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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SLIT3-ITPR2 (FusionGDB2 ID:83673)

Fusion Gene Summary for SLIT3-ITPR2

check button Fusion gene summary
Fusion gene informationFusion gene name: SLIT3-ITPR2
Fusion gene ID: 83673
HgeneTgene
Gene symbol

SLIT3

ITPR2

Gene ID

6586

3709

Gene nameslit guidance ligand 3inositol 1,4,5-trisphosphate receptor type 2
SynonymsMEGF5|SLIL2|SLIT1|Slit-3|slit2ANHD|CFAP48|INSP3R2|IP3R2
Cytomap

5q34-q35.1

12p11.23

Type of geneprotein-codingprotein-coding
Descriptionslit homolog 3 proteinmultiple EGF-like domains protein 5multiple epidermal growth factor-like domains protein 5slit homolog 3inositol 1,4,5-trisphosphate receptor type 2IP3 receptorIP3R 2cilia and flagella associated protein 48type 2 InsP3 receptor
Modification date2020031320200313
UniProtAcc.

Q14571

Ensembl transtripts involved in fusion geneENST00000332966, ENST00000404867, 
ENST00000519560, ENST00000521130, 
ENST00000242737, ENST00000545902, 
ENST00000381340, 
Fusion gene scores* DoF score9 X 6 X 5=27027 X 21 X 12=6804
# samples 827
** MAII scorelog2(8/270*10)=-1.75488750216347
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(27/6804*10)=-4.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLIT3 [Title/Abstract] AND ITPR2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSLIT3(168620483)-ITPR2(26943160), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSLIT3

GO:0007411

axon guidance

11748139

HgeneSLIT3

GO:0021834

chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration

11748139

HgeneSLIT3

GO:0048846

axon extension involved in axon guidance

16840550

HgeneSLIT3

GO:0050919

negative chemotaxis

11748139

TgeneITPR2

GO:0001666

response to hypoxia

19120137


check buttonFusion gene breakpoints across SLIT3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ITPR2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A1KZ-01ASLIT3chr5

168620483

-ITPR2chr12

26943160

-
ChimerDB4SARCTCGA-RN-AAAQ-01ASLIT3chr5

168620483

-ITPR2chr12

26943160

-


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Fusion Gene ORF analysis for SLIT3-ITPR2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000332966ENST00000242737SLIT3chr5

168620483

-ITPR2chr12

26943160

-
5CDS-intronENST00000332966ENST00000545902SLIT3chr5

168620483

-ITPR2chr12

26943160

-
5CDS-intronENST00000404867ENST00000242737SLIT3chr5

168620483

-ITPR2chr12

26943160

-
5CDS-intronENST00000404867ENST00000545902SLIT3chr5

168620483

-ITPR2chr12

26943160

-
5CDS-intronENST00000519560ENST00000242737SLIT3chr5

168620483

-ITPR2chr12

26943160

-
5CDS-intronENST00000519560ENST00000545902SLIT3chr5

168620483

-ITPR2chr12

26943160

-
5UTR-3CDSENST00000521130ENST00000381340SLIT3chr5

168620483

-ITPR2chr12

26943160

-
5UTR-intronENST00000521130ENST00000242737SLIT3chr5

168620483

-ITPR2chr12

26943160

-
5UTR-intronENST00000521130ENST00000545902SLIT3chr5

168620483

-ITPR2chr12

26943160

-
In-frameENST00000332966ENST00000381340SLIT3chr5

168620483

-ITPR2chr12

26943160

-
In-frameENST00000404867ENST00000381340SLIT3chr5

168620483

-ITPR2chr12

26943160

-
In-frameENST00000519560ENST00000381340SLIT3chr5

168620483

-ITPR2chr12

26943160

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000519560SLIT3chr5168620483-ENST00000381340ITPR2chr1226943160-1083583341188462811
ENST00000332966SLIT3chr5168620483-ENST00000381340ITPR2chr1226943160-104884866484992811
ENST00000404867SLIT3chr5168620483-ENST00000381340ITPR2chr1226943160-10415413084262808

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000519560ENST00000381340SLIT3chr5168620483-ITPR2chr1226943160-0.0006976620.9993024
ENST00000332966ENST00000381340SLIT3chr5168620483-ITPR2chr1226943160-0.0004437890.99955624
ENST00000404867ENST00000381340SLIT3chr5168620483-ITPR2chr1226943160-0.0003936890.9996063

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Fusion Genomic Features for SLIT3-ITPR2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SLIT3-ITPR2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:168620483/chr12:26943160)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ITPR2

Q14571

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity). {ECO:0000250|UniProtKB:Q9Z329}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-43634_611371473.0DomainNote=LRRNT
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-43634_611371524.0DomainNote=LRRNT
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436110_1311371473.0RepeatNote=LRR 3
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-43662_831371473.0RepeatNote=LRR 1
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-43686_1071371473.0RepeatNote=LRR 2
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436110_1311371524.0RepeatNote=LRR 3
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-43662_831371524.0RepeatNote=LRR 1
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-43686_1071371524.0RepeatNote=LRR 2
TgeneITPR2chr5:168620483chr12:26943160ENST0000024273706112_16630182.0DomainMIR 1
TgeneITPR2chr5:168620483chr12:26943160ENST0000024273706173_22330182.0DomainMIR 2
TgeneITPR2chr5:168620483chr12:26943160ENST0000024273706231_28730182.0DomainMIR 3
TgeneITPR2chr5:168620483chr12:26943160ENST0000024273706294_37230182.0DomainMIR 4
TgeneITPR2chr5:168620483chr12:26943160ENST0000024273706378_43430182.0DomainMIR 5
TgeneITPR2chr5:168620483chr12:26943160ENST00000381340057112_166302702.0DomainMIR 1
TgeneITPR2chr5:168620483chr12:26943160ENST00000381340057173_223302702.0DomainMIR 2
TgeneITPR2chr5:168620483chr12:26943160ENST00000381340057231_287302702.0DomainMIR 3
TgeneITPR2chr5:168620483chr12:26943160ENST00000381340057294_372302702.0DomainMIR 4
TgeneITPR2chr5:168620483chr12:26943160ENST00000381340057378_434302702.0DomainMIR 5
TgeneITPR2chr5:168620483chr12:26943160ENST0000024273706265_26930182.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR2chr5:168620483chr12:26943160ENST0000024273706507_51030182.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR2chr5:168620483chr12:26943160ENST0000024273706567_56930182.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR2chr5:168620483chr12:26943160ENST00000381340057265_269302702.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR2chr5:168620483chr12:26943160ENST00000381340057507_510302702.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR2chr5:168620483chr12:26943160ENST00000381340057567_569302702.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062249_226030182.0Topological domainExtracellular
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062282_230730182.0Topological domainCytoplasmic
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062329_235130182.0Topological domainExtracellular
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062373_239430182.0Topological domainCytoplasmic
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062416_252130182.0Topological domainExtracellular
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062543_270130182.0Topological domainCytoplasmic
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572249_2260302702.0Topological domainExtracellular
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572282_2307302702.0Topological domainCytoplasmic
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572329_2351302702.0Topological domainExtracellular
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572373_2394302702.0Topological domainCytoplasmic
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572416_2521302702.0Topological domainExtracellular
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572543_2701302702.0Topological domainCytoplasmic
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062228_224830182.0TransmembraneHelical
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062261_228130182.0TransmembraneHelical
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062308_232830182.0TransmembraneHelical
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062352_237230182.0TransmembraneHelical
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062395_241530182.0TransmembraneHelical
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737062522_254230182.0TransmembraneHelical
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572228_2248302702.0TransmembraneHelical
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572261_2281302702.0TransmembraneHelical
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572308_2328302702.0TransmembraneHelical
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572352_2372302702.0TransmembraneHelical
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572395_2415302702.0TransmembraneHelical
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400572522_2542302702.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-4361034_10721371473.0DomainEGF-like 4
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-4361074_11101371473.0DomainEGF-like 5
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-4361119_11551371473.0DomainEGF-like 6
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-4361158_13321371473.0DomainLaminin G-like
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-4361340_13651371473.0DomainEGF-like 7
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-4361368_14031371473.0DomainEGF-like 8
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-4361408_14441371473.0DomainEGF-like 9
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-4361449_15231371473.0DomainCTCK
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436215_2651371473.0DomainNote=LRRCT 1
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436271_3071371473.0DomainNote=LRRNT 2
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436437_4871371473.0DomainNote=LRRCT 2
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436496_5321371473.0DomainNote=LRRNT 3
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436663_7131371473.0DomainNote=LRRCT 3
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436716_7521371473.0DomainNote=LRRNT 4
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436857_9071371473.0DomainNote=LRRCT 4
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436918_9531371473.0DomainEGF-like 1
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436955_9941371473.0DomainEGF-like 2
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436996_10321371473.0DomainEGF-like 3
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-4361034_10721371524.0DomainEGF-like 4
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-4361074_11101371524.0DomainEGF-like 5
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-4361119_11551371524.0DomainEGF-like 6
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-4361158_13321371524.0DomainLaminin G-like
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-4361340_13651371524.0DomainEGF-like 7
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-4361368_14031371524.0DomainEGF-like 8
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-4361408_14441371524.0DomainEGF-like 9
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-4361449_15231371524.0DomainCTCK
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436215_2651371524.0DomainNote=LRRCT 1
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436271_3071371524.0DomainNote=LRRNT 2
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436437_4871371524.0DomainNote=LRRCT 2
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436496_5321371524.0DomainNote=LRRNT 3
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436663_7131371524.0DomainNote=LRRCT 3
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436716_7521371524.0DomainNote=LRRNT 4
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436857_9071371524.0DomainNote=LRRCT 4
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436918_9531371524.0DomainEGF-like 1
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436955_9941371524.0DomainEGF-like 2
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436996_10321371524.0DomainEGF-like 3
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436134_1551371473.0RepeatNote=LRR 4
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436158_1791371473.0RepeatNote=LRR 5
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436182_2031371473.0RepeatNote=LRR 6
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436308_3291371473.0RepeatNote=LRR 7
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436332_3531371473.0RepeatNote=LRR 8
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436356_3771371473.0RepeatNote=LRR 9
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436380_4011371473.0RepeatNote=LRR 10
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436404_4251371473.0RepeatNote=LRR 11
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436533_5541371473.0RepeatNote=LRR 12
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436558_5791371473.0RepeatNote=LRR 13
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436582_6031371473.0RepeatNote=LRR 14
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436606_6271371473.0RepeatNote=LRR 15
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436630_6511371473.0RepeatNote=LRR 16
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436753_7751371473.0RepeatNote=LRR 17
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436776_7971371473.0RepeatNote=LRR 18
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436800_8211371473.0RepeatNote=LRR 19
HgeneSLIT3chr5:168620483chr12:26943160ENST00000404867-436824_8451371473.0RepeatNote=LRR 20
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436134_1551371524.0RepeatNote=LRR 4
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436158_1791371524.0RepeatNote=LRR 5
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436182_2031371524.0RepeatNote=LRR 6
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436308_3291371524.0RepeatNote=LRR 7
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436332_3531371524.0RepeatNote=LRR 8
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436356_3771371524.0RepeatNote=LRR 9
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436380_4011371524.0RepeatNote=LRR 10
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436404_4251371524.0RepeatNote=LRR 11
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436533_5541371524.0RepeatNote=LRR 12
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436558_5791371524.0RepeatNote=LRR 13
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436582_6031371524.0RepeatNote=LRR 14
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436606_6271371524.0RepeatNote=LRR 15
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436630_6511371524.0RepeatNote=LRR 16
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436753_7751371524.0RepeatNote=LRR 17
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436776_7971371524.0RepeatNote=LRR 18
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436800_8211371524.0RepeatNote=LRR 19
HgeneSLIT3chr5:168620483chr12:26943160ENST00000519560-436824_8451371524.0RepeatNote=LRR 20
TgeneITPR2chr5:168620483chr12:26943160ENST00000242737061_222730182.0Topological domainCytoplasmic
TgeneITPR2chr5:168620483chr12:26943160ENST000003813400571_2227302702.0Topological domainCytoplasmic


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Fusion Gene Sequence for SLIT3-ITPR2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>83673_83673_1_SLIT3-ITPR2_SLIT3_chr5_168620483_ENST00000332966_ITPR2_chr12_26943160_ENST00000381340_length(transcript)=10488nt_BP=486nt
CGCGCGCCTCCTCGGGCTCCACGCGTCTTGCCCCGCAGAGGCAGCCTCCTCCAGGAGCGGGGCCCTGCACACCATGGCCCCCGGGTGGGC
AGGGGTCGGCGCCGCCGTGCGCGCCCGCCTGGCGCTGGCCTTGGCGCTGGCGAGCGTCCTGAGTGGGCCTCCAGCCGTCGCCTGCCCCAC
CAAGTGTACCTGCTCCGCTGCCAGCGTGGACTGCCACGGGCTGGGCCTCCGCGCGGTTCCTCGGGGCATCCCCCGCAACGCTGAGCGCCT
TGACCTGGACAGAAATAATATCACCAGGATCACCAAGATGGACTTCGCTGGGCTCAAGAACCTCCGAGTCTTGCATCTGGAAGACAACCA
GGTCAGCGTCATCGAGAGAGGCGCCTTCCAGGACCTGAAGCAGCTAGAGCGACTGCGCCTGAACAAGAATAAGCTGCAAGTCCTTCCAGA
ATTGCTTTTCCAGAGCACGCCGAAGCTCACCAGACTGTTAGTGGATGACAGATGTGTGGTGCACCCAGAGGCCGGGGACCTTGCCAACCC
TCCCAAGAAGTTCAGAGACTGCCTTTTCAAGGTGTGCCCTATGAACAGATATTCTGCCCAGAAGCAATATTGGAAAGCAAAGCAAGCCAA
ACAAGGGAACCACACCGAGGCAGCCTTGCTGAAGAAACTACAGCACGCTGCAGAACTGGAACAAAAACAAAATGAATCGGAGAATAAGAA
ACTGTTGGGAGAAATTGTAAAATACAGTAATGTTATACAACTACTGCATATAAAAAGCAACAAATATCTTACTGTCAACAAGAGATTACC
TGCTTTACTGGAGAAGAATGCCATGCGTGTGTCCTTGGATGCTGCAGGAAATGAAGGGTCTTGGTTTTATATTCATCCGTTCTGGAAACT
GAGAAGCGAGGGTGACAATATTGTTGTAGGAGATAAAGTTGTTTTGATGCCTGTGAATGCAGGGCAGCCACTACATGCCAGCAACATAGA
GCTTCTTGATAACCCAGGGTGTAAAGAGGTGAATGCTGTCAATTGCAACACCAGCTGGAAAATCACTTTATTCATGAAATATAGTTCCTA
TCGAGAGGATGTATTAAAAGGAGGGGACGTTGTTAGATTATTTCATGCGGAACAAGAGAAGTTTTTGACTTGTGATGAATATGAGAAAAA
ACAGCACATTTTCCTTCGTACGACCTTGCGCCAATCAGCTACTTCTGCTACTAGTTCTAAAGCACTCTGGGAAATAGAGGTGGTTCATCA
TGACCCATGCCGTGGGGGTGCAGGACAGTGGAACAGCTTGTTCAGATTTAAGCATCTTGCAACTGGAAACTATTTAGCTGCAGAGCTTAA
TCCTGATTATCGAGATGCCCAAAATGAAGGAAAAAATGTGAGAGATGGAGTCCCTCCAACTTCAAAGAAAAAACGCCAGGCAGGGGAGAA
GATCATGTATACTTTGGTTTCAGTCCCGCATGGCAATGACATTGCATCCCTTTTTGAACTAGATGCCACAACTCTTCAGAGAGCTGACTG
CCTGGTTCCAAGGAACTCATATGTTCGGTTAAGGCATTTATGCACCAACACATGGGTAACCAGTACTAGTATCCCCATAGACACAGATGA
AGAGAGGCCTGTTATGTTAAAGATTGGAACCTGCCAAACCAAAGAAGATAAAGAAGCGTTCGCAATCGTGTCTGTTCCACTGTCTGAAGT
TCGAGACTTAGACTTTGCCAATGATGCCAATAAAGTACTAGCGACCACAGTTAAAAAGCTAGAAAACGGCACAATAACTCAGAATGAAAG
GAGGTTTGTAACCAAATTATTGGAAGATCTCATATTCTTTGTTGCTGATGTGCCTAATAATGGACAAGAAGTTCTGGATGTGGTTATCAC
TAAGCCAAACCGAGAGCGTCAAAAATTGATGAGGGAACAAAACATACTGGCACAGGTATTTGGAATTCTTAAAGCACCCTTTAAAGAGAA
AGCAGGAGAAGGCTCGATGCTGAGACTTGAAGATCTGGGGGATCAAAGATATGCACCCTACAAGTACATGCTGCGGCTCTGTTACCGCGT
CCTGAGACACTCGCAGCAGGATTACCGGAAAAATCAGGAATATATTGCTAAGAATTTCTGTGTCATGCAGTCCCAGATTGGCTATGATAT
TTTGGCAGAAGATACTATCACAGCTTTGTTGCACAACAACAGAAAACTACTAGAGAAACATATCACAGCAAAAGAAATAGAAACATTTGT
CAGTTTACTCAGGAGAAATCGGGAGCCAAGGTTTTTGGATTATTTGTCAGATCTGTGTGTGTCTAATACCACTGCTATCCCTGTAACTCA
AGAACTCATCTGTAAATTTATGTTGAGTCCAGGCAATGCAGACATTCTCATTCAAACTAAGGTGGTCTCAATGCAAGCAGACAACCCCAT
GGAGAGCTCCATCCTTTCAGATGACATTGATGATGAAGAAGTTTGGCTCTATTGGATTGACAGCAACAAGGAACCTCATGGCAAAGCTAT
CAGGCACCTTGCTCAAGAGGCAAAAGAAGGCACCAAAGCTGACTTAGAAGTTCTTACCTATTACAGGTACCAGCTAAACCTCTTTGCAAG
GATGTGCTTGGATCGCCAGTATCTGGCCATAAACCAGATTTCTACACAGCTGTCTGTAGACCTGATCCTGCGGTGTGTGTCGGATGAGAG
CCTGCCGTTCGACCTCCGAGCGTCCTTCTGTCGCCTCATGCTCCACATGCACGTTGACCGGGATCCCCAGGAGTCCGTGGTGCCTGTTCG
CTATGCCAGGCTCTGGACAGAAATCCCCACAAAGATCACAATTCATGAATATGATTCTATAACAGACTCTTCCAGAAATGATATGAAGAG
GAAATTTGCCCTGACAATGGAATTTGTTGAAGAATATTTGAAAGAAGTTGTAAACCAGCCCTTTCCTTTTGGGGATAAAGAAAAAAATAA
ACTGACATTTGAGGTGGTCCACTTGGCTCGGAATCTTATATACTTTGGATTTTATAGTTTCAGTGAGTTATTAAGGCTAACAAGAACACT
TCTGGCTATTTTAGACATTGTACAGGCCCCCATGTCATCATACTTTGAAAGATTAAGCAAATTTCAAGATGGAGGAAACAATGTGATGAG
AACCATTCATGGGGTGGGAGAGATGATGACCCAGATGGTACTCAGTAGAGGCTCCATCTTCCCCATGAGCGTGCCGGATGTGCCACCCAG
CATCCACCCGAGCAAGCAAGGGAGCCCCACCGAGCACGAGGATGTGACTGTGATGGACACCAAGCTGAAGATCATTGAGATTTTGCAGTT
TATCCTGAGTGTCAGACTGGATTATAGGATCTCATATATGCTGTCAATATATAAGAAGGAGTTTGGAGAGGACAATGACAATGCGGAGAC
ATCTGCCAGTGGATCTCCAGACACTTTACTACCATCAGCTATTGTTCCTGATATAGATGAAATTGCAGCTCAGGCAGAAACTATGTTTGC
GGGAAGAAAAGAAAAAAATCCAGTTCAACTTGACGATGAAGGAGGCAGGACGTTTTTACGGGTCCTCATTCATCTGATCATGCACGACTA
CCCGCCTTTGCTGTCTGGAGCCCTGCAGCTGTTGTTTAAGCACTTCAGCCAGAGGGCAGAGGTTTTACAGGCATTTAAGCAGGTGCAATT
ACTGGTGTCTAATCAAGACGTAGATAACTACAAGCAAATCAAGGCAGATCTAGACCAGCTTCGACTGACAGTAGAAAAGTCTGAGCTATG
GGTGGAGAAGAGCAGCAACTATGAGAATGGAGAAATAGGGGAAAGTCAAGTGAAAGGTGGTGAAGAGCCAATTGAGGAATCAAACATTTT
AAGTCCAGTGCAGGATGGAACAAAGAAACCTCAGATTGACAGCAACAAGAGCAATAACTACCGGATTGTAAAGGAGATTTTGATCAGGCT
AAGTAAACTCTGTGTGCAGAATAAAAAGTGTCGGAATCAACATCAACGATTACTGAAAAATATGGGGGCGCATTCGGTGGTGTTGGATCT
TCTGCAGATACCCTATGAAAAGAATGATGAAAAGATGAATGAAGTAATGAATCTAGCCCATACATTTCTGCAGAATTTCTGTCGAGGAAA
TCCACAGAATCAAGTTCTTCTTCATAAACATCTGAATTTGTTTTTAACTCCAGGTCTCCTTGAAGCAGAAACCATGCGGCACATCTTCAT
GAACAATTACCATCTGTGCAACGAAATTAGCGAGAGAGTTGTACAACACTTTGTGCACTGCATTGAGACACATGGCCGCCACGTGGAGTA
CCTGAGGTTTTTGCAAACAATTGTAAAAGCAGATGGTAAATATGTGAAGAAATGCCAGGATATGGTAATGACAGAGTTGATAAATGGGGG
TGAAGACGTGCTGATATTTTACAATGATAGAGCATCATTTCCAATCCTTCTCCATATGATGTGTTCAGAGAGAGACCGAGGGGATGAGAG
TGGCCCCTTAGCCTACCACATCACCCTGGTGGAGTTGCTGGCAGCATGCACAGAGGGGAAAAATGTCTACACTGAAATCAAGTGTAATTC
CCTTCTCCCGCTGGACGACATAGTGAGGGTGGTGACCCATGACGACTGCATCCCTGAGGTTAAAATTGCTTATGTGAACTTTGTTAATCA
CTGTTATGTTGACACTGAAGTGGAAATGAAAGAAATCTATACAAGTAACCACATTTGGAAATTATTTGAGAACTTCTTGGTGGATATGGC
AAGGGTTTGCAACACAACTACAGACAGGAAACATGCAGACATCTTTTTGGAAAAGTGTGTTACTGAGTCAATAATGAATATTGTGAGCGG
CTTCTTTAATTCTCCCTTTTCAGACAATAGTACCAGCCTCCAGACACATCAGCCAGTTTTTATTCAGCTACTGCAATCTGCCTTCAGAAT
TTACAATTGCACCTGGCCAAACCCAGCGCAGAAAGCCTCAGTGGAATCCTGTATCAGAACTTTGGCTGAAGTGGCAAAAAATCGTGGAAT
TGCCATTCCAGTGGATTTGGACAGCCAAGTTAATACTCTTTTCATGAAGAGCCATTCAAATATGGTGCAGAGAGCAGCAATGGGTTGGAG
ACTATCAGCTCGCTCTGGGCCACGCTTTAAGGAAGCTCTTGGAGGGCCTGCTTGGGATTACAGAAATATTATTGAAAAGTTACAGGATGT
AGTGGCCTCCTTGGAGCACCAGTTCAGCCCAATGATGCAGGCTGAATTCTCAGTGTTGGTTGATGTATTGTACAGTCCAGAACTGCTGTT
CCCTGAGGGAAGCGATGCAAGAATAAGATGTGGCGCTTTCATGTCGAAGTTGATTAATCATACAAAGAAACTAATGGAGAAAGAAGAAAA
ACTGTGCATTAAAATTCTTCAGACATTACGAGAAATGTTAGAGAAGAAAGACAGCTTTGTGGAAGAGGGTAACACATTAAGAAAGATACT
TCTGAATCGATACTTTAAAGGTGATTATAGTATTGGTGTGAATGGACACCTATCAGGAGCCTACTCCAAAACTGCACAGGTGGGAGGAAG
CTTTTCTGGACAAGATTCAGATAAGATGGGGATATCAATGTCAGACATTCAGTGTCTGCTGGATAAAGAAGGTGCATCAGAACTTGTCAT
CGATGTTATAGTGAACACCAAAAATGACAGAATTTTTTCAGAAGGCATTTTCCTCGGCATTGCCTTGCTTGAAGGAGGAAATACACAAAC
ACAGTATTCTTTCTACCAGCAGTTGCATGAACAAAAAAAGTCAGAAAAATTCTTTAAAGTTCTCTATGATCGAATGAAGGCTGCTCAGAA
AGAAATAAGATCAACAGTGACAGTTAATACCATAGATTTAGGTAACAAAAAAAGGGACGATGACAATGAATTGATGACATCTGGTCCACG
AATGAGAGTAAGAGATTCAACACTACATTTAAAAGAGGGAATGAAAGGGCAATTAACAGAAGCTTCTTCAGCAACATCCAAAGCATATTG
TGTATACAGAAGAGAAATGGATCCAGAAATAGACATTATGTGCACAGGACCAGAAGCGGGAAACACTGAGGAAAAATCCGCAGAGGAAGT
AACAATGAGTCCCGCAATTGCCATCATGCAGCCAATACTGAGATTTCTTCAGTTACTGTGTGAGAATCACAACCGGGAATTGCAGAACTT
CTTGAGGAATCAAAACAACAAAACAAATTACAACCTAGTCTGTGAGACCCTTCAGTTTCTGGACTGCATTTGTGGAAGTACAACCGGTGG
CCTGGGCCTGTTGGGTCTCTACATCAATGAGAAGAATGTAGCGCTGGTCAACCAGAACCTGGAGAGCTTGACTGAGTATTGCCAGGGCCC
TTGCCATGAAAATCAGACCTGTATCGCTACACATGAGTCTAATGGGATTGATATCATCATTGCTTTGATTCTGAATGACATAAACCCTCT
TGGTAAATACCGAATGGACCTGGTGCTCCAGCTAAAGAACAATGCATCTAAACTTTTGCTGGCCATTATGGAAAGCAGACATGACAGTGA
GAATGCAGAAAGAATTCTTTTTAACATGAGACCCAGAGAACTGGTGGATGTGATGAAGAATGCCTATAACCAAGGATTGGAATGTGACCA
TGGGGATGATGAGGGTGGAGATGATGGTGTTTCTCCAAAAGATGTTGGACACAATATCTATATTCTGGCCCATCAGTTGGCCCGCCACAA
TAAACTGTTGCAGCAGATGCTCAAACCAGGATCGGATCCAGATGAAGGAGATGAAGCCTTAAAGTATTATGCCAACCACACTGCACAGAT
TGAGATTGTCCGGCATGATAGGACCATGGAACAAATAGTTTTTCCTGTCCCCAATATATGTGAATACCTCACTCGAGAATCCAAGTGCCG
TGTGTTCAATACAACTGAAAGGGATGAACAAGGAAGTAAAGTGAATGACTTTTTCCAGCAAACAGAAGATCTCTACAATGAAATGAAGTG
GCAGAAGAAAATCAGGAATAACCCTGCACTGTTCTGGTTCTCGAGGCACATCTCTCTCTGGGGGAGCATTTCCTTCAACCTGGCTGTGTT
CATCAATTTAGCTGTTGCTCTCTTCTACCCATTTGGGGATGATGGAGATGAAGGTACACTTTCTCCATTGTTCTCGGTTCTTCTTTGGAT
AGCAGTTGCGATCTGCACATCTATGCTGTTTTTCTTCTCCAAGCCTGTGGGTATTCGGCCGTTTCTTGTATCAATAATGCTCAGATCAAT
ATATACAATAGGTCTTGGGCCTACATTAATACTTCTTGGTGCAGCTAATCTTTGTAATAAAATTGTTTTTCTGGTGAGTTTTGTTGGAAA
TCGTGGCACGTTCACCCGTGGGTACCGAGCAGTCATCCTGGATATGGCCTTTCTCTATCACGTGGCGTATGTCCTGGTTTGCATGCTGGG
CCTTTTTGTCCATGAATTCTTCTATAGCTTCCTGCTTTTTGATTTGGTGTACAGGGAAGAGACTTTGCTGAATGTCATAAAAAGTGTCAC
ACGAAATGGCCGCTCTATTATTCTAACTGCAGTCCTGGCTCTCATCCTCGTCTACCTGTTTTCCATTATTGGGTTCCTTTTTTTGAAGGA
TGACTTCACTATGGAAGTTGATAGGCTGAAAAACCGAACTCCTGTTACAGGCAGTCATCAAGTGCCTACTATGACTTTAACTACCATGAT
GGAAGCATGTGCCAAGGAGAACTGTTCACCCACAATTCCAGCTTCAAATACAGCTGATGAAGAGTATGAAGATGGAATTGAAAGGACGTG
TGACACTCTCCTTATGTGCATTGTCACCGTGCTGAACCAGGGCCTCAGGAATGGCGGTGGTGTGGGGGATGTGCTAAGAAGGCCATCGAA
AGATGAGCCCTTGTTTGCTGCCCGAGTGGTTTATGACCTTCTTTTTTATTTCATTGTTATCATTATTGTTCTGAACTTGATTTTTGGTGT
TATCATCGATACTTTTGCTGATCTCAGAAGCGAAAAACAGAAAAAAGAAGAAATTCTAAAGACAACTTGTTTCATCTGTGGACTTGAGAG
AGACAAGTTTGATAATAAAACGGTTTCATTTGAGGAGCACATTAAGTCAGAACACAATATGTGGCATTATTTGTACTTCATAGTCCTGGT
GAAAGTTAAAGACCCAACAGAATACACTGGACCTGAAAGTTATGTGGCTCAAATGATTGTGGAGAAGAATTTGGATTGGTTTCCTCGGAT
GCGAGCCATGTCCCTCGTTAGCAATGAAGGCGACAGTGAGCAAAATGAAATTCGGAGCCTTCAGGAGAAGTTGGAATCGACCATGAGTCT
GGTCAAACAGCTGTCGGGTCAGCTGGCGGAGCTCAAGGAGCAGATGACAGAACAAAGGAAGAATAAGCAGAGACTGGGCTTCCTCGGATC
AAACACACCCCATGTGAATCATCACATGCCACCACACTGATACCATGGGGGGAAGCCGTGACTAGCCTTTCATCAGTGTCCTGCCTGATC
ACTGAATAAAGAACTGAGATGGAGGGGAGTGAACAGTGCCTATTGTTGAAAAGTTAAAAACAACCAAGTGCCAAGATGTTGAGTGGGTTA
GCTCCGAGAACAATTTATAACTGTGTTTTCATGGTTGCGAAGACCTAACCTCAAATGCATCTGCTAGAAAGCGTACATCACACATTCGCA
ATGCATCAGGAAGAAAAGGCTTGCCCAAAAGGCTGGAGAGGGCAGGGAGCGGCAGGATGGAAGGAGACACGGGGCAGGGAGAACTCTCTT
CTGCTAAATCGATAGGAGTCAGTTTTGTCTTAAATGCTGACTACAGCCACTGACATGGTTGGCTGGAATTTCTTTCTTTTAATTGTGGCA
TATAGGTTTGTGACACAAGAAGTCATACTTTGGTGGCTAAGTTTTACTAAGGAAAATAACTGAAAAGATTAAAAGTGAGAGCTGAAAAGA
GAAATGATAATGCTTCCAAACTGTAGCTGTCACAGGGCAATTTCTTTATTTATAACATGAAGCACAATGGATTTACAGCTCTAGGAACTT
AGTACTTTGGAGCTTTTGCCTCTCACACTGACAACATAACAGGATGTGATTGCCTTCTCTGGGATTCAGACAGGCTCTGTCAATGTGGAG
CACAAAAGGAGATTTTCATATAACTTGTTAAAAACATGTTCTAAGTCATGTATAGGCTAAGATTTTAAGAAGATCTGGGGGAATAAAAAG
CCAACAGTAAGCCCCAGGAAAGGGTTTTTTGAGACCATATGTATGCTATTAAAATATATTGAGATTAATACATGAAAATGCTTAAAAGTG
ATAGGAATTATTGAGAAACTTATGATGGTGGCATTGCCTTTTATAAACATGGAGTGAAAGCCATTTGACTCAACGTTTGCTGTGCTTAAA
GAATTGCTTCAGGACCCGAGCGTTTTTATGTATGCTGTTCCTGCAGTTAGGAAAAAAAAATCCAAGAAATGTATTGAATACTCAAGAAAA
TGCCACATTTCAATTACATATTTAAAACTGTATCTGTAAGGGCTTTTCAAAATGTAGCAAGATAAAAATCTCTTATTCAAATTGTTTTTG
TATTAAATCATGCACTCAGAATTTGTCGAGGGAGAGAATAACCTGGTGTGTTCAGGTTATTCTTAGAGACTACACATTTGGAATAGCAGA
GCAAAATATGGATAATGAAAGTGTTGGGAAAAAAGTGATGTGACAGGGAGTGAAGACACTTGATACCAGACTCTGGGAGATACTCTGCAA
GTTGACCTGGCCTCTCCCCCACAGGAACAAAACACTGCCTCCAGAGTCTTTAAATTCTCAGTTATCAACGCCAAGGTTTAAGGTCTAGAT
AGGGTTTGCTATAGGGTTTGCTCTGACAATTTTTAAAGCTTTTGGATTGTTCTAACATAGCTTAAGCTATTGGTTCCTAAAAATCCCAAA
TCAAGATCTATGTAGAATATAAAGGAAGCCTGAACCAATCCTTCCACATACTGTTAAGATGTAGACTTGGAACAAAGCTGTTGGGACCCA
GAGCAATGAATTTTTGAACTGAAGCTACTGGTACTCCCCAGCACCACCTCATACTAAGAATTCCTCACTCTGACATGACAGTATTTTTTC
TGACCAGGAGCTGAAAGACCCTGACATTCATGATCCAAAGATATAAGAAATTTTGATATGTCTGCATGCAGCACAGAACTTTGAACCTAG
GAGGCAGTCAATAAATACATGAGAAATTCAGCTGTCATTCAGTTACTCTTAATTCTTTATAAAACTTTAAATGATACCACATATTTGTTT
GTTTAAAATGGCTTTCCCAAAATCAAAGTAGACTAAAGCAGCCATCTTTAAAATCCAGGATCATCAATGCTATTAACAGTATCAGGTAAA

>83673_83673_1_SLIT3-ITPR2_SLIT3_chr5_168620483_ENST00000332966_ITPR2_chr12_26943160_ENST00000381340_length(amino acids)=2811AA_BP=141
MHTMAPGWAGVGAAVRARLALALALASVLSGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNL
RVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLLVDDRCVVHPEAGDLANPPKKFRDCLFKVCPMNRYSAQK
QYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENKKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSW
FYIHPFWKLRSEGDNIVVGDKVVLMPVNAGQPLHASNIELLDNPGCKEVNAVNCNTSWKITLFMKYSSYREDVLKGGDVVRLFHAEQEKF
LTCDEYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVRDGVPPTS
KKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTDEERPVMLKIGTCQTKEDKEAFA
IVSVPLSEVRDLDFANDANKVLATTVKKLENGTITQNERRFVTKLLEDLIFFVADVPNNGQEVLDVVITKPNRERQKLMREQNILAQVFG
ILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYMLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHI
TAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPGNADILIQTKVVSMQADNPMESSILSDDIDDEEVWLYWIDS
NKEPHGKAIRHLAQEAKEGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRD
PQESVVPVRYARLWTEIPTKITIHEYDSITDSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFS
ELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPMSVPDVPPSIHPSKQGSPTEHEDVTVMDTK
LKIIEILQFILSVRLDYRISYMLSIYKKEFGEDNDNAETSASGSPDTLLPSAIVPDIDEIAAQAETMFAGRKEKNPVQLDDEGGRTFLRV
LIHLIMHDYPPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSSNYENGEIGESQVKGGE
EPIEESNILSPVQDGTKKPQIDSNKSNNYRIVKEILIRLSKLCVQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEKNDEKMNEVMNLAHT
FLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDM
VMTELINGGEDVLIFYNDRASFPILLHMMCSERDRGDESGPLAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVK
IAYVNFVNHCYVDTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRKHADIFLEKCVTESIMNIVSGFFNSPFSDNSTSLQTHQPVFI
QLLQSAFRIYNCTWPNPAQKASVESCIRTLAEVAKNRGIAIPVDLDSQVNTLFMKSHSNMVQRAAMGWRLSARSGPRFKEALGGPAWDYR
NIIEKLQDVVASLEHQFSPMMQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINHTKKLMEKEEKLCIKILQTLREMLEKKDSFVE
EGNTLRKILLNRYFKGDYSIGVNGHLSGAYSKTAQVGGSFSGQDSDKMGISMSDIQCLLDKEGASELVIDVIVNTKNDRIFSEGIFLGIA
LLEGGNTQTQYSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGNKKRDDDNELMTSGPRMRVRDSTLHLKEGMKGQLTEA
SSATSKAYCVYRREMDPEIDIMCTGPEAGNTEEKSAEEVTMSPAIAIMQPILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLD
CICGSTTGGLGLLGLYINEKNVALVNQNLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLGKYRMDLVLQLKNNASKLLLA
IMESRHDSENAERILFNMRPRELVDVMKNAYNQGLECDHGDDEGGDDGVSPKDVGHNIYILAHQLARHNKLLQQMLKPGSDPDEGDEALK
YYANHTAQIEIVRHDRTMEQIVFPVPNICEYLTRESKCRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWG
SISFNLAVFINLAVALFYPFGDDGDEGTLSPLFSVLLWIAVAICTSMLFFFSKPVGIRPFLVSIMLRSIYTIGLGPTLILLGAANLCNKI
VFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFS
IIGFLFLKDDFTMEVDRLKNRTPVTGSHQVPTMTLTTMMEACAKENCSPTIPASNTADEEYEDGIERTCDTLLMCIVTVLNQGLRNGGGV
GDVLRRPSKDEPLFAARVVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMW
HYLYFIVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSNEGDSEQNEIRSLQEKLESTMSLVKQLSGQLAELKEQMTEQRKN

--------------------------------------------------------------
>83673_83673_2_SLIT3-ITPR2_SLIT3_chr5_168620483_ENST00000404867_ITPR2_chr12_26943160_ENST00000381340_length(transcript)=10415nt_BP=413nt
ATGGCCCCCGGGTGGGCAGGGGTCGGCGCCGCCGTGCGCGCCCGCCTGGCGCTGGCCTTGGCGCTGGCGAGCGTCCTGAGTGGGCCTCCA
GCCGTCGCCTGCCCCACCAAGTGTACCTGCTCCGCTGCCAGCGTGGACTGCCACGGGCTGGGCCTCCGCGCGGTTCCTCGGGGCATCCCC
CGCAACGCTGAGCGCCTTGACCTGGACAGAAATAATATCACCAGGATCACCAAGATGGACTTCGCTGGGCTCAAGAACCTCCGAGTCTTG
CATCTGGAAGACAACCAGGTCAGCGTCATCGAGAGAGGCGCCTTCCAGGACCTGAAGCAGCTAGAGCGACTGCGCCTGAACAAGAATAAG
CTGCAAGTCCTTCCAGAATTGCTTTTCCAGAGCACGCCGAAGCTCACCAGACTGTTAGTGGATGACAGATGTGTGGTGCACCCAGAGGCC
GGGGACCTTGCCAACCCTCCCAAGAAGTTCAGAGACTGCCTTTTCAAGGTGTGCCCTATGAACAGATATTCTGCCCAGAAGCAATATTGG
AAAGCAAAGCAAGCCAAACAAGGGAACCACACCGAGGCAGCCTTGCTGAAGAAACTACAGCACGCTGCAGAACTGGAACAAAAACAAAAT
GAATCGGAGAATAAGAAACTGTTGGGAGAAATTGTAAAATACAGTAATGTTATACAACTACTGCATATAAAAAGCAACAAATATCTTACT
GTCAACAAGAGATTACCTGCTTTACTGGAGAAGAATGCCATGCGTGTGTCCTTGGATGCTGCAGGAAATGAAGGGTCTTGGTTTTATATT
CATCCGTTCTGGAAACTGAGAAGCGAGGGTGACAATATTGTTGTAGGAGATAAAGTTGTTTTGATGCCTGTGAATGCAGGGCAGCCACTA
CATGCCAGCAACATAGAGCTTCTTGATAACCCAGGGTGTAAAGAGGTGAATGCTGTCAATTGCAACACCAGCTGGAAAATCACTTTATTC
ATGAAATATAGTTCCTATCGAGAGGATGTATTAAAAGGAGGGGACGTTGTTAGATTATTTCATGCGGAACAAGAGAAGTTTTTGACTTGT
GATGAATATGAGAAAAAACAGCACATTTTCCTTCGTACGACCTTGCGCCAATCAGCTACTTCTGCTACTAGTTCTAAAGCACTCTGGGAA
ATAGAGGTGGTTCATCATGACCCATGCCGTGGGGGTGCAGGACAGTGGAACAGCTTGTTCAGATTTAAGCATCTTGCAACTGGAAACTAT
TTAGCTGCAGAGCTTAATCCTGATTATCGAGATGCCCAAAATGAAGGAAAAAATGTGAGAGATGGAGTCCCTCCAACTTCAAAGAAAAAA
CGCCAGGCAGGGGAGAAGATCATGTATACTTTGGTTTCAGTCCCGCATGGCAATGACATTGCATCCCTTTTTGAACTAGATGCCACAACT
CTTCAGAGAGCTGACTGCCTGGTTCCAAGGAACTCATATGTTCGGTTAAGGCATTTATGCACCAACACATGGGTAACCAGTACTAGTATC
CCCATAGACACAGATGAAGAGAGGCCTGTTATGTTAAAGATTGGAACCTGCCAAACCAAAGAAGATAAAGAAGCGTTCGCAATCGTGTCT
GTTCCACTGTCTGAAGTTCGAGACTTAGACTTTGCCAATGATGCCAATAAAGTACTAGCGACCACAGTTAAAAAGCTAGAAAACGGCACA
ATAACTCAGAATGAAAGGAGGTTTGTAACCAAATTATTGGAAGATCTCATATTCTTTGTTGCTGATGTGCCTAATAATGGACAAGAAGTT
CTGGATGTGGTTATCACTAAGCCAAACCGAGAGCGTCAAAAATTGATGAGGGAACAAAACATACTGGCACAGGTATTTGGAATTCTTAAA
GCACCCTTTAAAGAGAAAGCAGGAGAAGGCTCGATGCTGAGACTTGAAGATCTGGGGGATCAAAGATATGCACCCTACAAGTACATGCTG
CGGCTCTGTTACCGCGTCCTGAGACACTCGCAGCAGGATTACCGGAAAAATCAGGAATATATTGCTAAGAATTTCTGTGTCATGCAGTCC
CAGATTGGCTATGATATTTTGGCAGAAGATACTATCACAGCTTTGTTGCACAACAACAGAAAACTACTAGAGAAACATATCACAGCAAAA
GAAATAGAAACATTTGTCAGTTTACTCAGGAGAAATCGGGAGCCAAGGTTTTTGGATTATTTGTCAGATCTGTGTGTGTCTAATACCACT
GCTATCCCTGTAACTCAAGAACTCATCTGTAAATTTATGTTGAGTCCAGGCAATGCAGACATTCTCATTCAAACTAAGGTGGTCTCAATG
CAAGCAGACAACCCCATGGAGAGCTCCATCCTTTCAGATGACATTGATGATGAAGAAGTTTGGCTCTATTGGATTGACAGCAACAAGGAA
CCTCATGGCAAAGCTATCAGGCACCTTGCTCAAGAGGCAAAAGAAGGCACCAAAGCTGACTTAGAAGTTCTTACCTATTACAGGTACCAG
CTAAACCTCTTTGCAAGGATGTGCTTGGATCGCCAGTATCTGGCCATAAACCAGATTTCTACACAGCTGTCTGTAGACCTGATCCTGCGG
TGTGTGTCGGATGAGAGCCTGCCGTTCGACCTCCGAGCGTCCTTCTGTCGCCTCATGCTCCACATGCACGTTGACCGGGATCCCCAGGAG
TCCGTGGTGCCTGTTCGCTATGCCAGGCTCTGGACAGAAATCCCCACAAAGATCACAATTCATGAATATGATTCTATAACAGACTCTTCC
AGAAATGATATGAAGAGGAAATTTGCCCTGACAATGGAATTTGTTGAAGAATATTTGAAAGAAGTTGTAAACCAGCCCTTTCCTTTTGGG
GATAAAGAAAAAAATAAACTGACATTTGAGGTGGTCCACTTGGCTCGGAATCTTATATACTTTGGATTTTATAGTTTCAGTGAGTTATTA
AGGCTAACAAGAACACTTCTGGCTATTTTAGACATTGTACAGGCCCCCATGTCATCATACTTTGAAAGATTAAGCAAATTTCAAGATGGA
GGAAACAATGTGATGAGAACCATTCATGGGGTGGGAGAGATGATGACCCAGATGGTACTCAGTAGAGGCTCCATCTTCCCCATGAGCGTG
CCGGATGTGCCACCCAGCATCCACCCGAGCAAGCAAGGGAGCCCCACCGAGCACGAGGATGTGACTGTGATGGACACCAAGCTGAAGATC
ATTGAGATTTTGCAGTTTATCCTGAGTGTCAGACTGGATTATAGGATCTCATATATGCTGTCAATATATAAGAAGGAGTTTGGAGAGGAC
AATGACAATGCGGAGACATCTGCCAGTGGATCTCCAGACACTTTACTACCATCAGCTATTGTTCCTGATATAGATGAAATTGCAGCTCAG
GCAGAAACTATGTTTGCGGGAAGAAAAGAAAAAAATCCAGTTCAACTTGACGATGAAGGAGGCAGGACGTTTTTACGGGTCCTCATTCAT
CTGATCATGCACGACTACCCGCCTTTGCTGTCTGGAGCCCTGCAGCTGTTGTTTAAGCACTTCAGCCAGAGGGCAGAGGTTTTACAGGCA
TTTAAGCAGGTGCAATTACTGGTGTCTAATCAAGACGTAGATAACTACAAGCAAATCAAGGCAGATCTAGACCAGCTTCGACTGACAGTA
GAAAAGTCTGAGCTATGGGTGGAGAAGAGCAGCAACTATGAGAATGGAGAAATAGGGGAAAGTCAAGTGAAAGGTGGTGAAGAGCCAATT
GAGGAATCAAACATTTTAAGTCCAGTGCAGGATGGAACAAAGAAACCTCAGATTGACAGCAACAAGAGCAATAACTACCGGATTGTAAAG
GAGATTTTGATCAGGCTAAGTAAACTCTGTGTGCAGAATAAAAAGTGTCGGAATCAACATCAACGATTACTGAAAAATATGGGGGCGCAT
TCGGTGGTGTTGGATCTTCTGCAGATACCCTATGAAAAGAATGATGAAAAGATGAATGAAGTAATGAATCTAGCCCATACATTTCTGCAG
AATTTCTGTCGAGGAAATCCACAGAATCAAGTTCTTCTTCATAAACATCTGAATTTGTTTTTAACTCCAGGTCTCCTTGAAGCAGAAACC
ATGCGGCACATCTTCATGAACAATTACCATCTGTGCAACGAAATTAGCGAGAGAGTTGTACAACACTTTGTGCACTGCATTGAGACACAT
GGCCGCCACGTGGAGTACCTGAGGTTTTTGCAAACAATTGTAAAAGCAGATGGTAAATATGTGAAGAAATGCCAGGATATGGTAATGACA
GAGTTGATAAATGGGGGTGAAGACGTGCTGATATTTTACAATGATAGAGCATCATTTCCAATCCTTCTCCATATGATGTGTTCAGAGAGA
GACCGAGGGGATGAGAGTGGCCCCTTAGCCTACCACATCACCCTGGTGGAGTTGCTGGCAGCATGCACAGAGGGGAAAAATGTCTACACT
GAAATCAAGTGTAATTCCCTTCTCCCGCTGGACGACATAGTGAGGGTGGTGACCCATGACGACTGCATCCCTGAGGTTAAAATTGCTTAT
GTGAACTTTGTTAATCACTGTTATGTTGACACTGAAGTGGAAATGAAAGAAATCTATACAAGTAACCACATTTGGAAATTATTTGAGAAC
TTCTTGGTGGATATGGCAAGGGTTTGCAACACAACTACAGACAGGAAACATGCAGACATCTTTTTGGAAAAGTGTGTTACTGAGTCAATA
ATGAATATTGTGAGCGGCTTCTTTAATTCTCCCTTTTCAGACAATAGTACCAGCCTCCAGACACATCAGCCAGTTTTTATTCAGCTACTG
CAATCTGCCTTCAGAATTTACAATTGCACCTGGCCAAACCCAGCGCAGAAAGCCTCAGTGGAATCCTGTATCAGAACTTTGGCTGAAGTG
GCAAAAAATCGTGGAATTGCCATTCCAGTGGATTTGGACAGCCAAGTTAATACTCTTTTCATGAAGAGCCATTCAAATATGGTGCAGAGA
GCAGCAATGGGTTGGAGACTATCAGCTCGCTCTGGGCCACGCTTTAAGGAAGCTCTTGGAGGGCCTGCTTGGGATTACAGAAATATTATT
GAAAAGTTACAGGATGTAGTGGCCTCCTTGGAGCACCAGTTCAGCCCAATGATGCAGGCTGAATTCTCAGTGTTGGTTGATGTATTGTAC
AGTCCAGAACTGCTGTTCCCTGAGGGAAGCGATGCAAGAATAAGATGTGGCGCTTTCATGTCGAAGTTGATTAATCATACAAAGAAACTA
ATGGAGAAAGAAGAAAAACTGTGCATTAAAATTCTTCAGACATTACGAGAAATGTTAGAGAAGAAAGACAGCTTTGTGGAAGAGGGTAAC
ACATTAAGAAAGATACTTCTGAATCGATACTTTAAAGGTGATTATAGTATTGGTGTGAATGGACACCTATCAGGAGCCTACTCCAAAACT
GCACAGGTGGGAGGAAGCTTTTCTGGACAAGATTCAGATAAGATGGGGATATCAATGTCAGACATTCAGTGTCTGCTGGATAAAGAAGGT
GCATCAGAACTTGTCATCGATGTTATAGTGAACACCAAAAATGACAGAATTTTTTCAGAAGGCATTTTCCTCGGCATTGCCTTGCTTGAA
GGAGGAAATACACAAACACAGTATTCTTTCTACCAGCAGTTGCATGAACAAAAAAAGTCAGAAAAATTCTTTAAAGTTCTCTATGATCGA
ATGAAGGCTGCTCAGAAAGAAATAAGATCAACAGTGACAGTTAATACCATAGATTTAGGTAACAAAAAAAGGGACGATGACAATGAATTG
ATGACATCTGGTCCACGAATGAGAGTAAGAGATTCAACACTACATTTAAAAGAGGGAATGAAAGGGCAATTAACAGAAGCTTCTTCAGCA
ACATCCAAAGCATATTGTGTATACAGAAGAGAAATGGATCCAGAAATAGACATTATGTGCACAGGACCAGAAGCGGGAAACACTGAGGAA
AAATCCGCAGAGGAAGTAACAATGAGTCCCGCAATTGCCATCATGCAGCCAATACTGAGATTTCTTCAGTTACTGTGTGAGAATCACAAC
CGGGAATTGCAGAACTTCTTGAGGAATCAAAACAACAAAACAAATTACAACCTAGTCTGTGAGACCCTTCAGTTTCTGGACTGCATTTGT
GGAAGTACAACCGGTGGCCTGGGCCTGTTGGGTCTCTACATCAATGAGAAGAATGTAGCGCTGGTCAACCAGAACCTGGAGAGCTTGACT
GAGTATTGCCAGGGCCCTTGCCATGAAAATCAGACCTGTATCGCTACACATGAGTCTAATGGGATTGATATCATCATTGCTTTGATTCTG
AATGACATAAACCCTCTTGGTAAATACCGAATGGACCTGGTGCTCCAGCTAAAGAACAATGCATCTAAACTTTTGCTGGCCATTATGGAA
AGCAGACATGACAGTGAGAATGCAGAAAGAATTCTTTTTAACATGAGACCCAGAGAACTGGTGGATGTGATGAAGAATGCCTATAACCAA
GGATTGGAATGTGACCATGGGGATGATGAGGGTGGAGATGATGGTGTTTCTCCAAAAGATGTTGGACACAATATCTATATTCTGGCCCAT
CAGTTGGCCCGCCACAATAAACTGTTGCAGCAGATGCTCAAACCAGGATCGGATCCAGATGAAGGAGATGAAGCCTTAAAGTATTATGCC
AACCACACTGCACAGATTGAGATTGTCCGGCATGATAGGACCATGGAACAAATAGTTTTTCCTGTCCCCAATATATGTGAATACCTCACT
CGAGAATCCAAGTGCCGTGTGTTCAATACAACTGAAAGGGATGAACAAGGAAGTAAAGTGAATGACTTTTTCCAGCAAACAGAAGATCTC
TACAATGAAATGAAGTGGCAGAAGAAAATCAGGAATAACCCTGCACTGTTCTGGTTCTCGAGGCACATCTCTCTCTGGGGGAGCATTTCC
TTCAACCTGGCTGTGTTCATCAATTTAGCTGTTGCTCTCTTCTACCCATTTGGGGATGATGGAGATGAAGGTACACTTTCTCCATTGTTC
TCGGTTCTTCTTTGGATAGCAGTTGCGATCTGCACATCTATGCTGTTTTTCTTCTCCAAGCCTGTGGGTATTCGGCCGTTTCTTGTATCA
ATAATGCTCAGATCAATATATACAATAGGTCTTGGGCCTACATTAATACTTCTTGGTGCAGCTAATCTTTGTAATAAAATTGTTTTTCTG
GTGAGTTTTGTTGGAAATCGTGGCACGTTCACCCGTGGGTACCGAGCAGTCATCCTGGATATGGCCTTTCTCTATCACGTGGCGTATGTC
CTGGTTTGCATGCTGGGCCTTTTTGTCCATGAATTCTTCTATAGCTTCCTGCTTTTTGATTTGGTGTACAGGGAAGAGACTTTGCTGAAT
GTCATAAAAAGTGTCACACGAAATGGCCGCTCTATTATTCTAACTGCAGTCCTGGCTCTCATCCTCGTCTACCTGTTTTCCATTATTGGG
TTCCTTTTTTTGAAGGATGACTTCACTATGGAAGTTGATAGGCTGAAAAACCGAACTCCTGTTACAGGCAGTCATCAAGTGCCTACTATG
ACTTTAACTACCATGATGGAAGCATGTGCCAAGGAGAACTGTTCACCCACAATTCCAGCTTCAAATACAGCTGATGAAGAGTATGAAGAT
GGAATTGAAAGGACGTGTGACACTCTCCTTATGTGCATTGTCACCGTGCTGAACCAGGGCCTCAGGAATGGCGGTGGTGTGGGGGATGTG
CTAAGAAGGCCATCGAAAGATGAGCCCTTGTTTGCTGCCCGAGTGGTTTATGACCTTCTTTTTTATTTCATTGTTATCATTATTGTTCTG
AACTTGATTTTTGGTGTTATCATCGATACTTTTGCTGATCTCAGAAGCGAAAAACAGAAAAAAGAAGAAATTCTAAAGACAACTTGTTTC
ATCTGTGGACTTGAGAGAGACAAGTTTGATAATAAAACGGTTTCATTTGAGGAGCACATTAAGTCAGAACACAATATGTGGCATTATTTG
TACTTCATAGTCCTGGTGAAAGTTAAAGACCCAACAGAATACACTGGACCTGAAAGTTATGTGGCTCAAATGATTGTGGAGAAGAATTTG
GATTGGTTTCCTCGGATGCGAGCCATGTCCCTCGTTAGCAATGAAGGCGACAGTGAGCAAAATGAAATTCGGAGCCTTCAGGAGAAGTTG
GAATCGACCATGAGTCTGGTCAAACAGCTGTCGGGTCAGCTGGCGGAGCTCAAGGAGCAGATGACAGAACAAAGGAAGAATAAGCAGAGA
CTGGGCTTCCTCGGATCAAACACACCCCATGTGAATCATCACATGCCACCACACTGATACCATGGGGGGAAGCCGTGACTAGCCTTTCAT
CAGTGTCCTGCCTGATCACTGAATAAAGAACTGAGATGGAGGGGAGTGAACAGTGCCTATTGTTGAAAAGTTAAAAACAACCAAGTGCCA
AGATGTTGAGTGGGTTAGCTCCGAGAACAATTTATAACTGTGTTTTCATGGTTGCGAAGACCTAACCTCAAATGCATCTGCTAGAAAGCG
TACATCACACATTCGCAATGCATCAGGAAGAAAAGGCTTGCCCAAAAGGCTGGAGAGGGCAGGGAGCGGCAGGATGGAAGGAGACACGGG
GCAGGGAGAACTCTCTTCTGCTAAATCGATAGGAGTCAGTTTTGTCTTAAATGCTGACTACAGCCACTGACATGGTTGGCTGGAATTTCT
TTCTTTTAATTGTGGCATATAGGTTTGTGACACAAGAAGTCATACTTTGGTGGCTAAGTTTTACTAAGGAAAATAACTGAAAAGATTAAA
AGTGAGAGCTGAAAAGAGAAATGATAATGCTTCCAAACTGTAGCTGTCACAGGGCAATTTCTTTATTTATAACATGAAGCACAATGGATT
TACAGCTCTAGGAACTTAGTACTTTGGAGCTTTTGCCTCTCACACTGACAACATAACAGGATGTGATTGCCTTCTCTGGGATTCAGACAG
GCTCTGTCAATGTGGAGCACAAAAGGAGATTTTCATATAACTTGTTAAAAACATGTTCTAAGTCATGTATAGGCTAAGATTTTAAGAAGA
TCTGGGGGAATAAAAAGCCAACAGTAAGCCCCAGGAAAGGGTTTTTTGAGACCATATGTATGCTATTAAAATATATTGAGATTAATACAT
GAAAATGCTTAAAAGTGATAGGAATTATTGAGAAACTTATGATGGTGGCATTGCCTTTTATAAACATGGAGTGAAAGCCATTTGACTCAA
CGTTTGCTGTGCTTAAAGAATTGCTTCAGGACCCGAGCGTTTTTATGTATGCTGTTCCTGCAGTTAGGAAAAAAAAATCCAAGAAATGTA
TTGAATACTCAAGAAAATGCCACATTTCAATTACATATTTAAAACTGTATCTGTAAGGGCTTTTCAAAATGTAGCAAGATAAAAATCTCT
TATTCAAATTGTTTTTGTATTAAATCATGCACTCAGAATTTGTCGAGGGAGAGAATAACCTGGTGTGTTCAGGTTATTCTTAGAGACTAC
ACATTTGGAATAGCAGAGCAAAATATGGATAATGAAAGTGTTGGGAAAAAAGTGATGTGACAGGGAGTGAAGACACTTGATACCAGACTC
TGGGAGATACTCTGCAAGTTGACCTGGCCTCTCCCCCACAGGAACAAAACACTGCCTCCAGAGTCTTTAAATTCTCAGTTATCAACGCCA
AGGTTTAAGGTCTAGATAGGGTTTGCTATAGGGTTTGCTCTGACAATTTTTAAAGCTTTTGGATTGTTCTAACATAGCTTAAGCTATTGG
TTCCTAAAAATCCCAAATCAAGATCTATGTAGAATATAAAGGAAGCCTGAACCAATCCTTCCACATACTGTTAAGATGTAGACTTGGAAC
AAAGCTGTTGGGACCCAGAGCAATGAATTTTTGAACTGAAGCTACTGGTACTCCCCAGCACCACCTCATACTAAGAATTCCTCACTCTGA
CATGACAGTATTTTTTCTGACCAGGAGCTGAAAGACCCTGACATTCATGATCCAAAGATATAAGAAATTTTGATATGTCTGCATGCAGCA
CAGAACTTTGAACCTAGGAGGCAGTCAATAAATACATGAGAAATTCAGCTGTCATTCAGTTACTCTTAATTCTTTATAAAACTTTAAATG
ATACCACATATTTGTTTGTTTAAAATGGCTTTCCCAAAATCAAAGTAGACTAAAGCAGCCATCTTTAAAATCCAGGATCATCAATGCTAT

>83673_83673_2_SLIT3-ITPR2_SLIT3_chr5_168620483_ENST00000404867_ITPR2_chr12_26943160_ENST00000381340_length(amino acids)=2808AA_BP=138
MAPGWAGVGAAVRARLALALALASVLSGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVL
HLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLLVDDRCVVHPEAGDLANPPKKFRDCLFKVCPMNRYSAQKQYW
KAKQAKQGNHTEAALLKKLQHAAELEQKQNESENKKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYI
HPFWKLRSEGDNIVVGDKVVLMPVNAGQPLHASNIELLDNPGCKEVNAVNCNTSWKITLFMKYSSYREDVLKGGDVVRLFHAEQEKFLTC
DEYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVRDGVPPTSKKK
RQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTDEERPVMLKIGTCQTKEDKEAFAIVS
VPLSEVRDLDFANDANKVLATTVKKLENGTITQNERRFVTKLLEDLIFFVADVPNNGQEVLDVVITKPNRERQKLMREQNILAQVFGILK
APFKEKAGEGSMLRLEDLGDQRYAPYKYMLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAK
EIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPGNADILIQTKVVSMQADNPMESSILSDDIDDEEVWLYWIDSNKE
PHGKAIRHLAQEAKEGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQE
SVVPVRYARLWTEIPTKITIHEYDSITDSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELL
RLTRTLLAILDIVQAPMSSYFERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPMSVPDVPPSIHPSKQGSPTEHEDVTVMDTKLKI
IEILQFILSVRLDYRISYMLSIYKKEFGEDNDNAETSASGSPDTLLPSAIVPDIDEIAAQAETMFAGRKEKNPVQLDDEGGRTFLRVLIH
LIMHDYPPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSSNYENGEIGESQVKGGEEPI
EESNILSPVQDGTKKPQIDSNKSNNYRIVKEILIRLSKLCVQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEKNDEKMNEVMNLAHTFLQ
NFCRGNPQNQVLLHKHLNLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDMVMT
ELINGGEDVLIFYNDRASFPILLHMMCSERDRGDESGPLAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAY
VNFVNHCYVDTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRKHADIFLEKCVTESIMNIVSGFFNSPFSDNSTSLQTHQPVFIQLL
QSAFRIYNCTWPNPAQKASVESCIRTLAEVAKNRGIAIPVDLDSQVNTLFMKSHSNMVQRAAMGWRLSARSGPRFKEALGGPAWDYRNII
EKLQDVVASLEHQFSPMMQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINHTKKLMEKEEKLCIKILQTLREMLEKKDSFVEEGN
TLRKILLNRYFKGDYSIGVNGHLSGAYSKTAQVGGSFSGQDSDKMGISMSDIQCLLDKEGASELVIDVIVNTKNDRIFSEGIFLGIALLE
GGNTQTQYSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGNKKRDDDNELMTSGPRMRVRDSTLHLKEGMKGQLTEASSA
TSKAYCVYRREMDPEIDIMCTGPEAGNTEEKSAEEVTMSPAIAIMQPILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCIC
GSTTGGLGLLGLYINEKNVALVNQNLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLGKYRMDLVLQLKNNASKLLLAIME
SRHDSENAERILFNMRPRELVDVMKNAYNQGLECDHGDDEGGDDGVSPKDVGHNIYILAHQLARHNKLLQQMLKPGSDPDEGDEALKYYA
NHTAQIEIVRHDRTMEQIVFPVPNICEYLTRESKCRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSIS
FNLAVFINLAVALFYPFGDDGDEGTLSPLFSVLLWIAVAICTSMLFFFSKPVGIRPFLVSIMLRSIYTIGLGPTLILLGAANLCNKIVFL
VSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIG
FLFLKDDFTMEVDRLKNRTPVTGSHQVPTMTLTTMMEACAKENCSPTIPASNTADEEYEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDV
LRRPSKDEPLFAARVVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYL
YFIVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSNEGDSEQNEIRSLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQR

--------------------------------------------------------------
>83673_83673_3_SLIT3-ITPR2_SLIT3_chr5_168620483_ENST00000519560_ITPR2_chr12_26943160_ENST00000381340_length(transcript)=10835nt_BP=833nt
GAGAGCGAGCGCCGGCCAGCTCACCCGGCCGCCCCGTGCCCCAGCCGCAGCCGCCGCGCTCCCCAGCCCAGCCCCAAGCCGGACCTCCCC
GGGCGCCACGCCCCATTGCGCTCGCCCCAGGTCCCCAACCCGGCCCGCGGGCCAGCGGGGCCAGGGGGCGCTCCGCACCTGGGCACTCCC
AGCGATGCGCAGCGGGGCAGCGCCGGCCCCGCCGATGGAGCTGCTGTTGCTGCCGCCGCCGCCGCCCGGAGCGCCCCGCTCCGCCCGCGC
CCCGTGCGCCTGAGCACCGAGCTCGCCCCTCCTCCGCGCTAACTCCGCCGCCCGCTCCCCAGGCCGCCCGCGCTCCCCGCGCGCCTCCTC
GGGCTCCACGCGTCTTGCCCCGCAGAGGCAGCCTCCTCCAGGAGCGGGGCCCTGCACACCATGGCCCCCGGGTGGGCAGGGGTCGGCGCC
GCCGTGCGCGCCCGCCTGGCGCTGGCCTTGGCGCTGGCGAGCGTCCTGAGTGGGCCTCCAGCCGTCGCCTGCCCCACCAAGTGTACCTGC
TCCGCTGCCAGCGTGGACTGCCACGGGCTGGGCCTCCGCGCGGTTCCTCGGGGCATCCCCCGCAACGCTGAGCGCCTTGACCTGGACAGA
AATAATATCACCAGGATCACCAAGATGGACTTCGCTGGGCTCAAGAACCTCCGAGTCTTGCATCTGGAAGACAACCAGGTCAGCGTCATC
GAGAGAGGCGCCTTCCAGGACCTGAAGCAGCTAGAGCGACTGCGCCTGAACAAGAATAAGCTGCAAGTCCTTCCAGAATTGCTTTTCCAG
AGCACGCCGAAGCTCACCAGACTGTTAGTGGATGACAGATGTGTGGTGCACCCAGAGGCCGGGGACCTTGCCAACCCTCCCAAGAAGTTC
AGAGACTGCCTTTTCAAGGTGTGCCCTATGAACAGATATTCTGCCCAGAAGCAATATTGGAAAGCAAAGCAAGCCAAACAAGGGAACCAC
ACCGAGGCAGCCTTGCTGAAGAAACTACAGCACGCTGCAGAACTGGAACAAAAACAAAATGAATCGGAGAATAAGAAACTGTTGGGAGAA
ATTGTAAAATACAGTAATGTTATACAACTACTGCATATAAAAAGCAACAAATATCTTACTGTCAACAAGAGATTACCTGCTTTACTGGAG
AAGAATGCCATGCGTGTGTCCTTGGATGCTGCAGGAAATGAAGGGTCTTGGTTTTATATTCATCCGTTCTGGAAACTGAGAAGCGAGGGT
GACAATATTGTTGTAGGAGATAAAGTTGTTTTGATGCCTGTGAATGCAGGGCAGCCACTACATGCCAGCAACATAGAGCTTCTTGATAAC
CCAGGGTGTAAAGAGGTGAATGCTGTCAATTGCAACACCAGCTGGAAAATCACTTTATTCATGAAATATAGTTCCTATCGAGAGGATGTA
TTAAAAGGAGGGGACGTTGTTAGATTATTTCATGCGGAACAAGAGAAGTTTTTGACTTGTGATGAATATGAGAAAAAACAGCACATTTTC
CTTCGTACGACCTTGCGCCAATCAGCTACTTCTGCTACTAGTTCTAAAGCACTCTGGGAAATAGAGGTGGTTCATCATGACCCATGCCGT
GGGGGTGCAGGACAGTGGAACAGCTTGTTCAGATTTAAGCATCTTGCAACTGGAAACTATTTAGCTGCAGAGCTTAATCCTGATTATCGA
GATGCCCAAAATGAAGGAAAAAATGTGAGAGATGGAGTCCCTCCAACTTCAAAGAAAAAACGCCAGGCAGGGGAGAAGATCATGTATACT
TTGGTTTCAGTCCCGCATGGCAATGACATTGCATCCCTTTTTGAACTAGATGCCACAACTCTTCAGAGAGCTGACTGCCTGGTTCCAAGG
AACTCATATGTTCGGTTAAGGCATTTATGCACCAACACATGGGTAACCAGTACTAGTATCCCCATAGACACAGATGAAGAGAGGCCTGTT
ATGTTAAAGATTGGAACCTGCCAAACCAAAGAAGATAAAGAAGCGTTCGCAATCGTGTCTGTTCCACTGTCTGAAGTTCGAGACTTAGAC
TTTGCCAATGATGCCAATAAAGTACTAGCGACCACAGTTAAAAAGCTAGAAAACGGCACAATAACTCAGAATGAAAGGAGGTTTGTAACC
AAATTATTGGAAGATCTCATATTCTTTGTTGCTGATGTGCCTAATAATGGACAAGAAGTTCTGGATGTGGTTATCACTAAGCCAAACCGA
GAGCGTCAAAAATTGATGAGGGAACAAAACATACTGGCACAGGTATTTGGAATTCTTAAAGCACCCTTTAAAGAGAAAGCAGGAGAAGGC
TCGATGCTGAGACTTGAAGATCTGGGGGATCAAAGATATGCACCCTACAAGTACATGCTGCGGCTCTGTTACCGCGTCCTGAGACACTCG
CAGCAGGATTACCGGAAAAATCAGGAATATATTGCTAAGAATTTCTGTGTCATGCAGTCCCAGATTGGCTATGATATTTTGGCAGAAGAT
ACTATCACAGCTTTGTTGCACAACAACAGAAAACTACTAGAGAAACATATCACAGCAAAAGAAATAGAAACATTTGTCAGTTTACTCAGG
AGAAATCGGGAGCCAAGGTTTTTGGATTATTTGTCAGATCTGTGTGTGTCTAATACCACTGCTATCCCTGTAACTCAAGAACTCATCTGT
AAATTTATGTTGAGTCCAGGCAATGCAGACATTCTCATTCAAACTAAGGTGGTCTCAATGCAAGCAGACAACCCCATGGAGAGCTCCATC
CTTTCAGATGACATTGATGATGAAGAAGTTTGGCTCTATTGGATTGACAGCAACAAGGAACCTCATGGCAAAGCTATCAGGCACCTTGCT
CAAGAGGCAAAAGAAGGCACCAAAGCTGACTTAGAAGTTCTTACCTATTACAGGTACCAGCTAAACCTCTTTGCAAGGATGTGCTTGGAT
CGCCAGTATCTGGCCATAAACCAGATTTCTACACAGCTGTCTGTAGACCTGATCCTGCGGTGTGTGTCGGATGAGAGCCTGCCGTTCGAC
CTCCGAGCGTCCTTCTGTCGCCTCATGCTCCACATGCACGTTGACCGGGATCCCCAGGAGTCCGTGGTGCCTGTTCGCTATGCCAGGCTC
TGGACAGAAATCCCCACAAAGATCACAATTCATGAATATGATTCTATAACAGACTCTTCCAGAAATGATATGAAGAGGAAATTTGCCCTG
ACAATGGAATTTGTTGAAGAATATTTGAAAGAAGTTGTAAACCAGCCCTTTCCTTTTGGGGATAAAGAAAAAAATAAACTGACATTTGAG
GTGGTCCACTTGGCTCGGAATCTTATATACTTTGGATTTTATAGTTTCAGTGAGTTATTAAGGCTAACAAGAACACTTCTGGCTATTTTA
GACATTGTACAGGCCCCCATGTCATCATACTTTGAAAGATTAAGCAAATTTCAAGATGGAGGAAACAATGTGATGAGAACCATTCATGGG
GTGGGAGAGATGATGACCCAGATGGTACTCAGTAGAGGCTCCATCTTCCCCATGAGCGTGCCGGATGTGCCACCCAGCATCCACCCGAGC
AAGCAAGGGAGCCCCACCGAGCACGAGGATGTGACTGTGATGGACACCAAGCTGAAGATCATTGAGATTTTGCAGTTTATCCTGAGTGTC
AGACTGGATTATAGGATCTCATATATGCTGTCAATATATAAGAAGGAGTTTGGAGAGGACAATGACAATGCGGAGACATCTGCCAGTGGA
TCTCCAGACACTTTACTACCATCAGCTATTGTTCCTGATATAGATGAAATTGCAGCTCAGGCAGAAACTATGTTTGCGGGAAGAAAAGAA
AAAAATCCAGTTCAACTTGACGATGAAGGAGGCAGGACGTTTTTACGGGTCCTCATTCATCTGATCATGCACGACTACCCGCCTTTGCTG
TCTGGAGCCCTGCAGCTGTTGTTTAAGCACTTCAGCCAGAGGGCAGAGGTTTTACAGGCATTTAAGCAGGTGCAATTACTGGTGTCTAAT
CAAGACGTAGATAACTACAAGCAAATCAAGGCAGATCTAGACCAGCTTCGACTGACAGTAGAAAAGTCTGAGCTATGGGTGGAGAAGAGC
AGCAACTATGAGAATGGAGAAATAGGGGAAAGTCAAGTGAAAGGTGGTGAAGAGCCAATTGAGGAATCAAACATTTTAAGTCCAGTGCAG
GATGGAACAAAGAAACCTCAGATTGACAGCAACAAGAGCAATAACTACCGGATTGTAAAGGAGATTTTGATCAGGCTAAGTAAACTCTGT
GTGCAGAATAAAAAGTGTCGGAATCAACATCAACGATTACTGAAAAATATGGGGGCGCATTCGGTGGTGTTGGATCTTCTGCAGATACCC
TATGAAAAGAATGATGAAAAGATGAATGAAGTAATGAATCTAGCCCATACATTTCTGCAGAATTTCTGTCGAGGAAATCCACAGAATCAA
GTTCTTCTTCATAAACATCTGAATTTGTTTTTAACTCCAGGTCTCCTTGAAGCAGAAACCATGCGGCACATCTTCATGAACAATTACCAT
CTGTGCAACGAAATTAGCGAGAGAGTTGTACAACACTTTGTGCACTGCATTGAGACACATGGCCGCCACGTGGAGTACCTGAGGTTTTTG
CAAACAATTGTAAAAGCAGATGGTAAATATGTGAAGAAATGCCAGGATATGGTAATGACAGAGTTGATAAATGGGGGTGAAGACGTGCTG
ATATTTTACAATGATAGAGCATCATTTCCAATCCTTCTCCATATGATGTGTTCAGAGAGAGACCGAGGGGATGAGAGTGGCCCCTTAGCC
TACCACATCACCCTGGTGGAGTTGCTGGCAGCATGCACAGAGGGGAAAAATGTCTACACTGAAATCAAGTGTAATTCCCTTCTCCCGCTG
GACGACATAGTGAGGGTGGTGACCCATGACGACTGCATCCCTGAGGTTAAAATTGCTTATGTGAACTTTGTTAATCACTGTTATGTTGAC
ACTGAAGTGGAAATGAAAGAAATCTATACAAGTAACCACATTTGGAAATTATTTGAGAACTTCTTGGTGGATATGGCAAGGGTTTGCAAC
ACAACTACAGACAGGAAACATGCAGACATCTTTTTGGAAAAGTGTGTTACTGAGTCAATAATGAATATTGTGAGCGGCTTCTTTAATTCT
CCCTTTTCAGACAATAGTACCAGCCTCCAGACACATCAGCCAGTTTTTATTCAGCTACTGCAATCTGCCTTCAGAATTTACAATTGCACC
TGGCCAAACCCAGCGCAGAAAGCCTCAGTGGAATCCTGTATCAGAACTTTGGCTGAAGTGGCAAAAAATCGTGGAATTGCCATTCCAGTG
GATTTGGACAGCCAAGTTAATACTCTTTTCATGAAGAGCCATTCAAATATGGTGCAGAGAGCAGCAATGGGTTGGAGACTATCAGCTCGC
TCTGGGCCACGCTTTAAGGAAGCTCTTGGAGGGCCTGCTTGGGATTACAGAAATATTATTGAAAAGTTACAGGATGTAGTGGCCTCCTTG
GAGCACCAGTTCAGCCCAATGATGCAGGCTGAATTCTCAGTGTTGGTTGATGTATTGTACAGTCCAGAACTGCTGTTCCCTGAGGGAAGC
GATGCAAGAATAAGATGTGGCGCTTTCATGTCGAAGTTGATTAATCATACAAAGAAACTAATGGAGAAAGAAGAAAAACTGTGCATTAAA
ATTCTTCAGACATTACGAGAAATGTTAGAGAAGAAAGACAGCTTTGTGGAAGAGGGTAACACATTAAGAAAGATACTTCTGAATCGATAC
TTTAAAGGTGATTATAGTATTGGTGTGAATGGACACCTATCAGGAGCCTACTCCAAAACTGCACAGGTGGGAGGAAGCTTTTCTGGACAA
GATTCAGATAAGATGGGGATATCAATGTCAGACATTCAGTGTCTGCTGGATAAAGAAGGTGCATCAGAACTTGTCATCGATGTTATAGTG
AACACCAAAAATGACAGAATTTTTTCAGAAGGCATTTTCCTCGGCATTGCCTTGCTTGAAGGAGGAAATACACAAACACAGTATTCTTTC
TACCAGCAGTTGCATGAACAAAAAAAGTCAGAAAAATTCTTTAAAGTTCTCTATGATCGAATGAAGGCTGCTCAGAAAGAAATAAGATCA
ACAGTGACAGTTAATACCATAGATTTAGGTAACAAAAAAAGGGACGATGACAATGAATTGATGACATCTGGTCCACGAATGAGAGTAAGA
GATTCAACACTACATTTAAAAGAGGGAATGAAAGGGCAATTAACAGAAGCTTCTTCAGCAACATCCAAAGCATATTGTGTATACAGAAGA
GAAATGGATCCAGAAATAGACATTATGTGCACAGGACCAGAAGCGGGAAACACTGAGGAAAAATCCGCAGAGGAAGTAACAATGAGTCCC
GCAATTGCCATCATGCAGCCAATACTGAGATTTCTTCAGTTACTGTGTGAGAATCACAACCGGGAATTGCAGAACTTCTTGAGGAATCAA
AACAACAAAACAAATTACAACCTAGTCTGTGAGACCCTTCAGTTTCTGGACTGCATTTGTGGAAGTACAACCGGTGGCCTGGGCCTGTTG
GGTCTCTACATCAATGAGAAGAATGTAGCGCTGGTCAACCAGAACCTGGAGAGCTTGACTGAGTATTGCCAGGGCCCTTGCCATGAAAAT
CAGACCTGTATCGCTACACATGAGTCTAATGGGATTGATATCATCATTGCTTTGATTCTGAATGACATAAACCCTCTTGGTAAATACCGA
ATGGACCTGGTGCTCCAGCTAAAGAACAATGCATCTAAACTTTTGCTGGCCATTATGGAAAGCAGACATGACAGTGAGAATGCAGAAAGA
ATTCTTTTTAACATGAGACCCAGAGAACTGGTGGATGTGATGAAGAATGCCTATAACCAAGGATTGGAATGTGACCATGGGGATGATGAG
GGTGGAGATGATGGTGTTTCTCCAAAAGATGTTGGACACAATATCTATATTCTGGCCCATCAGTTGGCCCGCCACAATAAACTGTTGCAG
CAGATGCTCAAACCAGGATCGGATCCAGATGAAGGAGATGAAGCCTTAAAGTATTATGCCAACCACACTGCACAGATTGAGATTGTCCGG
CATGATAGGACCATGGAACAAATAGTTTTTCCTGTCCCCAATATATGTGAATACCTCACTCGAGAATCCAAGTGCCGTGTGTTCAATACA
ACTGAAAGGGATGAACAAGGAAGTAAAGTGAATGACTTTTTCCAGCAAACAGAAGATCTCTACAATGAAATGAAGTGGCAGAAGAAAATC
AGGAATAACCCTGCACTGTTCTGGTTCTCGAGGCACATCTCTCTCTGGGGGAGCATTTCCTTCAACCTGGCTGTGTTCATCAATTTAGCT
GTTGCTCTCTTCTACCCATTTGGGGATGATGGAGATGAAGGTACACTTTCTCCATTGTTCTCGGTTCTTCTTTGGATAGCAGTTGCGATC
TGCACATCTATGCTGTTTTTCTTCTCCAAGCCTGTGGGTATTCGGCCGTTTCTTGTATCAATAATGCTCAGATCAATATATACAATAGGT
CTTGGGCCTACATTAATACTTCTTGGTGCAGCTAATCTTTGTAATAAAATTGTTTTTCTGGTGAGTTTTGTTGGAAATCGTGGCACGTTC
ACCCGTGGGTACCGAGCAGTCATCCTGGATATGGCCTTTCTCTATCACGTGGCGTATGTCCTGGTTTGCATGCTGGGCCTTTTTGTCCAT
GAATTCTTCTATAGCTTCCTGCTTTTTGATTTGGTGTACAGGGAAGAGACTTTGCTGAATGTCATAAAAAGTGTCACACGAAATGGCCGC
TCTATTATTCTAACTGCAGTCCTGGCTCTCATCCTCGTCTACCTGTTTTCCATTATTGGGTTCCTTTTTTTGAAGGATGACTTCACTATG
GAAGTTGATAGGCTGAAAAACCGAACTCCTGTTACAGGCAGTCATCAAGTGCCTACTATGACTTTAACTACCATGATGGAAGCATGTGCC
AAGGAGAACTGTTCACCCACAATTCCAGCTTCAAATACAGCTGATGAAGAGTATGAAGATGGAATTGAAAGGACGTGTGACACTCTCCTT
ATGTGCATTGTCACCGTGCTGAACCAGGGCCTCAGGAATGGCGGTGGTGTGGGGGATGTGCTAAGAAGGCCATCGAAAGATGAGCCCTTG
TTTGCTGCCCGAGTGGTTTATGACCTTCTTTTTTATTTCATTGTTATCATTATTGTTCTGAACTTGATTTTTGGTGTTATCATCGATACT
TTTGCTGATCTCAGAAGCGAAAAACAGAAAAAAGAAGAAATTCTAAAGACAACTTGTTTCATCTGTGGACTTGAGAGAGACAAGTTTGAT
AATAAAACGGTTTCATTTGAGGAGCACATTAAGTCAGAACACAATATGTGGCATTATTTGTACTTCATAGTCCTGGTGAAAGTTAAAGAC
CCAACAGAATACACTGGACCTGAAAGTTATGTGGCTCAAATGATTGTGGAGAAGAATTTGGATTGGTTTCCTCGGATGCGAGCCATGTCC
CTCGTTAGCAATGAAGGCGACAGTGAGCAAAATGAAATTCGGAGCCTTCAGGAGAAGTTGGAATCGACCATGAGTCTGGTCAAACAGCTG
TCGGGTCAGCTGGCGGAGCTCAAGGAGCAGATGACAGAACAAAGGAAGAATAAGCAGAGACTGGGCTTCCTCGGATCAAACACACCCCAT
GTGAATCATCACATGCCACCACACTGATACCATGGGGGGAAGCCGTGACTAGCCTTTCATCAGTGTCCTGCCTGATCACTGAATAAAGAA
CTGAGATGGAGGGGAGTGAACAGTGCCTATTGTTGAAAAGTTAAAAACAACCAAGTGCCAAGATGTTGAGTGGGTTAGCTCCGAGAACAA
TTTATAACTGTGTTTTCATGGTTGCGAAGACCTAACCTCAAATGCATCTGCTAGAAAGCGTACATCACACATTCGCAATGCATCAGGAAG
AAAAGGCTTGCCCAAAAGGCTGGAGAGGGCAGGGAGCGGCAGGATGGAAGGAGACACGGGGCAGGGAGAACTCTCTTCTGCTAAATCGAT
AGGAGTCAGTTTTGTCTTAAATGCTGACTACAGCCACTGACATGGTTGGCTGGAATTTCTTTCTTTTAATTGTGGCATATAGGTTTGTGA
CACAAGAAGTCATACTTTGGTGGCTAAGTTTTACTAAGGAAAATAACTGAAAAGATTAAAAGTGAGAGCTGAAAAGAGAAATGATAATGC
TTCCAAACTGTAGCTGTCACAGGGCAATTTCTTTATTTATAACATGAAGCACAATGGATTTACAGCTCTAGGAACTTAGTACTTTGGAGC
TTTTGCCTCTCACACTGACAACATAACAGGATGTGATTGCCTTCTCTGGGATTCAGACAGGCTCTGTCAATGTGGAGCACAAAAGGAGAT
TTTCATATAACTTGTTAAAAACATGTTCTAAGTCATGTATAGGCTAAGATTTTAAGAAGATCTGGGGGAATAAAAAGCCAACAGTAAGCC
CCAGGAAAGGGTTTTTTGAGACCATATGTATGCTATTAAAATATATTGAGATTAATACATGAAAATGCTTAAAAGTGATAGGAATTATTG
AGAAACTTATGATGGTGGCATTGCCTTTTATAAACATGGAGTGAAAGCCATTTGACTCAACGTTTGCTGTGCTTAAAGAATTGCTTCAGG
ACCCGAGCGTTTTTATGTATGCTGTTCCTGCAGTTAGGAAAAAAAAATCCAAGAAATGTATTGAATACTCAAGAAAATGCCACATTTCAA
TTACATATTTAAAACTGTATCTGTAAGGGCTTTTCAAAATGTAGCAAGATAAAAATCTCTTATTCAAATTGTTTTTGTATTAAATCATGC
ACTCAGAATTTGTCGAGGGAGAGAATAACCTGGTGTGTTCAGGTTATTCTTAGAGACTACACATTTGGAATAGCAGAGCAAAATATGGAT
AATGAAAGTGTTGGGAAAAAAGTGATGTGACAGGGAGTGAAGACACTTGATACCAGACTCTGGGAGATACTCTGCAAGTTGACCTGGCCT
CTCCCCCACAGGAACAAAACACTGCCTCCAGAGTCTTTAAATTCTCAGTTATCAACGCCAAGGTTTAAGGTCTAGATAGGGTTTGCTATA
GGGTTTGCTCTGACAATTTTTAAAGCTTTTGGATTGTTCTAACATAGCTTAAGCTATTGGTTCCTAAAAATCCCAAATCAAGATCTATGT
AGAATATAAAGGAAGCCTGAACCAATCCTTCCACATACTGTTAAGATGTAGACTTGGAACAAAGCTGTTGGGACCCAGAGCAATGAATTT
TTGAACTGAAGCTACTGGTACTCCCCAGCACCACCTCATACTAAGAATTCCTCACTCTGACATGACAGTATTTTTTCTGACCAGGAGCTG
AAAGACCCTGACATTCATGATCCAAAGATATAAGAAATTTTGATATGTCTGCATGCAGCACAGAACTTTGAACCTAGGAGGCAGTCAATA
AATACATGAGAAATTCAGCTGTCATTCAGTTACTCTTAATTCTTTATAAAACTTTAAATGATACCACATATTTGTTTGTTTAAAATGGCT
TTCCCAAAATCAAAGTAGACTAAAGCAGCCATCTTTAAAATCCAGGATCATCAATGCTATTAACAGTATCAGGTAAAAAGTACACTTTAA

>83673_83673_3_SLIT3-ITPR2_SLIT3_chr5_168620483_ENST00000519560_ITPR2_chr12_26943160_ENST00000381340_length(amino acids)=2811AA_BP=141
MHTMAPGWAGVGAAVRARLALALALASVLSGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNL
RVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLLVDDRCVVHPEAGDLANPPKKFRDCLFKVCPMNRYSAQK
QYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENKKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSW
FYIHPFWKLRSEGDNIVVGDKVVLMPVNAGQPLHASNIELLDNPGCKEVNAVNCNTSWKITLFMKYSSYREDVLKGGDVVRLFHAEQEKF
LTCDEYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVRDGVPPTS
KKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTDEERPVMLKIGTCQTKEDKEAFA
IVSVPLSEVRDLDFANDANKVLATTVKKLENGTITQNERRFVTKLLEDLIFFVADVPNNGQEVLDVVITKPNRERQKLMREQNILAQVFG
ILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYMLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHI
TAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPGNADILIQTKVVSMQADNPMESSILSDDIDDEEVWLYWIDS
NKEPHGKAIRHLAQEAKEGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRD
PQESVVPVRYARLWTEIPTKITIHEYDSITDSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFS
ELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPMSVPDVPPSIHPSKQGSPTEHEDVTVMDTK
LKIIEILQFILSVRLDYRISYMLSIYKKEFGEDNDNAETSASGSPDTLLPSAIVPDIDEIAAQAETMFAGRKEKNPVQLDDEGGRTFLRV
LIHLIMHDYPPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSSNYENGEIGESQVKGGE
EPIEESNILSPVQDGTKKPQIDSNKSNNYRIVKEILIRLSKLCVQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEKNDEKMNEVMNLAHT
FLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDM
VMTELINGGEDVLIFYNDRASFPILLHMMCSERDRGDESGPLAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVK
IAYVNFVNHCYVDTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRKHADIFLEKCVTESIMNIVSGFFNSPFSDNSTSLQTHQPVFI
QLLQSAFRIYNCTWPNPAQKASVESCIRTLAEVAKNRGIAIPVDLDSQVNTLFMKSHSNMVQRAAMGWRLSARSGPRFKEALGGPAWDYR
NIIEKLQDVVASLEHQFSPMMQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINHTKKLMEKEEKLCIKILQTLREMLEKKDSFVE
EGNTLRKILLNRYFKGDYSIGVNGHLSGAYSKTAQVGGSFSGQDSDKMGISMSDIQCLLDKEGASELVIDVIVNTKNDRIFSEGIFLGIA
LLEGGNTQTQYSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGNKKRDDDNELMTSGPRMRVRDSTLHLKEGMKGQLTEA
SSATSKAYCVYRREMDPEIDIMCTGPEAGNTEEKSAEEVTMSPAIAIMQPILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLD
CICGSTTGGLGLLGLYINEKNVALVNQNLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLGKYRMDLVLQLKNNASKLLLA
IMESRHDSENAERILFNMRPRELVDVMKNAYNQGLECDHGDDEGGDDGVSPKDVGHNIYILAHQLARHNKLLQQMLKPGSDPDEGDEALK
YYANHTAQIEIVRHDRTMEQIVFPVPNICEYLTRESKCRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWG
SISFNLAVFINLAVALFYPFGDDGDEGTLSPLFSVLLWIAVAICTSMLFFFSKPVGIRPFLVSIMLRSIYTIGLGPTLILLGAANLCNKI
VFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFS
IIGFLFLKDDFTMEVDRLKNRTPVTGSHQVPTMTLTTMMEACAKENCSPTIPASNTADEEYEDGIERTCDTLLMCIVTVLNQGLRNGGGV
GDVLRRPSKDEPLFAARVVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMW
HYLYFIVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSNEGDSEQNEIRSLQEKLESTMSLVKQLSGQLAELKEQMTEQRKN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SLIT3-ITPR2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SLIT3-ITPR2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SLIT3-ITPR2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource