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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ATXN10-ARHGAP8 (FusionGDB2 ID:8365)

Fusion Gene Summary for ATXN10-ARHGAP8

check button Fusion gene summary
Fusion gene informationFusion gene name: ATXN10-ARHGAP8
Fusion gene ID: 8365
HgeneTgene
Gene symbol

ATXN10

ARHGAP8

Gene ID

25814

23779

Gene nameataxin 10Rho GTPase activating protein 8
SynonymsE46L|HUMEEP|SCA10BPGAP1|PP610
Cytomap

22q13.31

22q13.31

Type of geneprotein-codingprotein-coding
Descriptionataxin-10brain protein E46 homologspinocerebellar ataxia type 10 proteinrho GTPase-activating protein 8BCH domain-containing Cdc42GAP-like proteinBNIP-2 and Cdc42GAP homology domain-containing, proline-rich and Cdc42GAP-like protein subtype-1rho-type GTPase-activating protein 8
Modification date2020031320200313
UniProtAcc

Q9UBB4

P85298

Ensembl transtripts involved in fusion geneENST00000498009, ENST00000252934, 
ENST00000381061, ENST00000402380, 
ENST00000336963, ENST00000356099, 
ENST00000389773, ENST00000389774, 
ENST00000517296, ENST00000469872, 
Fusion gene scores* DoF score16 X 12 X 11=21126 X 9 X 5=270
# samples 197
** MAII scorelog2(19/2112*10)=-3.47453851102751
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/270*10)=-1.94753258010586
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATXN10 [Title/Abstract] AND ARHGAP8 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATXN10(46098727)-ARHGAP8(45221363), # samples:1
ATXN10(46098727)-ARHGAP8(45241149), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneATXN10

GO:0031175

neuron projection development

16498633

TgeneARHGAP8

GO:0070374

positive regulation of ERK1 and ERK2 cascade

20179103


check buttonFusion gene breakpoints across ATXN10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARHGAP8 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CG-4449-01AATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
ChimerDB4STADTCGA-CG-4449-01AATXN10chr22

46098727

+ARHGAP8chr22

45241149

+


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Fusion Gene ORF analysis for ATXN10-ARHGAP8

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000498009ENST00000336963ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
3UTR-3CDSENST00000498009ENST00000336963ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
3UTR-3CDSENST00000498009ENST00000356099ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
3UTR-3CDSENST00000498009ENST00000356099ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
3UTR-3CDSENST00000498009ENST00000389773ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
3UTR-3CDSENST00000498009ENST00000389773ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
3UTR-3CDSENST00000498009ENST00000389774ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
3UTR-3CDSENST00000498009ENST00000389774ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
3UTR-3CDSENST00000498009ENST00000517296ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
3UTR-3CDSENST00000498009ENST00000517296ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
3UTR-intronENST00000498009ENST00000469872ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
3UTR-intronENST00000498009ENST00000469872ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
5CDS-intronENST00000252934ENST00000469872ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
5CDS-intronENST00000252934ENST00000469872ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
5CDS-intronENST00000381061ENST00000469872ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
5CDS-intronENST00000381061ENST00000469872ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
In-frameENST00000252934ENST00000336963ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
In-frameENST00000252934ENST00000336963ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
In-frameENST00000252934ENST00000356099ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
In-frameENST00000252934ENST00000356099ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
In-frameENST00000252934ENST00000389773ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
In-frameENST00000252934ENST00000389773ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
In-frameENST00000252934ENST00000389774ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
In-frameENST00000252934ENST00000389774ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
In-frameENST00000252934ENST00000517296ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
In-frameENST00000252934ENST00000517296ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
In-frameENST00000381061ENST00000336963ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
In-frameENST00000381061ENST00000336963ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
In-frameENST00000381061ENST00000356099ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
In-frameENST00000381061ENST00000356099ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
In-frameENST00000381061ENST00000389773ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
In-frameENST00000381061ENST00000389773ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
In-frameENST00000381061ENST00000389774ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
In-frameENST00000381061ENST00000389774ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
In-frameENST00000381061ENST00000517296ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
In-frameENST00000381061ENST00000517296ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
intron-3CDSENST00000402380ENST00000336963ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
intron-3CDSENST00000402380ENST00000336963ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
intron-3CDSENST00000402380ENST00000356099ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
intron-3CDSENST00000402380ENST00000356099ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
intron-3CDSENST00000402380ENST00000389773ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
intron-3CDSENST00000402380ENST00000389773ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
intron-3CDSENST00000402380ENST00000389774ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
intron-3CDSENST00000402380ENST00000389774ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
intron-3CDSENST00000402380ENST00000517296ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
intron-3CDSENST00000402380ENST00000517296ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+
intron-intronENST00000402380ENST00000469872ATXN10chr22

46098727

+ARHGAP8chr22

45221363

+
intron-intronENST00000402380ENST00000469872ATXN10chr22

46098727

+ARHGAP8chr22

45241149

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000381061ATXN10chr2246098727+ENST00000517296ARHGAP8chr2245221363+16497212661537423
ENST00000381061ATXN10chr2246098727+ENST00000389773ARHGAP8chr2245221363+17277212661537423
ENST00000381061ATXN10chr2246098727+ENST00000389774ARHGAP8chr2245221363+17277212661537423
ENST00000381061ATXN10chr2246098727+ENST00000336963ARHGAP8chr2245221363+16247212661153295
ENST00000381061ATXN10chr2246098727+ENST00000356099ARHGAP8chr2245221363+17277212661537423
ENST00000252934ATXN10chr2246098727+ENST00000517296ARHGAP8chr2245221363+18409122651728487
ENST00000252934ATXN10chr2246098727+ENST00000389773ARHGAP8chr2245221363+19189122651728487
ENST00000252934ATXN10chr2246098727+ENST00000389774ARHGAP8chr2245221363+19189122651728487
ENST00000252934ATXN10chr2246098727+ENST00000336963ARHGAP8chr2245221363+18159122651344359
ENST00000252934ATXN10chr2246098727+ENST00000356099ARHGAP8chr2245221363+19189122651728487
ENST00000381061ATXN10chr2246098727+ENST00000517296ARHGAP8chr2245241149+15387212661426386
ENST00000381061ATXN10chr2246098727+ENST00000389773ARHGAP8chr2245241149+16167212661426386
ENST00000381061ATXN10chr2246098727+ENST00000389774ARHGAP8chr2245241149+16167212661426386
ENST00000381061ATXN10chr2246098727+ENST00000336963ARHGAP8chr2245241149+15137212661042258
ENST00000381061ATXN10chr2246098727+ENST00000356099ARHGAP8chr2245241149+16167212661426386
ENST00000252934ATXN10chr2246098727+ENST00000517296ARHGAP8chr2245241149+17299122651617450
ENST00000252934ATXN10chr2246098727+ENST00000389773ARHGAP8chr2245241149+18079122651617450
ENST00000252934ATXN10chr2246098727+ENST00000389774ARHGAP8chr2245241149+18079122651617450
ENST00000252934ATXN10chr2246098727+ENST00000336963ARHGAP8chr2245241149+17049122651233322
ENST00000252934ATXN10chr2246098727+ENST00000356099ARHGAP8chr2245241149+18079122651617450

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000381061ENST00000517296ATXN10chr2246098727+ARHGAP8chr2245221363+0.0120148040.9879852
ENST00000381061ENST00000389773ATXN10chr2246098727+ARHGAP8chr2245221363+0.0112508710.98874915
ENST00000381061ENST00000389774ATXN10chr2246098727+ARHGAP8chr2245221363+0.0112508710.98874915
ENST00000381061ENST00000336963ATXN10chr2246098727+ARHGAP8chr2245221363+0.0049061340.9950938
ENST00000381061ENST00000356099ATXN10chr2246098727+ARHGAP8chr2245221363+0.0112508710.98874915
ENST00000252934ENST00000517296ATXN10chr2246098727+ARHGAP8chr2245221363+0.0193395320.9806605
ENST00000252934ENST00000389773ATXN10chr2246098727+ARHGAP8chr2245221363+0.0177816970.9822183
ENST00000252934ENST00000389774ATXN10chr2246098727+ARHGAP8chr2245221363+0.0177816970.9822183
ENST00000252934ENST00000336963ATXN10chr2246098727+ARHGAP8chr2245221363+0.0079828960.99201715
ENST00000252934ENST00000356099ATXN10chr2246098727+ARHGAP8chr2245221363+0.0177816970.9822183
ENST00000381061ENST00000517296ATXN10chr2246098727+ARHGAP8chr2245241149+0.007140240.9928598
ENST00000381061ENST00000389773ATXN10chr2246098727+ARHGAP8chr2245241149+0.0068069670.9931931
ENST00000381061ENST00000389774ATXN10chr2246098727+ARHGAP8chr2245241149+0.0068069670.9931931
ENST00000381061ENST00000336963ATXN10chr2246098727+ARHGAP8chr2245241149+0.0036098970.99639004
ENST00000381061ENST00000356099ATXN10chr2246098727+ARHGAP8chr2245241149+0.0068069670.9931931
ENST00000252934ENST00000517296ATXN10chr2246098727+ARHGAP8chr2245241149+0.0137130810.98628694
ENST00000252934ENST00000389773ATXN10chr2246098727+ARHGAP8chr2245241149+0.0126996160.98730046
ENST00000252934ENST00000389774ATXN10chr2246098727+ARHGAP8chr2245241149+0.0126996160.98730046
ENST00000252934ENST00000336963ATXN10chr2246098727+ARHGAP8chr2245241149+0.0049360720.99506396
ENST00000252934ENST00000356099ATXN10chr2246098727+ARHGAP8chr2245241149+0.0126996160.98730046

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Fusion Genomic Features for ATXN10-ARHGAP8


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ATXN10chr2246098727+ARHGAP8chr2245221362+0.233588070.76641196
ATXN10chr2246098727+ARHGAP8chr2245241148+7.16E-060.99999285
ATXN10chr2246098727+ARHGAP8chr2245221362+0.233588070.76641196
ATXN10chr2246098727+ARHGAP8chr2245241148+7.16E-060.99999285

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ATXN10-ARHGAP8


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:46098727/chr22:45221363)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATXN10

Q9UBB4

ARHGAP8

P85298

FUNCTION: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. {ECO:0000250}.FUNCTION: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARHGAP8chr22:46098727chr22:45221363ENST00000356099512226_412161434.0DomainRho-GAP
TgeneARHGAP8chr22:46098727chr22:45221363ENST00000389774613226_412192465.0DomainRho-GAP
TgeneARHGAP8chr22:46098727chr22:45241149ENST00000356099612226_412198434.0DomainRho-GAP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARHGAP8chr22:46098727chr22:45221363ENST0000035609951213_199161434.0DomainCRAL-TRIO
TgeneARHGAP8chr22:46098727chr22:45221363ENST0000038977461313_199192465.0DomainCRAL-TRIO
TgeneARHGAP8chr22:46098727chr22:45241149ENST0000035609961213_199198434.0DomainCRAL-TRIO
TgeneARHGAP8chr22:46098727chr22:45241149ENST0000038977471313_199229465.0DomainCRAL-TRIO
TgeneARHGAP8chr22:46098727chr22:45241149ENST00000389774713226_412229465.0DomainRho-GAP


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Fusion Gene Sequence for ATXN10-ARHGAP8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8365_8365_1_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45221363_ENST00000336963_length(transcript)=1815nt_BP=912nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTAT
TGTTTGGGTGCATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTT
TACATCCCTTAATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGA
ATCAGAATGGCCGTACGATGAGAAGCTCCAGAGCCTGCACGAGGGCCGGACGCCGCCTCCCACCAAGACACCACCGCCGCGGCCCCCGCT
GCCCACACAGCAGTTTGGCGTCAGTCTGCAATACCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGAC
GTACCTGAGAGAGAAAGGCCTGCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAA
CCAAGGGAAGCCCGTGAACTTTGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCC
GCTTCTGACCTTCCAGGCCTACGAGCAGATTCTCGGGATCACCTGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGG
CCTGTGTCTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGC
TGATCGAGTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCC
CTTTGCAGGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTC
TCTAGTGTTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAA
TAACCAGCCATTAGATGAATTCAGAACCTTCTAATGAAAACTCCATGCCTCTGGTCCTTGGACTCTTGTCCATGGTTCCTGAGCTGTGGA

>8365_8365_1_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45221363_ENST00000336963_length(amino acids)=359AA_BP=216
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVWVHAFPELFLSCLNHPDKKIVAYSSMI
LFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFT

--------------------------------------------------------------
>8365_8365_2_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45221363_ENST00000356099_length(transcript)=1918nt_BP=912nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTAT
TGTTTGGGTGCATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTT
TACATCCCTTAATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGA
ATCAGAATGGCCGTACGATGAGAAGCTCCAGAGCCTGCACGAGGGCCGGACGCCGCCTCCCACCAAGACACCACCGCCGCGGCCCCCGCT
GCCCACACAGCAGTTTGGCGTCAGTCTGCAATACCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGAC
GTACCTGAGAGAGAAAGGCCTGCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAA
CCAAGGGAAGCCCGTGAACTTTGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCC
GCTTCTGACCTTCCAGGCCTACGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACG
GAGCCTCCCAGAGCACAACTACGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAA
CAGCTCTAACCTGGCCTGTGTCTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACAT
GTTCACTGAACTGCTGATCGAGTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGG
GAGCAGGGCAGCCCCTTTGCAGGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGC
AGCCAGAAGACGTCTCTAGTGTTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTT
GGCATCTGTAAAAATAACCAGCCATTAGATGAATTCAGAACCTTCTAATGAAAACTCCATGCCTCTGGTCCTTGGACTCTTGTCCATGGT

>8365_8365_2_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45221363_ENST00000356099_length(amino acids)=487AA_BP=216
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVWVHAFPELFLSCLNHPDKKIVAYSSMI
LFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFT
VTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI
LRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWE

--------------------------------------------------------------
>8365_8365_3_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45221363_ENST00000389773_length(transcript)=1918nt_BP=912nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTAT
TGTTTGGGTGCATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTT
TACATCCCTTAATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGA
ATCAGAATGGCCGTACGATGAGAAGCTCCAGAGCCTGCACGAGGGCCGGACGCCGCCTCCCACCAAGACACCACCGCCGCGGCCCCCGCT
GCCCACACAGCAGTTTGGCGTCAGTCTGCAATACCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGAC
GTACCTGAGAGAGAAAGGCCTGCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAA
CCAAGGGAAGCCCGTGAACTTTGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCC
GCTTCTGACCTTCCAGGCCTACGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACG
GAGCCTCCCAGAGCACAACTACGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAA
CAGCTCTAACCTGGCCTGTGTCTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACAT
GTTCACTGAACTGCTGATCGAGTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGG
GAGCAGGGCAGCCCCTTTGCAGGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGC
AGCCAGAAGACGTCTCTAGTGTTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTT
GGCATCTGTAAAAATAACCAGCCATTAGATGAATTCAGAACCTTCTAATGAAAACTCCATGCCTCTGGTCCTTGGACTCTTGTCCATGGT

>8365_8365_3_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45221363_ENST00000389773_length(amino acids)=487AA_BP=216
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVWVHAFPELFLSCLNHPDKKIVAYSSMI
LFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFT
VTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI
LRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWE

--------------------------------------------------------------
>8365_8365_4_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45221363_ENST00000389774_length(transcript)=1918nt_BP=912nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTAT
TGTTTGGGTGCATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTT
TACATCCCTTAATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGA
ATCAGAATGGCCGTACGATGAGAAGCTCCAGAGCCTGCACGAGGGCCGGACGCCGCCTCCCACCAAGACACCACCGCCGCGGCCCCCGCT
GCCCACACAGCAGTTTGGCGTCAGTCTGCAATACCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGAC
GTACCTGAGAGAGAAAGGCCTGCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAA
CCAAGGGAAGCCCGTGAACTTTGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCC
GCTTCTGACCTTCCAGGCCTACGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACG
GAGCCTCCCAGAGCACAACTACGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAA
CAGCTCTAACCTGGCCTGTGTCTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACAT
GTTCACTGAACTGCTGATCGAGTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGG
GAGCAGGGCAGCCCCTTTGCAGGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGC
AGCCAGAAGACGTCTCTAGTGTTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTT
GGCATCTGTAAAAATAACCAGCCATTAGATGAATTCAGAACCTTCTAATGAAAACTCCATGCCTCTGGTCCTTGGACTCTTGTCCATGGT

>8365_8365_4_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45221363_ENST00000389774_length(amino acids)=487AA_BP=216
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVWVHAFPELFLSCLNHPDKKIVAYSSMI
LFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFT
VTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI
LRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWE

--------------------------------------------------------------
>8365_8365_5_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45221363_ENST00000517296_length(transcript)=1840nt_BP=912nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTAT
TGTTTGGGTGCATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTT
TACATCCCTTAATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGA
ATCAGAATGGCCGTACGATGAGAAGCTCCAGAGCCTGCACGAGGGCCGGACGCCGCCTCCCACCAAGACACCACCGCCGCGGCCCCCGCT
GCCCACACAGCAGTTTGGCGTCAGTCTGCAATACCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGAC
GTACCTGAGAGAGAAAGGCCTGCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAA
CCAAGGGAAGCCCGTGAACTTTGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCC
GCTTCTGACCTTCCAGGCCTACGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACG
GAGCCTCCCAGAGCACAACTACGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAA
CAGCTCTAACCTGGCCTGTGTCTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACAT
GTTCACTGAACTGCTGATCGAGTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGG
GAGCAGGGCAGCCCCTTTGCAGGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGC
AGCCAGAAGACGTCTCTAGTGTTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTT

>8365_8365_5_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45221363_ENST00000517296_length(amino acids)=487AA_BP=216
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVWVHAFPELFLSCLNHPDKKIVAYSSMI
LFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFT
VTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI
LRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWE

--------------------------------------------------------------
>8365_8365_6_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45241149_ENST00000336963_length(transcript)=1704nt_BP=912nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTAT
TGTTTGGGTGCATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTT
TACATCCCTTAATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGA
ATCAGAATGGCCCCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAGAGAAAGGCCT
GCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGCCCGTGAACTT
TGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCTTCCAGGCCTA
CGAGCAGATTCTCGGGATCACCTGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGGCCTGTGTCTTCGGGCTGAATT
TGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGCTGATCGAGTACTATGAAAAGA
TCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCCCTTTGCAGGAGGCTGTGCCAC
GGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTCTCTAGTGTTGCGAACACTCTG
TATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAATAACCAGCCATTAGATGAATT

>8365_8365_6_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45241149_ENST00000336963_length(amino acids)=322AA_BP=216
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVWVHAFPELFLSCLNHPDKKIVAYSSMI
LFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPV

--------------------------------------------------------------
>8365_8365_7_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45241149_ENST00000356099_length(transcript)=1807nt_BP=912nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTAT
TGTTTGGGTGCATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTT
TACATCCCTTAATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGA
ATCAGAATGGCCCCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAGAGAAAGGCCT
GCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGCCCGTGAACTT
TGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCTTCCAGGCCTA
CGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAGAGCACAACTA
CGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGGCCTGTGT
CTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGCTGATCGA
GTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCCCTTTGCA
GGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTCTCTAGTG
TTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAATAACCAG
CCATTAGATGAATTCAGAACCTTCTAATGAAAACTCCATGCCTCTGGTCCTTGGACTCTTGTCCATGGTTCCTGAGCTGTGGACCGGGAT

>8365_8365_7_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45241149_ENST00000356099_length(amino acids)=450AA_BP=216
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVWVHAFPELFLSCLNHPDKKIVAYSSMI
LFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPV
NFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLA
CVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL

--------------------------------------------------------------
>8365_8365_8_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45241149_ENST00000389773_length(transcript)=1807nt_BP=912nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTAT
TGTTTGGGTGCATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTT
TACATCCCTTAATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGA
ATCAGAATGGCCCCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAGAGAAAGGCCT
GCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGCCCGTGAACTT
TGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCTTCCAGGCCTA
CGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAGAGCACAACTA
CGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGGCCTGTGT
CTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGCTGATCGA
GTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCCCTTTGCA
GGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTCTCTAGTG
TTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAATAACCAG
CCATTAGATGAATTCAGAACCTTCTAATGAAAACTCCATGCCTCTGGTCCTTGGACTCTTGTCCATGGTTCCTGAGCTGTGGACCGGGAT

>8365_8365_8_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45241149_ENST00000389773_length(amino acids)=450AA_BP=216
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVWVHAFPELFLSCLNHPDKKIVAYSSMI
LFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPV
NFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLA
CVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL

--------------------------------------------------------------
>8365_8365_9_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45241149_ENST00000389774_length(transcript)=1807nt_BP=912nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTAT
TGTTTGGGTGCATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTT
TACATCCCTTAATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGA
ATCAGAATGGCCCCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAGAGAAAGGCCT
GCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGCCCGTGAACTT
TGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCTTCCAGGCCTA
CGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAGAGCACAACTA
CGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGGCCTGTGT
CTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGCTGATCGA
GTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCCCTTTGCA
GGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTCTCTAGTG
TTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAATAACCAG
CCATTAGATGAATTCAGAACCTTCTAATGAAAACTCCATGCCTCTGGTCCTTGGACTCTTGTCCATGGTTCCTGAGCTGTGGACCGGGAT

>8365_8365_9_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45241149_ENST00000389774_length(amino acids)=450AA_BP=216
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVWVHAFPELFLSCLNHPDKKIVAYSSMI
LFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPV
NFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLA
CVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL

--------------------------------------------------------------
>8365_8365_10_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45241149_ENST00000517296_length(transcript)=1729nt_BP=912nt
GGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGGC
GGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATCC
TACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGGC
GGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGCT
CTTCAAAGAGCAGCGGAACCGAGAAACAGCACCCAGGACTATCTTCCAAAGAGTTCTGGATATCCTAAAGAAATCTTCTCATGCTGTTGA
GCTTGCCTGCAGAGATCCATCCCAAGTGGAAAACCTGGCTTCCAGTCTGCAGTTAATAACAGAATGCTTCAGGTGTCTTCGCAATGCTTG
CATAGAGTGTTCTGTGAACCAGAATTCAATCAGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCG
AGTGGAACAGGAATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTAT
TGTTTGGGTGCATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTT
TACATCCCTTAATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGA
ATCAGAATGGCCCCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAGAGAAAGGCCT
GCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGCCCGTGAACTT
TGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCTTCCAGGCCTA
CGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAGAGCACAACTA
CGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGGCCTGTGT
CTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGCTGATCGA
GTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCCCTTTGCA
GGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTCTCTAGTG
TTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAATAACCAG

>8365_8365_10_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000252934_ARHGAP8_chr22_45241149_ENST00000517296_length(amino acids)=450AA_BP=216
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN
ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVWVHAFPELFLSCLNHPDKKIVAYSSMI
LFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPV
NFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLA
CVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL

--------------------------------------------------------------
>8365_8365_11_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45221363_ENST00000336963_length(transcript)=1624nt_BP=721nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTATTGTTTGGGTGC
ATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTTTACATCCCTTA
ATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGAATCAGAATGGC
CGTACGATGAGAAGCTCCAGAGCCTGCACGAGGGCCGGACGCCGCCTCCCACCAAGACACCACCGCCGCGGCCCCCGCTGCCCACACAGC
AGTTTGGCGTCAGTCTGCAATACCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAG
AGAAAGGCCTGCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGC
CCGTGAACTTTGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCT
TCCAGGCCTACGAGCAGATTCTCGGGATCACCTGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGGCCTGTGTCTTC
GGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGCTGATCGAGTAC
TATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCCCTTTGCAGGAG
GCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTCTCTAGTGTTGC
GAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAATAACCAGCCAT
TAGATGAATTCAGAACCTTCTAATGAAAACTCCATGCCTCTGGTCCTTGGACTCTTGTCCATGGTTCCTGAGCTGTGGACCGGGATAGAA

>8365_8365_11_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45221363_ENST00000336963_length(amino acids)=295AA_BP=152
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVW
VHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPYDEKLQSLHEGRTPPPTKTPPPRPPLPT
QQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLL

--------------------------------------------------------------
>8365_8365_12_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45221363_ENST00000356099_length(transcript)=1727nt_BP=721nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTATTGTTTGGGTGC
ATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTTTACATCCCTTA
ATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGAATCAGAATGGC
CGTACGATGAGAAGCTCCAGAGCCTGCACGAGGGCCGGACGCCGCCTCCCACCAAGACACCACCGCCGCGGCCCCCGCTGCCCACACAGC
AGTTTGGCGTCAGTCTGCAATACCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAG
AGAAAGGCCTGCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGC
CCGTGAACTTTGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCT
TCCAGGCCTACGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAG
AGCACAACTACGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACC
TGGCCTGTGTCTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAAC
TGCTGATCGAGTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAG
CCCCTTTGCAGGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGAC
GTCTCTAGTGTTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAA
AAATAACCAGCCATTAGATGAATTCAGAACCTTCTAATGAAAACTCCATGCCTCTGGTCCTTGGACTCTTGTCCATGGTTCCTGAGCTGT

>8365_8365_12_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45221363_ENST00000356099_length(amino acids)=423AA_BP=152
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVW
VHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPYDEKLQSLHEGRTPPPTKTPPPRPPLPT
QQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLL
TFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFT

--------------------------------------------------------------
>8365_8365_13_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45221363_ENST00000389773_length(transcript)=1727nt_BP=721nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTATTGTTTGGGTGC
ATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTTTACATCCCTTA
ATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGAATCAGAATGGC
CGTACGATGAGAAGCTCCAGAGCCTGCACGAGGGCCGGACGCCGCCTCCCACCAAGACACCACCGCCGCGGCCCCCGCTGCCCACACAGC
AGTTTGGCGTCAGTCTGCAATACCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAG
AGAAAGGCCTGCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGC
CCGTGAACTTTGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCT
TCCAGGCCTACGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAG
AGCACAACTACGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACC
TGGCCTGTGTCTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAAC
TGCTGATCGAGTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAG
CCCCTTTGCAGGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGAC
GTCTCTAGTGTTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAA
AAATAACCAGCCATTAGATGAATTCAGAACCTTCTAATGAAAACTCCATGCCTCTGGTCCTTGGACTCTTGTCCATGGTTCCTGAGCTGT

>8365_8365_13_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45221363_ENST00000389773_length(amino acids)=423AA_BP=152
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVW
VHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPYDEKLQSLHEGRTPPPTKTPPPRPPLPT
QQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLL
TFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFT

--------------------------------------------------------------
>8365_8365_14_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45221363_ENST00000389774_length(transcript)=1727nt_BP=721nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTATTGTTTGGGTGC
ATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTTTACATCCCTTA
ATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGAATCAGAATGGC
CGTACGATGAGAAGCTCCAGAGCCTGCACGAGGGCCGGACGCCGCCTCCCACCAAGACACCACCGCCGCGGCCCCCGCTGCCCACACAGC
AGTTTGGCGTCAGTCTGCAATACCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAG
AGAAAGGCCTGCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGC
CCGTGAACTTTGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCT
TCCAGGCCTACGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAG
AGCACAACTACGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACC
TGGCCTGTGTCTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAAC
TGCTGATCGAGTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAG
CCCCTTTGCAGGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGAC
GTCTCTAGTGTTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAA
AAATAACCAGCCATTAGATGAATTCAGAACCTTCTAATGAAAACTCCATGCCTCTGGTCCTTGGACTCTTGTCCATGGTTCCTGAGCTGT

>8365_8365_14_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45221363_ENST00000389774_length(amino acids)=423AA_BP=152
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVW
VHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPYDEKLQSLHEGRTPPPTKTPPPRPPLPT
QQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLL
TFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFT

--------------------------------------------------------------
>8365_8365_15_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45221363_ENST00000517296_length(transcript)=1649nt_BP=721nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTATTGTTTGGGTGC
ATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTTTACATCCCTTA
ATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGAATCAGAATGGC
CGTACGATGAGAAGCTCCAGAGCCTGCACGAGGGCCGGACGCCGCCTCCCACCAAGACACCACCGCCGCGGCCCCCGCTGCCCACACAGC
AGTTTGGCGTCAGTCTGCAATACCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAG
AGAAAGGCCTGCGCACCGAGGGCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGC
CCGTGAACTTTGACGACTACGGGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCT
TCCAGGCCTACGAGCAGATTCTCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAG
AGCACAACTACGTCGTCCTCCGCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACC
TGGCCTGTGTCTTCGGGCTGAATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAAC
TGCTGATCGAGTACTATGAAAAGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAG
CCCCTTTGCAGGAGGCTGTGCCACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGAC
GTCTCTAGTGTTGCGAACACTCTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAA

>8365_8365_15_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45221363_ENST00000517296_length(amino acids)=423AA_BP=152
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVW
VHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPYDEKLQSLHEGRTPPPTKTPPPRPPLPT
QQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLL
TFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFT

--------------------------------------------------------------
>8365_8365_16_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45241149_ENST00000336963_length(transcript)=1513nt_BP=721nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTATTGTTTGGGTGC
ATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTTTACATCCCTTA
ATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGAATCAGAATGGC
CCCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAGAGAAAGGCCTGCGCACCGAGG
GCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGCCCGTGAACTTTGACGACTACG
GGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCTTCCAGGCCTACGAGCAGATTC
TCGGGATCACCTGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGGCCTGTGTCTTCGGGCTGAATTTGATCTGGCCA
TCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGCTGATCGAGTACTATGAAAAGATCTTCAGCACC
CCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCCCTTTGCAGGAGGCTGTGCCACGGACACAAGCC
ACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTCTCTAGTGTTGCGAACACTCTGTATATTTCGAG
CTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAATAACCAGCCATTAGATGAATTCAGAACCTTCT

>8365_8365_16_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45241149_ENST00000336963_length(amino acids)=258AA_BP=152
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVW
VHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPLKDKNQGELIPPVLRFTVTYLREKGLRT

--------------------------------------------------------------
>8365_8365_17_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45241149_ENST00000356099_length(transcript)=1616nt_BP=721nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTATTGTTTGGGTGC
ATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTTTACATCCCTTA
ATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGAATCAGAATGGC
CCCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAGAGAAAGGCCTGCGCACCGAGG
GCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGCCCGTGAACTTTGACGACTACG
GGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCTTCCAGGCCTACGAGCAGATTC
TCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAGAGCACAACTACGTCGTCCTCC
GCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGGCCTGTGTCTTCGGGCTGA
ATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGCTGATCGAGTACTATGAAA
AGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCCCTTTGCAGGAGGCTGTGC
CACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTCTCTAGTGTTGCGAACACT
CTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAATAACCAGCCATTAGATGA

>8365_8365_17_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45241149_ENST00000356099_length(amino acids)=386AA_BP=152
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVW
VHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPLKDKNQGELIPPVLRFTVTYLREKGLRT
EGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVV
LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEA

--------------------------------------------------------------
>8365_8365_18_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45241149_ENST00000389773_length(transcript)=1616nt_BP=721nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTATTGTTTGGGTGC
ATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTTTACATCCCTTA
ATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGAATCAGAATGGC
CCCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAGAGAAAGGCCTGCGCACCGAGG
GCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGCCCGTGAACTTTGACGACTACG
GGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCTTCCAGGCCTACGAGCAGATTC
TCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAGAGCACAACTACGTCGTCCTCC
GCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGGCCTGTGTCTTCGGGCTGA
ATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGCTGATCGAGTACTATGAAA
AGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCCCTTTGCAGGAGGCTGTGC
CACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTCTCTAGTGTTGCGAACACT
CTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAATAACCAGCCATTAGATGA

>8365_8365_18_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45241149_ENST00000389773_length(amino acids)=386AA_BP=152
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVW
VHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPLKDKNQGELIPPVLRFTVTYLREKGLRT
EGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVV
LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEA

--------------------------------------------------------------
>8365_8365_19_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45241149_ENST00000389774_length(transcript)=1616nt_BP=721nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTATTGTTTGGGTGC
ATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTTTACATCCCTTA
ATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGAATCAGAATGGC
CCCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAGAGAAAGGCCTGCGCACCGAGG
GCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGCCCGTGAACTTTGACGACTACG
GGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCTTCCAGGCCTACGAGCAGATTC
TCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAGAGCACAACTACGTCGTCCTCC
GCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGGCCTGTGTCTTCGGGCTGA
ATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGCTGATCGAGTACTATGAAA
AGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCCCTTTGCAGGAGGCTGTGC
CACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTCTCTAGTGTTGCGAACACT
CTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAATAACCAGCCATTAGATGA

>8365_8365_19_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45241149_ENST00000389774_length(amino acids)=386AA_BP=152
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVW
VHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPLKDKNQGELIPPVLRFTVTYLREKGLRT
EGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVV
LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEA

--------------------------------------------------------------
>8365_8365_20_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45241149_ENST00000517296_length(transcript)=1538nt_BP=721nt
AGGCGGGACTTCCGCCGGCGCCCCCTCCCCCGCGGCGCCGTCTCCTCCTCCCGCCTGAGGCGAGTCTGGGCTCAGCCTAGAGCTCTCCGG
CGGCGGCGCAGCTTCAGGGCAGCGCGGGCTGCAGCGGCGGCGGCGGTTAGGGCTGTGTAGGGCGAGGCCTCCCCCTTCCTCCTCGCCATC
CTACTCCTCCCTCCTCGTCATCCTCCCCCTTCGTCCTCCTCGCCTTCCTCCTCCTCGTCAGGCTCGACCCAGCTGTGAGCGGCAAGATGG
CGGCGCCCAGGCCGCCGCCTGCCAGGCTGTCGGGCGTCATGGTGCCGGCGCCCATCCAAGACCTGGAGGCCCTGCGCGCGCTCACGGCGC
TCTTCAAAGAGCAGCGGAACCGGAACTTGGATACGATTGGTGTTGCTGTTGATTTGATTCTTCTGTTTCGTGAACTGCGAGTGGAACAGG
AATCTCTGTTGACAGCTTTTCGCTGTGGCCTGCAGTTTTTAGGCAACATTGCCTCACGGAATGAAGATTCCCAGTCTATTGTTTGGGTGC
ATGCTTTCCCAGAACTGTTTTTGTCTTGCTTAAATCATCCGGACAAAAAAATTGTTGCCTACTCTTCAATGATTTTGTTTACATCCCTTA
ATCATGAAAGAATGAAAGAACTGGAGGAGAACCTCAATATTGCAATTGATGTCATAGATGCTTACCAAAAACATCCTGAATCAGAATGGC
CCCTCAAAGACAAAAATCAAGGCGAACTCATCCCCCCTGTGCTGAGGTTCACAGTGACGTACCTGAGAGAGAAAGGCCTGCGCACCGAGG
GCCTGTTCCGGAGATCCGCCAGCGTGCAGACCGTCCGCGAGATCCAGAGGCTCTACAACCAAGGGAAGCCCGTGAACTTTGACGACTACG
GGGACATTCACATCCCTGCCGTGATCCTGAAGACCTTCCTGCGAGAGCTGCCCCAGCCGCTTCTGACCTTCCAGGCCTACGAGCAGATTC
TCGGGATCACCTGTGTGGAGAGCAGCCTGCGTGTCACTGGCTGCCGCCAGATCTTACGGAGCCTCCCAGAGCACAACTACGTCGTCCTCC
GCTACCTCATGGGCTTCCTGCATGCGGTGTCCCGGGAGAGCATCTTCAACAAAATGAACAGCTCTAACCTGGCCTGTGTCTTCGGGCTGA
ATTTGATCTGGCCATCCCAGGGGGTCTCCTCCCTGAGTGCCCTTGTGCCCCTGAACATGTTCACTGAACTGCTGATCGAGTACTATGAAA
AGATCTTCAGCACCCCGGAGGCACCTGGGGAGCACGGCCTGGCACCATGGGAACAGGGGAGCAGGGCAGCCCCTTTGCAGGAGGCTGTGC
CACGGACACAAGCCACGGGCCTCACCAAGCCTACCCTACCTCCGAGTCCCCTGATGGCAGCCAGAAGACGTCTCTAGTGTTGCGAACACT
CTGTATATTTCGAGCTACCTCCCACACCTGTCTGTGCACTTGTATGTTTTGTAAACTTGGCATCTGTAAAAATAACCAGCCATTAGATGA

>8365_8365_20_ATXN10-ARHGAP8_ATXN10_chr22_46098727_ENST00000381061_ARHGAP8_chr22_45241149_ENST00000517296_length(amino acids)=386AA_BP=152
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVW
VHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPLKDKNQGELIPPVLRFTVTYLREKGLRT
EGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVV
LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ATXN10-ARHGAP8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATXN10-ARHGAP8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATXN10-ARHGAP8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource