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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SLCO2B1-HNF4A (FusionGDB2 ID:83599)

Fusion Gene Summary for SLCO2B1-HNF4A

Fusion gene summary

Fusion gene information	Fusion gene name: SLCO2B1-HNF4A
	Fusion gene ID: 83599
		Hgene	Tgene
	Gene symbol	SLCO2B1	HNF4A
	Gene ID	11309	6927
	Gene name	solute carrier organic anion transporter family member 2B1	HNF1 homeobox A
	Synonyms	OATP-B\|OATP2B1\|OATPB\|SLC21A9	HNF-1A\|HNF1\|HNF4A\|IDDM20\|LFB1\|MODY3\|TCF-1\|TCF1
	Cytomap	11q13.4	12q24.31
	Type of gene	protein-coding	protein-coding
	Description	solute carrier organic anion transporter family member 2B1OATP-RP2organic anion transporter Borganic anion transporter polypeptide-related protein 2solute carrier family 21 (organic anion transporter), member 9	hepatocyte nuclear factor 1-alphaHNF-1-alphaalbumin proximal factorhepatic nuclear factor 1interferon production regulator factorliver-specific transcription factor LF-B1transcription factor 1, hepatictruncated hepatocyte nuclear factor 1 alpha
	Modification date	20200315	20200313
	UniProtAcc	.	P41235
	Ensembl transtripts involved in fusion gene	ENST00000341411, ENST00000428359, ENST00000454962, ENST00000532236, ENST00000289575, ENST00000525650, ENST00000531756, ENST00000526660,	ENST00000316099, ENST00000316673, ENST00000415691, ENST00000443598, ENST00000457232, ENST00000609795,
Fusion gene scores	* DoF score	4 X 6 X 4=96	6 X 6 X 5=180
	# samples	5	7
	** MAII score	log2(5/96*10)=-0.941106310946431 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(7/180*10)=-1.36257007938471 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SLCO2B1 [Title/Abstract] AND HNF4A [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SLCO2B1(74870917)-HNF4A(43034698), # samples:2 SLCO2B1(74870917)-HNF4A(43031194), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	SLCO2B1	GO:0015711	organic anion transport	12724351\|22021325
Hgene	SLCO2B1	GO:0055085	transmembrane transport	12724351\|29871943
Tgene	HNF4A	GO:0001779	natural killer cell differentiation	11301190
Tgene	HNF4A	GO:0006357	regulation of transcription by RNA polymerase II	10330009
Tgene	HNF4A	GO:0045893	positive regulation of transcription, DNA-templated	1989880\|11980910\|12453420

Fusion gene breakpoints across SLCO2B1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across HNF4A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	KIRC	TCGA-AS-3777-01A	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
ChimerDB4	KIRC	TCGA-AS-3777-01A	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
ChimerDB4	KIRC	TCGA-AS-3777-01A	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
ChimerDB4	LIHC	TCGA-DD-A115-01A	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
ChimerDB4	LIHC	TCGA-DD-A115-01A	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+

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Fusion Gene ORF analysis for SLCO2B1-HNF4A

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5UTR-3CDS	ENST00000341411	ENST00000316099	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000341411	ENST00000316673	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000341411	ENST00000415691	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000341411	ENST00000443598	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000341411	ENST00000457232	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000341411	ENST00000609795	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000316099	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000316673	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000415691	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000443598	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000457232	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000428359	ENST00000609795	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000454962	ENST00000316099	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000454962	ENST00000316673	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000454962	ENST00000415691	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000454962	ENST00000443598	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000454962	ENST00000457232	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000454962	ENST00000609795	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000532236	ENST00000316099	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000532236	ENST00000316673	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000532236	ENST00000415691	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000532236	ENST00000443598	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000532236	ENST00000457232	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-3CDS	ENST00000532236	ENST00000609795	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
5UTR-intron	ENST00000428359	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
5UTR-intron	ENST00000428359	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
5UTR-intron	ENST00000428359	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
5UTR-intron	ENST00000428359	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
5UTR-intron	ENST00000428359	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
5UTR-intron	ENST00000428359	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
In-frame	ENST00000289575	ENST00000316099	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000289575	ENST00000316673	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000289575	ENST00000415691	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000289575	ENST00000443598	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000289575	ENST00000457232	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000289575	ENST00000609795	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000525650	ENST00000316099	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000525650	ENST00000316673	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000525650	ENST00000415691	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000525650	ENST00000443598	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000525650	ENST00000457232	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000525650	ENST00000609795	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000531756	ENST00000316099	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000531756	ENST00000316673	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000531756	ENST00000415691	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000531756	ENST00000443598	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000531756	ENST00000457232	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
In-frame	ENST00000531756	ENST00000609795	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000316099	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000316673	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000415691	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000443598	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000457232	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000289575	ENST00000609795	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000316099	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000316673	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000415691	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000443598	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000457232	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000341411	ENST00000609795	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000428359	ENST00000316099	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000428359	ENST00000316673	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000428359	ENST00000415691	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000428359	ENST00000443598	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000428359	ENST00000457232	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000428359	ENST00000609795	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000316099	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000316673	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000415691	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000443598	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000457232	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000454962	ENST00000609795	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000316099	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000316673	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000415691	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000443598	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000457232	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000525650	ENST00000609795	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000316099	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000316099	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000316673	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000316673	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000415691	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000415691	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000443598	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000443598	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000457232	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000457232	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000609795	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000526660	ENST00000609795	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000316099	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000316673	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000415691	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000443598	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000457232	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000531756	ENST00000609795	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000316099	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000316673	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000415691	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000443598	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000457232	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43034698	+
intron-3CDS	ENST00000532236	ENST00000609795	SLCO2B1	chr11	74870949	-	HNF4A	chr20	43034698	+
intron-intron	ENST00000289575	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000289575	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000289575	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000289575	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000289575	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000289575	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000341411	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000341411	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000341411	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000341411	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000341411	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000341411	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000454962	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000454962	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000454962	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000454962	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000454962	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000454962	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000525650	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000525650	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000525650	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000525650	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000525650	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000525650	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000526660	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000526660	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000526660	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000526660	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000526660	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000526660	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000531756	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000531756	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000531756	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000531756	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000531756	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000531756	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000532236	ENST00000316099	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000532236	ENST00000316673	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000532236	ENST00000415691	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000532236	ENST00000443598	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000532236	ENST00000457232	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+
intron-intron	ENST00000532236	ENST00000609795	SLCO2B1	chr11	74870917	+	HNF4A	chr20	43031194	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000289575	SLCO2B1	chr11	74862442	-	ENST00000316673	HNF4A	chr20	43034698	+	1727	411	395	1720	441
ENST00000289575	SLCO2B1	chr11	74862442	-	ENST00000609795	HNF4A	chr20	43034698	+	1550	411	395	1549	385
ENST00000289575	SLCO2B1	chr11	74862442	-	ENST00000457232	HNF4A	chr20	43034698	+	1697	411	395	1690	431
ENST00000289575	SLCO2B1	chr11	74862442	-	ENST00000443598	HNF4A	chr20	43034698	+	1810	411	395	1549	384
ENST00000289575	SLCO2B1	chr11	74862442	-	ENST00000316099	HNF4A	chr20	43034698	+	4901	411	395	1720	441
ENST00000289575	SLCO2B1	chr11	74862442	-	ENST00000415691	HNF4A	chr20	43034698	+	2526	411	395	1690	431
ENST00000531756	SLCO2B1	chr11	74862442	-	ENST00000316673	HNF4A	chr20	43034698	+	1644	328	312	1637	441
ENST00000531756	SLCO2B1	chr11	74862442	-	ENST00000609795	HNF4A	chr20	43034698	+	1467	328	312	1466	384
ENST00000531756	SLCO2B1	chr11	74862442	-	ENST00000457232	HNF4A	chr20	43034698	+	1614	328	312	1607	431
ENST00000531756	SLCO2B1	chr11	74862442	-	ENST00000443598	HNF4A	chr20	43034698	+	1727	328	312	1466	384
ENST00000531756	SLCO2B1	chr11	74862442	-	ENST00000316099	HNF4A	chr20	43034698	+	4818	328	312	1637	441
ENST00000531756	SLCO2B1	chr11	74862442	-	ENST00000415691	HNF4A	chr20	43034698	+	2443	328	312	1607	431
ENST00000525650	SLCO2B1	chr11	74862442	-	ENST00000316673	HNF4A	chr20	43034698	+	1599	283	267	1592	441
ENST00000525650	SLCO2B1	chr11	74862442	-	ENST00000609795	HNF4A	chr20	43034698	+	1422	283	267	1421	384
ENST00000525650	SLCO2B1	chr11	74862442	-	ENST00000457232	HNF4A	chr20	43034698	+	1569	283	267	1562	431
ENST00000525650	SLCO2B1	chr11	74862442	-	ENST00000443598	HNF4A	chr20	43034698	+	1682	283	267	1421	384
ENST00000525650	SLCO2B1	chr11	74862442	-	ENST00000316099	HNF4A	chr20	43034698	+	4773	283	267	1592	441
ENST00000525650	SLCO2B1	chr11	74862442	-	ENST00000415691	HNF4A	chr20	43034698	+	2398	283	267	1562	431

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000289575	ENST00000316673	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.030154996	0.96984494
ENST00000289575	ENST00000609795	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.030195089	0.96980494
ENST00000289575	ENST00000457232	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.019652743	0.9803473
ENST00000289575	ENST00000443598	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.02650347	0.97349656
ENST00000289575	ENST00000316099	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.011370791	0.9886292
ENST00000289575	ENST00000415691	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.020194491	0.9798055
ENST00000531756	ENST00000316673	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.026030516	0.97396946
ENST00000531756	ENST00000609795	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.030127022	0.969873
ENST00000531756	ENST00000457232	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.016382765	0.9836172
ENST00000531756	ENST00000443598	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.025146233	0.97485375
ENST00000531756	ENST00000316099	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.01106691	0.9889331
ENST00000531756	ENST00000415691	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.018751396	0.9812486
ENST00000525650	ENST00000316673	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.021660523	0.97833943
ENST00000525650	ENST00000609795	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.027616587	0.97238344
ENST00000525650	ENST00000457232	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.013783213	0.9862168
ENST00000525650	ENST00000443598	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.022602687	0.97739726
ENST00000525650	ENST00000316099	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.010889218	0.98911077
ENST00000525650	ENST00000415691	SLCO2B1	chr11	74862442	-	HNF4A	chr20	43034698	+	0.017186083	0.98281395

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Fusion Genomic Features for SLCO2B1-HNF4A

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SLCO2B1-HNF4A

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:74870917/chr20:43034698)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	HNF4A P41235
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (PubMed:30597922). Activates the transcription of CYP2C38 (By similarity). Represses the CLOCK-ARNTL/BMAL1 transcriptional activity and is essential for circadian rhythm maintenance and period regulation in the liver and colon cells (PubMed:30530698). {ECO:0000250\|UniProtKB:P49698, ECO:0000269\|PubMed:30530698, ECO:0000269\|PubMed:30597922}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000316099

57_132

475.0

DNA binding

Nuclear receptor

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000316673

57_132

453.0

DNA binding

Nuclear receptor

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000415691

57_132

465.0

DNA binding

Nuclear receptor

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000443598

57_132

418.0

DNA binding

Nuclear receptor

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000457232

57_132

443.0

DNA binding

Nuclear receptor

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000316099

147_377

475.0

Domain

NR LBD

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000316673

147_377

453.0

Domain

NR LBD

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000415691

147_377

465.0

Domain

NR LBD

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000443598

147_377

418.0

Domain

NR LBD

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000457232

147_377

443.0

Domain

NR LBD

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000316099

368_376

475.0

Motif

9aaTAD

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000316673

368_376

453.0

Motif

9aaTAD

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000415691

368_376

465.0

Motif

9aaTAD

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000443598

368_376

418.0

Motif

9aaTAD

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000457232

368_376

443.0

Motif

9aaTAD

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000316099

60_80

475.0

Zinc finger

NR C4-type

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000316099

96_120

475.0

Zinc finger

NR C4-type

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000316673

60_80

453.0

Zinc finger

NR C4-type

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000316673

96_120

453.0

Zinc finger

NR C4-type

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000415691

60_80

465.0

Zinc finger

NR C4-type

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000415691

96_120

465.0

Zinc finger

NR C4-type

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000443598

60_80

418.0

Zinc finger

NR C4-type

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000443598

96_120

418.0

Zinc finger

NR C4-type

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000457232

60_80

443.0

Zinc finger

NR C4-type

Tgene

HNF4A

chr11:74862442

chr20:43034698

ENST00000457232

96_120

443.0

Zinc finger

NR C4-type

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

483_543

710.0

Domain

Kazal-like

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

483_543

483.0

Domain

Kazal-like

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

483_543

483.0

Domain

Kazal-like

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

110_115

710.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

141_185

710.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

1_49

710.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

216_234

710.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

256_273

710.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

299_366

710.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

389_408

710.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

433_436

710.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

461_564

710.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

588_596

710.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

623_655

710.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

674_709

710.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

70_88

710.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

110_115

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

141_185

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

1_49

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

216_234

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

256_273

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

299_366

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

389_408

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

433_436

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

461_564

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

588_596

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

623_655

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

674_709

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

70_88

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

110_115

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

141_185

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

1_49

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

216_234

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

256_273

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

299_366

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

389_408

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

433_436

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

461_564

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

588_596

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

623_655

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

674_709

483.0

Topological domain

Cytoplasmic

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

70_88

483.0

Topological domain

Extracellular

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

116_140

710.0

Transmembrane

Helical%3B Name%3D3

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

186_215

710.0

Transmembrane

Helical%3B Name%3D4

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

235_255

710.0

Transmembrane

Helical%3B Name%3D5

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

274_298

710.0

Transmembrane

Helical%3B Name%3D6

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

367_388

710.0

Transmembrane

Helical%3B Name%3D7

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

409_432

710.0

Transmembrane

Helical%3B Name%3D8

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

437_460

710.0

Transmembrane

Helical%3B Name%3D9

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

50_69

710.0

Transmembrane

Helical%3B Name%3D1

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

565_587

710.0

Transmembrane

Helical%3B Name%3D10

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

597_622

710.0

Transmembrane

Helical%3B Name%3D11

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

656_673

710.0

Transmembrane

Helical%3B Name%3D12

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000289575

89_109

710.0

Transmembrane

Helical%3B Name%3D2

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

116_140

483.0

Transmembrane

Helical%3B Name%3D3

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

186_215

483.0

Transmembrane

Helical%3B Name%3D4

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

235_255

483.0

Transmembrane

Helical%3B Name%3D5

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

274_298

483.0

Transmembrane

Helical%3B Name%3D6

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

367_388

483.0

Transmembrane

Helical%3B Name%3D7

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

409_432

483.0

Transmembrane

Helical%3B Name%3D8

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

437_460

483.0

Transmembrane

Helical%3B Name%3D9

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

50_69

483.0

Transmembrane

Helical%3B Name%3D1

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

565_587

483.0

Transmembrane

Helical%3B Name%3D10

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

597_622

483.0

Transmembrane

Helical%3B Name%3D11

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

656_673

483.0

Transmembrane

Helical%3B Name%3D12

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000341411

89_109

483.0

Transmembrane

Helical%3B Name%3D2

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

116_140

483.0

Transmembrane

Helical%3B Name%3D3

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

186_215

483.0

Transmembrane

Helical%3B Name%3D4

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

235_255

483.0

Transmembrane

Helical%3B Name%3D5

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

274_298

483.0

Transmembrane

Helical%3B Name%3D6

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

367_388

483.0

Transmembrane

Helical%3B Name%3D7

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

409_432

483.0

Transmembrane

Helical%3B Name%3D8

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

437_460

483.0

Transmembrane

Helical%3B Name%3D9

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

50_69

483.0

Transmembrane

Helical%3B Name%3D1

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

565_587

483.0

Transmembrane

Helical%3B Name%3D10

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

597_622

483.0

Transmembrane

Helical%3B Name%3D11

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

656_673

483.0

Transmembrane

Helical%3B Name%3D12

Hgene

SLCO2B1

chr11:74862442

chr20:43034698

ENST00000454962

89_109

483.0

Transmembrane

Helical%3B Name%3D2

Top

Fusion Gene Sequence for SLCO2B1-HNF4A

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>83599_83599_1_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000316099_length(transcript)=4901nt_BP=411nt
AAAAGGACAGGCTGAGGCTGAGCCTCAGGGAGGCGGGGTGCAGCTTCCTCTTCACAGAGAGGCTGGACTTGAACAAACCCAGCCTTCTAT
ACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGC
AAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGC
ATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTA
AATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCA
ACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGG
GCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGT
GCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGT
CAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGA
TCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGG
CCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAG
CCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGA
GCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCA
TCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACT
ACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGA
TCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCCAGCGATG
CACCCCATGCCCACCACCCCCTGCACCCTCACCTGATGCAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCCACTCACC
TCAGCAACGGACAGATGTGTGAGTGGCCCCGACCCAGGGGACAGGCAGCCACCCCTGAGACCCCACAGCCCTCACCGCCAGGTGGCTCAG
GGTCTGAGCCCTATAAGCTCCTGCCGGGAGCCGTCGCCACAATCGTCAAGCCCCTCTCTGCCATCCCCCAGCCGACCATCACCAAGCAGG
AAGTTATCTAGCAAGCCGCTGGGGCTTGGGGGCTCCACTGGCTCCCCCCAGCCCCCTAAGAGAGCACCTGGTGATCACGTGGTCACGGCA
AAGGAAGACGTGATGCCAGGACCAGTCCCAGAGCAGGAATGGGAAGGATGAAGGGCCCGAGAACATGGCCTAAGGGCCACATCCCACTGC
CACCCTTGACGCCCTGCTCTGGATAACAAGACTTTGACTTGGGGAGACCTCTACTGCCTTGGACAACTTTTCTCATGTTGAAGCCACTGC
CTTCACCTTCACCTTCATCCATGTCCAACCCCCGACTTCATCCCAAAGGACAGCCGCCTGGAGATGACTTGAGGCCTTACTTAAACCCAG
CTCCCTTCTTCCCTAGCCTGGTGCTTCTCCTCTCCTAGCCCCTGTCATGGTGTCCAGACAGAGCCCTGTGAGGCTGGGTCCAATTGTGGC
ACTTGGGGCACCTTGCTCCTCCTTCTGCTGCTGCCCCCACCTCTGCTGCCTCCCTCTGCTGTCACCTTGCTCAGCCATCCCGTCTTCTCC
AACACCACCTCTCCAGAGGCCAAGGAGGCCTTGGAAACGATTCCCCCAGTCATTCTGGGAACATGTTGTAAGCACTGACTGGGACCAGGC
ACCAGGCAGGGTCTAGAAGGCTGTGGTGAGGGAAGACGCCTTTCTCCTCCAACCCAACCTCATCCTCCTTCTTCAGGGACTTGGGTGGGT
ACTTGGGTGAGGATCCCTGAAGGCCTTCAACCCGAGAAAACAAACCCAGGTTGGCGACTGCAACAGGAACTTGGAGTGGAGAGGAAAAGC
ATCAGAAAGAGGCAGACCATCCACCAGGCCTTTGAGAAAGGGTAGAATTCTGGCTGGTAGAGCAGGTGAGATGGGACATTCCAAAGAACA
GCCTGAGCCAAGGCCTAGTGGTAGTAAGAATCTAGCAAGAATTGAGGAAGAATGGTGTGGGAGAGGGATGATGAAGAGAGAGAGGGCCTG
CTGGAGAGCATAGGGTCTGGAACACCAGGCTGAGGTCCTGATCAGCTTCAAGGAGTATGCAGGGAGCTGGGCTTCCAGAAAATGAACACA
GCAGTTCTGCAGAGGACGGGAGGCTGGAAGCTGGGAGGTCAGGTGGGGTGGATGATATAATGCGGGTGAGAGTAATGAGGCTTGGGGCTG
GAGAGGACAAGATGGGTAAACCCTCACATCAGAGTGACATCCAGGAGGAATAAGCTCCCAGGGCCTGTCTCAAGCTCTTCCTTACTCCCA
GGCACTGTCTTAAGGCATCTGACATGCATCATCTCATTTAATCCTCCCTTCCTCCCTATTAACCTAGAGATTGTTTTTGTTTTTTATTCT
CCTCCTCCCTCCCCGCCCTCACCCGCCCCACTCCCTCCTAACCTAGAGATTGTTACAGAAGCTGAAATTGCGTTCTAAGAGGTGAAGTGA
TTTTTTTTCTGAAACTCACACAACTAGGAAGTGGCTGAGTCAGGACTTGAACCCAGGTCTCCCTGGATCAGAACAGGAGCTCTTAACTAC
AGTGGCTGAATAGCTTCTCCAAAGGCTCCCTGTGTTCTCACCGTGATCAAGTTGAGGGGCTTCCGGCTCCCTTCTACAGCCTCAGAAACC
AGACTCGTTCTTCTGGGAACCCTGCCCACTCCCAGGACCAAGATTGGCCTGAGGCTGCACTAAAATTCACTTAGGGTCGAGCATCCTGTT
TGCTGATAAATATTAAGGAGAATTCATGACTCTTGACAGCTTTTCTCTCTTCACTCCCCAAGTCAAGGGGAGGGGTGGCAGGGGTCTGTT
TCCTGGAAGTCAGGCTCATCTGGCCTGTTGGCATGGGGGTGGGACAGTGTGCACAGTGTGGGGGCAGGGGAGGGCTAAGCAGGCCTGGGT
TTGAGGGCTGCTCCGGAGACCGTCACTCCAGGTGCATTCTGGAAGCATTAGACCCCAGGATGGAGCGACCAGCATGTCATCCATGTGGAA
TCTTGGTGGCTTTGAGGACATTCTGGAAAATGCCACTGACCAGTGTGAACAAAAGGGATGTGTTATGGGGCTGGAGGTGTGATTAGGTAG
GAGGGAAACTGTTGGACCGACTCCTGCCCCCTGCTCAACACTGACCCCTCTGAGTGGTTGGAGGCAGTGCCCCAGTGCCCAGAAATCCCA
CCATTAGTGATTGTTTTTTATGAGAAAGAGGCGTGGAGAAGTATTGGGGCAATGTGTCAGGGAGGAATCACCACATCCCTACGGCAGTCC
CAGCCAAGCCCCCAATCCCAGCGGAGACTGTGCCCTGCTCAGAGCTCCCAAGCCTTCCCCCACCACCTCACTCAAGTGCCCCTGAAATCC
CTGCCAGACGGCTCAGCCTGGTCTGCGGTAAGGCAGGGAGGCTGGAACCATTTCTGGGCATTGTGGTCATTCCCACTGTGTTCCTCCACC
TCCTCCCTCCAGCGTTGCTCAGACCTCTGTCTTGGGAGAAAGGTTGAGATAAGAATGTCCCATGGAGTGCCGTGGGCAACAGTGGCCCTT
CATGGGAACAATCTGTTGGAGCAGGGGGTCAGTTCTCTGCTGGGAATCTACCCCTTTCTGGAGGAGAAACCCATTCCACCTTAATAACTT
TATTGTAATGTGAGAAACACAAAACAAAGTTTACTTTTTTGACTCTAAGCTGACATGATATTAGAAAATCTCTCGCTCTCTTTTTTTTTT
TTTTTTTTTTTTTTGGCTACTTGAGTTGTGGTCCTAAAACATAAAATCTGATGGACAAACAGAGGGTTGCTGGGGGGACAAGCGTGGGCA
CAATTTCCCCACCAAGACACCCTGATCTTCAGGCGGGTCTCAGGAGCTTCTAAAAATCCGCATGGCTCTCCTGAGAGTGGACAGAGGAGA
GGAGAGGGTCAGAAATGAACGCTCTTCTATTTCTTGTCATTACCAAGCCAATTACTTTTGCCAAATTTTTCTGTGATCTGCCCTGATTAA
GATGAATTGTGAAATTTACATCAAGCAATTATCAAAGCGGGCTGGGTCCCATCAGAACGACCCACATCTTTCTGTGGGTGTGAATGTCAT
TAGGTCTTGCGCTGACCCCTGAGCCCCCATCACTGCCGCCTGATGGGGCAAAGAAACAAAAAACATTTCTTACTCTTCTGTGTTTTAACA

>83599_83599_1_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000316099_length(amino acids)=441AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_2_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000316673_length(transcript)=1727nt_BP=411nt
AAAAGGACAGGCTGAGGCTGAGCCTCAGGGAGGCGGGGTGCAGCTTCCTCTTCACAGAGAGGCTGGACTTGAACAAACCCAGCCTTCTAT
ACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGC
AAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGC
ATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTA
AATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCA
ACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGG
GCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGT
GCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGT
CAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGA
TCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGG
CCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAG
CCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGA
GCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCA
TCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACT
ACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGA
TCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCCAGCGATG
CACCCCATGCCCACCACCCCCTGCACCCTCACCTGATGCAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCCACTCACC
TCAGCAACGGACAGATGTGTGAGTGGCCCCGACCCAGGGGACAGGCAGCCACCCCTGAGACCCCACAGCCCTCACCGCCAGGTGGCTCAG
GGTCTGAGCCCTATAAGCTCCTGCCGGGAGCCGTCGCCACAATCGTCAAGCCCCTCTCTGCCATCCCCCAGCCGACCATCACCAAGCAGG

>83599_83599_2_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000316673_length(amino acids)=441AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_3_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000415691_length(transcript)=2526nt_BP=411nt
AAAAGGACAGGCTGAGGCTGAGCCTCAGGGAGGCGGGGTGCAGCTTCCTCTTCACAGAGAGGCTGGACTTGAACAAACCCAGCCTTCTAT
ACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGC
AAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGC
ATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTA
AATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCA
ACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGG
GCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGT
GCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGT
CAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGA
TCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGG
CCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAG
CCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGA
GCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCA
TCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACT
ACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGA
TCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCCAGCGATG
CACCCCATGCCCACCACCCCCTGCACCCTCACCTGATGCAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCCACTCACC
TCAGCAACGGACAGATGTCCACCCCTGAGACCCCACAGCCCTCACCGCCAGGTGGCTCAGGGTCTGAGCCCTATAAGCTCCTGCCGGGAG
CCGTCGCCACAATCGTCAAGCCCCTCTCTGCCATCCCCCAGCCGACCATCACCAAGCAGGAAGTTATCTAGCAAGCCGCTGGGGCTTGGG
GGCTCCACTGGCTCCCCCCAGCCCCCTAAGAGAGCACCTGGTGATCACGTGGTCACGGCAAAGGAAGACGTGATGCCAGGACCAGTCCCA
GAGCAGGAATGGGAAGGATGAAGGGCCCGAGAACATGGCCTAAGGGCCACATCCCACTGCCACCCTTGACGCCCTGCTCTGGATAACAAG
ACTTTGACTTGGGGAGACCTCTACTGCCTTGGACAACTTTTCTCATGTTGAAGCCACTGCCTTCACCTTCACCTTCATCCATGTCCAACC
CCCGACTTCATCCCAAAGGACAGCCGCCTGGAGATGACTTGAGGCCTTACTTAAACCCAGCTCCCTTCTTCCCTAGCCTGGTGCTTCTCC
TCTCCTAGCCCCTGTCATGGTGTCCAGACAGAGCCCTGTGAGGCTGGGTCCAATTGTGGCACTTGGGGCACCTTGCTCCTCCTTCTGCTG
CTGCCCCCACCTCTGCTGCCTCCCTCTGCTGTCACCTTGCTCAGCCATCCCGTCTTCTCCAACACCACCTCTCCAGAGGCCAAGGAGGCC
TTGGAAACGATTCCCCCAGTCATTCTGGGAACATGTTGTAAGCACTGACTGGGACCAGGCACCAGGCAGGGTCTAGAAGGCTGTGGTGAG
GGAAGACGCCTTTCTCCTCCAACCCAACCTCATCCTCCTTCTTCAGGGACTTGGGTGGGTACTTGGGTGAGGATCCCTGAAGGCCTTCAA
CCCGAGAAAACAAACCCAGGTTGGCGACTGCAACAGGAACTTGGAGTGGAGAGGAAAAGCATCAGAAAGAGGCAGACCATCCACCAGGCC

>83599_83599_3_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000415691_length(amino acids)=431AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_4_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000443598_length(transcript)=1810nt_BP=411nt
AAAAGGACAGGCTGAGGCTGAGCCTCAGGGAGGCGGGGTGCAGCTTCCTCTTCACAGAGAGGCTGGACTTGAACAAACCCAGCCTTCTAT
ACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGC
AAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGC
ATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTA
AATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCA
ACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGG
GCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGT
GCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGT
CAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGA
TCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGG
CCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAG
CCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGA
GCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCA
TCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACT
ACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGA
TCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGTCCGTGCCAAGCCC
AGGAGGGGCGGGGTTGGAGTGGGGACTCCCCAGGAGACAGGCCTCACACAGTGAGCTCACCCCTCAGCTCCTTGGCTTCCCCACTGTGCC
GCTTTGGGCAAGTTGCTTAACCTGTCTGTGCCTCAGTTTCCTCACCAGAAAAATGGGAACAAGGCAATGGTCTATTTGTTCAGGCACCGA
GAACCTAGCACGTGCCAGTCACTGTTCTAAGTGCTGGCAATTCAGCAAAGAACAAGATCTTTGCCCTCGGGGAGGCTGTGTGTGTGTGAG
TATGTATGGATGCGTGGATATCTGTGTATATGCCCGTATGTGCGTGCATGTGTATATAAAGCCTCACATTTTATGATTTTGAAATAAACA

>83599_83599_4_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000443598_length(amino acids)=384AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGPCQAQEGRGWSGDSPG

--------------------------------------------------------------
>83599_83599_5_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000457232_length(transcript)=1697nt_BP=411nt
AAAAGGACAGGCTGAGGCTGAGCCTCAGGGAGGCGGGGTGCAGCTTCCTCTTCACAGAGAGGCTGGACTTGAACAAACCCAGCCTTCTAT
ACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGC
AAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGC
ATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTA
AATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCA
ACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGG
GCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGT
GCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGT
CAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGA
TCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGG
CCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAG
CCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGA
GCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCA
TCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACT
ACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGA
TCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCCAGCGATG
CACCCCATGCCCACCACCCCCTGCACCCTCACCTGATGCAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCCACTCACC
TCAGCAACGGACAGATGTCCACCCCTGAGACCCCACAGCCCTCACCGCCAGGTGGCTCAGGGTCTGAGCCCTATAAGCTCCTGCCGGGAG

>83599_83599_5_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000457232_length(amino acids)=431AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_6_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000609795_length(transcript)=1550nt_BP=411nt
AAAAGGACAGGCTGAGGCTGAGCCTCAGGGAGGCGGGGTGCAGCTTCCTCTTCACAGAGAGGCTGGACTTGAACAAACCCAGCCTTCTAT
ACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGC
AAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGC
ATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTA
AATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCA
ACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGG
GCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGT
GCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGT
CAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGA
TCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGG
CCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAG
CCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGA
GCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCA
TCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACT
ACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGA
TCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGTCCGTGCCAAGCCC
AGGAGGGGCGGGGTTGGAGTGGGGACTCCCCAGGAGACAGGCCTCACACAGTGAGCTCACCCCTCAGCTCCTTGGCTTCCCCACTGTGCC

>83599_83599_6_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000289575_HNF4A_chr20_43034698_ENST00000609795_length(amino acids)=385AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGPCQAQEGRGWSGDSPG

--------------------------------------------------------------
>83599_83599_7_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000316099_length(transcript)=4773nt_BP=283nt
CAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCC
TGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGC
CCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATG
GGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGG
GACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTAC
TCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGC
ATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCG
CTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATC
GCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGAC
GACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTC
CTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTG
CCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGAT
CCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTT
GGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCC
AAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCCAGCGATGCACCCCATGCCCACCACCCCCTGCACCCTCACCTGATG
CAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCCACTCACCTCAGCAACGGACAGATGTGTGAGTGGCCCCGACCCAGG
GGACAGGCAGCCACCCCTGAGACCCCACAGCCCTCACCGCCAGGTGGCTCAGGGTCTGAGCCCTATAAGCTCCTGCCGGGAGCCGTCGCC
ACAATCGTCAAGCCCCTCTCTGCCATCCCCCAGCCGACCATCACCAAGCAGGAAGTTATCTAGCAAGCCGCTGGGGCTTGGGGGCTCCAC
TGGCTCCCCCCAGCCCCCTAAGAGAGCACCTGGTGATCACGTGGTCACGGCAAAGGAAGACGTGATGCCAGGACCAGTCCCAGAGCAGGA
ATGGGAAGGATGAAGGGCCCGAGAACATGGCCTAAGGGCCACATCCCACTGCCACCCTTGACGCCCTGCTCTGGATAACAAGACTTTGAC
TTGGGGAGACCTCTACTGCCTTGGACAACTTTTCTCATGTTGAAGCCACTGCCTTCACCTTCACCTTCATCCATGTCCAACCCCCGACTT
CATCCCAAAGGACAGCCGCCTGGAGATGACTTGAGGCCTTACTTAAACCCAGCTCCCTTCTTCCCTAGCCTGGTGCTTCTCCTCTCCTAG
CCCCTGTCATGGTGTCCAGACAGAGCCCTGTGAGGCTGGGTCCAATTGTGGCACTTGGGGCACCTTGCTCCTCCTTCTGCTGCTGCCCCC
ACCTCTGCTGCCTCCCTCTGCTGTCACCTTGCTCAGCCATCCCGTCTTCTCCAACACCACCTCTCCAGAGGCCAAGGAGGCCTTGGAAAC
GATTCCCCCAGTCATTCTGGGAACATGTTGTAAGCACTGACTGGGACCAGGCACCAGGCAGGGTCTAGAAGGCTGTGGTGAGGGAAGACG
CCTTTCTCCTCCAACCCAACCTCATCCTCCTTCTTCAGGGACTTGGGTGGGTACTTGGGTGAGGATCCCTGAAGGCCTTCAACCCGAGAA
AACAAACCCAGGTTGGCGACTGCAACAGGAACTTGGAGTGGAGAGGAAAAGCATCAGAAAGAGGCAGACCATCCACCAGGCCTTTGAGAA
AGGGTAGAATTCTGGCTGGTAGAGCAGGTGAGATGGGACATTCCAAAGAACAGCCTGAGCCAAGGCCTAGTGGTAGTAAGAATCTAGCAA
GAATTGAGGAAGAATGGTGTGGGAGAGGGATGATGAAGAGAGAGAGGGCCTGCTGGAGAGCATAGGGTCTGGAACACCAGGCTGAGGTCC
TGATCAGCTTCAAGGAGTATGCAGGGAGCTGGGCTTCCAGAAAATGAACACAGCAGTTCTGCAGAGGACGGGAGGCTGGAAGCTGGGAGG
TCAGGTGGGGTGGATGATATAATGCGGGTGAGAGTAATGAGGCTTGGGGCTGGAGAGGACAAGATGGGTAAACCCTCACATCAGAGTGAC
ATCCAGGAGGAATAAGCTCCCAGGGCCTGTCTCAAGCTCTTCCTTACTCCCAGGCACTGTCTTAAGGCATCTGACATGCATCATCTCATT
TAATCCTCCCTTCCTCCCTATTAACCTAGAGATTGTTTTTGTTTTTTATTCTCCTCCTCCCTCCCCGCCCTCACCCGCCCCACTCCCTCC
TAACCTAGAGATTGTTACAGAAGCTGAAATTGCGTTCTAAGAGGTGAAGTGATTTTTTTTCTGAAACTCACACAACTAGGAAGTGGCTGA
GTCAGGACTTGAACCCAGGTCTCCCTGGATCAGAACAGGAGCTCTTAACTACAGTGGCTGAATAGCTTCTCCAAAGGCTCCCTGTGTTCT
CACCGTGATCAAGTTGAGGGGCTTCCGGCTCCCTTCTACAGCCTCAGAAACCAGACTCGTTCTTCTGGGAACCCTGCCCACTCCCAGGAC
CAAGATTGGCCTGAGGCTGCACTAAAATTCACTTAGGGTCGAGCATCCTGTTTGCTGATAAATATTAAGGAGAATTCATGACTCTTGACA
GCTTTTCTCTCTTCACTCCCCAAGTCAAGGGGAGGGGTGGCAGGGGTCTGTTTCCTGGAAGTCAGGCTCATCTGGCCTGTTGGCATGGGG
GTGGGACAGTGTGCACAGTGTGGGGGCAGGGGAGGGCTAAGCAGGCCTGGGTTTGAGGGCTGCTCCGGAGACCGTCACTCCAGGTGCATT
CTGGAAGCATTAGACCCCAGGATGGAGCGACCAGCATGTCATCCATGTGGAATCTTGGTGGCTTTGAGGACATTCTGGAAAATGCCACTG
ACCAGTGTGAACAAAAGGGATGTGTTATGGGGCTGGAGGTGTGATTAGGTAGGAGGGAAACTGTTGGACCGACTCCTGCCCCCTGCTCAA
CACTGACCCCTCTGAGTGGTTGGAGGCAGTGCCCCAGTGCCCAGAAATCCCACCATTAGTGATTGTTTTTTATGAGAAAGAGGCGTGGAG
AAGTATTGGGGCAATGTGTCAGGGAGGAATCACCACATCCCTACGGCAGTCCCAGCCAAGCCCCCAATCCCAGCGGAGACTGTGCCCTGC
TCAGAGCTCCCAAGCCTTCCCCCACCACCTCACTCAAGTGCCCCTGAAATCCCTGCCAGACGGCTCAGCCTGGTCTGCGGTAAGGCAGGG
AGGCTGGAACCATTTCTGGGCATTGTGGTCATTCCCACTGTGTTCCTCCACCTCCTCCCTCCAGCGTTGCTCAGACCTCTGTCTTGGGAG
AAAGGTTGAGATAAGAATGTCCCATGGAGTGCCGTGGGCAACAGTGGCCCTTCATGGGAACAATCTGTTGGAGCAGGGGGTCAGTTCTCT
GCTGGGAATCTACCCCTTTCTGGAGGAGAAACCCATTCCACCTTAATAACTTTATTGTAATGTGAGAAACACAAAACAAAGTTTACTTTT
TTGACTCTAAGCTGACATGATATTAGAAAATCTCTCGCTCTCTTTTTTTTTTTTTTTTTTTTTTTTGGCTACTTGAGTTGTGGTCCTAAA
ACATAAAATCTGATGGACAAACAGAGGGTTGCTGGGGGGACAAGCGTGGGCACAATTTCCCCACCAAGACACCCTGATCTTCAGGCGGGT
CTCAGGAGCTTCTAAAAATCCGCATGGCTCTCCTGAGAGTGGACAGAGGAGAGGAGAGGGTCAGAAATGAACGCTCTTCTATTTCTTGTC
ATTACCAAGCCAATTACTTTTGCCAAATTTTTCTGTGATCTGCCCTGATTAAGATGAATTGTGAAATTTACATCAAGCAATTATCAAAGC
GGGCTGGGTCCCATCAGAACGACCCACATCTTTCTGTGGGTGTGAATGTCATTAGGTCTTGCGCTGACCCCTGAGCCCCCATCACTGCCG
CCTGATGGGGCAAAGAAACAAAAAACATTTCTTACTCTTCTGTGTTTTAACAAAAGTTTATAAAACAAAATAAATGGCGCATATGTTTTC

>83599_83599_7_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000316099_length(amino acids)=441AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_8_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000316673_length(transcript)=1599nt_BP=283nt
CAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCC
TGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGC
CCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATG
GGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGG
GACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTAC
TCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGC
ATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCG
CTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATC
GCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGAC
GACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTC
CTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTG
CCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGAT
CCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTT
GGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCC
AAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCCAGCGATGCACCCCATGCCCACCACCCCCTGCACCCTCACCTGATG
CAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCCACTCACCTCAGCAACGGACAGATGTGTGAGTGGCCCCGACCCAGG
GGACAGGCAGCCACCCCTGAGACCCCACAGCCCTCACCGCCAGGTGGCTCAGGGTCTGAGCCCTATAAGCTCCTGCCGGGAGCCGTCGCC

>83599_83599_8_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000316673_length(amino acids)=441AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_9_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000415691_length(transcript)=2398nt_BP=283nt
CAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCC
TGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGC
CCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATG
GGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGG
GACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTAC
TCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGC
ATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCG
CTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATC
GCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGAC
GACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTC
CTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTG
CCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGAT
CCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTT
GGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCC
AAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCCAGCGATGCACCCCATGCCCACCACCCCCTGCACCCTCACCTGATG
CAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCCACTCACCTCAGCAACGGACAGATGTCCACCCCTGAGACCCCACAG
CCCTCACCGCCAGGTGGCTCAGGGTCTGAGCCCTATAAGCTCCTGCCGGGAGCCGTCGCCACAATCGTCAAGCCCCTCTCTGCCATCCCC
CAGCCGACCATCACCAAGCAGGAAGTTATCTAGCAAGCCGCTGGGGCTTGGGGGCTCCACTGGCTCCCCCCAGCCCCCTAAGAGAGCACC
TGGTGATCACGTGGTCACGGCAAAGGAAGACGTGATGCCAGGACCAGTCCCAGAGCAGGAATGGGAAGGATGAAGGGCCCGAGAACATGG
CCTAAGGGCCACATCCCACTGCCACCCTTGACGCCCTGCTCTGGATAACAAGACTTTGACTTGGGGAGACCTCTACTGCCTTGGACAACT
TTTCTCATGTTGAAGCCACTGCCTTCACCTTCACCTTCATCCATGTCCAACCCCCGACTTCATCCCAAAGGACAGCCGCCTGGAGATGAC
TTGAGGCCTTACTTAAACCCAGCTCCCTTCTTCCCTAGCCTGGTGCTTCTCCTCTCCTAGCCCCTGTCATGGTGTCCAGACAGAGCCCTG
TGAGGCTGGGTCCAATTGTGGCACTTGGGGCACCTTGCTCCTCCTTCTGCTGCTGCCCCCACCTCTGCTGCCTCCCTCTGCTGTCACCTT
GCTCAGCCATCCCGTCTTCTCCAACACCACCTCTCCAGAGGCCAAGGAGGCCTTGGAAACGATTCCCCCAGTCATTCTGGGAACATGTTG
TAAGCACTGACTGGGACCAGGCACCAGGCAGGGTCTAGAAGGCTGTGGTGAGGGAAGACGCCTTTCTCCTCCAACCCAACCTCATCCTCC
TTCTTCAGGGACTTGGGTGGGTACTTGGGTGAGGATCCCTGAAGGCCTTCAACCCGAGAAAACAAACCCAGGTTGGCGACTGCAACAGGA

>83599_83599_9_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000415691_length(amino acids)=431AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_10_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000443598_length(transcript)=1682nt_BP=283nt
CAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCC
TGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGC
CCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATG
GGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGG
GACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTAC
TCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGC
ATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCG
CTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATC
GCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGAC
GACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTC
CTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTG
CCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGAT
CCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTT
GGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCC
AAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGTCCGTGCCAAGCCCAGGAGGGGCGGGGTTGGAGTGGGGACTCCCCAGGAGAC
AGGCCTCACACAGTGAGCTCACCCCTCAGCTCCTTGGCTTCCCCACTGTGCCGCTTTGGGCAAGTTGCTTAACCTGTCTGTGCCTCAGTT
TCCTCACCAGAAAAATGGGAACAAGGCAATGGTCTATTTGTTCAGGCACCGAGAACCTAGCACGTGCCAGTCACTGTTCTAAGTGCTGGC
AATTCAGCAAAGAACAAGATCTTTGCCCTCGGGGAGGCTGTGTGTGTGTGAGTATGTATGGATGCGTGGATATCTGTGTATATGCCCGTA

>83599_83599_10_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000443598_length(amino acids)=384AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGPCQAQEGRGWSGDSPG

--------------------------------------------------------------
>83599_83599_11_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000457232_length(transcript)=1569nt_BP=283nt
CAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCC
TGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGC
CCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATG
GGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGG
GACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTAC
TCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGC
ATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCG
CTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATC
GCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGAC
GACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTC
CTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTG
CCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGAT
CCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTT
GGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCC
AAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCCAGCGATGCACCCCATGCCCACCACCCCCTGCACCCTCACCTGATG
CAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCCACTCACCTCAGCAACGGACAGATGTCCACCCCTGAGACCCCACAG
CCCTCACCGCCAGGTGGCTCAGGGTCTGAGCCCTATAAGCTCCTGCCGGGAGCCGTCGCCACAATCGTCAAGCCCCTCTCTGCCATCCCC

>83599_83599_11_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000457232_length(amino acids)=431AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_12_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000609795_length(transcript)=1422nt_BP=283nt
CAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAGTTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCC
TGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGC
CCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCTGAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATG
GGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAACGCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGG
GACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGCTGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTAC
TCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGGAACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGC
ATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACTCGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCG
CTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTCTCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATC
GCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTTGAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGAC
GACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTGCTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTC
CTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCGGAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTG
CCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTCAAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGAT
CCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTGGAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTT
GGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGGCAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCC
AAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGTCCGTGCCAAGCCCAGGAGGGGCGGGGTTGGAGTGGGGACTCCCCAGGAGAC

>83599_83599_12_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000525650_HNF4A_chr20_43034698_ENST00000609795_length(amino acids)=384AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGPCQAQEGRGWSGDSPG

--------------------------------------------------------------
>83599_83599_13_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000316099_length(transcript)=4818nt_BP=328nt
CTTCTATACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAG
TTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCG
TTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCT
GAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAAC
GCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGC
TGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGG
AACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACT
CGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTC
TCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTT
GAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTG
CTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCG
GAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTC
AAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTG
GAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGG
CAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCC
AGCGATGCACCCCATGCCCACCACCCCCTGCACCCTCACCTGATGCAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCC
ACTCACCTCAGCAACGGACAGATGTGTGAGTGGCCCCGACCCAGGGGACAGGCAGCCACCCCTGAGACCCCACAGCCCTCACCGCCAGGT
GGCTCAGGGTCTGAGCCCTATAAGCTCCTGCCGGGAGCCGTCGCCACAATCGTCAAGCCCCTCTCTGCCATCCCCCAGCCGACCATCACC
AAGCAGGAAGTTATCTAGCAAGCCGCTGGGGCTTGGGGGCTCCACTGGCTCCCCCCAGCCCCCTAAGAGAGCACCTGGTGATCACGTGGT
CACGGCAAAGGAAGACGTGATGCCAGGACCAGTCCCAGAGCAGGAATGGGAAGGATGAAGGGCCCGAGAACATGGCCTAAGGGCCACATC
CCACTGCCACCCTTGACGCCCTGCTCTGGATAACAAGACTTTGACTTGGGGAGACCTCTACTGCCTTGGACAACTTTTCTCATGTTGAAG
CCACTGCCTTCACCTTCACCTTCATCCATGTCCAACCCCCGACTTCATCCCAAAGGACAGCCGCCTGGAGATGACTTGAGGCCTTACTTA
AACCCAGCTCCCTTCTTCCCTAGCCTGGTGCTTCTCCTCTCCTAGCCCCTGTCATGGTGTCCAGACAGAGCCCTGTGAGGCTGGGTCCAA
TTGTGGCACTTGGGGCACCTTGCTCCTCCTTCTGCTGCTGCCCCCACCTCTGCTGCCTCCCTCTGCTGTCACCTTGCTCAGCCATCCCGT
CTTCTCCAACACCACCTCTCCAGAGGCCAAGGAGGCCTTGGAAACGATTCCCCCAGTCATTCTGGGAACATGTTGTAAGCACTGACTGGG
ACCAGGCACCAGGCAGGGTCTAGAAGGCTGTGGTGAGGGAAGACGCCTTTCTCCTCCAACCCAACCTCATCCTCCTTCTTCAGGGACTTG
GGTGGGTACTTGGGTGAGGATCCCTGAAGGCCTTCAACCCGAGAAAACAAACCCAGGTTGGCGACTGCAACAGGAACTTGGAGTGGAGAG
GAAAAGCATCAGAAAGAGGCAGACCATCCACCAGGCCTTTGAGAAAGGGTAGAATTCTGGCTGGTAGAGCAGGTGAGATGGGACATTCCA
AAGAACAGCCTGAGCCAAGGCCTAGTGGTAGTAAGAATCTAGCAAGAATTGAGGAAGAATGGTGTGGGAGAGGGATGATGAAGAGAGAGA
GGGCCTGCTGGAGAGCATAGGGTCTGGAACACCAGGCTGAGGTCCTGATCAGCTTCAAGGAGTATGCAGGGAGCTGGGCTTCCAGAAAAT
GAACACAGCAGTTCTGCAGAGGACGGGAGGCTGGAAGCTGGGAGGTCAGGTGGGGTGGATGATATAATGCGGGTGAGAGTAATGAGGCTT
GGGGCTGGAGAGGACAAGATGGGTAAACCCTCACATCAGAGTGACATCCAGGAGGAATAAGCTCCCAGGGCCTGTCTCAAGCTCTTCCTT
ACTCCCAGGCACTGTCTTAAGGCATCTGACATGCATCATCTCATTTAATCCTCCCTTCCTCCCTATTAACCTAGAGATTGTTTTTGTTTT
TTATTCTCCTCCTCCCTCCCCGCCCTCACCCGCCCCACTCCCTCCTAACCTAGAGATTGTTACAGAAGCTGAAATTGCGTTCTAAGAGGT
GAAGTGATTTTTTTTCTGAAACTCACACAACTAGGAAGTGGCTGAGTCAGGACTTGAACCCAGGTCTCCCTGGATCAGAACAGGAGCTCT
TAACTACAGTGGCTGAATAGCTTCTCCAAAGGCTCCCTGTGTTCTCACCGTGATCAAGTTGAGGGGCTTCCGGCTCCCTTCTACAGCCTC
AGAAACCAGACTCGTTCTTCTGGGAACCCTGCCCACTCCCAGGACCAAGATTGGCCTGAGGCTGCACTAAAATTCACTTAGGGTCGAGCA
TCCTGTTTGCTGATAAATATTAAGGAGAATTCATGACTCTTGACAGCTTTTCTCTCTTCACTCCCCAAGTCAAGGGGAGGGGTGGCAGGG
GTCTGTTTCCTGGAAGTCAGGCTCATCTGGCCTGTTGGCATGGGGGTGGGACAGTGTGCACAGTGTGGGGGCAGGGGAGGGCTAAGCAGG
CCTGGGTTTGAGGGCTGCTCCGGAGACCGTCACTCCAGGTGCATTCTGGAAGCATTAGACCCCAGGATGGAGCGACCAGCATGTCATCCA
TGTGGAATCTTGGTGGCTTTGAGGACATTCTGGAAAATGCCACTGACCAGTGTGAACAAAAGGGATGTGTTATGGGGCTGGAGGTGTGAT
TAGGTAGGAGGGAAACTGTTGGACCGACTCCTGCCCCCTGCTCAACACTGACCCCTCTGAGTGGTTGGAGGCAGTGCCCCAGTGCCCAGA
AATCCCACCATTAGTGATTGTTTTTTATGAGAAAGAGGCGTGGAGAAGTATTGGGGCAATGTGTCAGGGAGGAATCACCACATCCCTACG
GCAGTCCCAGCCAAGCCCCCAATCCCAGCGGAGACTGTGCCCTGCTCAGAGCTCCCAAGCCTTCCCCCACCACCTCACTCAAGTGCCCCT
GAAATCCCTGCCAGACGGCTCAGCCTGGTCTGCGGTAAGGCAGGGAGGCTGGAACCATTTCTGGGCATTGTGGTCATTCCCACTGTGTTC
CTCCACCTCCTCCCTCCAGCGTTGCTCAGACCTCTGTCTTGGGAGAAAGGTTGAGATAAGAATGTCCCATGGAGTGCCGTGGGCAACAGT
GGCCCTTCATGGGAACAATCTGTTGGAGCAGGGGGTCAGTTCTCTGCTGGGAATCTACCCCTTTCTGGAGGAGAAACCCATTCCACCTTA
ATAACTTTATTGTAATGTGAGAAACACAAAACAAAGTTTACTTTTTTGACTCTAAGCTGACATGATATTAGAAAATCTCTCGCTCTCTTT
TTTTTTTTTTTTTTTTTTTTTGGCTACTTGAGTTGTGGTCCTAAAACATAAAATCTGATGGACAAACAGAGGGTTGCTGGGGGGACAAGC
GTGGGCACAATTTCCCCACCAAGACACCCTGATCTTCAGGCGGGTCTCAGGAGCTTCTAAAAATCCGCATGGCTCTCCTGAGAGTGGACA
GAGGAGAGGAGAGGGTCAGAAATGAACGCTCTTCTATTTCTTGTCATTACCAAGCCAATTACTTTTGCCAAATTTTTCTGTGATCTGCCC
TGATTAAGATGAATTGTGAAATTTACATCAAGCAATTATCAAAGCGGGCTGGGTCCCATCAGAACGACCCACATCTTTCTGTGGGTGTGA
ATGTCATTAGGTCTTGCGCTGACCCCTGAGCCCCCATCACTGCCGCCTGATGGGGCAAAGAAACAAAAAACATTTCTTACTCTTCTGTGT

>83599_83599_13_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000316099_length(amino acids)=441AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_14_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000316673_length(transcript)=1644nt_BP=328nt
CTTCTATACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAG
TTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCG
TTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCT
GAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAAC
GCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGC
TGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGG
AACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACT
CGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTC
TCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTT
GAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTG
CTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCG
GAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTC
AAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTG
GAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGG
CAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCC
AGCGATGCACCCCATGCCCACCACCCCCTGCACCCTCACCTGATGCAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCC
ACTCACCTCAGCAACGGACAGATGTGTGAGTGGCCCCGACCCAGGGGACAGGCAGCCACCCCTGAGACCCCACAGCCCTCACCGCCAGGT
GGCTCAGGGTCTGAGCCCTATAAGCTCCTGCCGGGAGCCGTCGCCACAATCGTCAAGCCCCTCTCTGCCATCCCCCAGCCGACCATCACC

>83599_83599_14_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000316673_length(amino acids)=441AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_15_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000415691_length(transcript)=2443nt_BP=328nt
CTTCTATACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAG
TTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCG
TTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCT
GAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAAC
GCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGC
TGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGG
AACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACT
CGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTC
TCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTT
GAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTG
CTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCG
GAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTC
AAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTG
GAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGG
CAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCC
AGCGATGCACCCCATGCCCACCACCCCCTGCACCCTCACCTGATGCAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCC
ACTCACCTCAGCAACGGACAGATGTCCACCCCTGAGACCCCACAGCCCTCACCGCCAGGTGGCTCAGGGTCTGAGCCCTATAAGCTCCTG
CCGGGAGCCGTCGCCACAATCGTCAAGCCCCTCTCTGCCATCCCCCAGCCGACCATCACCAAGCAGGAAGTTATCTAGCAAGCCGCTGGG
GCTTGGGGGCTCCACTGGCTCCCCCCAGCCCCCTAAGAGAGCACCTGGTGATCACGTGGTCACGGCAAAGGAAGACGTGATGCCAGGACC
AGTCCCAGAGCAGGAATGGGAAGGATGAAGGGCCCGAGAACATGGCCTAAGGGCCACATCCCACTGCCACCCTTGACGCCCTGCTCTGGA
TAACAAGACTTTGACTTGGGGAGACCTCTACTGCCTTGGACAACTTTTCTCATGTTGAAGCCACTGCCTTCACCTTCACCTTCATCCATG
TCCAACCCCCGACTTCATCCCAAAGGACAGCCGCCTGGAGATGACTTGAGGCCTTACTTAAACCCAGCTCCCTTCTTCCCTAGCCTGGTG
CTTCTCCTCTCCTAGCCCCTGTCATGGTGTCCAGACAGAGCCCTGTGAGGCTGGGTCCAATTGTGGCACTTGGGGCACCTTGCTCCTCCT
TCTGCTGCTGCCCCCACCTCTGCTGCCTCCCTCTGCTGTCACCTTGCTCAGCCATCCCGTCTTCTCCAACACCACCTCTCCAGAGGCCAA
GGAGGCCTTGGAAACGATTCCCCCAGTCATTCTGGGAACATGTTGTAAGCACTGACTGGGACCAGGCACCAGGCAGGGTCTAGAAGGCTG
TGGTGAGGGAAGACGCCTTTCTCCTCCAACCCAACCTCATCCTCCTTCTTCAGGGACTTGGGTGGGTACTTGGGTGAGGATCCCTGAAGG
CCTTCAACCCGAGAAAACAAACCCAGGTTGGCGACTGCAACAGGAACTTGGAGTGGAGAGGAAAAGCATCAGAAAGAGGCAGACCATCCA

>83599_83599_15_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000415691_length(amino acids)=431AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_16_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000443598_length(transcript)=1727nt_BP=328nt
CTTCTATACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAG
TTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCG
TTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCT
GAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAAC
GCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGC
TGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGG
AACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACT
CGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTC
TCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTT
GAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTG
CTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCG
GAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTC
AAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTG
GAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGG
CAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGTCCGTGC
CAAGCCCAGGAGGGGCGGGGTTGGAGTGGGGACTCCCCAGGAGACAGGCCTCACACAGTGAGCTCACCCCTCAGCTCCTTGGCTTCCCCA
CTGTGCCGCTTTGGGCAAGTTGCTTAACCTGTCTGTGCCTCAGTTTCCTCACCAGAAAAATGGGAACAAGGCAATGGTCTATTTGTTCAG
GCACCGAGAACCTAGCACGTGCCAGTCACTGTTCTAAGTGCTGGCAATTCAGCAAAGAACAAGATCTTTGCCCTCGGGGAGGCTGTGTGT
GTGTGAGTATGTATGGATGCGTGGATATCTGTGTATATGCCCGTATGTGCGTGCATGTGTATATAAAGCCTCACATTTTATGATTTTGAA

>83599_83599_16_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000443598_length(amino acids)=384AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGPCQAQEGRGWSGDSPG

--------------------------------------------------------------
>83599_83599_17_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000457232_length(transcript)=1614nt_BP=328nt
CTTCTATACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAG
TTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCG
TTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCT
GAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAAC
GCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGC
TGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGG
AACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACT
CGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTC
TCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTT
GAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTG
CTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCG
GAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTC
AAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTG
GAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGG
CAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGGTCCCCC
AGCGATGCACCCCATGCCCACCACCCCCTGCACCCTCACCTGATGCAGGAACATATGGGAACCAACGTCATCGTTGCCAACACAATGCCC
ACTCACCTCAGCAACGGACAGATGTCCACCCCTGAGACCCCACAGCCCTCACCGCCAGGTGGCTCAGGGTCTGAGCCCTATAAGCTCCTG

>83599_83599_17_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000457232_length(amino acids)=431AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHL

--------------------------------------------------------------
>83599_83599_18_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000609795_length(transcript)=1467nt_BP=328nt
CTTCTATACAACCGTGGAGCCAGGGCAAGGGAGAGACAGAAGGAGCAAGTGACCCAGGGAGACAAACACTTGGAGATACTTGGGGCTGAG
TTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAGTCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCG
TTATTGCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCTTCCTCTCCCCTGCTAAGCTCCAGGTCCT
GAGATTAAATTAGGGGCTGGAGCTCACTGCACTCCAGCAGTCATGGGACCCAGGATAGACACGTCCCCATCAGAAGGCACCAACCTCAAC
GCGCCCAACAGCCTGGGTGTCAGCGCCCTGTGTGCCATCTGCGGGGACCGGGCCACGGGCAAACACTACGGTGCCTCGAGCTGTGACGGC
TGCAAGGGCTTCTTCCGGAGGAGCGTGCGGAAGAACCACATGTACTCCTGCAGATTTAGCCGGCAGTGCGTGGTGGACAAAGACAAGAGG
AACCAGTGCCGCTACTGCAGGCTCAAGAAATGCTTCCGGGCTGGCATGAAGAAGGAAGCCGTCCAGAATGAGCGGGACCGGATCAGCACT
CGAAGGTCAAGCTATGAGGACAGCAGCCTGCCCTCCATCAATGCGCTCCTGCAGGCGGAGGTCCTGTCCCGACAGATCACCTCCCCCGTC
TCCGGGATCAACGGCGACATTCGGGCGAAGAAGATTGCCAGCATCGCAGATGTGTGTGAGTCCATGAAGGAGCAGCTGCTGGTTCTCGTT
GAGTGGGCCAAGTACATCCCAGCTTTCTGCGAGCTCCCCCTGGACGACCAGGTGGCCCTGCTCAGAGCCCATGCTGGCGAGCACCTGCTG
CTCGGAGCCACCAAGAGATCCATGGTGTTCAAGGACGTGCTGCTCCTAGGCAATGACTACATTGTCCCTCGGCACTGCCCGGAGCTGGCG
GAGATGAGCCGGGTGTCCATACGCATCCTTGACGAGCTGGTGCTGCCCTTCCAGGAGCTGCAGATCGATGACAATGAGTATGCCTACCTC
AAAGCCATCATCTTCTTTGACCCAGATGCCAAGGGGCTGAGCGATCCAGGGAAGATCAAGCGGCTGCGTTCCCAGGTGCAGGTGAGCTTG
GAGGACTACATCAACGACCGCCAGTATGACTCGCGTGGCCGCTTTGGAGAGCTGCTGCTGCTGCTGCCCACCTTGCAGAGCATCACCTGG
CAGATGATCGAGCAGATCCAGTTCATCAAGCTCTTCGGCATGGCCAAGATTGACAACCTGTTGCAGGAGATGCTGCTGGGAGGTCCGTGC
CAAGCCCAGGAGGGGCGGGGTTGGAGTGGGGACTCCCCAGGAGACAGGCCTCACACAGTGAGCTCACCCCTCAGCTCCTTGGCTTCCCCA

>83599_83599_18_SLCO2B1-HNF4A_SLCO2B1_chr11_74862442_ENST00000531756_HNF4A_chr20_43034698_ENST00000609795_length(amino acids)=384AA_BP=5
MGPRIDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRA
GMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPL
DDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLS
DPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGPCQAQEGRGWSGDSPG

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SLCO2B1-HNF4A

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for SLCO2B1-HNF4A

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for SLCO2B1-HNF4A

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source