACACCACTTTGAGAGACCAATGGCAAGAAATGCTGTCTCTTGTGCATTTTACTAATTTCCCCATTCTTAGGGTAGCAGGGTGGGGG
TGTATAGGGTCTTTTTGAAGCAGTTTTGGATAGGTTTGCAATATGTGGGATTCAGCCTTTGATTTCAATAGAGCTGAGAGCTTTTAGAAC
AAGCAGGCATTTATTTAATGTTTCCTTAGTCCATTGGCAAGCTTTATCAATAGCTTAATGGCAGAGGATAAAGGCTCAAACAGATGATGT
TTTTTCCACAGAAAAACAAATTGTTGAATCTATTCCGTGCATATTTAAGGATTTTGAATTGATTTTGAAAATCATGAAACTTGAACTATT
TTTCTATTCCCTTTTTTTCTTCCCCATTTGCTGCCTTTTTTGTTTTTGTGGGGGAAGGGTTGGGAGTAAGTTTAAACTCTTCCGAAGATT
ATGAATGGGTCAGCACAAATTTTTAGGCAACTGCTTTTTCCATGTTCTGAGATCTACGGGCTACAACAAATTTTATCAGCAGTGTTTTTT
GTTTTTTTGAGATGGAGACTTGCTCTGTCGCCCAGGCTGGAGCGCAGTGGCGCAATCTCGGCTCACTGCAACCTCCACCTCCTGGGTTCA
AGCAATTCTTGTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCCACCACCACGCTCAGCTAATTTTTGTATTTTTAGTAGAGATG
GGATTTTGTCATGTTGGCTAGGCTAGTCTCGAATTCCTGACCTCAAGTGATCCACCCGCCTTGGCCTCTCGAAGTGCTGGGATTACAGGC
GTGAGCCACCCGCCCGGCTATCAGCACTGTTCTGATTGCAGACGTTTCACAGCATGTTTGGCTTTTGGTAAATTCAATCCAGGAAAGACT
AGCATGTGCACTTTATCTCATAATCTTCCAGTACATATGCTCTCAGTTGGGATAGCAGTTCATTTCCATTAGGCAGACGTATAAACTAAG
GAATGTTAGTCTGCAGTATTCATTTTAAAAATATTGACATGCTTTTCCCCTCCCCTCCATGAAGTCAGTGCCAGAGTGAGCCAGATTGGG
AGGTTGGGGTTTTGTTTGGTTGGCTTGGTTTTCATTAAGGGAAAAAACTTGCATTGGACAATCAAATTCCCCTGAGTTTCATAATCTCAT
CAATATTTTAAGATAGGCGAGCACACACTAATAATATCTATGCCTACCTTCTTGGGTGGACTCAACTGTAACCACAGTTTATTAGTTGCT
TAGAAGTGGATTTTTAAAAAACAGTTAAATGTGTGTGCATAACACACAAGTAATGACACACTACTATTATTATTACCTAAGTAGTGCTCA
TCCTCTCTTTCTGTGTTTTCTTAGGATGTGCACTTTAATTTAGGATTGTAACGCCTAATAATATTTCTGTGAGCCTTTAATGTGATTTAT
AAGATGGCCGAATTACTGAAATCACCATTATACCTCTTCCATAAAACGACTCCAAAGTTAGACCTGCCTGTTGGGGAGAATTCTATAGAC
AGAAGGTCAATGTTGTCCCCATCCATAGGGGTTGAATTACCTTGCTGTTAAGTGGTCTTCCCCCATTGGGATCCTACAGTCCCACAGATG
AAAGCACAGTAGTAGCTGACAGCTGGCTTATTTGGTCCCTCGGCATCTCTCGTATGTGGCATATTGCTTTTGCCACTTTCCTATCCAGCA
GACATCAAAGCAAAACTAAAAGGTAGATATCTGGAATGAATGTATATGTTGTAATTGAGGCAGATATTTGCCTTAATTGGAAGGATCTAA
CTGCTTTACAAATATTAAACAAGTGCTTGGGCATGATTGGGAGAGGAGGCAGCTTAGCTGGAAGCTGTGCCCATCTTACTGTCACTGGAG
AATAGGATGTCAGAGCTGGGCAGGACTGGTACCCATCATTTGCAGTTTGCATGTGGGGAAACCAAAGCCCTAAGAAACAACAGTTCCTGG
CCCAAAAAATCCATAGAAAGAGGTAACTAGTGGCAGATTTGGGGCGCCAACCTGATTTTATGGATTTTGAGTTAGATTCTCTACCCTCTA
TCAATACTAAAAATAGATTAGGAGGGTTTTTTTTTCTGTTTATCATGTTGAATTTCATTGACTTAATTAGTCTTTAAATTTGAAAACATG
TTTTAGGGAGTTTAGTTCTAGAAATTTCTCTTAGATTGAAGTGACAGAATCTGAAAGAAAAGAATATGATTGAGCTATTTGTTTTCCTGA
ACACCTCACCTTTTATGATGCAATAAGTTACTCTGAGTTTCTTGGCAGAGTTTTTGACAGCTGTTGCTTTCAATGGATTCCATTCCTGTA
TTCCTTATGGGAGGTTGTTTTTAAAATAGACTACTGCGATTGAAATGAACTCAATATGTAGTTAAGTTATAGTTTTCTTCAATGTATTTT
TAGTTACTTGGGTCACAAATGTTCAATTTCAGCATATTTTAGGGTGAGTAATCAAAAATGTGAATTTGCCTTTGATTTCCTACCACTGTC
TGAGCTATCATAAAGCATTCTCTTTAGTTGTGATTTGATTCTATAGTCTGTTTCTAAATGACATTTGTCTGTTTCTTAAATGATCTCACA
GCCATGGTAATAATAGATGTGTACTCAGAAGATCAATAAGGTAATATTGGAATTCATGTGTTTTTTGCAATTAAGGCAGGCATTTGCCAA
TGTCTTCTTTTAAGCAGTAGTTGGAAACATCTCAATTACAGTGTAACACCTTAGAGCTAAAAACATTTGTTCAACACAAACTAGAATCAC
ACCTTCTCACTAGATATCACCAAGGGAATGTGGTTTTAAAAATAAAAAGAAAACAATATAACGTATCATGGCAACCAGAGCTTCCCATAT
TATTGACAAGTAGGGATCATTAGGTTCTGGTTTGAACATTCTGAATGTGAACAAAATGAAATAGTAGTTAAGAGGTGTTTTCCCACTGTG
TTTAAAGAGAACACTAGTAATTCTGGTTTTTCTTTCTAACTGCTTTACTGTTTCAAGGGTATTCTTTTAAAACTCTGATTTCAAAGGATC
AGTTGAATTTATACTTTAGTTATGGGTGTTTTGTTACTTTTTTTTTTTTTGTATCATGACTCAGTATGGTTCAATTTCCTAGTAAGAAGT
GGGGATTTGTGTTTTTGGAGTCCTCAGCTCACATGTCTTGTTCCTCCTTCAGCACAAGCTAGGGGAGATCCTACCAACACTGATAGGTCA
GTCATTGATGGCAATTTGAATGTGGGTATTACTCTGTGAGCCACCCTGCTTCGCTTGTTTGTAAGGAGAAATGCATCTGGTTATGTGAAT
TTCCCGAGAGCAGCAGACATGGAGGGCCAGACTTTAAAAGCAACGCAAGCAGATTCGAAGAGCTGTTGCCCTCTTCTAAAAAAGGCTTTT
GGAGGCTGTGTTACATGCATGCCCTAAAGCAGTCAGTCTGTTAGTATGAGCAAGACATCTGAAGTACACAGTTGCTTTTAGGCTTGTATA
GTTATTTTCTACACATGCCAACACACATGATGATAAAGGAACCTTTTCTAGGAGGCATTGCAGGGTTTCAATACACAGGACATGTTCTAG
TTACAGAAGCCTTGCTCTGCTGTCAACAATTGGGAAATGCTCATTTTTTCATGTTTTGTGAATACTCTGGTCTTGCTGTAAGCTAATGTC
ATGGCTGTGGGATATTAGAGAAGTGGGTTTATGACTCTGAAGACCAGCAGACACCAGACTTTAAAAGTGCTTAAATTGGAATTTGGAAAC
TACAGTAAAGAAACCTTCAGATACCAGTTCCATCCTGAAGCCCTCTGTTGAACAACAGGGCCAGATCCTAAAGCTCTTTCAGGGAGCTCT
TCTCTGGGGCTGGAACAGTTGATTATGCAACCCCATTGTGTGGAGATTGGATCAACTGAGTTGTGTTATTTTTGTTTTAAGTCACCTTGT
GCGAGAACCTCAACCGCACCTATCTTGGGAACCGGGTATACCCTTTTCTTTAGCACTGCTATCCTTTTTGTCTTCAGCACAAATAAGATG
TTCAAGTGAGCCAGAAGCAAGAAGAGCCATTTTAGTCTTCATAGCTATTGGCTAAGAGAGATAATGAGCTGATGGTCTATTTTAACCTTG
AAAGTAAAAATGTATATTTTTTCACTACAAGTACATTGAACAGTAAAAAGTGTAACAGCAAAGTATATATTTGATGCCTTCTGTCTTTTC
ATGATAATGTGCTAACAAGTTGTGTTAATATTTTACTCAGCCAGAGTCTCATTCATTTGCTAAGCATTGGGAACATTATGTATATTGACC
TTAAACATAGGTGTCCTATATTTGGATTGTGACTTGTAGACTCAAGCTAACCTTACTGCCTCTTTTTCACACTTGTTGAAAAGTCTGTGA

>8359_8359_4_ATRX-REPS2_ATRX_chrX_76776266_ENST00000395603_REPS2_chrX_17151947_ENST00000303843_length(amino acids)=2496AA_BP=2362
MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYV
ESDDEKPLDDETVNEDASNENSENDITMQSLPKEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDE
QCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKV
YEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSV
LADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKS
TGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKT
TAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPT
ETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIH
TNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFD
SSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRK
VAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHF
PKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK
EDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI
EDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEE
GKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESG
VSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK
KIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGV
QFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELAT
VKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTG
TPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVR
MTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYT
KKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSG
KMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNV
RGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERH
FTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMR
FNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQA
SQELDVKRREAIYNDVLTKQQMSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT

--------------------------------------------------------------
>8359_8359_5_ATRX-REPS2_ATRX_chrX_76776266_ENST00000395603_REPS2_chrX_17151947_ENST00000357277_length(transcript)=13497nt_BP=7301nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGTGAAAGCAAGTTGAATACATTGGTGCAGAAGCTTC
ATGACTTCCTTGCACACTCATCAGAAGAATCTGAAGAAACAAGTTCTCCTCCACGACTTGCAATGAATCAAAACACAGATAAAATCAGTG
GTTCTGGAAGTAACTCTGATATGATGGAAAACAGCAAGGAAGAGGGAACTAGCTCTTCAGAAAAATCCAAGTCTTCAGGATCGTCACGAT
CAAAGAGGAAACCTTCAATTGTAACAAAGTATGTAGAATCAGATGATGAAAAACCTTTGGATGATGAAACTGTAAATGAAGATGCGTCTA
ATGAAAATTCAGAAAATGATATTACTATGCAGAGCTTGCCAAAAGAAGATGGGCTTCATGGGATTGTGAGCTGCACTGCTTGTGGACAAC
AGGTCAATCATTTTCAAAAAGATTCCATTTATAGACACCCTTCATTGCAAGTTCTTATTTGTAAGAATTGCTTTAAGTATTACATGAGTG
ATGATATTAGCCGTGACTCAGATGGAATGGATGAACAATGTAGGTGGTGTGCGGAAGGTGGAAACTTGATTTGTTGTGACTTTTGCCATA
ATGCTTTCTGCAAGAAATGCATTCTACGCAACCTTGGTCGAAAGGAGTTGTCCACAATAATGGATGAAAACAACCAATGGTATTGCTACA
TTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAACAGCGTATTTGAGAATTTAGAACAGTTGTTGCAGCAAAATAAGAAGA
AGATAAAAGTTGACAGTGAAAAGAGTAATAAAGTATATGAACATACATCCAGATTTTCTCCAAAGAAGACTAGTTCAAATTGTAATGGAG
AAGAAAAGAAATTAGATGATTCCTGTTCTGGCTCTGTAACCTACTCTTATTCCGCACTAATTGTGCCCAAAGAGATGATTAAGAAGGCAA
AAAAACTGATTGAGACCACAGCCAACATGAACTCCAGTTATGTTAAATTTTTAAAGCAGGCAACAGATAATTCAGAAATCAGTTCTGCTA
CAAAATTACGTCAGCTTAAGGCTTTTAAGTCTGTGTTGGCTGATATTAAGAAGGCTCATCTTGCATTGGAAGAAGACTTAAATTCCGAGT
TTCGAGCGATGGATGCTGTAAACAAAGAGAAAAATACCAAAGAGCATAAAGTCATAGATGCTAAGTTTGAAACAAAAGCACGAAAAGGAG
AAAAACCTTGTGCTTTGGAAAAGAAGGATATTTCAAAGTCAGAAGCTAAACTTTCAAGAAAACAGGTAGATAGTGAGCACATGCATCAGA
ATGTTCCAACAGAGGAACAAAGAACAAATAAAAGTACCGGTGGTGAACATAAGAAATCTGATAGAAAAGAAGAACCTCAATATGAACCTG
CCAACACTTCTGAAGATTTAGACATGGATATTGTGTCTGTTCCTTCCTCAGTTCCAGAAGACATTTTTGAGAATCTTGAGACTGCTATGG
AAGTTCAGAGTTCAGTTGATCATCAAGGGGATGGCAGCAGTGGAACTGAACAAGAAGTGGAGAGTTCATCTGTAAAATTAAATATTTCTT
CAAAAGACAACAGAGGAGGTATTAAATCAAAAACTACAGCTAAAGTAACAAAAGAATTATATGTTAAACTCACTCCTGTTTCCCTTTCTA
ATTCCCCAATTAAAGGTGCTGATTGTCAGGAAGTTCCACAAGATAAAGATGGCTATAAAAGTTGTGGTCTGAACCCCAAGTTAGAGAAAT
GTGGACTTGGACAGGAAAACAGTGATAATGAGCATTTGGTTGAAAATGAAGTTTCATTACTTTTAGAGGAATCTGATCTTCGAAGATCCC
CACGTGTAAAGACTACACCCTTGAGGCGACCGACAGAAACTAACCCTGTAACATCTAATTCAGATGAAGAATGTAATGAAACAGTTAAGG
AGAAACAAAAACTATCAGTTCCAGTGAGAAAAAAGGATAAGCGTAATTCTTCTGACAGTGCTATAGATAATCCTAAGCCTAATAAATTGC
CAAAATCTAAGCAATCAGAGACTGTGGATCAAAATTCAGATTCTGATGAAATGCTAGCAATCCTCAAAGAGGTGAGCAGGATGAGTCACA
GTTCTTCTTCAGATACTGATATTAATGAAATTCATACAAACCATAAGACTTTGTATGATTTAAAGACTCAGGCGGGGAAAGATGATAAAG
GAAAAAGGAAACGAAAAAGTTCTACATCTGGCTCAGATTTTGATACTAAAAAGGGCAAATCAGCTAAGAGCTCTATAATTTCTAAAAAGA
AACGACAAACCCAGTCTGAGTCTTCTAATTATGACTCAGAATTAGAAAAAGAGATAAAGAGCATGAGTAAAATTGGTGCTGCCAGAACCA
CCAAAAAAAGAATTCCAAATACAAAAGATTTTGACTCTTCTGAAGATGAGAAACACAGCAAAAAAGGAATGGATAATCAAGGGCACAAAA
ATTTGAAGACCTCACAAGAAGGATCATCTGATGATGCTGAAAGAAAACAAGAGAGAGAGACTTTCTCTTCAGCAGAAGGCACAGTTGATA
AAGACACGACCATCATGGAATTAAGAGATCGACTTCCTAAGAAGCAGCAAGCAAGTGCTTCCACTGATGGTGTCGATAAGCTTTCTGGGA
AAGAGCAGAGTTTTACTTCTTTGGAAGTTAGAAAAGTTGCTGAAACTAAAGAAAAGAGCAAGCATCTCAAAACCAAAACATGTAAAAAAG
TACAGGATGGCTTATCTGATATTGCAGAGAAATTCCTAAAGAAAGACCAGAGCGATGAAACTTCTGAAGATGATAAAAAGCAGAGCAAAA
AGGGAACTGAAGAAAAAAAGAAACCTTCAGACTTTAAGAAAAAAGTAATTAAAATGGAACAACAGTATGAATCTTCATCTGATGGCACTG
AAAAGTTACCTGAGCGAGAAGAAATTTGTCATTTTCCTAAGGGCATAAAACAAATTAAGAATGGAACAACTGATGGAGAAAAGAAAAGTA
AAAAAATAAGAGATAAAACTTCTAAAAAGAAGGATGAATTATCTGATTATGCTGAGAAGTCAACAGGGAAAGGAGATAGTTGTGACTCTT
CAGAGGATAAAAAGAGTAAGAATGGAGCATATGGTAGAGAGAAGAAAAGGTGCAAGTTGCTTGGAAAGAGTTCAAGGAAGAGACAAGATT
GTTCATCATCTGATACTGAGAAATATTCCATGAAAGAAGATGGTTGTAACTCTTCTGATAAGAGACTGAAAAGAATAGAATTGAGGGAAA
GAAGAAATTTAAGTTCAAAGAGAAATACTAAGGAAATACAAAGTGGCTCATCATCATCTGATGCTGAGGAAAGTTCTGAAGATAATAAAA
AGAAGAAGCAAAGAACTTCATCTAAAAAGAAGGCAGTCATTGTCAAGGAGAAAAAGAGAAACTCCCTAAGAACAAGCACTAAAAGGAAGC
AAGCTGACATTACATCCTCATCTTCTTCTGATATAGAAGATGATGATCAGAATTCTATAGGTGAGGGAAGCAGCGATGAACAGAAAATTA
AGCCTGTGACTGAAAATTTAGTGCTGTCTTCACATACTGGATTTTGCCAATCTTCAGGAGATGAAGCCTTATCTAAATCAGTGCCTGTCA
CAGTGGATGATGATGATGACGACAATGATCCTGAGAATAGAATTGCCAAGAAGATGCTTTTAGAAGAAATTAAAGCCAATCTTTCCTCTG
ATGAGGATGGATCTTCAGATGATGAGCCAGAAGAAGGGAAAAAAAGAACTGGAAAACAAAATGAAGAAAACCCAGGAGATGAGGAAGCAA
AAAATCAAGTCAATTCTGAATCAGATTCAGATTCTGAAGAATCTAAGAAGCCAAGATACAGACATAGGCTTTTGCGGCACAAATTGACTG
TGAGTGACGGAGAATCTGGAGAAGAAAAAAAGACAAAGCCTAAAGAGCATAAAGAAGTCAAAGGCAGAAACAGAAGAAAGGTGAGCAGTG
AAGATTCAGAAGATTCTGATTTTCAGGAATCAGGAGTTAGTGAAGAAGTTAGTGAATCCGAAGATGAACAGCGGCCCAGAACAAGGTCTG
CAAAGAAAGCAGAGTTGGAAGAAAATCAGCGGAGCTATAAACAGAAAAAGAAAAGGCGACGTATTAAGGTTCAAGAAGATTCATCCAGTG
AAAACAAGAGTAATTCTGAGGAAGAAGAGGAGGAAAAAGAAGAGGAGGAGGAAGAGGAGGAGGAGGAGGAAGAGGAGGAGGAAGATGAAA
ATGATGATTCCAAGTCTCCTGGAAAAGGCAGAAAGAAAATTCGGAAGATTCTTAAAGATGATAAACTGAGAACAGAAACACAAAATGCTC
TTAAGGAAGAGGAAGAGAGACGAAAACGTATTGCTGAGAGGGAGCGTGAGCGAGAAAAATTGAGAGAGGTGATAGAAATTGAAGATGCTT
CACCCACCAAGTGTCCAATAACAACCAAGTTGGTTTTAGATGAAGATGAAGAAACCAAAGAACCTTTAGTGCAGGTTCATAGAAATATGG
TTATCAAATTGAAACCCCATCAAGTAGATGGTGTTCAGTTTATGTGGGATTGCTGCTGTGAGTCTGTGAAAAAAACAAAGAAATCTCCAG
GTTCAGGATGCATTCTTGCCCACTGTATGGGCCTTGGTAAGACTTTACAGGTGGTAAGTTTTCTTCATACAGTTCTTTTGTGTGACAAAC
TGGATTTCAGCACGGCGTTAGTGGTTTGTCCTCTTAATACTGCTTTGAATTGGATGAATGAATTTGAGAAGTGGCAAGAGGGATTAAAAG
ATGATGAGAAGCTTGAGGTTTCTGAATTAGCAACTGTGAAACGTCCTCAGGAGAGAAGCTACATGCTGCAGAGGTGGCAAGAAGATGGTG
GTGTTATGATCATAGGCTATGAGATGTATAGAAATCTTGCTCAAGGAAGGAATGTGAAGAGTCGGAAACTTAAAGAAATATTTAACAAAG
CTTTGGTTGATCCAGGCCCTGATTTTGTTGTTTGTGATGAAGGCCATATTCTAAAAAATGAAGCATCTGCTGTTTCTAAAGCTATGAATT
CTATACGATCAAGGAGGAGGATTATTTTAACAGGAACACCACTTCAAAATAACCTAATTGAGTATCATTGTATGGTTAATTTTATCAAGG
AAAATTTACTTGGATCCATTAAGGAGTTCAGGAATAGATTTATAAATCCAATTCAAAATGGTCAGTGTGCAGATTCTACCATGGTAGATG
TCAGAGTGATGAAAAAACGTGCTCACATTCTCTATGAGATGTTAGCTGGATGTGTTCAGAGGAAAGATTATACAGCATTAACAAAATTCT
TGCCTCCAAAACACGAATATGTGTTAGCTGTGAGAATGACTTCTATTCAGTGCAAGCTCTATCAGTACTACTTAGATCACTTAACAGGTG
TGGGCAATAATAGTGAAGGTGGAAGAGGAAAGGCAGGTGCAAAGCTTTTCCAAGATTTTCAGATGTTAAGTAGAATATGGACTCATCCTT
GGTGTTTGCAGCTAGACTACATTAGCAAAGAAAATAAGGGTTATTTTGATGAAGACAGTATGGATGAATTTATAGCCTCAGATTCTGATG
AAACCTCCATGAGTTTAAGCTCCGATGATTATACAAAAAAGAAGAAAAAAGGGAAAAAGGGGAAAAAAGATAGTAGCTCAAGTGGAAGTG
GCAGTGACAATGATGTTGAAGTGATTAAGGTCTGGAATTCAAGATCTCGGGGAGGTGGTGAAGGAAATGTGGATGAAACAGGAAACAATC
CTTCTGTTTCTTTAAAACTGGAAGAAAGTAAAGCTACTTCTTCTTCTAATCCAAGCAGCCCAGCTCCAGACTGGTACAAAGATTTTGTTA
CAGATGCTGATGCTGAGGTTTTAGAGCATTCTGGGAAAATGGTACTTCTCTTTGAAATTCTTCGAATGGCAGAGGAAATTGGGGATAAAG
TCCTTGTTTTCAGCCAGTCCCTCATATCTCTGGACTTGATTGAAGATTTTCTTGAATTAGCTAGTAGGGAGAAGACAGAAGATAAAGATA
AACCCCTTATTTATAAAGGTGAGGGGAAGTGGCTTCGAAACATTGACTATTACCGTTTAGATGGTTCCACTACTGCACAGTCAAGGAAGA
AGTGGGCTGAAGAATTTAATGATGAAACTAATGTGAGAGGACGATTATTTATCATTTCTACTAAAGCAGGATCTCTAGGAATTAATCTGG
TAGCTGCTAATCGAGTAATTATATTCGACGCTTCTTGGAATCCATCTTATGACATCCAGAGTATATTCAGAGTTTATCGCTTTGGACAAA
CTAAGCCTGTTTATGTATATAGGTTCTTAGCTCAGGGAACCATGGAAGATAAGATTTATGATCGGCAAGTAACTAAGCAGTCACTGTCTT
TTCGAGTTGTTGATCAGCAGCAGGTGGAGCGTCATTTTACTATGAATGAGCTTACTGAACTTTATACTTTTGAGCCAGACTTATTAGATG
ACCCTAATTCAGAAAAGAAGAAGAAGAGGGATACTCCCATGCTGCCAAAGGATACCATACTTGCAGAGCTCCTTCAGATACATAAAGAAC
ACATTGTAGGATACCATGAACATGATTCTCTTTTGGACCACAAAGAAGAAGAAGAGTTGACTGAAGAAGAAAGAAAAGCAGCTTGGGCTG
AGTATGAAGCAGAGAAGAAGGGACTGACCATGCGTTTCAACATACCAACTGGGACCAATTTACCCCCTGTCAGTTTCAACTCTCAAACTC
CTTATATTCCTTTCAATTTGGGAGCCCTGTCAGCAATGAGTAATCAACAGCTGGAGGACCTCATTAATCAAGGAAGAGAAAAAGTTGTAG
AAGCAACAAACAGTGTGACAGCAGTGAGGATTCAACCTCTTGAGGATATAATTTCAGCTGTATGGAAGGAGAACATGAATCTCTCAGAGG
CCCAAGTACAGGCGTTAGCATTAAGTAGACAAGCCAGCCAGGAGCTTGATGTTAAACGAAGAGAAGCAATCTACAATGATGTATTGACAA
AACAACAGATGTCTGAACAAGTGTCGGAGGCCGAGTTACTCCCACAGCTGAGCAGAGCCCCATCCCAGGCTGCAGAAAGTAGTCCAGCAA
AGAAGGATGTACTGTATTCTCAGCCACCATCAAAGCCCATTCGTAGGAAATTCAGACCAGAAAACCAAGCTACAGAAAACCAAGAGCCTT
CCACTGCTGCAAGTGGGCCAGCTTCTGCGGCAACCATGAAACCGCATCCAACAGTCCAAAAGCAGTCTTCCAAACAGAAGAAGGCCATTC
AAACTGCTATCCGCAAAAATAAAGAGGCAAACGCAGTGCTGGCTCGGCTGAACAGTGAGCTCCAGCAGCAGCTCAAGGAGGTTCATCAAG
AACGAATTGCATTGGAAAACCAATTGGAACAACTTCGTCCGGTCACTGTGTTGTGACCCCCCCATGGTTCAAGTGACAGTGGGTGACCTT
GTCTGCCAAGATCTTTCTTTTGAATGTTTTGAACCCAACTACTTGTCATAGATGTTTGACTGTGTCAAAAGCTGTGAGCAGCAAAATATA
ATCCATATGACCTTTTCTCTTGCACTTCACTTGTATGTTTTACTGTGGTGGAAAAAATACTTCAACTGATTATCACACTTGAAATGCTAA
TTATCAGTGGAATTTGTCTCCTATTCTTAAGTACTTCTGCAAGGTATTAGATGCTGCTCCTTACCAAAAATCAGTCTTCTAGCAAATAAA
AATAACTTAGAGCATTATTTATTTAAAGAATTTATGTTTTCTATAAAACCTTATAACCAAGAACCTTCAGGATGCTTGTAACCAAGTACT
TTCAGGATGCTTTTTGTATGTATATCACATAGAGTAGGTTGGTTTCCTGAGTAATTGGGATTCCAACTAGATAGTCATTGGTGTGACCAT
AATAAAAACAAAAGCTAAAATAAAAGCATCAGATTTAGACTGGCGCTGTGCCCTCTACCACTATATGCCAAAAATTGCTTCTCTAGTGCC
ATTTTGATATTATATCTAGCTATAAATAATACATGACTATCGTTTTCTATTGAATGTCAAAGACTTACTGGGTCTTTACACCTCTGTAAA
GTGGAGGTTTTGGCAATGAGCTGTTTAACTTGGCCAAGCTAGGCTGTCAACCCAGACAACTCAGTCCTTTCATGTAAATTTTTGGGCAAG
AGAAGTCTGCTTTGACTGCCTTGCCTGACCAAATTAAATAAATAGTTGCCAGATCTCTACTTTTATCCTGCATGGGATAATATATCTGTA
AATGCATGAGTTTGGAAACCACCCATCAAATATGAAAGGCTGATGAGACTGTTAGGATTGATAAACATTTGTTGTTTGAACCCAGCTATC
CAAACTGGGGAAGAAGGGGAAATGGTTGTTACCAACAATCTCTAGTAGTTATTTTAATCTTTATTTTAACCTGGATTGCAAATGTATGGG
GTATGAGGAGATAATGAAAGAAAAGTGGTCCTCATGCTGGATATGTGACTGTTTTGTTCTCTGTAAAGTGTATTCTTGGGAAGTGATTGG
TTTATATCAGATTCAGAGGAGCCCAATTAACTCCAGTGTAGGTAATGTAAAACAGTAAGCTCAAATTGCAGAAGCCAGTATCCTACAGAA
ATTTAAGTAGCTACTGCTTCTCCTGAAAGCCCAAGTTGAAAATGGGACCACAGGGGCACAGGGCTACTGACCCTCACAGGGCATGCCAGC
GTTAACACCACTTTGAGAGACCAATGGCAAGAAATGCTGTCTCTTGTGCATTTTACTAATTTCCCCATTCTTAGGGTAGCAGGGTGGGGG
TGTATAGGGTCTTTTTGAAGCAGTTTTGGATAGGTTTGCAATATGTGGGATTCAGCCTTTGATTTCAATAGAGCTGAGAGCTTTTAGAAC
AAGCAGGCATTTATTTAATGTTTCCTTAGTCCATTGGCAAGCTTTATCAATAGCTTAATGGCAGAGGATAAAGGCTCAAACAGATGATGT
TTTTTCCACAGAAAAACAAATTGTTGAATCTATTCCGTGCATATTTAAGGATTTTGAATTGATTTTGAAAATCATGAAACTTGAACTATT
TTTCTATTCCCTTTTTTTCTTCCCCATTTGCTGCCTTTTTTGTTTTTGTGGGGGAAGGGTTGGGAGTAAGTTTAAACTCTTCCGAAGATT
ATGAATGGGTCAGCACAAATTTTTAGGCAACTGCTTTTTCCATGTTCTGAGATCTACGGGCTACAACAAATTTTATCAGCAGTGTTTTTT
GTTTTTTTGAGATGGAGACTTGCTCTGTCGCCCAGGCTGGAGCGCAGTGGCGCAATCTCGGCTCACTGCAACCTCCACCTCCTGGGTTCA
AGCAATTCTTGTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCCACCACCACGCTCAGCTAATTTTTGTATTTTTAGTAGAGATG
GGATTTTGTCATGTTGGCTAGGCTAGTCTCGAATTCCTGACCTCAAGTGATCCACCCGCCTTGGCCTCTCGAAGTGCTGGGATTACAGGC
GTGAGCCACCCGCCCGGCTATCAGCACTGTTCTGATTGCAGACGTTTCACAGCATGTTTGGCTTTTGGTAAATTCAATCCAGGAAAGACT
AGCATGTGCACTTTATCTCATAATCTTCCAGTACATATGCTCTCAGTTGGGATAGCAGTTCATTTCCATTAGGCAGACGTATAAACTAAG
GAATGTTAGTCTGCAGTATTCATTTTAAAAATATTGACATGCTTTTCCCCTCCCCTCCATGAAGTCAGTGCCAGAGTGAGCCAGATTGGG
AGGTTGGGGTTTTGTTTGGTTGGCTTGGTTTTCATTAAGGGAAAAAACTTGCATTGGACAATCAAATTCCCCTGAGTTTCATAATCTCAT
CAATATTTTAAGATAGGCGAGCACACACTAATAATATCTATGCCTACCTTCTTGGGTGGACTCAACTGTAACCACAGTTTATTAGTTGCT
TAGAAGTGGATTTTTAAAAAACAGTTAAATGTGTGTGCATAACACACAAGTAATGACACACTACTATTATTATTACCTAAGTAGTGCTCA
TCCTCTCTTTCTGTGTTTTCTTAGGATGTGCACTTTAATTTAGGATTGTAACGCCTAATAATATTTCTGTGAGCCTTTAATGTGATTTAT
AAGATGGCCGAATTACTGAAATCACCATTATACCTCTTCCATAAAACGACTCCAAAGTTAGACCTGCCTGTTGGGGAGAATTCTATAGAC
AGAAGGTCAATGTTGTCCCCATCCATAGGGGTTGAATTACCTTGCTGTTAAGTGGTCTTCCCCCATTGGGATCCTACAGTCCCACAGATG
AAAGCACAGTAGTAGCTGACAGCTGGCTTATTTGGTCCCTCGGCATCTCTCGTATGTGGCATATTGCTTTTGCCACTTTCCTATCCAGCA
GACATCAAAGCAAAACTAAAAGGTAGATATCTGGAATGAATGTATATGTTGTAATTGAGGCAGATATTTGCCTTAATTGGAAGGATCTAA
CTGCTTTACAAATATTAAACAAGTGCTTGGGCATGATTGGGAGAGGAGGCAGCTTAGCTGGAAGCTGTGCCCATCTTACTGTCACTGGAG
AATAGGATGTCAGAGCTGGGCAGGACTGGTACCCATCATTTGCAGTTTGCATGTGGGGAAACCAAAGCCCTAAGAAACAACAGTTCCTGG
CCCAAAAAATCCATAGAAAGAGGTAACTAGTGGCAGATTTGGGGCGCCAACCTGATTTTATGGATTTTGAGTTAGATTCTCTACCCTCTA
TCAATACTAAAAATAGATTAGGAGGGTTTTTTTTTCTGTTTATCATGTTGAATTTCATTGACTTAATTAGTCTTTAAATTTGAAAACATG
TTTTAGGGAGTTTAGTTCTAGAAATTTCTCTTAGATTGAAGTGACAGAATCTGAAAGAAAAGAATATGATTGAGCTATTTGTTTTCCTGA
ACACCTCACCTTTTATGATGCAATAAGTTACTCTGAGTTTCTTGGCAGAGTTTTTGACAGCTGTTGCTTTCAATGGATTCCATTCCTGTA
TTCCTTATGGGAGGTTGTTTTTAAAATAGACTACTGCGATTGAAATGAACTCAATATGTAGTTAAGTTATAGTTTTCTTCAATGTATTTT
TAGTTACTTGGGTCACAAATGTTCAATTTCAGCATATTTTAGGGTGAGTAATCAAAAATGTGAATTTGCCTTTGATTTCCTACCACTGTC
TGAGCTATCATAAAGCATTCTCTTTAGTTGTGATTTGATTCTATAGTCTGTTTCTAAATGACATTTGTCTGTTTCTTAAATGATCTCACA
GCCATGGTAATAATAGATGTGTACTCAGAAGATCAATAAGGTAATATTGGAATTCATGTGTTTTTTGCAATTAAGGCAGGCATTTGCCAA
TGTCTTCTTTTAAGCAGTAGTTGGAAACATCTCAATTACAGTGTAACACCTTAGAGCTAAAAACATTTGTTCAACACAAACTAGAATCAC
ACCTTCTCACTAGATATCACCAAGGGAATGTGGTTTTAAAAATAAAAAGAAAACAATATAACGTATCATGGCAACCAGAGCTTCCCATAT
TATTGACAAGTAGGGATCATTAGGTTCTGGTTTGAACATTCTGAATGTGAACAAAATGAAATAGTAGTTAAGAGGTGTTTTCCCACTGTG
TTTAAAGAGAACACTAGTAATTCTGGTTTTTCTTTCTAACTGCTTTACTGTTTCAAGGGTATTCTTTTAAAACTCTGATTTCAAAGGATC
AGTTGAATTTATACTTTAGTTATGGGTGTTTTGTTACTTTTTTTTTTTTTGTATCATGACTCAGTATGGTTCAATTTCCTAGTAAGAAGT
GGGGATTTGTGTTTTTGGAGTCCTCAGCTCACATGTCTTGTTCCTCCTTCAGCACAAGCTAGGGGAGATCCTACCAACACTGATAGGTCA
GTCATTGATGGCAATTTGAATGTGGGTATTACTCTGTGAGCCACCCTGCTTCGCTTGTTTGTAAGGAGAAATGCATCTGGTTATGTGAAT
TTCCCGAGAGCAGCAGACATGGAGGGCCAGACTTTAAAAGCAACGCAAGCAGATTCGAAGAGCTGTTGCCCTCTTCTAAAAAAGGCTTTT
GGAGGCTGTGTTACATGCATGCCCTAAAGCAGTCAGTCTGTTAGTATGAGCAAGACATCTGAAGTACACAGTTGCTTTTAGGCTTGTATA
GTTATTTTCTACACATGCCAACACACATGATGATAAAGGAACCTTTTCTAGGAGGCATTGCAGGGTTTCAATACACAGGACATGTTCTAG
TTACAGAAGCCTTGCTCTGCTGTCAACAATTGGGAAATGCTCATTTTTTCATGTTTTGTGAATACTCTGGTCTTGCTGTAAGCTAATGTC
ATGGCTGTGGGATATTAGAGAAGTGGGTTTATGACTCTGAAGACCAGCAGACACCAGACTTTAAAAGTGCTTAAATTGGAATTTGGAAAC
TACAGTAAAGAAACCTTCAGATACCAGTTCCATCCTGAAGCCCTCTGTTGAACAACAGGGCCAGATCCTAAAGCTCTTTCAGGGAGCTCT
TCTCTGGGGCTGGAACAGTTGATTATGCAACCCCATTGTGTGGAGATTGGATCAACTGAGTTGTGTTATTTTTGTTTTAAGTCACCTTGT
GCGAGAACCTCAACCGCACCTATCTTGGGAACCGGGTATACCCTTTTCTTTAGCACTGCTATCCTTTTTGTCTTCAGCACAAATAAGATG
TTCAAGTGAGCCAGAAGCAAGAAGAGCCATTTTAGTCTTCATAGCTATTGGCTAAGAGAGATAATGAGCTGATGGTCTATTTTAACCTTG
AAAGTAAAAATGTATATTTTTTCACTACAAGTACATTGAACAGTAAAAAGTGTAACAGCAAAGTATATATTTGATGCCTTCTGTCTTTTC
ATGATAATGTGCTAACAAGTTGTGTTAATATTTTACTCAGCCAGAGTCTCATTCATTTGCTAAGCATTGGGAACATTATGTATATTGACC
TTAAACATAGGTGTCCTATATTTGGATTGTGACTTGTAGACTCAAGCTAACCTTACTGCCTCTTTTTCACACTTGTTGAAAAGTCTGTGA

>8359_8359_5_ATRX-REPS2_ATRX_chrX_76776266_ENST00000395603_REPS2_chrX_17151947_ENST00000357277_length(amino acids)=2496AA_BP=2362
MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYV
ESDDEKPLDDETVNEDASNENSENDITMQSLPKEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDE
QCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKV
YEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSV
LADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKS
TGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKT
TAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPT
ETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIH
TNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFD
SSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRK
VAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHF
PKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK
EDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI
EDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEE
GKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESG
VSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK
KIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGV
QFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELAT
VKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTG
TPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVR
MTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYT
KKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSG
KMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNV
RGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERH
FTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMR
FNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQA
SQELDVKRREAIYNDVLTKQQMSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT

--------------------------------------------------------------
>8359_8359_6_ATRX-REPS2_ATRX_chrX_76776266_ENST00000395603_REPS2_chrX_17151947_ENST00000380064_length(transcript)=7847nt_BP=7301nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGTGAAAGCAAGTTGAATACATTGGTGCAGAAGCTTC
ATGACTTCCTTGCACACTCATCAGAAGAATCTGAAGAAACAAGTTCTCCTCCACGACTTGCAATGAATCAAAACACAGATAAAATCAGTG
GTTCTGGAAGTAACTCTGATATGATGGAAAACAGCAAGGAAGAGGGAACTAGCTCTTCAGAAAAATCCAAGTCTTCAGGATCGTCACGAT
CAAAGAGGAAACCTTCAATTGTAACAAAGTATGTAGAATCAGATGATGAAAAACCTTTGGATGATGAAACTGTAAATGAAGATGCGTCTA
ATGAAAATTCAGAAAATGATATTACTATGCAGAGCTTGCCAAAAGAAGATGGGCTTCATGGGATTGTGAGCTGCACTGCTTGTGGACAAC
AGGTCAATCATTTTCAAAAAGATTCCATTTATAGACACCCTTCATTGCAAGTTCTTATTTGTAAGAATTGCTTTAAGTATTACATGAGTG
ATGATATTAGCCGTGACTCAGATGGAATGGATGAACAATGTAGGTGGTGTGCGGAAGGTGGAAACTTGATTTGTTGTGACTTTTGCCATA
ATGCTTTCTGCAAGAAATGCATTCTACGCAACCTTGGTCGAAAGGAGTTGTCCACAATAATGGATGAAAACAACCAATGGTATTGCTACA
TTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAACAGCGTATTTGAGAATTTAGAACAGTTGTTGCAGCAAAATAAGAAGA
AGATAAAAGTTGACAGTGAAAAGAGTAATAAAGTATATGAACATACATCCAGATTTTCTCCAAAGAAGACTAGTTCAAATTGTAATGGAG
AAGAAAAGAAATTAGATGATTCCTGTTCTGGCTCTGTAACCTACTCTTATTCCGCACTAATTGTGCCCAAAGAGATGATTAAGAAGGCAA
AAAAACTGATTGAGACCACAGCCAACATGAACTCCAGTTATGTTAAATTTTTAAAGCAGGCAACAGATAATTCAGAAATCAGTTCTGCTA
CAAAATTACGTCAGCTTAAGGCTTTTAAGTCTGTGTTGGCTGATATTAAGAAGGCTCATCTTGCATTGGAAGAAGACTTAAATTCCGAGT
TTCGAGCGATGGATGCTGTAAACAAAGAGAAAAATACCAAAGAGCATAAAGTCATAGATGCTAAGTTTGAAACAAAAGCACGAAAAGGAG
AAAAACCTTGTGCTTTGGAAAAGAAGGATATTTCAAAGTCAGAAGCTAAACTTTCAAGAAAACAGGTAGATAGTGAGCACATGCATCAGA
ATGTTCCAACAGAGGAACAAAGAACAAATAAAAGTACCGGTGGTGAACATAAGAAATCTGATAGAAAAGAAGAACCTCAATATGAACCTG
CCAACACTTCTGAAGATTTAGACATGGATATTGTGTCTGTTCCTTCCTCAGTTCCAGAAGACATTTTTGAGAATCTTGAGACTGCTATGG
AAGTTCAGAGTTCAGTTGATCATCAAGGGGATGGCAGCAGTGGAACTGAACAAGAAGTGGAGAGTTCATCTGTAAAATTAAATATTTCTT
CAAAAGACAACAGAGGAGGTATTAAATCAAAAACTACAGCTAAAGTAACAAAAGAATTATATGTTAAACTCACTCCTGTTTCCCTTTCTA
ATTCCCCAATTAAAGGTGCTGATTGTCAGGAAGTTCCACAAGATAAAGATGGCTATAAAAGTTGTGGTCTGAACCCCAAGTTAGAGAAAT
GTGGACTTGGACAGGAAAACAGTGATAATGAGCATTTGGTTGAAAATGAAGTTTCATTACTTTTAGAGGAATCTGATCTTCGAAGATCCC
CACGTGTAAAGACTACACCCTTGAGGCGACCGACAGAAACTAACCCTGTAACATCTAATTCAGATGAAGAATGTAATGAAACAGTTAAGG
AGAAACAAAAACTATCAGTTCCAGTGAGAAAAAAGGATAAGCGTAATTCTTCTGACAGTGCTATAGATAATCCTAAGCCTAATAAATTGC
CAAAATCTAAGCAATCAGAGACTGTGGATCAAAATTCAGATTCTGATGAAATGCTAGCAATCCTCAAAGAGGTGAGCAGGATGAGTCACA
GTTCTTCTTCAGATACTGATATTAATGAAATTCATACAAACCATAAGACTTTGTATGATTTAAAGACTCAGGCGGGGAAAGATGATAAAG
GAAAAAGGAAACGAAAAAGTTCTACATCTGGCTCAGATTTTGATACTAAAAAGGGCAAATCAGCTAAGAGCTCTATAATTTCTAAAAAGA
AACGACAAACCCAGTCTGAGTCTTCTAATTATGACTCAGAATTAGAAAAAGAGATAAAGAGCATGAGTAAAATTGGTGCTGCCAGAACCA
CCAAAAAAAGAATTCCAAATACAAAAGATTTTGACTCTTCTGAAGATGAGAAACACAGCAAAAAAGGAATGGATAATCAAGGGCACAAAA
ATTTGAAGACCTCACAAGAAGGATCATCTGATGATGCTGAAAGAAAACAAGAGAGAGAGACTTTCTCTTCAGCAGAAGGCACAGTTGATA
AAGACACGACCATCATGGAATTAAGAGATCGACTTCCTAAGAAGCAGCAAGCAAGTGCTTCCACTGATGGTGTCGATAAGCTTTCTGGGA
AAGAGCAGAGTTTTACTTCTTTGGAAGTTAGAAAAGTTGCTGAAACTAAAGAAAAGAGCAAGCATCTCAAAACCAAAACATGTAAAAAAG
TACAGGATGGCTTATCTGATATTGCAGAGAAATTCCTAAAGAAAGACCAGAGCGATGAAACTTCTGAAGATGATAAAAAGCAGAGCAAAA
AGGGAACTGAAGAAAAAAAGAAACCTTCAGACTTTAAGAAAAAAGTAATTAAAATGGAACAACAGTATGAATCTTCATCTGATGGCACTG
AAAAGTTACCTGAGCGAGAAGAAATTTGTCATTTTCCTAAGGGCATAAAACAAATTAAGAATGGAACAACTGATGGAGAAAAGAAAAGTA
AAAAAATAAGAGATAAAACTTCTAAAAAGAAGGATGAATTATCTGATTATGCTGAGAAGTCAACAGGGAAAGGAGATAGTTGTGACTCTT
CAGAGGATAAAAAGAGTAAGAATGGAGCATATGGTAGAGAGAAGAAAAGGTGCAAGTTGCTTGGAAAGAGTTCAAGGAAGAGACAAGATT
GTTCATCATCTGATACTGAGAAATATTCCATGAAAGAAGATGGTTGTAACTCTTCTGATAAGAGACTGAAAAGAATAGAATTGAGGGAAA
GAAGAAATTTAAGTTCAAAGAGAAATACTAAGGAAATACAAAGTGGCTCATCATCATCTGATGCTGAGGAAAGTTCTGAAGATAATAAAA
AGAAGAAGCAAAGAACTTCATCTAAAAAGAAGGCAGTCATTGTCAAGGAGAAAAAGAGAAACTCCCTAAGAACAAGCACTAAAAGGAAGC
AAGCTGACATTACATCCTCATCTTCTTCTGATATAGAAGATGATGATCAGAATTCTATAGGTGAGGGAAGCAGCGATGAACAGAAAATTA
AGCCTGTGACTGAAAATTTAGTGCTGTCTTCACATACTGGATTTTGCCAATCTTCAGGAGATGAAGCCTTATCTAAATCAGTGCCTGTCA
CAGTGGATGATGATGATGACGACAATGATCCTGAGAATAGAATTGCCAAGAAGATGCTTTTAGAAGAAATTAAAGCCAATCTTTCCTCTG
ATGAGGATGGATCTTCAGATGATGAGCCAGAAGAAGGGAAAAAAAGAACTGGAAAACAAAATGAAGAAAACCCAGGAGATGAGGAAGCAA
AAAATCAAGTCAATTCTGAATCAGATTCAGATTCTGAAGAATCTAAGAAGCCAAGATACAGACATAGGCTTTTGCGGCACAAATTGACTG
TGAGTGACGGAGAATCTGGAGAAGAAAAAAAGACAAAGCCTAAAGAGCATAAAGAAGTCAAAGGCAGAAACAGAAGAAAGGTGAGCAGTG
AAGATTCAGAAGATTCTGATTTTCAGGAATCAGGAGTTAGTGAAGAAGTTAGTGAATCCGAAGATGAACAGCGGCCCAGAACAAGGTCTG
CAAAGAAAGCAGAGTTGGAAGAAAATCAGCGGAGCTATAAACAGAAAAAGAAAAGGCGACGTATTAAGGTTCAAGAAGATTCATCCAGTG
AAAACAAGAGTAATTCTGAGGAAGAAGAGGAGGAAAAAGAAGAGGAGGAGGAAGAGGAGGAGGAGGAGGAAGAGGAGGAGGAAGATGAAA
ATGATGATTCCAAGTCTCCTGGAAAAGGCAGAAAGAAAATTCGGAAGATTCTTAAAGATGATAAACTGAGAACAGAAACACAAAATGCTC
TTAAGGAAGAGGAAGAGAGACGAAAACGTATTGCTGAGAGGGAGCGTGAGCGAGAAAAATTGAGAGAGGTGATAGAAATTGAAGATGCTT
CACCCACCAAGTGTCCAATAACAACCAAGTTGGTTTTAGATGAAGATGAAGAAACCAAAGAACCTTTAGTGCAGGTTCATAGAAATATGG
TTATCAAATTGAAACCCCATCAAGTAGATGGTGTTCAGTTTATGTGGGATTGCTGCTGTGAGTCTGTGAAAAAAACAAAGAAATCTCCAG
GTTCAGGATGCATTCTTGCCCACTGTATGGGCCTTGGTAAGACTTTACAGGTGGTAAGTTTTCTTCATACAGTTCTTTTGTGTGACAAAC
TGGATTTCAGCACGGCGTTAGTGGTTTGTCCTCTTAATACTGCTTTGAATTGGATGAATGAATTTGAGAAGTGGCAAGAGGGATTAAAAG
ATGATGAGAAGCTTGAGGTTTCTGAATTAGCAACTGTGAAACGTCCTCAGGAGAGAAGCTACATGCTGCAGAGGTGGCAAGAAGATGGTG
GTGTTATGATCATAGGCTATGAGATGTATAGAAATCTTGCTCAAGGAAGGAATGTGAAGAGTCGGAAACTTAAAGAAATATTTAACAAAG
CTTTGGTTGATCCAGGCCCTGATTTTGTTGTTTGTGATGAAGGCCATATTCTAAAAAATGAAGCATCTGCTGTTTCTAAAGCTATGAATT
CTATACGATCAAGGAGGAGGATTATTTTAACAGGAACACCACTTCAAAATAACCTAATTGAGTATCATTGTATGGTTAATTTTATCAAGG
AAAATTTACTTGGATCCATTAAGGAGTTCAGGAATAGATTTATAAATCCAATTCAAAATGGTCAGTGTGCAGATTCTACCATGGTAGATG
TCAGAGTGATGAAAAAACGTGCTCACATTCTCTATGAGATGTTAGCTGGATGTGTTCAGAGGAAAGATTATACAGCATTAACAAAATTCT
TGCCTCCAAAACACGAATATGTGTTAGCTGTGAGAATGACTTCTATTCAGTGCAAGCTCTATCAGTACTACTTAGATCACTTAACAGGTG
TGGGCAATAATAGTGAAGGTGGAAGAGGAAAGGCAGGTGCAAAGCTTTTCCAAGATTTTCAGATGTTAAGTAGAATATGGACTCATCCTT
GGTGTTTGCAGCTAGACTACATTAGCAAAGAAAATAAGGGTTATTTTGATGAAGACAGTATGGATGAATTTATAGCCTCAGATTCTGATG
AAACCTCCATGAGTTTAAGCTCCGATGATTATACAAAAAAGAAGAAAAAAGGGAAAAAGGGGAAAAAAGATAGTAGCTCAAGTGGAAGTG
GCAGTGACAATGATGTTGAAGTGATTAAGGTCTGGAATTCAAGATCTCGGGGAGGTGGTGAAGGAAATGTGGATGAAACAGGAAACAATC
CTTCTGTTTCTTTAAAACTGGAAGAAAGTAAAGCTACTTCTTCTTCTAATCCAAGCAGCCCAGCTCCAGACTGGTACAAAGATTTTGTTA
CAGATGCTGATGCTGAGGTTTTAGAGCATTCTGGGAAAATGGTACTTCTCTTTGAAATTCTTCGAATGGCAGAGGAAATTGGGGATAAAG
TCCTTGTTTTCAGCCAGTCCCTCATATCTCTGGACTTGATTGAAGATTTTCTTGAATTAGCTAGTAGGGAGAAGACAGAAGATAAAGATA
AACCCCTTATTTATAAAGGTGAGGGGAAGTGGCTTCGAAACATTGACTATTACCGTTTAGATGGTTCCACTACTGCACAGTCAAGGAAGA
AGTGGGCTGAAGAATTTAATGATGAAACTAATGTGAGAGGACGATTATTTATCATTTCTACTAAAGCAGGATCTCTAGGAATTAATCTGG
TAGCTGCTAATCGAGTAATTATATTCGACGCTTCTTGGAATCCATCTTATGACATCCAGAGTATATTCAGAGTTTATCGCTTTGGACAAA
CTAAGCCTGTTTATGTATATAGGTTCTTAGCTCAGGGAACCATGGAAGATAAGATTTATGATCGGCAAGTAACTAAGCAGTCACTGTCTT
TTCGAGTTGTTGATCAGCAGCAGGTGGAGCGTCATTTTACTATGAATGAGCTTACTGAACTTTATACTTTTGAGCCAGACTTATTAGATG
ACCCTAATTCAGAAAAGAAGAAGAAGAGGGATACTCCCATGCTGCCAAAGGATACCATACTTGCAGAGCTCCTTCAGATACATAAAGAAC
ACATTGTAGGATACCATGAACATGATTCTCTTTTGGACCACAAAGAAGAAGAAGAGTTGACTGAAGAAGAAAGAAAAGCAGCTTGGGCTG
AGTATGAAGCAGAGAAGAAGGGACTGACCATGCGTTTCAACATACCAACTGGGACCAATTTACCCCCTGTCAGTTTCAACTCTCAAACTC
CTTATATTCCTTTCAATTTGGGAGCCCTGTCAGCAATGAGTAATCAACAGCTGGAGGACCTCATTAATCAAGGAAGAGAAAAAGTTGTAG
AAGCAACAAACAGTGTGACAGCAGTGAGGATTCAACCTCTTGAGGATATAATTTCAGCTGTATGGAAGGAGAACATGAATCTCTCAGAGG
CCCAAGTACAGGCGTTAGCATTAAGTAGACAAGCCAGCCAGGAGCTTGATGTTAAACGAAGAGAAGCAATCTACAATGATGTATTGACAA
AACAACAGATGTCTGAACAAGTGTCGGAGGCCGAGTTACTCCCACAGCTGAGCAGAGCCCCATCCCAGGCTGCAGAAAGTAGTCCAGCAA
AGAAGGATGTACTGTATTCTCAGCCACCATCAAAGCCCATTCGTAGGAAATTCAGACCAGAAAACCAAGCTACAGAAAACCAAGAGCCTT
CCACTGCTGCAAGTGGGCCAGCTTCTGCGGCAACCATGAAACCGCATCCAACAGTCCAAAAGCAGTCTTCCAAACAGAAGAAGGCCATTC
AAACTGCTATCCGCAAAAATAAAGAGGCAAACGCAGTGCTGGCTCGGCTGAACAGTGAGCTCCAGCAGCAGCTCAAGGAGGTTCATCAAG
AACGAATTGCATTGGAAAACCAATTGGAACAACTTCGTCCGGTCACTGTGTTGTGACCCCCCCATGGTTCAAGTGACAGTGGGTGACCTT
GTCTGCCAAGATCTTTCTTTTGAATGTTTTGAACCCAACTACTTGTCATAGATGTTTGACTGTGTCAAAAGCTGTGAGCAGCAAAATATA

>8359_8359_6_ATRX-REPS2_ATRX_chrX_76776266_ENST00000395603_REPS2_chrX_17151947_ENST00000380064_length(amino acids)=2496AA_BP=2362
MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYV
ESDDEKPLDDETVNEDASNENSENDITMQSLPKEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDE
QCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKV
YEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSV
LADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKS
TGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKT
TAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPT
ETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIH
TNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFD
SSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRK
VAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHF
PKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK
EDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI
EDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEE
GKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESG
VSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK
KIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGV
QFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELAT
VKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTG
TPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVR
MTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYT
KKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSG
KMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNV
RGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERH
FTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMR
FNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQA
SQELDVKRREAIYNDVLTKQQMSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT

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Fusion Gene PPI Analysis for ATRX-REPS2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34351189_13262400.02493.0DAXX
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33341189_13262362.02455.0DAXX
HgeneATRXchrX:76776266chrX:17151947ENST00000373344-34352010_22802400.02493.0MECP2
HgeneATRXchrX:76776266chrX:17151947ENST00000395603-33342010_22802362.02455.0MECP2
TgeneREPS2chrX:76776266chrX:17151947ENST000003038431318561_660525.0660.0ASAP1
TgeneREPS2chrX:76776266chrX:17151947ENST000003572771318561_660526.0661.0ASAP1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneREPS2chrX:76776266chrX:17151947ENST000003038431318514_660525.0660.0RALBP1
TgeneREPS2chrX:76776266chrX:17151947ENST000003572771318514_660526.0661.0RALBP1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATRX-REPS2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATRX-REPS2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource