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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SLIRP-HTATSF1 (FusionGDB2 ID:83654)

Fusion Gene Summary for SLIRP-HTATSF1

Fusion gene summary

Fusion gene information	Fusion gene name: SLIRP-HTATSF1
	Fusion gene ID: 83654
		Hgene	Tgene
	Gene symbol	SLIRP	HTATSF1
	Gene ID	81892	27336
	Gene name	SRA stem-loop interacting RNA binding protein	HIV-1 Tat specific factor 1
	Synonyms	C14orf156\|DC50\|PD04872	TAT-SF1\|TATSF1\|dJ196E23.2
	Cytomap	14q24.3	Xq26.3
	Type of gene	protein-coding	protein-coding
	Description	SRA stem-loop-interacting RNA-binding protein, mitochondrial	HIV Tat-specific factor 1HIV TAT specific factor 1cofactor required for Tat activation of HIV-1 transcription
	Modification date	20200313	20200313
	UniProtAcc	.	O43719
	Ensembl transtripts involved in fusion gene	ENST00000238688, ENST00000557342, ENST00000557431, ENST00000557623,	ENST00000218364, ENST00000535601,
Fusion gene scores	* DoF score	10 X 5 X 3=150	4 X 4 X 3=48
	# samples	10	4
	** MAII score	log2(10/150*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SLIRP [Title/Abstract] AND HTATSF1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SLIRP(78182222)-HTATSF1(135591249), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across SLIRP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across HTATSF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-BR-A4PE	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+

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Fusion Gene ORF analysis for SLIRP-HTATSF1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000238688	ENST00000218364	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+
In-frame	ENST00000238688	ENST00000535601	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+
In-frame	ENST00000557342	ENST00000218364	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+
In-frame	ENST00000557342	ENST00000535601	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+
In-frame	ENST00000557431	ENST00000218364	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+
In-frame	ENST00000557431	ENST00000535601	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+
In-frame	ENST00000557623	ENST00000218364	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+
In-frame	ENST00000557623	ENST00000535601	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000557342	SLIRP	chr14	78182222	+	ENST00000535601	HTATSF1	chrX	135591249	+	2068	305	35	1738	567
ENST00000557342	SLIRP	chr14	78182222	+	ENST00000218364	HTATSF1	chrX	135591249	+	2072	305	35	1738	567
ENST00000238688	SLIRP	chr14	78182222	+	ENST00000535601	HTATSF1	chrX	135591249	+	2060	297	27	1730	567
ENST00000238688	SLIRP	chr14	78182222	+	ENST00000218364	HTATSF1	chrX	135591249	+	2064	297	27	1730	567
ENST00000557623	SLIRP	chr14	78182222	+	ENST00000535601	HTATSF1	chrX	135591249	+	2036	273	3	1706	567
ENST00000557623	SLIRP	chr14	78182222	+	ENST00000218364	HTATSF1	chrX	135591249	+	2040	273	3	1706	567
ENST00000557431	SLIRP	chr14	78182222	+	ENST00000535601	HTATSF1	chrX	135591249	+	2036	273	3	1706	567
ENST00000557431	SLIRP	chr14	78182222	+	ENST00000218364	HTATSF1	chrX	135591249	+	2040	273	3	1706	567

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000557342	ENST00000535601	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+	0.000928223	0.9990717
ENST00000557342	ENST00000218364	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+	0.000928368	0.9990716
ENST00000238688	ENST00000535601	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+	0.000942138	0.9990578
ENST00000238688	ENST00000218364	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+	0.000940997	0.999059
ENST00000557623	ENST00000535601	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+	0.000963179	0.9990368
ENST00000557623	ENST00000218364	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+	0.000961212	0.9990388
ENST00000557431	ENST00000535601	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+	0.000963179	0.9990368
ENST00000557431	ENST00000218364	SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+	0.000961212	0.9990388

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Fusion Genomic Features for SLIRP-HTATSF1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+	2.21E-05	0.9999778
SLIRP	chr14	78182222	+	HTATSF1	chrX	135591249	+	2.21E-05	0.9999778

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SLIRP-HTATSF1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:78182222/chrX:135591249)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	HTATSF1 O43719
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus. {ECO:0000269\|PubMed:10393184, ECO:0000269\|PubMed:10454543, ECO:0000269\|PubMed:10913173, ECO:0000269\|PubMed:11420046, ECO:0000269\|PubMed:11780068, ECO:0000269\|PubMed:15905670, ECO:0000269\|PubMed:8849451, ECO:0000269\|PubMed:9765201}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

HTATSF1

chr14:78182222

chrX:135591249

ENST00000218364

423_754

278

756.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

HTATSF1

chr14:78182222

chrX:135591249

ENST00000535601

423_754

278

756.0

Compositional bias

Note=Asp/Glu-rich (acidic)

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SLIRP

chr14:78182222

chrX:135591249

ENST00000238688

19_103

108.0

Domain

RRM

Hgene

SLIRP

chr14:78182222

chrX:135591249

ENST00000557342

19_103

110.0

Domain

RRM

Tgene

HTATSF1

chr14:78182222

chrX:135591249

ENST00000218364

228_234

278

756.0

Compositional bias

Note=Poly-Lys

Tgene

HTATSF1

chr14:78182222

chrX:135591249

ENST00000535601

228_234

278

756.0

Compositional bias

Note=Poly-Lys

Tgene

HTATSF1

chr14:78182222

chrX:135591249

ENST00000218364

133_218

278

756.0

Domain

RRM 1

Tgene

HTATSF1

chr14:78182222

chrX:135591249

ENST00000218364

264_349

278

756.0

Domain

RRM 2

Tgene

HTATSF1

chr14:78182222

chrX:135591249

ENST00000535601

133_218

278

756.0

Domain

RRM 1

Tgene

HTATSF1

chr14:78182222

chrX:135591249

ENST00000535601

264_349

278

756.0

Domain

RRM 2

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Fusion Gene Sequence for SLIRP-HTATSF1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>83654_83654_1_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000238688_HTATSF1_chrX_135591249_ENST00000218364_length(transcript)=2064nt_BP=297nt
GACCTCGGCTCGAGAAGGTGCTTTAGTCTGAAGATGGCGGCCTCAGCAGCGAGAGGTGCTGCGGCGCTGCGTAGAAGTATCAATCAGCCG
GTTGCTTTTGTGAGAAGAATTCCTTGGACTGCGGCGTCGAGTCAGCTGAAAGAACACTTTGCACAGTTCGGCCATGTCAGAAGGTGCATT
TTACCTTTTGACAAGGAGACTGGCTTTCACAGAGGTTTGGGTTGGGTTCAGTTTTCTTCAGAAGAAGGACTTCGGAATGCACTACAACAG
GAAAATCATATTATAGATGGAGTAAAGGATGATCCGTTGGTGCTGAATGAGATCAGAGAAGACCTTCGAGTAGAGTGTTCGAAGTTTGGA
CAAATTAGGAAACTCCTTCTCTTTGATAGGCACCCAGATGGTGTGGCCTCTGTGTCCTTTCGGGATCCAGAGGAAGCTGATTATTGTATT
CAGACTCTCGATGGAAGATGGTTTGGTGGCCGTCAAATCACTGCCCAGGCATGGGATGGGACTACAGATTATCAGGTGGAGGAAACCTCA
AGAGAAAGGGAGGAAAGGCTGAGAGGATGGGAGGCTTTCCTCAATGCTCCTGAGGCCAACAGAGGCCTTAGGCGTTCAGATTCTGTCTCT
GCTTCCGAAAGGGCAGGGCCTTCTAGAGCAAGGCATTTTTCAGAGCACCCCAGCACATCTAAAATGAATGCTCAAGAAACTGCAACTGGA
ATGGCGTTTGAAGAACCTATAGATGAGAAGAAGTTTGAAAAGACAGAAGATGGGGGAGAATTTGAAGAAGGTGCTTCTGAAAACAATGCT
AAGGAAAGTAGCCCCGAAAAAGAGGCTGAAGAAGGCTGCCCTGAAAAAGAATCTGAAGAGGGCTGCCCCAAAAGAGGGTTTGAAGGCAGC
TGCTCCCAAAAAGAGTCTGAAGAAGGCAATCCCGTAAGAGGATCTGAAGAGGATAGTCCTAAAAAAGAGTCTAAAAAGAAGACACTCAAA
AATGATTGTGAAGAGAATGGCCTTGCAAAGGAATCTGAAGATGACCTCAACAAGGAGTCTGAAGAGGAGGTTGGCCCCACAAAAGAGTCC
GAAGAAGATGACTCAGAGAAAGAGTCTGATGAAGACTGCTCTGAAAAACAGTCTGAAGATGGCTCCGAAAGAGAATTTGAAGAAAATGGT
CTCGAGAAAGATTTGGACGAGGAAGGTTCTGAAAAGGAGCTTCATGAAAATGTTCTTGACAAAGAGTTAGAAGAAAATGACTCTGAAAAC
TCCGAATTTGAAGATGACGGCTCTGAAAAAGTGTTAGATGAGGAAGGCTCTGAGAGAGAGTTTGACGAAGATTCAGATGAAAAGGAAGAA
GAGGAGGATACATATGAAAAAGTATTTGATGATGAGTCTGATGAGAAAGAGGATGAAGAATATGCAGATGAAAAGGGGCTTGAAGCTGCT
GATAAAAAGGCGGAAGAAGGTGATGCAGATGAAAAGCTGTTTGAAGAGTCAGATGACAAGGAAGATGAAGATGCAGATGGAAAGGAAGTT
GAAGATGCTGACGAAAAGTTGTTCGAAGATGATGATTCCAATGAGAAGTTGTTTGATGAGGAGGAAGATTCCAGTGAGAAGTTGTTTGAC
GATTCTGATGAGAGGGGGACTTTGGGTGGTTTTGGGAGTGTTGAAGAAGGGCCCCTATCCACTGGCAGCAGCTTTATTCTCAGTAGCGAT
GATGATGACGATGATATTTAATCCCTTAAACTTGCTTTTTAGGGAGAGTCCTCCATCTACATTTGCCTGTGCTTCAGGGTAATTACTAGT
AGTGTTACATGAACATGTGCATAGTGGTAGGATGCCATCAGATTAAAGCATTGAAGTGTTTCATTGTTACCTGTACCTAATGGTTTTAAA
TATATGTTAATTGATTGTTTAGTTAAAATGTCATAGTTACAATGCAAGTAAACTGGATACTTGTTCTTTTGTCAGATTTGTTAAATGCAT

>83654_83654_1_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000238688_HTATSF1_chrX_135591249_ENST00000218364_length(amino acids)=567AA_BP=90
MKMAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVK
DDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRG
WEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEA
EEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES
DEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVF
DDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLG

--------------------------------------------------------------
>83654_83654_2_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000238688_HTATSF1_chrX_135591249_ENST00000535601_length(transcript)=2060nt_BP=297nt
GACCTCGGCTCGAGAAGGTGCTTTAGTCTGAAGATGGCGGCCTCAGCAGCGAGAGGTGCTGCGGCGCTGCGTAGAAGTATCAATCAGCCG
GTTGCTTTTGTGAGAAGAATTCCTTGGACTGCGGCGTCGAGTCAGCTGAAAGAACACTTTGCACAGTTCGGCCATGTCAGAAGGTGCATT
TTACCTTTTGACAAGGAGACTGGCTTTCACAGAGGTTTGGGTTGGGTTCAGTTTTCTTCAGAAGAAGGACTTCGGAATGCACTACAACAG
GAAAATCATATTATAGATGGAGTAAAGGATGATCCGTTGGTGCTGAATGAGATCAGAGAAGACCTTCGAGTAGAGTGTTCGAAGTTTGGA
CAAATTAGGAAACTCCTTCTCTTTGATAGGCACCCAGATGGTGTGGCCTCTGTGTCCTTTCGGGATCCAGAGGAAGCTGATTATTGTATT
CAGACTCTCGATGGAAGATGGTTTGGTGGCCGTCAAATCACTGCCCAGGCATGGGATGGGACTACAGATTATCAGGTGGAGGAAACCTCA
AGAGAAAGGGAGGAAAGGCTGAGAGGATGGGAGGCTTTCCTCAATGCTCCTGAGGCCAACAGAGGCCTTAGGCGTTCAGATTCTGTCTCT
GCTTCCGAAAGGGCAGGGCCTTCTAGAGCAAGGCATTTTTCAGAGCACCCCAGCACATCTAAAATGAATGCTCAAGAAACTGCAACTGGA
ATGGCGTTTGAAGAACCTATAGATGAGAAGAAGTTTGAAAAGACAGAAGATGGGGGAGAATTTGAAGAAGGTGCTTCTGAAAACAATGCT
AAGGAAAGTAGCCCCGAAAAAGAGGCTGAAGAAGGCTGCCCTGAAAAAGAATCTGAAGAGGGCTGCCCCAAAAGAGGGTTTGAAGGCAGC
TGCTCCCAAAAAGAGTCTGAAGAAGGCAATCCCGTAAGAGGATCTGAAGAGGATAGTCCTAAAAAAGAGTCTAAAAAGAAGACACTCAAA
AATGATTGTGAAGAGAATGGCCTTGCAAAGGAATCTGAAGATGACCTCAACAAGGAGTCTGAAGAGGAGGTTGGCCCCACAAAAGAGTCC
GAAGAAGATGACTCAGAGAAAGAGTCTGATGAAGACTGCTCTGAAAAACAGTCTGAAGATGGCTCCGAAAGAGAATTTGAAGAAAATGGT
CTCGAGAAAGATTTGGACGAGGAAGGTTCTGAAAAGGAGCTTCATGAAAATGTTCTTGACAAAGAGTTAGAAGAAAATGACTCTGAAAAC
TCCGAATTTGAAGATGACGGCTCTGAAAAAGTGTTAGATGAGGAAGGCTCTGAGAGAGAGTTTGACGAAGATTCAGATGAAAAGGAAGAA
GAGGAGGATACATATGAAAAAGTATTTGATGATGAGTCTGATGAGAAAGAGGATGAAGAATATGCAGATGAAAAGGGGCTTGAAGCTGCT
GATAAAAAGGCGGAAGAAGGTGATGCAGATGAAAAGCTGTTTGAAGAGTCAGATGACAAGGAAGATGAAGATGCAGATGGAAAGGAAGTT
GAAGATGCTGACGAAAAGTTGTTCGAAGATGATGATTCCAATGAGAAGTTGTTTGATGAGGAGGAAGATTCCAGTGAGAAGTTGTTTGAC
GATTCTGATGAGAGGGGGACTTTGGGTGGTTTTGGGAGTGTTGAAGAAGGGCCCCTATCCACTGGCAGCAGCTTTATTCTCAGTAGCGAT
GATGATGACGATGATATTTAATCCCTTAAACTTGCTTTTTAGGGAGAGTCCTCCATCTACATTTGCCTGTGCTTCAGGGTAATTACTAGT
AGTGTTACATGAACATGTGCATAGTGGTAGGATGCCATCAGATTAAAGCATTGAAGTGTTTCATTGTTACCTGTACCTAATGGTTTTAAA
TATATGTTAATTGATTGTTTAGTTAAAATGTCATAGTTACAATGCAAGTAAACTGGATACTTGTTCTTTTGTCAGATTTGTTAAATGCAT

>83654_83654_2_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000238688_HTATSF1_chrX_135591249_ENST00000535601_length(amino acids)=567AA_BP=90
MKMAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVK
DDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRG
WEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEA
EEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES
DEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVF
DDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLG

--------------------------------------------------------------
>83654_83654_3_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557342_HTATSF1_chrX_135591249_ENST00000218364_length(transcript)=2072nt_BP=305nt
GGGGCCGCGACCTCGGCTCGAGAAGGTGCTTTAGTCTGAAGATGGCGGCCTCAGCAGCGAGAGGTGCTGCGGCGCTGCGTAGAAGTATCA
ATCAGCCGGTTGCTTTTGTGAGAAGAATTCCTTGGACTGCGGCGTCGAGTCAGCTGAAAGAACACTTTGCACAGTTCGGCCATGTCAGAA
GGTGCATTTTACCTTTTGACAAGGAGACTGGCTTTCACAGAGGTTTGGGTTGGGTTCAGTTTTCTTCAGAAGAAGGACTTCGGAATGCAC
TACAACAGGAAAATCATATTATAGATGGAGTAAAGGATGATCCGTTGGTGCTGAATGAGATCAGAGAAGACCTTCGAGTAGAGTGTTCGA
AGTTTGGACAAATTAGGAAACTCCTTCTCTTTGATAGGCACCCAGATGGTGTGGCCTCTGTGTCCTTTCGGGATCCAGAGGAAGCTGATT
ATTGTATTCAGACTCTCGATGGAAGATGGTTTGGTGGCCGTCAAATCACTGCCCAGGCATGGGATGGGACTACAGATTATCAGGTGGAGG
AAACCTCAAGAGAAAGGGAGGAAAGGCTGAGAGGATGGGAGGCTTTCCTCAATGCTCCTGAGGCCAACAGAGGCCTTAGGCGTTCAGATT
CTGTCTCTGCTTCCGAAAGGGCAGGGCCTTCTAGAGCAAGGCATTTTTCAGAGCACCCCAGCACATCTAAAATGAATGCTCAAGAAACTG
CAACTGGAATGGCGTTTGAAGAACCTATAGATGAGAAGAAGTTTGAAAAGACAGAAGATGGGGGAGAATTTGAAGAAGGTGCTTCTGAAA
ACAATGCTAAGGAAAGTAGCCCCGAAAAAGAGGCTGAAGAAGGCTGCCCTGAAAAAGAATCTGAAGAGGGCTGCCCCAAAAGAGGGTTTG
AAGGCAGCTGCTCCCAAAAAGAGTCTGAAGAAGGCAATCCCGTAAGAGGATCTGAAGAGGATAGTCCTAAAAAAGAGTCTAAAAAGAAGA
CACTCAAAAATGATTGTGAAGAGAATGGCCTTGCAAAGGAATCTGAAGATGACCTCAACAAGGAGTCTGAAGAGGAGGTTGGCCCCACAA
AAGAGTCCGAAGAAGATGACTCAGAGAAAGAGTCTGATGAAGACTGCTCTGAAAAACAGTCTGAAGATGGCTCCGAAAGAGAATTTGAAG
AAAATGGTCTCGAGAAAGATTTGGACGAGGAAGGTTCTGAAAAGGAGCTTCATGAAAATGTTCTTGACAAAGAGTTAGAAGAAAATGACT
CTGAAAACTCCGAATTTGAAGATGACGGCTCTGAAAAAGTGTTAGATGAGGAAGGCTCTGAGAGAGAGTTTGACGAAGATTCAGATGAAA
AGGAAGAAGAGGAGGATACATATGAAAAAGTATTTGATGATGAGTCTGATGAGAAAGAGGATGAAGAATATGCAGATGAAAAGGGGCTTG
AAGCTGCTGATAAAAAGGCGGAAGAAGGTGATGCAGATGAAAAGCTGTTTGAAGAGTCAGATGACAAGGAAGATGAAGATGCAGATGGAA
AGGAAGTTGAAGATGCTGACGAAAAGTTGTTCGAAGATGATGATTCCAATGAGAAGTTGTTTGATGAGGAGGAAGATTCCAGTGAGAAGT
TGTTTGACGATTCTGATGAGAGGGGGACTTTGGGTGGTTTTGGGAGTGTTGAAGAAGGGCCCCTATCCACTGGCAGCAGCTTTATTCTCA
GTAGCGATGATGATGACGATGATATTTAATCCCTTAAACTTGCTTTTTAGGGAGAGTCCTCCATCTACATTTGCCTGTGCTTCAGGGTAA
TTACTAGTAGTGTTACATGAACATGTGCATAGTGGTAGGATGCCATCAGATTAAAGCATTGAAGTGTTTCATTGTTACCTGTACCTAATG
GTTTTAAATATATGTTAATTGATTGTTTAGTTAAAATGTCATAGTTACAATGCAAGTAAACTGGATACTTGTTCTTTTGTCAGATTTGTT
AAATGCATGCAGAATAATATTTTTAAGAGTATTGATTGAAGTTTGTGATATTCATCAATAAAAATGAGTTGATAATATGCAGAAACTGAA

>83654_83654_3_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557342_HTATSF1_chrX_135591249_ENST00000218364_length(amino acids)=567AA_BP=90
MKMAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVK
DDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRG
WEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEA
EEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES
DEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVF
DDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLG

--------------------------------------------------------------
>83654_83654_4_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557342_HTATSF1_chrX_135591249_ENST00000535601_length(transcript)=2068nt_BP=305nt
GGGGCCGCGACCTCGGCTCGAGAAGGTGCTTTAGTCTGAAGATGGCGGCCTCAGCAGCGAGAGGTGCTGCGGCGCTGCGTAGAAGTATCA
ATCAGCCGGTTGCTTTTGTGAGAAGAATTCCTTGGACTGCGGCGTCGAGTCAGCTGAAAGAACACTTTGCACAGTTCGGCCATGTCAGAA
GGTGCATTTTACCTTTTGACAAGGAGACTGGCTTTCACAGAGGTTTGGGTTGGGTTCAGTTTTCTTCAGAAGAAGGACTTCGGAATGCAC
TACAACAGGAAAATCATATTATAGATGGAGTAAAGGATGATCCGTTGGTGCTGAATGAGATCAGAGAAGACCTTCGAGTAGAGTGTTCGA
AGTTTGGACAAATTAGGAAACTCCTTCTCTTTGATAGGCACCCAGATGGTGTGGCCTCTGTGTCCTTTCGGGATCCAGAGGAAGCTGATT
ATTGTATTCAGACTCTCGATGGAAGATGGTTTGGTGGCCGTCAAATCACTGCCCAGGCATGGGATGGGACTACAGATTATCAGGTGGAGG
AAACCTCAAGAGAAAGGGAGGAAAGGCTGAGAGGATGGGAGGCTTTCCTCAATGCTCCTGAGGCCAACAGAGGCCTTAGGCGTTCAGATT
CTGTCTCTGCTTCCGAAAGGGCAGGGCCTTCTAGAGCAAGGCATTTTTCAGAGCACCCCAGCACATCTAAAATGAATGCTCAAGAAACTG
CAACTGGAATGGCGTTTGAAGAACCTATAGATGAGAAGAAGTTTGAAAAGACAGAAGATGGGGGAGAATTTGAAGAAGGTGCTTCTGAAA
ACAATGCTAAGGAAAGTAGCCCCGAAAAAGAGGCTGAAGAAGGCTGCCCTGAAAAAGAATCTGAAGAGGGCTGCCCCAAAAGAGGGTTTG
AAGGCAGCTGCTCCCAAAAAGAGTCTGAAGAAGGCAATCCCGTAAGAGGATCTGAAGAGGATAGTCCTAAAAAAGAGTCTAAAAAGAAGA
CACTCAAAAATGATTGTGAAGAGAATGGCCTTGCAAAGGAATCTGAAGATGACCTCAACAAGGAGTCTGAAGAGGAGGTTGGCCCCACAA
AAGAGTCCGAAGAAGATGACTCAGAGAAAGAGTCTGATGAAGACTGCTCTGAAAAACAGTCTGAAGATGGCTCCGAAAGAGAATTTGAAG
AAAATGGTCTCGAGAAAGATTTGGACGAGGAAGGTTCTGAAAAGGAGCTTCATGAAAATGTTCTTGACAAAGAGTTAGAAGAAAATGACT
CTGAAAACTCCGAATTTGAAGATGACGGCTCTGAAAAAGTGTTAGATGAGGAAGGCTCTGAGAGAGAGTTTGACGAAGATTCAGATGAAA
AGGAAGAAGAGGAGGATACATATGAAAAAGTATTTGATGATGAGTCTGATGAGAAAGAGGATGAAGAATATGCAGATGAAAAGGGGCTTG
AAGCTGCTGATAAAAAGGCGGAAGAAGGTGATGCAGATGAAAAGCTGTTTGAAGAGTCAGATGACAAGGAAGATGAAGATGCAGATGGAA
AGGAAGTTGAAGATGCTGACGAAAAGTTGTTCGAAGATGATGATTCCAATGAGAAGTTGTTTGATGAGGAGGAAGATTCCAGTGAGAAGT
TGTTTGACGATTCTGATGAGAGGGGGACTTTGGGTGGTTTTGGGAGTGTTGAAGAAGGGCCCCTATCCACTGGCAGCAGCTTTATTCTCA
GTAGCGATGATGATGACGATGATATTTAATCCCTTAAACTTGCTTTTTAGGGAGAGTCCTCCATCTACATTTGCCTGTGCTTCAGGGTAA
TTACTAGTAGTGTTACATGAACATGTGCATAGTGGTAGGATGCCATCAGATTAAAGCATTGAAGTGTTTCATTGTTACCTGTACCTAATG
GTTTTAAATATATGTTAATTGATTGTTTAGTTAAAATGTCATAGTTACAATGCAAGTAAACTGGATACTTGTTCTTTTGTCAGATTTGTT

>83654_83654_4_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557342_HTATSF1_chrX_135591249_ENST00000535601_length(amino acids)=567AA_BP=90
MKMAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVK
DDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRG
WEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEA
EEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES
DEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVF
DDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLG

--------------------------------------------------------------
>83654_83654_5_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557431_HTATSF1_chrX_135591249_ENST00000218364_length(transcript)=2040nt_BP=273nt
AGTCTGAAGATGGCGGCCTCAGCAGCGAGAGGTGCTGCGGCGCTGCGTAGAAGTATCAATCAGCCGGTTGCTTTTGTGAGAAGAATTCCT
TGGACTGCGGCGTCGAGTCAGCTGAAAGAACACTTTGCACAGTTCGGCCATGTCAGAAGGTGCATTTTACCTTTTGACAAGGAGACTGGC
TTTCACAGAGGTTTGGGTTGGGTTCAGTTTTCTTCAGAAGAAGGACTTCGGAATGCACTACAACAGGAAAATCATATTATAGATGGAGTA
AAGGATGATCCGTTGGTGCTGAATGAGATCAGAGAAGACCTTCGAGTAGAGTGTTCGAAGTTTGGACAAATTAGGAAACTCCTTCTCTTT
GATAGGCACCCAGATGGTGTGGCCTCTGTGTCCTTTCGGGATCCAGAGGAAGCTGATTATTGTATTCAGACTCTCGATGGAAGATGGTTT
GGTGGCCGTCAAATCACTGCCCAGGCATGGGATGGGACTACAGATTATCAGGTGGAGGAAACCTCAAGAGAAAGGGAGGAAAGGCTGAGA
GGATGGGAGGCTTTCCTCAATGCTCCTGAGGCCAACAGAGGCCTTAGGCGTTCAGATTCTGTCTCTGCTTCCGAAAGGGCAGGGCCTTCT
AGAGCAAGGCATTTTTCAGAGCACCCCAGCACATCTAAAATGAATGCTCAAGAAACTGCAACTGGAATGGCGTTTGAAGAACCTATAGAT
GAGAAGAAGTTTGAAAAGACAGAAGATGGGGGAGAATTTGAAGAAGGTGCTTCTGAAAACAATGCTAAGGAAAGTAGCCCCGAAAAAGAG
GCTGAAGAAGGCTGCCCTGAAAAAGAATCTGAAGAGGGCTGCCCCAAAAGAGGGTTTGAAGGCAGCTGCTCCCAAAAAGAGTCTGAAGAA
GGCAATCCCGTAAGAGGATCTGAAGAGGATAGTCCTAAAAAAGAGTCTAAAAAGAAGACACTCAAAAATGATTGTGAAGAGAATGGCCTT
GCAAAGGAATCTGAAGATGACCTCAACAAGGAGTCTGAAGAGGAGGTTGGCCCCACAAAAGAGTCCGAAGAAGATGACTCAGAGAAAGAG
TCTGATGAAGACTGCTCTGAAAAACAGTCTGAAGATGGCTCCGAAAGAGAATTTGAAGAAAATGGTCTCGAGAAAGATTTGGACGAGGAA
GGTTCTGAAAAGGAGCTTCATGAAAATGTTCTTGACAAAGAGTTAGAAGAAAATGACTCTGAAAACTCCGAATTTGAAGATGACGGCTCT
GAAAAAGTGTTAGATGAGGAAGGCTCTGAGAGAGAGTTTGACGAAGATTCAGATGAAAAGGAAGAAGAGGAGGATACATATGAAAAAGTA
TTTGATGATGAGTCTGATGAGAAAGAGGATGAAGAATATGCAGATGAAAAGGGGCTTGAAGCTGCTGATAAAAAGGCGGAAGAAGGTGAT
GCAGATGAAAAGCTGTTTGAAGAGTCAGATGACAAGGAAGATGAAGATGCAGATGGAAAGGAAGTTGAAGATGCTGACGAAAAGTTGTTC
GAAGATGATGATTCCAATGAGAAGTTGTTTGATGAGGAGGAAGATTCCAGTGAGAAGTTGTTTGACGATTCTGATGAGAGGGGGACTTTG
GGTGGTTTTGGGAGTGTTGAAGAAGGGCCCCTATCCACTGGCAGCAGCTTTATTCTCAGTAGCGATGATGATGACGATGATATTTAATCC
CTTAAACTTGCTTTTTAGGGAGAGTCCTCCATCTACATTTGCCTGTGCTTCAGGGTAATTACTAGTAGTGTTACATGAACATGTGCATAG
TGGTAGGATGCCATCAGATTAAAGCATTGAAGTGTTTCATTGTTACCTGTACCTAATGGTTTTAAATATATGTTAATTGATTGTTTAGTT
AAAATGTCATAGTTACAATGCAAGTAAACTGGATACTTGTTCTTTTGTCAGATTTGTTAAATGCATGCAGAATAATATTTTTAAGAGTAT

>83654_83654_5_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557431_HTATSF1_chrX_135591249_ENST00000218364_length(amino acids)=567AA_BP=90
MKMAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVK
DDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRG
WEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEA
EEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES
DEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVF
DDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLG

--------------------------------------------------------------
>83654_83654_6_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557431_HTATSF1_chrX_135591249_ENST00000535601_length(transcript)=2036nt_BP=273nt
AGTCTGAAGATGGCGGCCTCAGCAGCGAGAGGTGCTGCGGCGCTGCGTAGAAGTATCAATCAGCCGGTTGCTTTTGTGAGAAGAATTCCT
TGGACTGCGGCGTCGAGTCAGCTGAAAGAACACTTTGCACAGTTCGGCCATGTCAGAAGGTGCATTTTACCTTTTGACAAGGAGACTGGC
TTTCACAGAGGTTTGGGTTGGGTTCAGTTTTCTTCAGAAGAAGGACTTCGGAATGCACTACAACAGGAAAATCATATTATAGATGGAGTA
AAGGATGATCCGTTGGTGCTGAATGAGATCAGAGAAGACCTTCGAGTAGAGTGTTCGAAGTTTGGACAAATTAGGAAACTCCTTCTCTTT
GATAGGCACCCAGATGGTGTGGCCTCTGTGTCCTTTCGGGATCCAGAGGAAGCTGATTATTGTATTCAGACTCTCGATGGAAGATGGTTT
GGTGGCCGTCAAATCACTGCCCAGGCATGGGATGGGACTACAGATTATCAGGTGGAGGAAACCTCAAGAGAAAGGGAGGAAAGGCTGAGA
GGATGGGAGGCTTTCCTCAATGCTCCTGAGGCCAACAGAGGCCTTAGGCGTTCAGATTCTGTCTCTGCTTCCGAAAGGGCAGGGCCTTCT
AGAGCAAGGCATTTTTCAGAGCACCCCAGCACATCTAAAATGAATGCTCAAGAAACTGCAACTGGAATGGCGTTTGAAGAACCTATAGAT
GAGAAGAAGTTTGAAAAGACAGAAGATGGGGGAGAATTTGAAGAAGGTGCTTCTGAAAACAATGCTAAGGAAAGTAGCCCCGAAAAAGAG
GCTGAAGAAGGCTGCCCTGAAAAAGAATCTGAAGAGGGCTGCCCCAAAAGAGGGTTTGAAGGCAGCTGCTCCCAAAAAGAGTCTGAAGAA
GGCAATCCCGTAAGAGGATCTGAAGAGGATAGTCCTAAAAAAGAGTCTAAAAAGAAGACACTCAAAAATGATTGTGAAGAGAATGGCCTT
GCAAAGGAATCTGAAGATGACCTCAACAAGGAGTCTGAAGAGGAGGTTGGCCCCACAAAAGAGTCCGAAGAAGATGACTCAGAGAAAGAG
TCTGATGAAGACTGCTCTGAAAAACAGTCTGAAGATGGCTCCGAAAGAGAATTTGAAGAAAATGGTCTCGAGAAAGATTTGGACGAGGAA
GGTTCTGAAAAGGAGCTTCATGAAAATGTTCTTGACAAAGAGTTAGAAGAAAATGACTCTGAAAACTCCGAATTTGAAGATGACGGCTCT
GAAAAAGTGTTAGATGAGGAAGGCTCTGAGAGAGAGTTTGACGAAGATTCAGATGAAAAGGAAGAAGAGGAGGATACATATGAAAAAGTA
TTTGATGATGAGTCTGATGAGAAAGAGGATGAAGAATATGCAGATGAAAAGGGGCTTGAAGCTGCTGATAAAAAGGCGGAAGAAGGTGAT
GCAGATGAAAAGCTGTTTGAAGAGTCAGATGACAAGGAAGATGAAGATGCAGATGGAAAGGAAGTTGAAGATGCTGACGAAAAGTTGTTC
GAAGATGATGATTCCAATGAGAAGTTGTTTGATGAGGAGGAAGATTCCAGTGAGAAGTTGTTTGACGATTCTGATGAGAGGGGGACTTTG
GGTGGTTTTGGGAGTGTTGAAGAAGGGCCCCTATCCACTGGCAGCAGCTTTATTCTCAGTAGCGATGATGATGACGATGATATTTAATCC
CTTAAACTTGCTTTTTAGGGAGAGTCCTCCATCTACATTTGCCTGTGCTTCAGGGTAATTACTAGTAGTGTTACATGAACATGTGCATAG
TGGTAGGATGCCATCAGATTAAAGCATTGAAGTGTTTCATTGTTACCTGTACCTAATGGTTTTAAATATATGTTAATTGATTGTTTAGTT
AAAATGTCATAGTTACAATGCAAGTAAACTGGATACTTGTTCTTTTGTCAGATTTGTTAAATGCATGCAGAATAATATTTTTAAGAGTAT

>83654_83654_6_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557431_HTATSF1_chrX_135591249_ENST00000535601_length(amino acids)=567AA_BP=90
MKMAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVK
DDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRG
WEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEA
EEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES
DEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVF
DDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLG

--------------------------------------------------------------
>83654_83654_7_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557623_HTATSF1_chrX_135591249_ENST00000218364_length(transcript)=2040nt_BP=273nt
AGTCTGAAGATGGCGGCCTCAGCAGCGAGAGGTGCTGCGGCGCTGCGTAGAAGTATCAATCAGCCGGTTGCTTTTGTGAGAAGAATTCCT
TGGACTGCGGCGTCGAGTCAGCTGAAAGAACACTTTGCACAGTTCGGCCATGTCAGAAGGTGCATTTTACCTTTTGACAAGGAGACTGGC
TTTCACAGAGGTTTGGGTTGGGTTCAGTTTTCTTCAGAAGAAGGACTTCGGAATGCACTACAACAGGAAAATCATATTATAGATGGAGTA
AAGGATGATCCGTTGGTGCTGAATGAGATCAGAGAAGACCTTCGAGTAGAGTGTTCGAAGTTTGGACAAATTAGGAAACTCCTTCTCTTT
GATAGGCACCCAGATGGTGTGGCCTCTGTGTCCTTTCGGGATCCAGAGGAAGCTGATTATTGTATTCAGACTCTCGATGGAAGATGGTTT
GGTGGCCGTCAAATCACTGCCCAGGCATGGGATGGGACTACAGATTATCAGGTGGAGGAAACCTCAAGAGAAAGGGAGGAAAGGCTGAGA
GGATGGGAGGCTTTCCTCAATGCTCCTGAGGCCAACAGAGGCCTTAGGCGTTCAGATTCTGTCTCTGCTTCCGAAAGGGCAGGGCCTTCT
AGAGCAAGGCATTTTTCAGAGCACCCCAGCACATCTAAAATGAATGCTCAAGAAACTGCAACTGGAATGGCGTTTGAAGAACCTATAGAT
GAGAAGAAGTTTGAAAAGACAGAAGATGGGGGAGAATTTGAAGAAGGTGCTTCTGAAAACAATGCTAAGGAAAGTAGCCCCGAAAAAGAG
GCTGAAGAAGGCTGCCCTGAAAAAGAATCTGAAGAGGGCTGCCCCAAAAGAGGGTTTGAAGGCAGCTGCTCCCAAAAAGAGTCTGAAGAA
GGCAATCCCGTAAGAGGATCTGAAGAGGATAGTCCTAAAAAAGAGTCTAAAAAGAAGACACTCAAAAATGATTGTGAAGAGAATGGCCTT
GCAAAGGAATCTGAAGATGACCTCAACAAGGAGTCTGAAGAGGAGGTTGGCCCCACAAAAGAGTCCGAAGAAGATGACTCAGAGAAAGAG
TCTGATGAAGACTGCTCTGAAAAACAGTCTGAAGATGGCTCCGAAAGAGAATTTGAAGAAAATGGTCTCGAGAAAGATTTGGACGAGGAA
GGTTCTGAAAAGGAGCTTCATGAAAATGTTCTTGACAAAGAGTTAGAAGAAAATGACTCTGAAAACTCCGAATTTGAAGATGACGGCTCT
GAAAAAGTGTTAGATGAGGAAGGCTCTGAGAGAGAGTTTGACGAAGATTCAGATGAAAAGGAAGAAGAGGAGGATACATATGAAAAAGTA
TTTGATGATGAGTCTGATGAGAAAGAGGATGAAGAATATGCAGATGAAAAGGGGCTTGAAGCTGCTGATAAAAAGGCGGAAGAAGGTGAT
GCAGATGAAAAGCTGTTTGAAGAGTCAGATGACAAGGAAGATGAAGATGCAGATGGAAAGGAAGTTGAAGATGCTGACGAAAAGTTGTTC
GAAGATGATGATTCCAATGAGAAGTTGTTTGATGAGGAGGAAGATTCCAGTGAGAAGTTGTTTGACGATTCTGATGAGAGGGGGACTTTG
GGTGGTTTTGGGAGTGTTGAAGAAGGGCCCCTATCCACTGGCAGCAGCTTTATTCTCAGTAGCGATGATGATGACGATGATATTTAATCC
CTTAAACTTGCTTTTTAGGGAGAGTCCTCCATCTACATTTGCCTGTGCTTCAGGGTAATTACTAGTAGTGTTACATGAACATGTGCATAG
TGGTAGGATGCCATCAGATTAAAGCATTGAAGTGTTTCATTGTTACCTGTACCTAATGGTTTTAAATATATGTTAATTGATTGTTTAGTT
AAAATGTCATAGTTACAATGCAAGTAAACTGGATACTTGTTCTTTTGTCAGATTTGTTAAATGCATGCAGAATAATATTTTTAAGAGTAT

>83654_83654_7_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557623_HTATSF1_chrX_135591249_ENST00000218364_length(amino acids)=567AA_BP=90
MKMAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVK
DDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRG
WEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEA
EEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES
DEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVF
DDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLG

--------------------------------------------------------------
>83654_83654_8_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557623_HTATSF1_chrX_135591249_ENST00000535601_length(transcript)=2036nt_BP=273nt
AGTCTGAAGATGGCGGCCTCAGCAGCGAGAGGTGCTGCGGCGCTGCGTAGAAGTATCAATCAGCCGGTTGCTTTTGTGAGAAGAATTCCT
TGGACTGCGGCGTCGAGTCAGCTGAAAGAACACTTTGCACAGTTCGGCCATGTCAGAAGGTGCATTTTACCTTTTGACAAGGAGACTGGC
TTTCACAGAGGTTTGGGTTGGGTTCAGTTTTCTTCAGAAGAAGGACTTCGGAATGCACTACAACAGGAAAATCATATTATAGATGGAGTA
AAGGATGATCCGTTGGTGCTGAATGAGATCAGAGAAGACCTTCGAGTAGAGTGTTCGAAGTTTGGACAAATTAGGAAACTCCTTCTCTTT
GATAGGCACCCAGATGGTGTGGCCTCTGTGTCCTTTCGGGATCCAGAGGAAGCTGATTATTGTATTCAGACTCTCGATGGAAGATGGTTT
GGTGGCCGTCAAATCACTGCCCAGGCATGGGATGGGACTACAGATTATCAGGTGGAGGAAACCTCAAGAGAAAGGGAGGAAAGGCTGAGA
GGATGGGAGGCTTTCCTCAATGCTCCTGAGGCCAACAGAGGCCTTAGGCGTTCAGATTCTGTCTCTGCTTCCGAAAGGGCAGGGCCTTCT
AGAGCAAGGCATTTTTCAGAGCACCCCAGCACATCTAAAATGAATGCTCAAGAAACTGCAACTGGAATGGCGTTTGAAGAACCTATAGAT
GAGAAGAAGTTTGAAAAGACAGAAGATGGGGGAGAATTTGAAGAAGGTGCTTCTGAAAACAATGCTAAGGAAAGTAGCCCCGAAAAAGAG
GCTGAAGAAGGCTGCCCTGAAAAAGAATCTGAAGAGGGCTGCCCCAAAAGAGGGTTTGAAGGCAGCTGCTCCCAAAAAGAGTCTGAAGAA
GGCAATCCCGTAAGAGGATCTGAAGAGGATAGTCCTAAAAAAGAGTCTAAAAAGAAGACACTCAAAAATGATTGTGAAGAGAATGGCCTT
GCAAAGGAATCTGAAGATGACCTCAACAAGGAGTCTGAAGAGGAGGTTGGCCCCACAAAAGAGTCCGAAGAAGATGACTCAGAGAAAGAG
TCTGATGAAGACTGCTCTGAAAAACAGTCTGAAGATGGCTCCGAAAGAGAATTTGAAGAAAATGGTCTCGAGAAAGATTTGGACGAGGAA
GGTTCTGAAAAGGAGCTTCATGAAAATGTTCTTGACAAAGAGTTAGAAGAAAATGACTCTGAAAACTCCGAATTTGAAGATGACGGCTCT
GAAAAAGTGTTAGATGAGGAAGGCTCTGAGAGAGAGTTTGACGAAGATTCAGATGAAAAGGAAGAAGAGGAGGATACATATGAAAAAGTA
TTTGATGATGAGTCTGATGAGAAAGAGGATGAAGAATATGCAGATGAAAAGGGGCTTGAAGCTGCTGATAAAAAGGCGGAAGAAGGTGAT
GCAGATGAAAAGCTGTTTGAAGAGTCAGATGACAAGGAAGATGAAGATGCAGATGGAAAGGAAGTTGAAGATGCTGACGAAAAGTTGTTC
GAAGATGATGATTCCAATGAGAAGTTGTTTGATGAGGAGGAAGATTCCAGTGAGAAGTTGTTTGACGATTCTGATGAGAGGGGGACTTTG
GGTGGTTTTGGGAGTGTTGAAGAAGGGCCCCTATCCACTGGCAGCAGCTTTATTCTCAGTAGCGATGATGATGACGATGATATTTAATCC
CTTAAACTTGCTTTTTAGGGAGAGTCCTCCATCTACATTTGCCTGTGCTTCAGGGTAATTACTAGTAGTGTTACATGAACATGTGCATAG
TGGTAGGATGCCATCAGATTAAAGCATTGAAGTGTTTCATTGTTACCTGTACCTAATGGTTTTAAATATATGTTAATTGATTGTTTAGTT
AAAATGTCATAGTTACAATGCAAGTAAACTGGATACTTGTTCTTTTGTCAGATTTGTTAAATGCATGCAGAATAATATTTTTAAGAGTAT

>83654_83654_8_SLIRP-HTATSF1_SLIRP_chr14_78182222_ENST00000557623_HTATSF1_chrX_135591249_ENST00000535601_length(amino acids)=567AA_BP=90
MKMAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVK
DDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRG
WEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEA
EEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES
DEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVF
DDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLG

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SLIRP-HTATSF1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for SLIRP-HTATSF1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for SLIRP-HTATSF1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source